ライフサイエンスコーパス: postnatally

1 l mice and it is critical for their survival postnatally.

2 xpressed in mouse prostate and then silenced postnatally.

3 sent in the mature retina, are most abundant postnatally.

4 degeneration, necrosis and fibrotic change, postnatally.

5 estricted to CPN of the somatosensory cortex postnatally.

6 dominantly in CD90-positive lung fibroblasts postnatally.

7 h the most dramatic induction occurring 2 wk postnatally.

8 ocess initiating in the fetus and continuing postnatally.

9 ration, but YAP's mitogenic potency declines postnatally.

10 nadir platelet counts occurred up to 6 days postnatally.

11 cialized until target organogenesis occurred postnatally.

12 d by inducible inactivation of the Pkd1 gene postnatally.

13 differential abilities for continuous growth postnatally.

14 elopment with most growth variance occurring postnatally.

15 established in embryogenesis, and persisted postnatally.

16 in regulating intestinal health and survival postnatally.

17 MAFB transactivation during development and postnatally.

18 gely quiescent until they become reactivated postnatally.

19 ring development and subtle skeletal defects postnatally.

20 eart development, but is normally suppressed postnatally.

21 form-specific roles exist in these processes postnatally.

22 gical homeostasis of endoderm-derived organs postnatally.

23 dividual survived for more than three months postnatally.

24 with severity and with higher blood pressure postnatally.

25 om lymphocytes and hair follicles in infants postnatally.

26 intenance of sympathetic cardiac innervation postnatally.

27 C) lineage in utero and continues developing postnatally.

28 amic neuroepithelium, both embryonically and postnatally.

29 the final stage of lung development, occurs postnatally.

30 t birth, and at 6, 12, 24, 36, and 48 months postnatally.

31 s contributing to clonal evolution, pre- and postnatally.

32 tally, but inhibits epithelial proliferation postnatally.

33 d that much of this population was generated postnatally.

34 at birth and significant development occurs postnatally.

35 e establishment of dentate neural stem cells postnatally.

36 outcome was survival of the baby to 28 days postnatally.

37 e maturation of adrenal glomerular structure postnatally.

38 ng corticospinal tract (CST), which develops postnatally.

39 hese neurons in mice either embryonically or postnatally.

40 only mild pancreatic defects, which resolved postnatally.

41 the gene was deleted from excitatory neurons postnatally.

42 e amygdala is not fully mature for some time postnatally.

43 ng replication of viruses are only inhibited postnatally.

44 A neurons from rat pups younger than 15 days postnatally.

45 a is not fully mature for an extended period postnatally.

46 nesis during development and bone remodeling postnatally.

47 hylation prenatally to increased methylation postnatally.

48 elage follicles and lack vibrissae follicles postnatally.

49 rgical methods used to correct cleft defects postnatally.

50 system, but its expression is downregulated postnatally.

51 ment and acquire their final characteristics postnatally.

52 inhibition remains strong as the mice mature postnatally.

53 tions and then become selected or deselected postnatally.

54 herwise disrupted synaptic pruning occurring postnatally.

55 lls by 6 months after removing Mst1 and Mst2 postnatally.

56 arkers, but proliferative responses declined postnatally.

57 s had modest reduction in glomerular numbers postnatally.

58 (IUGR) have lower muscle mass that persists postnatally.

59 ently reduced at 2 but recovered at 12 weeks postnatally.

60 est during early development, and decreasing postnatally.

61 ntra-columnar segments as they become active postnatally.

62 ed in ten cases, of which all were confirmed postnatally.

63 Lymphocyte counts increased postnatally.

64 phenotypes were then validated and reported postnatally.

65 ne regulation and islet beta-cell maturation postnatally.

66 t affected Pdx1 expression embryonically and postnatally.

67 ells during development and down regulate it postnatally.

68 hile in the cerebellum it was also expressed postnatally.

69 ailed to establish alpha- and beta-cell mass postnatally.

70 the worsening of the microcephaly phenotype postnatally.

