ライフサイエンスコーパス: predispose

1 of obesity was steeper among the genetically predisposed.

2 pproaches taken were successful in revealing predisposing abnormalities in heterozygotes for GBA1 mut

3 Diabetes mellitus predisposes affected individuals to a significant spectr

4 ry cause of acquired long-QT syndrome, which predisposes affected individuals to ventricular arrhythm

5 bodyweight, tachycardia, and muscle wasting, predisposing affected individuals to substantial morbidi

6 ted increases in the memory Th17 compartment predispose aged mice toward the development of severe co

7 lustrate that GWAS-based searches for cancer predisposing allelic variants can be enhanced by includi

8 Matching could occur between predisposing and exciting causes in individuals who had

9 Ratings of predisposing and exciting causes were mandated in the Un

10 indicating pre-existing circuit function can predispose animals to differential fearful responses to

11 dicating enhanced internalization of sandman predisposes animals to seizures.

12 Significant predisposing associations were observed between the expo

13 ultiple domains of social determinants, that predispose Black individuals to disparate AKI risk after

14 docarditis (IE), particularly in people with predisposing cardiac valvular damage.

15 a hot spot for copy number variations, which predispose carriers to a range of neuropsychiatric pheno

16 en (>1% to 5%), fewer than 1% of genetically predisposed carriers will develop pB-ALL.

17 The 16p11.2 distal CNV predisposes carriers to e.g., autism spectrum disorder a

18 okine diffusion-driven degradation, and also predisposes cartilage for further biomechanical degradat

19 tary or constitutional factors were critical predisposing causes, but education, occupation, sex, and

20 hat TEVs promote malignant transformation of predisposed cells by inhibiting pro-apoptotic signals an

21 Genomic instability (GI) predisposes cells to malignant transformation, however t

22 by aberrant mitochondrial metabolism, which predisposes cells to oxidative stress and apoptosis.

23 nd (7) too many vaccines given early in life predisposing children to health and developmental proble

24 We hypothesize that HLA-A29 may predispose chorioretinitis via an altered gut microbiome

25 een described, but pre-existing factors that predispose clinically normal corneas to aberrant fibrosi

26 s with PML, each with a different underlying predisposing condition.

27 Despite no explicit whole-haplotype predisposing configurations being identified, all NAHR e

28 better understanding of the mechanisms that predispose dysmenorrheic women to BPS is needed to devel

29 crease appears to be less subtle for disease-predisposing environmental insults.

30 esophagus to the left atrial posterior wall predisposes esophagus to thermal injury during catheter

31 Hepatic ALR deficiency may be a critical predisposing factor for aggressive NAFLD progression.

32 Antibiotic-induced dysbiosis is a key predisposing factor for Clostridium difficile infections

33 y) has long been hypothesised to represent a predisposing factor for functional neurological disorder

34 ) as an agonist of Estrogen Receptors, known predisposing factor for hormone-driven breast cancer, wh

35 s and to concurrently address the underlying predisposing factor for the infections-opioid use disord

36 de polymorphism (SNP) represents a favorable predisposing factor leading to HHV-6A/B integration.

37 to S aureus colonization, a well-established predisposing factor to invasive S aureus disease.

38 Contact lens wear remained the most common predisposing factor, with Pseudomonas species as the maj

39 Multiple predisposing factors (for example, pre-existing cognitiv

40 laboratory features of ACS and to assess the predisposing factors and predictors of severity.

41 sulinemia, and inflammation, which are known predisposing factors for cancer.

42 articular, there was no history of cancer or predisposing factors for chronic liver disease.

43 We sought to identify genetic predisposing factors for immediate reactions to beta-lac

44 Taiwan, DM, eye trauma, and dry eye were key predisposing factors for microbial keratitis.

45 Secondary end points included predisposing factors for treatment response and safety o

46 Predisposing factors may be classified in environmental,

47 me (DS) owing to the coexistence of multiple predisposing factors related to its genetic abnormality,

48 In such cases, various predisposing factors should be considered, including ant

49 r at any time, particularly in patients with predisposing factors such as pseudoexfoliation, prior vi

50 Predisposing factors were identified in 87 of 118 patien

51 lected data for demographics, comorbidities, predisposing factors, all-cause mortality, antifungal us

52 can arise from the joint action of multiple predisposing factors, including rare high-penetrance mut

53 dentification of human leukocyte antigens as predisposing factors.

