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1 activation of the receptor tyrosine kinases, platelet-derived and epidermal growth factor receptors.
2 gery, cases had 2- and 4-fold more activated platelet-derived and tissue-factor positive MVs respecti
3 Tie-2 agonist and its source, we found that platelet-derived angiopoietin-1 (Angpt1) was required to
4 immunity: conferring intrinsic resistance to platelet-derived antimicrobial components and inhibiting
6 ue-coinfected patients, plasma levels of the platelet-derived chemokines RANTES/CCL5 and PF4/CXCL4 we
9 endothelial cell-derived exosomes (EDEs) and platelet-derived exosomes (PDEs) were precipitated and e
13 ly suppressed cargo protein levels of plasma platelet-derived exosomes without altering total levels
19 individual completely devoid of plasma- and platelet-derived factor V (FV) identified 167 variants i
25 In marked contrast, release of the patient's platelet-derived FV/Va (7% of normal) following platelet
27 l, thereby highlighting the critical role of platelet-derived FV/Va in ensuring hemostatic competence
29 tion of matrix-associated GFs, TGF-beta, and platelet-derived GF to GF(-) or culture supernatants.
36 ent of known imatinib targets including Abl, platelet derived growth factor receptor beta (PDGFRbeta)
37 present study was to evaluate the levels of platelet derived growth factor-BB (PDGF-BB) in gingival
38 ession of the spliced XBP1 or treatment with platelet derived growth factor-BB up-regulated miR-150 e
39 tors such as tumor necrosis factor-alpha and platelet derived growth factor-BB were also found to inc
44 e involved in the lipopolysaccharide-induced platelet-derived growth factor (PDGF) and Wnt signaling
45 10030 (Fovista; Ophthotech, New York, NY), a platelet-derived growth factor (PDGF) antagonist, admini
46 agonist [WAY-200070 (WAY)] with TNF-alpha or platelet-derived growth factor (PDGF) followed by evalua
47 rowth factors, the most representative being platelet-derived growth factor (PDGF) isoforms (PDGF-AA,
48 ied KCE method to an experimental model of a platelet-derived growth factor (PDGF) protein and its DN
51 ascular endothelial growth factor (VEGF) and platelet-derived growth factor (PDGF) receptors, has sin
52 roblast chemotaxis directed by a gradient of platelet-derived growth factor (PDGF) requires signaling
53 -of-function alterations leading to enhanced platelet-derived growth factor (PDGF) signaling are comm
56 optical biosensing modulation by insulin and platelet-derived growth factor (PDGF) using the Aptamer-
57 ng a small interfering RNA (siRNA) targeting platelet-derived growth factor (PDGF) was used to allevi
59 clotted wound by a concentration gradient of platelet-derived growth factor (PDGF), together with oth
60 s transforming growth factor-beta (TGFbeta), platelet-derived growth factor (PDGF), WNT and hedgehog
64 EDE levels of VCAM-1, von Willebrand factor, platelet-derived growth factor (PDGF)-BB, angiopoietin-1
66 angiogenic factors, friend of Gata 2 (FOG2), platelet-derived growth factor (PDGF)-beta, and phosphat
68 e discovery of a novel ligand for PDGFRbeta, platelet-derived growth factor (PDGF)-DD, opened the pos
70 d quiescent mesenchymal cell activation in a platelet-derived growth factor (PDGF)-dependent manner.
