ライフサイエンスコーパス: polyvalent

1 NF-alpha homotrimer enables the formation of polyvalent Ab-TNF-alpha immune complexes (ICs) that enha

2 Previous measurements demonstrate that the polyvalent acidic lipid phosphatidylinositol 4,5-bisphos

3 quely synergistic system with which to study polyvalent adhesion of bacteria to biologically relevant

4 tion of the surface BCR into polarized caps, polyvalent Ag-induced BCR caps persisted.

5 Although both paucivalent and polyvalent Ags induced the redistribution of the surface

6 lent anthranilic acid catalysts operating on polyvalent aldehyde substrates were used with PAMAM dend

7 g of multivalent ligands within a mixture of polyvalent amphiphiles provides, in principle, a simple

8 hesion has been difficult both because it is polyvalent and because bacterial adhesins often recogniz

9 larly, all 21 serum samples were positive in polyvalent and class-specific ELISAs with whole-cell B.

10 -cell biology and provided evidence of their polyvalent and important role in gut homeostasis.

11 IgG1-BCR and IgM-BCR bind preferentially to polyvalent and monovalent antigens, respectively.

12 Polyvalent and Monovalent-89.6) (P = 0.039).

13 Adenosine tripolyphosphate (ATP) is a small polyvalent anion that has recently been shown to interac

14 rophysiology of Bot1 detects Na(+)-dependent polyvalent anion transport in a Nernstian manner with ch

15 The polyvalent anions sulfate and phosphate were found to be

16 g of either flavin mononucleotide (FMNH2) or polyvalent anions.

17 ach, we study the DNA-mediated adsorption of polyvalent anisotropic nanoparticles on surfaces and exp

18 sis of hydrazone ligation were observed when polyvalent anthranilic acid catalysts operating on polyv

19 etection of viral nucleoprotein binding to a polyvalent anti-influenza aptamer by monitoring the surf

20 The results indicate that polyvalent antibodies predominantly directed against V3

21 1D2-Ig alpha tp (abbreviated as D1D2-IgP), a polyvalent antibody construct that presents dodecameric

22 K) cells with a supramolecular aptamer-based polyvalent antibody mimic (PAM).

23 ntinued pneumococcal carriage despite hosts' polyvalent antibody repertoire.

24 Polyvalent antibody responses to a recombinant fusion pr

25 creased, analogous to the precipitation of a polyvalent antigen by divalent antibodies.

26 ell line, or consistent patterns of M. canis polyvalent antigen distribution in canine meningoencepha

27 sm was deconstructed and a minimal composite polyvalent antigen was engineered, delivering a designed

28 ng antigen-specific IgE were aggregated with polyvalent antigen, they became rapidly phosphorylated a

29 is an important determinant of ADCC and that polyvalent antigen-specific Abs are required for a robus

30 as reliant on detergent-mediated exposure of polyvalent antigen.

31 -methionyl-leucyl-phenylalanine and IgE plus polyvalent antigen.

32 recombinant ALVAC vectors represent powerful polyvalent antigenic stimuli for activation and expansio

33 rmed by the cross-linking of antibodies with polyvalent antigens play critical roles in modulating ce

34 B lymphocytes preferentially capture polyvalent antigens, which are capable of eliciting a co

35 was selectively immunoprecipitated by rabbit polyvalent antiserum generated against the predicted uni

36 Our simulations show how polyvalent apical membrane Ag-1 vaccination alters the s

37 We propose that messicles form through a polyvalent assembly mechanism, in which a critical surfa

38 This bias, together with polyvalent attachment to cell surface antigen, would ens

39 However, the correlation between polyvalent avidities and solution affinities is poor.

40 ate ligands in solution correlate with their polyvalent avidities.

41 d when designing new electrode materials for polyvalent batteries.

42 ctions can be stabilized by a combination of polyvalent binding and the enhanced macromolecular crowd

43 Polyvalent binding inhibitors have potential as antivira

44 Polyvalent binding is possible at all surface densities

45 We propose that the polyvalent binding mode characterized for UBXD1-N is a m

46 Here, we examined the role of polyvalent binding of GM(1) in CT action by producing ch

47 RING bodies form polyvalent binding surfaces and scaffold multiple partne

48 s at the pilus tip, which likely facilitates polyvalent binding to pIII proteins at the phage tip.

49 e interactions in a manner characteristic of polyvalent binding.

