ライフサイエンスコーパス: positive feedback

1 a surge of release that triggers ovulation (positive feedback).

2 are shifted to favor increased firing during positive feedback.

3 most effective when applied to cells during positive feedback.

4 nd necessary amplification conferred by late positive feedback.

5 -sea level pressure-cloud-longwave radiation positive feedback.

6 in synthesis, 2) protein degradation, and 3) positive feedback.

7 etastable pool of Cdc42 that is sustained by positive feedback.

8 control participants compared to non-social positive feedback.

9 ack, whereas ectomycorrhizal trees displayed positive feedback.

10 recurrent network models of integration via positive feedback.

11 Although HIV circuity includes positive feedback activation of the Tat transactivator,

12 Thus, pDCs act as positive feedback amplifiers of neutrophil effector acti

13 r interactions in this system give rise to a positive feedback and bistable collective switching of R

14 able systems that are coupled through mutual positive feedback and memory.

15 n fluctuations should rapidly trigger active positive feedback and replication, precluding establishm

16 s near a stable fixed point) inherent in the positive feedback, and further identify a fundamental no

17 Negative and positive feedbacks are postulated to be mediated by kiss

18 As a result, we propose that an important positive feedback arises, whereby contracting cells draw

19 We show that positive feedback at the level of the GATA3-BMP4 axis in

20 Membrane sequestration of HdrR prevents the positive feedback autoregulatory function of HdrR, there

21 models have led to a consensus that there is positive feedback between carbon (C) fluxes and climate

22 protection options to reduce the stress from positive feedback between forest loss, climate change, a

23 arasite-induced migratory stalling" due to a positive feedback between increasing parasite burdens an

24 These results suggest that positive feedback between interacting transcriptional co

25 We hypothesize a positive feedback between iron cycling, microbial activi

26 g in the muscles, and that there is indirect positive feedback between JAK/STAT and insulin signaling

27 ion reactions were performed simultaneously, positive feedback between PI3KC3-C1 and WIPI2 led to rap

28 as/TAK1/IkappaBalpha/NF-kappaB pathway and a positive feedback between SOX9 and NF-kappaB are involve

29 triggered activity that are maintained by a positive feedback between the action potential upstroke

30 firm experimentally that the kidney-specific positive feedback between WNT11 and GDNF permits the den

31 ce-mass loss from Antarctic, potentially via positive feedbacks between the extent of exposed rock, m

32 to peer acceptance (ie, neutral response to positive feedback), but not a more negative subjective r

33 increase in ice loss from WAIS could trigger positive feedback by decreasing ice mass and increasing

34 logically-relevant parameter space where the positive feedback can dominate, even when gradients are

35 Importantly, such positive feedback can drive large fluctuations in the in

36 upon depolarization and, in turn, limits the positive-feedback cascade of excitotoxic neuronal injury

37 operations of negative/positive- or positive/positive- feedback cascades are accomplished.

38 rkets, phenomena like imitation, herding and positive feedbacks characterize the emergence of endogen

39 resistance by acquiring mutations while the positive-feedback circuit remains mutation-free and rega

40 More broadly, the results suggest that positive-feedback circuits may have evolved not only for

41 erplay between biochemical signaling through positive feedback, combined with diffusion on the cell m

42 role in focal attentional modulation through positive feedback, consistent with observations that beh

43 moving cells guided by matrix cues establish positive feedback control of rear retraction by sensing

44 y bright to measure the diffusion-controlled positive feedback current in good agreement with the the

45 The resulting positive feedback cycle escalates into bulimia for many,

46 A positive feedback cycle is triggered resulting in the fo

47 TLD showed this to be maladaptive, fueling a positive feedback cycle of enhanced neuronal tau via non

48 ticity, with the ensuing interruption of the positive feedback cycle of LTP serving as a possible cri

49 of acute respiratory distress syndrome in a positive feedback cycle, measures can be taken to interr

50 neuron excitability in all groups other than positive feedback despite different underlying conductan

51 trans-Golgi Arf-GEF, through autoinhibition, positive feedback, dimerization, and interactions with a

52 In B-cells, positive feedback-driven Ras activation is the proposed

53 ts; these transitions are probably caused by positive feedback effects between plants and microorgani

