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1 rocedure revolving around In(I)Cl as the key precursor.
2 sized desmosterol, the immediate cholesterol precursor.
3 dritic unit 4 was obtained from its tosylate precursor.
4 distribution of mature miRNAs from the same precursor.
5 ge methylation from the drug or its advanced precursor.
6 e triple-tryptophan motif (WWW) in the YtgCR precursor.
7 a conditionally essential amino acid and its precursor.
8 allyl-l-cysteine (SAC) to alliin, an allicin precursor.
9 in parallel rather than from an intermediate precursor.
10 ds, and cannabigerolic acid, the cannabinoid precursor.
11 esting in vivo transformation of sulfonamide precursors.
12 yltriazoles and aryldiazoacetates as carbene precursors.
13 iate a caldera collapse, despite only modest precursors.
14 differentiation, and survival of Trm and Trm precursors.
15 ication of the paraxial mesoderm in tail bud precursors.
16 todeboration of beta-amino gem-bis(boronate) precursors.
17 ainment of stable polymer colloids as carbon precursors.
18 building blocks from easily accessed achiral precursors.
19 it mostly functions to help maintain neural precursors.
20 uding LC3-membrane conjugation to autophagic precursors.
21 ors colocalized with tfap2a in distal tubule precursors.
22 bone marrow macrophages, known as osteoclast precursors.
23 the 5'-proximal short ORFs (uORFs) of piRNA precursors.
24 rmation can be restored with select arginine precursors.
25 OS, or were formed in vivo from unidentified precursors.
26 hropogenic unsaturated organics as potential precursors.
27 ,3-dienyl and cumulated 1,2-dienyl carbamate precursors.
28 odehydrogenation reaction of their nonplanar precursors.
29 for synthesizing valuable chemicals and fuel precursors.
30 vity, and genetic knockout of opioid peptide precursors.
31 endent positive selection of fetally derived precursors.
32 on of diarylmethyl and dialkyl benzimidazole precursors.
33 of intermediates derived from 3-oxo-mycolate precursors.
34 tionalized azetidines from readily available precursors.
35 s volatiles from carbonaceous chondrite-like precursors.
38 how that microdeletions at 13q12.2 in B-cell precursor acute lymphoblastic leukemia (BCP-ALL) elimina
39 cessed from common ortho-fluoro-ethynylarene precursors, allowing the heteroatoms to be installed at
41 ed direct connection between simple aromatic precursors and complex small organic molecules via arene
42 Adaptation was largest for constant-level precursors and did not occur for highly fluctuating prec
44 ation of native or near native peptidoglycan precursors and fragments by Escherichia coli PBP1B, allo
45 coupling reaction product distributions and precursors and help inform the development of the next g
46 alized bicyclopentanes using various radical precursors and heteroatom nucleophiles via a metallaphot
48 ne marrow revealing perturbed UPR in myeloid precursors and in vitro differentiation of primary CD34(
49 ble to elsewhere, and concentrations of PFAA precursors and long chained PFAA in biota were positivel
51 Many sterols, including cholesterol and its precursors and metabolites, are biologically active and
52 followed by decomposition of the metal salt precursors and nucleation/growth of multimetallic partic
54 ne (HMND), prompted the investigation of the precursors and pathways through which MND is produced an
55 microenvironments that nurture hematopoietic precursors and promote their self-renewal, proliferation
58 We demonstrate the roles of the amorphous precursors and the existence of an energy barrier before
59 ation, overaccumulation of 5.8S and 18S rRNA precursors, and an imbalanced 40S:60S ribosome subunit r
60 g UCP1, increased numbers of beige adipocyte precursors, and expanded UCP1-expressing cell clusters i
61 gest that SNA originates from pre-linguistic precursors, and pave the way to the investigation of the
64 the endoplasmic reticulum (ER), the peptide precursors are processed in the cis-Golgi by the subtila
65 itic nitrogen dopants induced by the diamine precursors, as demonstrated in mechanistic and computati
66 y of Integrator cleaves nascent capped piRNA precursors associated with promoter-proximal Pol II, res
67 as inexpensive bulk CuO, PbO, and Sb(2)S(3) precursors at room temperature and ambient pressure to g
68 w cytometric assay to identify patients with precursor B-cell ALL (B-ALL) at very low risk (VLR) of r
69 HistoryAn 18-year-old man was diagnosed with precursor B-cell lymphoblastic leukemia and underwent tr
71 Cl, Br) has been proposed as an alternative precursor because CO can easily desorb under electron ex
73 ncurrently fragment populations of different precursors by cycling through segments of a predefined p
75 ized by dehalogenation of a bromocyclocarbon precursor, C(18)Br(6), in 64% yield, by atomic manipulat
78 s, it subsequently increases oligodendrocyte precursor cell differentiation, oligodendrocyte generati
81 sic property of fetal hematopoietic stem and precursor cells (HSPCs) caused by high expression of the
82 macological stimulation of endogenous neural precursor cells (NPCs) may promote cognitive recovery an
83 rat Schwann cells (SCs) and oligodendrocyte precursor cells (OPCs) and explored the molecular mechan
84 itatory neurons and immature oligodendrocyte precursor cells (OPCs), and these contributed almost hal
86 decisions and the existence of committed TRM precursor cells in the circulatory TEFF compartment.
