ライフサイエンスコーパス: positive-strand RNA virus

1 helicase in (-) strand genome synthesis of a positive strand RNA virus.

2 e largest replicase polyprotein of any known positive-strand RNA virus.

3 fling of viral envelope genes to attenuate a positive-strand RNA virus.

4 ic restriction mechanism of retroviruses and positive-strand RNA viruses.

5 for the production of viral small RNAs from positive-strand RNA viruses.

6 rug design and provide a precedent for other positive-strand RNA viruses.

7 NA genomes and the RNA genomes of many other positive-strand RNA viruses.

8 , that are conserved among orthologs of many positive-strand RNA viruses.

9 lex assembly for BMV, and possibly for other positive-strand RNA viruses.

10 resents a critical step in the life cycle of positive-strand RNA viruses.

11 ember of the Nodaviridae, a family of small, positive-strand RNA viruses.

12 s evolution, which works especially well for positive-strand RNA viruses.

13 aled unexpected similarities with virions of positive-strand RNA viruses.

14 cellular membranes is a universal feature of positive-strand RNA viruses.

15 olved during infection and disease caused by positive-strand RNA viruses.

16 ication complexes (RCs), by analogy to other positive-strand RNA viruses.

17 , similar to structures found for many other positive-strand RNA viruses.

18 egral membrane replicase proteins from other positive-strand RNA viruses.

19 havirus-like superfamily of animal and plant positive-strand RNA viruses.

20 lass of antiviral agents, especially against positive-strand RNA viruses.

21 phaviruses are a well-characterized group of positive-strand RNA viruses.

22 nelles (VROs) is critical for replication of positive-strand RNA viruses.

23 lized to intracellular structures typical of positive-strand RNA viruses.

24 merase structure and mechanism common to all positive-strand RNA viruses.

25 potently facilitate replication of specific positive-strand RNA viruses.

26 nd exerts antiviral activity towards several positive-strand RNA viruses.

27 understanding, controlling, and engineering positive-strand RNA viruses.

28 antiviral target, as it is hijacked by many positive-strand RNA viruses.

29 en that belongs to the Potyviridae family of positive-strand RNA viruses.

30 ar membranes are critical for replication of positive-strand RNA viruses.

31 the mechanisms underlying the replication of positive-strand RNA viruses.

32 ed, the first step of gene expression by all positive-strand RNA viruses.

33 to develop nucleoside analogs against other positive-strand RNA viruses.

34 ity of TRIM56's antiviral activities against positive-strand RNA viruses.

35 olymerase (BVDV RdRp) and RdRps from related positive-strand RNA viruses.

36 y insights into the role of recombination in positive-strand RNA viruses.

37 -shaping machinery among different groups of positive-strand RNA viruses.

38 n may be a general replication mechanism for positive stranded RNA viruses.

39 ts is the first such demonstration among all positive-stranded RNA viruses.

40 the RNA-dependent RNA polymerases of diverse positive-stranded RNA viruses.

41 ntial permissivity to replication of several positive-stranded RNA viruses.

42 matic infections, also contained one or more positive-strand RNA viruses (Aichi virus, astrovirus, or

43 Dengue virus is a positive-strand RNA virus and a member of the genus Flav

44 Bovine viral diarrhea virus (BVDV) is a positive-strand RNA virus and a member of the genus Pest

45 Poliovirus is a positive-strand RNA virus and the prototypical member of

46 re a genus within the Flaviviridae family of positive-strand RNA viruses and are transmitted principa

47 at are genetically and serologically related positive-strand RNA viruses and cause epidemics on a glo

48 er of hepatocyte-intrinsic immunity to these positive-strand RNA viruses and identify previously unre

49 Our data may serve as a paradigm for other positive-strand RNA viruses and provide a starting point

50 iew, we focus on picornaviruses, a family of positive-strand RNA viruses, and discuss the mechanisms

51 s and factors involved in the replication of positive stranded RNA viruses are still unclear.