54 Our results suggest that the positive feedback effects of landscape burning can subst

55 Negative and positive feedback effects of ovarian 17beta-estradiol (E

56 Positive feedback-enabled accumulation of the nanopartic

57 Without mechanisms for interrupting positive feedback, excitatory synapses could strengthen

58 l ON-OFF expression and that transcriptional positive feedback from Tat shifts and expands the regime

59 response on the sandy loam was reinforced by positive feedbacks from aboveground net primary producti

60 intrinsic properties of GnRH neurons during positive feedback further poise these cells for increase

61 the yeast pheromone response have shown how positive feedback generates switches, negative feedback

62 le GnRH/luteinizing hormone (LH) release and positive feedback generating preovulatory GnRH/LH surges

63 The models capture these positive feedbacks, giving us improved confidence in the

64 increased it to arcuate kisspeptin neurons; positive feedback had the opposite effect.

65 two mechanisms that modulate transcriptional positive feedback in the ComRS system, where comX bimoda

66 ion to better stability of defense mRNAs and positive feedback in the IFN response amplified by RNase

67 suggested that bistability also arises from positive feedback in the regulation of the Cdk1-countera

68 We first generate synthetic negative and positive feedback in the yeast mating pathway by fusing

69 ger than those observed now, owing to strong positive feedbacks in the ice-climate system.

70 own enrichment creating a highly-responsive positive feedback, independent of biorientation.

71 hibitors reduced Xbp1 splicing, suggesting a positive feedback inhibition.

72 PSg trains mimicking positive feedback initiated more action potentials in ce

73 switch of estradiol action from negative to positive feedback initiates a surge of GnRH release, cul

74 A switch from estradiol negative to positive feedback initiates the GnRH surge, ultimately t

75 Thus, the positive feedback introduces a hierarchy among negative

76 traditional approaches such as avoidance of positive feedback iR compensation, a major issue for liq

77 mizygous donors, one model (the one with the positive feedback located at the level of gene transcrip

78 regulatory network composed of a fast-acting positive feedback loop and a delayed negative feedback l

79 dynamically enhancing plaque targeting via a positive feedback loop and dual action of cholesterol de

80 polarization is driven by the Bem1-mediated positive feedback loop and reveal novel features of its

81 hanced FKBP5 response to NF-kappaB through a positive feedback loop and was present in individuals wi

82 A physiological consequence of this positive feedback loop appears to be decreased GBM cell

83 Dynamical modeling revealed interlocking positive feedback loop architecture, which exhibits bist

84 There is also an important positive feedback loop as T(b) influences BMR(1-3).

85 Our study reveals a positive feedback loop between antigen-specific CTLs and

86 A positive feedback loop between cytoskeletal signaling an

87 Overall these results suggest a positive feedback loop between lamellar disruption and c

88 macological inhibition of Bcl6, suggesting a positive feedback loop between MLL and BCL6.

89 suggests that early-life stress initiates a positive feedback loop between peripheral inflammatory c

90 Overall, our novel data suggest that a positive feedback loop between Snail-nuclear Cat L-CUX1

91 2 is itself an AR-regulated gene, creating a positive feedback loop between the two factors.

92 ion is induced by beta-catenin, triggering a positive feedback loop between the two proteins.

93 cal-chemical integration occurring through a positive feedback loop centred on FGF20, which induces c

94 e model predicted that the stimulus-specific positive feedback loop could be responsible for the diff

95 ISPR-based methods, suggesting an amplifying positive feedback loop due to increasing gRNA dosage.

96 icroglia activation in a microglia-astrocyte positive feedback loop during brain inflammation.

