ライフサイエンスコーパス: polyadenylated

1 verified that bound mRNA remained intact and polyadenylated.

2 , are capped but, unlike host mRNAs, are not polyadenylated.

3 y cleavage by RNase P and are capped but not polyadenylated.

4 ncluding low-abundance transcripts, many not polyadenylated.

5 ense transcripts that were not capped and/or polyadenylated.

6 transcribed by RNA polymerase II but are not polyadenylated.

7 s are the only eukaryotic mRNAs that are not polyadenylated.

8 NAs are the only metazoan mRNAs that are not polyadenylated.

9 gation complexes are efficiently cleaved and polyadenylated.

10 lymerase I or III and are not believed to be polyadenylated.

11 3'UTR is unusually long and is alternatively polyadenylated.

12 adenylated intermediates than those that are polyadenylated.

13 ncreases in the number of mRNA isoforms with polyadenylated 3' ends that map to 5'-untranslated regio

14 Here we show that polyadenylated 3' termini in three yeast species (Saccha

15 ments for two yeast snoRNA genes also direct polyadenylated 3'-end formation in the context of an mRN

16 all si/miRNA-sized fragments, (ii) uncapped, polyadenylated 3-prime fragments that encode the conserv

17 g tPA is present in dendrites and is rapidly polyadenylated after glutamate stimulation.

18 sites at which precursor mRNA is cleaved and polyadenylated, allows cells to quickly respond to envir

19 ut the day, some newly synthesized rRNAs are polyadenylated and degraded in the nucleus in a robustly

20 The ASFMR1 transcript is spliced, polyadenylated and exported to the cytoplasm.

21 es and an H3 gene that encode mRNAs that are polyadenylated and expressed at 5- to 10-fold lower leve

22 anscripts produced tend to be unspliced, non-polyadenylated and expressed at levels 10 to 100-fold lo

23 from the last (most telomeric) D4Z4 unit is polyadenylated and has two introns in its 3-prime untran

24 replication-dependent histone mRNAs are not polyadenylated and instead end in a conserved stem loop

25 ess, we examined >1 billion RNA-seq reads of polyadenylated and nonpolyadenylated RNA from differenti

26 mplex is involved in the 3' end formation of polyadenylated and nonpolyadenylated RNA polymerase II t

27 bal investigation of XRN4 substrates in both polyadenylated and nonpolyadenylated RNA to better under

28 Sites of transcription of polyadenylated and nonpolyadenylated RNAs for 10 human c

29 been implicated in the transcription of both polyadenylated and nonpolyadenylated RNAs, Paf1C had not

30 ome an interleaved network of both annotated polyadenylated and nonpolyadenylated transcripts, includ

31 ep, multiple-stage reaction, where RNAs were polyadenylated and reverse-transcribed at the same time.

32 1 protein is downregulated while its mRNA is polyadenylated and stable.

33 cific RNA-seq to deeply profile lncRNAs from polyadenylated and total RNA obtained from human neocort

34 The m169 transcript is cytoplasmic, capped, polyadenylated, and interacts with miRNA-27 through seed

35 ng antisense RNA, asDOG1, that is 5' capped, polyadenylated, and relatively stable.

36 re-miRNAs) than pri-miRNAs that are cleaved, polyadenylated, and released.

37 ctor binding) and three RNA assays (nuclear, polyadenylated, and ribosome-associated).

38 howed that pc7 transcripts are expressed and polyadenylated, and that the PC7 precursor protein under

39 , to control the expression of alternatively polyadenylated antisense RNAs at the locus encoding the

40 The only eukaryotic mRNAs that are not polyadenylated are the replication-dependent histone mRN

41 es for PAP I in wild-type cells, are rapidly polyadenylated as PAP I levels increase, leading to dram

42 t of our knowledge, this description of both polyadenylated as well as nonpolyadenylated lncRNA trans

43 RNAs generated from upstream promoters were polyadenylated at (pA)p and hence not spliced.

44 RNAs polyadenylated at (pA)p2 comprise approximately 10% of B

45 ncode the viral nonstructural proteins, were polyadenylated at a high efficiency at a polyadenylation