71 AID treatment for PDA initiated 2 to 28 days postnatally.

72 and epicardial zones of the ventricular wall postnatally.

73 or during labor/delivery and infant receipt postnatally.

74 islet vascularization during development and postnatally; (3) angiopoietin-Tie2 signaling in endothel

75 ough some cortical segments are active early postnatally, a functional sensory-motor control relies o

76 and the transferrin receptor 1 (Tfr1), were postnatally ablated specifically in SCs.

77 s) differentiate during fetal life, but only postnatally acquire the capacity for glucose-stimulated

78 Postnatally acquired cytomegalovirus (CMV) is typically

79 Postnatally acquired cytomegalovirus (pCMV) infection th

80 n the context of congenital toxoplasmosis or postnatally acquired disease in immunocompromised patien

81 asmosis, as a result of either congenital or postnatally acquired infections.

82 Postnatally acquired mutations then drive clonal evoluti

83 The clinical findings among children with postnatally acquired Zika virus disease are not well cha

84 odest but important level of protection from postnatally acquired ZIKV for several months after birth

85 Moreover, the impact of postnatally acquired, osteoblast-specific insulin defici

86 age caused by in utero exposure can reappear postnatally after an immune challenge.

87 Postnatally, all female offspring were maintained in nor

88 eported less alcohol consumption and smoking postnatally, all independent influences on growth at 6 m

89 r homeostasis due to minimal CLN3 expression postnatally, although this had not yet been demonstrated

90 ral development in Down syndrome (DS) occurs postnatally, an early opportunity exists to intervene an

91 nockout mice, RGL stem cells lose quiescence postnatally and enter into a high-proliferation regime t

92 evelopment, mice globally lacking CGI-58 die postnatally and exhibit a severe epidermal permeability

93 Mkx(-/-) mice survive postnatally and exhibit a unique wavy-tail phenotype.

94 Fate-mapping showed that LepR(+) cells arose postnatally and gave rise to most bone and adipocytes fo

95 ive process which is beneficial to the fetus postnatally and has the potential to identify normal ver

96 of MBP and deficient myelination were found postnatally and in adult R6/2 mouse model of HD.

97 nt mice show gradual loss of MAdCAM-1 in PPs postnatally and increased levels of mRNA for peripheral

98 In many vertebrates, neurogenesis continues postnatally and into adulthood in this region.

99 In humans, it grows sixfold postnatally and is a site of paediatric gliomas; however

100 In the mouse, septation occurs postnatally and is thought to require the alveolar myofi

101 TAM receptors are up-regulated postnatally and maintained at high levels in adults.

102 ram for hair cells generated and regenerated postnatally and may have broad implications for inner ea

103 Both arise postnatally and one is neither glycinergic nor GABAergic

104 gh its role in diverse cell types, including postnatally and prenatally generated neurons.

105 f serotonin is necessary to inhibit appetite postnatally and provide a proof of principle that select

106 diet, drugs, and stress both prenatally and postnatally and that these exogenous factors could also

107 igmented ciliary epithelial cells diminished postnatally and there was a concomitant increase in Fbn1

108 e FoxG1 continues to be expressed in neurons postnatally and through adulthood, its role in fully dif

109 KCC2b expression increased postnatally and was widely expressed in adult brain.

110 ld pairs prenatally, 5593 mother-child pairs postnatally, and 3009 father-child pairs).

111 dendroglia; the latter expand 10- to 18-fold postnatally, and are derived mostly from the parenchyma.

112 pproach to inducibly perturb neuron activity postnatally, and ask if Egr2-neurons control respiration

113 (Myom2), encoding M-protein, is upregulated postnatally, and based on this, we targeted TagRFP to th

114 ly that is GPI-linked, expressed principally postnatally, and enriched in sensory cortex.

