ライフサイエンスコーパス: pleasure

1 nnabinoid/orexin signals can amplify sensory pleasure).

2 s conveying more positive emotions (calm and pleasure).

3 ression and regulation of emotion and evokes pleasure.

4 the expectation is reduced pain or increased pleasure.

5 on is strongly influenced by expectations of pleasure.

6 continued use of drugs that no longer bring pleasure.

7 reason given for taking alcohol or drugs was pleasure.

8 r, such as eating to cope with hunger or for pleasure.

9 der is anhedonia, an inability to experience pleasure.

10 socorticolimbic activity unique to states of pleasure.

11 higher-order cortical areas in music-induced pleasure.

12 d anhedonia, a reduced ability to experience pleasure.

13 acceptability due to its role in consumers' pleasure.

14 research to encompass positive outcomes and pleasure.

15 e of the dopaminergic system in music-evoked pleasure.

16 y of thinking about the paradox of aesthetic pleasure.

17 osely tied to challenge and interest than to pleasure.

18 icle for transforming negative emotions into pleasure.

19 urable stimuli or the capacity to experience pleasure.

20 its positive feedback reinforcement through pleasure.

21 Music ranks among the greatest human pleasures.

22 g music reliably ranks among life's greatest pleasures.

23 The attributes identified were (1) simple pleasure, (2) prioritising relationships, (3) living eac

24 The time course of pleasure, across stimuli, is well-fit by a model with on

25 nerally considered an independent measure of pleasure, activated brain regions involved in reward cir

26 sort into three social-functional subtypes: pleasure, affiliative, and dominance.

27 mesolimbic dopamine system, may not generate pleasure after all.

28 Pleasure amplitude increases linearly with the feeling o

29 well-fit by a model with one free parameter: pleasure amplitude.

30 Drugs causing pleasure and addiction are comparatively recent and like

31 , but they instill in the viewer aesthetical pleasure and admiration for their creators.

32 these chemical senses cannot only reduce the pleasure and comfort from food, but represent risk facto

33 tioning and satisfaction, including improved pleasure and communication during sex, satisfaction with

34 However, in humans tickling induces both pleasure and displeasure, and neither an established non

35 We discuss the emerging science of pleasure and flourishing, insights into the brain mechan

36 urrent neurocognitive models of music-evoked pleasure and highlight the synergistic interplay between

37 Food additives enhance sensory pleasure and improve marketability in food product formu

38 y shows a causal role of dopamine in musical pleasure and indicates that dopaminergic transmission mi

39 The Roman poet Horace said poetry gives pleasure and instructs.

40 rm for exploring the sensory basis of sexual pleasure and its relationship to affective touch.

41 n induced the greatest reports of subjective pleasure and led to the greatest deactivation of the def

42 enhanced subjective reports of music-induced pleasure and motivation, whereas inhibition of the same

43 ctively, subjective reports of music-induced pleasure and motivation.

44 d to opposite effects in measures of musical pleasure and motivation: while the dopamine precursor le

45 g, which is the consumption of food just for pleasure and not homeostatic need, is a suitable paradig

46 epidemiology that incorporates the study of pleasure and other positive features alongside sexually

47 Yet epidemiologic research into sexual pleasure and other positive sexual outcomes has been sca

48 ago, as young graduate students, we had the pleasure and privilege of being in Joan Steitz's laborat

49 The nucleus accumbens (the pleasure and reward 'hub' in the brain) influences wheel

50 a may contribute to subjective experience of pleasure and reward during intoxication.

51 cluding greater attention to the dynamics of pleasure and reward in sexual health promotion.

52 accumbens, a brain region thought to mediate pleasure and reward that could also contribute to the an

53 pting the function of this critical locus of pleasure and reward.

54 that emphasize limbic-regulated responses to pleasure and reward.

55 to help postmenopausal women maximize sexual pleasure and satisfaction.

56 d from stimuli that otherwise produce strong pleasure and spares that of less-pleasant stimuli.

57 : (a) the traditional hedonic view that drug pleasure and subsequent unpleasant withdrawal symptoms a

58 t cause enhanced "liking" reactions to sweet pleasure and that stimulate food intake.

59 f environmental stress to anhedonia (loss of pleasure and/or motivation).

