ライフサイエンスコーパス: powerful

1 oral control of gene expression are the most powerful.

2 Chemical reaction networks (CRNs) provide a powerful abstraction to formally represent complex bioch

3 droughts, cold snaps, and hurricanes can be powerful agents of natural selection, producing acute se

4 e comparatively underexplored, but provide a powerful alternative strategy to current approaches, con

5 erformances, LM nanozymes were employed as a powerful alternative to the natural enzyme in a traditio

6 could represent an interesting and even more powerful alternative.

7 The powerful analgesic effects of opioid drugs have captivat

8 r, different studies have justified the more powerful analyses of multi-platform data.

9 rotocol based on mass spectrometry is a very powerful analytical approach, but it is not practical fo

10 The roles of biosensors as powerful analytical tools are emphasized for the detecti

11 he construction of these devices, leading to powerful analytical tools that remove the need for exter

12 One class classifier is a powerful and devoted for non-targeted analysis.

13 PFC and VTA DAergic activity, demonstrating powerful and functional neuroprotective effects against

14 hemical aptamer-based (E-AB) sensors offer a powerful and general means for analyte detection in comp

15 x datasets through functions which link to a powerful and interactive visualization user interface, T

16 pectroscopy-based online monitoring offers a powerful and novel route for characterizing system param

17 This is a powerful and often non-intuitive approach for complex mo

18 n a cold "thermometer" circuit that provides powerful and persistent inhibition to brain centers invo

19 Phosphorylation is a powerful and reversible mechanism regulating ion channel

20 he performance of our method is consistently powerful and robust across different settings with diffe

21 MCC-SP has powerful and robust performance in identifying the pathw

22 We develop here an intuitive, powerful and simple-to-implement approach for mitigation

23 on of these methods represents a potentially powerful and specific approach for the characterization

24 orchestrates population activity through its powerful and sustained feedforward inhibition.

25 Systems science offers powerful and underused tools to accelerate our ability t

26 Biologging has emerged as one of the most powerful and widely used technologies in ethology and ec

27 These results establish C. elegans as a powerful animal model to study the induction and modulat

28 bioactive peroxides are best known for their powerful antimalarial activities, and they also show sub

29 Honey has been valued as a powerful antimicrobial since ancient times.

30 lement RNA-protein interactions to repurpose powerful antiviral chromatin silencing machinery for sex

31 ociated Rossmann fold domain(6), sculpting a powerful antiviral response(7-10) that can drive viruses

32 Genome editing has powerful applications in research, healthcare, and agric

33 is now starting to quickly gather pace as a powerful approach for control of enantioselectivity in r

34 Proximity labeling is a powerful approach for detecting protein-protein interact

35 udy demonstrates a novel, rapid, facile, and powerful approach for identification of maggot species i

36 Subtiligase-catalyzed peptide ligation is a powerful approach for site-specific protein bioconjugati

37 hat promote select pathways is emerging as a powerful approach for therapeutic drug discovery.

38 A powerful approach is angle-resolved photoelectron spectr

39 hPSCs) and developing mouse neurons offers a powerful approach to compare genetic and epigenetic path

40 Scenario-based biodiversity modelling is a powerful approach to evaluate how possible future socio-

41 A powerful approach to examine the personalized biology of

42 Chromatin accessibility mapping is a powerful approach to identify potential regulatory eleme

43 Biclustering has emerged as a powerful approach to identifying functional patterns in

44 ire brain regions to single cells makes it a powerful approach to investigate the effects of stress f

45 Perturbation biology is a powerful approach to modeling quantitative cellular beha

46 Live-cell RNA imaging is a powerful approach to observe the real-time dynamics of R

47 A powerful approach to study Mtb metabolism as a whole, ra

48 monstrate that multiomics data analysis is a powerful approach to unravel the functional mechanisms u

49 this whole-animal Drosophila model provide a powerful approach towards the identification and therape

50 This approach opens a powerful avenue for studying, at the single particle lev

51 er a variety of substrates, thus bestowing a powerful avenue to access tri- and tetrasubstituted pyri

52 ard translocation of the blocker, provides a powerful avenue to investigate the selectivity of the bi

53 east partially mechanistically linked to the powerful BDNF-TrkB neurotrophic signaling system.