115 munity, exposure to pathogens prenatally and postnatally, and findings of antibrain antibodies is com

116 ancy, in mothers and their partners at 47 mo postnatally, and in children at 10 y (n = 5717 mother-ch

117 ther-infant dyads, maternal hair was sampled postnatally, and infants underwent magnetic resonance im

118 specifically ablated from Pv(+) interneurons postnatally, and investigated the consequences of such a

119 t5a expression in hippocampal neurons begins postnatally, and its deletion attenuated CaMKII and Rac1

120 ive management note that some CLMs disappear postnatally, and that the long-term complication rate fo

121 Other postnatally appearing anti-carbohydrate antibodies are l

122 We show here that meningeal LVs develop postnatally, appearing first around the foramina in the

123 out life; however, current models posit that postnatally arising long-lived adult MSCs replace transi

124 indicates that these gene products function postnatally as a barrier to cellular transdifferentiatio

125 CD) and beta-thalassemia, become symptomatic postnatally as fetal gamma-globin expression from two pa

126 In humans, they persist postnatally as part of a network, with evidence supporti

127 high levels of PRDM6, which rapidly declined postnatally as the number of VSMCs necessary for ductus

128 Postnatally, associations between maternal depression an

129 ring embryonic development and is maintained postnatally at arterial branch sites.

130 nique: the final stages of development occur postnatally at puberty under the influence of hormonal c

131 Pdyn and Gal Although these mutants survive postnatally, at ~3-5 wk they elicit a severe scratching

132 ese with adult rats spinal transected 5 days postnatally, before most motor experience, using only ra

133 sient germinal compartment that produces all postnatally born GABAergic inhibitory interneurons and a

134 ally and selectively knockout notch 1 in the postnatally born immature neurons in the hippocampus dec

135 Conditional overexpression of NICD in the postnatally born immature neurons in the hippocampus inc

136 signaling cascade determining the number of postnatally born inhibitory interneurons in odor-activat

137 and dysregulation of Notch signaling in the postnatally born neurons disrupts their development and

138 d in upregulation of lung cell proliferation postnatally but had opposing effects following hyperoxia

139 plantation, some mice were treated with ACK2 postnatally, but the increase in engraftment was lower t

140 that astrocytes induce this critical barrier postnatally, but the timing of BBB formation has been co

141 phenotype associated with DS may be rescued postnatally by targeting trisomic Dyrk1a.

142 We developed mice in which COX-2 was deleted postnatally, bypassing cardiorenal defects exhibited by

143 Postnatally, c-Jun-deficient mice show a range of joint

144 Low expressers (<1%, n = 3) were postnatally challenged with 2 x 10(11) vg/kg AAV5 result

145 PFC-to-DRN circuits develop postnatally, coinciding with the period of PFC Slc6a4/SE

146 beta was up-regulated in the small intestine postnatally, concordant with a switch to Mypt1 E23 splic

147 eralized graded fibrocartilage that develops postnatally, concurrent with epiphyseal mineralization.

148 istent (> 14 years) preleukemic clone, which postnatally converts to ALL after the acquisition of nec

149 Persistence of these T(regs) postnatally could modify a child's susceptibility to mal

150 xt of presenilin loss, we used a mouse model postnatally deficient for PS (PS cDKO) and expressing wi

151 mouse in which the L-VOCC isoform Cav1.2 was postnatally deleted in NG2-positive OPCs.

152 itional KO mice in which these proteins were postnatally deleted in Sox10-positive SCs.

153 To examine this possibility, we postnatally deleted Tsc1 in vivo in a subset of hippocam

154 e, p27CKO leads to a significant addition of postnatally derived HCs that express characteristic syna

155 In postnatally derived hippocampal culture cells of C57BL/6

156 e the hypophosphatemic rickets animal model, postnatally developed severe periodontal defects.

157 tanding of OTR expression remains limited in postnatally developing brains.

