ライフサイエンスコーパス: polarity

1 itches allowed for fast screening (3 min per polarity).

2 xternal nucleophile and to continuum solvent polarity.

3 y important roles in different forms of cell polarity.

4 in the regulation of cell shape changes and polarity.

5 action temperature or decreasing the solvent polarity.

6 )I and pyridine in three solvents of varying polarity.

7 subunit is the primary determinant of gating polarity.

8 , electrolyte composition, and environmental polarity.

9 to the axon tip, thus contributing to PIP(3) polarity.

10 ulfone bonds that are susceptible to solvent polarity.

11 ation of the energy landscape by the solvent polarity.

12 regular PS DNA central part in the opposite polarity.

13 ent mechanisms for axis-dependent conduction polarity.

14 hat shape but not numerosity is selective to polarity.

15 e in evoked Ca(2+) signals, regardless of HC polarity.

16 not readily enter, maintaining minus-end-out polarity.

17 n excitation, as well as changes in response polarity.

18 etween neighboring cells, termed tissue cell polarity.

19 e biogenesis of molecular asymmetry and cell polarity.

20 t development as well as PIN trafficking and polarity.

21 and late Six1 deletion disrupts hair-bundle polarity.

22 ion and protein-protein interaction) and DNA polarity.

23 ical in vivo characteristics, including cell polarity.

24 ects, which resulted from loss of hepatocyte polarity.

25 some as well as the basis of transcriptional polarity.

26 ass surfaces so as to match the local solute polarity.

27 alence as well, and thus a lack of dedicated polarity.

28 ies for the investigated GPL classes in both polarities.

29 nd methyl salicylate that forms ions in both polarities.

30 beneficial to simultaneously detect both ion polarities.

31 id mapping requires measurements in both ion polarities.

32 lutes across a wide range of chemistries and polarities.

33 We identified the regulator of PIN polarity 12 (repp12) mutation, which restored gravitropi

34 disperse from clusters lacking apical-basal polarity, a hallmark of advanced epithelial cancers.

35 tal of 109 loci with conserved dysregulation polarity across cancer types give insights into pan-canc

36 The polarity adaptor Bem1p also regulated the fMAPK pathway.

37 ges, in addition to variation in the solvent polarity, affect the outcome of the charge-transfer and

38 The local pattern of MT polarity along the neurite shaft has been found to diffe

39 media to an array of solutions with varying polarities and properties.

40 pore formation by using local mitochondrial polarity and a subcellular localization redistribution p

41 in aqueous solutions, owing to water's high polarity and ability to form hydrogen bonds, has severel

42 he results indicate correlation between dual polarity and acid-base property.

43 domain, thus establishing apical epithelial polarity and adherens junctions.

44 polarity and PCP proteins modulate spermatid polarity and adhesion via their effects on microtubule (

45 implicated in the establishment of neuronal polarity and axon elongation.

46 uronal cultures, and regulates both neuronal polarity and axon growth.

47 Both the establishment of neuronal polarity and axonal growth are crucial steps in the deve

48 nsport, as well as regulation of microtubule polarity and branching.

49 rbing this molecular complex alters neuronal polarity and causes strong developmental defects of the

50 ing ASPP2 peptide, prevents the loss of cell polarity and decreases the survival of H. pylori in infe

51 secrete a factor that promotes loss of cell polarity and delamination.

52 destinations and is thus essential for cell polarity and function.

53 uantity of radicals can be modulated by both polarity and heavy atom inclusion of the encapsulated gu

54 ng to the SF(5) moiety's dichotomy of strong polarity and high hydrophobicity, the unnatural amino ac

55 e that cadherin endocytosis coordinates cell polarity and migration cues through actin remodeling.

56 ukaryotic cell physiology, ranging from cell polarity and migration to cytokinesis.

57 to also obtain chemical information (such as polarity and molecular size) about NOM molecules.

58 single method has its limitation in terms of polarity and molecular weight of analyte molecules.

59 o of Plants (ROPs) are GTPases that regulate polarity and patterned wall deposition in plants.

