ライフサイエンスコーパス: polyclonal

1 lculate the probability that a metastasis is polyclonal.

2 The IgE response to CHX seems polyclonal.

3 he binding reactivity of plasmablast-derived polyclonal Abs are reduced and do not increase in subseq

4 Polyclonal Abs isolated from HIV-infected subjects also

5 he binding reactivity of plasmablast-derived polyclonal Abs to the hemagglutinin of influenza A virus

6 In contrast, polyclonal activation of endogenous memory-like I-A(12%)

7 but also mismatches in HLA-DRB3 may induce a polyclonal allo-immune response associated with conversi

8 iferation, and cytokine production following polyclonal and antigen-specific stimulation.

9 Tumors are often polyclonal and are therefore heterogenous in their genom

10 s evolves to escape human immunity, which is polyclonal and can target many distinct epitopes.

11 hesized to be immune-dependent and typically polyclonal and high-grade disease to be immune-independe

12 ESR1 mutations are often polyclonal and longitudinal analysis shows distinct clon

13 Though polyclonal and monoclonal antibodies (Ab) can provide co

14 Reliable, specific polyclonal and monoclonal antibodies are important tools

15 ts of different lengths and tested them with polyclonal and monoclonal antibodies by inhibition enzym

16 ells were analyzed with flow cytometry after polyclonal and pathogen-specific stimulation (with varic

17 GFP(+)Tfh cells were found to be polyclonal and related to GFP(-)Tfh cells of Peyer's Pat

18 Using a series of polyclonal and transgenic self-reactive models harboring

19 e evolved antigenic sites effectively evades polyclonal anti-AAV1 neutralizing sera from immunized mi

20 e but not female mice born to dams harboring polyclonal anti-Caspr2 antibodies showed abnormal cortic

21 These data demonstrate that endogenous polyclonal anti-cytokine antibody responses can enhance

22 Polyclonal anti-D (Rh immune globulin [RhIg]) therapy ha

23 Polyclonal anti-D is a first-line therapy for immune thr

24 sive immunization of DENV-infected mice with polyclonal anti-DJ NS1 Abs reduced viral Ag expression a

25 functionalization of the sensor surface with polyclonal anti-Escherichia coli antibody allow to obtai

26 ELISA using polyclonal anti-HCP antibodies as reagents for capture,

27 f a high-throughput method that deconvolutes polyclonal anti-HCV NAbs in plasma, delineating the epit

28 (kappa-casein, timothy grass pollen extract, polyclonal anti-human IgE) were printed onto three diffe

29 immobilization of a coating antibody (Ab), a polyclonal anti-IgG, onto a treated PDMS surface.

30 1beta during an immune response could elicit polyclonal anti-IL-1beta antibody responses that modulat

31 The resulting polyclonal anti-IL-1beta antibody responses were assesse

32 Polyclonal anti-immunoglobulin G (anti-IgG) secondary an

33 Polyclonal anti-KEL immunoprophylaxis (KELIg) was admini

34 ond electrode is surface-functionalized with polyclonal anti-M1 antibodies, which then serve to ident

35 quently incubated with a fluorophore-labeled polyclonal anti-peroxidase antibody (anti-HRP-Alexa Fluo

36 rticles of ~22 nm diameter that reacted with polyclonal anti-Pfs47 antibodies, indicating that the an

37 A rabbit polyclonal anti-sPLA2-X antibody identified sPLA2-X by W

38 c deletion of IRAP fail to develop efficient polyclonal anti-tumour responses.