97 -dependent B-Raf and ERK1/2 activation; this positive feedback loop enhances the invasion of colon ca

98 led-related protein 2 possibly establishes a positive feedback loop enhancing transforming growth fac

99 which then becomes self-sustained through a positive feedback loop established among the tumor-secre

100 wer channel activity, thereby establishing a positive feedback loop for PI(4,5)P(2) microdomain compa

101 A positive feedback loop from IL-1beta and back to PGE2, w

102 Depletion of Zeb1 disrupts this positive feedback loop in the tumor perivascular niche,

103 teins, and our results are consistent with a positive feedback loop in which amino acids bound to sel

104 y restoring EZH2 expression, thus defining a positive feedback loop in which EZH2 controls GC B cell

105 We also identified a positive feedback loop in which TGF-beta signaling promo

106 Importantly, a positive feedback loop involving autocrine LIF, LIFR, an

107 These findings demonstrate a deleterious positive feedback loop involving elevated intracellular

108 A positive feedback loop involving RAS and SOS, which lead

109 Together, these results suggest that a positive feedback loop involving sialidases potentiates

110 This positive feedback loop is thought to be important for th

111 lecules and suggest that the function of the positive feedback loop is to stabilize the oscillations

112 Here, we uncovered an NFIB-calpain 1-positive feedback loop mediated through CAST and calcine

113 MAD1-dependent pool of CDK1-CCNB1 creates a positive feedback loop necessary for timely recruitment

114 lux from the deep ocean to the atmosphere, a positive feedback loop not included in most future proje

115 adjacent cells, which is likely to create a positive feedback loop of cellular senescence within the

116 ropose a testable hypothesis that, a vicious positive feedback loop of des-Arg(9)-bradykinin- and bra

117 ced expression of GhMAPK3K15, constituting a positive feedback loop of GhWRKY59-regulated MAP kinase

118 A TaVrt2-mediated positive feedback loop of TaVrn1 during vernalization wa

119 tic stress observed in vivo and found that a positive feedback loop on protein kinase A mediated by t

120 Akt signaling and activate Dyn1 to create a positive feedback loop required for rapid recycling of E

121 s bimodal, which indicates the presence of a positive feedback loop somewhere in the regulatory envir

122 and that HIF-1alpha and iNOS are linked by a positive feedback loop that amplifies macrophage activat

123 HOCl, constitutes a potentially detrimental positive feedback loop that can only be attenuated throu

124 eractions between Spd-2, Polo and Cnn form a positive feedback loop that drives the dramatic expansio

125 id (ATRA) induces VCP expression, creating a positive feedback loop that enhances degradation.

126 Their combination constitutes a positive feedback loop that exponentially amplifies thei

127 ate that the PI3-K-->Akt pathway serves as a positive feedback loop that further enhances noncanonica

128 dynactin to the oocyte posterior, creating a positive feedback loop that increases the length and per

129 the discovery of a splice isoform-dependent positive feedback loop that is essential to sustain PI3K

130 elop therapeutic strategies that disrupt the positive feedback loop that leads to persistent airway c

131 ept of stable motif, i.e., a self-sustaining positive feedback loop that maintains an associated stat

132 ental HIF-1alpha expression, which creates a positive feedback loop that promotes FLT-1 expression le

133 further recruitment of P-TEFb, generating a positive feedback loop that sustains transcription.

134 urface-dependent lasR induction initiating a positive feedback loop through the small RNA, Lrs1.

135 ctional tight junctions, which establishes a positive feedback loop to accommodate lumen growth.

136 hydrocholesterol (7-DHC) accumulation form a positive feedback loop to amplify innate immune response

137 he lytic switch protein, thereby providing a positive feedback loop to ensure successful completion o

138 d VIC deposition of GAGs, thereby creating a positive feedback loop to further enrich GAG content and

139 d hyperactivity, demonstrating an unexpected positive feedback loop to persistently promote pain.

140 actin assembly to PI3K activation to form a positive feedback loop to support lateral membrane exten

141 ream targets including MYC and JUN, drives a positive feedback loop to up-regulate multiple other RTK

142 Chemotherapeutic drugs triggered a positive feedback loop via ATM/E2F1/STAT signaling, ampl

143 6 targeting in the plaques by establishing a positive feedback loop via the reciprocal regulation of

144 In 4T1BR5 cells, there was a positive feedback loop whereby astrocytic BDNF induced c

145 scherichia coli lac operon is regulated by a positive feedback loop whose potential to generate an al

146 cuit models differing in the location of the positive feedback loop with respect to the gene can all

147 iments revealed that Notch signaling forms a positive feedback loop with the Hippo signaling effector

148 e IL-6 in the aorta, which participates in a positive feedback loop with the impaired vascular mitoch

149 ive of specific movements is maintained by a positive feedback loop with the thalamus.

