ライフサイエンスコーパス: pose

1 Identical ligand pairs show the same binding poses.

2 possible poses, and then scores the refined poses.

3 onds in oligosaccharides and glycoconjugates pose a bottleneck in enabling the remarkable promise of

4 uctuations, together with measurement noise, pose a challenge for the dynamical analysis of these Bro

5 ty like Autism Spectrum Disorder (ASD) often pose a challenge for traditional genome-wide association

6 eneous sub-populations, varying sample sizes pose a challenge in the estimation and inference, as net

7 ry structures and telomeric protein binding, pose a challenge to BIR and increase the vulnerability o

8 Conjoined twins are rare and pose a challenge to radiologists and surgeons.

9 We conclude that adversarial images still pose a challenge to theorists using DCNNs as models of h

10 Decompensated patients often pose a complex challenge which typically requires a mult

11 Flaviviruses pose a constant threat to human health.

12 Multi-resistant organisms (MROs) pose a critical threat to public health.

13 e potential to form secondary DNA structures pose a frequent and significant impediment to DNA replic

14 Invasive organisms pose a global threat and are exceptionally difficult to

15 is one of the most destructive diseases that pose a great threat to wheat production.

16 crowded compared with previous ones, it will pose a greater challenge to existing image processing me

17 nd that exposure to chemical dispersants may pose a greater threat than oil itself.

18 nces (PFASs) that can be very persistent and pose a health risk to biota and humans.

19 ying mosquito species (disease vectors) that pose a health risk to humans and livestock.

20 sumption of poppy seed-containing food could pose a health risk.

21 ssues retain gadolinium, which might further pose a health threat due to toxic effects of free gadoli

22 s respect, the size and shape of the nucleus pose a major limitation.

23 ironmental contaminants and are suspected to pose a major public health concern.

24 Ebola virus (EBOV) epidemics pose a major public health risk.

25 Invasive species pose a major threat to global biodiversity.

26 These can pose a pandemic threat through reassortment and emergenc

27 Seasonally elevated Al concentrations may pose a particular threat to freshwater organisms.

28 Although iron deficiency continues to pose a problem for pregnant women and fetal development,

29 d replication where barriers are expected to pose a problem to efficient DNA bubble migration.

30 uses (CIVs) prevalent in dogs are thought to pose a public health threat arising from intimate contac

31 elements during a weight loss program could pose a risk to human health.

32 Infections caused by Staphylococcus aureus pose a serious and sometimes fatal health issue.

33 Anthraquinone dyes pose a serious environmental problem as their reinforced

34 d-band white-light emission properties, they pose a serious long-term environmental and health risk a

35 ted daily intake calculation, samples do not pose a serious risk to public health.

36 Mycotoxins, such as aflatoxin B(1) (AFB(1)), pose a serious threat as biological weapons due to their

37 eath globally, and drug-resistant TB strains pose a serious threat to controlling the global TB epide

38 (MARV) viruses, are emerging pathogens that pose a serious threat to public health.

39 o their efficient transmission, arenaviruses pose a severe risk for outbreaks and might be exploited

40 fts in community structure and may therefore pose a severe threat to soil microbial communities, espe

41 HLA antibodies pose a significant barrier to transplantation and curren

42 ntext-dependent consequences of species loss pose a significant challenge, the predictability of cumu

43 s and management of tubercular uveitis (TBU) pose a significant challenge.

44 ithromycin, cefotaxime, and trimethoprim all pose a significant risk for selection of AMR in the envi

45 Plant-parasitic nematodes pose a significant threat to agriculture causing annual

46 ons of the less abundant chlorocarbons could pose a significant threat to the recovery of the ozone l

47 Filoviruses such as Ebola virus continue to pose a substantial health risk to humans.

48 existing knowledge about these networks, we pose a testable framework for understanding how hyper- v

49 in drought frequency due to climate change, pose a threat to plant growth and productivity which cou

50 d during the entire lifespan of plastics and pose a threat to the environment and human health.

