ライフサイエンスコーパス: potassium channel

1 ired, the human ether-a-go-go-related (hERG) potassium channel.

2 hannel (also known as K(2P)18.1)] background potassium channel.

3 onal expression of the renal outer medullary potassium channel.

4 g of a G-protein-coupled inwardly rectifying potassium channel.

5 ng to identify genetic variants of the KCNQ1 potassium channel.

6 9 is also moderately active against the hERG potassium channel.

7 ceptor tyrosine kinase FGFR1 and cardiac IKS potassium channel.

8 H) neurons through opening the ATP-sensitive potassium channel.

9 SMC electrical activity by inhibiting SLO2.1 potassium channels.

10 lter, has been recently proposed for several potassium channels.

11 erologously expressed Kv4.3, Kv1.5 and Kv2.1 potassium channels.

12 rives the production of activity-suppressing potassium channels.

13 f the properties of voltage-gated sodium and potassium channels.

14 pening of small-conductance Ca(2+)-activated potassium channels.

15 effector molecules including lipid-regulated potassium channels.

16 ctivation and the subsequent closure of KCNQ potassium channels.

17 ough the activation of voltage-gated KCNQ2-5 potassium channels.

18 afferent input impedance by closing calyceal potassium channels.

19 o activate at a rate similar to conventional potassium channels.

20 acterial MscL channel and certain eukaryotic potassium channels.

21 polarization caused by stretch activation of potassium channels.

22 derivatives are able to block voltage-gated potassium channels.

23 ivity of the binding sites along the pore of potassium channels.

24 d 2) reduced activation of voltage-dependent potassium channels.

25 and more efficiently recruiting subthreshold potassium channels.

26 h the activation of associated calcium-gated potassium channels.

27 esence or absence of a few large-conductance potassium channels.

28 pendent processes, such as calcium-activated potassium channels.

29 larization-activated cyclic-nucleotide-gated potassium channel 1 (HCN1) pacemakers were required for

30 odes the small conductance calcium-activated potassium channel 2 (SK2).

31 The TWIK-related acid-sensitive potassium channel 3 (TASK-3; KCNK9) tandem pore potassiu

32 ively activated the vascular-expressed KCNQ5 potassium channel, a feature lacking in the modern synth

33 The selectivity filter in potassium channels, a main component of the ion permeati

34 Slo2 channels are large-conductance potassium channels abundantly expressed in the nervous s

35 assium (BK) channels and Kv3.3 voltage-gated potassium channels accompanies the inability of Purkinje

36 nnels (VGCCs) and negatively regulated by BK potassium channels activated by Ca(2+) influx through L-

37 Cilantro leaf harbors a potent potassium channel-activating anticonvulsant.

38 Finally, we show theoretically that reduced potassium channel activation selectively increases gain

39 an important regulator of voltage-gated hERG potassium channel activity and therefore cardiac repolar

40 porter SGLT1, or by closure of ATP-sensitive potassium channels after glucose metabolism.

41 beta cells, including the T2DM-linked KCNQ1 potassium channel alpha subunit.

42 mouse Kcne2 reduced pulmonary expression of potassium channel alpha subunits Kcnq1 and Kcnb1 but did

43 RPV1, TRPA1 and P2X2 increased, and Kv1.4, a potassium channel alpha-subunit that can form A-type pot

44 ductance Ca2+- and voltage-activated K+ (BK) potassium channel alpha-subunit, and pathogenic gain-of-

45 ) channels composed of a pore-forming Kir6.2 potassium channel and a regulatory ABC transporter sulfo

46 tor-mediated inhibition of a two-pore domain potassium channel and A1 receptor-mediated opening of a

47 ular assemblies, including the ATP-sensitive potassium channel and the peptide-loading complex, but a

48 ignatures of infection, such as induction of potassium channels and amino acid transporters, derepres

49 PV+ cells by regulating the localization of potassium channels and AMPA receptors, respectively.

50 sensitivity to ATP, downregulation of Kir4.1 potassium channels and increased cytokine synthesis and

51 dopts the Kunitz fold known to mostly act on potassium channels and serine proteases.

52 was dependent on functional big conductance potassium channels and was absent in big conductance pot

53 This also depends on slow delayed-rectifier potassium channels, and preferred theta ranges shift whe

54 ion of the NKCC1 inhibitor bumetanide or the potassium channel antagonist Tetraethyl ammonium had no

55 EAG-like (ELK) voltage-gated potassium channels are abundantly expressed in the brain

56 KCNQ2 potassium channels are critical for normal brain functio

57 ated human ether-a-go-go-related gene (hERG) potassium channels are critical for the repolarization o

58 ts in the presynaptic terminals, where Kv1.2 potassium channels are downregulated.

