ライフサイエンスコーパス: positive regulation

1 plays an important role in both negative and positive regulation.

2 eucine also inhibits Lrp-mediated tos operon positive regulation.

3 ion factor is the target for Pdr13p-mediated positive regulation.

4 negative regulation (the terminator) and for positive regulation.

5 start codon are the most important for this positive regulation.

6 T pathway, we demonstrate both, negative and positive regulation.

7 ic design compared with simple or sequential positive regulation.

8 er) and site 3 (at about position +100) with positive regulation.

9 C-terminal domains of EsaR are necessary for positive regulation.

10 onstrate that these enzymes engage in mutual positive regulation.

11 strategy involving negative and cooperative positive regulation.

12 Positive regulation affected VSGs and nontelomeric pol-I

13 reveal that these mechanisms of negative and positive regulation also operate on the lagging strand.

14 d residues at the rim of Hfq interfered with positive regulation and gave mixed effects for negative

15 pression of BSAP in these cells reversed the positive regulation and inhibited J chain gene transcrip

16 ' untranslated regions of acg and Rv2623 and positive regulation associated with far upstream regulat

17 he natural Hfq binding domain is optimal for positive regulation because it recruits Hfq to the mRNA

18 Despite the reciprocal positive regulation between Fgf and Wnt, the two pathway

19 al Negative Affect, Positive Reactivity, and Positive Regulation, but not Negative Reactivity.

20 Similar positive regulation by ABA also exists for other ABA bio

21 ves negative regulation by CBP60a as well as positive regulation by CBP60g and SARD1, providing multi

22 ha subunit (product of the GPA1 gene) and to positive regulation by cell-surface pheromone receptors.

23 Surprisingly, positive regulation by CodY, unlike repression, responde

24 This is the first known case of direct positive regulation by CodY.

25 mally, WUS is regulated by a balance between positive regulation by cytokinin (CK) and negative regul

26 Positive regulation by DAF-2 on dao-1, dao-4 and dao-8 w

27 d its binding partners, Rif1p and Rif2p, and positive regulation by factors such as Ku70/80, Tel1p, a

28 , fliEFG, fliDS orf126, fleSR, and fliC) and positive regulation by FleQ, an NtrC-like transcriptiona

29 t target of long-range Shh signaling through positive regulation by Gli transcription factors, provid

30 results elucidate the main mechanism of bfrB positive regulation by IdeR and identify Lsr2 as a new f

31 wn Ikaros target genes correlates with their positive regulation by Ikaros.

32 , which has been shown to be responsible for positive regulation by iron of some V. cholerae genes.

33 s normally expressed in r5 and r6 because of positive regulation by kreisler, the mouse ortholog of v

34 show no apparent DNA damage induction, show positive regulation by LexA, and those encoding small RN

35 Moreover, both positive regulation by McaS and negative regulation by A

36 Imaging showed positive regulation by nucleotide binding also within tr

37 etic considerations support a model in which positive regulation by nucleotide binding and T286 autop

38 lve both negative autoregulation by ORF1 and positive regulation by one or more transcriptional activ

39 In addition to positive regulation by PACT, PKR activity in cells is al

40 The results demonstrate a target for positive regulation by ppGpp and suggest that the cell u

41 RpoS-dependent and RpoS-independent modes of positive regulation by ppGpp.

42 ubrerythrin (rbr) promoter also suffices for positive regulation by Ptr2 in vitro, and TBP recruitmen

43 rmal expression of cyp26 genes is subject to positive regulation by RA, our data reveal a feedback lo

44 region which is predicted to play a role in positive regulation by rsmB RNA.

45 temporally regulated operons was subject to positive regulation by the CtrA response regulator prote

46 Concordant with its positive regulation by the transcription factor Bcr1p, a

47 ce genes of Listeria monocytogenes are under positive regulation by the transcription factor PrfA.

48 gulation by intramolecular interactions, and positive regulation by two alternative partnerships.

49 Complementing this negative regulation is positive regulation conferred by four androgen-response

50 We conclude that restricted positive regulation due to VEX1 sequestration, combined

51 demonstrated distinct sequences involved in positive regulation during photoautotrophic versus chemo

52 gh alternative interaction with negative and positive regulation factors.