51 shed with limited distribution) species that pose a threat to the EU, as identified by horizon scanni

52 Synthesis of NTs with Magneli phases have posed a challenge due to the degradation and loss of mor

53 ough the origins of such strange metals have posed a long-standing mystery.

54 the hypothesis that cardiomyocyte polyploidy poses a barrier for cardiomyocyte proliferation and subs

55 However, the time required to generate them poses a bottleneck.

56 This poses a challenge for accurately estimating burden of di

57 example of a magnetic molecular system that poses a challenge for computational quantum chemistry.

58 COVID-19 poses a challenge for heart transplantation, affecting d

59 illation limits its therapeutic efficacy and poses a challenge for potential patient compliance.

60 Metabolic heterogeneity among human tumors poses a challenge to developing therapies that exploit m

61 Cancer metastasis poses a challenging problem both clinically and scientif

62 uction, but degradation in biological fluids poses a considerable roadblock to biomedical application

63 novel influenza viruses through reassortment poses a continuing risk to public health.

64 schemic stroke (IS) from stroke mimics (SMs) poses a diagnostic challenge.

65 Clinical rejection poses a far greater risk for future CAV than rejection o

66 ltifactorial pathogenic mechanisms, COVID-19 poses a global threat to the entire nervous system.

67 nce of dry eye disease is high worldwide and poses a great burden on patients' daily lives.

68 mely low concentration of pathogens in blood poses a great challenge for rapid and ultrasensitive det

69 coronavirus disease 2019 (COVID-19) pandemic poses a great challenge to the public health system.

70 ur society, but their limited lifetime still poses a great challenge.

71 that temperature-mediated trophic asynchrony poses a growing risk to consumers.

72 s limits their clinical interpretability and poses a key barrier to the broad utility of carrier scre

73 tament to their exceptional adaptability and poses a major challenge for developing effective strateg

74 The increasing prevalence of type 2 diabetes poses a major challenge to societies worldwide.

75 or activated oncogenes in pediatric cancers poses a major challenge to the evolving paradigm of pers

76 ng benefits and risks is a complex task that poses a major challenge, both to the approval of new med

77 therapeutically beneficial properties still poses a major challenge.

78 an important role in aquatic ecosystems and poses a major problem for drinking water production.

79 xtreme-but-rare events become common), which poses a major risk to the safety and sustainability of c

80 ssociated with hematopoietic differentiation poses a major threat to genome stability and cell viabil

81 Ocean acidification (OA) poses a major threat to marine ecosystems and shellfish

82 ication.IMPORTANCE African swine fever (ASF) poses a major threat to pig populations and food securit

83 For migratory herbivores, climate change poses a new and growing threat by altering resource phen

84 This capacity however poses a new challenge for analysis of multiple data sets

85 The re-emergence of scarlet fever poses a new global public health threat.

86 evolution of antimicrobial resistance (AMR) poses a persistent threat to global public health.

87 This poses a problem for the macrophage and raises the fundam

88 The scope of human learning and development poses a radical challenge for cognitive science.

89 ted to both clinical and procedural factors, poses a recurring dilemma in clinical practice.

90 the kidney, is a growing concern because it poses a risk of renal scarring and irreversible loss of

91 This poses a risk to public health as waste is a vector for S

92 of antibiotic resistance in bacteria, which poses a serious risk to human and livestock health when

93 This poses a serious roadblock for clinical translation of th

94 This poses a severe limitation to our understanding on the ea

95 s a highly toxic heavy-metal pollutant which poses a significant health risk to humans and other ecos

96 nderstanding of the disease, B. pseudomallei poses a significant health risk, especially in regions o

97 rcinoma, and treatment of biliary strictures poses a similarly significant clinical challenge.

98 This scaling relation poses a stringent test for the validity of the TDT.

99 cules from the diet is poorly understood and poses a substantial obstacle to harnessing their potenti

100 the aggregated effect of energy transitions poses a substantial threat to global biodiversity.

