ライフサイエンスコーパス: pool

1 y of genetic variability in the primary gene pool.

2 contributes to the soil organic carbon (SOC) pool.

3 en up an untapped and highly diverse subject pool.

4 hosphorylation than the coreceptor-bound Lck pool.

5 sediments that remove iron from the soluble pool.

6 e greater than the conventional exchangeable pool.

7 differentiation and maintain the prohemocyte pool.

8 ROS buildup and oxidation of the nucleotide pool.

9 of cholesterol to an esterified cholesterol pool.

10 ivision to repopulate the vascular stem cell pool.

11 e exhaustion of the quiescent satellite cell pool.

12 lar reactions that directly engage the arene pool.

13 tly differ from those within uninjured motor pools.

14 that require expansion of guanine nucleotide pools.

15 e and draws upon large and diverse substrate pools.

16 nd on the initial strategy to form heterotic pools.

17 ilitated the efflux of intracellular leucine pools.

18 r tooth in each quadrant, were harvested and pooled.

19 The pooled 1-, 3-, and 5-year RFS rates were 70% (95%CI: 63%

20 Pooled 5-year survival estimates were 3% (95% CI 1-5%; n

21 recognized within the murine satellite cell pool, a comprehensive understanding of distinct subpopul

22 ubpopulations are undetectable when data are pooled across the gradient.

23 INR) fail to reconstitute their CD4 + T cell pool after initiation of antiretroviral therapy, and the

24 Pooled anal HPV16 prevalence was 3.6% (95% CI, 1.6%-7.8%

25 Pooled analyses after adjustment for study design found

26 Pooled analysis of RH cells showed high power and resolu

27 hial rheoplasty in patients with CB.Methods: Pooled analysis of two separate studies enrolling 30 pat

28 th only nCLCb had a reduced synaptic vesicle pool and impaired neurotransmission compared to WT mice,

29 show that repeated mating reduced the sperm pool and increased the percentage of GSCs in M- and S-ph

30 gradients could result from regional species pool and local community assembly mechanisms.

31 ves oxidized nucleotides from the nucleotide pool and thereby prevents their incorporation into the g

32 orted to impact a small fraction of the tRNA pool and thus presumed to not directly impact translatio

33 se 1/2A cell therapy group (CTG) trials were pooled and analysed, in which patients received one of s

34 The effects of pooled and recombinant human tryptases, protease activat

35 cluded on patient reports, (iii) if specimen pooling and testing by research staff represent acceptab

36 anthropogenic water diversions, natural step-pools and cascades in steeper upstream reaches.

37 cells (HSC) self-renew to sustain stem cell pools and differentiate to generate all types of blood c

38 n species based on estimated sizes of source pools and dynamics of historical invasions, assuming a c

39 Soil carbon (C) pools and plant community composition are regulated by n

40 Uptake in the AVM, blood pool, and muscle was quantified as SUV(max) and SUV(peak

41 The checklist tool and pooling approach described can be used in a variety of t

42 e acids(4); the size and composition of this pool are a target of therapies for primary biliary chola

43 to track and categorise how ATP and NAD(P)H pools are affected in the presence of a new pathway.

44 nging environments, and that both functional pools are distinctly regulated.

45 gher local richness not simply because older pools are more speciose but also because species have ev

46 For selection of novel functions the pools are typically transcribed from random-sequence DNA

47 ssembled into metabolons and which substrate pools are used by each is still not well understood.

48 Data were pooled as odds ratio (OR) or mean difference (MD) with a

49 Partitioning of this local pool at each cell division modulates nuclear growth kine

50 ratios of at least 2.11 for lesion to blood pool, at least 0.55 for lesion to liver, and at least 4.

51 The resulting conformer pools balance goodness-of-fit with ligand strain.

52 ay not only affect soil organic carbon (SOC) pool but also impact SOC stability through soil aggregat

53 t only because of differences in the species pool, but also because the same species have different d

54 represent a possible expansion to the donor pool, but are frequently discarded as they are associate

55 nisovan DNA persist in the modern human gene pool, but have been systematically purged by natural sel

56 are recruited and fully replenish the docked pool, but this docking is transient and they either undo

57 EFF), T circulating memory (TCIRCM), and TRM pools by lineage-tracing and single-cell transcriptome a

58 (DHODH) with leflunomide impacts nucleotide pools by reducing pyrimidine levels.

