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1 >=65 years) and glycemic status (diabetes or prediabetes).
2 lanzapine, were overweight or obese, and had prediabetes.
3 n patients with HFrEF and type 2 diabetes or prediabetes.
4 ion and management of diabetes with focus on prediabetes.
5 d with greater IR and a higher likelihood of prediabetes.
6 ffecting multiple organs in individuals with prediabetes.
7 atio was also increased in these donors with prediabetes.
8 networks are affected in type 2 diabetes and prediabetes.
9 was attributable mainly to individuals with prediabetes.
10 rough compensation of insulin resistance, to prediabetes.
11 ldren with NAFLD also had type 2 diabetes or prediabetes.
12 ith overall diet quality in individuals with prediabetes.
13 parable among smokers and never-smokers with prediabetes.
14 .5% of the patients were women and 61.2% had prediabetes.
15 ection fraction <=40% and type 2 diabetes or prediabetes.
16 in UWS of patients with CP with and without prediabetes.
17 levated in patients with CP with and without prediabetes.
18 nd marginal bone loss (MBL) in patients with prediabetes.
19 have not specifically examined subsets with prediabetes.
20 ations, especially in those individuals with prediabetes.
21 flammatory conditions with gutka chewing and prediabetes.
22 individuals with prediabetes and 44 without prediabetes.
23 une T1D, whereas nondiabetic BBDP rats mimic prediabetes.
24 n in subjects with type 2 diabetes (T2D) and prediabetes.
25 er study involving 12 obese individuals with prediabetes.
26 dults with normal glucose tolerance and with prediabetes.
27 articipants with normal glucose tolerance or prediabetes.
28 ertain deleterious metabolic consequences of prediabetes.
29 nths, 13 (37%) had diabetes and 15 (43%) had prediabetes.
30 ticipants had diabetes, whereas 11 (42%) had prediabetes.
31 undiagnosed diabetes mellitus and 37.5% had prediabetes.
32 of diabetes in individuals with obesity and prediabetes.
33 ogression of early-stage type 2 diabetes and prediabetes.
35 (2.3%, 95% CI 0.4 to 4.2) than in those with prediabetes (1.2%, 0.0 to 2.4) or normoglycaemia (1.2%,
37 omen; 45 with normoglycemia [44.1%], 31 with prediabetes [30.4%], and 26 with type 2 diabetes [25.5%]
38 fetime risk was 48.7% (95% CI 46.2-51.3) for prediabetes, 31.3% (29.3-33.3) for diabetes, and 9.1% (7
40 e with type 2 diabetes (43.2%) compared with prediabetes (34.2%) or normal glucose (22%) (P < .001).
41 ls to define undiagnosed diabetes (>/=6.5%); prediabetes (5.7% to 6.4%); and, among persons with diag
42 ) for central obesity, 30.5% (30.0-31.0) for prediabetes, 5.1% (4.9-5.3) for diabetes, 16.3% (15.9-16
43 indexes, were similar across groups: 69% had prediabetes, 54% had hypertension (47% were taking antih
45 nd Jan 1, 2012), 1148 participants developed prediabetes, 828 developed diabetes, and 237 started ins
46 nts with diabetes (16.4%) than in those with prediabetes (9.2%) or normoglycaemia (8.5%); hazard rati
47 c level was above guideline levels for DM or prediabetes according to the American Diabetes Associati
48 een peripheral hyperinsulinemia, as found in prediabetes, age-related neurodegeneration and cognitive
50 identify individuals with undiagnosed DM or prediabetes among patients attending a dental setting fo
52 iabetes, and 38.0% (95% CI, 34.7%-41.3%) for prediabetes; among those with diabetes, 36.4% (95% CI, 3
53 re 0.97 (95% CI 0.87-1.09) for patients with prediabetes and 1.30 (95% CI 0.93-1.81) for those with n
54 ed hs-cTnT were 1.40 (95% CI, 1.08-1.80) for prediabetes and 2.47 (95% CI, 1.78-3.43) for diabetes me
55 fined using HbA1c values (29.2% vs 48.6% for prediabetes and 3.8% vs 7.3% for diabetes in 572 observa
58 CI, 1.04-2.40) times greater odds of having prediabetes and 5.0 (95% CI, 2.49-9.98) times greater od
62 blind, placebo-controlled trial, adults with prediabetes and a body-mass index of at least 30 kg/m(2)
64 imulated whole saliva (UWS) of patients with prediabetes and chronic periodontitis (CP) remains uninv
65 (USPSTF) recommended targeted screening for prediabetes and diabetes (dysglycemia) in adults who are
66 europathy is the most common complication of prediabetes and diabetes and presents as distal-to-proxi
67 uropathy progression and disease severity in prediabetes and diabetes correlates with dyslipidemia in
71 diastolic dysfunction among individuals with prediabetes and diabetes mellitus (versus diabetes melli
76 ic simulation was developed to replicate the prediabetes and diabetes trends (1997-2010) in the U.S.