54 endered molecular dynamics (MD) simulation a powerful biophysical tool to investigate a wide range of

55 ization of non-natural GPA peptides by these powerful biosynthetic enzymes.

56 Using powerful bootstrapping and random forest (RF) approaches

57 Ynamides are among the most powerful building blocks in organic synthesis and have b

58 Phylogenetic comparative methods are powerful but presently under-utilized ways to identify m

59 otherapy from a pipe dream to an established powerful cancer treatment modality.

60 gh pCO(2) environments, making this system a powerful candidate for investigating acclimatization and

61 s the evaluation of V-ATPases as a novel and powerful class of anticancer targets.

62 The powerful combination of NMR, MD, and aMD methodologies a

63 This powerful combination of techniques allows us to obtain v

64 ions should feature to optimise their use as powerful community resources for crop research, developm

65 Array programming provides a powerful, compact and expressive syntax for accessing, m

66 ully substitute for on-site data, they are a powerful component of recreation research and visitor ma

67 Fangcang shelter hospitals could be powerful components of national responses to the COVID-1

68 Molecular dynamics (MD) is a powerful computational method for studying atomic/molecu

69 ost of the genes, subsequent reanalysis with powerful computational methods and larger databases led

70 s or her head so that an eavesdropper with a powerful computer-who sees the responses to random input

71 We combine this powerful CRISPR-Cas assay with a fluorescence-based poin

72 ifference between the two eyes' images, is a powerful cue to generate the 3D depth percept known as s

73 Several powerful culture-independent tools, in particular metage

74 re achieved, including variants that involve powerful dearomatizations and medium ring formations.

75 CRISPR-Cas systems provide a uniquely powerful defense because they can adapt to newly encount

76 Machine learning (ML) provides powerful dimensionality reduction tools.

77 mental and theoretical investigation of more powerful directed types of synaptic plasticity.

78 uch faster and safer thanks to the advent of powerful electron accelerators and high-rate electron be

79 The powerful electron accepting ability of fullerenes makes

80 aterials to develop increasingly complex and powerful electronic devices.

81 Imaging mass spectrometry (IMS) is a powerful emerging tool for mapping the spatial distribut

82 Ivermectin is a powerful endectocide, which reduces the incidence of vec

83 ed to be toxic, but recently recognized as a powerful endogenous antioxidant of physiologic importanc

84 Bottom-up subsystem analysis is a powerful engine for generating testable hypotheses about

85 These changes in language were powerful enough to predict children's science interest a

86 reported to demonstrate reduction potentials powerful enough to reduce benzene.

87 Our work shows that genome sequencing is a powerful epidemiological tool to characterize the serova

88 s of 1-sulfonylcyclopropanols, as stable yet powerful equivalents of the corresponding cyclopropanone

89 The location of energy dissipation in powerful extragalactic jets is currently unknown, with i

90 Lack of regular exercise was the most powerful factor to be associated with a higher risk of A

91 A powerful feature of adaptive memory is its inherent flex

92 This study provides a simple but powerful framework for advancing SI in mainstream cereal

93 ise of the proposed method as a flexible and powerful framework for exploring imaging genetic effects

94 Our approach provides a powerful framework for linking short- and longer term po

95 In this article, we propose a flexible and powerful framework for mining regional imaging genetic a

96 This approach offers a powerful framework to identify neurodevelopmental proces

97 n monogenetic cause of ASD, has emerged as a powerful gateway for exploring underlying mechanisms of

98 ad-specific approach to TBI in Drosophila, a powerful genetic system that shares many conserved genes

99 e knowledge extraction, orthology search and powerful graph algorithms to create navigable pathways t

100 usly coral-rich reefs.(6-8) Discovery of the powerful grazing capability of the Caribbean's largest h

101 mportant source of nitrous oxide (N(2) O), a powerful greenhouse gas, and increasing SOC may influenc

102 Powerful high-resolution imaging tools have been in deve

103 technique into one of the most versatile and powerful imaging methods of the nanoscale over the past

104 These studies demonstrate a powerful in situ optical battery platform for unraveling

105 is review, we discuss tools that have proven powerful in the investigation of nucleosome and chromati

