ライフサイエンスコーパス: precisely

1 Taylor dispersion can resolve accurately and precisely.

2 ct mutant alleles within a single human cell precisely.

3 gurations to regulate the expression of Otx2 precisely.

4 ns on the cyclohexene ring can be controlled precisely.

5 ce drops on average even though instances of precisely 2 drops were rare.

6 te the Sting1(S365A/S365A) mutant mouse that precisely ablates IFN-dependent activities while preserv

7 red nicking gene editing can efficiently and precisely add large DNA segments into essential and mult

8 plet interface, the size of the pores can be precisely addressed, resulting in structurally colored p

9 tion of BDNF gene expression is essential to precisely adjust BDNF levels that are dysregulated in va

10 Along arms, sister chromatids are less precisely aligned, with inter-sister connections every ~

11 Nevertheless, the ability to precisely and accurately quantify retinal hemodynamics r

12 rowing because IGEs have been challenging to precisely and comprehensively locate in genomes.

13 sly along chromosomes and across cell types, precisely and comprehensively.

14 endogenous growth cone guidance machinery to precisely and non-invasively direct axon growth using li

15 ent beam such that the beam waist is aligned precisely and that stability is assured at the metal-die

16 there is some confusion as to what they mean precisely and which is most appropriate for a given situ

17 expression measurements, may be carried out precisely and without bias.

18 e, we have developed a synthetic strategy to precisely arrange any anisotropic colloidal nanoparticle

19 es, as well as temporal correlations decline precisely as predicted for a branching process.

20 establish cohesion between sister chromatids precisely as they are born during DNA replication.

21 planatory striatal miRNA-mRNA pairs that are precisely associated with the shape of CAG repeat depend

22 stick ensuring placement of acidic residues precisely at the catalytic centre but also seems to have

23 the zeolite's supercage with its Pb(2+) ion precisely at the center, a position of high symmetry.

24 of PACAP expression occurred in RTN neurons precisely at the time of birth, coinciding with exposure

25 The more precisely atomic coordinates are determined, the more ch

26 We propose that this is avoided by precisely balancing labile forms of synaptic plasticity

27 complementary means to probe these polymers, precisely because they are sensitive to different aspect

28 bounded optimality and true sub-optimality, precisely because young children have limited computatio

29 Centrioles are precisely built microtubule-based structures that assemb

30 the depth of the ablation can be controlled precisely by means of the pulse energy.

31 Force volume AFM can precisely capture the mechanical properties of biologica

32 Moreover, our model precisely captures 3D nanoparticle distributions at cell

33 d be a quick and accurate diagnostic tool to precisely characterize and distinguish benign from malig

34 t has not been possible, in living cells, to precisely characterize the respective contributions of t

35 cus is small, but it has not previously been precisely characterized.

36 enables a powerful complementary method for precisely characterizing compact multiplanet systems.

37 NN for TE classification, and can be used to precisely classify TEs in newly sequenced eukaryotic gen

38 t statistics, whereas central brain activity precisely codes information needed for behavior.

39 ed by operation near an exceptional point is precisely compensated by increasing laser noise.

40 A deterministic process can be precisely computer-simulated, thus allowing virtual expe

41 itic carbon nitride as "subnano reactors" to precisely confine multiple Fe and Cu atoms for NRR elect

42 re application of biophysical principles can precisely control assembly and function in cellular and

43 We find that we can precisely control both the dipole-dipole coupling betwee

44 g applications are all united by the need to precisely control complex microbial dynamics in spatiall

45 A lack of tools to precisely control gene expression has limited our abilit

46 complexity, cells have evolved mechanisms to precisely control gene programs in response to environme

47 However, the ability to precisely control its regioselectivity with well-establi

48 Biological photonic structures can precisely control light propagation, scattering, and emi

49 thermodynamic and kinetic differentiation to precisely control sequences and suppress tapering and mi

50 ion sites on monolayer or bilayer s-TMDs, we precisely control the nucleation and growth of diverse m

51 gand on gold nanoclusters shows potential to precisely control the number of surface ligands and to e

52 So far it has not been possible to precisely control the reaction sites nor their lateral o

53 M, CaMKII, and PP1, providing a mechanism to precisely control the sensitivity of synapses to calcium

54 Cells precisely control their mechanical properties to organiz

55 ygen concentration, the power density can be precisely controlled and substantially promoted by ~220%

56 thography, and microfluidic delivery to form precisely controlled attractor patterns and study the re

57 uNi, CoNi, and CoCu) with metal compositions precisely controlled by precursor ratios.