158 P) within the external germinal layer of the postnatally developing cerebellum.

159 als, we show that nanoparticle deposition in postnatally developing lungs peaks at the end of bulk al

160 ce, including lethality, if MeCP2 is removed postnatally during the developmental stage that coincide

161 BMPR1 signaling controls dendrite complexity postnatally during the major dendritic growth period of

162 ough En1 expression in 5-HT neurons persists postnatally, En2 expression is extinguished by embryonic

163 ell fate, while in trimester three and early postnatally (Epoch-2) another set (the majority being br

164 he majority of infants do not contract HIV-1 postnatally, even in the absence of maternal antiretrovi

165 Remarkably, Mek1/2-deleted mice surviving postnatally exhibit cortices almost devoid of astrocytes

166 Rats of the inbred BD strains postnatally exposed to the carcinogen N-ethyl-N-nitrosou

167 At 8 wk old, the offspring prenatally and postnatally exposed to unfiltered air were significantly

168 and Pit2 in skeletal muscle (sm), using the postnatally expressed human skeletal actin-cre.

169 tional factors, including Zic1 and Zic2, are postnatally expressed in the dorsal stem cell compartmen

170 Postnatally, expression is limited to developing bone an

171 M ligand, which was constitutively expressed postnatally, expression of GAS6 initiated only 3-4 wk af

172 adaptation, demonstrating adaptation occurs postnatally, following mechanical loading, and is almost

173 nd discuss how PN classes may be maintained, postnatally, for the life of the organism.

174 f hair cells and supporting cells is derived postnatally from Axin2-expressing TBCs.

175 embryonically from CX3CR1(+) precursors and postnatally from bone marrow-derived monocytes that colo

176 we show that the MHC II(+) macrophages arise postnatally from CCR2-dependent precursors that resemble

177 letal or extraskeletal problems will develop postnatally from exposure to vitamin D deficiency in ute

178 tion of plasma PC in these infants increased postnatally from median values of 481 (IQR: 387-798) uM

179 d that they may functionally distinguish MNs postnatally from other spinal neurons.

180 Whereas Ripk1(-/-) mice died postnatally from systemic inflammation, Ripk1(D325A/D325

181 Here, we show that in vivo postnatally generated and regenerated hair cells in the

182 mouse model to selectively delete PTEN from postnatally generated DGCs.

183 Although the vast majority of these postnatally generated interneurons are inhibitory, a sub

184 witch from tangential to radial migration of postnatally generated neuroblasts in the olfactory bulb.

185 However, neither when new postnatally generated OSNs first form synapses nor wheth

186 atum appears restricted to interneurons, and postnatally generated striatal neurons are preferentiall

187 neurons, we investigated whether the fate of postnatally generated SVZ neurons can be altered.

188 We compared postnatally generated wild-type and Pten knockout granul

189 ow that the murine pons quadruples in volume postnatally; growth is fastest during postnatal days 0-4

190 NT-3 and CNTF, which normally increase postnatally, had significantly reduced expression in the

191 ying a relatively large infant both pre- and postnatally has important ramifications for birthing str

192 e lacking myosin IIIb and losing myosin IIIa postnatally have normal hearing.

193 ational weeks and cases of preeclampsia were postnatally identified from registers.

194 Ahr(-/-) mice also lacked postnatally 'imprinted' cryptopatches and isolated lymph

195 on is extinguished perinatally but reemerges postnatally in a subpopulation of large-diameter GG neur

196 t low-dose rapamycin given prenatally and/or postnatally in a well-established neuroglial (Tsc2-hGFAP

197 ntial roles during embryonic development and postnatally in adult tissues; misregulated signaling res

198 pment in mice, but the restricted expression postnatally in bone, ligaments and tendons correlates wi

199 Although the RST is present postnatally in cats, nothing is known about when rubrosp

200 We found that Set-beta was upregulated postnatally in CNS neurons, and was primarily localized

201 Formerly weight gain postnatally in combination with insulin-like growth fact

202 rmed during development that were not pruned postnatally in deaf cats.

203 We knocked out Ctcf postnatally in glutamatergic forebrain neurons under the

204 ich histone deacetylase 3 (Hdac3) is deleted postnatally in heart and skeletal muscle.

205 ic mice, CELF splicing activity is inhibited postnatally in heart muscle via expression of a nuclear

206 P4 in our mouse model of IPS, as it might do postnatally in IPS patients.

207 n utero, if predicted prenatally, or rescued postnatally in less severe cases.