59 y because oxidized purines in the nucleoside pool can significantly contribute to genetic instability

60 % concordance with the expected results, and pooled clinical specimens had standard deviations and co

61 addition of the polygenic risk score to the pooled cohort equations did not provide significant impr

62 general CVD 1991 and 2008 equations and the Pooled Cohort equations for atherosclerotic CVD within f

63 CAD discrimination for polygenic risk score, pooled cohort equations, and both combined resulted in C

64 f Cardiology/American Heart Association 2013 pooled cohort risk equation.

65 By bridging split-and-pool combinatorial synthesis with the ligation of unique

66 er contribution of African women to the gene pool compared to African men varies across the Americas,

67 ields and associated carbon input to the SOC pool counteracted the increased decomposition in the ada

68 to researchers on the design and analysis of pooled CRISPR screens.

69 ty of our approach to facilitate image-based pooled CRISPR screens.

70 Using pooled CRISPR-Cas9 knockout screens, we showed that tera

71 We pooled cross-sectional data from the 2004 to 2017 Nation

72 esult of low background levels, barcoded and pooled CUT&Tag libraries can be sequenced for as little

73 Pooled data analysis in the field of maternal and child

74 We used pooled data from an international collaboration of prosp

75 Using DNA barcoding and split-pool decoding, we created a large library of isogenic re

76 impact of these contributions on nucleotide pools depends on the degree to which the membrane compet

77 ean gestational age, 37.8 weeks) walked in a pool (depth 1.3 m) for 1 h.

78 n the heterogeneous leukemia stem cell (LSC) pool determine aggressiveness of acute myeloid leukemia

79 gions of the extracellular and bath or blood pool directly in contact with electrodes that exhibit a

80 ranules (SGs) exist in functionally distinct pools, displaying variations in motility as well as dock

81 ysis of qPCR amplicons to monitor changes in pool diversity and sequence enrichment.

82 pecies (ROS) oxidize nucleotide triphosphate pools (e.g., 8-oxodGTP), which may kill cells if incorpo

83 This prespecified analysis pooled efficacy data through the first 48 weeks of DRIVE

84 ons by combining DNA barcoding, unique split-pool encoding, and single cell expression measurements.

85 We found that BA pools, especially those low in 12HBAs, induce cellular m

86 There is a wide variation of pooled estimated mean content of CLA in milk among the s

87 However, the pooled estimated mean of AFM1 levels in milk were 94.58

88 The pooled estimates (percentage changes) of mortality from

89 s for a specific health outcome and assessed pooled estimates for each lag when at least three studie

90 The interpretation of pooled estimates is limited by the considerable between-

91 assay underwent four validation studies with pooled estimates of sensitivity (84.8%; 95% confidence i

92 oled prevalence for each Clinical (C) stage; pooled estimates were: C0 s: 9%, C1: 26%, C2: 19%, C3: 8

93 its strong capacity to expand memory T-cell pool exhibiting effector memory T-cell phenotype, theref

94 odel accurately reproduces LC11 responses by pooling fast-adapting, tightly size-tuned inputs.

95 ively reducing the available monomeric Abeta pool for incorporation into fibrils.

96 an agronomically and nutritionally important pool for rice improvement/breeding.

97 Sham arms were pooled for analysis.

98 An international sample, pooled from 9 medical centers across Europe, the United

99 ccounted for by a model with uniform spatial pooling from scale invariant inputs.

100 We pooled genital sub-studies from 2 clinical trials in thi

101 oxidation (redox) changes in the glutathione pool (GSH), glutaredoxins (GRX) and thioredoxins (TRX) a

102 Delayed or defective recovery of the T cell pool has significant clinical consequences, including pr

103 all-cause mortality (13 studies, n = 36 986; pooled hazard ratio [HR], 0.40 [95% CI, 0.28-0.56) and h

104 al T(RM) cells that rejoined the circulating pool, heritably maintained a predilection for homing bac

105 fter adjusting for potential covariates, the pooled HR for the highest compared with the lowest quint

106 rovided data on overall survival (OS) with a pooled HR of 1.91 (95% CI: 1.34, 2.73), indicating that

107 ocellular carcinoma (20 studies, n = 84 491; pooled HR, 0.29 [95% CI, 0.23 to 0.38]) vs no SVR.