88 e that fear learning induces oligodendrocyte precursor cells to proliferate and differentiate into my
89 beta-catenin pathway in the lateral skeletal precursor cells, and does not influence the Sema3d pathw
91 odulates ferroportin expression on erythroid precursor cells, thereby lowering potentially toxic-free
92 related to its function in mammary stem and precursor cells, this is not the case for its function d
95 NA vaccination against the MACV glycoprotein precursor complex (GPC) and murine hybridoma technology
98 ltistep transformations preprogrammed in our precursors' design rely on highly selective and sequenti
99 hts into the nanoparticle growth process and precursor designs, enabling the systematic preparation o
100 on of alpha-halo ketone in amine as a halide precursor, different shaped nanocrystals without comprom
102 consisting of DIMER(G), DIMER(NG), and their precursor, e-GSE, increased the modulus of elasticity at
103 in part because of limited knowledge of the precursor emissions and the chemical environment of smok
105 major survival signal to maturing erythroid precursors (EPs) and is essential for terminal erythropo
106 ors and did not occur for highly fluctuating precursors, even when the two types of precursors had th
109 tically cyclize to form quinolinic acid, the precursor for de novo biosynthesis of nicotinamide adeni
110 (P(3) (B) )Co(H(2) ), serves as a competent precursor for hydrogen atom transfer to (t) Bu(3) ArO(.)
112 acting as a convenient and highly effective precursor for selective formation of bromo-substituted B
114 ous appeal as surface-binding linkers and as precursors for controlled graphene nanoribbon synthesis,
115 n and reactivity are used to install radical precursors for homolytic on-protein radical generation;
116 transmembrane transporters, all of which are precursors for impaired gut integrity and performance.
118 FFAs), which can serve as energy substrates, precursors for lipid synthesis, and mediators in cell si
119 muli-responsive materials are serving as the precursors for next-generation interactive materials.
120 ) and 1,6-hexamethylenediamine (HMD) are key precursors for nylon synthesis, which are currently prod
121 ntiopure building blocks, which are valuable precursors for supramolecular and materials chemistry to
122 and Br) in the presence of NiCl(2)/Zn as the precursors for the assumed Ni(0) complexant together wit
124 yanidometallates were fruitfully explored as precursors for the construction of diverse d-d or d-f co
125 espite being constrained to the single-chain precursor form, PK-R371A cleaves high-molecular-weight k
126 dvances in understanding the roles of B cell precursor frequency, B cell receptor affinity for antige
127 we report that the release of autophagosome precursors from recycling endosomes is mediated by DNM2-
128 mesityl) or by transmetalation with cuprous precursors from the corresponding deprotonated ligand.