58 ntly, the H(2)O(2) formation kinetics can be precisely controlled by tailoring the degradation rates

59 distributed over the substrate surface, with precisely controlled concentrations down to <0.001% Re a

60 Precisely controlled deuterium labeling at specific site

61 compatible single crystalline substrate and precisely controlled growth conditions, which limit the

62 The combination of precisely controlled high dose delivery, shorter exposur

63 a new, broadly applicable technique for the precisely controlled high-throughput preparation of well

64 tical regulatory node whose activity must be precisely controlled in order for S. aureus and other pa

65 ed approaches for designing programmable and precisely controlled nanoscale architectures through spe

66 nging to solution-print an array of NWs with precisely controlled position and orientation.

67 We reveal that AGO10 expression is precisely controlled temporally and spatially by auxin,

68 but the necessary devices typically require precisely controlled volumes to reduce biases in concent

69 nt tissues, and local auxin concentration is precisely controlled.

70 Materials properties are improved by precisely controlling both the quantity and location of

71 Precisely controlling the activation of transcription fa

72 Precisely controlling the number of atoms and nanoarchit

73 egulator of pancreas development, yet how it precisely controls pancreatic cell fates has remained ob

74 e difference in the driven E and I responses precisely controls spike timing by forming a brief time

75 To move the body, the brain must precisely coordinate patterns of activity among diverse

76 Vertebrate appendage regeneration requires precisely coordinated remodeling of the transcriptional

77 Myosins generate force and motion by precisely coordinating their mechanical and chemical cyc

78 xcitatory and inhibitory synaptic inputs are precisely correlated, nearly canceling each other, somet

79 ry with temperature as the inverse of T(4) , precisely counteracting the T(4) dependence; hence, ther

80 design of interfacial oxide architectures to precisely create, control, and transport oxygen vacancie

81 ata combined with lead isotope analyses of a precisely dated (mid-eighth century to 818 CE) glass ass

82 Here we use precisely dated and highly resolved coral records from t

83 e by gene targeting in wild-type H9 cells to precisely define RFX6 expression and in parallel perform

84 simplicity: the input parameters clearly and precisely define the IBD segments that are reported, so

85 al studies and registries are needed to more precisely define the incidence rates, risk factors, prim

86 larization angle in stand-alone films can be precisely defined at the single pixel level and reconfig

87 s exhibit uniform channel diameters that are precisely defined by the diameter of their nanohoop cons

88 Moreover, the schemas have precisely defined measures of security against all adver

89 hout the need for protecting groups and with precisely defined nanoscale architectures.

90 ociated molecular patterns (HAMPs); however, precisely defined receptors and elicitors associated wit

91 Thus, this precisely defined set of residues represents a novel tar

92 ranslational mobility where they moved along precisely defined tracks.

93 ounts as a ''context change'' has never been precisely defined.

94 acts between NSD2 or NSD3 and the nucleosome precisely defines the position of the enzyme on the nucl

95 om the injection process that are useful for precisely defining the start of each separation and quan

96 Additional studies are needed to more precisely delineate the best strategies for optimizing i

97 We show that active enhancer units are precisely delineated by active transcription start sites

98 The ChIP-exo assay precisely delineates protein-DNA crosslinking patterns b

99 ssociated with a cell type) that needs to be precisely described.

100 The ability to precisely design large proteins with diverse shapes woul

101 and mutagenesis confirmed a structure with a precisely designed cavity that forms favorable interacti

102 A precisely designed chiral squaramide derivative is shown

103 Precisely designed H-Dots can be used as a promising the

104 e are no robust computational tools that are precisely designed to analyze 3'Seq data.