59 Kv11.1 potassium channels are essential for heart repolarizatio

60 Kv3.1 and Kv3.2 voltage-gated potassium channels are expressed on parvalbumin-positive

61 POINTS: Intracellular Na(+) -activated Slo2 potassium channels are in a closed state under normal ph

62 K2P potassium channels are known to be modulated by volatile

63 Potassium channels are known to be strategically localiz

64 Potassium channels are opened by ligands and/or membrane

65 Potassium channels are presumed to have two allosterical

66 These findings highlight the KCNQ-type potassium channel as a promising target for future drug

67 iated optical control of inwardly rectifying potassium channels, as well as adenylyl cyclase.

68 Decreased levels of functional K(v)11.1 potassium channel at the plasma membrane of cardiomyocyt

69 The KCNE2 potassium channel beta subunit is required for normal lu

70 ardiac-specific germline deletion in mice of potassium channel beta subunit-encoding Kcne2 (Kcne2(CS-

71 TIONALE: Large-conductance calcium-activated potassium channels (BK) are composed of pore-forming BKa

72 action of a classical CaV-like channel and a potassium channel, BK (Slo1), whereas the second module

73 y by chronic treatment with the FDA-approved potassium channel blocker 4-aminopyridine (4-AP) improve

74 The potassium channel blocker 4-aminopyridine reliably induc

75 s and the isolated guinea pig brain with the potassium channel blocker 4-aminopyridine.

76 KCl and the potassium channel blocker tolbutamide also stimulated pr

77 sing tetraethylammonium (TEA), a presynaptic potassium channel blocker, we show that the apparent red

78 ine (4AP, molecular weight 94.1146 g/mol), a potassium-channel blocker as a growth factor alternative

79 Applying specific potassium channel blockers diminished the hyperexcitabil

80 for the large conductance calcium-activated potassium channel brings new thinking about regulation o

81 her sensory modalities express many types of potassium channels, but how they combine to control firi

82 ecular gating mechanism in calcium-activated potassium channels by obtaining structures of the MthK c

83 pharmacological targeting of a mitochondrial potassium channel can lead to ROS-mediated selective apo

84 Potassium channels can become nonconducting via inactiva

85 rns and understanding the role of particular potassium channels can help to guide new pharmacological

86 6.3%): 3 (2.7%) had TPO-Ab and voltage-gated potassium channel complex (VGKCc) Ab, 2 (1.8%) had GAD65

87 ntibodies to components of the voltage-gated potassium channel complex (VGKCC-Ab-LE) often leads to h

88 sting the formation of pulmonary Kcnq1-Kcne2 potassium channel complexes.

89 independently of TIM in Drosophila to alter potassium channel conductance in arousal neurons after l

90 scovered that yeast cells lacking endogenous potassium channels could be rescued by WT ROMK but not b

91 (G(i/o)) of adenylyl cyclase, stimulation of potassium channel currents (G(i)), and activation of pho

92 e block of stretch-sensitive ATP-inactivated potassium channels curtailed VF occurrence in a porcine

93 Conversely, high sodium intake inhibited the potassium channel, decreased basolateral K(+) currents,

94 (human Ether-a'-go-go-Related Gene) cardiac potassium channel delays cardiac repolarization and can

95 d potassium channel sodium-activated (Slack) potassium channels, demonstrating macrocomplexing with N

96 ion, 5F8 is clearly among the best synthetic potassium channels developed over the past decades.

97 nd interventions targeted towards correcting potassium channel dysfunction in ataxia need to be tailo

98 sphatidic acid at lipid-binding sites within potassium channels [e.g., TWIK-related K(+) channel type

99 r-mediated pathway that impinges on specific potassium channel effectors.

100 For improved safety, this engineered potassium channel (EKC) gene was packaged into a noninte

101 us exhibited reduced total expression of the potassium channel ether-a-go-go-related gene (rbERG).