72 ted knockdown of TRIM28 and TRIM27 inhibited platelet-derived growth factor (PDGF)-induced migration
74 EC was uniformly inhibited by combined VEGF/platelet-derived growth factor (PDGF)/FGF receptor inhib
75 ular endothelial growth factor (VEGF) and 2) platelet-derived growth factor (PDGF-BB) in gingival cre
76 1 overexpression increases the expression of platelet-derived growth factor (PDGFB) in human pulmonar
77 sforming growth factor beta 1 (TGFbeta1) and platelet-derived growth factor (PDGFbetabeta) stimulatio
79 r receptor alpha (PDGFRalpha) and its ligand platelet-derived growth factor A (PDGF-A) are co-express
81 s (angiopoietin 2; hepatocyte growth factor; platelet-derived growth factor AA and BB; placental grow
82 [TGF-beta1], epidermal growth factor [EGF], platelet-derived growth factor AB [PDGF-AB], and albumin
83 tor, vascular endothelial growth factor, and platelet-derived growth factor AB) before and after comp
86 1, and transiently suppressed myofibroblast platelet-derived growth factor alpha differentiation mar
87 a similar level of TNF-alpha, TGF-beta1, and platelet-derived growth factor alpha genes, and a high l
90 , myogenesis regulating glycosidase (MYORG), platelet-derived growth factor B (PDGFB) and platelet-de
92 ar endothelial growth factor A (VEGF-A), and platelet-derived growth factor B chain (PDGF-BB), to sti
93 expression of vascular endothelial cadherin, platelet-derived growth factor B, S1P(1), and CCN1 (mole
94 r receptor in mice bearing RCAS/tv-a-induced platelet-derived growth factor B-overexpressing glioblas
96 h, we demonstrate that two of these pathways-platelet-derived growth factor BB (PDGF BB) and neural p
97 study participants, the angiogenic cytokine platelet-derived growth factor BB glycoprotein correlate
99 sely, PCSK6 overexpression increased PDGFBB (platelet-derived growth factor BB)-induced cell prolifer
100 henotype was hyperproliferative to serum and platelet-derived growth factor BB, and unresponsive to t
101 ombination of lentiviral vectors, expressing platelet-derived growth factor beta (PDGF-B), constituti
103 sessed relationships between tau and soluble platelet-derived growth factor beta (sPDGFRbeta), a CSF
104 nds to the transmembrane domain (TMD) of the platelet-derived growth factor beta receptor (PDGFbetaR)
105 ing smooth muscle alpha-actin (alphaSMA) and platelet-derived growth factor beta receptor (PDGFbetaR)
106 le amino acid substitutions can activate the platelet-derived growth factor beta receptor or the eryt
108 sions of fibrosis-related proteins including platelet-derived growth factor beta, fibronectin and col
109 nteract with the transmembrane domain of the platelet-derived growth factor beta-receptor and specifi
111 in, tissue inhibitor of metalloproteinase 1, platelet-derived growth factor c, transforming growth fa
113 layed by transforming growth factor-beta and platelet-derived growth factor D in driving the recruitm
114 phages, T cells, and platelets and increased platelet-derived growth factor D, Pdgfrb, Itga2, and mat
116 ulture self-assembled into microvessels, and platelet-derived growth factor had chemotactic effect on
117 razin-2(1H)-ones toward potent and effective platelet-derived growth factor receptor (PDGF-R) beta-in
118 ng fibroblast growth factor receptor (FGFR), platelet-derived growth factor receptor (PDGFR) and inte
121 YR mice had significantly reduced amounts of platelet-derived growth factor receptor (PDGFR), which i
123 isib also inhibited ALL proliferation in ABL/platelet-derived growth factor receptor (PDGFR)-mutant m
124 Anterograde transport mutants display low platelet-derived growth factor receptor (PDGFR)alpha lev
125 2), their coreceptor neuropilin1 (NRP1), and platelet-derived growth factor receptor (PDGFRalpha and
126 luded expected PI3K interactors, such as the platelet-derived growth factor receptor A (PDGFRA), as w
128 GG), often in association with TP53 loss and platelet-derived growth factor receptor alpha (PDGFRA) a
129 rized by an oncogenic mutation in the KIT or platelet-derived growth factor receptor alpha (PDGFRA) g
131 ncogene, receptor tyrosine kinase (KIT), and platelet-derived growth factor receptor alpha (PDGFRA) i
132 -oncogene receptor tyrosine kinase (KIT) and platelet-derived growth factor receptor alpha (PDGFRA) m
133 a CRISPR/Cas9 strategy identified guinea pig platelet-derived growth factor receptor alpha (PDGFRA) t
134 errations in FLT3, tyrosine kinase 2 (TYK2), platelet-derived growth factor receptor alpha (PDGFRA),
138 many different signaling pathways, including platelet-derived growth factor receptor alpha (PDGFRalph
140 ellular origin of new myelin by fate mapping platelet-derived growth factor receptor alpha (PDGFRalph
141 l cells of Cajal (ICC), and cells expressing platelet-derived growth factor receptor alpha (PDGFRalph
142 a poor prognosis and exhibit an increase in platelet-derived growth factor receptor alpha (PDGFRalph
144 that TAg expression reduces the abundance of platelet-derived growth factor receptor alpha (PDGFRalph
146 l cells of Cajal (ICC), and cells expressing platelet-derived growth factor receptor alpha (PDGFRalph
148 tion of H3.3 K27M cooperated with activating platelet-derived growth factor receptor alpha (PDGFRalph
