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1 e as further nonradiative pathways come into play.

2 y and specificity were maximized at 11 years played.

3 Our study indicates that MAP1A may play a beneficial role in preserving the survival of PV(

4 Immune cells play a central role in early pregnancy establishment in

5 Living polymerizations currently play a central role in polymer chemistry.

6 zed by two invariant histidine residues that play a critical role in catalytic activity.

7 Microglia and macrophages play a critical role in choroidal neovascularization (CN

8 Electron-electron interactions play a critical role in many condensed matter phenomena,

9 Microglia play a critical role in many processes fundamental to le

10 ata and explain how periodic microstructures play a critical role in the midinfrared.

11 s have been linked to flash droughts and can play a critical role in the spread of human ignited wild

12 aptor STING (stimulator of interferon genes) play a critical role in vascular inflammation and destru

13 asively retrievable biofluids (e.g., sweat), play a critical role, because they can be deployed at a

14 enerally, and cognitive skills specifically, play a crucial role in determining economic mobility and

15 Point-of-care (POC) immunodiagnostic tests play a crucial role in enabling rapid and correct diagno

16 VGCCs are multisubunit complexes that play a crucial role in neuronal signaling.

17 uenced by cultural and social factors, which play a crucial role in the determination of handedness.

18 Swine influenza A viruses (swIAVs) can play a crucial role in the generation of new human pande

19 hermogenic fat cells (brown adipocytes) that play a crucial role in the regulation of energy metaboli

20 otein of region of difference 1, is known to play a crucial role in virulence and pathogenesis of M.

21 Sequence overlap may thereby play a determinant role in enhancer function and evoluti

22 oral hygiene measures have been suggested to play a dominant role in prevention.

23 be more common than currently known, and may play a fundamental role in age-dependent changes in repr

24 Knots play a fundamental role in the dynamics of biological an

25 Radiology departments play a fundamental role in the management of COVID-19, b

26 ms, the direct anthropogenic disturbance may play a greater role.

27 assemblies of enamel matrix proteins (EMPs) play a key role as the structural scaffolds for regulati

28 These results suggest that gaze dynamics play a key role in action selection during challenging v

29 Cytotoxic T cells play a key role in adaptive immunity by killing infected

30 d, largely transient neurons of the subplate play a key role in integrating spontaneous and sensory-d

31 eic acids like RNA and other polynucleotides play a key role in modulating protein phase separation.

32 Cells of the monocyte/macrophage lineage play a key role in providing chemokines and cytokines fo

33 Our study provides evidence that MPs play a key role in SCD pathophysiology by triggering a p

34 oestrogens need to be investigated, as they play a key role in synaptogenesis and corticogenesis dur

35 otein-coupled receptor (GPCR) kinases (GRKs) play a key role in terminating signals initiated by agon

36 actors, and in particular diet, are known to play a key role in the development of Coronary Heart Dis

37 Parvalbumin-expressing (PV+) interneurons play a key role in the maturation and synchronization of

38 erals, such as the iron sulfide mackinawite, play a key role in the remediation of uranium from groun

39 Well-characterized antibody reagents play a key role in the reproducibility of research findi

40 rticulates in subglacial environments, which play a key role in trace elemental cycles, with potentia

41 We hypothesized that IDO could play a key role to locally regulate cardiac homeostasis

42 ther hand, mucociliary clearance appeared to play a less prominent role in the clearance of those pro

43 cteria and archaea), 2 microbial groups that play a major role in the global carbon cycle.

44 Our results suggest that Ole e 7 could play a new role as primary sensitizer in regions with hi

45 ke protein homolog (PfRh) family of proteins play a pivotal role in merozoite invasion and hence are

46 nterrogations demonstrate that these neurons play a pivotal role in the regulation of thirst stimulat

47 rmational fluctuations in a scaffold protein play a positive role in recruiting downstream signaling

48 lper T cells, which produced IL-10 and could play a prominent pathogenic role in SLE.

49 y target proteins and have been suggested to play a role in carcinogenesis.

50 nrichment cultures, indicating that they may play a role in dechlorination of the PCDDs.

51 ent observations indicate that LLPS may also play a role in disease.