78 ANCE STATEMENT There is a global epidemic of prediabetes and diabetes, disorders that represent a con
82 T2D-related traits: risk of T2D, presence of prediabetes and homeostatic model of assessment - insuli
84 interventions, possible misclassification of prediabetes and metformin use, and inability to define e
86 e (IR) and beta-cell function in people with prediabetes and suboptimal vitamin D status (<50 nmol/L)
87 le grain protects against the development of prediabetes and T2D and tested for modulation by polymor
88 NADPH levels were significantly degraded in prediabetes and T2D but were largely protected when mice
92 factors that are potentially manageable are prediabetes and the metabolic syndrome, neuropsychiatric
93 ncluding patients with diabetes mellitus and prediabetes and those with high risk of cardiovascular d
95 ss the associations of plasma magnesium with prediabetes and type 2 diabetes (T2D) among Chinese adul
97 icipants with diabetes, 47 participants with prediabetes, and 45 control participants underwent detai
100 hewing alone, chewing among individuals with prediabetes, and chewing among healthy controls did not
101 ars among persons with no diabetes mellitus, prediabetes, and diabetes mellitus were 3.7%, 6.4%, and
106 fects in Patients With Diabetes Mellitus, or Prediabetes, and Heart Failure]) to investigate the card
110 uxtamembrane epitopes, which appear early in prediabetes, and those to peptide 853-872 with Abs to an
112 munities Study with no diabetes mellitus, or prediabetes, and without cardiovascular disease includin
115 Moreover, a large number of people with prediabetes are at risk for developing frank diabetes wo
119 r fasting plasma glucose (FPG) >/=126 mg/dL, prediabetes as A1C 5.7%-<6.5% or FPG 100-<126 mg/dL, and
120 easures: The presence of type 2 diabetes and prediabetes as determined by American Diabetes Associati
121 en with NAFLD and assess type 2 diabetes and prediabetes as risk factors for nonalcoholic steatohepat
122 oping impaired glucose metabolism, including prediabetes, as are data for the risk of eventual progre
124 lp identification of individuals with DM and prediabetes at early stages of disease, which may preven
125 yses showed a lower arteriolar %-dilation in prediabetes (B=-0.20, 95% confidence interval -0.56 to 0
126 usted analyses showed a lower %-hyperemia in prediabetes (B=-46 [-163 to 72]) with further deteriorat
128 mRNA/protein) were higher in AT derived from prediabetes BB rats with destructed pancreatic beta-cell
130 h-fat diet (HFD) consumption caused not only prediabetes but also cognitive decline and brain patholo
131 progression from normal glucose tolerance to prediabetes by mechanisms likely tied to effects on insu
132 rms that individuals with undiagnosed DM and prediabetes can be identified in the dental office by ch
133 etabolic disease (ie, obesity, diabetes, and prediabetes) causes vascular dysfunction and is a risk f
134 tion of amylin is common in individuals with prediabetes, causes amylin deposition and proteotoxicity
140 diovascular outcomes and death compared with prediabetes defined with glucose-based definitions.
