ライフサイエンスコーパス: precise

1 ssay that is high-throughput, sensitive, and precise.

2 vage is crucial for cytokinesis and involves precise activation of the RhoGEF ECT2.

3 mong Earth's oldest, but has hitherto lacked precise age constraints.

4 We find precise alignment of sister chromatids at centromeres.

5 RNA is a continuous measure which allows for precise allele quantitation in loci where the RNA allele

6 Precise analysis of complex neural circuits requires hig

7 lasmon resonance curve and allows for a more precise analysis of the plasmonic response.

8 ng-read sequencing of cancer genomes for the precise analysis of their genetic instability.

9 rs, they have proved invaluable for creating precise and accurate timelines for past human and enviro

10 Precise and automated analysis of site-specific O-glycos

11 osed nanoplatform verify their potential for precise and controllable drug release with different app

12 f conventional tissue engineering methods by precise and controlled layer-by-layer assembly of biomat

13 ng upon contraction of many muscles are both precise and coordinated.

14 Precise and efficient genome modifications provide power

15 ut a genetically encoded editor that is both precise and efficient has not been described to date.

16 cular profiling has the potential to be more precise and objective than histological evaluation and m

17 ively target capillary pericytes may prove a precise and potentially powerful tool to treat microcirc

18 ut a known gene, clinical management is less precise, and it is impossible to offer predictive testin

19 Controllable, precise, and safe delivery of diagnostic biosensing devi

20 easure 8-OHdG and were found to be accurate, precise, and stable.

21 test-retest reliability, was 3-5 times more precise, and was 3-8 times more efficient than the stair

22 In vaccinology, the induction of precise antibody responses remains a cornerstone for nex

23 tural light-harvesting complexes (LHCs), the precise arrangement modulates interchromophoric interact

24 nt mNGS of blood products afforded rapid and precise assessment of pathogen identity, abundance, and

25 Precise assessment of the corneal condition is necessary

26 ions or replacements of short sequences, and precise base changes in plants(1-7).

27 The precise behavioral correlates of desynchronization and i

28 ain cerebellar output for driving temporally precise behaviors.

29 ation (AMD) and disease progression, but the precise biological function of HtrA1 in the eye and its

30 s (SVs) in the same brains and resolve their precise breakpoints.

31 ressure system, which is highly accurate and precise, but relatively inaccessible and difficult to us

32 hologic evidence, these markers promise more precise care.

33 ircle amplification (C2CA) is a specific and precise cascade nucleic acid amplification method consis

34 Thus, the precise cell types whose loss of mitochondrial activity

35 moter/enhancers to target gene expression to precise cell types.

36 However, the precise cellular changes defining this process as well a

37 To annotate the precise cellular composition of distinct tissue regions,

38 ignals for CD4 T cell responses, however the precise cellular interactions critical for OX40L provisi

39 rmation is proposed to enable the robust and precise changes in gene-regulatory programs during signa

40 highlight the VidaL system as a tool for the precise chemical modification of cellular proteins with

41 Atomically precise clusters can be used to create single-electron d

42 ange expansion are repeatedly converted into precise coadaptations of feather development and caroten

43 line antidepressant intervention, though the precise cognitive and computational mechanisms that expl

44 00 nm thickness), is exploited to deduce the precise composition of the intermixed phase in bulk-hete

45 However, the precise concentrations at which these biological actions

46 t roles in sensorimotor processing, however, precise connections between these major brain structures

47 To resolve the precise connectivity of these circuits, we first mapped

48 However, a lack of precise, contemporary information on gastric adenocarcin

49 Aside from the precise control in sophisticated on-surface synthesis, t

50 Optical tweezers offer precise control in the force range relevant for protein

51 The present study illustrates that a precise control of crystallographic defects and their di

52 ipole interactions opens the door for a more precise control of dye-dye interactions in artificial mu

53 iption is the main mechanism responsible for precise control of gene expression.

54 t in utero animal modeling work suggest that precise control of ionic flux (calcium, sodium, and pota

55 Precise control of organ growth and patterning is execut

56 We found that precise control of RanGTP levels, revealed by different

57 or a general catalytic solution that enables precise control of the C=C bond migration position, in b

58 ystals with desired structures relies on the precise control of the crystal formation process.

59 Here we demonstrate that precise control of the heteroepitaxy of colloidal polyhe

60 id perovskites on arbitrary substrates, with precise control of their thickness (from about 600 nanom

61 c-di-AMP signaling in bacteria and show that precise control of this second messenger is essential fo

62 eutical and agrochemical industries requires precise control over each distinct stereocenter, a feat

63 a prototype for a general approach to exert precise control over pore diameter in physisorbents.