52 pporting our conclusion that these responses play a role in driving early HIV-1 viral evolution.IMPOR

53 atus of the tumor and HBOC O(2) affinity may play a role in increased O(2) delivery to the tumor.

54 hat dysregulation of the AHR/CYP1A1 axis may play a role in inflammatory skin disease.

55 opsins and phototransduction genes known to play a role in light detection in most animals.

56 ants, it is not clear if palindromic repeats play a role in maintaining sequence conservation in the

57 d cells, suggesting that tubulin binding may play a role in MEKK1 activity at the cellular periphery.

58 n RNA-binding protein that has been known to play a role in osmoregulation in proteobacteria.

59 NES shows that genetic factors are likely to play a role in PNES or its comorbidities in a subset of

60 monstrate that ADHD and schizophrenia likely play a role in the aetiology of self-harm using multivar

61 al friction of disulfide-reduced mSOD1 might play a role in the amyotrophic lateral sclerosis-linked

62 dent dephosphorylation of the alpha2 subunit play a role in the dynamic regulation of GABA(A)R accumu

63 modifications are increasingly recognized to play a role in the etiology and pathophysiology of schiz

64 bloom dominant species and other taxa could play a role in the interplay of microbial community and

65 e resulting enhancement in proteome flux may play a role in the survival of N2a cells upon prion infe

66 and as in mammals - olfactory receptors may play a role, providing new insights into the development

67 atidic acid (PA), which has been proposed to play a second messenger role in immunity.

68 pact, evidence suggests that genetic factors play a significant role in completed suicide.

69 n the oral cavity, and although they may not play a significant role in microbiome communities, they

70 n mouse lymphatic smooth muscle, they do not play a significant role in modulating the frequency of t

71 egetation cover and water body availability, play a significant role in modulating the probability of

72 and miR-155, suggested that microRNAs might play a significant role in regulation of PRF expression.

73 Selective sweeps are thought to play a significant role in shaping patterns of variabili

74 m (Hathewaya histolytica) collagenase (ColH) play a significant role in the infection process and the

75 Predictability thus appears to play a similar role in non-verbal comprehension of seque

76 as trivalent ytterbium ions (Yb(3+) ), have played a central role in the first demonstrations and su

77 The Akt/mTOR pathway played a critical role in the AML-EV-induced phenotypica

78 In the Afrotropics, megaherbivores have played a key role before their recent decline.

79 n, these selective shifts are likely to have played a significant role in the emergence of human-spec

80 pallidal (SP) medium spiny neurons (MSNs) as playing a key role.

81 These findings highlight the hippocampus playing a multifaceted role in socially adaptive learnin

82 are upregulated under FR light supports MAAs playing a role in photon dissipation and thermoregulatio

83 Previous heat exposure plays a beneficial role in modifying the exaggeration of

84 These results suggest that the vmPFC plays a causal role in the acquisition of new learning a

85 mice, suggesting that chromophore deficiency plays a causative role in visual defects in early DR.

86 Synaptic dysfunction plays a central role in Alzheimer's disease (AD), since

87 e metabolic dysfunction, including fibrosis, plays a central role in DM pathogenesis.

88 sing theories, such reversed processing also plays a central role in later stages of perception.

89 ortant for hematopoietic differentiation and plays a central role in malignant disease.

90 Results show the capsid protein plays a central role in the flavivirus assembly process.

91 ear receptor small heterodimer partner (Shp) plays a complex role in lipid metabolism and inflammatio

92 ned whether the content of response feedback plays a critical role for the acquisition and long-term

93 growth factor and pro-inflammatory cytokine, plays a critical role in alveolar macrophage homeostasis

94 MAF1 is a phosphoprotein that plays a critical role in cell growth control as the cent

95 It is now apparent that p53 plays a critical role in controlling immune recognition

96 Immune microenvironment plays a critical role in lung cancer control versus prog

97 thin layer of soil surrounding plant roots, plays a critical role in plant's adaptation to the envir

98 hat coats all non-keratinized epithelia, and plays a critical role in protecting the human body from

99 DNA methylation plays a critical role in regulating gene expression, gen

100 overproduction of urates and renal function plays a critical role in serum uric acid levels.