149 f cone-driven photoresponses, were bred with platelet-derived growth factor receptor alpha (Pdgfralph
150 ssed in primitive stromal cells that express platelet-derived growth factor receptor alpha and Sca-1
151 SMCs), interstitial cells of Cajal (ICC) and platelet-derived growth factor receptor alpha positive (
152 more, oncogenic RAB35 is sufficient to drive platelet-derived growth factor receptor alpha to LAMP2-p
154 led alpha1 adrenoceptors (ARs) expression in platelet-derived growth factor receptor alpha(+) cells (
155 Populations of enteric neurons, ICC, and platelet-derived growth factor receptor alpha(+) cells w
156 differentiated alpha-smooth muscle actin(+)/platelet-derived growth factor receptor alpha(+)/CD44(+)
157 atrix by increasing nonmuscle myosin II- and platelet-derived growth factor receptor alpha-mediated c
158 press the mesenchymal stem cell (MSC) marker platelet-derived growth factor receptor alpha; hence, we
159 N, resulting in increased phosphorylation of platelet-derived growth factor receptor and activation o
161 ranscriptional response to Mucorales reveals platelet-derived growth factor receptor B (PDGFRB) signa
162 n profiling, which revealed up-regulation of platelet-derived growth factor receptor beta (Pdgfrb) an
163 platelet-derived growth factor B (PDGFB) and platelet-derived growth factor receptor beta (PDGFRB), a
166 reased the catalytic loop phosphorylation of platelet-derived growth factor receptor beta (PDGFRbeta)
167 Gint4.T aptamer specifically recognizes platelet-derived growth factor receptor beta and can cro
168 mooth muscle cells (ISMC) with expression of platelet-derived growth factor receptor beta and progres
169 [GRCh37/hg19]; c.1685A>G) change within the platelet-derived growth factor receptor beta gene (PDGFR
170 in 2 (IGFBP-2), nerve growth factor (b-NGF), platelet-derived growth factor receptor beta polypeptide
171 erved in a laser-induced model of CNV that a platelet-derived growth factor receptor beta positive (P
173 gnificantly more NIK(+) ECs and perivascular platelet-derived growth factor receptor beta(+) preFDCs,
176 structure provides a first glimpse into how platelet-derived growth factor receptor ECD, upon ligand
177 he vascular endothelial growth factor (VEGF)/platelet-derived growth factor receptor inhibitor suniti
178 cular endothelial growth factor receptor and platelet-derived growth factor receptor inhibitor, demon
181 t epicardial-derived cells expressing PDGFR (platelet-derived growth factor receptor)-alpha were isol
182 tivation by a receptor activation loop (from platelet-derived growth factor receptor, a receptor tyro
183 ced RNA of epidermal growth factor receptor, platelet-derived growth factor receptor, and c-Met.
184 ing Smad3, epidermal growth factor receptor, platelet-derived growth factor receptor, signal transduc
185 ell lines revealed co-activation of HER2 and platelet-derived growth factor receptor-alpha (PDGFRalph
186 opulation (SP) phenotype, PECAM-1 (CD31) and platelet-derived growth factor receptor-alpha (PDGFRalph
188 and flow sorted to isolate cells expressing platelet-derived growth factor receptor-alpha and exclud
189 ssion pattern, manifest in downregulation of platelet-derived growth factor receptor-alpha and recipr
190 rogenesis from precursor cells by inhibiting platelet-derived growth factor receptor-alpha cell endoc
191 to stabilize detrusor excitability involving platelet-derived growth factor receptor-alpha positive (
193 ild-type or constitutively activated PDGFRA (platelet-derived growth factor receptor-alpha) under con
194 cells coexpressing vimentin and PDGFRalpha (platelet-derived growth factor receptor-alpha), but gene
195 tyrosine kinases (RTKs) such as PDGFRalpha (platelet-derived growth factor receptor-alpha), which sh
197 alpha signaling was conditionally blocked in platelet-derived growth factor receptor-alpha-positive a
199 y, 2) connective tissue progenitor cells, 3) platelet-derived growth factor receptor-alpha-positive c
200 nd dendritic spine formation through Rabex-5/platelet-derived growth factor receptor-beta (PDGFRbeta)
202 asculature followed by release of individual platelet-derived growth factor receptor-beta mural peric
203 iated capillary mural cell pericyte, soluble platelet-derived growth factor receptor-beta(8,18), and
204 a significant decrease in the expression of platelet-derived growth factor receptor-beta, a tyrosine
205 agent targeting VEGF receptors 1, 2, and 3, platelet-derived growth factor receptor-like protein (PD
207 structure of PDGFRbeta [a full-length human platelet-derived growth factor receptor], in complex wit
208 ne kinase activity of ABL1/BCR-ABL1 and KIT, platelet-derived growth factor receptors (PDGFRs), and t
213 y model, with positive correlation to PDGFB (platelet-derived growth factor subunit B) and MMP (matri
214 SMILR was also altered by interleukin-1alpha/platelet-derived growth factor treatment, and HAS2 expre
215 proteins (four antibodies and the chemokine platelet-derived growth factor) and two monovalent prote
216 ophages, which then provide signals (such as platelet-derived growth factor) that drive beta-cell hyp
217 lated with IL (interleukin)-1alpha and PDGF (platelet-derived growth factor)-BB with SMILR knockdown
219 d non-responders including stem cell factor, platelet-derived growth factor, and interleukin-15.