60 (PCP) proteins, and studies have shown these polarity and PCP proteins modulate spermatid polarity an

61 re observed in sclerotome anterior/posterior polarity and peripheral nervous system development, and

62 siderable downregulation on a number of cell polarity and planar cell polarity (PCP) proteins, and st

63 Ras homology (Rho) GTPases regulate cell polarity and signal transduction pathways to control mor

64 ass spectrometry in order to investigate the polarity and size distributions of highly and poorly ion

65 be correlated to the change of binding site polarity and that a tyrosine to phenylalanine substituti

66 uch is known about how Cdc42p regulates cell polarity and the mating pathway, how Cdc42p regulates th

67 ier mechanisms for axis-dependent conduction polarity and their identifying band structure fingerprin

68 ues may act by biasing the direction of this polarity and thus the orientation of anisotropic growth.

69 of a prokaryotic gene structure (operons and polarity) and eukaryotic molecular homology (general tra

70 oral contrasts between eddies with different polarities, and provides a new perspective to recognize

71 ve organic chemicals with varying degrees of polarity, and (4) 46-compounds mixture containing all th

72 , such as cell-cell adhesion and apico-basal polarity, and acquire migratory and invasive traits.

73 /or cell proliferation, loss of apical-basal polarity, and appearance of epithelial-to-mesenchymal tr

74 gering UJT, cell-cell junctions, apico-basal polarity, and barrier function remain intact, cells elon

75 links between intercellular signaling, cell polarity, and cellular organization remain unclear.

76 rphogenic protein (BMP) gradients drive this polarity, and colorectal cancer fundamentally reflects d

77 ive imaging for mitochondrial inner membrane polarity, and immunohistochemistry.

78 epithelium brush border membrane, junctional polarity, and maturation.

79 trol pathways due to their morphology, size, polarity, and postmitotic nature.

80 molecules to partition based on their size, polarity, and specific binding motifs.

81 branch structure by specifying the position, polarity, and targeting of these events.

82 yeast, the Rho GTPase Cdc42p regulates cell polarity, and through the p21-activated kinase Ste20p, C

83 oids to leflunomide increased cell survival, polarity, and transport function.

84 y reviewing how changes in H-bonding, medium polarity, and vibrational coupling affect vibrational fr

85 Defects in cell polarity are associated with neurologic disorders includ

86 How microtubule nucleation and polarity are regulated within neurons remains unclear.

87 amic balance, levitated droplets of opposite polarity are trapped and equilibrated at fixed relative

88 difficult to separate from sediment based on polarity as a primary separation factor.

89 atterning processes make reference to global polarity axes, requiring mechanisms for axiation which,

90 dings suggest that maintaining the host cell-polarity barrier would reduce the detrimental consequenc

91 Par-3 regulates animal cell polarity by targeting the Par complex proteins Par-6 and

92 r dimers in solution where the environmental polarity can be manipulated, here, we investigate SB-CS

93 Cathode cephalad polarity caused an afferent pattern of responses (relati

94 genes important for insulin secretion, cell polarity, cell junction, cilia, cytoskeleton, vesicular

95 sduction, cytoskeletal organization and cell polarity, cell proliferation and differentiation, intrac

96 The polarity change at position T91A/V of the neutralizing a

97 ver the entire pH range, suggesting that the polarity change of the WT reflects the protonation state

98 signals on water temperature and demonstrate polarity changes in the recorded signal at temperatures

99 on with a wide range of metabolites based on polarity, charge, and allocation of important matrix int

100 modeling of the partitioning-defective (PAR) polarity complex and leads to loss of cell polarity of i

101 be tuned by external stimuli such as solvent polarity, concentration, and base treatment.

102 Furthermore, the simple polarity control strategy is extended for realizing more

103 A plasma membrane-associated polarity crescent defined by BREAKING OF ASYMMETRY IN TH

104 icrotubules and actin, respectively, and the polarity crescent is the unifying landmark that is both

105 x2 complex functions as a pheromone-promoted polarity cue in the distal pole of the cells.

106 ng must override the Rsr1-dependent internal polarity cues used for budding.