64 1,4-benzenedicarboxylate (MnBDC) MOFs with a precise control over their morphology (bulk vs. layered)

65 signers appears effortless but reflects the precise coordination of both large-scale and local corti

66 We highlight how the precise coordination of multiple signaling pathways is r

67 We find that efferents transmit a precise copy of the motor signal and a single spike in t

68 as9-based genome editing strategy allows the precise correction of WAS mutations in up to 60% of huma

69 Knowledge about the precise cortical regions and connections supporting this

70 ppocampal inputs are necessary to maintain a precise cortical representation of space.

71 Precise costs are not available for Medicare Part C (Med

72 les the development of more controllable and precise CRISPR-Cas tools.

73 The PRECISE-DAPT, PARIS, and DAPT (bleeding component) risk

74 ochemical diversity as a single measure to a precise definition of its multidimensional and multiscal

75 the assembly of muscle functional units with precise definition of muscle shapes and topographical wi

76 t these potential functional roles need more precise definition, particularly using advanced technolo

77 Envision appeared to better estimate the precise degree of effect.

78 lated expression of Cre recombinase mediates precise deletion of genetic elements in a spatially- and

79 ormation exists for several A3 proteins, the precise details regarding deamination target selection a

80 ation: 'essential' information refers to the precise details that are necessary to assess the quality

81 The automated system provides precise detection and measurements of ocular misalignmen

82 is critical for probing cell biology and for precise detection of disease.

83 This novel technique allows for precise determination of Bell inequality parameters with

84 te prediction of regulators' DNA binding and precise determination of biologically significant bindin

85 -MS) was used for the accurate, feasible and precise determination of this analyte.

86 generally conserved across species, but the precise developmental and positional patterns of express

87 tudy shows that molecular diagnosis helps in precise diagnosis of CN1 and in prognosis, prompt medica

88 on of high-risk PC patients and lead to more precise diagnosis of IDC-P.

89 h the mean diameter, contesting the value of precise diameter determination in larger axons.

90 owel-like sound based on measurements of the precise dimensions of his extant vocal tract following C

91 sor techniques are expected to enable a more precise disease control, as sensors are sensitive, objec

92 However, little is known regarding their precise distribution, innervation, and function.

93 ensively studied, the process leading to the precise elaboration of their comb-like shapes remains el

94 In this paper, a simple, sensitive and precise electroanalytical method was developed using flo

95 ical feedback, the structure is suitable for precise electroporation control in single-cells.

96 nce of an OSRE1 in intron 1 are required for precise enhancement of hyperosmotic glutamine synthetase

97 While the precise epigenetic function of this modification has not

98 We aimed to obtain precise estimates and predictors of long-term pain relie

99 The precise etiology of CS is not fully defined.

100 The precise etiology of these disorders remains unknown.

101 d to improved signal-to-noise ratio and more precise evaluation of correlated neuronal activity.

102 eynolds-Averaged Navier Stokes, leading to a precise evaluation of the thermal load and drag reductio

103 Our work provides access to the precise fabrication of polymers featuring diradical char

104 Precise fabrication of semiconducting carbon nanotubes (

105 r series was highly uniform and adapted to a precise fit, with self-sharpening lower molar cusps.

106 The design allows precise foil tracking during imaging with high-speed det

107 Our study warns against precise forecasts of the evolution of epidemics based on

108 Notably, errors in precise forelimb placement emerged as a novel behavioral

109 minent mitotic phenotype upon NuMA loss, its precise function in the interphase nucleus remains elusi

110 a protein expressed in striated muscle whose precise function is unknown.

111 unt of research done in the past decade, the precise function of LRRK2 remains largely unknown.

112 een investigated for over 200 years, yet its precise function remains unknown.

113 stic studies will be needed to determine the precise functional effects of these variants on biology.

114 r importance in regulating plasticity, their precise functional mechanisms remain elusive.

115 to be highly activated in TNBC, however the precise functions of the ERK isoforms (ERK1 and ERK2) in

116 mall RNA therapeutics and the improvement of precise gene editing now pave the way to applications su

117 Precise gene editing of mitochondrial DNA (mtDNA) is ess

118 ngle-stranded oligodeoxynucleotides mediated precise gene editing rates, and effectively reduces on-t

119 This work establishes that precise gene editing to correct multiple distinct gene v

120 he generation of a more efficient system for precise gene integration in catfish and other aquacultur

121 Innate immune responses rely on rapid and precise gene regulation mediated by accessibility of reg

122 ground state and transition state or highly precise general base positioning.