39 12), monoclonal antibodies (aIRR = 1.83), or polyclonal antibodies (aIRR = 2.03); in recipients who w

40 Human polyclonal antibodies (PAbs) are ideal, but this is depe

41 ls after the addition of either RSV-specific polyclonal antibodies (PAbs) or RSV glycoprotein-specifi

42 Biotinylated polyclonal antibodies against Escherichia coli were immo

43 es important for amyloidogenicity and raised polyclonal antibodies against the most amyloidogenic pep

44 Polyclonal antibodies against TNF-alpha suppressed TLR2/

45 ty one commercially available monoclonal and polyclonal antibodies against ZIKV and DENV envelope pro

46 Rabbit polyclonal antibodies and commercially available mouse m

47 s method utilizes oligonucleotide-conjugated polyclonal antibodies and quantifies antibody-antigen bi

48 In conclusion, these data show that polyclonal antibodies are superior to monoclonal antibod

49 To address the unmet needs for human polyclonal antibodies both as therapeutics and diagnosti

50 RNA immunoprecipitation assays) using m(6)A polyclonal antibodies coupled with mRNA isolation, quant

51 In parallel, after initial studies with polyclonal antibodies demonstrated the technical feasibi

52 orthogonal alkyne handle into monoclonal or polyclonal antibodies from different species in an Fc-sp

53 uthentic virus from infected individuals and polyclonal antibodies from vaccinees.

54 the protective efficacy of vaccine-elicited polyclonal antibodies has not previously been demonstrat

55 amplified via liposomes; (ii) the use of two polyclonal antibodies in the sandwich assay format incre

56 lopment of a Tc goat system expressing human polyclonal antibodies in their sera.

57 zed electrodes that are surface treated with polyclonal antibodies of glyphosate and a custom electro

58 nally, we demonstrate that SARS-CoV S murine polyclonal antibodies potently inhibited SARS-CoV-2 S me

59 o diagnostic test that utilizes a mixture of polyclonal antibodies raised against recombinant nucleop

60 standard membrane-feeding assays, anti-FREP1 polyclonal antibodies significantly blocked transmission

61 ination in the amount and the avidity of the polyclonal antibodies specific for the HA1 subunit of th

62 Treatment with monoclonal or polyclonal antibodies to PNAG (anti-PNAG) or vaccination

63 cochleae of different ages using custom-made polyclonal antibodies to TMC1 for light and transmission

64 the R5, G12 and Skerritt monoclonal and two polyclonal antibodies to well-defined gluten protein typ

65 imab use (pOR =3.03 (1.82, 5.04); I =0%) and polyclonal antibodies use for rejection (pOR = 3.92 [1.8

66 Polyclonal antibodies were generated against OTC molecul

67 ned monoclonal (outer surface protein A) and polyclonal antibodies were performed on all tissue secti

68 of EBOV-Zaire/Makona produced anti-Ebola IgG polyclonal antibodies with high neutralization activity.

69 fractionated human blood product containing polyclonal antibodies, act as immunomodulator peripheral

70 We used polyclonal antibodies, the TRAAK inhibitor RU2 and node

71 e aphid into plant tissues, we produced Me10 polyclonal antibodies.

72 dioimmunohistochemistry analysis using P2X7R polyclonal antibodies.

73 g synthesised and used for the production of polyclonal antibodies.

74 pentanoic acid-BSA (SA2-BSA) antigens toward polyclonal antibody (Ab-155).

75 obilized on the uWEs surface toward specific polyclonal antibody (Ab-TC), using a mixture of a fixed

76 EqCXCL16 or by pretreatment with guinea pig polyclonal antibody against EqCXCL16 protein (Gp anti-Eq

77 A rabbit polyclonal antibody against one of the same epitopes com

78 e assay was used to detect CpEF1alpha with a polyclonal antibody and host cell F-actin with rhodamine

79 using sandwich assay by utilising the rabbit polyclonal antibody as the capture antibody and conjugat

80 ed for sex, age, transplant year, and use of polyclonal antibody induction.

81 icacious against ZIKV, suggesting this human polyclonal antibody is a viable candidate for further de

82 and many antibodies in an antihenipavirus-F polyclonal antibody mixture (pAb835) also target this re

83 derived from the antigen-binding domains of polyclonal antibody mixtures.