102 Sodium and potassium channels exhibit a one-dimensional periodicity

103 The slow spontaneous inactivation of potassium channels exhibits classic signatures of transm

104 BK, Slo1, MaxiK, KCNMA1) is the predominant potassium channel expressed at the plasma membrane of rh

105 l action potential duration were reduced and potassium channel expression (Kv1.5) and current (I(Kur)

106 TASK channels belong to the two-pore domain potassium channel family and are modulated by extracellu

107 Subsequently, sigma1 binds to Kv1.2 potassium channels, followed by accumulation of Kv1.2 in

108 ng novel pharmaceutical target-the KCNQ-type potassium channel-for the treatment of depressive disord

109 Voltage-gated potassium channels formed by KCNQ2 and KCNQ3 are essenti

110 hough this is the case for calcium-dependent potassium channels found at the cell body, we show here

111 MthK, a two transmembrane calcium-activated potassium channel from thermophilic archaebacteria.

112 The roles of potassium channels from the Shaker family in stomatal mo

113 ting tumor viability and invasion, including potassium channel function and EPH receptor signaling.

114 assium channel 3 (TASK-3; KCNK9) tandem pore potassium channel function is activated by halogenated a

115 intrinsic excitability via the regulation of potassium channel function.

116 The canonical mechanistic model explaining potassium channel gating is of a conformational change t

117 technology to increase the expression of the potassium channel gene Kcna1 (encoding Kv1.1) in mouse h

118 t with increased expression of voltage-gated potassium channel gene Kcna1 and decreased expression of

119 The potassium channel gene KCNA1 was mutated to bypass post-

120 Among those, we found potassium channel genes KCNA4 and KCNIP4, involved in el

121 G-protein-gated inward rectifying potassium channels (GIRKs) require G(betagamma) subunits

122 luding G-protein-coupled inwardly rectifying potassium channels (GIRKs)(1,2).

123 d expression of the 3.1 isoform of the KCNH2 potassium channel has been associated with cognitive dys

124 In general, potassium channels have an intramembrane vestibule with

125 C-type inactivation in potassium channels helps fine-tune long-term channel act

126 toxicity related to anti-human ether-a-go-go potassium channel (hERG) activity of the first-generatio

127 The human ether-a-go-go-related potassium channel (hERG, Kv11.1) is a voltage-dependent

128 of the rapidly activating delayed rectifier potassium channel (I(Kr)).

129 -positive specimens had higher voltage-gated potassium channel-IgG immunoprecipitation values (0.33nm

130 e intermediate conductance calcium-activated potassium channel (IKCa) was termed SK4 because of the h

131 The cardiac potassium channel, IKr, and the adrenergic-sensitive car

132 to characterize the VSD derived from Shaker potassium channel in 1-palmitoyl-2-hydroxy-sn-glycero-3-

133 unrecognized role of the truncated KCNH2-3.1 potassium channel in mediating complement activation, wh

134 We detected a 40-pS and 20-pS potassium channel in the basolateral membrane of the DCT

135 The basolateral potassium channel in the distal convoluted tubule (DCT),

136 Knowing that downregulation of Kv1.2 potassium channel in the IN nerve terminals likely augme

137 ion, our results reveal a role for the KCNQ1 potassium channel in the regulation of human growth, and

138 ll body, we show here that calcium-dependent potassium channels in dendrites of cortical pyramidal ne

139 Potassium channels in parvalbumin-type models deactivate

140 reby demonstrating the involvement of A-type potassium channels in prolonging pauses evoked by GABAer

141 we analyzed the expression of voltage-gated potassium channels in rodent and primate brains using qP

142 regions and increased expression of specific potassium channels in the NAc may promote abstinence fro

143 gating model of selectivity filter-activated potassium channels, including pharmacologically relevant

144 leads to epigenetic repression of Kv1.1-type potassium channels, increased excitability, and impaired

145 The hERG potassium channel influences ventricular action potentia

146 euronal hyperexcitability, induced by M-type potassium channel inhibition, triggered intrinsic and sy

147 A dataset of 55 hERG potassium channel inhibitors collected from Kramer et al

148 the human ether-a-go-go-related gene (hERG) potassium channel interact.

149 hippocampal cultures and asked how distinct potassium channels interact in determining the basal spi

150 vitro and in vivo, binds epilepsy-associated potassium channel-interacting proteins including KCNAB2

151 di-AMP is known to directly regulate several potassium channels involved in osmolyte transport in spe

152 ty mediated by decreased inwardly rectifying potassium channel (IRK) function.