50 In trivalent (and more generally, polyvalent) binding, dissociation occurs in stages, and

51 Therefore, as a prototype of polyvalent bionanoparticles, TYMV can be used as scaffol

52 The paper demonstrates that polyvalent, biospecific, noncovalent interactions betwee

53 on as well as type of cation (monovalent and polyvalent) can significantly influence thermal stabilit

54 A therapeutic polyvalent cancer vaccine (Canvaxin vaccine; CancerVax C

55 Polyvalent cancer vaccines targeting the entire antigeni

56 The results suggest that monovalent or polyvalent carbohydrate or glycoprotein mimetics that in

57 nition signals in nature, as well as for how polyvalent carbohydrate-protein interactions should be s

58 model systems for cell surfaces to evaluate polyvalent carbohydrate-protein interactions.

59 roach to synthesize solid-phase libraries of polyvalent carbohydrates, one can rapidly address key is

60 ecificity in recognition processes involving polyvalent carbohydrates.

61 creased in the presence of increased aqueous polyvalent cation concentrations or decreased pH.

62 lts indicate that charge neutralization by a polyvalent cation is sufficient to promote formation of

63 We report that the polyvalent cation ruthenium red (RR) directly evokes rap

64 Extracellular calcium/polyvalent cation-sensing receptors (CaR) couple to G pr

65 To determine whether calcium polyvalent cation-sensing receptors (CaRs) are salinity

66 bilize the native fold of RNA, whereas other polyvalent cationic ligands can act to both stabilize or

67 Exposure of HL-60 cells to polyvalent cationic metals results in a dramatic and sus

68 ETH-129 transports polyvalent cations according to the selectivity sequence

69 re we compare the characteristics of several polyvalent cations and Mg(2+) to block monovalent MIC cu

70 , intracellular Mg-nucleotides, divalent and polyvalent cations and pH.

71 Screening negative charges with polyvalent cations antagonized the effect.

72 characteristics and block of MIC channels by polyvalent cations from the outside.

73 Other polyvalent cations had similar effects, including La(3+)

74 We find that polyvalent cations like Ca(2+) and the trivalent cobalt

75 We conclude that polyvalent cations not only alter the net mobility but a

76 vesicle loaded with chelator/indicators for polyvalent cations show that ionomycin transports divale

77 e the unopened phage capsid upon addition of polyvalent cations to the host solution, in agreement wi

78 ot aggregate at low pH or in the presence of polyvalent cations, and can be used to solubilize membra

79 Here we show that Ca2+, or certain other polyvalent cations, binds to an extracellular site on ra

80 example, the bundle formation of F-actin by polyvalent cations, including divalent metal ions such a

81 iments involving intracellular dialysis with polyvalent cations, inhibition of PIP2 synthesis kinases

82 ement with those reported in the presence of polyvalent cations.

83 ing evasins, and use it to identify 10 novel polyvalent CC-chemokine binding evasin-like peptides fro

84 Dog tick saliva contains polyvalent CC-chemokine binding peptides termed evasins

85 The alpha-tosyloxy ketones produced are polyvalent chiral synthons.

86 This study demonstrated that this polyvalent cholera protein is broadly immunogenic and cr

87 cpF should be considered as a component of a polyvalent cholera vaccine formulation.

88 hypothesize how the unique properties of the polyvalent chromatin fiber and associated effectors may

89 These results demonstrate the potential of polyvalent coacervate as a new controlled delivery platf

90 eved robust angiogenesis using an injectable polyvalent coacervate of a polycation, heparin, and fibr

91 Here we report the development of polyvalent complexes of CD1b proteins and carbohydrate b

92 in pathways that involve homo-oligomeric or polyvalent components.

93 ation of the amino group or the synthesis of polyvalent compounds by attachment to an activated polya

94 d to study the interactions of the mono- and polyvalent compounds with XL35.

95 eumococcus in the post-vaccine era, use of a polyvalent conjugated meningococcal vaccine, and influen

96 Combinatorial polyvalent contacts of histone-binding domains or reader

97 hievement of a critical density that permits polyvalent contacts.

98 ween two mechanisms (polyfluoride anions and polyvalent Cs cations) allows CsF2 and CsF4 compounds to

99 decoys, but the structural context of these polyvalent decoys remains unclear, and it has been argue

100 ngly, the animals in the Monovalent-DH12 and Polyvalent-DH12 vaccine groups were more resistant to th

101 nt); (ii) LAI, RF, 89.6, AD8, Bal, and DH12 (Polyvalent-DH12); (iii) 89.6 (Monovalent-89.6); and (iv)

102 The polyvalent display of carbohydrate groups found on cell

103 atalytic properties or as scaffolds enabling polyvalent display.