107 Wnt proteins are evolutionarily conserved polarity cues, yet Wnt mutants display variable PCP defe

108 moves to the division site based on cellular polarity cues.

109 ions, including regulation of cell shape and polarity, cytokinesis, cell migration, vesicle trafficki

110 Polarity decisions are central to many processes, includ

111 enic PREX1 expression resulted in apicobasal polarity defects and increased mammary epithelial cell p

112 ion mutants that upregulate Pyr exhibit cell polarity defects that lead to invagination defects at ga

113 enter of its degenerate motif, where A-tract polarity dictates nuances of binding.

114 und nerve potentials, we confirmed that such polarity differences in functional responses to VNS can

115 lations which indicate that polymer backbone polarity does impact the microstructure and the extent o

116 dentified strong continuity in dysregulation polarity-dominance by either up- or downregulated genes

117 gether, our analyses revealed successive and polarity-driven nuclear migrations that regulate ACD ori

118 f alkyl tail, flexibility of sterol ring and polarity due to -OH group is required to maintain high t

119 Rgd3 functions to modulate and maintain Rho3 polarity during growth.

120 light without the need to apply alternating polarity electric signals has hampered this technologica

121 Bipolar VNS trains of both polarities elicited mixed DeltaHR and DeltaBR responses.

122 ere, to identify components involved in cell polarity establishment and maintenance in plants, we per

123 Polarity establishment involves autocatalytic accumulati

124 This polarity establishment varies across cell types: in Dict

125 ct cytoskeletal networks, both guided by the polarity factor BASL, for nuclear movement before and af

126 xial domains of gene activity establishing a polarity field that orients growth.

127 combination with an orthogonal proximodistal polarity field, this system can generate diverse leaf fo

128 ve the VOC release in SC, and volatility and polarity for IC.

129 Hence, we propose a new paradigm for polarity formation: A diffusive signal triggers cell pol

130 adical in nature and resulted in a change in polarity from a polar to non-polar molecule, while for t

131 adical in nature and resulted in a change in polarity from a polar to non-polar molecule.

132 c root growth and caused a switch in PIN1-HA polarity from the basal to apical side of root epidermal

133 which allows one to estimate the apico-basal polarity from the tissue-scale modulation of cell height

134 The crumbs (crb) apical polarity genes are essential for the development and fun

135 anogaster cells with mutations in epithelial polarity genes, and wild-type cells exposed to 'super-co

136 al apicobasal polarity is controlled by many polarity genes, including the crb genes.

137 ent a varied mixture of molecular classes in polarity, glycosylation, and alkylation, manually annota

138 lipid bilayer structure is a depth-dependent polarity gradient largely resulting from the change in w

139 n stability, the effect of the water-induced polarity gradient upon backbone hydrogen bond strength h

140 roles of Scrib and Lgl1 in apical-basal cell polarity have been studied extensively, but little is kn

141 ating DB-position assignment and allows dual-polarity high-resolution MALDI-MSI and MALDI MS(2)I stud

142 has a central role in establishing neuronal polarity, how its specific organization is established a

143 n found to regulate the flagellar number and polarity; however, its role in B. burgdorferi remains un

144 Microtubule polarity in axons and dendrites defines the direction of

145 intain correct centrosome number and spindle polarity in cells.

146 This in turn creates intranuclear polarity in emerin, and thereby controls nuclear actin f

147 Reversing the polarity in molecules is a versatile tool for expanding

148 cilium with a unique assembly that regulates polarity in multiciliated cells.

149 sm for electromechanical coupling and gating polarity in non-domain-swapped K(v) channels on the basi

150 mechanistic insight into the maintenance of polarity in plants and other systems.

151 en shown to be associated with a planar cell polarity in the organisation of the actin-myosin cytoske

152 Different luminance-polarities increased N2 amplitude only, suggesting that

153 force-propagation mechanism implies that the polarity-independent sliding observed in Xenopus egg ext

154 ation, Soxhlet, etc.) and solvents (variable polarity index) were tested.