153 11.1 hERG (human ether-a-go-go related gene) potassium channel is a critical regulator of cardiomyocy

154 TRESK background potassium channel is a potential pharmacological target

155 The function of the voltage-gated KCNQ1 potassium channel is regulated by co-assembly with KCNE

156 In neurons, inactivation of both sodium and potassium channels is crucial for the generation of acti

157 -1) (K(2P)3.1) atrial-specific 2-pore domain potassium channels is enhanced, resulting in action pote

158 ariants in KCNB1, encoding the voltage-gated potassium channel K(V) 2.1, are associated with developm

159 P2X purinoceptor 7 (P2X7), the voltage-gated potassium channel K(V)1.3 and the voltage-gated sodium c

160 of transcripts encoding the sodium-activated potassium channels K(Na)1.1 (SLO2.2/Slack) and K(Na)1.2

161 fold, which selectively blocks voltage-gated potassium channels K(v)1.3.

162 The two-pore domain potassium channel (K(2P)-channel) THIK-1 has several pre

163 The ATP-sensitive potassium channel (K(ATP) channel) couples blood levels

164 rmore, we found that beta cell ATP-sensitive potassium channel (K(ATP)) channels are required for HDL

165 Two-pore-domain potassium channels (K(2P)) are the major determinants of

166 (4AP) is a specific blocker of voltage-gated potassium channels (K(V)1 family) clinically approved fo

167 Voltage-gated potassium channels (K(v)s) are gated by transmembrane vo

168 Voltage-dependent potassium channels (K(v)s) gate in response to changes i

169 ed to faster inactivation of a voltage-gated potassium channel, K(v)1.4.

170 roach, we discovered that a pair of two-pore potassium channel (K2P) subunits, largely dispensable ea

171 In contrast to other potassium channels, K2P channels use a selectivity filte

172 ABSTRACT: Sarcolemmal ATP-sensitive potassium channel (KATP channel) activation in isolated

173 Sarcolemmal ATP-sensitive potassium channels (KATP channels) in cardiac myocytes a

174 Large-conductance calcium-activated potassium channel (KCa1.1; BK, Slo1, MaxiK, KCNMA1) is t

175 n associated with this trait we identify the potassium channel, Kcnh8, as a sword development gene.

176 Either of 2 somatic mutations in the potassium channel KCNJ5 (G151R and L168R, hereafter refe

177 ification of deleterious genetic variants in potassium channels (KCNK3 and ABCC8) and transcription f

178 els, which include the Trp channel Trpm8 and potassium channel Kcnk9, that are potentially required f

179 genes, an increase of the calcium-activated potassium channel Kcnn2 in the motor cortex correlated w

180 tassium binding affinity of the prototypical potassium channel KcsA in the context of C-type inactiva

181 Inward rectifier potassium channel (Kir) Kir2.2 has multiple interactions

182 occurs via activation of inwardly rectifying potassium channels (KIR ), and synthesis of nitric oxide

183 ainate receptor GluR6/7 and inward rectifier potassium channel Kir2.1, closely associated with SAP102

184 ough co-expression of an inwardly rectifying potassium channel (Kir2.1).

185 reduced function of the inwardly rectifying potassium channel, Kir2.

186 The potassium channel Kir4.1 forms the Kir4.1/Kir5.1 heterot

187 Here, we tested the hypothesis that the potassium channel Kir4.1 is the potassium sensor of DCT

188 Whether the basolateral, inwardly rectifying potassium channel Kir4.1/Kir5.1 (a heterotetramer of Kir

189 le (DCT), comprising the inwardly rectifying potassium channel Kir4.1/Kir5.1 heterotetramer, plays a

190 KCNJ13 gene encodes the inwardly rectifying potassium channel, Kir7.1.

191 m channels and was absent in big conductance potassium channels knockout mice.

192 conductance, calcium- and voltage-activated potassium channel, known as the BK channel, is one of th

193 Neuronal voltage-gated potassium channels (Kv) are critical regulators of elect

194 ng in transcripts encoding the voltage-gated potassium channel Kv1.1 converts an isoleucine to valine

195 The gene encoding the voltage-gated potassium channel Kv1.1, KCNA1, was codon optimized for

196 The potassium channel Kv1.3 is highly expressed in the mitoc

197 The voltage-dependent potassium channel Kv1.3 plays essential physiological fu

198 s treatable by blockade of the voltage-gated potassium channel Kv1.3.

199 The voltage-gated potassium channel Kv1.5 plays important roles in atrial

200 e Stichodactyla helianthus, which blocks the potassium channels Kv1.1 and Kv1.3 with pM affinity.

201 nnels at the node of Ranvier and Shaker-type potassium channel (Kv1.2) at the juxtaparanode.

202 assess the functions of select voltage-gated potassium channels (Kv1, Kv2, Kv3, and Kv4) in shaping a

203 ed by the reduction in the expression of the potassium channel Kv2.1 at the surface of motor neurons.