104 s of enthalpy and entropy in the affinity of polyvalent DNA nanostructure interactions, which exhibit

105 b64, from a human volunteer immunized with a polyvalent DNA prime-protein boost HIV vaccine.

106 ross-subtype ADCC and ADCP activities when a polyvalent DNA prime-protein boost vaccine formulation w

107 ridization in the context of an aggregate of polyvalent DNA-Au NP conjugates occurs in three dimensio

108 aluate safety and immunogenicity of a unique polyvalent DNA-protein HIV vaccine with matching envelop

109 PhLP2A binds to open apo-TRiC through polyvalent domain-specific contacts with its chamber's e

110 ation of a substrate receptor can generate a polyvalent E3 ligase complex and that the internal dynam

111 MTTT 1 used a VlsE1/pepC10 polyvalent EIA followed by a whole-cell sonicate (WCS) p

112 EIA followed by a whole-cell sonicate (WCS) polyvalent EIA.

113 ivity is attributed to the interplay between polyvalent electrostatic and non-covalent interactions t

114 proteins when their association is driven by polyvalent, electrostatic interactions.

115 We attribute these properties to polyvalent engagement between the dendrimer surface grou

116 vaccine phase I trial, the DP6-001 trial, a polyvalent Env DNA prime-protein boost formulation could

117 ein (MBP) fusion peptide, as an antigen in a polyvalent enzyme-linked immunosorbent assay (ELISA).

118 borreliosis, respectively, were analyzed in polyvalent enzyme-linked immunosorbent assays (ELISAs) w

119 tested with human sera in class-specific and polyvalent enzyme-linked immunosorbent assays (ELISAs).

120 ing concentrations of antivenin (Crotalidae) polyvalent (equine origin) and either Crotalus atrox (We

121 ription-translation (TXTL) is expanding as a polyvalent experimental platform to engineer biological

122 ved when the saccharides were presented in a polyvalent fashion.

123 y human volunteers confirms the value of the polyvalent formulation in this HIV vaccine design.

124 Polyvalent, generation 4 (G4) SA-conjugated polyamidoami

125 esting that vaccination schemes that include polyvalent, genetically divergent immunogens may generat

126 val of cell-surface gal-3 from CD45 with the polyvalent glycan inhibitor GCS-100 rendered DLBCL cells

127 The synthesis of polyvalent glycopeptides containing three different anti

128 g the potential for a new mode of action for polyvalent glycopeptides.

129 Unlike lysine, the polyvalent guanidyl group of arginine is capable of both

130 The yeast C-8,7 sterol isomerase contains a polyvalent high-affinity drug binding site similar to ma

131 y, nucleation potential, and low complexity, polyvalent, highly charged nature-could contribute to or

132 t with substrates important for adhesion via polyvalent hydrophobic interactions.

133 Polyvalent ICs and Ab bound to mTNF-alpha on the surface

134 munoglobulin G (IgG)-opsonized particles and polyvalent IgG immune complexes, respectively.

135 Polyvalent IgG replacement therapy might not fully compe

136 ein(s) from (i) LAI, RF, 89.6, AD8, and Bal (Polyvalent); (ii) LAI, RF, 89.6, AD8, Bal, and DH12 (Pol

137 ations of different TLR ligands to stimulate polyvalent immune responses.

138 el skin electroporation microarray can drive polyvalent immunity in macaques, and offers protection f

139 ectively for 2 years while receiving similar polyvalent immunoglobulin replacement therapies.

140 nsisting of perioperative management of DSA (polyvalent immunoglobulins +/- perioperative plasmaphere

141 ed by the greater agglutination potencies of polyvalent immunoglobulins but the bioprocessing ease an

142 ensation mechanisms, and oxidation states of polyvalent impurities in complex multiphase mineral syst

143 at useful concentrations in the presence of polyvalent impurities with lower energy demand and highe

144 thesis that increasing virus input titres in polyvalent inactivated HRV vaccine may result in broad n

145 inst many rhinovirus types can be induced by polyvalent, inactivated HRVs plus alhydrogel (alum) adju

146 can be inhibited by a synthetic, polymeric, polyvalent inhibitor in vivo.

147 Together, our work implies that Eap is a polyvalent inhibitor of NSPs.

148 , we designed monodisperse polypeptide-based polyvalent inhibitors of anthrax toxin in which multiple

149 attern matching also enhanced the potency of polyvalent inhibitors of cholera toxin.

