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1 incorporation of bromine and iodine into the polyamide.
2 h trimesoyl chloride, one of the monomers of polyamide.
3 eight, size, and color with the exception of polyamide.
4 pleting a closed loop cycle for recycling of polyamides.
5 hway may also be involved in the response to polyamides.
6 culties synthesizing these tandem hairpin PI polyamides.
7 ys and compared to the corresponding hairpin polyamides.
8 g liver toxicity was only observed for three polyamides.
9 nker affects on the cellular permeability of polyamides.
10 d (alpha-amino-gamma-turn)-linked eight-ring polyamides.
11 inting data of DNA binding pyrrole-imidazole polyamides.
12 tractive C5 building block of polyesters and polyamides.
14 abeled radioactive pyrrole-imidazole (Py-Im) polyamide 1, targeted to the 5'-WGWWCW-3' DNA sequence,
18 s that cause animal toxicity, we synthesized polyamides 1-4 with variations at the alpha- and beta-po
23 ing with automated data analysis showed that polyamide (39%) and ethylene-propylene-diene rubber (23%
25 th positively charged polymeric beads, e.g., polyamide 6/6 (Nylon) and polyoxymethylene (Delrin), and
26 ease of the nanofiller and transformation of polyamide-6 (PA6), a thermoplastic polymer widely used i
27 sited via atomic layer deposition (ALD) onto polyamide-6 nanofibers enable the formation of conformal
28 Bio-based unsaturated nylon-6,6 (unsaturated polyamide-6,6) was finally obtained by polymerization of
29 y developed novel porous nano-hydroxyapatite/polyamide 66 (nHP66)-based nanoscaffold materials contai
30 rpin with a second turn unit yields a cyclic polyamide, a lesser-studied architecture mainly attribut
31 To directly identify the binding sites of polyamides across the genome, we designed, synthesized,
33 averaged amide link scission in the aromatic polyamide active layer of a reverse osmosis membrane upo
34 uptake into the bulk region of the aromatic polyamide active layer of a reverse osmosis membrane upo
35 he partition coefficient of solutes into the polyamide active layer of reverse osmosis (RO) membranes
36 nterfacial polymerization, thereby forming a polyamide active layer with more uniform sub-nanometre p
37 s, and measurements of charge density in the polyamide active layers of reverse osmosis (RO) and nano
41 Small animal PET imaging of radiolabeled polyamides administered to mice revealed distinct differ
42 serum concentration was similar for all four polyamides after injection, dose-limiting liver toxicity
43 on between maleimides and resin-linked diene-polyamides allows the latter to be used in the preparati
44 quence specificity and binding affinity, six polyamide analogues containing the core triheterocyclic
46 the carbon nanotubes are embedded within the polyamide and form ester bonds with trimesoyl chloride,
48 ation by fractionation on Amberlite(R) XAD16 polyamide and semi-preparative reverse-phase HPLC column
49 tructed from a DNA-binding pyrrole-imidazole polyamide and the peptide FYPWMK facilitates binding of
50 DNA dimerizer constructed from a DNA-binding polyamide and the peptide FYPWMKG facilitates the bindin
54 s will influence the further design of Py-Im polyamides and facilitate their study in animal models.
55 ts point to a new design principle to deploy polyamides and perhaps other synthetic molecules to effe
57 ensile deformation has been applied to these polyamides and significantly enhances tensile strength t
60 ing oligonucleotides, peptide nucleic acids, polyamides, and other approaches, recognition of mixed-s
61 e nucleic acids (PNAs), minor groove binding polyamides, and--more recently--engineered proteins such
76 ar equivalents of DNA with a neutral acyclic polyamide backbone that has nucleobases attached via ter
77 minimum first step toward the translation of polyamide-based gene regulation from cell culture to sma
79 enome-wide view from live cells reveals that polyamide-based synthetic genome readers bind cognate si
80 ofiles, including hydrogen, of NaOCl-treated polyamide-based thin-film composite (TFC) membranes.
81 served results in which polyester fibers and polyamide beads triggered the most pronounced impacts on
82 x different microplastics (polyester fibers, polyamide beads, and four fragment types: polyethylene,
86 the impact of different chromatin states on polyamide binding in live cells remains an unresolved qu
91 crystal structure of an 8-ring cyclic Py/Im polyamide bound to the central 6 bp of the sequence d(5'
92 ta-amino turn-linked eight-ring cyclic Py-Im polyamide bound to the central six base pairs of the seq
94 oligonucleotides, peptide nucleic acids, and polyamides, but substantial efforts are currently devote
96 g elastomers from biomass-derived long-chain polyamides by thiol-ene addition copolymerization with d
98 constructed by attaching the peptide to the polyamide C-terminus expand the range of protein-DNA dim
99 thesis and characterization of a macrocyclic polyamide cage that incorporates redox-active 1,4-dithii
104 ute to the creation and application of these polyamide-carbon nanotube thin films is also reported.