53 h negative regulation, and 20 microRNAs with positive regulation in PDAC.

54 eracting elements that provide both specific positive regulation in T cells and specific negative reg

55 g identified direct targets of SPL7-mediated positive regulation, including Fe SUPEROXIDE DISMUTASE1

56 rylation and subsequent NOD2 signaling, this positive regulation is countered by another E3 ubiquitin

57 tion of BCR signaling, rather than enhancing positive regulation, is critical for driving autoimmunit

58 ults indicate that p53 can contribute to the positive regulation of a promoter by protein-protein int

59 controls capBCAD expression indirectly, via positive regulation of acpA and acpB.

60 reporter assays implicated DeltaNp63alpha in positive regulation of AKT1 transcription.

61 tical roles of AlcR and alcaligin inducer in positive regulation of alcaligin siderophore biosynthesi

62 cer sensing and responsiveness necessary for positive regulation of alcaligin system gene expression.

63 Fur positive regulation of all these genes is fully reversed

64 We show that the positive regulation of AM colonization via ABA requires

65 Soluble CD23 plays a role in the positive regulation of an IgE response.

66 dox signaling plays an important role in the positive regulation of angiogenesis by vascular endothel

67 d rat vascular smooth muscle cells, revealed positive regulation of Axl mRNA expression by thrombin o

68 lymphocytes that has been implicated in the positive regulation of B cell growth and antibody produc

69 nctions of Fc receptor-like (FCRL) 1 include positive regulation of BCR-induced calcium flux, prolife

70 ential processes, including acute and direct positive regulation of beta-adrenergic responsiveness.

71 Interestingly, positive regulation of beta-H/C by Stk1 requires the two

72 Concomitant negative and positive regulation of beta2 integrin-independent and be

73 ted the molecular mechanism of IdeR-mediated positive regulation of bfrB, the gene encoding the major

74 BRM23, indicating that hurI is required for positive regulation of bhu gene expression.

75 e activation, supporting the hypothesis that positive regulation of bhuRSTUV occurs by a surface sign

76 ix component with functions that include the positive regulation of bone formation.

77 thways associated with skeletal development, positive regulation of bone mineralization, and wound he

78 sr1 knockout mouse are mostly related to the positive regulation of bone remodeling and inflammatory

79 Intriguingly, loss of the positive regulation of BRCA1 leads to increased oncogeni

80 egion was determined to be important for the positive regulation of BRCA1 transcription.

81 While positive regulation of c-Akt (also known as protein kina

82 renergic receptor pathway is crucial for the positive regulation of cardiac L-type currents; however

83 This multifaceted mechanism allows positive regulation of Cav2.1 in response to local Ca2+

84 ation of transferase activity, angiogenesis, positive regulation of cell division, and cell adhesion

85 Positive regulation of cell migration by chemotactic fac

86 and reparative proteins that are involved in positive regulation of cell proliferation, response to s

87 Although it has mostly been associated with positive regulation of chromatin accessibility and gene

88 sistent with the role of the Ada proteins in positive regulation of CLN3, deletion of RPD3, encoding

89 ules, including an RNA molecule required for positive regulation of conjugation functions.

90 f FLT3-ITD(+) AML through, at least in part, positive regulation of constitutive FLT3 activation.

91 While positive regulation of contractility is well characteriz

92 nalyses confirm the synergistic negative and positive regulation of cotton drought resistance through

93 Similar positive regulation of cyclin D1 expression by CtIP was

94 TPA causes positive regulation of Cyr61 expression in ER-positive M

95 Enrichment analysis revealed malaria, positive regulation of cytokine production and positive

96 novel role for ECM-driven endocytosis in the positive regulation of cytokine signalling.

97 GdpS' positive regulation of DAG kinase function was dependent

98 Interestingly, whereas positive regulation of DNA end joining requires the comb

99 products of these genes are required for the positive regulation of dor expression in response to DMS

100 conserved role of Abl family members in the positive regulation of Dsh activity toward Fz-Dsh/PCP si

101 ic ductal adenocarcinoma (PDA) through their positive regulation of E-cadherin and maintenance of the

102 This article demonstrates that positive regulation of E16 splicing can be mediated by F

103 cient for interaction with Elongin C and for positive regulation of Elongin A transcriptional activit

104 mediated neuromodulation, from a negative to positive regulation of excitatory glutamatergic transmis

105 This is the first example of positive regulation of exon inclusion by PTB.

106 Among genes implicated in the positive regulation of FcepsilonRI signaling, mRNA for t

107 h up-regulation of STAT5 phosphorylation and positive regulation of forkhead box p3 expression.