46 d from the upstream P7 and P19 promoters are polyadenylated at a site in the central intron ((pA)p);

47 s, primarily extended through (pA)p and were polyadenylated at a site, (pA)d, located at the right en

48 ng patterns are used, and each type is found polyadenylated at either the 3' end of the genome (the d

49 stranded positive-sense RNA molecule that is polyadenylated at its 3' end and covalently linked to a

50 They were polyadenylated at multiple sites within 3 kb downstream

51 that upstream antisense RNAs are cleaved and polyadenylated at poly(A) sites (PASs) shortly after ini

52 gonucleotide prevented B19V mRNA transcripts polyadenylated at the (pA)d site during B19V infection o

53 a sufficient number of B19V mRNA transcripts polyadenylated at the distal polyadenylation site ((pA)d

54 s generated by the proximal P41 promoter are polyadenylated at the distal polyadenylation site at the

55 d version of the full-length GP mRNA that is polyadenylated at the editing site and thus lacks a stop

56 Almost all eukaryotic mRNAs must be polyadenylated at their 3' ends to function in protein s

57 RNAs encoding histones are cleaved, but not polyadenylated at their 3' ends.

58 rst report to show that the highly expressed polyadenylated BamHI A rightward transcripts (BART) vira

59 ential regulatory properties of the spliced, polyadenylated BART RNAs, a full-length cDNA clone of on

60 ptionally cleaved at a poly(A) site and then polyadenylated before being exported to the cytoplasm.

61 In metazoans, histone mRNAs are not polyadenylated but end in a conserved stem-loop.

62 istone mRNAs are the only mRNAs that are not polyadenylated but instead end in a stem-loop which has

63 -responsive gene), which is both spliced and polyadenylated but is strictly localized in nuclei.

64 sequences present in BIC RNA, a spliced and polyadenylated but non-protein-coding RNA that accumulat

65 recently that sno-lncRNAs are not capped or polyadenylated but rather are terminated on each end by

66 ammalian mRNAs because they are not normally polyadenylated but, rather, are cleaved following a 3' s

67 ication-dependent (RD)-histone mRNAs are not polyadenylated, but instead end in a stem-loop (SL) stru

68 ackaged into complete ribosomal subunits are polyadenylated by the poly(A) polymerase PAPD5 and degra

69 hat the nuclear-restricted pre-ribosomes are polyadenylated by TRAMP and degraded by the exosome.

70 The noncoding RNAs were polyadenylated, capped, and chromatin associated.

71 lated effectively in the presence of capped, polyadenylated cellular mRNAs is unknown.

72 NA metabolism events, we identify non-coding polyadenylated cis natural antisense transcripts (cis-NA

73 roteins produce mRNAs that, instead of being polyadenylated, contain a unique 3' end structure.

74 in the 3' long terminal repeat (LTR) was not polyadenylated detectably in vitro; however, if the tran

75 However, when capped and polyadenylated dicistronic RNAs were synthesized in vitr

76 protein isoform produced from the proximally polyadenylated DOG1 mRNA is a key player in the establis

77 precursor stem-loop, which produces a short polyadenylated downstream mRNA, and that this trans-spli

78 ut the mechanisms by which these genomes are polyadenylated during viral replication remain obscure.

79 structure and transcription of D4Z4-encoded polyadenylated DUX4 mRNA in muscle.

80 ation reactions has no effect on turnover of polyadenylated edited RNA.

81 As contain no introns, and the mRNAs are not polyadenylated, ending instead in a conserved stem-loop

82 only eukaryotic cellular mRNAs that are not polyadenylated, ending instead in a conserved stem-loop.

83 ng to determine the precise 5'-capped and 3'-polyadenylated ends of postreplicative RNAs.

84 er, yielding a comprehensive atlas of 62,000 polyadenylated ends.

85 Using rG4-seq on polyadenylated-enriched HeLa RNA, we generated a global

86 We investigated how the long, polyadenylated Evf2 noncoding RNA regulates transcriptio

87 svirus produces a 1077 nucleotide noncoding, polyadenylated, exclusively nuclear RNA called PAN that

88 f 44 microRNAs (miRNAs), and the spliced and polyadenylated exons form nuclear non-protein-coding RNA

89 vation of the functional short alternatively polyadenylated form of the DOG1 mRNA.