101 Here, we report that CD2 costimulation plays a critical role in target cell killing by freshly

102 ozone-depleting agent, nitrous oxide (N(2)O) plays a critical role in the global climate.

103 ppocampal neurons, we show here that tamalin plays a critical role in the ligand-dependent internaliz

104 ptibility and reinforces the concept that RA plays a critical role in the pathophysiology of arrhythm

105 Hence, Dot1l plays a critical role in the thermogenic program and may

106 at what stages of differentiation autophagy plays a critical role.

107 l stromal cells at the time of implantation, plays a crucial role during early pregnancy.

108 ontent, indicating that evolutionary history plays a crucial role in determining an organism's compos

109 Magnetotail reconnection plays a crucial role in explosive energy conversion in g

110 Mounting evidence indicates that SUMOylation plays a crucial role in maintaining and regulating neura

111 This process plays a crucial role in organ development and repair, in

112 ase (LPL) is active in capillaries, where it plays a crucial role in preventing dyslipidemia by hydro

113 KIF5B plays a dominant role, whereas KIF13B helps Rab6 vesicle

114 Snow plays a fundamental role in global water resources, clim

115 Theory of mind plays a fundamental role in human social interactions.

116 aks a protective barrier, temporarily, which plays a fundamental role in maintaining a homeostatic en

117 Crucially, calcium plays a fundamental role in stabilizing cbEGF domains.

118 linker-mediated vitrimers, in which entropy plays a governing role.

119 Runx1 is a transcription factor that plays a key role in determining the proliferative and di

120 ization of chromatin inside the cell nucleus plays a key role in gene regulation and genome replicati

121 at glycogen-synthase kinase 3beta (GSK3beta) plays a key role in memory formation, yet its role in mo

122 cate cascade of the innate immune system and plays a key role in microbial defense, inflammation, org

123 essing.SIGNIFICANCE STATEMENT The cerebellum plays a key role in motor control and motor learning.

124 Although regulation of the epigenome plays a key role in shaping stem cell hierarchies, diffe

125 diverse repertoire of T-cell receptors (TCR) plays a key role in the adaptive immune response to infe

126 The linker in a drug conjugate plays a key role in the circulation time of the conjugat

127 Overall, these data reveal that S100A6 plays a key role in the PPP5C-FKBP51 axis to inhibit I(S

128 re, we demonstrate that exonuclease 1 (EXO1) plays a key role in the resolution of, and replication t

129 Tau is a microtubule-associated protein that plays a major role in Alzheimer's disease (AD) and other

130 etic exchange between homologous chromosomes plays a major role in evolution by breaking linkage betw

131 emonstrate that the source of IL6 production plays a major role in the physiological regulation of me

132 Nipah virus (NiV) matrix protein (NiV M) plays a major role in virus assembly.

133 Whether NGAL plays a mechanistic role in ANCA-associated vasculitis i

134 pment and suggests that autophagy in general plays a much more prominent role during brain developmen

135 The HLA system plays a pivotal role in both clinical applications and i

136 tion mouse model, the data reveals that TET2 plays a pivotal role in mammary gland development and lu

137 Acetylcholine in the striatum plays a pivotal role in such adaptation, and its release

138 Our findings also demonstrate that RUNX3 plays a pivotal role in the inhibition of apoptosis foun

139 Transforming growth factor-beta1 (TGF-beta1) plays a premier role in fibrosis.

140 clude, our findings show that system x(c)(-) plays a previously unrecognized role in regulating corti

141 It has been recently shown that Wnt plays a priming role for ISC self-renewal by inducing RS

142 nst ZIKV by serving as a decoy receptor, and plays a protective role in ZIKV-mediated brain injuries.

143 any studies have suggested that dynamin also plays a regulatory role during the early stages of CME;

144 Finally, Crb1 plays a role in cones' responsiveness to light through a

145 allow us to propose that the pyridone ligand plays a role in enhancing the rate- and enantio-determin

146 pellicle (PSP), respectively, whereas csdEF plays a role in galactosylation of lipoteichoic acid (LT

147 understanding of this structure, and how it plays a role in governing mechanical and other physical

148 ver, its cellular function(s) and whether it plays a role in maintenance of genome stability remain t

149 ng PTSD; highlighting that sleep potentially plays a role in PTSD's pathology.