106 o group on imidazole- and pyrrole-containing polyamides causes stacked polyamides to bind in the mino
108 the latter exhibiting 50% higher adhesion to polyamide coated crystals (mimicking an RO membrane surf
109 resent study, we synthesized tandem tetramer polyamides composed of four hairpin moieties, targeting
111 ze telomeres specifically, tandem hairpin PI polyamides conjugated with a fluorescent dye have been s
115 bation pattern caused by a sequence specific polyamide correlates with its in vitro binding preferenc
122 genome, we designed, synthesized, and tested polyamide derivatives that enabled covalent crosslinking
123 previously that a pyrrole-imidazole (Py-Im) polyamide designed to bind the consensus androgen respon
124 reached a maximum of approximately 25%, (iv) polyamide disintegration occurs when high free chlorine
125 the biological activity of pyrrole-imidazole polyamide DNA-binding molecules, we characterized the ag
126 igh-throughput analysis of pyrrole-imidazole polyamide DNA-binding specificity in a 10(12)-member DNA
128 ed covalent crosslinking and localization of polyamide-DNA interaction sites in live human cells.
133 reatment with this pyrrole-imidazole (Py-Im) polyamide exhibits sequence selectivity in its repressio
135 f a modified UiO-66-NH(2) MOF with a growing polyamide fiber (PA-66) during an interfacial polymeriza
136 ined velocities ranged between 0.39 cm/s for polyamide fibers (settling) and 31.4 cm/s for expanded p
137 g diffusivities of several alcohols within a polyamide film of commercial RO membrane using attenuate
140 amides more easily, we have developed new PI polyamide fragments and have used them as units in Fmoc
143 This study reveals that the combination of polyamide groups, open metal sites, appropriate pore geo
144 A facile modular approach toward cyclic polyamides has been developed via microwave-assisted sol
145 d, but the study of telomeres using these PI polyamides has not been reported because of difficulties
146 odeoxynucleotide decoys or pyrrole-imidazole polyamides) has demonstrated antitumor responses with mi
150 , e.g., polytetrafluoroethylene (Teflon) and polyamide-imide (Torlon), discharge when the like-charge
155 ynthetic alkylating agent (pyrrole-imidazole polyamide indole-seco-CBI conjugate; KR12) that selectiv
159 In enzalutamide-resistant LREX' cells, Py-Im polyamide interfered with both AR- and GR-driven gene ex
160 ve binding hairpin pyrrole-imidazole (Py-Im) polyamide interferes with RNA polymerase II (RNAP2) acti
163 minor groove recognition of a P.Z pair by a polyamide is the reduced level of allosteric distortion
166 ased monomers and polymers, and particularly polyamides, it should be noticed that very few natural a
167 membranes consist of a functional selective polyamide layer formed by highly reproducible interfacia
168 oscale nonuniformities inherently present in polyamide layer may reduce selectivity, e.g., for boron
170 the mechanism of phenol transport across the polyamide layer of RO membranes is studied using model p
171 Smoked meat sausages were packed into o-polyamide/low density polyethylene laminated film and co
174 a was centrifuged and passed over a 0.45-mum polyamide membrane filter, after which the extract was s
176 m that mimics the surface chemistry of an RO polyamide membrane was synthesized stepwise on gold-coat
177 As reverse osmosis (RO) and nanofiltration polyamide membranes become increasingly used for water p
178 ive to the long-existing thin-film composite polyamide membranes for water separation applications.
179 lute-solute separation can be achieved using polyamide membranes formed via surfactant-assembly regul
180 ar dynamic simulations, however, reveal that polyamide membranes have a distinctly different structur
182 d by reverse osmosis (RO) and nanofiltration polyamide membranes that are widely used for water purif
183 ine and chlorine-treated thin-film composite polyamide membranes with either MgCl2 or CaCl2 draw solu
184 anes compared to control thin-film composite polyamide membranes, in both reverse and forward osmosis
190 nderstand this effect, the reactivity of the polyamide monomer (benzanilide (BA)) with free chlorine
191 ndings provide a predictive model of how the polyamide monomer degrades during chlorine exposure and
192 igh-yielding routes to commercially valuable polyamide monomers using a single catalyst, telescopic w
194 s necessary for efficacy studies in animals, polyamides must be readily synthesized in solution.