105 ch uses the principles of polymer physics to precisely detect changes in steric pressure.

106 distributed in the crust and the ability to precisely detect millimeter-scale deformation over broad

107 Structural analyses indicate that fSHAPE precisely detects nucleobases that hydrogen bond with pr

108 However, it has not been possible to precisely determine the interaction between neuronal act

109 cal methods are necessary to selectively and precisely determine these compounds content in grapes.

110 using Raman difference spectroscopy, thereby precisely determining the pK(a) of interest.

111 omers were synthesized with monomer sequence precisely dictated by the placement of reactive side cha

112 rmodynamic friction and the entropic cost of precisely directing a single control parameter.

113 suggests how next-generation experiments may precisely dissect the energetics of hybrid formation on

114 e strategies to specifically disrupt PNNs to precisely dissect their function.

115 s essential for onco-pharmacology studies to precisely document the hypoxic status of tumors both bef

116 strategy for the controllable synthesis of a precisely doped single cluster catalyst consisting of pa

117 dissociation-like state in mice, induced by precisely-dosed administration of ketamine or phencyclid

118 The ability to precisely engineer the doping of sub-nanometer bimetalli

119 perature using a semiconductor nanowire with precisely engineered asymmetry.

120 ons in gold complexes make it challenging to precisely establish the identity of gold-ion-induced hyd

121 Overall, we provide a new way to precisely estimate frequency coupling that sheds light o

122 r uncertainty stemming from our inability to precisely estimate key model parameters, such as the Equ

123 tation and WQS regression can accurately and precisely estimate the effects of mixtures in a variety

124 disease associations for micronutrients were precisely estimated in larger WHI cohorts (n = 76,691) b

125 ficient of these chemosensitizing agents was precisely evaluated by using fluorescent dyes to measure

126 on by varying their firing rate and patterns precisely fine-tuned through GABAergic interneurons.

127 It is important to uncover how precisely florigenic homologs contribute to flowering in

128 ation with NIR light at low power results in precisely focused phototoxicity effects in which human m

129 en when none of the points have been sampled precisely from the singularities.

130 astern Tibetan Plateau margin that are dated precisely from ~35.5 to 31 Ma by combined magneto- and a

131 Here, we present an approach to precisely generate PA on demand on specific organelle me

132 Precisely how a protein achieves such an optimal environ

133 eity at the single-cell level(13) means that precisely how and why nuclei reorganize remains an area

134 However, it is not known precisely how BDQ triggers cell death in Mycobacterium t

135 However, precisely how evolutionary variation in protein-protein

136 ng complex (gamma-TuRC) has been identified, precisely how gamma-TuRC nucleates a MT remains poorly u

137 ired for the late stages of sporulation, but precisely how it functions is unknown.

138 ed depth and scale, helping us to understand precisely how p53 controls gene regulation.

139 Yet precisely how Pax6 achieves this deeply homologous funct

140 ause after transcribing less than 100 bases; precisely how RNAPII pausing is enforced and regulated r

141 However, precisely how susceptibility to ferroptosis is dynamical

142 It is still unknown precisely how TALI is involved in intramolecular signal

143 Precisely how the paternal epigenome is reprogrammed in

144 However, it is unclear precisely how these beneficial effects are mediated.

145 l as more recent stressors are risk factors, precisely how these environmental influences interact wi

146 However, precisely how this process is controlled in time and sub

147 red by trained convolutional neural networks precisely identified features such as cells, cell juncti

148 oteins involved in pigment binding have been precisely identified through x-ray crystallography exper

149 small proportion of human eRNA loci has been precisely identified, limiting investigations of enhance

150 ore bronchial artery embolisation because it precisely identifies the source of haemorrhage and vascu

151 all MetaGeneHunt is a new way to quickly and precisely identify discrete protein domains in sequenced

