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1 LOH at 9p21-22 using eight different highly polymorphic marker.
2 17 through a pedigree, similar to a typical polymorphic marker.
3 Seq overcomes limitations inherent to length-polymorphic markers.
4 All individuals were genotyped for 23 highly polymorphic markers.
5 pped by FISH or by loss of heterozygosity of polymorphic markers.
6 these clusters could be detected with linked polymorphic markers.
7 ed using six 18p11 and one 18q12.3 PCR-based polymorphic markers.
8 ned the entire autosomal genome by using 367 polymorphic markers.
9 mative mtDNA (haplogroups H and L) and Y Alu polymorphic markers.
10 les showed the same haplotype for these five polymorphic markers.
11 y, we developed 11 new STSs, including seven polymorphic markers.
12 ed to identify and provisionally localize 25 polymorphic markers.
13 characterized by using a panel of 10 highly polymorphic markers.
14 in a large U.S. kindred, using 312 different polymorphic markers.
15 th trinucleotide- and tetranucleotide-repeat polymorphic markers.
16 ften necessary to genotype a large number of polymorphic markers.
17 e idealized context of a dense set of highly polymorphic markers.
18 rrounding the VHL locus using four different polymorphic markers.
19 ng genetic map information for large sets of polymorphic markers.
20 tched normal DNA using 22 highly informative polymorphic markers.
21 , for LOH at all 41 chromosomal arms with 50 polymorphic markers.
22 and 232,271 SNPs, with a subset validated as polymorphic markers.
23 samples was comparable or higher than length-polymorphic markers.
24 rozygosity (LOH) was evaluated with multiple polymorphic markers.
25 R analysis was used to type four independent polymorphic markers.
26 Genotyping was performed using polymorphic markers.
27 s standard genotyping method based on length-polymorphic markers.
28 a genome scan with 65 simple sequence length polymorphic markers.
29 n (order and distances) for any large set of polymorphic markers.
30 performed using >200 simple sequence-length polymorphic markers.
31 easure linkage disequilibrium between highly polymorphic markers.
32 sis was performed on 330 families, using 401 polymorphic markers.
33 ation of the defective gene by use of random polymorphic markers.
34 by low throughput and a lack of informative polymorphic markers.
35 nkage and linkage disequilibrium using known polymorphic markers.
36 clone onto which 71 markers were mapped: 23 polymorphic markers, 12 genes, 24 ESTs, and 12 random ge
37 B genes was constructed using 68 markers: 25 polymorphic markers, 15 known genes, 21 ESTs, and 7 rand
38 .CAST F2 female mice using a large number of polymorphic markers; (2) the generation of congenic subl
39 he B-NHL tumor panel, 24 additional 6q26-q27 polymorphic markers (21 mapping to the contig) further d
40 ns 200 PACs, 10 known genetic markers, 5 new polymorphic markers, 57 sequence tagged sites (STSs) gen
41 ple ascertainment of disease chromosomes and polymorphic markers, a genetic dominance model of diseas
42 Because palindromic insertions were used as polymorphic markers, a significant number of recombinant
44 milies affected by prostate cancer, using 17 polymorphic markers across a 98.5-cM segment of chromoso
46 the extent of these microdeletions by using polymorphic markers afforded further refinement of this
47 ll show substantial allelic variation in the polymorphic marker among the racial-ethnic groups of gre
52 n a framework of 40 known and 3 newly cloned polymorphic markers and 37 new sequence-tagged sites.
53 epresented by 872 unique STSs, including 642 polymorphic markers and 957 bacterial artificial chromos
54 lineal multiplex pedigrees), using 10 highly polymorphic markers and a range of parametric and nonpar
55 rnative genetic maps as they can include non-polymorphic markers and are also powerful enough to orde
57 uilibrium test to detect association between polymorphic markers and discrete or quantitative traits
58 osome 12 in 100 primary ALL samples using 22 polymorphic markers and identified two distinct smallest
59 cial chromosome contig that contains several polymorphic markers and is close to a polymorphic marker
60 200 STSs that include 25 dinucleotide repeat polymorphic markers and more than 80 expressed sequences
61 gene (LHCGR; 2p21), telomeric to the D2S123 polymorphic marker, and centromeric to the calmodulin-2
62 l between D19Umi1 and D19Mit9, developed new polymorphic markers, and mapped candidate genes by const
63 or the rapid and efficient identification of polymorphic markers, and through a World Wide Web site,
65 es, combinations of several phase-determined polymorphic markers, are extremely valuable for studies
66 members were recruited for the study, and 16 polymorphic markers around the AT3 gene were analyzed.