84 ed using an immobilized goat anti-rabbit IgG polyclonal antibody on the SPR sensor chip.

85 ylactic or therapeutic administration of the polyclonal antibody preparations (TcPAbs) can protect mi

86 An anti-outer membrane protein A (OmpA) polyclonal antibody previously produced (in our laborato

87 has been confounded by the complexity of the polyclonal antibody response in humans.

88 ated protection correlated with induction of polyclonal antibody response that neutralized not only a

89 nstrate the induction of functionally active polyclonal antibody responses as measured in the standar

90 lineating the epitope specificities found in polyclonal antibody responses to HIV-1 infection.

91 immunogenicity studies revealed that similar polyclonal antibody responses were generated against ant

92 V-1 infection is associated with complex and polyclonal antibody responses, typically composed of mul

93 ion remains limited due to the complexity of polyclonal antibody responses.

94 ouse immunogenicity studies revealed similar polyclonal antibody responses.

95 o assess the quality of immunization-induced polyclonal antibody responses.

96 sing an NFAT reporter assay, we identified a polyclonal antibody that activates EMR2 G protein signal

97 A polyclonal antibody that targets the beta-subunit of the

98 An ovine polyclonal antibody therapy has been developed against E

99 e colostral anti-tumor necrosis factor (TNF) polyclonal antibody used in early clinical studies for t

100 sor chip was used to immobilise alpha-casein-polyclonal antibody using EDC/NHS coupling procedure.

101 For this, rabbit polyclonal antibody with specificity to C. jejuni was fi

102 a positive correlation with the anti-cod PAV polyclonal antibody, but no correlation with the anti-ca

103 ression was further confirmed using anti-B38 polyclonal antibody.

104 ntracellular ZIKV NS3, using a ZIKV-specific polyclonal antibody.

105 ulated that a bolus of enhanced IL-21-primed polyclonal antigen-specific CTL combined with CTLA4 bloc

106 e production in response to stimulation with polyclonal antigens or TAA.

107 Polyclonal antihuman thymocyte rabbit IgGs (antithymocyt

108 tirejection therapy with corticosteroids and polyclonal antilymphocyte globulin.

109 purified preparations of the resultant human polyclonal antisera against low- and high-dose VEEV chal

110 milarly, other epitopes identified using the polyclonal antisera overlap binding sites for previously

111 after affinity selection on rabbit anti-NoV polyclonal antisera revealed five families of overlappin

112 simultaneously from complex samples such as polyclonal antisera.

113 iruses with RBS deletions are able to escape polyclonal antiserum binding and are able to infect and

114 -pathogenicity H7N9 virus in the presence of polyclonal antiserum derived from ferrets infected with

115 o and in vivo Opsonization of Y. pestis with polyclonal antiserum modestly increased phagocytosis/kil

116 Initial evaluation of polyclonal antiserum resulting from immunization with a

117 To improve this strategy using a polyclonal approach, we developed a vaccine targeting VE

118 Early polyclonal ASC expansion, GC formation, and virus-specif

119 ng blood samples (r = 0.53 and P = 0.008 for polyclonal assay; r = 0.54 and P = 0.004 for monoclonal

120 e sought to investigate the possibility of a polyclonal autoimmune event in the airways of asthmatic

121 We report a "polyclonal" autoimmune event occurring in the airways of

122 pulation of Tregs that cannot fully suppress polyclonal autoreactive T cells.

123 In infected mice and NHP, polyclonal B cell activation and autoantigens secretion

124 otein A (SpA), a surface protein that drives polyclonal B cell expansion and induces cell death in th

125 in three study participants with persistent polyclonal B cell lymphocytosis (PPBL).

126 ee of self-reactivity in both monoclonal and polyclonal B cell repertoires.