150 teracts with PBP1b and that this interaction plays a role in the activation of its GTase activity by

151 The tumor microenvironment (TME) plays a significant role in cancer progression and thus

152 zo[2,1,3]thiadiazole S-N-containing moieties plays a significant role in governing the molecular geom

153 (GRD, Platanista gangetica gangetica), which plays a significant role in maintaining the structure, f

154 activation of the primary motor cortex (M1) plays a significant role in mediating its therapeutic ef

155 sis studies reveal that the region D1 in p27 plays a significant role in mediating the association ki

156 Actin-membrane release plays a similar role in protrusions driven by intracellu

157 Several studies have suggested that NO plays a vast and diverse signaling role in molds.

158 The BLM helicase protein plays a vital role in DNA replication and the maintenanc

159 Fish freshness plays a vital role in the fish industry and also affects

160 ch clearly suggests that these heme proteins play additional roles unrelated to nitrogen fixation.

161 indicate that ILM macrophage cells appear to play an early and regionally specific role of nerve fibe

162 Nanomaterials can play an essential role in bacterial sensing owing to the

163 ) is a circulating cytokine that is known to play an essential role in the endothelial homeostasis an

164 l energy transport and thermal effects could play an explicit role even if the charge transfer is inh

165 Conceptual replications play an important but separate role in validating theori

166 ARS-CoV-2 evolution, and therefore, ISMs can play an important complementary role to phylogenetic tre

167 e stragglers(4) and rapid rotators(5)), they play an important part in our interpretation of stellar

168 evant sensory regions have been suggested to play an important role for both mechanisms.

169 eristics and physiological differences could play an important role governing their distribution patt

170 cted optical magnetic field can nevertheless play an important role in a class of optical nonlinearit

171 B cells play an important role in allergies through secretion of

172 Nurses can play an important role in assisting the delivery of orop

173 They play an important role in blood pressure regulation and

174 Primary mechanosensory neurons play an important role in converting mechanical forces i

175 al tubule YAP-dependent paracrine mechanisms play an important role in diabetic interstitial fibrogen

176 anosines in the 5' untranslated region (UTR) play an important role in Gag:RNA interactions leading t

177 Endothelial cells play an important role in maintenance of the vascular sy

178 ing complex/cyclosome (APC/C) is reported to play an important role in metaphase-to-anaphase transiti

179 drought- and heat-stressed plants that might play an important role in non-canonical poly(A) site cho

180 Social networks play an important role in population processes such as t

181 This coupling may play an important role in preventing the backflow of rea

182 CoV-2 is microbiological, imaging techniques play an important role in supporting the diagnosis, grad

183 For these fungi, helper bacteria play an important role in the establishment of plant-fun

184 Aberrant methylated genes (DMGs) play an important role in the etiology and pathogenesis

185 d its autoamplification of IL-33/ST2 pathway play an important role in the induction of asthma-like p

186 While magnetic fluctuations play an important role in the materials' unusual electro

187 as specialized proresolving mediators (SPMs) play an important role in the restorative response.

188 olymerization methods are reviewed, as these play an important role in the wide range of applications

189 o- and eukaryotes, including humans, and may play an important role in transcription-coupled homologo

190 art function, respectively, in-silico models play an important role.

191 inase interactor 1 (GIT1), which we found to play an unexpected stimulatory role in GPCR-mediated eNO

192 We conclude that, in early plants, H3K27me3 played an essential role in heterochromatin function, su

193 biological and medical applications and are playing an increasingly important role in the nascent fi

194 Based on current evidence, imaging plays an ancillary role in the management of those with

195 cooling load, and that near-surface humidity plays an equally important role.