67 Additional analysis with other families and polymorphic markers as well as evaluation of potential c
68 The strong correlations demonstrated between polymorphic markers assessed by the four independent fin
72 ly facilitates the identification of YACs or polymorphic markers at specific locations in the genome.
75 The polymorphic index content (PIC) of 55 polymorphic markers averaged 0.407, ranging from 0.033 t
76 hic clusters between diploid species, 47 116 polymorphic markers between cultivated and interspecific
77 also report the identification of eight new polymorphic markers between D19S406 and D19S912, which a
78 We have isolated and analyzed four novel polymorphic markers between DXS7117 and DXS559 and, by h
79 lication that automates the discovery of new polymorphic markers between ecotypes of Arabidopsis thal
80 argeted chromosomal regions for isolation of polymorphic markers, building bacterial artificial chrom
82 alyzed 94 progeny for the segregation of 301 polymorphic markers, consisting of 228 restriction site
83 lution, we performed haplotype analysis of 8 polymorphic markers covering 340 kb spanning the VHL gen
84 nkage map of chromosome 21q using 187 highly polymorphic markers covering almost the entire long arm;
86 GAAn were selected for analysis at anonymous polymorphic markers D11S1364 and D11S1356, which flank t
87 m typing analysis was also performed using a polymorphic marker, D14S1050, closely linked to the MJD1
88 nkage analysis using DNA from the family and polymorphic marker D14S288 in chromosome 14q12 produced
91 ion fraction 0, between the BO phenotype and polymorphic marker D1S2757 in the genetic region of chro
97 rresponds to the genetic interval flanked by polymorphic markers D2S119 and D2S378 and covers a genet
100 he region of chromosome 2 encompassed by the polymorphic markers D2S378 (centromeric) and D2S391 (tel
103 ified by polymerase chain reaction using the polymorphic markers D3S2452, D3S1110, D3S192, and D3S656
104 14B4, 951G9, 981D6, and 847B3), and a nearby polymorphic marker (D4S1538) on chromosome 4 was identif
108 s tumours using a panel of 10 microsatellite polymorphic markers distributed along the length of the
109 e typing yielded identification of 127 novel polymorphic markers distributed throughout the class II
110 show that the crossover is between two novel polymorphic markers, DXS8349 and M6, both of which are p
111 that even a moderately spaced set of highly polymorphic markers (e.g., one every 0.8 cM) has high po
114 es and five unaffected individuals, using 40 polymorphic markers evenly distributed throughout the X
115 children and the other from the parents, 161 polymorphic markers evenly spaced across the autosomal h
118 locus by the lack of its cosegregation with polymorphic markers flanking the EDA locus in three of f
121 apped relative to other markers in 15q13 and polymorphic markers flanking tjp-1 were identified.
122 pped among hybrid F2s with single nucleotide polymorphic markers, followed by candidate gene sequenci
125 t microsatellites are a ubiquitous source of polymorphic markers for human adenoviruses and demonstra
126 show that AtPRIMER accurately found specific polymorphic markers for our linkage mapping project.
127 hysical map will facilitate the isolation of polymorphic markers for refinement of the disease gene r
128 egions harbouring putative TSG's between the polymorphic markers for the LPL gene-D8S298 (approximate
130 due to a founder effect, we identified five polymorphic markers (four diallelic markers and one CA r
132 nce tagged site (STS) content using the five polymorphic markers from above, four novel STSs identifi
134 Twenty-eight HCC cases were studied with polymorphic markers from different parts of the genome.
135 Segregation patterns of short tandem repeat polymorphic markers from four chromosomes revealed null
139 to map disease genes that, in a dense map of polymorphic markers, has considerably higher resolution
142 y map genes even in populations for which no polymorphic markers have been previously identified.