142 the risk of future outcomes across different prediabetes definitions based on fasting glucose concent
144 INTERPRETATION: Our results suggest that prediabetes definitions using HbA1c were more specific a
146 ity, hypertension, hypertension on 2 visits, prediabetes, diabetes, and high cholesterol than eczema
150 -Western vitamin D-deficient immigrants with prediabetes did not improve insulin sensitivity or beta
151 dontal inflammation than individuals without prediabetes even after controlling for sex and gutka che
153 A total of 130 non-Western immigrants with prediabetes (fasting glucose concentration >5.5 mmol/L o
154 at least two of three glycemic criteria for prediabetes (fasting plasma glucose level, 100 to 125 mg
155 o three groups: 1) group A: 75 patients with prediabetes (FBGLs = 100 to 125 mg/dL [HbA1c >/=5%]); 2)
156 he network measures of the participants with prediabetes fell between those with diabetes and control
158 ree groups: group 1: 28 patients with CP and prediabetes; group 2: 30 patients with CP and without pr
159 ting glucose (normoglycaemia: </=6.0 mmol/L; prediabetes: >6.0 mmol/L and <7.0 mmol/L; and diabetes >
161 aphic adjustment, HbA1c-based definitions of prediabetes had higher hazard ratios and better risk dis
165 glycaemia and diabetes risk in patients with prediabetes (HbA1c 5.7-6.4% [39-46 mmol/mol] or FPG 5.6-
166 was significantly greater among persons with prediabetes (HbA1c level of 5.7% to 6.4%) than among tho
167 led, 1856 (50%) had diabetes, 1268 (34%) had prediabetes (hemoglobin A1c [HbA1c] 5.7-6.4%), and 606 (
168 cose intolerance was defined as follows: (1) prediabetes: hemoglobin (HbA1c) >/=5.7 and <6.5% and (2)
171 confounders (race, body mass index, diabetes/prediabetes, hypertension), adjusted cumulative odd rati
172 red in 86% (95% CI, 72 to 100), remission of prediabetes in 76% (95% CI, 56 to 97), remission of elev
174 ermine the prevalence of type 2 diabetes and prediabetes in children with NAFLD and assess type 2 dia
175 erence analysis investigating the effects of prediabetes in coronary artery disease, stroke and chron
178 valence of undiagnosed diabetes mellitus and prediabetes in patients with community-acquired pneumoni
179 to determine incident diabetes and prevalent prediabetes in survivors of critical illness experiencin
180 Several measurements were used to test for prediabetes, including fasting plasma glucose, insulin r
182 s of different lifestyle interventions among prediabetes individuals and to identify the optimal age
183 ed mitochondrial capacity is associated with prediabetes, IR, and duration and severity of hyperglyce
184 ere significantly higher in individuals with prediabetes irrespective of gutka-chewing habit (P <0.05
186 hough the observational studies suggest that prediabetes is broadly associated with diabetes complica
188 Identification of individuals with DM and prediabetes is important to reduce DM-related complicati
189 the causal inference analysis revealed that prediabetes is only causally related with coronary arter
193 erm intervention study in 3234 subjects with prediabetes (mean+/-SD age, 64+/-10 years) that showed r
194 3%) male, 82 (78.1%) diabetes and 23 (21.9%) prediabetes, mean LV ejection fraction 32.5% (9.8%), and
195 a levels of selected miRNAs in subjects with prediabetes (n = 12), type 2 diabetes (T2D, n = 31), lat
196 rmal glucose tolerance (n = 740), those with prediabetes (n = 431), and those with confirmed type 2 d
197 th normal glucose tolerance (NGT) (n = 774), prediabetes (n = 525), or screen-detected type 2 diabete
198 (n = 5), 29% in the obese participants with prediabetes (n = 9), and 34.6% in the obese participants
200 classified into four groups: normoglycaemia, prediabetes, newly diagnosed diabetes, and known diabete
201 nonalcoholic fatty liver disease (NAFLD) and prediabetes (obese-NAFLD; n = 22).RESULTSInsulin sensiti
206 f intermediate hyperglycaemia (also known as prediabetes) on the basis of their ability to predict wh
207 e were estimated as the number of years from prediabetes onset and the average oral glucose tolerance
211 presence of pancreatic fat is not related to prediabetes or diabetes, which suggests that it has litt
214 iflozin did not lower HbA1c in patients with prediabetes or normoglycemia and was not associated with
216 enance sessions, risk level of participants (prediabetes or other), and intervention delivery personn
221 onse to an OGTT, and both men and women with prediabetes or type 2 diabetes had 16-21% lower 120-min
222 mpared with individuals with NGT, women with prediabetes or type 2 diabetes had 25% lower GLP-1 respo
223 s of nonalcoholic steatohepatitis (NASH) and prediabetes or type 2 diabetes mellitus (T2DM) seem to b
224 5.7% [39 mmol/mol]); (2) diagnosis codes for prediabetes or type 2 diabetes; or (3) antidiabetic medi
225 outcomes (hypertension, composite diabetes [prediabetes or type 2 diabetes], hyperlipidemia, cardiov
226 I-based; OR = 2.37, p = 0.001, waist-based), prediabetes (OR = 1.55, p = 0.02), diabetes (OR = 1.72,
227 NASH were significantly higher in those with prediabetes (OR, 1.9; 95% CI, 1.21-2.9) or type 2 diabet
229 s by glycaemic status at baseline (diabetes, prediabetes, or normoglycaemia)-defined on the basis of
231 s BP in individuals with insulin resistance, prediabetes, or other noncommunicable chronic diseases.