101 ature of oncogenic Myc transcription factors poses a therapeutic challenge in neuroblastoma, a pediat

102 Retrotransposon proliferation poses a threat to germline integrity.

103 oci instead of protein-coding loci, however, poses a unique challenge in discerning which among the m

104 ve-ground biomass, but this integral feature poses a weight-induced challenge to trunk stability.

105 ization to different tissue and tumor types, posing a barrier to adoption.

106 sputum, is highly viscous and heterogeneous, posing a challenge for sample processing.

107 factors related to its genetic abnormality, posing a challenge for the management of OSA.

108 ndergo nuclear degradation for transparency, posing a challenge: how is their cell morphology, also c

109 EC) cause acute secretory diarrhoea in pigs, posing a great economic loss to the swine industry.

110 t is recognized as highly immunosuppressive, posing a major hurdle for inducing immune-mediated destr

111 e caused by non-polio enterovirus infection, posing a major public health challenge.

112 widely used in microfluidic prototyping, but posing a number of challenges to experimentalists, inclu

113 n they maintain a diverse natural reservoir, posing a risk to humans through the occasional emergence

114 th human coronaviruses are not yet approved, posing a serious challenge to current global efforts aim

115 mechanically flexible and stretchable, thus posing a significant challenge.

116 isoning and causes avian necrotic enteritis, posing a significant problem to both the poultry industr

117 between redox-sensitive elements, which may pose additional risks to groundwater-reliant individuals

118 lly present in samples at low concentrations pose an analytical challenge.

119 DNA gaps greater than 1 nucleotide (nt) pose an architectural and logistical problem for the two

120 l shape and the retina of the biological eye pose an enormous fabrication challenge for biomimetic de

121 rces settle in the sediments, where they may pose an environmental threat to benthic organisms.

122 DNA double-strand breaks (DSBs) pose an everyday threat to the conservation of genetic i

123 emics, such as the one caused by SARS-CoV-2, pose an imminent threat to humanity.

124 We hypothesized that the CHs pose an increased predation risk to young calves for cat

125 ed in the literature, and its interpretation poses an empirical and conceptual challenge.

126 near the epithelial surface of the intestine poses an enormous challenge to the host because it must

127 1 blockade results in AP prolongation, which poses an increased risk of sudden cardiac death.

128 ia in East Tennessee is associated with IDU, posing an additional burden from the opioid crisis.

129 Organization has included three bunyaviruses posing an increasing threat to human health on the Bluep

130 inhaled droplets and aerosol particles, thus posing an inhalation threat even at considerable distanc

131 ated with increasing morbidity and mortality posing an urgent threat to public health.

132 sites and complex O-GalNAc glycan structures pose analytical challenges.

133 The docking results did not match the known pose and affinity of Olmesartan.

134 ocking, presenting the user with top-scoring poses and their confidence scores.

135 Structural insights into setron-binding poses and their inhibitory mechanisms are just beginning

136 refinement to produce a variety of possible poses, and then scores the refined poses.

137 tomato at recommended dose, does not seem to pose any dietary risk to the consumers.

138 resent, at what concentrations, and if those posed any potential long-term health risks.

139 ants agreed or strongly agreed with IDD when posed as a general question and in relation to the case

140 genome rearrangements, this problem is often posed as minimization of the number of genome rearrangem

141 ectious disease 2019 (COVID-19) pandemic has posed at risk the kidney transplant (KT) population.

142 vioral statistics describing the locomotion, pose, biting, and feeding dynamics of Aedes aegypti, Aed

143 ir existence: namely, the threat to survival posed by antagonizing bacteria.

144 meters used to assess the public health risk posed by arboviruses(3).

145 gically, we highlight critical opportunities posed by assessing spatial variation in host tolerance,

146 an efficient way for assessment of the risk posed by avian IAVs, such as in evaluating their potenti

147 cally, compounding the ecophysiological risk posed by climate change, as the combined effects are mor

148 for their ability to adapt to the challenges posed by climate change, which hampers the implementatio

149 s that, to be ethically justified, the risks posed by current state-of-the-art options must outweigh

150 of the challenge to animal and human health posed by excessive use of antimicrobials in aquaculture.