204 ia increased levels of oxidized, inactivated potassium channel Kv2.1, which undergoes disulfide bridg

205 lular localization and cellular level of the potassium channel Kv3.1 in cells.

206 may be related to the expression of the fast potassium channel Kv3.1b, which in rat interneurons is a

207 olecular mechanisms revealed that the A-type potassium channel Kv4.2 subunit is a molecular target of

208 iated inactivation of presynaptic Kv1-family potassium channels, leading to action potential broadeni

209 Suppression of m-type potassium channels (M-channels) has been found to contri

210 the human ether a go-go-related gene (hERG) potassium channel, many of which cause misfolding and de

211 subclasses of voltage- and/or calcium-gated potassium channels may provide an important approach to

212 Kv3 voltage-gated potassium channels mediate action potential (AP) repolar

213 d that a G-protein-coupled inward-rectifying potassium channel mediated regulation of dendritic plate

214 ow membrane resistance and inward-rectifying potassium channel-mediated current, and are extensively

215 of sodium channel blockers in patients with potassium channel-mediated long QT syndrome (ie, LQT1 an

216 wo-thirds of a small subset of patients with potassium channel-mediated LQT2.

217 Several different potassium channels modulate the activity of sleep-promot

218 Following the recent development of a potassium channel modulator, AUT1-an imidazolidinedione

219 h the increased activity of barium-sensitive potassium channels, most consistent with inwardly rectif

220 mulations, to study ion permeation through a potassium channel MthK, for various opening levels of bo

221 rome of myoclonus epilepsy and ataxia due to potassium channel mutation (MEAK), including cellular el

222 and calcium (Kcnma1, Kcnn1 and Kcnn2)-gated potassium channels observed in the NAc of nonaddicted ra

223 In addition, affinity toward the hERG potassium channel of compound 30 was significantly reduc

224 Voltage-gated potassium channels of the KCNQ (Kv7) subfamily are essen

225 Discovery of botanical KCNQ5-selective potassium channel openers may enable future targeted the

226 Two-pore domain (K2P) potassium channels perform essential roles in neuronal f

227 Slo2 potassium channels play important roles in neuronal func

228 red that TRESK, a calcium regulated two-pore potassium channel, plays a crucial role in this system.

229 We identified SLO2.1, a potassium channel previously unknown in uterine smooth m

230 the KCNT1 (Slack, K(Na)1.1) sodium-activated potassium channel produce severe epileptic encephalopath

231 ibutable to interdependence of voltage-gated potassium channel properties.

232 ine small conductance (SK) calcium-activated potassium channel protein levels.

233 vated calcium currents, and independently of potassium channel regulation, membrane potential changes

234 However, it is unknown how the potassium channel-repressed calcium signaling is transla

235 xpressed the intermediate-conductance KCa3.1 potassium channel, revealing a strong functional couplin

236 confirmed; thereafter, reduced levels of the potassium channel ROMK and kinases SGK1 and WNK1 were ob

237 Although potassium channels shape neuronal activity, their roles

238 that currents mediated by the voltage-gated potassium channels Shaw (Kv3) and Shal (Kv4) oscillate i

239 ther the BK channel SLO-1 or the Shaker type potassium channel SHK-1.

240 aspartate receptors and weakened by cAMP-PKA-potassium channel signaling in dendritic spines.

241 Three small conductance calcium-activated potassium channel (SK) subunits have been cloned and fou

242 Small conductance calcium-activated potassium channels (SK channels) are present in spines a

243 mpact of small conductance calcium-activated potassium channels (SK channels) on dendritic excitabili

244 on of the Ca(2+)-activated small conductance potassium channel, SK2, contributes to impairment of syn

245 1 bound to sequence like a calcium-activated potassium channel sodium-activated (Slack) potassium cha

246 Unlike potassium channels, sodium channel alpha-subunits are be

247 The voltage-gated potassium channel subfamily A member 3 (Kv1.3) dominantl

248 y contraction and relaxation associated with potassium channel subfamily K member 3 (KCNK3) dysfuncti

249 Loss of function mutations in KCNK3 (potassium channel subfamily K member 3) gene, which enco

250 Neuronal voltage-gated potassium channel subfamily Q (KCNQ) dysfunction can cau

251 ent of the potency of block of voltage-gated potassium channel subtype 11.1 (K(v)11.1) as a surrogate

252 nctional expression of the voltage-dependent potassium channel subunit Kv1.1 substantially contribute

253 ding protein parvalbumin (PV), and the Kv3.3 potassium channel subunit.