152 Efforts to precisely identify tumor human leukocyte antigen (HLA) b

153 However, precisely identifying the allergens responsible for thes

154 lity to define the electrochemical potential precisely in time, consequently, have to be updated or r

155 ives oscillations of local cAMP levels to be precisely in-phase with Ca(2+) oscillations, whereas Ca(

156 More precisely, in these cases the medial dorsal cutaneous ne

157 this platform, Cas9 can be modified to more precisely incorporate exogenously supplied single-strand

158 exceedingly high surface area materials with precisely installed chemical features, which provide new

159 (MS)-based methods to delve more deeply and precisely into the biochemical state of cells and its pe

160 To compare different candidates precisely, it is crucial to understand the error range o

161 el-guided delivery profiles were designed to precisely lead to the drug exposure intended by clinicia

162 Nevertheless, master regulators or, more precisely, lineage-defining transcription factors do not

163 sensitive to viscosity, Coupa allowed us to precisely localize sites of mitochondria-lysosome contac

164 -wide association data, it is challenging to precisely localize the variants that affect complex trai

165 es a transduction pathway required to ensure precisely localized auxin biosynthesis, thereby facilita

166 rsion of Cas9, can be detected by STRIDE and precisely localized within the cell nucleus.

167 By precisely localizing gaze and actively controlling retin

168 scence resonance energy transfer sensors can precisely locate and measure compartmentalized cAMP, and

169 lf-powered escape and rescue system that can precisely locate the survivor position and point out the

170 Here, we present data that allow us to precisely locate titin domains axially along the thick f

171 OLE RNA by OapB requires a stem containing a precisely located single-nucleotide bulge and a GNRA tet

172 Surgical resection of tumours requires precisely locating and defining the margins between lesi

173 Thus, it has been challenging to precisely manipulate PNNs to rigorously investigate thei

174 cells have become available, enabling us to precisely map the contacts between the EBV episome(s) an

175 hase change material [Formula: see text], to precisely map thermal contours from the nanoscale to the

176 s of m(5)C in the murine leukemia virus RNA, precisely mapped its location, and showed that ALYREF, a

177 The fluorescent color switch in these cells precisely marked an unequivocal change in EMT status, de

178 ting aptamers into a two-dimensional pattern precisely matching the spatial arrangement of ED3 cluste

179 would be greatly enhanced by the ability to precisely measure behavior in freely moving conditions.

180 However, the ability to precisely measure naturalistic surprise has remained elu

181 levitation (MagLev), which promises to more precisely measure the density of proteins in solution.

182 natal aneuploidy screening to detect CMV and precisely measure the length of CMV fragments in human p

183 iginal science, replication science seeks to precisely measure the underlying effect size associated

184 erature gradient across the embryo, which is precisely measured by in vivo nanoscale thermometry usin

185 We precisely measured the decay width Gamma of the [Formula

186 ted due to the complexities of surveying and precisely measuring large forested areas.

187 er spectral estimation, which is critical to precisely measuring such correlations, we propose a mult

188 One strategy to precisely methylate the 2' oxygen is to use viral mRNA m

189 been successful in creating a catalytic site precisely mimicking that suggested for natural metallonu

190 Given its power of precisely modeling the mixed effects from multiple sourc

191 gene expression in the mammalian gut can be precisely modified in situ with a single oral dose.

192 viding mechanistic insight that allows us to precisely modulate immune responses in health and diseas

193 ing biotechnology armed with the capacity to precisely modulate protein-protein interaction in time a

194 The challenge lies in lack of methods to precisely modulate relative molecular orientation betwee

195 unction and (2) advances in technologies for precisely modulating these functions in a programmable m

196 cells and allergen-specific T(H)2 cells were precisely monitored before and after rhinovirus challeng

197 The high control allows us to precisely move an individual and specific molecular enti

198 Recent work has also bounded the cost of precisely moving a single degree of freedom.

199 This strategy depends precisely on the number of redox cycles applied chemical

200 ng back to [Au(25)SR(18)](-) and eliminating precisely one surface ligand.