106 ight the modulation of behavioral state as a powerful independent means through which individual gene

107 onary artery disease, (18)F-NaF PET provides powerful independent prediction of fatal or nonfatal myo

108 of chiral amino acids and sugars could be a powerful indicator for extant or extinct life on another

109 Copyback defective virus genomes (DVGs) are powerful inducers of innate immune responses both in vit

110 Moreover, it yields powerful insights into the electronic interactions at pl

111 Endurance exercise is the most powerful intervention for promoting mitochondrial functi

112 ing of these disorders, leading to novel and powerful interventions and even to preventing their init

113 eks in the absence of methane, making them a powerful marker for active as well as past methane leaks

114 we propose a contagion model as a simple and powerful mathematical approach for predicting the spatia

115 Using the powerful matrix-free assay of co-sedimentation analytica

116 ) suggest that the sharing economy may offer powerful means for improving resource efficiency and red

117 ches for controlling Ca(2+) channels provide powerful means for modulating diverse Ca(2+)-specific bi

118 Native mass spectrometry (MS) is a powerful means for studying macromolecular protein assem

119 l molecules with optical tweezers provides a powerful means of interrogating the structure and foldin

120 Catalytic cascade reactions represent a powerful means of rapidly leveraging molecular complexit

121 ng oligonucleotides together (ligation) is a powerful means of retrieving information from the nanosc

122 n as domino reactions) are arguably the most powerful means to achieve the construction of multiple r

123 on across structurally similar proteins is a powerful means to enable accurate inference of DNA-bindi

124 (Semi-) rational design has emerged as a powerful means to engineer proteins, but requires detail

125 Our study shows that Gys1 knockdown is a powerful means to prevent LD progression, but this appro

126 curacy in lifetime measurements and provides powerful means to quantify biochemical dynamics in livin

127 This method provides a powerful means to quantitatively interrogate macromolecu

128 cell malignancies, establishing itself as a powerful means to redirect the natural properties of T l

129 ion of Ca(V) 1/Ca(V) 2 channel activity is a powerful mechanism to regulate physiology, and there are

130 ble resource has the potential to serve as a powerful medium for probing the etiology of developmenta

131 ng moieties expand the applicability of this powerful method and its accessibility to non-specialist

132 be the same for all methods, LBL is the most powerful method for detecting GXE.

133 Cell ablation is a powerful method for elucidating the contributions of ind

134 lies of porous ions and represents a new and powerful method for the synthesis of porous solids with

135 idics with acoustics, we present a rapid and powerful method to size dependently control movement of

136 uorescence in situ hybridization (FISH) is a powerful method to visualize the spatial positions of sp

137 explored, RNA manipulation is emerging as a powerful mode of CRISPR-based engineering.

138 biotic features, they represent a unique and powerful model for comparing molecular pathways involved

139 The yeast Saccharomyces cerevisiae is a powerful model system for systems-wide biology screens a

140 also further establishes the zebrafish as a powerful model to carry out longitudinal studies of valv

141 ly-conserved epithalamic structure that is a powerful modulator of anxiety- and depressive-like behav

142 Physical exercise is a powerful modulator of learning and memory.

143 MPRAs are powerful molecular genetics tools that can be used to sc

144 Second, reward-paired cues are powerful motivators and they can evoke pursuit in their

145 tailed bacteriophages and herpesviruses is a powerful nanomachine built by several copies of a large

146 survival strategies against one of the most powerful neutrophilic oxidants may provide novel insight

147 This work demonstrates a powerful new approach to hit-finding.

148 combination of saponin and phytosterols is a powerful new approach to structure oil-in-water emulsion

149 Cherry-niche is a powerful new method that enables cells expressing a fluo

150 Our proof-of-concept study provides a powerful new methodology for studying nucleosome organiz

151 n, Podxl(DeltaPod) and Podxl(+/-) mice offer powerful new mouse models to evaluate early biomarkers o

152 Recently, an array of powerful new neuroscience tools have provided unpreceden

153 cleic acid nanoparticles (NANPs) have become powerful new platforms as therapeutic and diagnostic too