150 f the heterodivalent compounds suggests that polyvalent inhibitors that can target multiple regions o

151 g the valency and linker length, we designed polyvalent inhibitors that were over four orders of magn

152 In the case of the polyvalent interaction between the hexakisBMP25C8 cluste

153 This polyvalent interaction is significantly stronger than th

154 In both instances K(POLY) for the polyvalent interaction was found to be approximately 2 o

155 binding and that BAZ2B PHD-BRD establishes a polyvalent interaction with H3K14ac.

156 By determining K(AVE) for the polyvalent interaction, it was possible to calculate an

157 Most processes of life are the result of polyvalent interactions between macromolecules, often of

158 interactions are strengthened by pronounced polyvalent interactions catalyzed by the surface itself.

159 ty of nanorods originate from the balance of polyvalent interactions that favor adhesion and entropic

160 argely been dependent on engineering similar polyvalent interactions to enable effective targeting.

161 5 free cysteine residues could contribute to polyvalent interactions with the Ag clusters and serve a

162 chieved by means of nonspecific low-affinity polyvalent interactions.

163 , along with my decade-long involvement with polyvalent iodine chemistry, especially alkynyliodonium

164 ordinate, I(III), and pentacoordinate, I(V), polyvalent iodine compounds have been known for over a c

165 In the last twenty years, new polyvalent iodine reagents have been introduced along wi

166 e, an increase in retention was observed for polyvalent ions.

167 Stimulation of mast cells with immobilized polyvalent ligand resulted in typical levels of degranul

168 f the basement membrane and is known to be a polyvalent ligand, possessing sequences bound by the alp

169 fically, high molecular weight, polydisperse polyvalent ligands are effective inhibitors of Con A bin

170 egrin CR3 that requires divalent cations and polyvalent ligands for activation of the receptor.

171 The widespread occurrence of flexible polyvalent ligands in biological systems suggests that t

172 the interaction of polyvalent receptors with polyvalent ligands-in unnatural systems is outlined.

173 tenin and actin, and together they provide a polyvalent linkage directing the topographic assembly of

174 ), MARCKS-(151-175), laterally sequester the polyvalent lipid PI(4,5)P2 in the plane of a bilayer mem

175 Pattern-matched polyvalent liposomes inhibited anthrax toxin in vitro at

176 ract with carbohydrate-binding proteins in a polyvalent manner.

177 change approach for preparing compact, dense polyvalent mannose-capped quantum dots (QDs) has been de

178 dy (sdAb) that is both captor and tracer for polyvalent Marburgvirus nucleoprotein.

179 An allogeneic polyvalent melanoma cell vaccine (PMCV) has been shown t

180 Wayne Cancer Institute, Santa Monica, CA), a polyvalent melanoma cell vaccine (PMCV), might be correl

181 observed in melanoma patients treated with a polyvalent melanoma cell vaccine containing TRP-2.

182 pigmentation and had improved survival after polyvalent melanoma cell vaccine had significantly augme

183 receiving postoperative immunotherapy with a polyvalent melanoma cell vaccine increased sensitivity a

184 Polyvalent melanoma cell vaccine treatment enhanced anti

185 in melanoma patients (n = 23) pre- and post-polyvalent melanoma cell vaccine treatment.

186 anic matter (NOM) via thiol coordination and polyvalent metal cation-bridged ternary complexation.

187 The potential for ligand bridging by polyvalent metal ions is proposed to be an important fac

188 ise energy efficiency and poor tolerance for polyvalent metal ions that complicates applications invo

189 ically diverse cations including dendrimers, polyvalent metals, metal complexes, amphiphiles, and alk

190 with OzID for exemplary lipids cationized by polyvalent metals.

191 Thus, a polyvalent, minigene-based vaccine can simultaneously in

192 e as models to study the binding behavior of polyvalent molecules and gain insight into how small cha

193 f liposomal surfaces as well as detection of polyvalent molecules and removal of targeted substances

194 tegy for the rational design of monodisperse polyvalent molecules may not only be broadly applicable

195 The design of polyvalent molecules, presenting multiple copies of a sp

196 ivity relationships and for designing potent polyvalent molecules.

197 Polyvalent mosaic antigens therefore represent a promisi

198 Polyvalent mosaic HIV immunogens offer a potential solut

199 Polyvalent mosaic immunogens derived by in silico recomb

200 ne constructs expressing either consensus or polyvalent mosaic proteins.