123 This study establishes a precise genetic engineering platform for genetic studies

124 for expanding the arsenal of enzymes used in precise genome editing.

125 ew variants of CRISPR base editors that make precise genomic edits in rice protoplasts while minimizi

126 changes-e.g. linear or exponential-and their precise geographical loci.

127 he design and characterization of atomically precise GNRs, but strategies for realizing GNR metallici

128 bons that can also be regarded as atomically precise graphene quantum dots, as a new class of fluorop

129 Automated guttae assessment facilitates the precise identification and quantification of guttae char

130 Rapid and precise identification of cases and tracing of transmiss

131 difiable and genetic risk factors allow more precise identification of high-risk patients for early i

132 More precise identification of the neurobiological bases of c

133 As a result, the precise immunologic mechanisms mediating ACD are more co

134 Shock-recrystallised monazite yields a precise impact age of 2229 +/- 5 Ma, coeval with shock-r

135 ported for degradation in the cell body, the precise impact of disrupting retrograde transport on the

136 ps in biomacromolecules in solution provides precise information about conformational changes and var

137 So far, no precise information on cross-reactive IgE-epitopes of cy

138 ient with regards to mutation rates, but the precise insertion of exogenous DNA or gene knock-in via

139 otocol, we provide the technical details and precise instructions for translating digital information

140 olecular tools, tumour modelling systems and precise instrumentation together with important advances

141 Organogenesis requires precise interactions between a developing tissue and its

142 However, the precise intracellular pathway has not been identified, i

143 margins of dissected tumors to declare more precise intraoperative diagnosis by scanning all around

144 ure to a multilayer perceptron and generates precise, intuitive visualization of individual Alzheimer

145 g approaches with hiPSC-based models permits precise isogenic comparisons of human neurons and glia.

146 CRISPR-based genome engineering facilitates precise isogenic comparisons of variants across genetic

147 ical applications that require effective and precise isolation of subpopulations of exosomes.

148 erebral stem/progenitor cells) that consider precise lesion location and the specific functional impa

149 ough disordered media allows us to formulate precise links between the statistics of environmental ch

150 that cytoplasmic cilia assembly requires the precise localization of mRNAs encoding key axonemal cons

151 Instead, we activate at random, precise locations in time and space and use post hoc ana

152 e smokers versus nonsmokers.Conclusions: The precise locations occupied by pulmonary macrophages were

153 d is demonstrated to be able to identify the precise locations of lesion sites in human subjects.

154 uncertainty associated with measurements at precise locations or points in time.

155 Microfluidic droplet generation affords precise, low volume, high throughput opportunities for m

156 The method showed to be precise (<6.9%) and accurate (recoveries using a certifi

157 lity of synthesizing compounds with electron-precise M=B triple bonds analogous to classical carbyne

158 e [2], limiting ecological understanding and precise management of migratory populations in expansive

159 vances in metasurface nanofabrication enable precise manipulation of light-matter interactions at sub

160 This signature enables precise mapping of core fragility regions in known CFSs

161 escent protein that enables spatiotemporally precise marking, erasing, and remarking of active neuron

162 The mechanisms for this precise matching between OSNs and PNs have been studied

163 By integrating precise measurement and actuation hardware into a single

164 Here, a facile and precise measurement method is reported for screening cel

165 ultispectral retinal imaging device obtained precise measurements of retinal reflectance over space a

166 Here, we report precise measurements of the stable isotopic composition

167 ilar sizes (CO(2)/N(2) and CO(2)/CH(4)), via precise mechanical control of the pore size aperture in

168 Despite their critical roles, the precise mechanics governing TRM cell reactivation in sit

169 However, the precise mechanics of these functions are little understo

170 st notably Mud/NuMA and cortical dynein, the precise mechanism by which spindles detect and align wit

171 The precise mechanism for the liquid-phase autoxidation of a

172 f mitophagy and proteasomal degradation, the precise mechanism leading to neurodegeneration in both s

173 However, their precise mechanism of action and their physiological impo

174 However, the precise mechanism of how NF2 mediates upstream signals t

175 pendent on its kinase activity; however, the precise mechanism of TTBK2 action has so far not been fu

176 hila will enable the characterization of the precise mechanism(s) by which various CI regulators modu

177 gical role in kidney fibrosis, and about the precise mechanisms and signalling pathways underlying th

178 retinal ganglion cells (RGCs), however, the precise mechanisms are still largely unknown.

179 reasingly used for cognitive enhancement but precise mechanisms are unknown.

180 e (JNK) and NF-kappaB pathways; however, the precise mechanisms governing the spatiotemporal activati

181 critical to dissecting and understanding the precise mechanisms of action of cancer-related proteins

182 brane may define the threshold; however, the precise mechanisms remain to be further explored.