52 Plant positive-strand (+)RNA viruses are intracellular infecti

53 Self-amplifying messenger RNA (mRNA) of positive-strand RNA viruses are effective vectors for in

54 Positive-strand RNA viruses are important pathogens of h

55 Positive-strand RNA viruses are known to rearrange the e

56 Viral replicases of many positive-strand RNA viruses are membrane-bound complexes

57 Although helicases encoded by positive-strand RNA viruses are necessary for RNA genome

58 Positive-strand RNA viruses are the largest virus class

59 To better understand how positive-strand (+) RNA viruses assemble membrane-associ

60 All positive-strand RNA viruses assemble their RNA replicati

61 replication of human rhinovirus 2 (HRV2), a positive-stranded RNA virus belonging to the Picornaviri

62 we used the ability of the higher eukaryotic positive-strand RNA virus brome mosaic virus (BMV) to re

63 Like many positive-strand RNA viruses, brome mosaic virus (BMV) RN

64 Positive-strand RNA viruses build extensive membranous r

65 Positive-strand RNA viruses build large viral replicatio

66 cludes replication enzymes commonly found in positive-strand RNA viruses, but also a set of RNA-proce

67 uses to support cell-to-cell movement of two positive-stranded RNA viruses by using trans-complementa

68 This arthropod-borne positive-strand RNA virus causes acute and fatal encepha

69 Positive-strand RNA viruses co-opt organellar membranes

70 The nidoviruses are an order of positive-stranded RNA viruses, comprising coronaviruses

71 es with either DEN or Sindbis virus, another positive-strand RNA virus, confirmed the early vs late n

72 Many positive-stranded RNA viruses contain short, single-stra

73 However, none of the positive-strand RNA viruses could be causally associated

74 As a positive-strand RNA virus, dengue virus relies on the ho

75 g TBSV replication.IMPORTANCE Replication of positive-strand RNA viruses depends on recruitment of ho

76 IMPORTANCE The replication of positive-strand RNA viruses depends on the biogenesis of

77 of virus replication complexes for all known positive-strand RNA viruses depends on the extensive rem

78 Infection with many positive-strand RNA viruses dramatically remodels cellul

79 Notably, for a range of positive-strand RNA viruses embodying many major differe

80 Many positive strand RNA viruses encode helicases, but their

81 iridae and Potyviridae families of the plant positive-strand RNA viruses encode one or two papain-lik

82 Brome mosaic virus (BMV), a positive-strand RNA virus, encodes two replication prote

83 ember of the alphavirus-like super-family of positive-strand RNA viruses, encodes two proteins requir

84 member of the alphavirus-like superfamily of positive-strand RNA viruses, encodes two proteins, 1a an

85 Positive-strand RNA viruses encompass a variety of estab

86 Positive-strand RNA viruses encompass more than one-thir

87 Mammalian positive-stranded RNA viruses establishing persistence t

88 s, members of the Arteriviridae (a family of positive-stranded RNA viruses) express their replicase p

89 Positive-stranded RNA viruses extensively remodel host c

90 Genomes of positive-strand RNA viruses fold into high-order RNA str

91 somal frameshifting (-1 PRF) is used by many positive-strand RNA viruses for translation of required

92 sly that replication complexes of some other positive-strand RNA viruses form on membrane invaginatio

93 astructural features with RNA replication of positive-strand RNA viruses from other families.

94 Positive-strand RNA viruses generally replicate in large

95 Many positive-strand RNA viruses generate 3'-coterminal subge

96 Positive-strand RNA virus genome replication is invariab

97 Positive-strand RNA virus genome replication occurs in m

98 Positive-strand RNA virus genomes are substrates for tra

99 Positive-strand RNA virus genomes are translated into po

100 In contrast, many positive-strand RNA virus genomes lack a 5'cap and promo

101 The 5'-untranslated region of positive-strand RNA viruses harbors many cis-acting RNA

102 In the absence of a 5' cap, plant positive-strand RNA viruses have evolved a number of dif

103 As a positive-strand RNA virus, hepatitis E virus (HEV) produ

104 Like most positive-strand RNA viruses, hepatitis C virus (HCV) is

105 Like other positive-strand RNA viruses, hepatitis C virus (HCV) is

106 on protein 1a of brome mosaic virus (BMV), a positive-strand RNA virus in the alphavirus-like superfa

107 Brome mosaic virus (BMV), a positive-strand RNA virus in the alphavirus-like superfa

108 Brome mosaic virus (BMV), a positive-strand RNA virus in the alphavirus-like superfa

109 Brome mosaic virus (BMV), a positive-strand RNA virus in the alphavirus-like superfa

110 Brome mosaic virus (BMV), a positive-strand RNA virus in the alphavirus-like superfa

111 in of human noroviruses (HuNoVs), a group of positive-strand RNA viruses in the Caliciviridae family

112 Therefore, CoVs are a paradox among positive-strand RNA viruses in the sense that they use b

113 Positive-strand RNA viruses include a large number of hu

114 Replication by many positive-strand RNA viruses includes genomic RNA amplifi

115 eral unique features not found previously in positive-strand RNA viruses, including the fact that it