150 te of tissue damage and thereby results in a positive feedback loop, amplifying GBM necrosis developm

151 gh SigM activity results from a dysregulated positive feedback loop, and can be suppressed by overexp

152 Here, we present a novel mechanism of a positive feedback loop, formed by a reciprocally activat

153 thrombin generation acting effectively in a positive feedback loop, mediating a subsequent surge in

154 In this mutant lacking the Snf1-mediated positive feedback loop, Msn2 responds similarly to gluco

155 activity and disrupt the nuclear AURKA/FOXM1-positive feedback loop, respectively, resulting in a mor

156 Aurora B and Bub1 form a distance-dependent positive feedback loop, which spatiotemporally may act a

157 t that beta-catenin and Tspan8 are part of a positive feedback loop, which sustains a high Tspan8 exp

158 These interactions form an engine-like positive feedback loop, which sustains a shared elongati

159 ed hypoxia inside the tumor mass, creating a positive feedback loop.

160 ation post-transcriptionally, establishing a positive feedback loop.

161 undreds of genes in oncogenic pathways via a positive feedback loop.

162 uppresses AR activity and initiation of this positive feedback loop.

163 depends on its position with respect to the positive feedback loop.

164 criptional activation and ATX secretion in a positive feedback loop.

165 ACYGY, which enhance DUO1 transcription in a positive feedback loop.

166 reased killing of cancer cells, setting up a positive feedback loop.

167 romotes TNBC cell metastasis, thus forming a positive feedback loop.

168 in the hypothalamus, is a part of estrogen's positive feedback loop.

169 lation status maintained by operation of the positive feedback loop.

170 rs to be a sialidase - TGF-beta1 - sialidase positive feedback loop.

171 he mitogen-activated protein kinase ERK in a positive feedback loop.

172 tion during pDC differentiation, revealing a positive feedback loop.

173 ells upregulates IL-12 secretion by DCs in a positive feedback loop.

174 , further accelerating mass recruitment in a positive feedback loop.

175 hore distance-dependent manner, indicating a positive feedback loop.

176 itochondrial dysfunction and IL-6 exist in a positive feedback loop.

177 levels in neurons, forming a transcriptional positive feedback loop.

178 cytokine expression in macrophages through a positive feedback loop.

179 induced IL-10 production in ILC2s through a positive feedback loop.

180 y promote the recruitment of each other in a positive feedback loop.

181 da induces its own gene expression through a positive feedback loop.

182 e activity and promoting ATM activation in a positive feedback loop.

183 rotein amplifies amphiregulin signaling in a positive feedback loop.

184 ocampus, thereby establishing an associative positive-feedback loop and connecting functionally diver

185 We identified a positive-feedback loop between PPARD and interferon gamm

186 We also identified a positive-feedback loop in which ERK/EGR1 signaling promo

187 These results demonstrate a novel positive-feedback loop that links the myofibroblast phen

188 or complement initiation occurring through a positive-feedback loop wherein surface-deposited C3b par

189 3beta (GSK3beta) signaling pathway through a positive-feedback loop, resulting in N-Myc stabilization

190 posure contributes to induction of IRF5 in a positive-feedback loop.

191 ases in astrocytic Ca(2+) and resulting in a positive-feedback loop.

192 ecules might be concomitantly activated in a positive-feedback loop.

193 urther recruit T cells to the skin through a positive-feedback loop.

194 predictions for the switching properties of positive feedback loops and that these differences decre

195 The resulting positive feedback loops rapidly lock larvae into evolvin

196 ix minimal classes based on the structure of positive feedback loops that activate and localize Cdc42

197 These principles include positive feedback loops that are required to destabilize

198 ting that SARS-CoV-2 infections could create positive feedback loops that increase ACE2 levels and fa

199 We further identified two positive feedback loops that integrate epigenetic regula

200 ehavior of important pluripotency-sustaining positive feedback loops, and induce a bifurcation in the

201 reveal C/EBPdelta as a link that engages two positive feedback loops, in part by directly targeting t

202 plored tissue-specific gene activation using positive feedback loops.