127 Polyclonal Bim(-/-) and Bim(-/-)Nur77(-/-) mice exhibite

128 ileukemia activity of adoptively transferred polyclonal cancer antigen-reactive T cells deficient in

129 Thus, we conclude that in a polyclonal CD4 T cell repertoire, features of TcR-peptid

130 A dominant polyclonal CD4 T cell response against patient's mismatc

131 owever, in vivo effects of A2aR signaling on polyclonal CD4 T cells during a primary response to fore

132 during ART by triggering sequential waves of polyclonal CD4(+) T cell activation while simultaneously

133 ntial allogeneic immune synapse formation in polyclonal CD4(+) T cells using high-throughput imaging

134 Thus, the immunotolerance of polyclonal CD4(+) T cells was maintained by distinct mec

135 spectrum of helminth-induced effects on the polyclonal CD8 T response, indicating the lack of requir

136 o a stable marker of priming affinity within polyclonal CD8(+) T cell populations.

137 its role in shaping the naturally occurring polyclonal CD8(+) T cell repertoire has not been defined

138 on, because its development required non-TS1 polyclonal CD8(+) T cells.

139 enhanced IFN-gamma production compared with polyclonal cells, protected immune-deficient mice agains

140 erance determine the size and composition of polyclonal cohorts of autoreactive T cells with shared s

141 that patient-derived xenografts were highly polyclonal, consisting of tens to hundreds of LPC clones

142 ld increase in donor T(reg) engraftment, yet polyclonal donor T(regs) failed to reverse diabetes.

143 currently used in clinical trials are either polyclonal, donor- or antigen-specific.

144 that, when TnBVank1 was stably expressed in polyclonal Drosophila S2 cells, apoptosis is induced.

145 iple clones of low abundance, confirming the polyclonal expansion of HTLV-1-infected cells in vivo HT

146 t stimulates an immune response, followed by polyclonal expansion of Th17/Th1 cell subsets with relea

147 In MCD, infected B cells, although polyclonal, express a monotypic immunoglobulin Mlambda p

148 fluoresceinated IgG constant H chain-binding polyclonal F(ab')2 (IgHPolyFab) is used as the fluoresce

149 ified as a result of the binding of multiple polyclonal Fabs to the C region of primary IgH.

150 aive B cells and subsequently drive a robust polyclonal germinal center response in order to amplify

151 Transient p53 inhibition restored polyclonal graft composition.

152 strain, resistant to neutralization by both polyclonal-HCV-infected plasma and multiple broadly neut

153 Cases with polyclonal hematopoiesis might represent hereditary diso

154 therapy against diphtheria has been based on polyclonal horse sera directed against DT (diphtheria an

155 mpetitively released upon exposure to either polyclonal human (p < 0.0001) or rat (p = 0.0017) immuno

156 gen-specific highly neutralizing therapeutic polyclonal human antibody (TcPAb) preparations in 6 mont

157 in the alpha1KI mouse model, which produces polyclonal human IgA1 prone to mesangial deposition.

158 rface protein affect viral neutralization by polyclonal human sera.

159 f HIV-infected individuals develop a cognate polyclonal humoral response comprising very potent and e

160 Reactive T cells were polyclonal (ie, they expressed CD4 and CD8), T-helper ty

161 We compared the binding patterns of both polyclonal IgA subclasses to commensals and glycan array

162 Polyclonal IgE idiotypes in patients with CRSwNP are fun

163 s often characterized by local production of polyclonal IgE idiotypes.

164 protective in vitro and in vivo efficacy of polyclonal IgG against the M. tuberculosis capsular poly

165 ated a proven technology platform to produce polyclonal IgG fragments, F(ab')2, against EBOV.

166 Preincubation of polyclonal IgG with CD64-IgE Fc established allergen-spe

167 Treatment with rabbit polyclonal IgGs in the absence of additional immunosuppr

168 om wild-type mice, as well as by engineering polyclonal Ighgamma1/gamma1 and Ighepsilon/epsilon mice,

169 that separate the effects of CSR and SHM on polyclonal immune responses.

