ライフサイエンスコーパス: portal

1 , a new open-access microbial bioinformatics portal.

2 comprehensive, user-driven variant analysis portal.

3 s of Living Australia, including its spatial portal.

4 ivery of data through a knowledge management portal.

5 n and presents it in a central, feature-rich portal.

6 and provide these data through a public web portal.

7 pen and one closed cytosolic and periplasmic portal.

8 rposes, which are also available through the portal.

9 re available in BioCyc.org and other genomic portals.

10 top of one another at one of the macrocycle portals.

11 ds during purification, but only if they had portals.

12 e cytosolic side that is fenestrated by side portals.

13 ation Bias Recovery In Coding-regions Cancer Portal, a comprehensive catalogue of gene selection in c

14 low-income adults with uncontrolled asthma, portal access and CHWs produced small incremental benefi

15 OCTAD is available as a web portal and a standalone R package to allow experimental

16 roposed, a base-catalyst mediated by the CB7 portal and an inhibitory role attributed to the lower in

17 mode of protein-protein interactions between portal and capsid, across a symmetry-mismatched interfac

18 an asymmetrically attached DNA-translocating portal and capsid-associated tegument complexes from cry

19 he associated functional differences between portal and central hepatocytes is missing thus far.

20 caling of the maximal activities to generate portal and central instantiations of a comprehensive kin

21 The SHAPE gradient between the portal and hepatic veins was in good overall agreement w

22 determined the in situ structure of the KSHV portal and its interactions with surrounding capsid prot

23 f betacyanins in the gastric content, blood (portal and main veins) and urine of rats after an intrag

24 ological insulin balance between the hepatic portal and peripheral circulations and thereby avoid the

25 ulminate in clinical conditions ranging from portal and pulmonary hypertension to pulmonary, cardiac

26 phere also occurred directly from the tunnel portal and should be monitored in future tunnel gas samp

27 he intestinal barrier causing an increase in portal and systemic gut-derived antigens, which challeng

28 of deviation from icosahedral symmetry, KSHV portal and tegument structures have largely been obscure

29 s attributed to stabilization of the quinone portal and the hinge region of the iron-sulfur protein.

30 d the structure of YbiO, which showed larger portals and a wider pore with no GGxGG motif.

31 These results suggest that portals and capsids influence each other's conformation

32 ed bound to membrane-like fragments by their portals and could be disaggregated by detergents, suppor

33 In short, the ATPase, portal, and dsDNA work synergistically to promote genome

34 Portals are essential and serve as the pore for DNA tran

35 In YnaI, these portals are obstructed by aromatic side chains but are s

36 lly linked to create bidirectional transport portals at the ER-Golgi interface.

37 c IRI, and suggest a diagnostic screening of portal blood for reactivity to these PRRs might prove us

38 Portal blood immediately following allograft reperfusion

39 We screened portal blood samples obtained from 67 human liver transp

40 atosis, ballooning, Mallory-Denk bodies, and portal, but not lobular, inflammation.

41 ted at a unique central nervous system entry portal called the velum interpositum, where they express

42 r associated toxins to the liver through the portal circulation.

43 Following portal co-expression, portals were incorporated into abo

44 alth workers (CHWs) plus training in patient portals compared with usual care and portal training onl

45 te of expansion induced by the presence of a portal complex in cleaved HK97 proheads.

46 f asymmetry, a 12-fold-symmetric dodecameric portal complex inserted into a 5-fold-symmetric capsid v

47 Early vascular (arterial and portal) complications can represent a threat for the gra

48 The portal covers the entire human coding genome (~18,000 pr

49 Portal decompression procedures prior to surgery (n = 10

50 ction in GLP-1r density, leads to functional portal desensitization with a consequent suppression of

51 eads without portal or cleaved proheads with portal did not bind.

52 The pUL6 portal dodecamer is anchored at one vertex of the capsid

53 antified by RNA-seq and a user-friendly data portal, enabling a broad range of biomedical investigati

54 using data on the genotype-tissue expression portal expression quantitative trait loci database and a

55 cts liver function; however, scar-generating portal fibroblasts also provide important instructive si

56 is surrounded by stromal cells often called portal fibroblasts.