143 ar studies that use a large number of highly polymorphic markers have been undertaken to understand t
145 e identified a unique simple sequence repeat polymorphic marker (hLMX1.2CA1) in a P1 genomic clone co
147 alysis using 30 Simple Sequence Repeat (SSR) polymorphic markers identified significant marker-trait
148 g rate, and refractoriness), genotyped at 70 polymorphic markers in 10 male reproductive genes, and m
150 by multipoint genetic linkage analysis of 22 polymorphic markers in 40 F2 progeny of Fischer (F344/N)
151 whole-genome scan was carried out using 119 polymorphic markers in 633 (MRLxSJL) F2 female mice.
152 d LOH for DNA sequences on 7q with 10 highly polymorphic markers in 92 matched normal/tumor samples r
153 laboratory findings and were genotyped with polymorphic markers in a candidate region on human chrom
156 l statistical method for linkage analysis of polymorphic markers in a full-sib family of autotetraplo
160 PS gene, we present linkage analysis with 13 polymorphic markers in five families with a total of 69
162 These maps provide locations for genes and polymorphic markers in sequence and on genetic linkage,
163 lification and electrophoresis of individual polymorphic markers in the acute and recurrent blood sam
165 straight theta=.00) for the HGF phenotype to polymorphic markers in the genetic region of chromosome
168 nscription units and ordered with respect to polymorphic markers in the region, resulting in a compre
169 ermined by simultaneously genotyping several polymorphic markers in the same reaction with a multiple
170 milies confirmed both significant linkage to polymorphic markers in this region and incomplete penetr
176 everal polymorphic markers and is close to a polymorphic marker located at 95.8 cM on the Genethon li
178 s from an extensive MEN1 kindred using eight polymorphic markers located on chromosome 11q13, includi
180 the ODD locus was instigated and linkage to polymorphic markers located on chromosome 6q established
182 mating linkage disequilibrium (LD) between a polymorphic marker locus and any one of the loci affecti
184 e order of and physical distance between 180 polymorphic markers, many from the Genethon and CHLC gen
185 nalysis of 67 normal-tumor DNAs utilizing 20 polymorphic markers mapped to 12q22-q24, we identified t
186 normal-tumor DNAs from male GCTs assaying 24 polymorphic markers mapped to both the short and long ar
190 Amp-Seq markers were superior to length-polymorphic marker msp2 in detecting minority clones (se
191 cludes the largest set, to our knowledge, of polymorphic markers (N=14,759) for which genotype data a
192 e families with acheiropodia, by means of 15 polymorphic markers, narrowed the critical region to 1.3
193 describe an approach for identifying highly polymorphic markers near candidate genes that utilizes t
194 haplotype incorporating 3 single-nucleotide polymorphic markers near the translocation break point o
196 umours show loss of heterozygosity (LOH) for polymorphic markers on 11q13, the site of the MEN1 tumou
198 he development of ovarian cancer, we used 23 polymorphic markers on 6q to examine allelic loss in 25
201 putative tumor suppressor gene, we have used polymorphic markers on chromosome 3q to define the minim
204 nce of allelic imbalance at 5 microsatellite polymorphic markers on chromosomes 7q31-35, 8p12-21, 8p2
207 Coupled with the recent development of new polymorphic markers on the Y, making it the best-charact
210 cted relative pairs and dense sets of highly polymorphic markers or by emerging techniques such as ge
211 Ashkenazim, were genotyped with 10-14 highly polymorphic markers overlying each candidate region.
213 ome-wide haplotypes and a dense map with one polymorphic marker per approximately 2.3 kilobases.