183 The precise mechanisms underlying these processes are incomp

184 %, higher signal-to-noise ratio by 31%, more precise metabolite quantification by 22%, and an increas

185 An electron-precise metal-boron triple bond was first observed in Bi

186 important for future studies in associating precise MICs with specific resistance alleles.

187 s thus enable non-invasive, spatiotemporally precise modulation of the microtubule cytoskeleton in li

188 emerging imaging techniques now enable more precise molecular characterization of tumors, multigenet

189 inhibition of serine proteases, although the precise molecular details remain unclear owing to the la

190 This precise molecular mechanism for SAMHD1 catalysis, reveal

191 tream transcriptome analyses and can lead to precise molecular mechanisms for understanding complex h

192 s in behavior, but little is known about the precise molecular mechanisms that underlie this process.

193 etics, physiologically relevant affinity and precise molecular specificity for ACh of its predecessor

194 erpolarization can be used as a tool for the precise monitoring of chemical transformations by hyperp

195 Moreover, the precise multicomponent self-assembly of a Sierpinski tri

196 mologous recombination processes has enabled precise, multiplex editing of microbial genomes and the

197 e use genome engineering to demonstrate that precise mutation of hth 3' UTR sites for BX-C miRNAs or

198 The recent advent of atomically precise nanochemistry has opened new horizons.

199 Achieving precise nanopore topologies in graphene using top-down l

200 on transfer only via the D1 branch, with the precise nature of primary excitation and the factors tha

201 Outstanding questions concern the precise nature of the intermediates between N(2) and NH(

202 , we first discuss how to achieve atomically precise NCs and determine their total structures.

203 is of shaped metal nanoparticles to meet the precise needs of emerging applications requires intentio

204 rsonalized medical therapies that target the precise needs of patients are a critically needed and ex

205 remodeling is important for the formation of precise neural circuitry, and its disruption has been li

206 Achieving temporally precise, noninvasive control over specific neural cell t

207 In summary, RecVs enable spatiotemporally precise optogenomic modifications that can facilitate de

208 ralization to novel images, also became less precise over time.

209 The precise pathogenetic mechanisms underlying these inferio

210 amilial forms of Parkinson's disease but the precise pathogenic mechanisms are unknown.

211 The precise pathomechanisms remain to be elucidated.

212 Caenorhabditis elegans by P. aeruginosa, the precise pathways and mechanism(s) of translational inhib

213 The precise pattern of motor neuron (MN) activation is essen

214 Precise patterns of synaptic connections between neurons

215 to organize into multicellular structures in precise patterns requires that they "recognize" one anot

216 ion-diffusion processes can likewise produce precise patterns, termed attractor patterns, that reform

217 strally diverse populations, prioritize more precise phenotypic measures, and evaluate evidence for s

218 MD, and aMD methodologies allows to obtain a precise picture of the subtle events directing the encap

219 r analysis and revealed a stronger, but less precise, point estimate than the cohort analysis of brot

220 vity, structural regularity, and molecularly precise porosity.

221 parameter that dictates the tessellation and precise positioning of hundreds of picolitre-sized dropl

222 pilot study demonstrated the feasibility of precised pre-surgical planning and reconstruction of lar

223 d calculating prediction uncertainty enabled precise prediction of post-treatment cartilage repair sc

224 Precise prediction on the therapeutic outcome of a MSC t

225 process, will help to build more robust and precise predictions.

226 There is currently a lack of precise predictive biomarkers for patient selection in c

227 The precise preparation of monodisperse nanomaterials is amo

228 Therefore, precise prepatterning by 3D printing allows the construc

229 EGFR-DLS provides a non-invasive method for precise quantification of EGFR mutation status in NSCLC

230 A precise quantification of insect chitin is needed in ord

231 g improves this issue, it is not amenable to precise quantitation, which limits its utility for diffe

232 However, the precise quantities and the implication for the elicitati

233 a, a computational method for estimating the precise rate of such stochastic events using pedigree-ba

234 des studied (R2 > 0.999); it is accurate and precise (recoveries of 87-115%, relative standard deviat

235 Precise regulation of integrin-mediated adhesion is impo

236 h hydrolytic and signaling functions require precise regulation of lysosomal cholesterol content.

237 aging and biosensing, but their functions as precise regulators in living systems are still limited.

238 The precise relationship between frontotemporal dementia (FT

239 An accurate understanding of the precise relationship between time-to-antibiotics and mor

240 the shape of SDSL ESR spectra are known, its precise relationship with protein structure and dynamics

241 n action and perception is determined by how precise (reliable) it is expected to be.