60 The pleasures and satisfactions of teaching, writing, and sa

61 or emotion (implicit 'liking' and conscious pleasure) and (3) motivation (implicit incentive salienc

62 th (depression), hedonic (life satisfaction, pleasure) and eudaimonic (self-realization) well-being,

63 ch, and includes items assessing motivation, pleasure, and emotion expression.

64 humor appreciation (e.g., reward processing, pleasure, and enjoyment).

65 ritical for the initiation and regulation of pleasure, and human neuroimaging studies exhibit some tr

66 symptomatology (including pessimism, loss of pleasure, and loss of interest in previously enjoyed act

67 m measures, self-report scales of sociality, pleasure, and motivation, and coded facial expressions.

68 f one's subjective experiences of intensity, pleasure, and pain.

69 emonstrate their positive effects on stress, pleasure, and social cognition.

70 iding ecosystem services, natural beauty and pleasure, and sustaining human lives is a message that r

71 and reward systems is important for musical pleasure, and that individual differences in the structu

72 the strongest drivers of food consumption is pleasure, and with a large variety of palatable food con

73 Loss of the capacity to experience pleasure (anhedonia) is a core clinical feature of schiz

74 Minimizing pain and maximizing pleasure are conflicting motivations when pain and rewar

75 Subjective feelings of 'pleasure' are differentially driven by expectations of p

76 Users report heightened sexual pleasure as a motivation for further drug use and displa

77 de sexual health, sexual justice, and sexual pleasure as one of four pillars of public health enquiry

78 id release even in the absence of subjective pleasure associated with feeding, suggesting that metabo

79 n sum, we confirm Kant's claim that only the pleasure associated with feeling beauty requires thought

80 icate that this dopaminergic system mediates pleasure associated with music; specifically, reward val

81 enfreude; displeasure at others' fortune and pleasure at others' misfortune, respectively).

82 happiness and defines well-being in terms of pleasure attainment and pain avoidance; and the eudaimon

83 The experience of beauty is a pleasure, but common sense and philosophy suggest that f

84 ents contribute to the perception of tactile pleasure, but the brain areas involved in their processi

85 e argue that the fluency theory of aesthetic pleasure can be amended to meet the requirements of the

86 ng beauty requires thought but that sensuous pleasure can be enjoyed without thought and cannot be be

87 thought and disprove his claim that sensuous pleasures cannot be beautiful.

88 Recent research suggests that musical pleasure comes from positive reward prediction errors, w

89 state, personality traits, pain or physical pleasure, deception, and even social status.

90 e both motivation for social contact and the pleasure derived from interacting socially.

91 om negative social interactions and decrease pleasure derived from positive interactions.

92 and recreational exercise is the motivating pleasure derived from prolonged physical activity, which

93 Hedonic feeding is driven by the "pleasure" derived from consuming palatable food and occu

94 t and fiction is distinct from the immediate pleasure deriving from sensory features, because it requ

95 ted plasma proteins with the "motivation and pleasure" dimension and cognition.

96 ssivity, negative symptoms of motivation and pleasure, disorganized symptoms, and current cognitive a

97 stimulus to a greater degree, and felt more pleasure during the experience.

98 Overindulgence in harmless bodily pleasures (e.g., masturbation, gluttony) is perceived as

99 s for pleasure generators, including classic pleasure electrodes and the mesolimbic dopamine system,

100 maging studies have shown that music-induced pleasure engages cortico-striatal circuits involved in t

101 maging studies have shown that music-induced pleasure engages cortico-striatal circuits related to th

102 f these symptoms, deficits in motivation and pleasure, especially in the domain of avolition, are par

103 eported more improvement over time in sexual pleasure (EST1 = .32 and EST2 = .62; P = .001), less dis

104 ia reflects a reduced capacity to experience pleasure, evidence is mixed as to whether anhedonia is c

105 What contributes to the pleasure evoked by flavors?

106 amplified reward-relevant reactivity toward pleasure-evoking stimuli also.

107 olimbic reward brain networks in response to pleasure-evoking stimuli.

108 is unclear if this temporal dissociation of pleasure experience is also relevant in other symptoms l

109 e distraction greatly reduces the beauty and pleasure experienced from stimuli that otherwise produce

110 is thought to underlie motivated behaviour, pleasure experiences and emotional expression based on a

111 of sexual expression and the penalisation of pleasure faced by people with HIV.