90 f products was shifted to favor the distally polyadenylated form.

91 Polyadenylated forms of the 27S pre-rRNA and the 25S rRN

92 essing of the major pri-miR171a, spliced and polyadenylated forms of which accumulate in plants homoz

93 und that the drug causes the accumulation of polyadenylated fragments of the 27S rRNA precursor and t

94 ression of pre-mRNAs prematurely cleaved and polyadenylated from cryptic polyadenylation signals (PAS

95 was established for quantitative analysis of polyadenylated full-length (fl) and truncated (tr) HBV R

96 Interestingly, GppppA-capped and polyadenylated full-length mRNAs were also found to be s

97 omplex required for production of proximally polyadenylated functional DOG1 transcript.

98 substantial posttranscriptional increase in polyadenylated GAL1 3' ends.

99 ic polyA[+] RNA-seq, including novel and non-polyadenylated genes.

100 ranscript level information is needed beyond polyadenylated genes.

101 The polyadenylated H3.1 mRNA induced by arsenic was not susc

102 lular mRNA, translation of the uncapped, non-polyadenylated hepatitis C virus (HCV) genome occurs ind

103 results in accumulation of small amounts of polyadenylated histone mRNA and nascent read-through tra

104 There are also genes encoding polyadenylated histone mRNAs, which encode histone varia

105 f 7SK led to an enhanced ratio of cleaved to polyadenylated histone transcripts, an effect dependent

106 s2 depletion, concurrent with an increase in polyadenylated histone transcripts.

107 Processive, polyadenylated HIV-1 mRNAs were also present at a low le

108 ically, PARN cleaves the 3'-end of immature, polyadenylated hTR to form the mature, nonpolyadenylated

109 exon 2 leading to the production of a small polyadenylated HTTexon1 transcript, and the full-length

110 the question of how viral RNA is efficiently polyadenylated in the absence of splicing.

111 Most eukaryotic mRNAs are polyadenylated in the nucleus, and the poly(A)-tail is r

112 ranscripts encoding the capsid proteins were polyadenylated in the right-hand terminal palindrome.

113 t approximately 85% of viral transcripts are polyadenylated in vivo.

114 aordinary diversity of correctly spliced and polyadenylated intergenic transcripts.

115 ong the intervening DNA, synthesizing short, polyadenylated, intergenic RNAs to ultimately loop with

116 prise approximately 10% of B19 RNAs that are polyadenylated internally.

117 e Expression) sequencing to globally resolve polyadenylated isoform structures in replicating Epstein

118 lncRHOXF1 is a spliced and polyadenylated lncRNA about 1 kb in length that is found

119 ockd (lncRNA downstream of Cdkn1b), a 434-nt polyadenylated lncRNA originating 4 kb 3' to the Cdkn1b

120 Analysis of the mouse erythro-megakaryocytic polyadenylated lncRNA transcriptome indicates that ~75%

121 reduces the localization of both nascent and polyadenylated lncRNA transcripts to chromatin, and disr

122 We used RNA sequencing to identify 1109 polyadenylated lncRNAs expressed in erythroblasts, megak

123 et and another Alu element in a cytoplasmic, polyadenylated long non-coding RNA (lncRNA).

124 ion signal with sequences derived from a non-polyadenylated long non-coding RNA (MALAT1), which can f

125 Capped and polyadenylated long noncoding RNAs (lncRNAs) are shown t

126 Polyadenylated mature mRNAs are the focus of standard tr

127 sed on elevated affinity interaction between polyadenylated miRNA and bare gold electrode.

128 responses together with increased levels of polyadenylated mitochondrial transcripts.

129 nosomatid polycistronic transcripts produces polyadenylated monocistronic mRNAs modified to form the

130 xon 2 resulting in the production of a small polyadenylated mRNA (HTTexon1) that encodes the highly p

131 of target mRNAs produce diagnostic uncapped, polyadenylated mRNA fragments.