151 Given the risk of added vision loss posed by exudative vitreoretinopathy in patients with RP

152 We address two challenges posed by growth in data size and complexity.

153 prioritize management effectively, the risks posed by IAS need to be assessed, but so too does the fe

154 ing disease, could greatly reduce the threat posed by its etiologic agent, SARS-CoV-2.

155 To overcome the challenge posed by low frequency of the AA genotype (appr.

156 rch, and the security and transparency risks posed by machine learning algorithms.

157 magnitude of bias in predicting disease risk posed by measuring vaccination rates at coarse spatial s

158 ot currently possible to determine the risks posed by microplastics retained within the world's river

159 important in assessing the potential threats posed by microplastics to polar organisms.

160 mental GVs, reporting and assessing the risk posed by multiple stressors.

161 elated to the emergence and potential threat posed by NOVC strains under a rapidly changing environme

162 The response of bacteria to the threat posed by phages depends on their local environment.

163 The threat posed by plastic pollution to marine ecosystems and huma

164 en foundational, yet unresolved, ELSI issues posed by portable neuroimaging: (1) informed consent; (2

165 atic and host environments, including stress posed by reactive oxygen species (ROS).

166 force to overcome barriers to translocation posed by structured substrate proteins is unknown.

167 ed cases, respectively-highlighting the risk posed by substantial covert infections when changing con

168 data, systems biology addresses the problems posed by the complex organization of biological processe

169 nse strategies to combat the constant threat posed by the diverse genetic parasites that endanger the

170 To investigate the constraints posed by the limited access to biodiversity data, we emp

171 r efforts addressing the enormous challenges posed by the ongoing extinction and climate emergencies.

172 can be exploited to address the limitations posed by the spatiotemporal sparseness of the observatio

173 Experimental challenges posed by these properties have greatly impeded our under

174 st rapidly adapt to the tremendous challenge posed by this and potential future pandemics.

175 ponse by female elk to the risk of predation posed by wolves in northern Yellowstone.

176 tal duplications with high sequence identity pose challenges for long-read mapping.

177 privation, and lactic acidosis, all of which pose challenges for protein processing in the ER.

178 susceptibility testing (AST) of cefiderocol poses challenges because of its unique mechanism of acti

179 The diverse composition of mammalian tissues poses challenges for understanding the cell-cell interac

180 Complex behavior poses challenges in extracting models from experiment.

181 ied under other dominant chemical signatures posing challenges to an effective classification based o

182 on in intermolecular radical reactions still poses challenging issues.

183 unted for by environmental heterogeneity and poses challenging questions for understanding the specia

184 ght persist at a subclinical level and might pose clinical risks in the post-LT period.

185 Both equifinality and multifinality pose considerable challenges to uncovering underlying me

186 ar, with its costly, multidisciplinary care, poses considerable financial and ethical challenges for

187 late among wild birds and poultry worldwide, posing constant pandemic threats to humans.

188 sest ideal Cn symmetric complex from docking poses containing a homo-dimer without prior knowledge of

189 actor paradigm in bioinorganic chemistry and pose countless outstanding questions.

190 etermine the outcome of drug-induced ICD and pose COX-2/prostaglandin E(2) blockade as a strategy to

191 mium are known cardiovascular toxicants that pose disproportionate risk to rural communities where en

192 s associated with poor survival outcomes and poses distinct clinical challenges.

193 of mitochondria and low sample availability pose distinctive challenges for in situ functional studi

194 rrence of contaminants in drinking water may pose enhanced risks to health beyond the effects of sing

195 Recent advances in pose estimation with deep learning allows researchers to

196 tic images of a small number of artificially posed expressions taken under tightly controlled experim

197 applied with SIP and returns the near-native poses for 76% of the test set within the top-10, outperf

198 rome coronavirus 2 (SARS-CoV-2) pandemic has posed formidable challenges for clinical laboratories se

199 Although this complexity poses formidable challenges to understanding the underly

200 The complexity of this workflow poses formidable technical challenges, thus limiting wid

201 tally alter the architecture of human sleep, posing fundamental questions about the link between slee

202 hundreds of thousands, yet low sample sizes, poses great challenge for machine learning-based predict

203 fections in immunocompromised patients still poses great challenges.