201 all squamate reptiles, while symmetrical and precisely orchestrated deposition of hard tissue during

202 the first 2 hours of Drosophila development, precisely orchestrated nuclear cleavages, cytoskeletal r

203 m corneum where lipids are organized under a precisely ordered continuous structure, the removal of f

204 tic tissues in which functionality relies on precisely ordered structures.

205 truct molecular goniometers-instruments that precisely orient objects-and use them to dock a DNA-bind

206 These effects precisely paralleled previous reports of persistently (~

207 of NK cells to target malaria parasites more precisely, particularly through antibody-dependent mecha

208 We exploit the ability of inkjet to precisely pattern microdroplets at high resolution to en

209 rotein into four physicochemically distinct, precisely patterned 2D crystals via control of four clas

210 elies on action-like processes consisting of precisely patterned neural time-keeping activity in the

211 ting both microsaccades and ocular drifts to precisely position the image on the retina and adjust it

212 rication of complex synthetic tissues, where precisely positioned compartments perform coordinated ta

213 llular development depends on generating and precisely positioning distinct cell types within tissues

214 First, the device geometry is modified by precisely positioning junction-anchoring ligands on the

215 e elongation, apparently through its role in precisely positioning the +1 nucleosome.

216 edients into larval diets as a means to more precisely predict output, such as larval development tim

217 Thus, precisely predicting K(v) spatially has remained concept

218 es in many natural proteins are difficult to precisely program and thus challenging for computational

219 Metabolism during pregnancy is a dynamic and precisely programmed process, the failure of which can b

220 veloping neonatal gut microbiota needs to be precisely quantified.

221 rcuit function, and neuronal activity can be precisely quantified.

222 s screened from a fine-mapping population to precisely quantify the associated genomic variation in t

223 ion is complicated both by the difficulty of precisely quantifying diet composition and by definition

224 Our findings highlight the importance of precisely quantifying the evolving nature of the battery

225 t combines topology and magnetism to produce precisely quantized Hall resistance at zero magnetic fie

226 regulatory feedback to constantly assess and precisely react to their environment.

227 lometers, walking solitary foraging ants can precisely recapitulate routes of up to 100 m in complex

228 The use of nanophotonics to rapidly and precisely reconfigure light beams for the optical stimul

229 n simulations with a detailed feature map to precisely reconstruct the experimental environment.

230 commonly work over long genomic distances to precisely regulate spatiotemporal gene expression patter

231 mbrane fusion on the order of millisecond is precisely regulated by the assembly of SNAREs and access

232 the hypothesis that the Warburg effect is a precisely regulated developmental mechanism that is anom

233 infection and, thus, must be temporally and precisely regulated for successful infection.

234 However, how PPM1G activity is precisely regulated to control NF-kappaB transcription m

235 other transposons, its excision site can be precisely repaired without leaving footprints and it int

236 diting, this type of genetic mutation can be precisely repaired.

237 t time that the activity of dopamine neurons precisely represents the impulse vector (force exerted o

238 izing robotic arm equipped with the SPAS can precisely reproduce traditional Chinese calligraphy via

239 to Brownian motion can make it difficult to precisely resolve these conformational changes.

240 nly a small fraction of such sites have been precisely resolved on the human genome sequence(6).

241 tinas, we find that three bipolar cell types precisely restore input synapse numbers when 50% of cone

242 onsistent with these distributions were more precisely retrieved, and this schematic influence increa

243 gmentation method called Cellpose, which can precisely segment cells from a wide range of image types

244 of the semantic segmentation U-Net model to precisely segment mass lesions in MG images.

245 We report a series of precisely segmented polyethylene-like materials containi

246 example, living sensors could be designed to precisely sense disease biomarkers, such as by-products

247 rategy fabricated on paper, an automated and precisely sequenced solution transfer was enabled by sin

248 m and recover complex chemical patterns with precisely sized features in the ranges of tens or hundre

249 ificity by forming cooperative homodimers on precisely spaced and oriented DNA sites.