155 We used polarity-insensitive k-means clustering to segment resti

156 In many cells, polarity involves mutual antagonism between the Par comp

157 Cell polarity is a fundamental feature of all multicellular o

158 While cell polarity is an intrinsic organizer of morphogenic events

159 Epithelial apicobasal polarity is controlled by many polarity genes, including

160 l-intrinsic or -extrinsic mechanisms and how polarity is coupled to growth.

161 junctions between iono-elastomer of opposite polarity is demonstrated, which can be operated at poten

162 How apicobasal polarity is established in the developing epidermis has

163 However, it is unclear whether cell polarity is established through cell-intrinsic or -extri

164 Cell polarity is fundamental for tissue morphogenesis in mult

165 Cell polarity is fundamental to the development of both eukar

166 effect of Scrib and Lgl1 interaction on cell polarity is largely unknown.

167 bilaterians and cnidarians, epithelial cell-polarity is regulated by the interactions between Par pr

168 Tissue cell polarity is widespread in plants and can influence how c

169 , directional signaling, and implicitly cell polarity, is proposed to participate in this coordinatio

170 orm positive, negative, or even ions of both polarities, it is beneficial to simultaneously detect bo

171 We found that the Cdc42-activated polarity kinase Pak1 colocalizes with the assembling con

172 us and negative signals from the DYRK-family polarity kinase Pom1 at cell tips.

173 s a new signaling mechanism driven by a cell polarity kinase that promotes CAR assembly in the correc

174 is-associated polarization patch serves as a polarity landmark independently of all known cues.

175 etones, alcohols, fatty acids and other high polarity lipids).

176 vidual cell migration requires front-to-back polarity manifested by lamellipodial extension.

177 PIN auxin transporters are important cell polarity markers that play crucial roles in a plethora o

178 -TOF) mass spectrometry applications in dual polarity molecular imaging of biological samples, partic

179 A novel cell polarity network is uncovered comprising TKS5, FGD1, and

180 From target analysis, the effect of solvent polarity, number of linked CT entities, and excitation w

181 sly confirmed by the reversal of the voltage polarity observed under two conditions: when switching t

182 eal a clear difference in sensitivity to the polarity of an aryl C-H hydrogen bond (HB) donor for HS(

183 follows homeostatic rules that depend on the polarity of axo-axonic synapses.

184 Depletion of Spindly affects polarity of axonal microtubules in vivo and in primary n

185 od is simple and general, and the amount and polarity of charge can be flexibly tunable.

186 nfiguration, shape complexity, and luminance polarity of elements affect numerosity estimation.

187 evolution.SIGNIFICANCE STATEMENT Apicobasal polarity of epithelia is an important property that unde

188 cytokines dictating IL-17 production and the polarity of gammadelta and Th17 cells is critical.

189 ) polarity complex and leads to loss of cell polarity of infected cells.

190 10-117) suggests a significant change in the polarity of local environment in 1-palmitoyl-2-oleoyl-sn

191 ine promotes brain metastasis by skewing the polarity of M2 microglia, which enhances metastatic tumo

192 investigated the effect of biofouling on the polarity of marine plastics and estimated its potential

193 ights into the mechanism regulating the cell polarity of migrating cells by Scrib, Lgl1, and myosin I

194 ittle is known about their roles in the cell polarity of migrating cells.

195 Scrib and Lgl1 are required for proper cell polarity of migrating cells.

196 ow analysis as a new approach to analyze the polarity of MTs in the Drosophila oocyte, a cell that di

197 It is found that biofouling alters the polarity of plastics significantly; this is from (near)

198 Importantly, the polarity of ribosomes on mRNAs encoding multiple TMDs wa

199 at T4 and T5 neurons encode the location and polarity of stationary edges.

200 ly, to a supposedly unfavorable shift in the polarity of the abstracted beta-proton along the PH(2)(-

201 re missing in the majority of cilia, and the polarity of the basal bodies was disorganized.

202 Isotope effects depend upon the polarity of the bulk medium in which a chemical process

203 nor and acceptor substituents as well as the polarity of the environment.

204 surface charge to define the orientation and polarity of the nanowires.