204 HA and alpha-2,6 receptor binding in tandem pose greater pandemic risk.

205 lead to death of the user and simultaneously pose hazards for first responders.

206 respectively, in drinking-water supplies may pose human-health concerns.

207 ed and high-dimensional, we formulate a well-posed hypothesis from a Bayesian point of view and sugge

208 labile character of their metal-ligand bonds pose important challenges.

209 coronavirus disease 2019 (COVID-19) pandemic poses important challenges to the care of patients with

210 in genetic analyses and in breeding schemes poses important statistical and computational challenges

211 This PAX-binding pose in closed BK channels is supported by additional fu

212 less motion capture system for estimating 3D pose in freely moving macaques in large unconstrained en

213 served that the most energetically favorable pose includes a TPN orientation that coordinates to the

214 s and questions that the new treatments have posed, including the effects of treatment at different a

215 onavirus disease 2019 (COVID-19) pandemic is posing insurmountable challenges to healthcare systems g

216 This poses limitations on our understanding of PM health effe

217 d with feedforward processing than gamma and pose limits on the proposed role of gamma as a feedforwa

218 sed, this group of malignancies continues to pose major challenges to public health.

219 itate tumor growth and progression, and also pose major obstacles for cancer therapy.

220 Acclimation to changing light intensities poses major challenges to plant metabolism and has been

221 conditions, including cancer, but they also pose many delivery challenges.

222 nt MMP subtypes on distinct cell populations poses MMP-2,9 activity as an important mediator and cont

223 idney disease (CKD) in low-resource settings poses multiple challenges, including late diagnosis, the

224 ide adoption of whole-genome sequencing also poses new challenges for public-health agencies that mus

225 ations and highly capitalized fisheries, are posing new challenges for fisheries management.

226 whose symptoms are minimally bothersome and pose no apparent risk to driving safety, can be treated

227 attering of bromine and iodine to define the pose of these inhibitors and investigated inhibitor bind

228 e undertaken to assess the predicted binding poses of the abacavir analogues within the HLA-B*57:01 p

229 the multifaceted threats that climate change poses on migrating species.

230 Nitrogen-based fuels pose one possible synthetic fuel pathway.

231 Antibiotic resistance poses one of the greatest threats to global health today

232 ous reaction parameters, stages, and routes, poses one of the most complex challenges of modern collo

233 y acute graft-versus-host disease (SR-aGVHD) poses one of the most vexing challenges faced by provide

234 he current coronavirus disease 2019 pandemic poses particular challenges for HIV research, care, and

235 gradation of dissolved contaminants but also pose potential risks by harboring and shedding microbes

236 oteins (HCPs) present in biotherapeutics can pose potential safety risks for patients or affect produ

237 cleavage products-a class of compounds that poses potential health risks at relatively low concentra

238 radiation is a natural nonchemical stressor posing potential hazards to organisms such as planktonic

239 Posing power was further evaluated for the BRPF1 set.

240 ection of prebleaching is known to be an ill-posed problem, limiting the utility of the technique.

241 organic residue, halogens, and metals, which pose problems during recycling.

242 However, the lack of robustness assessment poses problems for their application across institutions

243 ailures to detect breeding can be difficult, posing problems for the estimation of individual reprodu

244 ysiological role of the observed alternative pose remains to be validated, our structural results hin

245 motifs, and consumption of wheat beers would pose risks for celiac patients.

246 of the current NMOSD treatments are known to pose risks to the developing fetus and only limited safe

247 However, relays pose security risks, which can be avoided by using entan

248 Rising levels of antimicrobial resistance pose serious dangers to patients, population health, foo

249 and polyfluoroalkyl substances (PFAS), which pose serious health concerns.

250 st to synthetic polymeric materials that can pose serious negative environmental impacts, cellulose-b

251 onstant concern in maize production, as they pose serious risks to human and animal health.