112 Here, participants continuously rated the pleasure felt from a nominally beautiful or non-beautifu

113 usic is one of the most important sources of pleasure for many people, but at the same time there are

114 e pavlovian-triggered motivation and sensory pleasure for the same reward within the same participant

115 acebo, ketamine increased ratings of feeling pleasure from being with family or close friends, seeing

116 atum in motivation to smoke, anticipation of pleasure from cigarettes and relief of withdrawal sympto

117 consumers were deprived of satisfaction and pleasure from foods, experienced difficulties finding sa

118 tal hyposensitivity and experience no direct pleasure from gentle touch or vibration.

119 sure from social situations, such as feeling pleasure from helping others.

120 Humans can anticipate music and derive pleasure from it.

121 Some healthy people fail to derive pleasure from music despite otherwise preserved perceptu

122 Pleasure from social situations was assessed in a sample

123 mine treatment was associated with increased pleasure from social situations, such as feeling pleasur

124 It allows us to organize, understand, derive pleasure from, and remember music.

125 ), and evidence for the causal generation of pleasure (gained largely from brain manipulation studies

126 me of the best known textbook candidates for pleasure generators, including classic pleasure electrod

127 Music's ability to induce feelings of pleasure has been the subject of intense neuroscientific

128 Whether changes in musical expectancy elicit pleasure has thus remained elusive [11].

129 ng alcohol-induced sedation, stimulation, or pleasure (i.e., feeling, liking).

130 Stress reduction, pleasure, improved cognition and other central nervous s

131 stimuli, correlating with decreased interest/pleasure in and performance of activities.

132 donia, a pronounced reduction in interest or pleasure in any of life's daily activities, is a cardina

133 those that are high in fat and sugar, evoke pleasure in both humans and animals(1).

134 d clinically as a deficit in the interest or pleasure in daily activities.

135 ese findings provide evidence for a basis of pleasure in humans that is distributed across brain syst

136 ack of appetite (58.1%, n = 72), and lack of pleasure in life (53.2%, n = 66) were the most commonly

137 We propose that pleasure in music arises from interactions between corti

138 d its involvement in reward, motivation, and pleasure in other domains.

139 ntial deficit or a diminished "capacity" for pleasure in patients with schizophrenia.

140 rsistent depressed mood, loss of interest or pleasure in previously enjoyable activities, recurrent t

141 Anhedonia, or diminished interest or pleasure in rewarding activities, characterizes depressi

142 ncy toward one another in that we often take pleasure in seeing others succeed.

143 review evidence for neural representation of pleasure in the brain (gained largely from neuroimaging

144 While I take pleasure in the former, the overall contribution of the

145 ay] that they had depressed mood and lack of pleasure in usual activities in the past 2 weeks; respon

146 -denial of food as well as most comforts and pleasures in life.

147 refrontal cortex is critical for mediating a pleasure-induced down-regulation of avoidance responses

148 Pleasure is a fundamental driver of human behaviour, yet

149 We also find that strong pleasure is always beautiful, whether produced reliably

150 sm is a psychiatric disorder in which sexual pleasure is derived from inflicting pain, suffering, or

151 Pleasure is mediated by well-developed mesocorticolimbic

152 ychology to explain experiences of aesthetic pleasure is problematic because it is founded on a mecha

153 uations, the capacity to seek and experience pleasure is reduced, food intake is diminished and sexua

154 It has been suggested that pleasure is related to salience (behavioral relevance),

155 Current models suggest that musical pleasure is tied to the intrinsic reward of learning, as

156 nhedonia, or markedly diminished interest or pleasure, is a hallmark symptom of major depression, sch

157 edonia, the diminished ability to experience pleasure, is an important dimensional entity linked to d

158 Liking, or pleasure itself, is generated by a smaller set of hedoni

159 resulted in significant enhanced arousal and pleasure level compared to control.