154 genous promotor for Pdgfra was shown to be a powerful new tool for isolating and characterizing the p

155 eginning to provide social scientists with a powerful new toolbox they can use to better understand e

156 These findings introduce SOM-EFS as a powerful non-linear exploratory data analysis approach i

157 their expression in single cells provides a powerful novel approach to accurately define leukocyte c

158 ons involving the Mll1 (Kmt2a) gene generate powerful oncogenic fusion proteins, predominantly affect

159 mall effects on disease risk, GWAS provide a powerful opportunity to explore pathways and mechanisms

160 idizes bromide to hypobromous acid (HOBr), a powerful oxidant that promotes the formation of the sulf

161 ational dynamics in engineering studies is a powerful paradigm with which to engineer the next genera

162 In silico trials innovations represent a powerful pipeline for the prediction of the effects of s

163 ced level of self-organization and provide a powerful platform for investigating post-implantation em

164 lude that antibody-TTR fusions may provide a powerful platform for multimerizing antibody and Fab fra

165 We believe that this model represents a powerful platform to further investigate the mechanisms

166 Numerous experiments utilizing powerful pulsed lasers with peak-intensity above air pho

167 ex, and the nanobody is demonstrated to be a powerful reagent for C3 detection in immunohistochemistr

168 ne(III) derivatives have been established as powerful reagents in organic transformations, but so far

169 he gene regulatory mechanisms, we designed a powerful regulatory analytical approach to identify the

170 rsal-ventral transcriptional maps provided a powerful resource for exploring genes and regulatory pat

171 Together these findings provide a powerful resource for unraveling unique compositions of

172 t poor T cell responses, whereas Aer induced powerful respiratory tract T cell responses but a low ti

173 Thus, lncRNAs can represent powerful RNA machines.

174 sing annotation information), a scalable and powerful RV association test method that effectively inc

175 ntial therapeutic target by discovering more powerful sChoK inhibitors.

176 Larval engraftment is a powerful short-term transplant platform amenable to high

177 arious forms of rHuEPO and as such represent powerful, simple-to-use analytical tools to monitor the

178 uorescence in situ hybridization (FISH) is a powerful single-cell technique that harnesses nucleic ac

179 Moreover, a subset panel of the 12 most powerful SNPs is sufficient to separate the two pure spe

180 s that inactivate protein-coding genes are a powerful source of information about the phenotypic cons

181 of the ubiquitous atmospheric moisture is a powerful strategy allowing for decentralized access to p

182 reate functional complexity and represents a powerful strategy for constructing new materials.

183 into a versatile chemical entity would be a powerful strategy for introducing functional complexity

184 Metal ligand cooperativity is a powerful strategy in transition metal chemistry.

185 lthough top-down proteomics has emerged as a powerful strategy to characterize proteins in biological

186 This work reports a simple and powerful strategy to identify HCPs in antibody drug subs

187 cuity and bioorthogonality thus appears as a powerful strategy to rapidly access to sugar-based ligan

188 Knifefish may use this powerful suction-induced cavitation to cause physical da

189 nment, can convert defective Treg cells into powerful, super-activated Treg cells (SuperTreg cells) t

190 rotoxicity, thus validating that 4E-BP1 is a powerful suppressor of PD-linked pathogenic insults.

191 alpha,beta-unsaturated ketones constitutes a powerful synthetic transformation.

192 Drosophila melanogaster is a powerful system for characterizing alternative myosin is

193 Zebrafish models are a powerful system for discovery, live imaging, and functio

194 female germline stem cells (GSCs) provide a powerful system for studying Polycomb silencing.

195 y, and thermal stability make TNA aptamers a powerful system for the development of diagnostic and th

196 This powerful technique finds application in the enrichment o

197 In theory the most powerful technique for functional localization in cognit

198 Overall, this is a powerful technique that can be used for point-of-use det

199 Single molecule photobleaching is a powerful technique to measure the number of fluorescent

200 rials allows us to use big-data methods as a powerful technique to study these materials and to disco

201 ted likelihood calculations bring rigor to a powerful technique.