208 C junctions that increases more than sixfold postnatally in mice.

209 to the Igf2 promoter all decreased with age postnatally in multiple mouse organs.

210 ent of RhoA abundance, which was unperturbed postnatally in our mutants.

211 even though there is a rapid loss of oocytes postnatally in ovaries with combined loss of Sohlh1 and

212 We inactivated Pdgfra postnatally in secondary crest myofibroblasts (SCMF), a

213 study, we show that beige adipocytes formed postnatally in subcutaneous inguinal white adipose tissu

214 ngs indicate that a stem cell niche develops postnatally in the epiphyseal growth plate, which provid

215 ed in-depth during fetal development but not postnatally in the epiphysis.

216 bunit of the NMDA receptor was overexpressed postnatally in the excitatory neurons of the forebrain a

217 Whilst Dcc is expressed postnatally in the eye, its function remains unknown as

218 molecular and Purkinje cell layer, but only postnatally in the granule cell layer and the dentate nu

219 Neurogenesis persists postnatally in the human subventricular zone (SVZ) where

220 anching morphogenesis during development and postnatally in the mammary gland.

221 These events occur postnatally in the mouse.

222 er, whether the epicardium has similar roles postnatally in the normal and injured heart remains enig

223 ritubular macrophages are exclusively seeded postnatally in the prepuberty period from bone marrow (B

224 report that subluminal Misr2+ cells persist postnatally in the uterus of rodents, but recede by week

225 PQQ treatment given pre- and postnatally in WD-fed offspring had no effect on weight

226 ately by an antagonist twitch-that developed postnatally in wild-types/heterozygotes, but not in knoc

227 ptor in tendons caused severe tendon defects postnatally, including decreased tendon thickness, indic

228 our study lacks an important comparison with postnatally infected infants born to naive dams, our dat

229 a nonhuman primate model showed that infants postnatally infected with Zika virus (ZIKV) were acutely

230 perfectly conserved amino acids incorporated postnatally into TBC1D24 protein due to a micro-exon uti

231 valvuloplasty and achieved a BV circulation postnatally is encouraging.

232 ofile of RdRP mice is mostly triggered early postnatally, is maintained through adulthood, and requir

233 east-feeding mother, that is, prenatally and postnatally, is safe and effective in reducing the risk

234 ell population, retained in the mouse cortex postnatally, is virtually extinguished at puberty.

235 Early postnatally, layer-2 pyramidal but not stellate-cells co

236 Mice ubiquitously depleted of PIEZO2 are postnatally lethal.

237 oupled; however, whether hair cells emerging postnatally mature similarly is unknown.

238 nd that prioritizing less advantaged mothers postnatally may be most effective.

239 predictive value, and tests acquired 24-48 h postnatally may provide reassurance for safe discontinua

240 Postnatally, mice were evaluated for their resistance to

241 Postnatally, mutant mice developed signs of renal diseas

242 te proliferation but it has not been studied postnatally or in fully mature adult cardiomyocytes.

243 CI, 1.06-1.79; P value for trend = .03) and postnatally (OR, 1.53; 95% CI, 1.16-2.01; P value for tr

244 Starting postnatally, OSN differentiation is decreased and progen

245 associated with offspring depression, while postnatally, paternal depression showed a similar patter

246 kdown of BDNF expression in supporting cells postnatally phenocopies the loss of erbB signaling.

247 tives of every superfamily in which a VNO is postnatally present.

248 tin, a product of the SOST gene, is produced postnatally primarily by osteocytes and is a negative re

249 Conditional deletion of VMAT2 in astrocytes postnatally produces loss of PFC DA homeostasis, leading

250 n the capacity of neurogenesis, and in fact, postnatally proliferating cells expressed Tbx1.

251 ng that a previously unknown genetic program postnatally promotes the acquisition of final subtype-sp

252 ted hypertension, and we proposed a role for postnatally raised leptin in its etiology.

253 The aberrant phenotype persisted postnatally regardless of the adult vitamin A status and

254 The expression of CRIg in TRMs was postnatally regulated by gut microbial signals and metab

255 developed proteinuria and glomerulosclerosis postnatally, resembling FSGS.