108 d transition to flowering occurs through the positive regulation of FUL/LFY homologs.

109 fects of PKCdelta can be extended to include positive regulation of G(1) phase cell cycle progression

110 We propose that GATApal is important for positive regulation of GATA-1 expression in erythroid ce

111 have provided insights into the mechanism of positive regulation of gene activity.

112 In contrast to its corepressor function, positive regulation of gene expression by G9a involved G

113 esponse to GCs is partially dependent on the positive regulation of gene expression by GR.

114 Positive regulation of gene expression by the yeast Sacc

115 ve regulation of Foxo1 expression and direct positive regulation of Gfi1b expression.

116 To study the positive regulation of GJ assembly, fibroblasts derived

117 rts tumor glucose metabolism in part through positive regulation of glycolysis and the nonoxidative p

118 ll lines and in transgenic mice that mediate positive regulation of GnRH by Kiss.

119 P-induced HepG2 cells may be associated with positive regulation of GSH levels and antioxidant enzyme

120 rans and that it plays a central role in the positive regulation of heat shock genes.

121 ment and cellular response to interleukin-8, positive regulation of hippocampal neuron apoptotic proc

122 of hippocampal neuron apoptotic process, and positive regulation of hippocampal neuron apoptotic proc

123 uggest a role for heat shock proteins in the positive regulation of HSF2.

124 ion, is neither necessary nor sufficient for positive regulation of hsp26 when GAGA factor-binding si

125 tion stabilizes PML and is correlated with a positive regulation of IFN signaling.

126 gE and mCD21 cooperate in the sCD23-mediated positive regulation of IgE synthesis on cells committed

127 Positive regulation of Ih by prostaglandins produced dur

128 e predominant cytokine induced by IL-12, and positive regulation of IL-12 by IFN-gamma, if unchecked,

129 Positive regulation of ILC-2s through ICOS has been rece

130 knowledge, this is the first example of the positive regulation of inflammasome activation.

131 iver injury and most studies have focused on positive regulation of innate immunity.

132 Gene set enrichment analysis identified a positive regulation of interferon signaling and negative

133 This investigation uncovered positive regulation of iron storage as a critical aspect

134 sons why these mutations lead to negative or positive regulation of JAK1 are provided.

135 ffinity for ATP inhibition thus underlie the positive regulation of K(ATP) channels by PKA phosphoryl

136 apoptosis, regulation of cell proliferation, positive regulation of kinase activity, positive regulat

137 gen receptor, Fyn plays an essential role by positive regulation of Lck activity.

138 nversely, TOC1 appears to participate in the positive regulation of LHY and CCA1 expression.

139 indicated that miR-16-5p was involved in the positive regulation of lncRNA UCA1 on the expression and

140 To delineate the role of SHP-1 in positive regulation of LPS-induced IL-10 production, sig

141 Although LPS-mediated positive regulation of mA3 mRNA occurs through TLR4/TRIF

142 ealed multicellular organism development and positive regulation of macromolecule metabolic process t

143 not only stimulates but also antagonizes the positive regulation of many genes in the igaA mutant.

144 nteracting regions, and found them linked to positive regulation of mesenchymal cell proliferation in

145 sitive regulation of cytokine production and positive regulation of mitogen-activated protein kinase

146 t its effect on the HCV life cycle by way of positive regulation of MT dynamics.

147 of NF-kappaB target genes and IKK2-dependent positive regulation of MTA2 leads to activation of NF-ka

148 S5a thus appears to promote the positive regulation of myogenic genes through ubiquitin-

149 as an inhibitory receptor of neutrophils via positive regulation of NADPH oxidase activation and ROS

150 In addition, the positive regulation of NOL7 by c-Myc and RXRalpha provid

151 ontrols RNA-directed DNA methylation through positive regulation of noncoding RNAs.