57 ges in the liver included hepatic steatosis, portal fibrosis, lymphocytic infiltrates and ductular pr

58 elected combined serum alpha-fetoprotein and portal flow (F (p) ) skewness (area under the curve [AUC

59 While portal flow (PF) plays an important role in determining

60 in hepatic venous portal gradient (HVPG) and portal flow of -28.3% and -29.1%, respectively.

61 cal vein was successfully achieved with good portal flows and macroscopically homogeneous perfusion.

62 l structures across bacteriophages share the portal fold and maintain a conserved function.

63 on was collected from the online ForeseeHome portal for all eyes prescribed the device.

64 onnectivity and develop a user-friendly data portal for community use.

65 We have established a modern web portal for efficient finding, exploration and export of

66 ngiotensin-converting enzyme 2 serves as the portal for infection, the role of angiotensin-converting

67 GeoNet was used on data in the Water Quality Portal for the Pennsylvania Marcellus region.

68 rted conformational changes open the lateral portals for ion conduction, rendering ion conduction thr

69 ify Lamp1(+) late endosomes and lysosomes as portals for passing proteins into the cytosol and sugges

70 Central for portal function is the bridging glycoprotein MFG-E8.

71 This reflected a reduction in portal GLP-1r binding potential, particularly between th

72 GLP-1-dependent portal glucose signaling was identified, in vivo, using

73 nsequent suppression of vagal sensitivity to portal glucose.

74 ith a significant decrease in hepatic venous portal gradient (HVPG) and portal flow of -28.3% and -29

75 nsive investigation including hepatic venous portal gradient measurement and liver biopsy revealed no

76 A dedicated portal has been developed to provide quick and focused a

77 In LT, portal hyperperfusion can severely impair graft function

78 82% were male, 78% had cirrhosis, most with portal hypertension (61%, n=46/76), and 18% had prior-LT

79 sitive) with baseline clinically significant portal hypertension (CSPH; HVPG >=10 mmHg) and SVR after

80 Patients with NASH, cirrhosis, and portal hypertension (hepatic venous pressure gradient [H

81 Portal hypertension (PH) is the main driver of cirrhosis

82 interferon (IFN)-free therapies ameliorates portal hypertension (PH); however, it remains unclear wh

83 Portal hypertension and esophageal varices needing treat

84 of hepatic fibrosis which ultimately causes portal hypertension and gastroesophageal varices.

85 ic hepatitis (AH) with advanced fibrosis and portal hypertension and in experimental mouse fibrosis.

86 arterial (PA) hypertension in patients with portal hypertension and is associated with significant m

87 ges due to performed procedures, because the portal hypertension and it's further complications had n

88 With improved understanding of portal hypertension and the dynamic physiology of collat

89 eNOS activity and to a dramatic increase in portal hypertension compared to BDL in wild-type mice.

90 interventional treatments for patients with portal hypertension complications as well as to highligh

91 les) with patent umbilical vein and signs of portal hypertension due to liver cirrhosis.

92 ssociated with intrahepatic angiogenesis and portal hypertension during late-stage fibrosis, and hete

93 SA class, anesthesia type, inpatient status, portal hypertension history, and variable complication r

94 LCN2 contributes to liver fibrosis and portal hypertension in AH and could represent a new ther

95 ading to extracellular matrix production and portal hypertension in liver cirrhosis.

96 ative SHAPE to HVPG measurements to diagnose portal hypertension in participants undergoing a transju

97 sed and correlated with disease severity and portal hypertension in patients with AH.

98 f galectin 3 that reduces liver fibrosis and portal hypertension in rats and was safe and well tolera

99 utant previously identified in a family with portal hypertension indicated basal constitutive channel

100 Advanced fibrosis and portal hypertension influence short-term mortality.

101 Portal hypertension is a clinical syndrome characterized

102 The most frequent cause of portal hypertension is cirrhosis.

103 rrent standard for assessing the severity of portal hypertension is the invasive acquisition of hepat

104 In patients with cirrhosis, portal hypertension is the main driver of cirrhosis prog

105 may underestimate complications arising from portal hypertension or infection.