256 -cell population and that MafB expression is postnatally restricted in mouse beta-cells by de novo DN

257 tein expression was enriched in regions that postnatally retain the capacity of neurogenesis, and in

258 idual indicated that somatic reversions were postnatally selected.

259 the mouse retina, where angiogenesis occurs postnatally, somatic deletion in RMCs of the Wnt ligand

260 s appear to overshoot into type II territory postnatally, specificity may also depend on elimination

261 immune and IFN signaling are only activated postnatally, suggesting constrained fetal responsiveness

262 ooth muscle cells forms in the embryo and is postnatally sustained at arterial branch sites.

263 rs required for embryonic tissue development postnatally take on distinct roles through interaction w

264 ally distinct concentric layers that develop postnatally, the outer zona glomerulosa (zG) and the inn

265 Postnatally, the tumor either involutes quickly (i.e., r

266 Postnatally, these cells rapidly respond to commensal an

267 Postnatally, these compound mutant mice develop a unique

268 Postnatally, these mice exhibited a normal initiation of

269 s that half of the 16p11.2 deletion mice die postnatally; those that survive to adulthood are healthy

270 Phase 2 occurs postnatally through adult stages with bone marrow produc

271 Neural stem and precursor cells persist postnatally throughout adulthood and are capable of resp

272 ig SMN1, SMN was knocked down in motoneurons postnatally to SMA levels.

273 o-transmission is reduced in animals exposed postnatally to SSRIs.

274 Secretory pancreatic acinar cells mature postnatally to synthesize large amounts of protein, pola

275 on the opposite side of the bulb and refine postnatally to their adult precision by 7 weeks of age i

276 ic SIV infections, rarely transmit the virus postnatally to their infants, and exhibit anatomically c

277 do not typically progress to AIDS and rarely postnatally transmit virus to their infants, despite hig

278 antibody responses of clade C HIV-1-infected postnatally transmitting and nontransmitting mothers in

279 combined therapy did not perform as well as postnatally-treated animals in learning and memory tasks

280 ol) or SS throughout the gestation period or postnatally up to 10 weeks.

281 rmine which type(s) of hair cells are formed postnatally, we fate-mapped neonatal supporting cells by

282 To demonstrate that this pathway works postnatally, we used a conditional, brainstem-specific m

283 irst year, second year, or first three years postnatally were submitted to data-driven modeling to di

284 In the PNS, myelination occurs postnatally when Schwann cells (SCs) contact axons.

285 ingrowth of nerve fibers into islets occurs postnatally, when islet vascularization is already compl

286 Gonadal fat develops postnatally, whereas subcutaneous fat develops between e

287 is expressed thousands of times in utero and postnatally, whereas the latter is elicited de novo by p

288 ith progressive proteinuria as early as 2 wk postnatally, which coincided with loss of nephrin expres

289 us hippocampal neurons are myelinated mainly postnatally, which is important for the proper function

290 IUGR) have reduced muscle mass that persists postnatally, which may contribute to their increased ris

291 r B (MAFB) to be present in human beta-cells postnatally, while its expression is restricted to embry

292 ncy and maternal and paternal dietary intake postnatally with child dietary intake and adiposity.

293 These fibroblasts were labeled postnatally with green fluorescent protein using mice ex

294 and pups were challenged at different times postnatally with lethal doses of HSV-1 or HSV-2.

295 cells (Adam10/Adam17DeltaEC), which survived postnatally with organ-specific vascular defects, resemb

296 Homozygous Cdk10-knockout mice died postnatally with severe growth retardation, skeletal def

297 ibition, we treated Lama2(Dy-w)Bax(-/-) mice postnatally with systemic recombinant human IGF-1 (IPLEX

298 these modulated immune responses to persist postnatally, with a subsequent increase in a child's sus

299 capacity at birth but this capacity is lost postnatally, with subsequent organ growth occurring thro

300 zygous knockout mice lacking this enzyme die postnatally within 24 h, whereas PIPKIgamma(+/-) sibling