1 F in CSF and plasma in the HD-CSF cohort (20 pre-manifest and 40 manifest HD mutation carriers and 20

2 n brain mechanisms of emotion recognition in pre-manifest carriers of the abnormal Huntington's disea

3 egatively correlated with genetic markers of pre-manifest disease progression in distributed, largely

4 gly impaired in peripheral immune cells from pre-manifest human HD patients.

5 fest Huntington's disease): 16 subjects with pre-manifest Huntington's disease and 14 control subject

6 n structure and emotion recognition, and the pre-manifest Huntington's disease cohort did not have a

7  behavioural study of emotion recognition in pre-manifest Huntington's disease to date; and happiness

8                        Emotion processing in pre-manifest Huntington's disease was associated with re

9 mal Huntington's disease gene (subjects with pre-manifest Huntington's disease): 16 subjects with pre

10 Plasma and cerebrospinal fluid from control, pre-manifest, manifest and late manifest HD participants

11  chemokines are upregulated in the brains of pre-manifesting mouse models for Huntington's disease (H

12 en patients with HD and controls and between pre-manifest mutation carriers and those with clinical o

13     Using a well-characterized Thy1-alphaSyn pre-manifest Parkinson's disease mouse model overexpress

14  with early microglia activation observed in pre-manifest patients and indicate that mHTT gene expres

15 matory cytokines and chemokines are found in pre-manifest patients that correlate with pathogenesis.

16 n, we found increased neural activity in the pre-manifest subjects in response to all three emotions