205 d MTC spiking, regardless of the strength or polarity of the sensory response.

206 donor-guest acceptor complex, increasing the polarity of the solvent medium facilitates rare, thermal

207 w the local filament velocity depends on the polarity of the surrounding network.

208 ed whether the differences in the side-chain polarity of these AAs trigger distinct allosteric respon

209 The polarity of uncertainty representations (positive or neg

210 nopores of a host material where the lowered polarity of water enhances dissolution.

211 city of decision variables, the strength and polarity of which vary with behavioural context.

212 eport a doping-free strategy to modulate the polarity of WSe(2) transistors using same contact metal

213 two opposite charges and thus also the high polarity of zwitterions with separated charges.

214 c repair of nucleosomal DNA imposes a strand polarity on UV mutagenesis.

215 e, neural stem cells illuminated following a polarity-optimized protocol reduced the formation of amy

216 alleles that were functional for either cell polarity or nuclear cycling but not both.

217 orate counterions and that is soluble in low polarity organic solvents such as bromobenzene.

218 le but flexible actin bundles having a mixed-polarity organization, as confirmed by cryo-electron tom

219 n to nonpolar solvents, and the bulk solvent polarity parameter, E(T)(30), shows a linear free-energy

220 We here hypothesized that both the polarity pattern of MTs along the neurite shaft and the

221 are giant proteins that regulate planar cell polarity (PCP) and cell adhesion in bilaterians.

222 Planar cell polarity (PCP) and neural tube defects (NTDs) are linked

223 ivation of atypical cadherin and planar cell polarity (PCP) genes.

224 Planar cell polarity (PCP) organizes the orientation of cellular pro

225 We found that the planar cell polarity (PCP) pathway is required in alveolar epithelia

226 d for explant elongation via the planar cell polarity (PCP) pathway.

227 Planar cell polarity (PCP) proteins localize asymmetrically to instr

228 on a number of cell polarity and planar cell polarity (PCP) proteins, and studies have shown these po

229 Whether planar cell polarity (PCP) proteins, which regulate cytoskeleton dyn

230 Planar cell polarity (PCP) reflects cellular orientation within the

231 patterning of the AP axis while planar cell polarity (PCP) signaling polarizes cells with respect to

232 ecular size, shape, electronic distribution, polarity, pK(a), dipole or polarizability, which can be

233 xtent of screening being proportional to the polarity/polarizability of the solvent.

234 e results suggest a model where the cellular polarity program plays an integral role in the ability o

235 s, we analyzed the behavior of a tissue cell polarity protein BASL (BREAKING OF ASYMMETRY IN THE STOM

236 echanistic computational model that combines polarity protein biochemical interactions with vesicle t

237 through a negative regulation by the apical polarity protein Crumbs that is anisotropically localize

238 In Drosophila, the polarity protein Lethal (2) giant larvae [L(2)gl], negat

239 and signaling often via endosomal uptake of polarity proteins at tight junctions.

240 rens junction remodeling regulated by apical polarity proteins constitutes a major driving force for

241 These cell polarity proteins often exhibit coordinated patterns bet

242 spherical protoplasts, in contrast to other polarity proteins so far tested.

243 d Lethal giant larvae 1 (Lgl1) are conserved polarity proteins that play important roles in different

244 radial glia (dmNes+RG) down-regulate apical polarity proteins, including Crumbs2 (CRB2) and delamina

245 sm conserved between kingdoms and central to polarity proteins.

246 (GPCR), Tre1, to guide front-back migratory polarity radially from the cluster toward the endoderm.

247 Concurrently, multiple cell intrinsic planar polarity (referred to as iPCP) modules mediate planar po

248 analysis performed on mutant alleles of the polarity regulator crumbs, exhibiting varying rhabdomeri

249 ocalisation and levels of Lgl, a basolateral polarity regulator, in a layer autonomous as well non-au

250 aPKC, an apical polarity regulator, maintains the robustness of polarisa

251 hment involves autocatalytic accumulation of polarity regulators, including the conserved Rho-family

252 that stabilize the AIS and control neuronal polarity remain obscure.