106 The portal hypertension probably could be a result of incomp

107 classifications; explore and illustrate new 'portal hypertension theories' of gastric variceal diseas

108 leeding have changed after the emergence of 'portal hypertension theories' of proximity, throughput,

109 dy of 162 patients with NASH, cirrhosis, and portal hypertension, 1 year of biweekly infusion of bela

110 Sinusoidal portal hypertension, a disorder characterized by liver s

111 oalbuminemia, cardiocirculatory dysfunction, portal hypertension, and systemic inflammation in patien

112 rican Society of Anesthesiologists (ASA) >2, portal hypertension, intraoperative blood transfusions,

113 urs in the context of advanced cirrhosis and portal hypertension, is associated with particularly hig

114 n damage (eg, cytopenias, liver dysfunction, portal hypertension, malabsorption, and weight loss).

115 experienced participants with cirrhosis and portal hypertension, prior liver transplantation (LT) or

116 After the operation portal hypertension, with splenomegaly and symptoms of t

117 Sixteen (33%) patients had one or more portal hypertension-related complication within 3 months

118 h as swallowing difficulty, hepatomegaly and portal hypertension.

119 chnique for detecting clinically significant portal hypertension.

120 econdary liver changes such as cirrhosis and portal hypertension.

121 other patients (1%) developed non-cirrhotic portal hypertension.

122 lications for the pathogenesis of sinusoidal portal hypertension.

123 ted with advanced liver cirrhosis and severe portal hypertension.

124 l contributor, with no significant effect of portal hypertension.

125 y revealed no evidence of hepatic disease or portal hypertension.

126 (TIPS) creation is an accepted treatment of portal hypertension.

127 -MD-02 in patients with NASH, cirrhosis, and portal hypertension.

128 me results in a dramatic displacement of the portal.IMPORTANCE Herpes simplex virus 1 (HSV-1) is the

129 ets, store files and link to the ALA spatial portal, improve graphics and provide the novel ability t

130 lack of workflows to support patient use of portals in routine practice.

131 ive assay for identification and analysis of portal incorporation mutants.

132 gestion that P22 uses a unique mechanism for portal incorporation.

133 use of patient portals, usability testing of portal interfaces, and documentation of patient and clin

134 The Genomic Data Commons (GDC) Data Portal is a platform that contains different genomic stu

135 The portal is available at fabric-cancer.huji.ac.il.

136 Gene selection in the portal is quantified by combining genomics data with ric

137 How only one portal is selectively incorporated at a unique vertex is

138 The LINCS Data Portal (LDP) has been the primary access point for the c

139 ded lung (33 patients), peritoneum (32), and portal lymph nodes (14).

140 e antennal gland," are major candidate entry portals [M.

141 method is therefore applicable to radiation portal monitors deployed in the field and could improve

142 anic scintillators are used within radiation portal monitors to detect gamma rays emitted from convey

143 Remarkably, the local structure of portal morphs to compensate for symmetry-mismatch, formi

144 as a "closed vestibule," with their lateral portals obstructed by loops and their cytosolic ends for

145 of the phenyl moiety in CB[7] by capping the portal of CB[7].

146 similarly, FcRn recycles albumin and is the portal of entry for enteric cytopathic human orphan (ech

147 y hostile environment is known to serve as a portal of entry for herpesviruses.

148 The intestinal tract represents a portal of entry for many infectious agents; however, to

149 As the main portal of entry for shrimp-related pathogens remain uncl

150 The activation of CD81 [the portal of entry of hepatitis C virus (HCV)] by agonistic

151 the female genital tract, which is often the portal of HIV-1 entry and which remains a site of infect

152 iance of Genome Resources website, the joint portal of NIH-funded model organism databases.

153 t Protein Data Bank (PDB)-101, the education portal of the RCSB PDB.