132 We demonstrate that hos1 mutants accumulate polyadenylated mRNA in the nucleus and that the circadia

133 adaptors that flag alternatively spliced and polyadenylated mRNA isoforms as cargo ready for the cyto

134 roteins (sFlt1s) produced from alternatively polyadenylated mRNA isoforms.

135 otein factors necessary for 3' processing of polyadenylated mRNA precursors are well known.

136 he oligo(dT)-primed reverse transcription of polyadenylated mRNA templates used to generate EST cDNA

137 its exact complement (the antigenome), and a polyadenylated mRNA that acts as a template for the smal

138 principally to a genomic region producing a polyadenylated mRNA that encodes a protein.

139 nt splicing of exon 1 HTT results in a short polyadenylated mRNA that is translated into an exon 1 HT

140 ion factors, mRNA binding proteins, and most polyadenylated mRNA.

141 SG-PB docking, and impaired preservation of polyadenylated mRNA.

142 in parallel the native 5' ends of uncapped, polyadenylated mRNAs and 3' ends of capped mRNAs from th

143 Polyadenylated mRNAs and replication-dependent histone m

144 mplexes-one specifically crafted to generate polyadenylated mRNAs and the other to generate nonpolyad

145 requires shortened/no poly(A)-tail targets; polyadenylated mRNAs are partially activated upon PAIP2

146 During heat shock, most polyadenylated mRNAs are retained in the nucleus, wherea

147 Together, these results suggest that polyadenylated mRNAs can enter P-bodies, and an mRNP com

148 d of the genome followed by 5'-capped and 3'-polyadenylated mRNAs from internal genes by a stop-start

149 They are expressed as polyadenylated mRNAs in fibroblasts differentiated in vi

150 of this system, including the prevalence of polyadenylated mRNAs in the bacterium, are still poorly

151 Transcription termination for genes encoding polyadenylated mRNAs requires a functional poly(A) signa

152 Analysis of the cellular distribution of polyadenylated mRNAs revealed more pronounced nuclear mR

153 erminal portion of DUX4 and (iii) capped and polyadenylated mRNAs that contain the double-homeobox do

154 Polyadenylated mRNAs were captured by oligo-dT primers a

155 s the genomic RNA to produce five capped and polyadenylated mRNAs with the 5'-terminal structure 7mGp

156 Since PABP1 binds to all polyadenylated mRNAs, and is involved in translation ini

157 nuclear export and also 3'-end processing of polyadenylated mRNAs, but whether such regulation also e

158 PABPC1 antagonizes uridylation of polyadenylated mRNAs, contributing to the specificity fo

159 addition, RNase R stalls in the body of many polyadenylated mRNAs, especially at G-rich sequences tha

160 ssed in terminally differentiated tissues as polyadenylated mRNAs, likely serving as replacement hist

161 eta-lactamase family generate the 3' ends of polyadenylated mRNAs, nonpolyadenylated histone mRNAs, a

162 n-independent histones, which are encoded by polyadenylated mRNAs, persists outside of S phase.

163 er half of human genes produce alternatively polyadenylated mRNAs, suggesting that regulated polyaden

164 e show that sequencing of oligo(dT)-selected polyadenylated mRNAs, without considering the orientatio

165 amyxoviruses produce capped, methylated, and polyadenylated mRNAs.

166 , similar to the mechanism of translation of polyadenylated mRNAs.

167 3'-end processing and nuclear export of non-polyadenylated mRNAs.

168 ns two sets of histone genes that encode non-polyadenylated mRNAs.

169 etween 3' end formation of histone mRNAs and polyadenylated mRNAs.

170 all capped RNAs, and selection of capped and polyadenylated mRNAs.

171 istone genes that encode histone variants as polyadenylated mRNAs.

172 quently yielded an accumulation of shortened polyadenylated mtRNA species and impaired mitochondrial

173 These capped, polyadenylated ncRNAs are transcribed across the large i

174 The remainder associates with non-polyadenylated non-coding transcription.

175 s, 19.4, 43.7, and 36.9% were observed to be polyadenylated, nonpolyadenylated, and bimorphic, respec

176 t REF/Aly is recruited to the KSHV noncoding polyadenylated nuclear (PAN) RNA by ORF57.