160 es, we found a significant association among pleasure level, Stroop interference reaction time, and t

161 Pleasure 'liking' is especially generated by restricted

162 Pleasure/liking seems to be the phenomenological express

163 tested between hsCRP and the motivation and pleasure (MAP) and expressivity (EXP) dimensions of the

164 ng studies have shown that musically induced pleasure may arise from the interaction between auditory

165 Whereas easily comprehended art may elicit pleasure, meaningfulness is more closely tied to challen

166 These emerging insights into brain pleasure mechanisms may eventually facilitate better tre

167 more than merely the products of accumulated pleasure memories-even a repulsive learned cue for unple

168 ctions, including those processing affective/pleasure/motivational, nociception, and mating-specific

169 ales: expression (four items) and motivation/pleasure (nine items).

170 dently predicted depression (little interest/pleasure: odds ratio [OR]=6.65, P<0.001; depression: OR=

171 ls, fluid intake provides both satiation and pleasure of drinking.

172 Although the pleasure of eating is modulated by satiety and food depr

173 efrontal cortex system for signaling pain or pleasure of future prospects.

174 lsive, amygdala system for signaling pain or pleasure of immediate prospects, and a reflective, prefr

175 f harmony in popular music suggests that the pleasure of listening to music is linked to two characte

176 pleasure with formal modeling, relating the pleasure of music listening to the intrinsic reward of l

177 was helping young scientists experience the pleasure of performing creative research.

178 growing global consumer base appreciates the pleasures of coffee and chocolate and health warnings ar

179 mary endpoint was postinfusion self-reported pleasure on the four SHAPS items pertaining to social si

180 Causation of core pleasure or 'liking' reactions is much more subcorticall

181 neuroscience aims to understand how affect (pleasure or displeasure) is created by brains.

182 nt on the reader's needs, in the moment, for pleasure or distraction.

183 ral substrate of the inability to experience pleasure or engage in rewarding activities, 3) provides

184 tendency to link dopamine transmission with pleasure or hedonia, as opposed to other aspects of moti

185 Anhedonia, the loss of pleasure or interest in previously rewarding stimuli, is

186 elates-depressed mood and anhedonia (loss of pleasure or interest).

187 Anhedonia-the loss of pleasure or lack of reactivity to pleasurable stimuli-re

188 depression, has been defined as the loss of pleasure or lack of reactivity to pleasurable stimuli.

189 , meaningfulness does not necessarily entail pleasure or positive emotions.

190 processing but of an inability to experience pleasure or positive motivation.

191 ed alertness and arousal, whereas effects on pleasure or relaxation were less consistent.

192 In affective disorders, anhedonia (lack of pleasure) or dysphoria (negative affect) can result from

193 scores for frequency of sexual activity and pleasure-orgasm in the Brief index of Sexual Functioning

194 ects the theater, which has given me so much pleasure over the years: "There is a time for departure

195 productive concerns (P < .0001), less sexual pleasure (P = .003), and lower scores on the total Sexua

196 that each additional 10 hours of reading for pleasure per week at the end of a progression interval w

197 te model, the number of hours of reading for pleasure per week was not significantly associated with

198 viorally, we found that chords elicited high pleasure ratings when they deviated substantially from w

199 ns conveys a generalizable representation of pleasure regulated by opioidergic mechanisms remains unc

200 om exposures occurring during both work- and pleasure-related activities.

201 tions were: amusement, anger, disgust, fear, pleasure, relief, and sadness.

202 reactions during anticipated and experienced pleasure rely on partly different neurochemical systems,

203 Determining a sexual pleasure response in animals not amenable to neurobehavi

204 g population diets ought to consider sensory pleasure response to foods, in addition to a wide range

205 ryptamine (5-HT)] modulates mood control and pleasure response, whereas in the dSt, 5-HT regulates mo

206 predicted individuals' genre preferences and pleasure responses to real compositions, highlighting it

207 (VTA) is thought to contribute generally to pleasure, reward, and drug reinforcement and has been im

208 dicating aberrant functional connectivity of pleasure/reward and fear circuits.

209 es how the clinical and neural signatures of pleasure, salience, allostasis and withdrawal relate, bo

210 t electrophysiological relationships between pleasure, salience, allostasis and withdrawal.

211 om baseline at week 6 in the Snaith-Hamilton Pleasure Scale (SHAPS) and Beck Anxiety Inventory.