214 primer combinations, with an average of 4.8 polymorphic markers per SSR across 34 Peronosclerospora,
215 rial clones, but the placement of 25 ("CA")n polymorphic markers permits the ordering of contigs by c
216 l and NSCLC tumor samples using 11 PCR-based polymorphic markers positioned approximately every 2-3 c
217 te of programs, collectively called POMPOUS (polymorphic marker prediction of ubiquitous simple seque
218 gh millions of reads to distill high-quality polymorphic markers requires special algorithms tailored
221 letion analysis of immortal segregants using polymorphic markers revealed the loss of a 2.9 Mbp inter
226 enia or schizoaffective disorder, 396 highly polymorphic markers spaced approximately 10 centimorgans
228 predisposition does not map to any of eight polymorphic markers spanning 1p36 by linkage analysis in
229 of these positive findings, eight additional polymorphic markers spanning a 63-cM region around AT1 l
230 t the results of a linkage analysis using 10 polymorphic markers spanning approximately 37 cM in the
232 ed for loss of heterozygosity (LOH) using 10 polymorphic markers spanning chromosome 6 including one
234 oss of heterozygosity (LOH) on 11q13 with 10 polymorphic markers spanning the area of the putative ME
235 rs with autoimmune thyroid disease for eight polymorphic markers spanning the cytotoxic T lymphocyte
236 -characterized BOR families with a set of 13 polymorphic markers spanning the D8S165-D8S275 interval
237 LOH analysis was performed using nine mapped polymorphic markers spanning the entire chromosomal arm.
238 diagnosed XLRP was scored with more than 34 polymorphic markers spanning the entire X-chromosome, in
242 e chromosome 6 telomere was constructed, and polymorphic markers spanning this region were defined.
247 ed in conjunction with genotypes from highly polymorphic markers, such as DNA microsatellites or comm
248 d penetrance has failed to show linkage with polymorphic markers, suggesting either locus heterogenei
250 ge thin polyacrylamide gels and reveals more polymorphic markers than agarose gel electrophoresis.
252 kage disequilibrium (MALD) requires a map of polymorphic markers that differentiate between the found
253 hort tandem repeat (STR) variants are highly polymorphic markers that facilitate powerful population
255 e selective AFLP primers and identified 1048 polymorphic markers that mapped to 468 unique loci on ni
256 from this family was genotyped with 6 highly polymorphic markers that span the DGI-II critical region
257 f newly identified transcribed sequences and polymorphic markers that will aid in linkage and linkage
258 ng, between a quantitative-trait locus and a polymorphic marker; this is achieved in the variance-com
261 ted males shared the same haplotype of eight polymorphic markers tightly linked to COL4A5, indicating
262 erminus was fine mapped with newly developed polymorphic markers to characterize the extent of the co
264 ric cancer progression, we used high-density polymorphic markers to screen for LOH in matched normal
265 enome-wide scan of short tandem repeat (STR) polymorphic markers was analyzed for linkage to COPD-rel
267 genomewide scan of short tandem repeat (STR) polymorphic markers was performed in 72 pedigrees (585 i
274 tandem repeat polymorphisms and 2 biallelic polymorphic markers were identified and included as STSs
277 nkage analysis if the appropriate density of polymorphic markers were known and if the genotyping eff
280 ers for known ADC loci and other genome-wide polymorphic markers were used to map the gene; two-point
283 Prism linkage mapping set which includes 350 polymorphic markers with an average spacing of 12 cM.
285 ew map, the Rutgers Map v.2, includes 28,121 polymorphic markers with physical positions corroborated
286 port a zebrafish genetic map comprising 4073 polymorphic markers, with more than twice the number of
287 sity (LOH) during tumor development, another polymorphic marker within GPx-1, which is frequently het
288 using DNA from the family and an intragenic polymorphic marker within the AT3 gene showed that the d
289 78 simplex and 350 multiplex families for 10 polymorphic markers within a genomic interval of approxi
291 mary adenocarcinomas of the ovary for LOH of polymorphic markers within and flanking the PTEN gene an
292 ealthy control subjects were genotyped for 6 polymorphic markers within and near NRAMP1 on chromosome
294 rkers across the MM locus, provided five new polymorphic markers within it and narrowed the locus to
295 to BRCA1, we constructed a haplotype of nine polymorphic markers within or immediately flanking the B
298 zygous for the same allele, for two adjacent polymorphic markers within the region segregating with t