177 osi's sarcoma-associated herpes virus (KSHV) polyadenylated nuclear (PAN) RNA facilitates lytic infec

178 Stability of the long noncoding-polyadenylated nuclear (PAN) RNA from Kaposi's sarcoma-a

179 ith a 9-nucleotide (nt) core element of KSHV polyadenylated nuclear (PAN) RNA, a viral long noncoding

180 es a highly abundant, nuclear noncoding RNA, polyadenylated nuclear (PAN) RNA, which contains an elem

181 pesvirus (KSHV) transcribes a long noncoding polyadenylated nuclear (PAN) RNA, which promotes the lat

182 tial for the nuclear accumulation of a viral polyadenylated nuclear (PAN) RNA.

183 Lytic KSHV expresses polyadenylated nuclear RNA (PAN RNA), a long noncoding R

184 t, long, noncoding transcript referred to as polyadenylated nuclear RNA (PAN RNA).

185 ma-associated herpesvirus (KSHV) expresses a polyadenylated nuclear RNA (PAN RNA).

186 , ORF59, K8alpha, K8.1, or a higher level of polyadenylated nuclear RNA after butyrate induction and

187 the Kaposi's sarcoma-associated herpesvirus polyadenylated nuclear RNA contains a 79-nt cis-acting e

188 monomeric red fluorescent protein 1 (mRFP1), polyadenylated nuclear RNA promoter (pPAN)-enhanced gree

189 the Kaposi's sarcoma-associated herpes virus polyadenylated nuclear RNA) are not efficiently processe

190 paired in activating direct targets, such as polyadenylated nuclear RNA, and indirect targets, such a

191 ranscriptome showed that several viral RNAs (polyadenylated nuclear RNA, open reading frame 58 [ORF58

192 which we named lncRNA-CMPK2, was a spliced, polyadenylated nuclear transcript that was induced by IF

193 bearing two C-G*C(H+) interrupts), and (3) a polyadenylated nuclear-nuclear retention element complex

194 130 kb upstream of miR-21, are spliced, and polyadenylated only a few hundred base pairs upstream of

195 Capped and polyadenylated ORF0 mRNAs are present in the cytoplasm,

196 Nuclear polyadenylated (poly(A)) RNA in ZC3H3-depleted cells is

197 ts and reconstituted exosomes using AU-rich, polyadenylated (poly[A]), generic, and structured RNA su

198 in which we identify 72 factors required for polyadenylated [poly-(A(+))] mRNA export from the nucleu

199 idopsis continues to suggest the presence of polyadenylated (polyA) transcripts originating from pres

200 eviously undescribed prematurely cleaved and polyadenylated pre-mRNAs, some of which contain novel OR

201 or is required for processing of histone and polyadenylated pre-mRNAs.

202 as mRNAs, pre-mRNAs, or those RNAs that are polyadenylated prior to their degradation in the nucleus

203 found that human NLRP3 can be alternatively polyadenylated, producing a short 3'-UTR isoform that ex

204 rt that the yeast RPB2 gene is alternatively polyadenylated, producing two mRNAs with different lengt

205 d >28,000,000 signatures from the 5' ends of polyadenylated products of miRNA-mediated mRNA decay, is

206 BMP2 mRNAs are alternatively polyadenylated, resulting in mRNAs with distinct 3'-untr

207 We now demonstrate that Slr1 binds to polyadenylated RNA and that its intracellular localizati

208 rent biochemistries, with one examining only polyadenylated RNA and the other total RNA.

209 ogy from Pacific Biosciences to sequence the polyadenylated RNA complement of a pooled set of 20 huma

210 he viral genome is a single 7,400-nucleotide polyadenylated RNA encoding 11 proteins in a single open

211 Picornaviruses have 3' polyadenylated RNA genomes, but the mechanisms by which

212 APII binding and increased nuclear RNA, with polyadenylated RNA levels only elevated after prolonged

213 entary DNA samples, reverse-transcribed from polyadenylated RNA obtained from human liver tissue.