116 s, TRIM56 is a restriction factor of several positive-strand RNA viruses, including three members of

117 iven translation, which is operative in many positive-stranded RNA viruses, including all picornaviru

118 , C19orf66) as a potent inhibitor of diverse positive-stranded RNA viruses, including multiple member

119 Positive-strand RNA viruses induce the biogenesis of uni

120 antibody staining in double-stranded DNA and positive-strand RNA virus infections but not in negative

121 This positive strand RNA virus is remarkably efficient at est

122 This positive-strand RNA virus is remarkably efficient at est

123 The replication of positive-strand RNA viruses is a complex multi-step proc

124 RNA recombination in positive-strand RNA viruses is a molecular-genetic proce

125 IMPORTANCE Replication of positive-strand RNA viruses is affected by the recruitme

126 RNA replication of all positive-strand RNA viruses is closely associated with i

127 A-dependent RNA polymerase (RdRp) encoded by positive-strand RNA viruses is critical to the replicati

128 Replication of all positive-strand RNA viruses is intimately associated wit

129 One characteristic of all positive-strand RNA viruses is the necessity to assemble

130 l to the replication of poliovirus and other positive-strand RNA viruses is the virally encoded RNA-d

131 protein processing of dengue virus type 2, a positive strand RNA virus, is carried out by the host si

132 ection by human astrovirus (HAstV), a small, positive-strand RNA virus, is a major cause of gastroent

133 Hepatitis C virus (HCV), a positive-strand RNA virus, is the major infectious agent

134 the HEV replicase, similar to those of other positive-strand RNA viruses, is also involved in virus p

135 ral RNA progeny in infected cells of several positive-strand RNA viruses, is initially inactive.

136 As the other positive-strand RNA viruses, it is believed to replicate

137 RNAs of many positive strand RNA viruses lack a 5' cap structure and

138 on protein 1a of brome mosaic virus (BMV), a positive-strand RNA virus, localizes to the cytoplasmic

139 for the involvement of host phospholipids in positive-strand RNA virus membrane-specific targeting.

140 These positive-strand RNA viruses might be direct ancestors of

141 Positive-stranded RNA virus movement proteins (MPs) gene

142 Replication of positive-strand RNA viruses occurs in tight association

143 cation of tomato bushy stunt virus (TBSV), a positive-strand RNA virus of plants.

144 IMPORTANCE Enterovirus A71 (EV-A71), a positive-strand RNA virus of the Picornaviridae, poses a

145 lication, a widely conserved mechanism among positive-strand RNA viruses of diverse origin.

146 All positive-strand RNA viruses of eukaryotes studied assemb

147 cids are conserved across all polymerases of positive-strand RNA viruses of eukaryotes.

148 mechanism that appears to be conserved among positive-strand RNA viruses of plants (this study), anim

149 The majority of positive-strand RNA viruses of plants replicate and sele

150 Positive-strand RNA viruses of the order Nidovirales hav

151 Brome mosaic virus, a tripartite positive-stranded RNA virus of plants, was used for the

152 ts in brome mosaic virus (BMV), a tripartite positive-stranded RNA virus of plants.

153 Bovine viral diarrhea virus (BVDV) is a positive-stranded RNA virus of the Flaviviridae family.

154 Positive-stranded RNA viruses of plants use their RNAs a

155 a means of solving the "problem," common to positive strand RNA viruses, of competition between ribo

156 The coat protein of positive-stranded RNA viruses often contains a positivel

157 bditis elegans and its natural pathogen, the positive-strand RNA virus Orsay, have recently emerged a

158 bditis elegans and its natural pathogen, the positive-strand RNA virus Orsay, have recently emerged a

159 avirus-like superfamily, as well as in other positive-strand RNA viruses pathogenic to humans (e.g.,

160 (MeV) uses tissue-specific nectin-4, and the positive-strand RNA virus poliovirus uses nectin-like 5

161 By using a positive-strand RNA virus, porcine reproductive and resp

162 IMPORTANCE Many positive-strand (+) RNA viruses produce long noncoding R

163 eract and avoid error catastrophe.IMPORTANCE Positive-strand RNA viruses produce vast amounts of prog

164 Comparison with other positive-strand RNA viruses producing multiple subgenomi

165 ing residues that are highly conserved among positive-strand RNA virus RdRPs.