54 dietary intervention to identify individual predisposing features of weight loss in combination with

55 While genetic factors may predispose for autoimmunity, additional environmental tr

56 pture preclinical molecular alterations that predispose for incident HF.

57 interfere with normal brain development and predispose for later dysfunctions.

58 ting state of the catalyst-substrate complex predisposed for asymmetric chlorolactonization.

59 Of these, brachycephalic types were predisposed for eight disorders and were protected for t

60 Barrett's esophagus (BE) predisposes for the malignant condition of esophageal ad

61 y pathogenic variants (P/LP) in known cancer-predisposing genes (KCPG).

62 explanation points to the interplay between predisposing genes and environmental exposure.

63 the identification of alterations in cancer-predisposing genes facilitates gene-informed molecular d

64 s subjected to a genetic test with 80 cancer predisposing genes.

65 viduals with no mutations in the major known predisposing genes.

66 variants that share association signals with predisposing genetic risk variants for smoking, suggesti

67 We found that the predisposing germline mutation of the NF1 gene was frequ

68 brain tumors, were investigated to identify predisposing germline mutations.

69 WT families so that individuals harboring a predisposing germline variant can undergo surveillance,

70 ted and 1780 downregulated genes in the haze predisposed group revealed alterations in pathways assoc

71 Further work to identify other predisposing HLA and non-HLA loci is required.

72 disease(4), the respective roles of disease-predisposing HLA molecules, and of adaptive and innate i

73 tic of active coeliac disease, expresses the predisposing HLA-DQ8 molecule, and develops villous atro

74 a suggest that elevated basal FOXM1 activity predisposes HPV+ HNSCC to WEE1i-induced toxicity and pro

75 At the same time, the protection predisposes humans to CKD, an elegant example of balance

76 rway epithelium and further perpetuated by a predisposed immune system.

77 has been shown to modify brain circuitry to predispose individuals for future alcohol abuse.

78 , it is unclear whether genetic risk factors predispose individuals to autism as a result of modifica

79 oestrogen inhibits lung development and may predispose individuals to be vulnerable to lung disease

80 Recognition that germline mutations can predispose individuals to blood cancers, often presentin

81 a bone marrow failure syndrome that can also predispose individuals to cancer.

82 ium channel Nav1.5, and some beta3 mutations predispose individuals to cardiac arrhythmias.

83 h fat and simple sugar content-is thought to predispose individuals to inflammatory skin diseases suc

84 sistance in opportunistic pathogens that may predispose individuals to opportunistic infections.

85 er of genetic alterations or conditions that predispose individuals to the development of ALL and tre

86 that germline ELP1 loss-of-function variants predispose individuals to tumour development in combinat

87 The greater increase in BMI in genetically predisposed individuals over time was apparent after adj

88 The disease develops in genetically predisposed individuals with exposure to an as-yet unkno

89 gG4 antibodies may lead to FS in genetically predisposed individuals.

90 Dysregulation of AP activity predisposes individuals to diverse disorders such as age

91 creases long-term morbidity and mortality by predisposing infected persons to cirrhosis of the liver

92 gulation of the TOLLIP gene in IPF lungs may predispose injured lung epithelial cells to apoptosis an

93 h receptor-specific drug intake, genetically predisposed irregular 5-HT receptor density, or change i

94 tifactorial etiology, involving congenitally predisposed isthmic conditions, altered biomechanics, an

95 ts substantial alterations, which we suggest predisposes it to be more active at low temperature.

96 Discovery of predisposing loci for kidney function in CAD patients wa

97 ocks activation of the DNA damage machinery, predisposing lung cells to cancer development.

98 id antibody syndrome, or to addressing a new predisposing medical condition, as in malignancy.

99 aphics, socioeconomic status, comorbidities, predisposing medications, PCI indication, periprocedural

100 Finally, defects in Ndc80 turnover predispose meiotic cells to chromosome mis-segregation.

101 netheless, loss of E-cadherin alone does not predispose mice to mammary tumor development, indicating

102 Lack of prebiotic fiber predisposed mice to hypertension in the presence of a mi

103 sufficient to induce leukemia in genetically predisposed mice, even in the absence of infectious stim

104 cteria that promotes leukemia in genetically predisposed mice.

105 c expression of Snai1 in hematopoietic cells predisposes mice to AML development.

106 odontal homeostasis and that absence of DDR1 predisposes mice to periodontal breakdown.

107 expansion but arrests differentiation, which predisposes mice to the development of liver tumors.