201 Polyvalent 'mosaic' antigens, in contrast, are designed

202 intermolecular cross-links among the arrayed polyvalent mucin mimetics.

203 Assembling nanobodies (Nbs) into polyvalent multimers is a powerful strategy for improvin

204 Here, we created a new polyvalent nanobody (Nb) structure that shows the effect

205 The polyvalent nature of nucleocapsid borne NP and display o

206 Our polyvalent Nb structure, called "PNS", is achieved by fi

207 ine targeted muscle reinnervation surgery of polyvalent nerves with a high-density microelectrode arr

208 ism of alpha-toxins prevents production of a polyvalent neutralizing antiserum, whereas the determina

209 These findings indicate that polyvalent neutralizing MAb formulations targeting epito

210 is Communication, we describe a new class of polyvalent nucleic acid nanostructures (PNANs), which ar

211 ntibody clone was both captor and tracer for polyvalent nucleoprotein (NP).

212 Polyvalent O and O1 antiserum sensitivity and specificit

213 specificity were >90%, with the exception of polyvalent O1 antiserum, for which sensitivity was 88.9%

214 of the pattern-recognition ability of these polyvalent oligomers.

215 Amine-functionalized polyvalent oligonucleotide gold nanoparticles (DNA-Au NP

216 for human telomerase activity that relies on polyvalent oligonucleotide nanoparticle conjugates as di

217 Polyvalent oligonucleotide-nanoparticle conjugates posse

218 Enhanced inhibitory potencies of polyvalent over monovalent forms of oligosaccharide inhi

219 inding selections using FcepsilonRIalpha and polyvalent peptide-phage libraries yielded a dominant 18

220 oponin I (TnI), previously identified from a polyvalent phage displayed library, has been immobilized

221 agnitude higher than that calculated for the polyvalent phage particles (K(D) = 2.5 +/- 0.1 nM).

222 Here we compare the efficacy of polyvalent phage PEf1 versus coliphage T4 in suppressing

223 Overall, this study shows that polyvalent phages can propagate in soil bacteria and sig

224 Polyvalent phenylboronic acid-labeled bovine serum album

225 mportant PM lipids including cholesterol and polyvalent phosphoinositides, further demonstrating PS s

226 tibody concentrations were immunised with 23 polyvalent pneumococcal and tetanus-haemophilus conjugat

227 king oligosaccharyltransferase to generate a polyvalent pneumococcal bioconjugate vaccine with polysa

228 acterial polysaccharides used to formulate a polyvalent pneumococcal polysaccharide vaccine.

229 ide powders to be used in preparation of the polyvalent pneumococcal vaccine PNEUMOVAX 23.

230 disease, and both types are included in the polyvalent pneumococcal vaccine.

231 l P-selectin inhibitors were created using a polyvalent polymer nanoparticle capable of displaying mu

232 ver, because the derivatized beads mimic the polyvalent presentation of cell surface carbohydrates, t

233 rabbits immunized intramuscularly with this polyvalent protein immunogen developed antibodies to all

234 tigen vaccinology platform, we constructed a polyvalent protein immunogen that presents antigenic dom

235 signal transduction methods for detection of polyvalent proteins have been developed by directly coup

236 barcodes, one can screen for multiple target polyvalent proteins simultaneously in one solution.

237 erpesvirus 1 (BHV-1) gI and gE proteins with polyvalent rabbit serum specific for gI or gE.

238 the study of polyvalency-the interaction of polyvalent receptors with polyvalent ligands-in unnatura

239 Moreover, these polyvalent responses proved to be tumor-suppressive and

240 ev molecules, it would be useful to generate polyvalent Rev decoys that could bind multiple Rev molec

241 . A. Sharp originally constructed functional polyvalent Rev decoys, but the structural context of the

242 Furthermore, treatment of cells with polyvalent RGD peptides or pre-polymerized fibronectin d

243 report the synthesis and characterization of polyvalent RNA-gold nanoparticle conjugates (RNA-Au NPs)

244 ble than mG RSV to monovalent G-specific and polyvalent RSV-specific antibodies, whereas susceptibili

245 We have reported that polyvalent SA attachment induces lysis of biotinylated R

246 in polyvalent salt solutions at small enough polyvalent salt concentrations.