202 Besides offering powerful techniques for data analysis, ANNs provide a ne

203 MS-based metabolomics methods are powerful techniques to map the complex and interconnecte

204 Ribosome profiling (Ribo-seq) is a powerful technology for globally monitoring RNA translat

205 omatin accessibility sequencing has become a powerful technology for understanding epigenetic heterog

206 RNA sequencing (scRNA-seq) is a popular and powerful technology that allows you to profile the whole

207 Bioprinting is a powerful technology with the potential to transform medi

208 ination with high-throughput sequencing is a powerful technology with which to track single-cell clon

209 tatory inputs to granule cells that are more powerful than distal inputs and fail to depress with rep

210 T-FH was 63% (standard error (s.e.) 6%) more powerful than GWAS and 36% (s.e. 4%) more powerful than

211 re powerful than GWAS and 36% (s.e. 4%) more powerful than the trait-specific maximum of GWAS and GWA

212 Although powerful, the intein fusion approach suffers from premat

213 odification of bacterial function could be a powerful therapeutic strategy.

214 Our study points to CeA(GA) as a potential powerful therapeutic target for alleviating chronic pain

215 ment, have emerged as a class of potentially powerful therapeutics for neurodegenerative CNS diseases

216 kernel-based methods have been shown to be a powerful tool due to their flexibility in modeling the a

217 Strain-release-driven methodology is a powerful tool for accessing structural motifs, highly de

218 This new oligonucleotide class provides a powerful tool for antisense technology.

219 Single-cell RNA sequencing has emerged as a powerful tool for characterizing cells, but not all phen

220 Machine learning is a powerful tool for creating computational models relating

221 analyzing sPRE data outlined here provides a powerful tool for deepening our understanding of extreme

222 dispersive X-ray spectroscopy (TEM-EDX) is a powerful tool for determining these particle characteris

223 ity, we envision the current technology as a powerful tool for early warning and detection of low pat

224 Protein design is a powerful tool for elucidating mechanisms of function and

225 oth expert and non-expert users, making it a powerful tool for gaining novel insights into genome evo

226 ility-mass spectrometry (IM-MS) has become a powerful tool for glycan structural characterization due

227 when combined with Hi-C experiments, to be a powerful tool for investigating large-scale rearrangemen

228 ken together, our findings demonstrate a new powerful tool for investigating the mechanobiological me

229 es, PSI is successfully demonstrated to be a powerful tool for investigating the morphological charac

230 Such enhanced scattering is a powerful tool for light manipulation, but also leads to

231 Laser microsurgery is a powerful tool for neurobiology, used to ablate cells and

232 by native mass spectrometry has emerged as a powerful tool for obtaining insight into subunit diversi

233 nvestigation validates the CoGEF method as a powerful tool for predicting mechanochemical reactivity,

234 uminescence (CPL) emission spectroscopy is a powerful tool for probing the fundamental chiroptical fe

235 Proteomics is a powerful tool for protein expression analysis and is bec

236 f separation science and is expected to be a powerful tool for single cell proteomics.

237 fluorescent activity reporters has become a powerful tool for studying the function of the brain.

238 ll culture model of HEV infection provides a powerful tool for studying viral-host interactions that

239 This microarray will be a powerful tool for the development of component-resolved,

240 acterization of such antibodies represents a powerful tool for the development of correlates of prote

241 implicity and scalability of GBid makes it a powerful tool for the discovery/engineering of Fabs and

242 The humanization of animals is a powerful tool for the exploration of human disease patho

243 ngineering-assisted optical stimulation is a powerful tool for the study of neuronal circuits.

244 sform infrared spectroscopy has emerged as a powerful tool for tissue specimen investigation.