214 A polyadenylated RNA of 3.0 kb (T3.0) is transcribed from

215 ination of nonpolyadenylated as well as some polyadenylated RNA polymerase II transcripts.

216 This transcription is observed in polyadenylated RNA samples and appears to be derived fro

217 Inhibitor-free, genome-wide analysis of polyadenylated RNA stability via 5-EU pulse-chase experi

218 ughput method for reliable identification of polyadenylated RNA termini, and we apply this method, ca

219 rine Upregulated Gene 1 (TUG1) is a spliced, polyadenylated RNA that does not encode any open reading

220 quantification of the full range of cellular polyadenylated RNA transcripts using a Helicos Genetic A

221 Because RBDmap relies on the isolation of polyadenylated RNA via oligo(dT), it will not provide RN

222 In addition, sar1 sar3 plants accumulate polyadenylated RNA within the nucleus, indicating that S

223 Following RNA extraction and isolation of polyadenylated RNA, a 5'-RNA adapter that includes an Mm

224 not require molecular tagging or capture of polyadenylated RNA, and apply it to recover cross-linked

225 el approach to prepare 3' end fragments from polyadenylated RNA, and mapped the position of the poly(

226 r more limitations, such as focusing only on polyadenylated RNA, sequencing of only the 3' end of the

227 trated that XTUT7 repressed translation of a polyadenylated RNA, to which it added a distinct number

228 Men epsilon is a 3.2-kb polyadenylated RNA, whereas Men beta is an approximately

229 onine serine repeat protein (Gts1p), nuclear polyadenylated RNA-binding protein 3, and minichromosome

230 We sequenced polyadenylated RNA-derived complementary DNAs from 92 ps

231 s that contain pre-mRNA splicing factors and polyadenylated RNA.

232 y can be harnessed to identify alternatively polyadenylated RNA.

233 O2 into enlarged nuclear speckles containing polyadenylated RNA.

234 S avoids molecular tagging or the capture of polyadenylated RNA.

235 nscripts (BARTs) are the most abundant viral polyadenylated RNA.

236 is required for the 3'-end processing of non-polyadenylated, RNAPII-dependent, uridylate-rich, small

237 ding proteins (RBPs) are based on capture of polyadenylated RNAs and cannot recover proteins that int

238 to identify the set of TEs able to generate polyadenylated RNAs and create a new transcript-based an

239 t hydroxymethylcytosine preferentially marks polyadenylated RNAs and is deposited by Tet in Drosophil

240 BP3 positively impacts the nuclear export of polyadenylated RNAs and the expression of large multi-ex

241 Previous studies have looked at which polyadenylated RNAs are enriched in neuronal projections

242 s an exciting alternative whereby individual polyadenylated RNAs are sequenced directly, without the

243 generation sequencing to analyze and compare polyadenylated RNAs from abortive MOCV infections of sev

244 NA processing intermediates and suggest that polyadenylated RNAs have low stability in plants.

245 Proteins bound to polyadenylated RNAs in primary cultures of undifferentia

246 whether such regulation also extends to non-polyadenylated RNAs is unknown.

247 associations of human nuclear and cytosolic polyadenylated RNAs longer than 200 nucleotides (nt) and

248 Non-coding non-polyadenylated RNAs were among the key Hox targets, with

249 however, on capturing proteins associated to polyadenylated RNAs which neglects RBPs bound to non-ade

250 number that gave rise to heterogeneous Trf4p-polyadenylated RNAs with lengths of approximately 250-50

251 toplasm after its nuclear export, to degrade polyadenylated RNAs, such as mRNAs, pre-mRNAs, or those

252 on of ORF59 RNA and RBM15's association with polyadenylated RNAs.

253 The levels of polyadenylated rRNAs are dramatically increased in strai

254 The existence of polyadenylated rRNAs may reflect a quality-control mecha

255 ation-dependent histone mRNAs, which are not polyadenylated, share factors involved in 3' end formati

256 roborated by the finding that the proximally polyadenylated short DOG1 mRNA is translated in vivo and

257 e formation of paraspeckles by enhancing the polyadenylated short isoform of Neat1.