252 rpretation of such complex forms of big data poses serious challenges to users of MD.

253 ading cause of congenital birth defects, and poses serious risks for immuno-compromised individuals.

254 Enterovirus 71 (EV71) poses serious threats to human health, particularly in S

255 wever, treatment of COVID-19 with ACEIs/ARBs poses several challenges.

256 site for clinical islet transplantation, it poses several restrictions, especially limited tissue vo

257 ities, causes liver cancer in humans and can pose severe economic losses to farmers.

258 Powdery mildew poses severe threats to wheat production.

259 ugars, furanics, and lignin-derived monomers pose significant disadvantages in process economics.

260 ia associated with freshwater ecosystems can pose significant health risks particularly where recreat

261 tion (MR) is a complex valve lesion that can pose significant management challenges.

262 als and conventional liquid electrolytes can pose significant safety concerns.

263 Pathogens pose significant threats to pollinator health and food s

264 y, targeting these receptors therapeutically poses significant challenges including addiction, depend

265 Climate change poses significant emerging risks to biodiversity, ecosys

266 carbons in domestic-use groundwater aquifers poses significant environmental and human health concern

267 xtirpated much of Guam's native birdlife and poses significant threats to other parts of the western

268 However, direct-targeting of c-Myc poses special problem because of its non-enzymatic natur

269 fic time points during the procedure seem to pose specific risks for the genesis of aerosol and thus

270 nal straightforward simulations to determine pose-specific ligand residence times.

271 Oncogenic RAS mutations pose substantial challenges for rational drug discovery.

272 l with the ethical issues that this practice poses: termination of advanced cardiopulmonary resuscita

273 l poles, while the third, most robust, model poses that this clustering is due to a short-ranged inte

274 r, the ever penetrating GCR will continue to pose the most significant health risks especially as lun

275 already being tested in clinical trials, we pose the question: what will the vaccine hesitant do in

276 and their mass spectrometric behaviour, and poses the risk of missing unknown, potentially diagnosti

277 liver, coagulation, and circulatory failure posing the highest increased risk.

278 r invasive candidiasis, antibacterial agents posing the highest risk for Clostridioides difficile inf

279 ond and the nonpolarity of the N(2) molecule pose thermodynamic and kinetic challenges for promoting

280 Here, we pose this question in the context of a simple interdepen

281 nivores fascinate society, yet these animals pose threats to people living near them, resulting in hi

282 ells serve as important reservoirs and still pose threats to public health.

283 er susceptibility gene type 1 or 2 (BRCA1/2) poses tissue-specific variations in cancer risks and pri

284 ent in live bird markets and the threat they pose to human health.

285 by assessing the short-term risks oil spills pose to polar bears, ringed seals, and walrus in the Kar

286 ustrate the dangers that uncorrected stimuli pose to receptive field mapping experiments.

287 e the serious threat that wildlife poisoning poses to biodiversity.

288 emerging threat that microplastic pollution poses to soil and its biota necessitates the development

289 Treatment with currently available drugs poses treatment difficulties in some patients due to dru

290 We pose unanswered questions regarding HCC susceptibility a

291 ne how proton-induced conformational changes pose unique challenges to classical molecular dynamics s

292 versible covalent chemistry for base-pairing pose unique synthetic challenges.

293 irus 2 [coronavirus disease 2019 (COVID-19)] poses unique challenges for immunosuppressed patients.

294 alth of data in the electronic health record poses unique modeling challenges.

295 The rapid increase of multidrug resistance poses urgent threats to human health.

296 ), we find that eticlopride binds D(2)R in a pose very similar to that in the D(3)R/eticlopride struc

297 istance restraints, we found the near-native poses were ranked 1st, 1st and 10th among 54 000 possibl

298 ion energetics of billions of conformational poses were ranked by the programs PIPER and ClusPro.

299 cent outbreaks highlight the risk diphtheria poses when civil unrest interrupts vaccination and healt

300 ithin the steel injector body itself, we are posed with a unique challenge for imaging the flow withi