154 These mucosal gateways are not only portals of entry for potential pathogens but also homes

155 memory T cells (TRM cells) are poised at the portals of infection and provide long-term protective im

156 detergent, while uncleaved proheads without portal or cleaved proheads with portal did not bind.

157 The question remains whether the lateral portals or cytosolic constriction conduct ions upon chan

158 pick up, CD via mail, e-mail, online patient portal, or other online access), departments from which

159 Machine perfusion with portal perfusion via the umbilical vein is feasible.

160 NE(-/-) and Pad4(-/-) mice had lower portal pressure and livers had less fibrin compared with

161 actor (vWF) antigen (vWF-Ag) correlates with portal pressure and seems capable of predicting complica

162 rogate endpoint for interventions that lower portal pressure by decreasing intrahepatic resistance.

163 nto sinusoidal lumen of liver might increase portal pressure by promoting sinusoid microthrombi.

164 syndrome characterized by an increase in the portal pressure gradient, defined as the gradient betwee

165 n, plasma renin, cardiocirculatory function, portal pressure, and plasma levels of cytokines, collect

166 the major capsid protein (mcp) together with portal, protease, and decoration proteins.

167 angstrom resolution crystal structure of the portal protein and DNA packaging assays, these reconstru

168 Our results highlight a key function of portal protein as an assembly initiator, a feature that

169 Twelve subunits of the portal protein define a tunnel, through which DNA is tra

170 hage P22 assembly in vivo indicated that the portal protein did not function as a nucleator for proca

171 It is unknown how the portal protein functions as a gatekeeper, preventing DNA

172 also catalyzes oligomerization of monomeric portal protein into dodecameric rings, possibly forming

173 The portal protein is a key component of many double-strande

174 ings, possibly forming a scaffolding protein-portal protein nucleation complex that results in one po

175 A cryo-EM structure of the portal protein of thermostable virus P23-45, determined

176 id expansion affects the conformation of the portal protein, while still allowing DNA to be packaged.

177 Due to their dynamic role, portal proteins are surprisingly plastic, and their conf

178 The portal proteins of tailed bacteriophage and Herpesvirus

179 icance of our research is in identifying the portal proteins pUL6 and pUL17 as key viral factors for

180 ent (CVSC) proteins pUL17 and pUL25; and the portal proteins pUL6 and pUL32.

181 this dataset and an accompanying public data portal provide a resource for the acceleration of cancer

182 A new cancer portal quantifies and presents gene selection in tumor o

183 ion experiments revealed a role for both the portal region of P2 and its opposite face in membrane in

184 gG4 enhanced plasma cell infiltration in the portal region of the liver, and satisfaction of the crit

185 gG4 positive plasma cell infiltration in the portal region, without evidence of bile duct injury.

186 Since the initial portal release in 2013, the ENCODE DCC has updated the p

187 viruses.IMPORTANCE The existence of a single portal ring is essential to the formation of infectious

188 otein nucleation complex that results in one portal ring per P22 procapsid.

189 sults document a discrete change in the HK97 portal's hydrophobicity induced by cleavage of the proca

190 We provide a web portal (seeker.pythonanywhere.com) and a user-friendly P

191 The glucose portal sensor informs the brain of changes in glucose in

192 in situ tridimensional representation of the portal sensor with specific reference to the receptor de

193 consequences of GLP-1 resistance on glucose portal signaling.

194 Despite having low sequence similarity, portal structures across bacteriophages share the portal

195 al blood flow as in a so-called insuloacinar portal system.

196 rominently assumed that social media and web portals that aggregate news restrict the diversity of co

197 ent engagement with EHR data through patient portals, These studies mostly involved outpatient settin

198 rtnership type 2 diabetes mellitus Knowledge Portal to evaluate whether candidate genes prioritized b

199 We developed CoDEx, an online portal to facilitate data access and browsing.

200 ease in 2013, the ENCODE DCC has updated the portal to make ENCODE data more findable, accessible, in

201 Data Bank (RCSB PDB) provides an integrated portal to the PDB archive that streamlines access for mi

202 ition of the methyl groups that encircle the portal to their non-polar pockets.