196 a striking capability of the auditory system-plays an essential role in animals' survival (e.g., dete

197 Collectively, our data show that Sema3E plays an essential role in dampening the early inflammat

198 antiporter that belongs to SLC30 family and plays an essential role in regulating Zn(2+) accumulatio

199 Irrigation plays an essential role in sustaining crop production in

200 The thymus is a primary lymphoid organ that plays an essential role in T lymphocyte maturation and s

201 We report here that the bacterial sRNA SsrA plays an essential role in the light-organ symbiosis bet

202 The Insulin/IGF-1 signalling (IIS) pathway plays an essential role in the regulation of glucose and

203 ndings indicate that dynamic RNA methylation plays an important regulatory role in oligodendrocyte de

204 Roundabout guidance receptor 2 (ROBO2) plays an important role during early kidney development.

205 Inflammation plays an important role in cardiovascular disease (CVD)

206 link between oxidative stress and autophagy plays an important role in cellular responses to a wide

207 Activation of dinitrogen plays an important role in daily anthropogenic life, and

208 in tumor cells and its interaction with PD-1 plays an important role in evading immune surveillance;

209 provide the first direct evidence that BP180 plays an important role in granulopoiesis through regula

210 or the generation of IBs, indicating that it plays an important role in IB formation during infection

211 Hippocampal neurogenesis plays an important role in learning and memory function

212 Autophagy plays an important role in myogenesis, but the asynchron

213 In vivo studies uncover that EhActn2 plays an important role in phagocytic cup formation and

214 Ube2v1 plays an important role in protein aggregate formation,

215 This astroglial mechanism plays an important role in the autonomic control of hear

216 Our data suggest that ToxR plays an important role in the resistance to reactive ox

217 evelopment, the Notch ligand JAGGED 1 (JAG1) plays an important role in the specification of the pros

218 We conclude that MEGF11 plays an important role in tumour survival and that over

219 Yet color plays an important role in visual processing when it com

220 kocytes persist within kidney transplants or play any role in rejection is unknown, however, in part

221 nd functional assays to investigate the role played by conformational heterogeneity in determining th

222 Our results enlighten the role played by CSA and CSB as part of a ubiquitin/proteasome

223 n order to better elucidate the complex role played by CYP2J2 in cardiac cells, we performed targeted

224 However, the specific role played by each ligand has been unclear.

225 We show the vital role played by mountains acting simultaneously as cradles and

226 he atherothrombosis, where a pivotal role is played by platelet activation, it would be arguable that

227 gs demonstrate that (1a) hippocampus and PFC play complementary roles in the implicit, unconscious le

228 Instead, the opioid peptides play complex and overlapping roles in a variety of syste

229 unexpanded CGG repeats and their translation play conserved roles in regulating fragile X protein (FM

230 amily of functional human microproteins that play critical and diverse cellular roles.

231 r 70 putative SNX-BAR ligands, many of which play critical roles in apoptosis, cell adhesion, signal

232 studies of some native-like nucleosomes that play critical roles in chromatin functions.

233 d biological stresses, support biofilms, and play critical roles in interactions between bacteria and

234 CBP acetylate histone lysine side chains and play critical roles in regulating gene transcription.

235 Src family kinase Lck plays critical roles during T cell development and activ

236 ator of biochemical signaling in neurons and plays critical roles in neuronal function.

237 The immune system plays critical roles in promoting tissue repair during r

238 HSI2- and HSL1-dependent histone methylation plays critical roles in regulation of seed dormancy duri

239 The oxytocin receptor (OTR) plays critical roles in social behavior development.

240 Consequently, EPKs play crucial roles in cell differentiation and cell-cycl

241 ients, we hypothesize that ET(A)R and ET(B)R play dichotomous roles in oral carcinogenesis and pain,

242 hether the SNPs in different genomic regions play different roles in trait heritability and which reg

243 Typically, edges with different DD play different structural roles and the DD distribution

244 that alpha2delta1 and alpha2delta3 subunits play distinct but complementary roles in driving formati

245 Moreover, direct and indirect pathways also play distinct roles in timing.

246 sights on the roles that specific cell types play during norovirus pathogenesis.

247 tion the underlying processes that may be at play during the earliest AD-related immune response.

