ライフサイエンスコーパス: polyadenosine

1 ctivated caspase-7 and caspase-9 and induced polyadenosine-5'-diphosphate-ribose polymerase (PARP) cl

2 ex, bound to the 5' end of the mRNA, and the polyadenosine binding protein, bound to the 3'-terminal

3 hat may inform ongoing and future studies of polyadenosine diphosphate-ribose polymerase and PD-L1 in

4 egies, including aurora kinase A inhibitors, polyadenosine diphosphate-ribose polymerase inhibitors,

5 Polyadenosine diphosphoribose glycohydrolase (PARG) cata

6 n, we find that genes regulating stalling on polyadenosine mRNA coding for poly-Lys, a canonical RQC

7 red by the dependence of mRNA on 3'-terminal polyadenosine nucleotides (poly A) and poly A binding pr

8 RNAs involves the addition of an untemplated polyadenosine (pA) tail by the cleavage and polyadenylat

9 c cleavage of the pre-mRNA and addition of a polyadenosine (poly(A)) tail, which together define the

10 ortex embryos contains a shorter than normal polyadenosine (poly(A)) tail.

11 e RNAs differ in sequence, each ends in a 3' polyadenosine (poly(A)) tract.

12 on, and the polyadenylation step that adds a polyadenosine [poly(A)] tract to the newly generated 3'

13 s extremely AT-rich (81%) genome harbor long polyadenosine (polyA) runs within their ORFs, distinguis

14 d the parnafungins, which inhibit the enzyme polyadenosine polymerase (PAP), a key component of the m

15 l products has been identified as the fungal polyadenosine polymerase.

16 F2 protein, probably mediated in part by the polyadenosine portion of L1 RNA.

17 mechanism, causing formation and addition of polyadenosine-ribose (PAR) to acceptor proteins includin

18 3-5 of Chaetomium thermophilum Nab2 bound to polyadenosine RNA and establish the structural basis for

19 nc finger protein that binds specifically to polyadenosine RNA and is thus postulated to modulate pos

20 mediated by the common Cys(3)His zinc finger polyadenosine RNA binding domain.

21 The Drosophila polyadenosine RNA binding protein Nab2, which is ortholo

22 ated a role for the evolutionarily conserved polyadenosine RNA binding protein, Nab2, in mRNA maturat

23 of the ZC3H14 gene that encodes a conserved polyadenosine RNA binding protein.

24 Nab2 binds polyadenosine RNA primarily through a tandem repeat of C

25 The polyadenosine RNA recognition domain of Nab2 consists of

26 se coupled processes, we defined the mode of polyadenosine RNA recognition for the conserved Saccharo

27 tant Nab2 proteins with decreased binding to polyadenosine RNA show growth defects as well as defects

28 CH zinc fingers of Nab2 specifically bind to polyadenosine RNA with high affinity.

29 the ZC3H14 ortholog dNab2, which also binds polyadenosine RNA, reveals that dNab2 is essential for d

30 main, suggesting that they could all bind to polyadenosine RNA, they differ in other functionally imp

31 a gene that encodes a ubiquitously expressed polyadenosine RNA-binding protein, ZC3H14 (Zinc finger C

32 Polyadenosine RNA-binding proteins (Pabs) regulate multi

33 those found in Nab2, also specifically binds polyadenosine RNA.

34 pausing events were strongly associated with polyadenosine sequences and to a lesser degree diadenosi

35 ne binding protein, bound to the 3'-terminal polyadenosine sequences.

36 C virus (HCV) mRNA genome, lack 3'-terminal polyadenosine sequences.

37 The 3' end of clone 5K-1 contains a polyadenosine stretch preceded by a potential polyadenyl

38 nding proteins (PABPs) specifically bind the polyadenosine tail of mRNA and have been shown to be imp

39 polymerase (PAP) catalyzes the addition of a polyadenosine tail to almost all eukaryotic messenger RN

40 Frameshift mutations in the two coding polyadenosine tracks of RIZ were found in 19 (48%) of 40

41 The template polyadenosine tract is recognized in a sequence-specific

42 This effect was not seen when a 5'-polyadenosine tract was tested.

43 gene, which encodes a ubiquitously expressed polyadenosine zinc finger RNA-binding protein, is mutate