152 for new components that are involved in the positive regulation of nuclear gene expression by light

153 /BMP signaling as a new pathway critical for positive regulation of nutrient storage and energy homeo

154 mammalian target of rapamycin (mTOR) in the positive regulation of oncogenesis has been well documen

155 ce of the divalent cations, resulting in the positive regulation of other cell adhesion molecules and

156 trategies designed to tip the balance toward positive regulation of p28 induction by mycobacteria cou

157 chanism for the involvement of DNA-PK in the positive regulation of p50 NF-kappaB to drive VCAM-1 exp

158 ultiple ETS-binding sites and demonstrated a positive regulation of PARP by ETS1.

159 ent, novel role in tube expansion, involving positive regulation of Paxillin.

160 sentiality of the VicRK TCS results from its positive regulation of PcsB expression.

161 onse regulator (RR) is essential through its positive regulation of pcsB, which encodes an extracellu

162 y at fast growth rates and demonstrated that positive regulation of pdxB occurs at the level of trans

163 ng PP1 function in plasticity, including its positive regulation of PP1 function in vivo in memory fo

164 mTOR signaling suppresses apoptosis through positive regulation of PP5 activity and suppression of c

165 Finally, there is positive regulation of PRC1 components by the ESC-E(Z) c

166 K)-3beta promotes cell proliferation through positive regulation of protein synthesis.

167 endent role of homodimerized p85alpha in the positive regulation of PTEN stability and activity.

168 he autoregulation of PrgX expression and for positive regulation of Qa RNA.

169 However, molecules required for positive regulation of Rheb have not been identified.

170 The small RNA-dependent, positive regulation of RNase BN in exponential-phase cel

171 In contrast, results suggest that positive regulation of rpoS by DsrA occurs by formation

172 mall RNAs, DsrA and RprA, participate in the positive regulation of RpoS translation.

173 rement was independent of small RNA-mediated positive regulation of RpoS translation.

174 that Pip orchestrates defense amplification, positive regulation of salicylic acid biosynthesis, and

175 ntrolled cell division is mediated under the positive regulation of secretory protein that possesses

176 This is achieved by positive regulation of septum production and negative re

177 more, we found that Fps1p is involved in the positive regulation of Sho1p function and plays a role i

178 transgenic lines were used to confirm their positive regulation of shoot Pi concentrations, under bo

179 a (miR-34a) in the liver, which results in a positive regulation of SIRT1 levels.

180 of genes by this sRNA is responsible for the positive regulation of some genes by Fur.

181 tion by modulating Wnt signaling through the positive regulation of Sostdc1.

182 ) proteins have often been implicated in the positive regulation of splicing, recent studies have sho

183 nteractions played a mechanistic role in the positive regulation of STAT3 transcription from syntheti

184 ession and silencing assays demonstrated its positive regulation of tea plant resistance.

185 Thus, positive regulation of telomerase by Est1 appears to be

186 e, suggesting that AtPot1 contributes to the positive regulation of telomere length control.

187 Negative and positive regulation of TFIIH requires phosphorylation wi

188 Positive regulation of TGFbeta1 production, regulation o

189 o enhanced type I and III IFN production and positive regulation of the anti-viral response.

190 dication of this large protein family to the positive regulation of the antiviral response, which sup

191 stent with a dominant role of PERIOD2 in the positive regulation of the Bmal1 loop.

192 s at the level of transcription and involves positive regulation of the capsule biosynthetic operon c

193 R. sphaeroides is intimately involved in the positive regulation of the cbbI and cbbII Calvin cycle C

194 The sigma 28-mediated positive regulation of the class II operons involved a m

195 proliferation by Cbl is associated with its positive regulation of the coordinated multiubiquitinati

196 3 in estradiol signaling requires the direct positive regulation of the expression of the ER alpha ge

197 However, the combined positive regulation of the feoABC operon by ArcA and FNR

198 tor protein (CRP) is shown to be involved in positive regulation of the gcv operon.

199 rain development over time and space through positive regulation of the Gli activators (GliA) and inh

200 has been shown to play a central role in the positive regulation of the heat shock operons groESL and

201 showed increased renal T-cell activation and positive regulation of the immune response.