170 resistance to in vitro neutralization by MV polyclonal immune sera without altering its thermostabil

171 One of these designs showed improvement in polyclonal immune serum binding to HCV pseudoparticles a

172 lls to expand and mature in the context of a polyclonal immune system and produced serologic response

173 le tumors in Pfp-/- Rag2-/- mice were highly polyclonal, immunoedited tumors in WT and Pd-1-/- mice d

174 Here, we characterized polyclonal immunoglobulin Gs (IgGs) and Fabs from COVID-

175 genous human monoclonal immunoglobulins with polyclonal immunoglobulins background.

176 ce of mixed L2/L4 profiles was suggestive of polyclonal infection in the region, although this would

177 e haplotypes comprising as little as 2% of a polyclonal infection.

178 ution to discriminate related from unrelated polyclonal infections than biallelic SNP barcodes.

179 Genomic analyses revealed that all clones in polyclonal infections were cleared at the same rate, ind

180 heterozygosity [HE] = 0.75) and complex: 67% polyclonal infections, mean multiplicity of infection (M

181 ependent effector functions are regulated by polyclonal influenza virus-binding antibody mixtures in

182 profiles, and found that both monoclonal and polyclonal iNKT cells differentiated into functional sub

183 munogenic and cross-reactive with MOG at the polyclonal level, it fails to expand a threshold level o

184 itis, inflammatory arthropathy, intermittent polyclonal lymphoproliferation, and significant chronic

185 Overall, our study sheds light on the polyclonal MBC response to DENV and ZIKV in naive and DE

186 In this study, we analyzed polyclonal MBCs at the single-cell level from peripheral

187 Thus, the polyclonal memory B cell compartment is composed of B ce

188 The development of polyclonal memory B cells (MBCs) to the 4 DENV serotypes

189 promote metastatic progression and generate polyclonal metastases composed of driver and neutral sub

190 gut, undergo a collective migration and seed polyclonal metastases.

191 tween very similar antibodies present within polyclonal mixtures.

192 Rapid hematopoietic recovery with polyclonal multilineage engraftment of vector-marked cel

193 CD34(+) cell products are capable of stable, polyclonal multilineage reconstitution with follow-up of

194 By treating glioma cell lines with the polyclonal N-20 antibody against surface-localized GRP78

195 In this study, we found that polyclonal naive murine B cell populations specific for

196 ouse model (EF4.1) expressing a limited, yet polyclonal naive T-cell repertoire was used.

197 The polyclonal nature infections in high transmission settin

198 Single-cell studies highlighted the polyclonal nature of intratumoral resistance mechanisms

199 Importantly, the polyclonal nature of resistance remains underexplored.

200 The polyclonal nature of strains revealed by whole-genome se

201 The apparent polyclonal nature of the isolates suggests de novo emerg

202 l now, but the reliability, pan-specificity, polyclonal nature, and stability of the available pan-sp

203 PBMC or polyclonal NK cells isolated from normal donors served a

204 t lysis of articular chondrocytes by PBMC or polyclonal NK cells was potentiated by stimulation with

205 th PARP1 inhibitors, followed by transfer of polyclonal NK cells, suppresses leukaemogenesis in patie

206 ction inhibited CDC induced by AQP4 rAbs and polyclonal NMO patient sera.

207 In polyclonal NOD mice, a high frequency (~40%) of HIP2.5-s

208 ated and significantly more suppressive than polyclonal or DeltaCAR Tregs in the presence of HLA-A2,

209 60% of the cohort had induction therapy with polyclonal or monoclonal antibodies, 28% did not receive

210 urified recombinant or natural allergens and polyclonal or monoclonal antibodies.

211 and CD8+ T cell proliferation in response to polyclonal or SIV-specific stimulation.

212 , whereas moderate expansions are frequently polyclonal (p < 0.0001).