220 flammatory cytokines, invade Matrigel toward platelet-derived growth factor, and resist hypoxia-induc
222 cedures, including enamel matrix derivative, platelet-derived growth factor, platelet concentrates, a
223 ine kinase ligands (epidermal growth factor, platelet-derived growth factor, vascular endothelial gro
225 rotrophic factor, fibroblast growth factors, platelet-derived growth factor-AA, vascular endothelial
226 e Boyden chamber and show that a gradient of platelet-derived growth factor-AB (PDGF-AB) expedites mi
227 sient treatment with AZA in combination with platelet-derived growth factor-AB converts primary somat
228 sed approach is shown here to work with both platelet-derived growth factor-BB (PDGF-BB) and vascular
229 lar endothelial growth factor-A (VEGF-A) and platelet-derived growth factor-BB (PDGF-BB) that were en
230 sforming growth factor-alpha (TGF-alpha) and platelet-derived growth factor-BB (PDGF-BB) were reduced
231 helial growth factor-A (VEGF-A) isoforms and platelet-derived growth factor-BB (PDGF-BB), mainly thro
232 the receptor tyrosine kinase (RTK) agonist, platelet-derived growth factor-BB (PDGF-BB)-induced p21C
233 rom the culture of fat with ROS or PGZ on i) platelet-derived growth factor-BB (PDGF-BB)-stimulated p
236 atrix derivative (EMD) and recombinant human platelet-derived growth factor-BB (rhPDGF-BB) with beta-
237 tor-2, transforming growth factor-beta1, and platelet-derived growth factor-BB at 2 weeks compared wi
238 growth factor, interleukin 6, angiopoietin, platelet-derived growth factor-BB, placental growth fact
239 matory cytokines interferon gamma, IL-1, and platelet-derived growth factor-BB, which are not produce
241 despite constituting a small fraction of the platelet-derived growth factor-beta (PDGFRbeta)(+) cell
242 nsforming growth factor-beta [TGF-beta], and platelet-derived growth factor-beta [PDGF-beta]) and blo
243 factor-D level, resulting in suppression of platelet-derived growth factor-beta activation and inhib
245 In conclusion, our results suggest that platelet-derived growth factor-D is a target of itracona
246 ortantly, itraconazole significantly reduced platelet-derived growth factor-D level, resulting in sup
247 ein oxidation within cells, and suggest that platelet-derived growth factor-dependent "redoxosomes,"
248 es insight into the vascular architecture of platelet-derived growth factor-driven glioblastoma.
254 factor], sCD40L [soluble CD40 ligand], PDGF [platelet-derived growth factor], RANTES [regulated on ac
258 atory diseases; however, the contribution of platelet-derived HMGB1 in thrombosis remains unexplored.
259 COMP) acts as a major endogenous plasma- and platelet-derived inhibitor of thrombin activity in vitro
260 In summary, a new neutrophil-activating platelet-derived lipid generated by COX-1 is presented t
261 sponse to donor-specific antibodies and that platelet-derived mediators may be markers of evolving al
264 rce microscopy (AFM) to quantify and qualify platelet-derived microparticles (PMPs), on the whole nan
266 Zeng et al. identified a mechanism by which platelet-derived microRNA-223 (miRNA-223) reverses VSMC
270 f patients with SCA and investigated whether platelet-derived molecules can induce phenotypic alterat
272 plasma dramatically increases the number of platelet-derived MPs, contaminates the extracellular miR
276 of PAI-1 demonstrate a major contribution by platelet-derived PAI-1 in the treatment of lenti-miR-30c
279 ings establish a previously unknown role for platelet-derived PDGFB, whereby it promotes and maintain
281 length found in platelets (60-100 mer), and platelet-derived polyP significantly augment the plasmin
283 bute to thrombosis in animal models, whereas platelet-derived polyphosphate (polyP) may potentiate co
284 contain polyphosphate, and the secretion of platelet-derived polyphosphate has been associated with
287 further promoting the luminal deposition of platelet-derived regulated on activation normal T cell e
288 solid tumors in humans and mice and transfer platelet-derived RNA, including miRNAs, to tumor cells i
291 that FXIa neutralized both endothelium- and platelet-derived TFPI by cleaving the protein between th
295 he naive FVIII null hemophilia A (HA) mouse, platelet-derived VIII prevents both a primary and memory
296 henne et al present data showing the role of platelet-derived von Willebrand factor (VWF) in mediatin
297 created mice with either endothelial VWF or platelet-derived VWF and examined each phenotype for ble
301 r intriguing findings were that mice lacking platelet-derived VWF, but with adequate endothelial VWF