254 et al., Nature, 2019) found that one of the potassium channel subunits, Hyperkinetic, alters the fir

255 D afferents express KCNQ3, KCNQ4, and ERG1-3 potassium channel subunits.

256 The ability of NMDARs to regulate potassium channel surface expression and thus, beta-cell

257 3, the gene that encodes the two pore domain potassium channel TASK-1 (K2P3.1), has been identified a

258 is and the role of an atrial specific 2-pore potassium channel TASK-1 as a therapeutic target for atr

259 for a photochromic blocker of voltage-gated potassium channels, termed CAL, and a photochromic opene

260 y neurons and an ether-a-go-go (EAG)-related potassium channel that functions in these neurons as key

261 evealed the three-dimensional structure of a potassium channel that has a central role in regulating

262 flux and the intermediate-conductance KCa3.1 potassium channel that promotes an outward tail current

263 Kv11.1 (hERG) is a voltage-gated potassium channel that shows very slow ionic current act

264 lepsy gene Kcna1 encodes voltage-gated Kv1.1 potassium channels that act to dampen neuronal excitabil

265 Slack (KCNT1) gene encodes sodium-activated potassium channels that are abundantly expressed in the

266 We investigated the potassium channels that shape the reliability of signal

267 notyped for 12 genes for vascular signaling, potassium channels, the HTR1A(serotonin 5-HT1A receptor)

268 As for other potassium channels, there is a lack of selective blocker

269 tion is via blockade of axonal voltage gated potassium channels, thereby enhancing conduction in demy

270 The potassium channel THIK-1 is strongly expressed in the ce

271 s established using gap junctions and SLO BK potassium channels to repress a calcium-activated protei

272 n downstream recruitment of Ca(2+)-activated potassium channels to the plasma membrane.

273 maintenance of AWC asymmetry, couples SLO BK potassium channels to transactivation of sox-2 expressio

274 nistic insight into how NSY-7 couples SLO BK potassium channels to transactivation of sox-2 expressio

275 Here we report that the KCNE2 potassium channel transmembrane regulatory subunit is ex

276 an aberrant modulation of the mechano-gated potassium channel, TREK-1.

277 The two-pore potassium channel, TRESK has been implicated in nocicept

278 anism of regulation of the proton pump and a potassium channel, two essential elements in K(+) uptake

279 However, in several voltage-gated potassium channels, using specific S4-S5(L)-mimicking pe

280 nce imaging has linked chronic voltage-gated potassium channel (VGKC) complex antibody-mediated limbi

281 e extracellular domains of the voltage-gated potassium channel (VGKC) complex proteins, leucine-rich

282 ntigenic components within the voltage-gated potassium channel (VGKC) complex.

283 In voltage-gated potassium channels (VGKC), voltage sensors (VSD) endow v

284 rimental determination of the structure of a potassium channel VSD in the intermediate state has prev

285 l structure of the human KCNQ1 voltage-gated potassium channel VSD in the intermediate state.

286 rated that microglial Kv1.3, a voltage-gated potassium channel, was transcriptionally upregulated in

287 was caused by oxidative dysfunction of Kv4.3 potassium channels, was recently identified in transgeni

288 le structures of TRPV1 and voltage-activated potassium channels, we engineered chimeras wherein trans

289 ccompanied by increased mRNA levels of these potassium channels when compared with mRNA expression in

290 ian hnRNP U, result in dysfunction of a Slo2 potassium channel, which is critical to neuronal functio

291 splicing defects in voltage-gated sodium and potassium channels, which alter their electrophysiologic

292 and AIS clustering of PSD93 and also of Kv1 potassium channels, which directly bind PSD93.

293 ls express Kv7.4 and Kv7.5 voltage-dependent potassium channels, which have each been implicated as r

294 through the activation of calcium-dependent potassium channels, which usually act to reduce action p

295 reduced the function of calcium-activated BK potassium channels, whose activation depends on their ti

296 plexes formed with integrin-alpha5 and KCNB1 potassium channel wild type or epilepsy-susceptibility v

297 blocking small conductance calcium-activated potassium channels with apamin.

298 le to increased association of dendritic Kv4 potassium channels with auxiliary KChIP subunits.

299 diated expression of exogenous transmembrane potassium channels with high contrast and resolution.

300 blocking large conductance calcium-activated potassium channels with iberiotoxin, and is abolished by