213 gainst BRCA deficiencies in cancer cells and polyclonal patient-derived xenograft models, including t

214 is was performed in seven infants and showed polyclonal patterns without clonal dominance in all seve

215 ron microscopy, we examined specificities of polyclonal plasma Fabs, revealing recognition of both S1

216 rmation rich genomic regions to characterize polyclonal Plasmodium falciparum infections.

217 s, granulocytes, B cells, and T cells from a polyclonal pool of hematopoietic stem and progenitor cel

218 ere was rapid engraftment and expansion of a polyclonal pool of transgene-positive functional T cells

219 expression of Nur77GFP and OX40 identifies a polyclonal population of high-affinity tumor-associated

220 Two c-MycER(TAM)-derived polyclonal populations, PA5 and PA7, were generated and

221 T cells increased following infection in the polyclonal populations, suggesting an increase in pathog

222 ned clone-specific chromosomal aneuploidy in polyclonal populations.

223 d to dissect the molecular mechanisms within polyclonal populations.

224 l and stromal compartments of monoclonal and polyclonal primary and metastatic lesions revealed that

225 , with a syndrome characterized by the rapid polyclonal proliferation and infiltration of CD4(+) CD25

226 ful model for studying the HTLV-1-associated polyclonal proliferation of CD4(+) T cells and viral int

227 +) T cells underwent an immediate TCR-driven polyclonal proliferation within the first 4 wk of life.

228 ae was expressed and purified and raising of polyclonal rabbit anti-OmpW was done.

229 Polyclonal reactivity of IgG antibodies was highest agai

230 ed with the ability to phenotype a patient's polyclonal repertoire in the same analysis further shows

231 showed a positive safety profile and highly polyclonal repertoire in vitro and at early time points

232 in-resident memory T cells that arise from a polyclonal repertoire of cells induced by infection with

233 tegy for studying clonal deletion within the polyclonal repertoire.

234 rs of broadly neutralizing antibodies within polyclonal repertoires, we developed an immunogen, RC1,

235 ial vaccination strategies in the context of polyclonal repertoires.

236 The anti-CA09 HA polyclonal response in this donor comprised 24 persisten

237 Deconvoluting the epitope specificities in a polyclonal response is a challenging task.

238 ubset of IGHV genes, progressing to a highly polyclonal response of B cells with broader IGHV gene us

239 ss-reactivity with MOG-specific T cells, the polyclonal response to NFM15-35 did not expand threshold

240 inity, MOG-specific T cells that defined the polyclonal response.

241 gent features on the background of a larger, polyclonal response.

242 BVANK1 and Alix proteins in the cytoplasm of polyclonal S2 cells.

243 by an antibody targeting DNA-RNA hybrids and polyclonal secondary antibody, all performed without was

244 tiates and drives systemic metastasis, where polyclonal seeding between sites is common.

245 lticolor lineage tracing to demonstrate that polyclonal seeding by cell clusters is a frequent mechan

246 Polyclonal seeding was common in untreated lymph node me

247 In the second patient, we observed polyclonal seeding, in which two independent clones seed

248 evident in reductionist systems, deletion of polyclonal self-specific CD8(+) T cells by cDC1 plays a

249 DS-PAGE and immunoassay analysis with rabbit polyclonal sera and human IgE indicated only minor diffe

250 Mapping the polyclonal sera by electron microscopy revealed that ant

251 as standardized reagents to monitor complex polyclonal sera for neutralization activity and to chara

252 The polyclonal sera of the three donors also reflect this pr

253 ltiple specificities of epitopes targeted in polyclonal sera, elicited in immunized animals as well a

254 uated the anti-HIV Ab effector activities in polyclonal serum samples from HIV-infected donors, VAX00

255 howed a more similar response profile across polyclonal serum samples.