232 106 healthy individuals and individuals with prediabetes over approximately four years and performed
233 that beta-cell compensation associated with prediabetes overlaps with, and negates, its proliferativ
236 riglycerides (p = 0.015) and higher rates of prediabetes (p = 0.004), while LRRK2-NMC had higher trig
237 control analysis of 4447 867 newly diagnosed prediabetes patients, 1475 newly diagnosed T2D patients
238 on among patients with diabetes mellitus and prediabetes, patients at high risk of cardiovascular dis
241 le modification, irrespective of whether the prediabetes phenotype is defined by hyperglycaemia in th
248 anagement, people with diabetes mellitus and prediabetes remain at increased coronary heart disease r
255 with transient insulin resistance during the prediabetes stage and then underwent rapid beta-cell los
257 ars consistently reduced at the asymptomatic prediabetes stage, including in db/db mice, showing stro
259 s relationship in humans using data from the prediabetes study of the Integrated Human Microbiome Pro
261 o do so, we investigated the associations of prediabetes, T2DM, and measures of hyperglycemia with mi
264 function in glucose metabolism in youth with prediabetes, the relationship between adipose tissue ins
265 rs compared to non-chewers; in patients with prediabetes, the severity of periodontal inflammation is
269 ta for the risk of eventual progression from prediabetes to diabetes and for initiation of insulin tr
270 45 years, the lifetime risk to progress from prediabetes to diabetes was 74.0% (95% CI 67.6-80.5), an
271 imated the lifetime risk of progression from prediabetes to overt diabetes and from diabetes free of
273 e 3-year assessment of the SCALE Obesity and Prediabetes trial we aimed to evaluate the proportion of
274 glucose impairments, from normoglycaemia to prediabetes, type 2 diabetes, and eventual insulin use.
275 In conclusion, early in the development of prediabetes/type 2 diabetes in youth, ChREBPbeta express
276 We aimed to determine the prevalence of prediabetes, undiagnosed diabetes mellitus, and risk fac
278 mice, we modeled metabolic disease (obesity/prediabetes) via chronic high-fat (HF) diet and modeled
279 nic (445 of 675).The estimated prevalence of prediabetes was 23.4% (95% CI, 20.2%-26.6%), and the est
283 valence of undiagnosed diabetes mellitus and prediabetes was estimated based on hemoglobin A1c measur
285 G, or 2-hour PG definitions for diabetes and prediabetes) was 14.3% (95% CI, 12.2%-16.8%) for total d
286 etabolism.Among African-American adults with prediabetes, we conducted a double-blinded pilot randomi
287 ng associations between bacterial levels and prediabetes were as follows: A. actinomycetemcomitans, 2
292 periodontal inflammation in individuals with prediabetes were nine times higher than in healthy contr
293 portions of patients with undiagnosed DM and prediabetes were observed in the periodontitis group (32
297 al data from 2654 US adults with undiagnosed prediabetes who participated in the 2005-2010 NHANES cyc
298 evaluate the proportion of individuals with prediabetes who were diagnosed with type 2 diabetes.