129 al reagent (known as Baran aminating reagent precursor) from isobutyric acid and N-hydroxysuccinimide
130 s and on four families of glycosylated aroma precursors (GAPs) at the arrest of fruit phloem unloadin
133 ating precursors, even when the two types of precursors had the same mean level and both activated th
134 4,9-dibromoquinolino[7,8-h]quinoline (17) as precursors has granted the formation of a range of subst
135 n of complex molecular scaffolds from simple precursors, has been a long-standing challenge in organi
137 ough a one-pot reaction using [Ag(pz)](n) as precursor (Hpz=pyrazole) and further characterized by X-
139 ork highlights the importance of sulfonamide precursors in contributing to bioaccumulation of AFFF-as
140 chanically-activated nanostructured metallic precursors in nitrogen and consolidated by spark plasma
141 stulate a novel model for evolution of miRNA precursors in sea anemones and their relatives, revealin
144 rimary hepatic stellate cells (myofibroblast precursors in the liver) in vitro, and IL-1alpha is elev
146 hetic pathway, defined by (1) the fatty acid precursor, including linoleic acid (LA), arachidonic aci
147 modeling MCM10 deficiency in primary NK cell precursors, including patient-derived induced pluripoten
148 d can accommodate a diverse array of radical precursors, including those that generate alkyl, alpha-a
149 We propose that secondary structure of miRNA precursors induced by their MTA-dependent m(6)A methylat
150 f three BCR KI lines expressing native human precursors, instead of computationally inferred germline
151 lso participates in a network of piRNA-piRNA precursor interactions that initiate piRNA production fr
152 red for the differentiation of distal tubule precursors into early stage distal convoluted tubules (D
157 al examples and beginning with HPLC-MS/MS in precursor ion scan mode, after extraction and thiol-spec
158 DDA enabled higher peak intensities for the precursor ions (median: 18 times in negative mode and 21
159 andem mass scan (2D MS/MS scan) in which all precursor ions and their subsequent product ions are bot
161 hree drug conditions: 150 mg of the dopamine precursor L-dopa, 2 mg of the D2 receptor antagonist hal
163 fallopian tubes contains multiple concurrent precursor lesions, including serous tubal intraepithelia
164 t gaps in reactivity or require synthesis of precursor libraries comprising a large number of variant
166 ucture, and structures obtained at different precursor loadings enable observation of successive stag
169 d cationic PFAS represented 83% of the total precursor mass and were found primarily in the source an
170 .33); it is possible that an unmeasured PFBS precursor may be accumulating in biota and metabolizing
171 methyl-palmitate, in turn synthesized from a precursor metabolite generated in the isoleucine catabol
173 (III) ion forms the target heterotrimetallic precursor [Mn(II)(ptac)(3)-Na-Fe(III)(acac)(3)-Na-Mn(II)
174 has traditionally been minimized to promote precursor molecular ion formation, and therefore its val
175 induced deposition (FEBID) requires suitable precursor molecules and processes to obtain the pure met
177 Metabolic pathways not only provide the precursor molecules necessary for gene expression, but t
179 as an essential role in the selection of the precursor mRNA branch-site adenosine, the nucleophile fo
180 conversion of proliferating skeletal muscle precursors (myoblasts) to terminally-differentiated myoc
181 ones ranging from readily available chromone precursors, namely 3-halogenchromones, 3-formylchromones
183 nicotinamide adenine dinucleotide (NAD(+) ) precursor nicotinamide riboside (NR) boosts NAD(+) level
185 n to exist in corals, or from a dense liquid precursor, observed in synthetic systems but never in bi
187 found to be the most important intermediate precursor of acrylamide formed in coffee during roasting
188 sting that nitromethane may be the immediate precursor of chloropicrin, although nitromethane is unli
191 stablish synthesis of 8-hydroxygeraniol, the precursor of monoterpene indole alkaloids, and cannabige
192 y central nervous system constituent and the precursor of several molecules that regulate the resolut
196 ntermediates, the thioimidate and the cyclic precursor of the thiazoline product, and determined the
197 is probably responsible for cleavage of the precursor of the transcription factor Nrf1 in higher euk
199 pogenesis in the liver(4-6), in which carbon precursors of acetyl-CoA are converted into fatty acids.
204 granule lumen, which is required to process precursors of granzymes and perforin to their mature for
208 anosomes, and to produce cysteinyldopas, the precursors of pheomelanin synthesis made in melanosomes
209 ree fatty acids and amino acids, among which precursors of VOCs, characterized the late stages of rip
210 dal atrophy may involve inflammatory-related precursors on a background of genetic predisposition.