247 ced expanded --> condensed DNA transition in polyvalent salt solutions at small enough polyvalent sal

248 A solutions for monovalent salts to that for polyvalent salts and sheds some light on the complicated

249 n effort to mimic the high-affinity binding, polyvalent scaffolds that contain multicomponent display

250 mbly creates bodies that act structurally as polyvalent scaffolds, thermodynamically by amplifying ac

251 The relative capacity of murine polyvalent sera produced following infection, recovery,

252 igen argue for the inclusion of rCFP-10 in a polyvalent serodiagnostic test for detection of active T

253 n the surface of Gram-negative bacteria into polyvalent signaling platforms required for activation o

254 n be evaluated for glycan interactions using polyvalent soluble glycan probes and for protein interac

255 mblies can be modulated between bivalent and polyvalent states.

256 A stable polyvalent STING agonist or p53 induction increases sens

257 Here, we show that a polyvalent STING agonist-a pH-sensitive polymer bearing

258 concatenated conserved protein regions, and polyvalent strategies that improve coverage of epitope d

259 The avidities of polyvalent sugar-coated virus particles for immobilized

260 sure) liquid chromatography was applied to a polyvalent system composed of both reactive and nonreact

261 y, we show that trifunctional bsAbs induce a polyvalent T-cell response and, therefore, a vaccination

262 able, but reversible specific recognition of polyvalent targets.

263 ker region also bind with higher affinity to polyvalent than monovalent phosphoinositides on nitrocel

264 cal pattern matching enhances the potency of polyvalent therapeutics.

265 tumor cell destruction in situ may provide a polyvalent tumor vaccine without a requirement for knowl

266 Our data provides information supportive of polyvalent vaccination approaches capable of inducing V2

267 ll affinity maturation during monovalent and polyvalent vaccinations that predicts the fine specifici

268 eive Canvaxin (CancerVax Corp, Carlsbad, CA) polyvalent vaccine (PV) immunotherapy for metastatic mel

269 ant.Our results indicate that an inactivated polyvalent vaccine against RABV filoviruses is achievabl

270 We have designed new polyvalent vaccine antigens comprised of sets of 'mosaic

271 his approach to predict the Ab response to a polyvalent vaccine based on the highly polymorphic malar

272 d HLA-A*02+ melanoma patients immunized to a polyvalent vaccine containing multiple Ags, including MA

273 ty, and outline the rationale behind several polyvalent vaccine design strategies that are currently

274 on, diagnostics, surveillance and ultimately polyvalent vaccine development.

275 , globo H will constitute one component of a polyvalent vaccine for evaluation in high-risk breast ca

276 bsence of any detectable NAb, animals in the Polyvalent vaccine group, but not those immunized with M

277 Animals in the two polyvalent vaccine groups developed NAbs against more HI

278 ns failed to elicit neutralizing antibodies, polyvalent vaccine immunization induced neutralizing res

279 NTHI-mediated otitis media, development of a polyvalent vaccine reflecting the variability of P1 woul

280 for continued clinical investigation of this polyvalent vaccine strategy in the treatment of metastat

281 The development of a polyvalent vaccine targeted against the most pathogenic

282 virus type 1 (HIV-1), it is probable that a polyvalent vaccine will also be needed for protection fr

283 o a broad array of HIV-1 primary isolates, a polyvalent vaccine will be needed containing representat

284 rain-specific epitopes and demonstrate how a polyvalent vaccine with a small number of strains and on

285 However, to understand how to construct a polyvalent vaccine, serotypes or immunotypes of HIV must

286 We also demonstrated that in a polyvalent vaccine, where both forms of the same epitope

287 immunogen and similar T-cell responses to a polyvalent vaccine.

288 cell-mediated immune response induced by the polyvalent vaccine.

289 that exhibit significant genetic variation, polyvalent vaccines are needed.

290 Polyvalent vaccines may therefore be required to provide

291 Polyvalent vaccines use a mixture of Ags representing di

292 eadjustment using current variant sequences, polyvalent vaccines, or pan-coronavirus strategies.

293 than genotypic classification for designing polyvalent vaccines, studies were undertaken to determin

294 ral or microbial species in order to develop polyvalent vaccines.

295 oss-reactivity may be a universal feature of polyvalent vaccines.

296 iants that should be included or excluded in polyvalent vaccines.

297 in animals immunized with monovalent versus polyvalent vaccines.

298 nesis that results from treatment with these polyvalent VEGF-mimetic nanofibers.

299 he safety, activity, and immunogenicity of a polyvalent Wilms tumor gene 1 (WT1) peptide vaccine in p

300 These preliminary data suggest that this polyvalent WT1 peptide vaccine can be administered safel