108 pared with participants in the lowest score (pooled HR: 0.72, 95% CI: 0.59, 0.87; P value for trend <

109 Undiluted pooled human serum (HS) and five different commercial pr

110 IVIG preparations consisting of pooled IgG are increasingly used for the treatment of au

111 depletion of the oligodendrocyte progenitor pool in MS adults.

112 on of DCD in FHF could help expand the donor pool in this subset of critically ill patients.

113 H isoform in high AVS HNSCC depleted the CIC pool in vitro and in vivo.

114 form, in which 30 isogenic disease lines are pooled in a single dish and differentiated into prefront

115 and trace the soil phases that support these pools in 143 individual soil samples covering 3 climatic

116 64, respectively) at 3 and 18 months of age (pooled) in girls.

117 We pooled individual patient data from the Virtual Internat

118 e results imply that the human visual system pools information about surface tilt across space in acc

119 hes-both at the individual species level and pooled into cold- and warm-edge assemblages-in a multi-d

120 ation, changes in 3-year average annual IRs (pooled IRs from 2000 to 2002 vs. those from 2014 to 2016

121 ) ratio of more than 2.2 for lesion to blood pool is a reasonable parameter to support image interpre

122 How the tRNA(Glu) pool is distributed between the two pathways and whether

123 level data also confirm that the metacyclic pool is diverse, and that each parasite expresses only o

124 tive in preventing T2D; however, the at-risk pool is large, and a clinically meaningful metric for ri

125 We show that the niche cell pool is not only replenished by hemocyte integration but

126 PI4P from multiple pools is delivered to Sac1 by oxysterol-binding protein

127 ese efflux and that Slc30a10 induction by BA pools is driven primarily by lithocholic acid signaling

128 ining single-cell transcriptome analysis and pooled knockin screening to measure cell abundance and c

129 We further developed pooled knockin sequencing (PoKI-seq), combining single-c

130 lack of knowledge about the potential donor pool, lack of robust outcomes data, lack of standard don

131 A reduced SHF progenitor pool leads to an underdeveloped right ventricle (RV) and

132 Pooled library CRISPR/Cas9 knockout screening across hun

133 re, we introduce microSPLiT (microbial split-pool ligation transcriptomics), a high-throughput scRNA-

134 targeting the expanded cytosolic labile iron pool (LIP) of the cancer cell.

135 This directional pooling may potentially affect BOLD linearity across cor

136 -0.11 and -0.64, p = 0.04), and CPFQ scores (pooled mean difference -1.9; Cohen's d for Stages 1 and

137 .43, 95% CI: 0.32-0.59), and length of stay (pooled mean difference -2.01, 95% CI: -2.99 to 1.14).

138 ose showed greater overall reduction in SDQ (pooled mean difference -8.2; Cohen's d for Stages 1 and

139 Pooled means and prevalences were estimated for lipid bi

140 ively for Ca, Mg and K), the plant-available pools measured by isotopic dilution were greater than th

141 and are currently impossible to screen with pooled methods.

142 By combining laboratory incubation and a two-pool model, we then explored changes in soil labile and

143 model were compared to data from individual pooled mutant experiments to identify areas of the model

144 bes findings of novel coronavirus testing on pooled nasopharyngeal and bronchoalveolar lavage samples

145 eason of SARS-CoV-2 and add to the knowledge pool necessary for postpandemic preparedness for SARS-Co

146 he question remains exactly how such surplus pooling occurred and when such traditions were elaborate

147 The pooled odds ratios were 2.15 (95% CI=1.58, 2.94) and 2.0

148 Overall, 63 full texts were assessed from a pool of 652 abstracts.

149 test results) compared with a representative pool of 87 specimens submitted for COVID-19 testing.

150 e acyltransferase selects from the bacterial pool of acyl-acyl carrier proteins (ACPs) an acyl chain

151 ent cross-compartment exchange of a standing pool of amino acids which is used to regulate the proton

152 es that likely shaped the mitochondrial gene pool of ancient Umbri over time, since early Neolithic,

153 Sunlight depleted the pool of aromatic compounds that supported microbial grow

154 he dendritic arbor of neurons constrains the pool of available synaptic partners and influences the e

155 es are major components of the recirculating pool of bile acids(4); the size and composition of this

156 gainst biological threats and broadening the pool of bioaerosol knowledge.