212 ies, using four items of the Snaith-Hamilton Pleasure Scale (SHAPS) at five time points over 1 week f

213 rger among participants with Snaith-Hamilton Pleasure Scale (SHAPS) score greater/equal to versus les

214 The Snaith-Hamilton Pleasure Scale (SHAPS) was administered.

215 mary outcome measure was the Snaith-Hamilton Pleasure Scale (SHAPS), and the primary contrast of inte

216 Rating Scale (MADRS) and the Snaith-Hamilton Pleasure Scale (SHAPS), respectively.

217 .08) and anhedonic symptoms (Snaith-Hamilton Pleasure Scale score change: -6.1 +/- 5.3, p < 0.001, d

218 tem Control, Autonomy, Self-realization, and Pleasure scale), and loneliness (3-item Revised Universi

219 measure of anhedonia (i.e., Snaith-Hamilton Pleasure Scale).

220 sion-17 (HAMD-17) and SHAPS (Snaith-Hamilton Pleasure Scale).

221 tem Control, Autonomy, Self-realization, and Pleasure scale; functional status, measured by activitie

222 d to orient toward hedonic activities (e.g., pleasure seeking), potentially placing them at risk for

223 Decreased pleasure-seeking (anhedonia) forms a core symptom of dep

224 ility and uncertainty, implying that musical pleasure should also reflect this equilibrium.

225 r cingulate cortex, as well as a predefined "pleasure signature." In contrast, negative expectations

226 gree to which people are able to derive such pleasure.SIGNIFICANCE STATEMENT Music is one of the most

227 disordered eating attitudes, while "price," "pleasure," "sociability," "traditional eating," "visual

228 d with higher CAINS total and motivation and pleasure subscale scores as well as lower effort expendi

229 ns were present between CAINS motivation and pleasure subscores and MCCB composite and subscale score

230 st that feeling beauty differs from sensuous pleasures such as eating or sex.

231 many societies moralize apparently harmless pleasures, such as lust, gluttony, alcohol, drugs, and e

232 of learning.SIGNIFICANCE STATEMENT Abstract pleasures, such as music, claim much of our time, energy

233 ilar circuitry is activated by quite diverse pleasures, suggesting a common neural currency shared by

234 ynecologic symptoms and diminution in sexual pleasure, survivors tended to have stronger, more positi

235 t poetry and art, in general, are less about pleasure than about exploration of emotions.

236 nia reflects a set of beliefs related to low pleasure that surface when patients are asked to report

237 ow considerable variability in the degree of pleasure they experience from music.

238 y combining participants' estimations of the pleasure they will derive from future events, with brain

239 prefrontal cortex while subjects imagine the pleasure they would derive from items belonging to two d

240 onto symptoms of anxious avoidance, loss of pleasure, threat dysregulation, and negative emotional b

241 bsequently enhances estimates of the hedonic pleasure to be derived from these same events.

242 ir of the Awards Committee it gives me great pleasure to convey my heart-felt congratulations to this

243 enced in numerous ways, ranging from sensory pleasure to elaborated ways of finding meaning.

244 ch interaction is critical for music-induced pleasure to emerge, then those individuals who do not ex

245 I have had the opportunity and pleasure to interact with the ASCI not only as an organi

246 a near ubiquitous sight in gardens, offering pleasure to many people through supplementary feeding, s

247 It has been a pleasure to watch that work take on a life of its own as

248 le anticipatory sensitivity and consummatory pleasure towards monetary incentives as the controls; bu

249 Here, we demonstrate that pleasure varies nonlinearly as a function of the listene

250 , hopelessness, loss of interest, or lack of pleasure) was present in 16.5% of subjects (95% CI, 16.0

251 d hours per week spent studying, reading for pleasure, watching television, playing video games or wo

252 dopamine function is causally related to the pleasure we experience from music.

253 DD (FH+) and anhedonia (reduced capacity for pleasure) were associated with altered white matter micr

254 opher Nagarjuna more aptly stated, "There is pleasure when an itch is scratched.

255 ed that active stroking elicits more sensory pleasure when touching others' skin than when touching o

256 of predictability and uncertainty in musical pleasure with formal modeling, relating the pleasure of

257 gest the involvement of MORs in human sexual pleasure, yet this hypothesis currently lacks in vivo su