258 observed transcript 3' end heterogeneity and polyadenylated small nucleolar RNAs.

259 and characterized methylguanosine-capped and polyadenylated small RNAs (CPA-sRNAs) by using different

260 s of the Arabidopsis thaliana transcriptome (polyadenylated, small, and degrading RNAs).

261 wild-type, pre-tRNA(i)(Met) accumulates as a polyadenylated species, whose abundance and length distr

262 how that genes are also flanked by sense, 3' polyadenylated sRNAs that are likely to be capped.

263 on-coding RNAs, one of which generates a non-polyadenylated stable intron appearing to be a conserved

264 chet helix that influences Mtr4 affinity for polyadenylated substrates.

265 TT gene results in the production of a small polyadenylated transcript (Httexon1) that encodes the hi

266 of these clones corresponded to a capped and polyadenylated transcript containing a large portion of

267 An abundant, spliced, internally polyadenylated transcript encoded the viral NP1 protein

268 o examine murine gammaherpesvirus 68 (MHV68) polyadenylated transcript expression in a time course of

269 ed by a 28-nucleotide transcript and long 3'-polyadenylated transcript initiated with non-canonical G

270 miR-378* and thus renders the alternatively polyadenylated transcript insusceptible to miR-378*-medi

271 PCR and mRNA-seq detect a single capped and polyadenylated transcript that encodes processed forms o

272 t 49% (human), 31% (mouse), and 28% (rat) of polyadenylated transcription units have alternative poly

273 to contribute only a small percentage of the polyadenylated transcriptome in some RNA-Seq experiments

274 sequencing to characterize the developmental polyadenylated transcriptome of C. elegans Taking advant

275 RNA sequencing (RNA-seq) to characterize the polyadenylated transcriptomes of human and mouse platele

276 most of these methods focus on the 3'-end of polyadenylated transcripts and provide only a partial vi

277 the ENE-controlled rapid-decay mechanism for polyadenylated transcripts comprises a nuclear pre-mRNA

278 Ratios of encapsidated readthrough and polyadenylated transcripts for vectors with wild-type an

279 RRP6 result in the accumulation of aberrant polyadenylated transcripts from small nucleolar RNA gene

280 Noncoding functions of such polyadenylated transcripts have been elucidated in only

281 hroughput sequencing targeting the 3' end of polyadenylated transcripts in archived tumors from 24 ad

282 served that intron retention is prevalent in polyadenylated transcripts in resting CD4(+) T cells and

283 to modulate transcription termination of non-polyadenylated transcripts including snRNAs and mRNAs en

284 Here, we show that intron-less polyadenylated transcripts such as PAN RNA and beta-glob

285 n species has identified genes encoding long polyadenylated transcripts that do not contain ORFs of l

286 ng element, the ENE, which allows intronless polyadenylated transcripts to accumulate to high nuclear

287 We curated polyadenylated transcripts with limited protein-coding c

288 me capture methods to identify RBPs bound to polyadenylated transcripts within the first 2 h of Droso

289 f cytoplasmic XRN substrates have focused on polyadenylated transcripts, although many substrates are

290 for high-throughput sequencing of 3' ends of polyadenylated transcripts, and used it to globally map

291 ers fundamentally from normal termination in polyadenylated transcripts, as it leads to transcript de

292 a method is described to concurrently remove polyadenylated transcripts, prokaryotic rRNA, and eukary

293 s greater than those for 98% of all cellular polyadenylated transcripts.

294 on of 17 distinct, likely non-protein-coding polyadenylated transcripts.

295 more abundant than the other introns within polyadenylated transcripts; we classified these as "deta

296 n non-translating mRNPs, and the presence of polyadenylated uncapped mRNA in mRNPs was confirmed by s

297 The 5' ends of polyadenylated, uncapped mRNAs from Arabidopsis were dir

298 HuR mRNA exists as three alternatively polyadenylated variants, a 1.5-kb testes-specific mRNA i

299 n and RNA cleavage sites associated with all polyadenylated viral RNAs and demonstrate that low level

300 ding P19-generated transcripts are primarily polyadenylated within the central intron and not efficie