157 The extent of this poorly ionizable pool of carbon is unknown, is presumably variable betwee

158 ears have shown that HIV persists in a small pool of cells harboring integrated and replication-compe

159 within the ER, also called the ER regulatory pool of cholesterol.

160 of protein homeostasis wherein a sacrificial pool of collagen maintains tissue function.

161 orm mediation analysis with a high-dimension pool of covariates.

162 links MAD1 to the corona, and this specific pool of MAD1 is needed to generate a robust SAC response

163 However, if a pool of models are not available, methods that only need

164 g selects full-length HIV-1 RNA from a large pool of mRNAs as virion genome during virus assembly.

165 ates of the DMT-induced altered state from a pool of participants receiving DMT and (separately) plac

166 We tested a pool of Persian speaking subjects with a simple color ma

167 ical projection neurons arise from a uniform pool of progenitor cells that lines the ventricles of th

168 ective concept reported so far is based on a pool of randomly oriented, light-harvesting donor molecu

169 Syt7 mutants also had a larger pool of readily-releasable vesicles, faster recovery fol

170 oString and qRT-PCR for 18 genes in the same pool of RNA (RNAlater), we found a significant correlati

171 We further show that the centromeric pool of SET on Sgo2 depends on Bub1 kinase activity, and

172 The designed pool of siRNAs can be used to construct a long double-st

173 cally connected and communicate through this pool of solutes.

174 how that low-severity fires can increase the pool of stable soil carbon by thermally altering the che

175 ation of bile acids, which creates a complex pool of steroids(8) with a range of physiological functi

176 hment, and increasing the readily releasable pool of synaptic vesicles.

177 A) and a previously unidentified cytoplasmic pool of the reductase Mxr2 (MsrB).

178 tion of stage 3 AKI donors, may increase the pool of viable kidneys.

179 Due to pooling of 3 cohorts and thus the availability of only a

180 ized analysis across these 2 tracers enables pooling of TSPO PET data across multiple centers and inc

181 lution assay to quantify the plant-available pools of calcium, magnesium and potassium and trace the

182 In this study, we tested pools of epitopes derived from dengue (DENV), Zika (ZIKV

183 guanine nucleotides, impacting the cellular pools of GMP, GDP and GTP.

184 e protocols were evaluated on four different pools of human feces.

185 s, and we here present evidence that the two pools of Lck have different molecular properties.

186 characterization of differentially modified pools of tubulin from Tetrahymena thermophila.

187 tations are accompanied by increased sensory pooling onto interneurons as well as species-specific ce

188 ,686 FGM/C and 3,482 non-FGM/C participants; pooled OR: 1.43; 95% CI: 1.17-1.75; I2: 0%; p-value = 0.

189 341 FGM/C and 39,260 non-FGM/C participants; pooled OR: 1.89; 95% CI: 1.26-2.82; I2: 96%; p-value < 0

190 ,516 FGM/C and 8,060 non-FGM/C participants; pooled OR: 2.04; 95% CI: 1.27-3.28; I2: 90%; p-value < 0

191 ,283 FGM/C and 3,382 non-FGM/C participants; pooled OR: 2.47; 95% confidence interval [CI]: 1.45-4.21

192 ,898 FGM/C and 4,229 non-FGM/C participants; pooled OR: 2.63; 95% CI: 1.35-5.11; I2: 67%; p-value = 0

193 Cost reductions can be achieved by pooling (or combining) subsamples and testing them in gr

194 ide-ranging exploratory data analysis (EDA), pooling our original data with extant data from two foll

195 The pooled overall recurrence rate was 43% (95%CI: 33%-53%)

196 Similar patterns were found for pooled persistence by agent.

197 ted FIX in buffer and initiated TG in normal pooled plasma, as well as FXII- or FXI-deficient plasma,

198 spectively, and in 35 (3.9%) patients in the pooled population.

199 re of mutation compared with others based on pooled prevalence analysis.