242 cortex, we observed reliable and temporally precise responses to speech; these patterns transformed

243 ins, we demonstrate that the method delivers precise results even with low, near-native amounts of re

244 esting (delayed recall) revealed a brief but precise return-of-tuning to the CS+ in visual cortex acc

245 However, our understanding of its precise role in binocular processes is currently lacking

246 ll-cell adhesion is actin-dependent, but the precise role of actin in maintaining cell-cell adhesion

247 However, the precise role of GR in the pathophysiology of AD remains

248 However, the precise role of IL-2 in the maintenance and function of

249 To elucidate the precise role of iNKT cells in AD development of NC mice,

250 obamides remain to be characterized, and the precise role of the bza operon protein CobT is unclear.

251 To this end, here we determined the precise role of the vimentin intermediate filament syste

252 However, the precise role that oral microbes play in the extraoral or

253 eas might contribute to such learning, their precise roles and the neural mechanisms underlying them

254 The precise roles of the five remaining genes (Flcn, Map1lc3

255 e, where the hydrodynamic force then induces precise rotation of the cell inside the chamber.

256 By investigating how temporally precise SC inhibition influenced behavioral performance

257 ological features were recently proposed for precise selection of HCC patients for transplantation.

258 termed attractor patterns, that reform their precise shape after being perturbed.

259 EPA benefits from a precise signal recording and analysis method which leads

260 plants, including nonvascular plants, their precise signaling properties and molecular targets are n

261 The precise signals controlling tissue-specific adaptation a

262 The adaptations allow for highly precise site-specific glycan monitoring with minimum sam

263 Herein, we demonstrate that precise solute-solute separation can be achieved using p

264 ine base editor and tested their utility for precise somatic engineering of missense mutations in key

265 otoCORMs) are chemical agents that allow for precise spatial and temporal control over the CO release

266 modes in both hemispheres and discuss their precise spatial extent, and also perform predictions of

267 r than retraction-tuned units and encode the precise spatial location of surface ridges with higher a

268 euron accord with its selectivity by obeying precise spatial patterns.

269 s are sensed and signaled due to the lack of precise spatiotemporal control in vivo.

270 ated molecular motors because one can direct precise spatiotemporal inputs while conducting reactions

271 The precise stoichiometry of each component that permits thi

272 rticular emphasis is placed on analyzing the precise structural regulation of 2D CCFs.

273 d effect transistors, and p-n junctions with precise sub-mum spatial control, and a rectification rat

274 In pro-B cells PTBP1 ensures precise synchronisation of the activity of cyclin depend

275 the evolution of these variations requires a precise synchronization of the considered environmental

276 CRISPR-RfxCas13d (CasRx) is an effective and precise system to deplete specific mRNA transcripts in z

277 sted and computational drug design, allowing precise tailoring of inhibitors to the enzyme's electros

278 cteristics of the tumor microenvironment for precise targeting have been designed.

279 Precise targeting of stem-directed antibody responses to

280 ences, thereby revealing an a priori hidden, precise temporal structure of population responses.

281 are isolable to different nodes and are more precise than the behavioral latency of stopping.

282 ate using all collected samples was 25% more precise than the original density estimate, and the mode

283 s strong implications for the development of precise therapeutic strategies.

284 The precise time window during which spring weather advances

285 ty to deliver two coherent X-ray pulses with precise time-delays ranging from a few femtoseconds to n

286 omponent of neuronal communication and their precise timing is critical for processes like learning,

287 and produce movements in the real world with precise timing is critical for survival in animals, incl

288 otor routine whose execution resulted in the precise timing of their reward approaches.

289 mal biological and disease processes warrant precise tools for modulation.

290 The selective and precise transformation of 1 into 1-OTf-Pd(NP) was charac

291 ion of enzymes in space and time enables the precise transmission and integration of intracellular si

292 ups is possible and may open the way to more precise treatment, but more efforts need to be devoted t

293 eumonia is not negligible, meticulous rules (precise triage, safe hospital path, high level of protec

294 nducible quorum sensing system which enables precise tunability of bacterial dynamics both at the pop

295 However, precise tuning of these aspects is largely missing in th

296 sm is a targetable vulnerability; however, a precise understanding of metabolic heterogeneity is requ

297 Moreover, the incapability of precise weight updates can lead to convergence problems

298 egradation protocols were found accurate and precise when applied to fruits, vegetable and soil sampl

299 to be highly accurate in blood but are less precise when used in older samples or in tissue types no

300 smaller than current devices and can provide precise (within 5 degrees C) and tunable heating from 37