256 er, the subpopulation of antibodies within a polyclonal serum that confer protection remained undefin

257 Polyclonal serum was verified for strong Zika virus-neut

258 eactivity profile was similar to that of the polyclonal serum, with the added benefit of being more s

259 d a rapid, sensitive, and robust method, the polyclonal serum-based proximity ligation assay (polyPLA

260 led rapid suppression of exon recognition in polyclonal settings to identify functional roles for ind

261 itoneal sites, and two patients demonstrated polyclonal spread and reseeding.

262 y flagellin-reactive CD4 cells compared with polyclonal stimulation or Candida albicans Ag exposure.

263 d activation by CD4(+) and CD8(+) T cells on polyclonal stimulation, and displayed lower major histoc

264 y reduced and hyporesponsive to cytokine and polyclonal stimulation.

265 well as in B cell culture supernatants after polyclonal stimulation.

266 ss interferon gamma and interleukin 17 after polyclonal stimulation.

267 ome (TSS), bacterial superantigens trigger a polyclonal T -cell response leading to a potentially cat

268 Conversely, the disease was driven by a polyclonal T cell population directed against self-antig

269 regulated the activation of Ag-specific and polyclonal T cells as well as clearance of dominant Ag i

270 but fails to induce demyelinating disease by polyclonal T cells despite having the same TCR contact r

271 CD8(+) T cells and in fibrosarcoma-reactive polyclonal T cells enhanced the persistence of PD-1 gene

272 We found that c-MPL(+) polyclonal T cells expand and proliferate in response to

273 itumor T cell responses, yet detecting these polyclonal T cells is challenging.

274 Polyclonal T cells paralleled these findings, with naive

275 to express synthetic receptors that redirect polyclonal T cells to surface antigens for subsequent tu

276 ility of ImmTAV-Env to activate and redirect polyclonal T cells toward cells containing integrated HB

277 n this study, we investigated the ability of polyclonal T(regs) to form functional memory in response

278 T-cell regulation, estimated as responses to polyclonal T-cell activation.

279 ods, APC-ms facilitates several-fold greater polyclonal T-cell expansion and improved antigen-specifi

280 While AD harbors a highly polyclonal T-cell receptor repertoire, and despite the l

281 of LF, we observed robust activation of the polyclonal T-cell repertoire, which included LASV-specif

282 sidue Glu(3) have a broad negative impact on polyclonal T-cell responses.

283 ncrease in IL-17A (P = .03) production after polyclonal T-cell stimulation, and an enhanced IL-10 res

284 lesional and nonlesional AD showed a highly polyclonal TCR pattern, without evidence of oligoclonal

285 A polyclonal TCR repertoire, an activated/memory phenotype

286 HC-multimer libraries used to probe diverse, polyclonal TCR repertoires in various settings.

287 ining lymph nodes compared to endogenous and polyclonal transferred Tregs.

288 In a polyclonal Treg cell replacement system, naive conventio

289 ed normal suppressive function in peripheral polyclonal Treg cells from patients with celiac disease,

290 y reduced suppressive function compared with polyclonal Treg cells.

291 We used CAR technology to redirect human polyclonal Tregs toward donor-MHC class I molecules, whi

292 d a model where the TCR repertoire of normal polyclonal Tregs was limited by serial transfers into IL

293 IL-2 with donor-specific Tregs, but not with polyclonal Tregs, a synergistic effect in prolonging ski

294 Emerging data indicate that, compared with polyclonal Tregs, disease-relevant antigen-specific Treg

295 protection from graft rejection compared to polyclonal Tregs.

296 lood mononuclear cells more effectively than polyclonal Tregs.

297 se associations are particularly enriched in polyclonal tumors, representing a constellation of featu

298 man primates and humans points to a role for polyclonal vaccine-induced antibody responses in protect

299 s (63 of 161), of whom 49.1% (27 of 55) were polyclonal, with rates of mutation detection unaffected

300 Four studied vaccinees show polyclonal, yet reproducible and convergent B cell respo