200 Pooled prevalence estimates were calculated for depressi

201 19 studies were included in the overall pooled prevalence for each Clinical (C) stage; pooled es

202 The pooled prevalence indices of signal transduction pathway

203 st frequent adverse event was fatigue with a pooled prevalence of 16% (95% CI 5-29%), followed by ane

204 The pooled prevalence rates for mental disorders among FSWs

205 The pooled proportion for grade 3-4 cardiovascular adverse e

206 For heart failure, the pooled proportion, based on 38 studies (n=5936 patients)

207 a and 4.8% (4.2%-5.1%) in Dallas-Fort Worth (pooled rate 3.1%).

208 Pooled reductions of SBP were -4.38 mm Hg (95% CI, -7.27

209 ies on the concurrent analysis of calibrated pooled reference samples at predefined intervals and ena

210 Pooled relative risks (RRs), standard mean differences o

211 ted random-effects meta-analysis was used to pool reported estimates, and meta-regression was used to

212 Pooled reported annualized incidence rates of MACE in th

213 In this paper, we draw on common-pool resource theory to argue that indigenous territorie

214 youth (n = 17 811) were highly variable; the pooled result did not show a clinically important or sta

215 The pooled result from two studies conducted in Sweden and T

216 Resequencing of chemotypically extreme pools revealed a known cannabinoid synthesis pathway loc

217 8 incident T2D cases), for each 1 egg/d, the pooled RR of T2D was 1.07 (95% CI: 0.99, 1.15; I2 = 69.8

218 crease in the size of the readily releasable pool (RRP) of synaptic vesicles, consistent with the iso

219 Pooled RRs comparing extreme categories of dietary LA in

220 The pooled sample included 252 745 women (median age at base

221 routine respiratory virus testing to see if pooling samples could increase testing throughput and ef

222 V-2 remnant patient specimen was spiked into pooled SARS-CoV-2 RNA-negative specimen remnants for the

223 ow activity and the lack of a well-validated pooled screening toolkit.

224 guidance on how to design and analyze CRISPR-pooled screens.

225 espective N flows of 728 and 617 mg/8 h (+/- pooled SD: 144 mg/8 h).

226 The pooled sensitivity (95% CI) from the laboratory evaluati

227 Pooled sensitivity and specificity (95% CI, inconsistenc

228 tion was the most-studied instrument, with a pooled sensitivity of 0.89 (95% CI, 0.85 to 0.92) and sp

229 ental testing, the sensitivity improved to a pooled sensitivity of 97.0% (94.8-98.6%).

230 The pooled sensitivity, specificity, and area under the rece

231 Continuous loading of a dynamic cohesin pool separates sister-chromatid pairs inside TADs and is

232 We then used Pool-seq to compare nuclear allele frequencies for high-

233 Nonetheless, pooled sera from pre- and postchallenge groups, but not

234 during drought but also highlight that some pools serve as refuges even under extreme drought condit

235 The free Lck pool showed more activating Y394 phosphorylation than th

236 ral maintained homeostasis in their nutrient pools, showing tolerance to the different nutrient regim

237 eletal muscle cells using RNA-seq of subtype-pooled single human muscle fibers and single cell RNA-se

238 BA pool size and composition are affected by changes in met

239 ed qPCR-based analyses to evaluate the ssDNA pool size and remelting curve analysis of qPCR amplicons

240 osis is coupled to exocytosis to maintain SV pool size and thus neurotransmitter release.

241 y-dependent augmentation of synaptic vesicle pool size relies exclusively on the action of Munc13s.

242 ly reduced postoperative opioid requirement (pooled SMD -0.31 [95% CI -0.45 to -0.16], P < 0.001, I =

243 gnificantly reduced intraoperative propofol (pooled SMD -0.72 [95% CI -1.01 to -0.43], P < 0.00001, I

244 = 61.1, N = 554) and midazolam requirement (pooled SMD -1.07 [95% CI -1.70 to -0.44], P < 0.001, I =

245 Aromatic hydrocarbon pool species severely hinder the diffusion and their spa

246 uations (n = 5) was 98.5% (92.1-100%), while pooled specificity was 95.9% (81.5-100.0%).

247 Pooled specimens missed 2 NG and 11 CT infections, where

248 ts meta-analyses were carried out generating pooled standardized mean differences (SMDs).