248 They can play either beneficial or detrimental roles in lesion pa

249 dependent cell-cell adhesion proteins, which play essential roles in animal evolution, tissue develop

250 Cell-ECM (extracellular matrix) interactions play essential roles in the morphogenesis of PAAs and th

251 Lipids are basic cellular constituents playing essential functions in energy storage and the ce

252 Although APE2 plays essential roles in base excision repair and ATR-Ch

253 Interlayer coupling plays essential roles in the quantum transport, polarito

254 Species-fair comparisons level the playing field between natural and artificial intelligenc

255 Play fighting network centrality was quantified using me

256 The benefits of play fighting were therefore limited to specific aggress

257 lfur-based ligands are versatile donors that play important roles in a wide array of subdisciplines o

258 They play important roles in acidification of intracellular v

259 a wide range of extracellular proteins that play important roles in bacterial viability and in inter

260 CCA) and their associated microbial biofilms play important roles in determining the settlement locat

261 ggesting that the structural differences may play important roles in disease.

262 Small RNAs (sRNAs) regulate gene expression, play important roles in epigenetic pathways, and are hyp

263 Health organizations can play important roles in facilitating these partnerships.

264 Type 1 cGMP-dependent protein kinases (PKGs) play important roles in human cardiovascular physiology,

265 Epigenetic modifications on chromatin play important roles in regulating gene expression.

266 sal anterior cingulate cortex and insula may play important roles in switching between these VPFC and

267 pology, and building block stoichiometry all play important roles in the efficacy of the ionophoric a

268 Small RNAs are non-coding RNAs that play important roles in the lives of both animals and pl

269 MDSCs are known to play important roles in tumor immune evasion.

270 teins (RBPs) are a large protein family that plays important roles at almost all levels of gene regul

271 Endoreplication plays important roles in both normal plant development a

272 ronal and glial progenitors and mature cells play in CNS angiogenesis and neurovascular barrier matur

273 regarding the role that sensorimotor regions play in conceptual processing, with embodied theories su

274 cause of the central role that light regimes play in determining the timing of biological activity.

275 ole that mutually beneficial behaviors might play in facilitating and stabilizing social systems.

276 uld be given more credit for the role it can play in stabilizing future global climate.

277 n-like proteins (UBLs)-Atg5, Atg12, and Atg8-play in the formation of the double-membrane vesicle aut

278 t virus-derived endogenous elements may have played in the evolution of bat immunity is poorly unders

279 ) shed light into the role genetic variation plays in control of ground state pluripotency.

280 d reveals the key role that polar ice volume plays in the predictability of Cenozoic climate dynamics

281 However, the endogenous role that PC2 plays in the regulation of general cellular homeostasis

282 TRIM family proteins play integral roles in the innate immune response to vir

283 Receptor-like protein kinases (RLKs) play key roles in regulating plant growth, development a

284 an body, encodes TTN (titin), a protein that plays key structural, developmental, and regulatory role

285 Living in various habitats, tardigrades play major roles as consumers and decomposers in the tro

286 DNA is a widespread modification of DNA that plays numerous critical roles.

287 Moreover, autophagy can play opposing roles in the tumor microenvironment via no

288 Fibroblast growth factor (FGF) signaling plays pivotal roles in generating and maintaining NPCs d

289 ases suggests that redox modifications could play prominent roles in regulating mitotic processes.

290 t not in humans), is potently obesogenic and plays putative roles governing certain evolutionary beha

291 CCCs play roles in cellular volume regulation, neural develop

292 ied VA-binding region contains residues that play roles in the mechanisms by which heat, mechanical s

293 e new structural and functional domains that play roles in UAF complex integrity, assembly, and biolo

294 derived growth factor receptor (PDGFR)-alpha plays roles in cell survival, proliferation, and differe

295 4, the prototype of PC4-like proteins, which plays roles in transcription and maintenance of genome s

296 et activity-independent processes might also play some part.

297 These results suggest that Notch ligands play specific roles in the adult pancreas and highlight

298 efficients that drive those systems actually play the role of the corresponding Lagrange multipliers.

299 largest and most diverse phylum on Earth and play vital roles in nearly every ecosystem.

300 o our expectations we found that spontaneous play was suppressed in the high-milk calves housed in mi