166 We studied the Orsay virus, a positive-strand RNA virus related to Nodaviridae and the

167 Positive strand RNA viruses replicate via a virally enco

168 Positive-strand (+)RNA viruses replicate in the cytosol

169 Characterized positive-strand RNA viruses replicate in association wit

170 imilar to animal viruses, the abundant plant positive-strand RNA viruses replicate in infected cells

171 All positive-strand RNA viruses replicate their genomes in a

172 Positive-strand RNA viruses replicate their genomes in v

173 Positive-strand RNA viruses replicate their genomes on i

174 Positive-strand RNA viruses replicate their genomes on m

175 Positive-strand RNA viruses replicate their genomes usin

176 However, most positive-strand RNA viruses replicate within a modified

177 tive-strand RNA viruses, similarly to animal positive-strand RNA viruses, replicate in membrane-bound

178 Rubella virus (RUBV), a positive-strand RNA virus, replicates its RNA within mem

179 esults provide new mechanistic insights into positive-strand RNA virus replication compartment struct

180 Positive-strand RNA virus replication complexes are univ

181 ular membrane rearrangements associated with positive-strand RNA virus replication in cells.

182 ng to map critical host pathways restricting positive-strand RNA virus replication in immortalized he

183 Biochemical studies suggest that positive-strand RNA virus replication involves host as w

184 ization of host cell membranes essential for positive-strand RNA virus replication should provide ins

185 mosaic virus (BMV) has served as a model for positive-strand RNA virus replication, recombination, an

186 ed functions required for different steps of positive-strand RNA virus replication.

187 The mechanisms that direct positive-stranded RNA virus replication complexes to pla

188 Like other positive-strand RNA viruses, replication of hepatitis C

189 Positive-strand RNA viruses represent a major class of h

190 rabidopsis thaliana defense against distinct positive-strand RNA viruses requires production of virus

191 Positive-strand RNA viruses reshape the intracellular me

192 Here, we show that hepatitis A virus, a positive-strand RNA virus responsible for infectious hep

193 ture-function relationships and suggest that positive-strand RNA viruses retain a unique palm domain-

194 The universal membrane association of positive-strand RNA virus RNA replication complexes is i

195 Positive-strand RNA virus RNA replication is invariably

196 The replication of many positive-strand RNA viruses [(+)RNA viruses] depends on

197 All well-characterized positive-strand RNA viruses[(+)RNA viruses] induce the f

198 us (HAV) and hepatitis C virus (HCV) are two positive-strand RNA viruses sharing a similar biology, b

199 Plant positive-strand RNA viruses, similarly to animal positiv

200 During infection, positive-strand RNA viruses subvert cellular machinery i

201 IMPORTANCE Positive-strand RNA viruses such as HCV represent a sign

202 Positive-strand RNA viruses such as poliovirus replicate

203 Both positive-strand RNA virus supergroups, coronaviruses and

204 Brome mosaic bromovirus (BMV), a positive-stranded RNA virus, supports both homologous an

205 nternational Herpesvirus Workshop (IHW), the Positive-Strand RNA Virus Symposium (PSR), and the Gordo

206 Rubivirus genus in the Togaviridae family of positive-strand RNA viruses, synthesizes a single subgen

207 Barley Yellow Dwarf Virus (BYDV) is a positive strand RNA virus that lacks the canonical 5' 7-

208 Flock House virus (FHV; Nodaviridae) is a positive-strand RNA virus that encapsidates a bipartite

209 Mouse hepatitis virus (MHV) is a 31-kb positive-strand RNA virus that is replicated in the cyto

210 Hepatitis C virus (HCV) is a positive-strand RNA virus that primarily infects human h

211 Hepatitis C virus (HCV) is a positive-strand RNA virus that remains one of the main c

212 Hepatitis C virus (HCV) is a positive-strand RNA virus that replicates exclusively in

213 ncephalitis virus (WEEV) are arthropod-borne positive-strand RNA viruses that are capable of causing

214 In contrast to other positive-strand RNA viruses that block IFN induction by

215 Alphaviruses are positive-strand RNA viruses that can mediate efficient c

216 RS-CoV), is a member of this large family of positive-strand RNA viruses that cause a spectrum of dis

217 inovirus (HRV), like coronavirus (HCoV), are positive-strand RNA viruses that cause both upper and lo

218 Human rhinoviruses (RVs) are positive-strand RNA viruses that cause respiratory tract

219 Flaviviruses are insect-borne, positive-strand RNA viruses that have been disseminated

220 rnaviridae are a large and diverse family of positive-strand RNA viruses that includes hepatitis A vi