245 t nature of DISC, we anticipate it will be a powerful tool for unsupervised processing of high-throug

246 Single-molecule localization microscopy is a powerful tool for visualizing subcellular structures, in

247 f "memory of chirality" has been proven as a powerful tool in asymmetric synthesis, while flow chemis

248 ariance components analysis has emerged as a powerful tool in complex trait genetics, existing method

249 Consequently, TIMS may arise as a powerful tool in electrochemical metabolism studies.

250 s spectrometry has been demonstrated to be a powerful tool in lipidomics analysis in which the differ

251 the screening robot PROTEUS has emerged as a powerful tool in the search for novel perovskite-like ma

252 Mass spectrometry imaging is a powerful tool of increasing utility due to its ability t

253 o mass spectrometry (LC-MS) is emerging as a powerful tool that can provide both qualitative and quan

254 study establishes the CRISPR/dCas9 SAM as a powerful tool that enables activation of the entire C19M

255 Here we present SigProfilerSimulator, a powerful tool that is capable of simulating the mutation

256 It represents a powerful tool to achieve RGC-specific gene modulation, a

257 y applied in this setting because they are a powerful tool to analyze data with large number of predi

258 An AI is a powerful tool to assist physicians in the diagnosis of s

259 Crosslinking mass spectrometry is a powerful tool to assist the structure prediction of prot

260 on of AO-OCT, SDOCT, and microperimetry is a powerful tool to capture cone regeneration after vitreor

261 how that simple chemical heuristics can be a powerful tool to characterize topological matter.

262 Cattell's rule based on the scree plot is a powerful tool to determine the number of cell-types.

263 tution assays with proteoliposomes provide a powerful tool to elucidate the mechanism of neurotransmi

264 Accelerometry has proven a powerful tool to estimate energy expenditure, but requir

265 cted insertion-site sequencing (TraDIS) is a powerful tool to identify genes and networks which are i

266 Magicians' forcing techniques provide a powerful tool to investigate how natural implicit primes

267 eage tracing model, which provides us with a powerful tool to investigate the dynamic EMT process in

268 metry-based phosphoproteomics technique is a powerful tool to investigate the site-level phosphorylat

269 We propose that hPSCs represent a powerful tool to model human pancreatic endocrine develo

270 tric C-H amination via nitrene transfer is a powerful tool to prepare enantioenriched amine precursor

271 with radiolabeled exendin has proven to be a powerful tool to quantify beta-cell mass (BCM) in vivo.

272 This novel system provides a powerful tool to study hepatocyte biology, disease mecha

273 human stem cells have recently emerged as a powerful tool to study organ development and disease.

274 cted and widespread in nature, making them a powerful tool to study the function of the different dom

275 Single cell sequencing has become a powerful tool to study the genome of individual cells fo

276 ericytes may prove a precise and potentially powerful tool to treat microcirculation deficits, a comm

277 hat molecular encapsulation can be used as a powerful tool to tune intermolecular interactions and th

278 cule based synthetic approaches, providing a powerful tool when deployable on preparative-scale.

279 diates have emerged as a practical, mild and powerful tool.

280 igorous statistical mechanical analysis, are powerful tools for analyzing structural ensembles of chr

281 e and efficient genome modifications provide powerful tools for biological studies.

282 ontributions, which have recently emerged as powerful tools for building highly accurate PESs for rel

283 WSH scores are powerful tools for estimating variance in DNA methylatio

284 e-based approaches, these techniques provide powerful tools for greatly expanding the protein enginee

285 Field courses have been identified as powerful tools for inclusion and student success in scie

286 abolomics stands out here as one of the most powerful tools for investigating the interplay between t

287 Biomarkers have emerged as powerful tools for the diagnosis, prognosis, and predict

288 ivity, and functional alignment, have become powerful tools in cognitive neuroscience over the past d

289 These can one day become powerful tools in disease diagnosis, prognostic predicti

290 Paper-based DNA biosensors are powerful tools in point-of-care diagnostics since they a

291 olution mass spectrometry is one of the most powerful tools in this context.

292 Vaccines are powerful tools to develop immune memory to infectious di

293 Electrophysiological approaches provide powerful tools to further our understanding of how diffe

294 ic approaches have provided a growing set of powerful tools with which to study genome-wide patterns

295 and alkenes using electrophilic boranes is a powerful transition metal free methodology for forming C

296 by RNA interference (RNAi) has emerged as a powerful treatment strategy across a potentially broad r

297 In this piece we argue that analogies are a powerful way of driving policy discussions by rendering

298 n tetrazine and trans-cyclooctene (TCO) is a powerful way to control the release of bioactive agents

299 These tools are especially powerful when deconvoluting highly specialized microenvi

300 ment, and showed that the new method is more powerful with less Type I error than the other two metho