203 ent of health care systems now offer patient portals to access electronic health records (EHRs) in th

204 The model simulations revealed significant portal-to-central differences in almost all metabolic pa

205 re found only surrounding the main duct of a portal tract but not the epithelial cells of the ductula

206 The portal tract contains the bile duct, which is surrounded

207 Liver demonstrated normal portal tract, with no parenchymal necrosis, inflammation

208 The main cell types in the portal tracts and lobules were CD3+ and CD68+ cells.

209 In the presence of inflammation, portal tracts were enriched in CD3+, CD20+ but displayed

210 itment of Th17 cells and more monocytes into portal tracts.

211 patient portals compared with usual care and portal training only.

212 an exclusive re-localization of PAFR to the portal triad.

213 In liver lobules, blood flows from portal triads that are situated in periportal lobular re

214 These tools are ICGC Data Portal, UCSC Xena, Chromothripsis Explorer, Expression A

215 endering ion conduction through the vertical portal unlikely.

216 es: interventions to increase use of patient portals, usability testing of portal interfaces, and doc

217 6 months by CHWs to facilitate competency in portal use and promote care coordination.

218 alth or digital literacy faced challenges to portal use.

219 nt training were associated with the highest portal use.

220 ntation of patient and clinician barriers to portal use.

221 ey role of clinicians and staff in promoting portal use.

222 ion (CTP) algorithms in Philips IntelliSpace Portal (v9, ISP) and to investigate optimal thresholds f

223 etermined that in insulin-resistant animals, portal vagal afferents failed to inhibit their spiking a

224 The liver connects the intestinal portal vasculature with the general circulation, using a

225 No vascular grafts (VG) were required for portal vein (PV) anastomosis.

226 human liver transplant recipients both pre- [portal vein (PV) sample] and post-(liver flush; LF) repe

227 g infusion, SHAPE data were collected from a portal vein and a hepatic vein, and the difference was c

228 Levels of amino acids in the hepatic portal vein and caudal vein were measured at intervals a

229 the dendritic nature of the hepatic artery, portal vein and hepatic vein can be predicted, together

230 systemic collateral channels and diameter of portal vein and positive correlation between diameter of

231 radient, defined as the gradient between the portal vein at the site downstream of the site of obstru

232 val index, tooth mobility; liver status, and portal vein caliber by ultrasound examination; bone retr

233 OR:1.3; 95%CI:1.2-1.5; p < 0.001), increased portal vein diameter (OR:1.2; 95%CI: 1.07-1.4; p = 0.003

234 l shunts and their relationship with age and portal vein diameter.

235 Abdominal ultrasonography and portal vein doppler ultrasonography were performed in19

236 epatectomy (0%, 3%, 4%, P < 0.001), need for portal vein embolization (5%, 9%, 9%, P = 0.001), preope

237 m of this retrospective study was to compare portal vein embolization (PVE) and radiologica simultane

238 After portal vein embolization (PVE), 15% of patients remain i

239 comorbidities, hepatic function, ASA class, portal vein embolization rate)(p > 0.05).

240 patic vascular occlusion (rate or duration), portal vein embolization, drain use, etc.)(p > 0.05).

241 h conventional 2-stage hepatectomy including portal vein embolization.

242 is effective reliably even after failure of portal vein embolization.

243 s in the ratio of insulin to glucagon in the portal vein have a major role in the dysregulation of he

244 Clinical status, portal vein hemodynamics, morphology of the liver, de no

245 sential amino acids over time in the hepatic portal vein in contrast to that of the non-selected stra

246 Associating liver partition and portal vein ligation (PVL plus transection=ALPPS) or the

247 Portal vein ligation (PVL) induces liver growth prior to

248 ing partial hepatectomy (PH), intraoperative portal vein ligation (PVL), and associated liver partiti

249 on (PVL), and associated liver partition and portal vein ligation for staged hepatectomy (ALPPS) show

250 radiological associating liver partition and portal vein ligation for staged hepatectomy." RASPE indu

251 nt a left hepatectomy with ligation of right portal vein maintaining the right hepatic artery patent.