195 rfacial polymerization to form free-standing polyamide nanofilms less than 10 nanometers in thickness
196 works (CAFs) by devitrification of amorphous polyamide network polymers using high-temperature and hi
198 utoxide) reacts with surface amide groups of polyamide nylon 6/6 to give (eta(2)-amidate)zirconium co
201 roperties of three pyrrole-imidazole (Py-Im) polyamides of similar size and Py-Im content but differe
202 e expression analysis of the effects of this polyamide on a set of glucocorticoid-induced and -repres
203 y stage therapeutic investigations involving polyamides or histone deacetylase inhibitors are being p
205 mers (G1-NH2) was covalently attached to the polyamide (PA) active layer of a commercially available
207 ng of the structure-property relationship of polyamide (PA) active layers in thin-film-composite memb
209 curring dsDNA-ssDNA telomere interface using polyamide (PA) and pyridostatin (PDS) conjugates (PA-PDS
210 ed the interactions of an eight-ring hairpin polyamide (PA) and two beta derivatives as well as a six
211 standing the effects of chlorine exposure on polyamide (PA) based membranes is essential in membrane
215 53(Al), NH2-MIL-53(Al) and MIL-101(Cr)] in a polyamide (PA) thin film layer were synthesized via in s
216 walled carbon nanotubes (MWCNT) and aromatic polyamide (PA), was successfully prepared by interfacial
218 ere the most abundant compounds, followed by polyamides, plastic-based paints, polyvinyl chloride, po
219 conformation in the densely charged aromatic polyamide poly(2,2'-disulfonyl-4,4'-benzidine terephthal
221 llular biopolymers, such as polysaccharides, polyamides, polyesters, polyphosphates, extracellular DN
225 , they are key monomers for the synthesis of polyamides, polyureas, polyepoxydes, which are all of gr
226 , and degradability of long-chain polyester, polyamides, polyurethanes, polyureas, polyacetals, and p
227 otency in cell culture, a focused library of polyamides possessing various modifications at the C-ter
228 d down by the biotin-labeled tandem tetramer polyamide probe confirmed its effective binding to telom
229 synthetic method of fluorescent tandem dimer polyamide probes composed of two hairpin moieties with a
231 new method, we synthesized four fluorescent polyamide probes for the human telomeric repeat TTAGGG,
232 xed cells with lower background signals than polyamide probes reported previously, suggesting that th
233 and fluorescence spectra of the fluorescent polyamide probes, and telomere staining in mouse MC12 an
236 owed by an acidic treatment that removes the polyamide protecting groups with no harm to the cycloadd
238 ma-turn increase the DNA-binding affinity of polyamides relative to the ( R)-alpha-amino-gamma-turn.
240 osaccharide purification uses a normal-phase polyamide resin (DPA-6S) in custom-made pipette tips.
243 assess the ionization behavior of nanoporous polyamide selective layers in state-of-the-art nanofiltr
244 ped TFC PRO membranes consist of a selective polyamide skin formed on the lumen side of well-construc
245 general purpose and specialty polyesters and polyamides; some of them are currently derived from oil,
247 e instruments included forceps, metallic and polyamide subretinal needles, and soft silicone-tipped i
249 e applied our methodology for solution-phase polyamide synthesis to cyclic polyamides with an improve
252 nce-specific agents, and it is the first non-polyamide, synthetic compound to specifically recognize
253 stigation of a DNA-binding pyrrole-imidazole polyamide targeted to bind the DNA sequence 5'-WGGWWW-3'
254 oximately 20-fold increase in the potency of polyamides targeted to the androgen response element (AR
257 turn potentiates the biological effects of a polyamide targeting the sequence 5'-WGWWCW-3' (W =A/T) b
258 a small library of hairpin pyrrole-imidazole polyamides targeting the sequence 5'-CGCG-3' and assesse
259 turn modifications enhance the uptake of all polyamides tested, while having a variable effect on the
260 ion, we designed a DNA minor groove-targeted polyamide that inhibits NES with low micromolar efficacy
263 king on the development of pyrrole-imidazole polyamides that bind to the minor groove of DNA in a seq
264 ctivity in N-methylpyrrole/N-methylimidazole polyamides that helps explain how these molecules locate
265 ing the intracellular concentration of Py-Im polyamides that will prove valuable for future applicati
266 s and specificities of the tandem hairpin PI polyamides, the UV-vis absorption and fluorescence spect
267 eriments with cellulose triacetate (CTA) and polyamide thin-film composite (TFC) FO membranes demonst
270 be reduced to a dipeptide WM attached to the polyamide through an epsilon-aminohexanoic acid linker w
273 pyrrole-containing polyamides causes stacked polyamides to bind in the minor groove of DNA in the sta
274 e N-terminus is important for the binding of polyamides to DNA in a stacked and staggered motif.
275 g of two bioactive and structurally distinct polyamides to genomes directly within live H1 human embr
280 probes have been proposed as alternatives to polyamides, triplex-forming oligonucleotides, and peptid
281 the biodistribution of a 5-ring beta-linked polyamide versus an 8-ring hairpin, which exhibited bett
285 The solubility of both hairpin and cyclic polyamides was increased upon addition of carbohydrate s
287 lutes and the membrane phase (fully aromatic polyamide) was computed from molecular dynamics (MD) sim
289 he presence of site-specifically bound Py-Im polyamides, we find that the pol II elongation complex b
292 Cyclooctyne-derivatized pyrrole-imidazole polyamides were immobilized on azide-modified glass subs
293 NA binding affinities of a library of cyclic polyamides were measured by DNA thermal denaturation ass
296 analysis by RNA-seq compares the DNA-binding polyamide with the well-characterized NF-kappaB inhibito
297 solution-phase polyamide synthesis to cyclic polyamides with an improved high-yield cyclization step.
298 of a new class of pyrrole-imidazole hairpin polyamides with beta-amino-gamma-turn units for recognit
299 These insights allow the redesign of hairpin polyamides with different turn units capable of distingu
300 ere, we report a class of easily processable polyamides with stereocontrolled mechanical properties a