253 , the general determinants of channel gating polarity remain poorly understood(4).

254 As protoplasts regenerate, polarity remains dynamic in isotropically growing cells

255 stabilize loops, the molecular basis of this polarity remains unclear.

256 GTPase Cdc42, but the mechanisms underlying polarity reorientation remain poorly understood.

257 rease the generality of this transformation, polarity-reversal catalysis (PRC) was successfully imple

258 Herein, we present a polarity-reversal strategy based on light-driven cobalt

259 fully open states O(1), O(2), and O(3), were polarity selective, with nonohmic conductance profiles.

260 ules could be limited because of an inherent polarity sensitivity that inhibits photochemical process

261 ptake remains a major challenge owing to the polarity, sensitivity to light, heat and solubility.

262 otrusion formation of nascent HCs and planar polarity signaling are both important for the Rock and R

263 led3 and Vangl2 is essential for planar cell polarity signaling.

264 ary epithelial cells express Wnt-Planar Cell Polarity signalling components following bile duct injur

265 quantitative characterization of spontaneous polarity site movement as a search process and use a mec

266 to probe how various processes might affect polarity site movement.

267 ast, Saccharomyces cerevisiae, relocates its polarity site when searching for mating partners.

268 ells develop a dynamic "front" (also called "polarity site") that can change direction.

269 nvolve actin-mediated vesicle traffic to the polarity site.

270 TSSE utilizes a low-polarity solvent to extract water from brine and then re

271 While relatively low polarity solvents result in partial charge transfer in t

272 ed, followed by fractionation with different polarity solvents.

273 isrupts the normal development of hepatocyte polarity, specification of cell-cell junctions, and cana

274 Neither is selective for contrast polarity, speed, or direction, highlighting key differen

275 ge, and its transition to 16 cells generates polarity such that the outer apical cells are trophectod

276 All 18 cloud-to-ground flashes were negative polarity, supportive of net negative charge within the p

277 This polarity switch is used to release payload of the polyme

278 dependently, and it is unknown whether their polarity systems are derived from a single-celled ancest

279 iphery but subsequently redistributed with a polarity that correlated with the direction of the Ca(2+

280 membrane in a gradient corresponding to cell polarity that is altered upon Rgd3 overexpression.

281 vity, which is enhanced for molecules with a polarity that is high, relative to their kinetic diamete

282 which CagA disrupts gastric epithelial cell polarity to achieve its oncogenicity is not fully unders

283 y localized to one end of a cell, allowing a polarity to be assigned to the cell.

284 reated distal lung organoids with apical-out polarity to present ACE2 on the exposed external surface

285 merase with ssDNA segments bound in opposite polarity to the N- and C-terminal domains.

286 ange factors GNOM and BIG3 in regulating PIN polarity, trafficking, and auxin-mediated development.

287 velopment, delaying the trajectory of GABA's polarity transition and altering early-life communicatio

288 unipolar regions, which can be utilized for polarity-tunable field-effect transistors and photodetec

289 by osmotic pressure increments through local polarity variations and is a more robust physicochemical

290 t physicochemical properties (boiling point, polarity, viscosity) could be exploited toward the synth

291 ensitive and ratiometric response to solvent polarity, viscosity, temperature and pressure.

292 i in the cell, where the mitochondrial local polarity was found to drastically increase.

293 tepwise increase in water ratio within lower polarity water-miscible solvents like dimethylsulfoxide,

294 n with the allowed extension in the 5'-to-3' polarity, while ScRad51 nucleation depends strongly on s

295 hus linking intercellular signaling and cell polarity with the control of oriented cell divisions dur

296 ge, outer cells acquire an apical-basal cell polarity, with expression of atypical protein kinase C (

297 Cells establish apico-basal polarity within 5 hours and a mucociliated epithelium wi

298 BASL polarity within protoplasts is dynamic and resistant to

299 ins localize asymmetrically to instruct cell polarity within the tissue plane, with defects leading t

300 nction of the two ionoelastomers of opposite polarity yields an ionic double layer, which is capable