202 p1 binding site that acts as a major site of positive regulation of the NDRG1 promoter by hypoxia sig

203 The positive regulation of the NF-kappaB-signaling pathway i

204 eage 'choice' was mediated in part by direct positive regulation of the transcription factor Th-POK.

205 While much has been discovered about positive regulation of these receptors by coactivators l

206 of Elk-1-dependent transcription, indicating positive regulation of this early response gene by Akt.

207 ssibly related to abnormal posttranslational positive regulation of this enzyme.

208 ulates T-cell activation, in contrast to the positive regulation of this process by EGR1.

209 activity, confirming the role of PU.1 in the positive regulation of this well known signaling molecul

210 The positive regulation of TLR2 induction by TGF-betaR is me

211 In contrast to the relative known positive regulation of TLR2 signaling, its negative regu

212 dation activity by bound nucleotide, and the positive regulation of transamidation by Ca2+.

213 rmine the role of ppGpp in both negative and positive regulation of transcription initiation during e

214 The enrichment for positive regulation of transcription, cell proliferation

215 tion of histone H3 (H3K4me), associated with positive regulation of transcription.

216 macrophages confirmed a role for MSK in the positive regulation of transcription.

217 l a molecular mechanism for the negative and positive regulation of transcriptional elongation at the

218 expressed genes, suggesting a nearly global positive regulation of transcriptional initiation with t

219 ion, positive regulation of kinase activity, positive regulation of transferase activity, angiogenesi

220 Overlapping responses included positive regulation of trehalose and sucrose metabolism

221 EGFR2, also appears to be under a direct and positive regulation of TTF-1.

222 that microRNA-33a (miR-33a) is under direct positive regulation of TTF-1.

223 semination are due, at least in part, to its positive regulation of tumor-host interactions that gene

224 ining the molecular mechanism underlying the positive regulation of virulence traits by CsrA.

225 HuR's positive regulation of WEE1 increases gamma-H2AX levels,

226 In this study, we define a mechanism for positive regulation of YAP activity that is critical for

227 ompelling evidence that negative, as well as positive, regulation of Ycf1p is mediated by phosphoryla

228 F126 in promoting HR-mediated repair through positive regulation on BRCA1 expression by direct intera

229 on of FOXM1/MAT2A/2B, which exert reciprocal positive regulation on each other transcriptionally.

230 /S and PmrA/B Two Component Systems confer a positive regulation on expression of the ankB gene, wher

231 protein levels showed that FlgKL inhibit the positive regulation on flgM translation by FlgN when sec

232 stress and cell apoptosis activities through positive regulation on superoxidase, malondialdehyde, ca

233 85-5p effect on VEGF-A was reversed via AR's positive regulation on the HIF2alpha-increased VEGF-A ex

234 port the idea that the VicR RR exerts strong positive regulation on the transcription of a set of gen

235 compared with WT, suggest the presence of a positive regulation pathway for thiol biosynthesis that

236 In addition to the positive regulation previously associated with DevR (Dos

237 f the fimA gene, indicating the existence of positive regulation regions.

238 zation of hBVR promoter and its negative and positive regulation, respectively, by TNF-alpha and hypo

239 ns which may be involved in the negative and positive regulation, respectively, of the mouse Ron gene

240 We have suggested that the positive regulation results from indirect effects on exp

241 es with negative regulation, five genes with positive regulation, seven microRNAs with negative regul

242 indicates the H14 couplings are stronger for positive regulation than for negatively regulated p53REs

243 They were more defective for positive regulation than negative regulation at low mRNA

244 ithin the minimal enhancer reveals a complex positive regulation that includes sites required for glo

245 to the pleiotropic stimuli that lead to its positive regulation, the known signaling mechanisms that

246 or negative regulation by Ca2+ signaling and positive regulation through co-activation of adenylyl cy

247 s were associated with negative, rather than positive, regulation under some conditions.

248 Positive Reactivity, Negative Reactivity and Positive Regulation (upregulating positive emotion to ne

249 via an associated regulatory protein and to positive regulation via phosphorylation, although target

250 Positive regulation was observed with conditioned media

251 he presence of features of both negative and positive regulation which included the CIRCE element and

252 ell-specific gene expression is solely under positive regulation, with no evidence for spore-specific