203 inhibit several stages of disease-associated positive feedback loops.

204 suggest that AN may arise from pathological positive feedback loops: voluntary food restriction acti

205 ters appear to facilitate this crosstalk and positive-feedback loops between multiple types of immune

206 hese direct effects and by the disruption of positive-feedback loops between tumour cells and the bon

207 ther to propagate along the Xi, suggesting a positive feedback mechanism between RNA initiator and pr

208 We propose a positive feedback mechanism between the sea ice anomaly

209 A positive feedback mechanism between tropical cyclones (T

210 There is a novel positive feedback mechanism in epithelial LOX induction

211 calculations, we identify a molecular-scale positive feedback mechanism in which exchange of the lar

212 ) from the sarcoplasmic reticulum (SR) via a positive feedback mechanism in which fluxed Ca(2+) activ

213 S100A8 and S100A9 may participate in a positive feedback mechanism involving enhanced leukocyte

214 We speculate that the positive feedback mechanism observed during the 2017-18

215 Aggregate partitioning is caused by a positive feedback mechanism of aggregate nucleation and

216 AURKA is an AR-V target gene demonstrating a positive feedback mechanism of androgenic signalling in

217 ger the PYK2/MEK/ERK signalling pathway as a positive feedback mechanism that amplifies the TRPM2 cha

218 ated during fructose metabolism may act as a positive feedback mechanism that stimulates endogenous f

219 Our results establish a positive feedback mechanism that sustains PI3K/Akt signa

220 Our results expose a positive feedback mechanism within the C budget of fores

221 equently boosting APOL1 expression through a positive feedback mechanism.

222 ill need to modify the concept of estrogen's positive feedback mechanism.

223 heterogeneity via an FGF receptor-dependent positive feedback mechanism.

224 activity and further potentiates TRPC4 via a positive feedback mechanism.

225 the energy release via 'magnetic breakout'-a positive-feedback mechanism between filament ejection an

226 Thus, FZD3 establishes a positive-feedback mechanism that activates MAPK signal t

227 Emphasizing the positive feedback mechanisms by which gliomas increase n

228 ons, which avoid unwanted side reactions and positive feedback mechanisms that can prove problematic

229 ical consequences were sustained by a set of positive feedbacks, mediated by the oxygen and sulfur cy

230 ital ERK responses persist in the absence of positive feedback-mediated Ras activation, and digital E

231 parative images measured in the conventional positive feedback mode in quiescent solution show that h

232 These and other results suggest a positive feedback model in which LET-99 localizes to the

233 The examples include subcircuits encoding positive feedback, mutual repression, and coherent feedf

234 Despite the positive feedback nature of the activation, Ca signals a

235 ow Puromycin concentrations, the high-noise, positive-feedback network delays long-term adaptation, w

236 dback and activated in the afternoon (PM) by positive feedback; no time-of-day-dependent changes occu

237 Structural perturbations revealed: the positive feedback of AKT on IRS is responsible for the b

238 ty in anabolic zone (glucose >5.5 mmol); the positive feedback of calcium on cAMP is responsible for

239 nge factors (GEF) to effectors, generating a positive feedback of GTPase activation and membrane recr

240 -based loops are probably linked to generate positive feedback of invaders on soil systems through st

241 t spatial and temporal scales, the potential positive feedback of soil microbial respiration in respo

242 ), likely contributing to underestimation of positive feedbacks of the northern forest carbon balance

243 Taken together, these results indicate a positive feedback off Peru between the coastal warming,

244 on of carbonate rocks can exert an important positive feedback on strain localization and fluid chann

245 pe long-term plasticity introduces intrinsic positive feedback on synaptic weight changes, making the

246 hosphorylation at Serine 349, which leads to positive feedback on the Nrf2-dependent transcription of

247 e cycle period, suggesting that CV exerted a positive feedback on the unit(s) of the pattern generato

248 r results reveal a new and critical role for positive feedback onto dopamine neurons through reciproc

249 or increasing GnRH neuron firing rate during positive feedback or whether both are needed.

250 Using structurally designed hairpins, positive-feedback or negative-feedback mechanisms operat

251 eek delay, and case fatality rates exhibit a positive feedback pattern.