221 The Picornaviridae are a diverse family of positive-strand RNA viruses that includes numerous human

222 The Coronaviridae is a family of positive-strand RNA viruses that includes SARS-CoV-2, th

223 viruses (DENV) comprise a family of related positive-strand RNA viruses that infect up to 100 millio

224 our findings suggest the existence of novel positive-strand RNA viruses that probably replicate in h

225 Poliovirus, like all positive-strand RNA viruses that replicate in the cytopl

226 Coronaviruses are positive-strand RNA viruses that translate their genome

227 Hepatitis C virus (HCV) is the only known positive-stranded RNA virus that causes persistent lifel

228 Hepatitis C virus (HCV) is a positive-stranded RNA virus that causes severe liver dis

229 West Nile virus (WNV) is an enveloped positive-stranded RNA virus that has emerged over the pa

230 Arteriviruses are economically important positive-stranded RNA viruses that encode an ovarian tum

231 the movement of MP-defective mutants of two positive-stranded RNA viruses that have different moveme

232 Unlike its antiviral actions against positive-strand RNA viruses, the anti-influenza virus ac

233 In positive-strand RNA viruses, the genome serves as a temp

234 Positive-strand RNA viruses, the largest genetic class o

235 Positive-strand RNA viruses, the largest genetic class o

236 Like other positive-strand RNA viruses, the Turnip mosaic virus (Tu

237 iral RNA as a template during replication of positive-stranded (+)RNA viruses, the RNA also has cruci

238 for members of the Picornaviridae family of positive-strand RNA viruses, their successful replicatio

239 In the case of positive-strand RNA viruses, this represents a particula

240 origin accumulate in cells infected by many positive-strand (+) RNA viruses to bolster viral infecti

241 iously demonstrated the intrinsic ability of positive-strand RNA viruses to escape this selective pre

242 emonstrate a potential novel mechanism for a positive-stranded RNA virus to regulate viral translatio

243 Similar to other positive-strand RNA viruses, tombusviruses are replicate

244 Positive-strand RNA viruses typically utilize host intra

245 The genomes of positive-strand RNA viruses undergo conformational shift

246 Genomes of positive (+)-strand RNA viruses use cis-acting signals t

247 Positive-strand RNA viruses use long open reading frames

248 Brome mosaic virus (BMV) is a tripartite positive-strand RNA virus used to study the requirements

249 Positive-strand RNA viruses utilize various subcellular

250 irus, poliovirus, and hepatitis C virus, all positive-strand RNA viruses, utilize the maturation of a

251 and SIV(MAC) in addition to the negative and positive-strand RNA viruses vesicular stomatitis virus a

252 wn-regulate complementary RNA synthesis of a positive-strand RNA virus via an RNA-RNA interaction.

253 mato bushy stunt virus (TBSV), a small model positive-stranded RNA virus, we overexpressed 5,500 yeas

254 pendent RNA polymerase (RdRp), a hallmark of positive-strand RNA viruses, were identified in two cont

255 e coronavirus 2 (SARS-CoV-2) is an enveloped positive stranded RNA virus which has caused the recent

256 The Hepatitis C virus is a positive-stranded RNA virus which is the causal agent fo

257 Alphaviruses are emerging positive-stranded RNA viruses which replicate and transc

258 nderstanding the mechanism of replication of positive-strand RNA viruses, which are major pathogens o

259 Replication of positive-stranded RNA viruses, which are major pathogens

260 Brome mosaic virus (BMV) is a model positive-strand RNA virus whose replication has been stu

261 Brome mosaic virus (BMV) is a representative positive-strand RNA virus whose RNA replication, gene ex

262 Hepatitis C virus (HCV) is a positive strand RNA virus with a narrow host and tissue

263 alphanodavirus flock house virus (FHV) is a positive-strand RNA virus with one of the smallest known

264 TRV is a bipartite, positive-strand RNA virus with the TRV1 and TRV2 genomes

265 Coronaviruses are positive-strand RNA viruses with an unusually large geno

266 is likely relevant for other m(6)A-modified positive-strand RNA viruses with cytoplasmic life cycles

267 dicted RNA secondary formation in genomes of positive-stranded RNA viruses with their in vivo fitness

268 Hepatitis C virus (HCV) is a positive-strand RNA virus within the Flaviviridae family

269 Positive-strand RNA viruses within the Picornaviridae fa

270 of important human infections are caused by positive-strand RNA viruses, yet almost none can be trea