250 d liquid-like material properties, docked at precisely spaced intervals along cytoskeletal elements,

251 We developed an approach for precisely stenciling the structure of individual chromat

252 g the ferroelectric BaTiO(3) , production of precisely strain-engineered, substrate-released nanoscal

253 ive O-furanosylation reactions promoted by a precisely tailored bis-thiourea hydrogen-bond-donor cata

254 s-responsive upconversion nanoparticles that precisely target and respond to tumors via targeting the

255 t bacteria and the host make it difficult to precisely target bacterial functions without disrupting

256 gene expression, coupled with the ability to precisely target by genomic editing most areas of the ge

257 In order to precisely target expression of a gene of interest to par

258 However, syntheses pursuing precisely targeted mixed functionalities, such as multip

259 The pairing-dubbed happy hypoxia but more precisely termed silent hypoxemia-is especially bewilder

260 teral semicircular canal as a proxy to infer precisely the horizontal plane on dry skulls and in exti

261 nal data, however, are needed to define more precisely the level of efficacy of the doxycycline proph

262 s (HFSCs) isolated from HS patients and more precisely the outer root sheath cells (ORSCs).

263 38 bp transposable element (TE) sequences at precisely the same site in exon 4 in nine of the 10 cnr

264 those who conduct ancient DNA research, face precisely this challenge as it becomes clear that practi

265 -locked to cortical theta activity and fired precisely timed bursts after reward and punishment.

266 computing based learning systems to generate precisely timed control signal spikes for neuromorphic a

267 To determine the effects of precisely timed dopamine manipulations on the performanc

268 These results suggest that precisely timed dopamine signals have immediate and long

269 the timing of EOD production provides brief, precisely timed inhibition that effectively blocks respo

270 Together, our findings demonstrate that precisely timed motor learning improves recovery from de

271 Whisker stimuli evoked precisely timed single spikes in L1 interneurons, follow

272 ken together, these findings establish how a precisely timed spatiotemporal expression of Phf21b crea

273 ential of analog memory synapses to generate precisely timed spikes in SNNs is experimentally demonst

274 By precisely timing CRISPR-Cas9 delivery during early devel

275 By precisely titrating the number of neurons stimulated, we

276 As (mRNAs), provide a rapid means to respond precisely to different conditions.

277 the lower urinary tract (LUT) must be timed precisely to occur in appropriate behavioral contexts.

278 s of proteins with the same overall fold but precisely tunable geometries.

279 , atomically curved 2H-WS(2) nanosheets with precisely tunable strain and sulfur vacancies (S-vacanci

280 Moreover, this emission is precisely tunable through synthetic control of crystal w

281 d structure of composite catalysts have been precisely tuned by oxide doping and accurate control of

282 electronics and electric grids relies on the precisely tuned electrochemical dynamics and interaction

283 se findings suggest the R2lox active site is precisely tuned for achieving both selective heterobimet

284 ts that animals rely on feedback rather than precisely tuned neural controllers to compensate for mor

285 expansion of this toolset will provide more precisely tuned reagents for manipulating bonds in disti

286 e information and strong interactions can be precisely tuned(1).

287 intrinsic allostery of cGAS efficiently yet precisely tunes its activity.

288 To more precisely understand the role of TOP2A in mitosis, we us

289 But for such plasmon-driven chemistry to be precisely understood and modeled, the critical photoinit

290 man body to react appropriately and perceive precisely unusual or dangerous conditions in the real wo

291 male mice to record activation of MTCs while precisely varying inhalation frequency.

292 More precisely, we analyze the multiscale neural growth data

293 More precisely, we detect bursts of adaptive evolution in the

294 More precisely, we work with a Lagrangian formulation of the

295 as an area of clinical inquiry, determining precisely what differentiates the metastatic phenotype h

296 essential role in orchestrating cytokinesis, precisely what its functions are and how these functions

297 However, we still do not know precisely when these cells begin to develop the selectiv

298 eakens with doping and completely disappears precisely where superconductivity disappears.

299 complexes directly within the cell, to show precisely where these interactions occur and thus improv

300 Precisely why patients with PD-L1 negative tumors respon