211 of a screening program to detect anal cancer precursors on the incidence of cases of invasive anal sq
212 strong base for deprotonation of imidazolium precursors or the use of specifically-synthesized precur
213 replacer with 5-hydroxytryptophan (serotonin precursor) or fluoxetine (reuptake inhibitor) increases
214 Se(3) and subsequent reaction with a copper precursor, (P-Se)+Cu, and 2) the synthesis of copper pho
215 the aptamer enhanced proteolytic cleavage of precursor p66/p66 by HIV-1 protease, suggesting that it
217 roles of the leader peptide and of the RiPP precursor peptide recognition element, present in myriad
224 teraction between astrocyte-released amyloid precursor protein (APP) and death receptor-6 (DR6) on MN
225 ExNef caused a redistribution of amyloid precursor protein (APP) and Tau to lipid rafts and incre
226 imer's disease (fAD) mutations alter amyloid precursor protein (APP) cleavage by gamma-secretase, inc
227 se, butyrylcholinesterase, beta-site amyloid precursor protein (APP) cleaving enzyme-1 (BACE-1), and
228 as compared to rodent Abeta, the rat Amyloid Precursor Protein (App) gene was mutated to produce huma
230 tical slices from male wild-type and amyloid precursor protein (APP) knock-out (KO) mice to assess th
231 g human genes such as those encoding amyloid precursor protein (APP) or presenilins (PSEN1 or PSEN2)
233 ted neurons extracted from preplaque amyloid precursor protein (APP) transgenic rats were found to pr
234 a42) peptide generated from the amyloid-beta precursor protein (APP) via cleavages by beta- and gamma
235 otal-Tau, phosphorylated-Tau (pTau), amyloid precursor protein (APP), GFAP, Iba1, alphaII-spectrin, a
238 at is generated by thrombin from the zymogen precursor protein C in a reaction greatly accelerated by
239 idogenic processing enzyme beta-site amyloid precursor protein cleaving enzyme 1, and both total and
240 "remapping." We tested remapping in amyloid precursor protein knockin (APP-KI) mice with impaired sp
241 ransgenic mice expressing human beta-amyloid precursor protein Swedish (Tg-SwDI), a model of cerebrov
242 hippocampal levels of phosphorylated amyloid precursor protein, its pro-amyloidogenic processing enzy
243 ed by mutations in the gene encoding amyloid precursor protein, whose processing can result in format
245 e both contribute to the removal of arrested precursor proteins that specifically accumulate in these
250 c C4-epimerase that generates the UDP-GalNAc precursors required by the Pel synthase machinery for po
252 hermore, analysis of the catalytically inert precursor RNP demonstrated the structural impact of the
258 result from DMSO reacting with MA(+) in the precursor solution are responsible for the formation of
260 se include three negative CIEs (i.e., Marshi/Precursor, Spelae/Initial, Tilmanni/Main) with sharp pos
261 y define and follow myelodysplastic syndrome precursor states, such as clonal haematopoiesis of indet
263 rsors or the use of specifically-synthesized precursors such as NHC(H)[HCO(3)] salts or NHC-CO(2) add
264 yl)- cyclohexanes by direct hydrogenation of precursor tetrakis- or hexakis- (trifluoromethyl)benzene
266 continued passage of the partially processed precursors through the secretory pathway, and for subseq
267 naceous plants NA serves as the biosynthetic precursor to 2' -deoxymugineic acid (DMA), a related Fe
270 d by graphene oxide and including a silicate precursor to grow a strong, mesoporous capsule shell sur
272 ot a neoplastic condition, it is an emerging precursor to neoplastic high-grade B-cell lymphoprolifer
273 und was designed from sequence to target the precursor to oncogenic microRNA-21 (pre-miR-21) for enzy
275 biosynthesis of branched-chain amino acids (precursors to branched-chain fatty acids) by imazapyr sh
277 Herein, we unravel the evolution pathway of precursors to ORR-active catalyst comprised exclusively
278 distinct diastereomeric chiral isoflavonoid precursors to the chiral pterocarpans, (-)- and (+)-medi
280 otected, primary 2-azidoamines are versatile precursors to vicinal diamines, which are among the most
281 drives transcription of both pachytene piRNA precursor transcripts and messenger RNAs encoding piRNA
282 gnificantly, in human iPSC-derived hemogenic precursors, transient inflammasome stimulation increased
283 clease that uses its PPR domain to recognize precursor tRNAs (pre-tRNAs) as it catalyzes removal of t
285 e show that depletion of the hyaluronic acid precursor UDP-glucuronic acid is sufficient to inhibit s
286 ) and mitigates the issues of batch-to-batch precursor variability, resulting in QDs averaging within
288 arylating agent from a bench-stable Bi(III) precursor via telescoped B-to-Bi transmetallation and ox
289 the entire mRNA sequence of the yolk protein precursor, vitellogenin, and monitored its transcript le
290 argon matrices by UV-irradiation of an azide precursor, was found to spontaneously cyclize to singlet
292 +) T cell families derived from single naive precursors, we find that fate decisions made during the
294 ia, cytokines, leukocytes, and hematopoietic precursors were quantified in blood, bone marrow, and or
295 a further group of patients, the uncommitted precursors were unable to support the constant developme
296 onfers crystallinity to these cyclopropanone precursors, were found to have a crucial impact on the r
297 was synthesized by reaction of the phenolic precursor with (11)C-methyl iodide, giving a radiochemic
298 revented by using the uncleaved gp160(JR-FL) precursor with alterations in the protease cleavage site
300 Machine (SVM) that identifies candidate RiPP precursors with pan-genomic analyses to identify which o