249 effective use of (-)-quinic acid as a chiral pool starting material and substrate stereocontrol to es

250 ratories have recently published examples of pooling strategies applied to SARS-CoV-2 specimens, but

251 specimens, but overall guidance on efficient pooling strategies is lacking.

252 The current study describes a pooling strategy based on identification of sociodemogra

253 The variation in several metabolite pools such as malate, fumarate or citrate, and flux calc

254 ced retention of human centromeres in the RH pools suggests a new approach to functional dissection o

255 A mildly lower blood pool SUL(mean) was observed after MSG administration (de

256 Meta-analysis was performed to pool survival estimates, accounting for trends over time

257 Our results not only suggest that many pools sustain juvenile salmon in non-drought years trans

258 in complex with complement component C4d in pooled synovial fluid of rheumatoid arthritis (RA) patie

259 We hope that such implementation of a pool test for coronavirus disease 2019 would allow expan

260 ability generates acoustic waves in the melt pool that provide additional yet vital driving force for

261 voided close kin unions despite limited mate pools that reflect small effective population sizes, whi

262 The data were insufficient to pool the results for waist-to-hip ratio (WHR) and waist-

263 on to l-cysteine depleted both NADPH and GSH pools, thereby allowing toxic accumulation of reactive o

264 d 95% CIs were estimated in each dataset and pooled through fixed-effects meta-analysis.

265 a large fraction of the iron-binding ligand pool throughout the water column.

266 estricted presentation of endogenous TRP1 by pooled thymic APCs.

267 n enables rapid mobilization of this protein pool to protect exposed ssDNA and repair genomic loci af

268 of distance from the inner central canal CSF pool to the outer subpial surface.

269 3 different centers (n = 27, 29, and 8) were pooled to constitute the training set, whereas the patie

270 Data pooling to increase the confidence in the discovered mut

271 combine protein side chains in these contact pools to generate hundreds of thousands of energetically

272 olarized cholangiocytes release distinct sEV pools to mediate communication via their apical and baso

273 d, in response, decreasing excess spermidine pools to normal levels.

274 nowlesi, in part because the extent to which pooled transfections can be performed in these species r

275 dium berghei and Toxoplasma gondii, in which pooled transfections of multiple vectors were critical t

276 cts meta-analysis models were used to report pooled treatment effects and CIs.

277 The pooled treatment effects showed consistent benefits for

278 orms the average individual, we test whether pooling treatment durations recommended by different pre

279 defined humic, fulvic, and hydrophilic acid pools under various extraction conditions, and subsequen

280 p analysis according to management yielded a pooled upgrade rate of 29% (95% confidence interval [CI]

281 lls may contribute to the serum HLA antibody pool upon antigen reexposure.

282 Hedges' g coefficients were pooled using 3-level random-effects meta-regression.

283 The ORs from each study were pooled using an inverse-variance-weighted random-effects

284 Estimates of FH prevalence were pooled using random-effects meta-analyses and were 0.32%

285 Individual survey odds ratios (ORs) were pooled using random-effects meta-analysis.

286 Multivariable-adjusted RRs were pooled using random-effects meta-analysis.

287 Percentage change in BMD was pooled using random-effects models and reported as weigh

288 Data from eligible studies were pooled using standardised methodology.

289 Pool walking may improve renal function in pregnant wome

290 nsin-aldosterone level was suppressed during pool walking: the mean starting and ending values of pla

291 ntually returned to normal, the expanded NSC pool was maintained in the V-SVZ until old age.

292 Meta-analytic pooling was not possible due to variations in study desi

293 0 Dalton had the highest activity, and these pools were analysed by mass spectrometry in order to ide

294 fication were tested and the tryptic peptide pools were analysed by untargeted high resolution tandem

295 The highest mean soil C and N pools were found in grazed and fertilized plots.

296 erentiated astrocytes restrict the stem cell pool with age.

297 ontaminant from a large scale of contaminant pool with high prediction accuracy, but we can also iden

298 resents a non-negligible highly labile metal pool with important potential for contrasting isotopic f

299 king result was an increase in the number of pools with reduced or zero survival during drought years

300 n programs in the human CD8(+) memory T cell pool, with potentially broad implications for the develo