252 In contrast, redundant solutions may explain positive feedback, perhaps indicative of the importance

253 Here, we use a synthetic positive-feedback (PF) gene circuit integrated into hapl

254 ons exhibits long-term potentiation (LTP), a positive feedback process implicated in learning and mem

255 ion towards larger brains, consistent with a positive feedback process in the evolution of the human

256 Theory, that the Industrial Revolution was a positive feedback process wherein prosperity induced pro

257 Positive feedback provided by temporarily potentiated in

258 /TRPV4/Ca(2+) signaling axis could enforce a positive feedback regulation in gastric cancer progressi

259 of VIP in gastric cancer cells, enforcing a positive feedback regulation mechanism.

260 to KPNB1 promoter region, which indicated a positive feedback regulation of KPNB1 expression mediate

261 e define the molecular underpinnings of this positive feedback regulation that enhances neuronal sens

262 eta1-binding sequence of CCN1) disrupted the positive-feedback regulation between CCN1/alpha6beta1 an

263 e that PKCtheta plays an important role in a positive feedback regulatory loop that modulates TCR-pro

264 enhances REGgamma activity in HCC, forming a positive feedback regulatory loop.

265 h particular focus on a previously neglected positive feedback related to condensational latent heati

266 eoretical framework suggests that tripartite positive feedback relationships between soil biodiversit

267 ials in response to current injection during positive feedback relative to all other groups, which we

268 uclei are postulated to mediate negative and positive feedback, respectively.

269 ERK to MEK and RAF, placed downstream of the positive feedback, shape the temporal ERK activity profi

270 nd IL-6/JAK2/STAT3 signaling pathways form a positive feedback signaling loop that mediated the inter

271 ncovers a previously unknown tightly coupled positive feedback signalling loop between AURKA and FOXM

272 of endolysosomal trafficking resulting in a positive feedback signalling-loop.

273 nsic changes to increase firing rates during positive feedback.SIGNIFICANCE STATEMENT Infertility aff

274 obo1 endocytosis-triggered and Arf6-mediated positive-feedback strengthens the Slit response in commi

275 theory and experiment show that nonlatching positive feedback substantially dampens the inverse nois

276 ductances can produce the firing response in positive feedback, suggesting the brain has many ways to

277 this forms the basis of a strong oscillatory positive feedback system that can act in parallel with o

278 warm water below the sea surface, creating a positive feedback that increases Antarctic ice loss.

279 gnaling components and cytoskeleton-mediated positive feedback that reinforces these nanodomains into

280 Cs through FOXO1 activation and triggering a positive feedback that resembles the pathogenesis of DR.

281 ing organic matter decomposition, creating a positive feedback that will promote further warming.

282 the Amazon, their different drivers and the positive feedbacks that can lead to more fires in the re

283 olylamine drug conjugate, readily triggers a positive feedback therapeutic loop through the in situ g

284 Positive feedback through a network of interconnections

285 warming, creating a potentially substantial positive feedback to climate change.

286 ith slow turnover rates and thus amplify the positive feedback to climate change.

287 organic matter decomposition, and promote a positive feedback to climate change.

288 ons for this region, potentially acting as a positive feedback to climate warming.

289 ssions to the atmosphere, and thus trigger a positive feedback to climate warming.

290 dback on episodic GnRH/LH release as well as positive feedback to control ovulation.

291 l N cycling processes with implications of a positive feedback to global climate and emphasize the cl

292 in a type I coherent feed-forward loop with positive feedback to promote invasion.

293 ) trains in all three animal models, but the positive-feedback train was most effective when applied

294 he Northern Hemisphere average due to strong positive feedbacks unique to polar regions.

295 This model involves positive feedback whereby increased technical complexity

296 r performance costs due to their reliance on positive feedback, which generates consensus but can als

297 s to it) at finer spatial scales by creating positive feedbacks, which reverse relative productivity

298 ures, representing a potentially significant positive feedback within the climate system.

299 We also find a novel positive feedback within the coupled C-P-O-Fe cycles tha

300 erturbations that are amplified by nonlinear positive feedbacks within the internal iron and sulfur c