252 n patients (58%) had borderline or increased portal vein minimum and maximum flow velocities.

253 ons, especially limited tissue volume due to portal vein pressure.

254 ts, and direct-acting anticoagulants improve portal vein repermeation vs observation alone.

255 Portal vein thrombosis (PVT) occurs frequently in hepato

256 ion (Budd-Chiari Syndrome) and in those with portal vein thrombosis (second section); and we briefly

257 ther evaluations revealed a mild ascites and portal vein thrombosis although the patient received pro

258 Left sided abscess and portal vein thrombosis are rare and hence reported.

259 We speculated that the underlying cause of portal vein thrombosis in our case was coronaviruses.

260 Segmental left portal vein thrombosis occurred in 1 patient and intralu

261 e lab data regarding the secondary causes of portal vein thrombosis were normal.

262 a higher change of complications related to portal vein thrombosis.

263 e the relationship between folate status and portal vein thrombosis.

264 source of infection and presenting with left portal vein thrombosis.

265 from the gastrointestinal tract through the portal vein to the liver.

266 ents with hepatocellular carcinoma (HCC) and portal vein tumor thrombosis (PVTT) is 2-6 months; conve

267 Portal vein tumour thrombosis is common among patients w

268 iver communicates with the intestine via the portal vein, biliary system, and mediators in the circul

269 Twenty-four of these showed bactDNA in the portal vein, matching peripheral blood-identified bactDN

270 ndard) islets from BALB/c (H-2) mice via the portal vein.

271 ed bile acids are delivered to the liver via portal vein.

272 er to host epithelial tissue and the hepatic portal vein.

273 y excretion, and the signal intensity in the portal vein.

274 ameter of paraumbilical vein and diameter of portal vein.

275 n when islet cells are transplanted into the portal vein.

276 abscess cavity along with thrombosis of left portal vein.

277 a double perfusion of the hepatic artery and portal vein.

278 in the recipient without interruption of the portal venous circulation.

279 ortal venous wedge pressure, and reversal of portal venous flow on Doppler ultrasonography should not

280 Bowel findings included pneumatosis or portal venous gas, seen on 20% of CT images obtained in

281 ated cirrhosis and severe PH; an effect upon portal venous inflow is likely, and concomitant decrease

282 e beta-blockers (NSBBs) that act by reducing portal venous inflow.

283 We aimed to assess the feasibility of portal venous machine perfusion via the umbilical vein.

284 nd iodine material density (MD) images, plus portal venous phase (PVP) conventional CT images.

285 ntrast phase (PCP), arterial phase (AP), and portal venous phase (PVP) scans.

286 d CT images obtained during the arterial and portal venous phases, independently and in consensus, wi

287 In all livers, access to the portal venous system via the umbilical vein was successf

288 y recommendations include: (1) liver biopsy, portal venous wedge pressure, and reversal of portal ven

289 in situ structure of the symmetry-mismatched portal vertex from bacteriophage T4.

290 The motor assembles transiently at the portal vertex of an empty precursor capsid (or procapsid

291 and structural studies focused on the unique portal vertex of wild-type HSV and packaging mutants pro

292 erminase complex and pUL25 with pUL17 at the portal vertex, and (vi) packaging of the viral genome re

293 ncer genes, demonstrating the utility of the portal via its simple visual interface, which allows use

294 Following portal co-expression, portals were incorporated into about half of the prohead

295 psid proteins assemble efficiently without a portal when expressed from plasmids.

296 e utilized SATurn to create a bioinformatics portal which routinely supports a diverse group of scien

297 phage (SMs) that provide a cell-cell contact portal, which facilitates the uptake of HIV-1 viral-like

298 The data portal, which facilitates web-based exploration of the I

299 gher rates of patient engagement through EHR portals will require paying more attention to the needs

300 We showcase the portal with known and overlooked cancer genes, demonstra

301 rough multiple access modes, including a web portal with specialized visualization modules.