108 nd pramlintide on Abeta pathogenesis and the predisposing molecular mechanism(s) behind the observed

109 ith a history of breast cancer and a genetic predisposing mutation.

110 It is associated with predisposing mutations in the Nodal and Hedgehog (HH) pa

111 hypothesized that increased levels of IL-27 predispose neonatal mice to more severe infection during

112 rahepatic cholestasis of pregnancy (ICP) can predispose offspring to metabolic disease in adulthood,

113 Moreover, maternal and paternal obesity predispose offspring to poor cognitive outcomes by epige

114 l exposure to diesel exhaust particles (DEP) predisposed offspring to allergic airway disease (AAD, m

115 negatively affects fetal development, which predisposes offspring to metabolic diseases.

116 rs BAT thermogenesis and energy expenditure, predisposing offspring to metabolic dysfunctions.

117 er, these data suggest that VEGF can acutely predispose otherwise normal hearts to atrial arrhythmias

118 a demonstrate that loss of CFTR function may predispose patients to experience depression and that th

119 tly with severe PACG, suggesting that it may predispose patients to more aggressive disease developme

120 CA1, BRCA2, PRSS1, and mismatch repair genes predispose patients to PDAC.

121 enesis is needed to define determinants that predispose patients to PML, a goal whose urgency is heig

122 avirus disease-2019 (COVID-19) is thought to predispose patients to thrombotic disease.

123 edications (corticosteroids) as factors that predispose patients with asthma to OSA.

124 e investigated whether a high level of suPAR predisposed patients to acute kidney injury in multiple

125 with cystic fibrosis (CF), a condition that predisposes patients to chronic lung infections.

126 Corneal neovascularization (NV) predisposes patients to compromised corneal transparency

127 which underlies hospital transmissions, and predisposes patients to subsequent infections.

128 nd Escherichia coli in the intestinal lumen, predisposing patients to bloodstream invasion and sepsis

129 srupts the generation of normal blood cells, predisposing patients to hemorrhage, anemia, and infecti

130 ever, the mechanisms involved in genetically predisposed penetrance are not well understood.

131 se disorder to be related to an interplay of predisposing personality traits (e.g., impulsivity), and

132 Multiple processes likely predispose plaques to superficial erosion, including exp

133 Bacterial mutations predisposing pneumococcus to causing meningitis, a more

134 nd (3) it interacts with vascular disease to predispose poor cognitive performance.

135 any one of the four antigenic types of DENV predispose populations to outbreaks, viral genetic deter

136 This lead to altered organogenesis and predisposed progeny to long-term metabolic defects in an

137 and synaptic connectivity might precede and predispose Purkinje cells to early neurodegeneration in

138 s' care, and potentially identify new cancer-predisposing risk alleles.

139 of thoracic aortic aneurysms to contrast key predisposing risk factors both in isolation and in combi

140 ement typically exacerbated in cases wherein predisposing risk factors co-exist.

141 t patients had a history of corneal edema or predisposing risk factors for corneal edema.

142 Whether these associations reflect shared predisposing risk factors or causal consequences of alco

143 metabolic pathways or nutrient availability predispose stem cells towards transformation remains unk

144 mordial marker of carcinogenesis in a cancer-predisposed strain of mice, as evidenced by clonal expan

145 .4 to 23.7, p < 0.0001) greater for the most predisposed tenth compared with the least predisposed te

146 men, the prevalence of obesity for the least predisposed tenth increased from 0.9% (95% confidence in

147 age, the prevalence of obesity for the least predisposed tenth increased from 1.1% (95% CI 0.7% to1.5

148 o 6.5% (95% CI 5.0% to 8.0%), while the most predisposed tenth increased from 14.2% (95% CI 12.6% to

149 o 7.6% (95% CI 6.0% to 9.2%), while the most predisposed tenth increased from 15.4% (95% CI 13.7% to

150 st predisposed tenth compared with the least predisposed tenth, defined using the GPS for BMI.

151 .6 to 15.6, p < 0.0001) greater for the most predisposed tenth.

152 ars to act as a biased signaling switch, may predispose the AT1R and certain other GPCRs (such as che

153 uring acute bronchoconstriction episodes may predispose the HFEV(1) group to catastrophic reductions

154 between diverse immune cell populations and predispose the host to immune abnormalities.

155 In addition, it can predispose the host to other diseases, such as malignanc

156 Such disruption can predispose the hybrids to abnormalities and disease that

157 Genetic mutations predispose the serine protease inhibitor alpha(1)-antitr

158 bone in vivo and whether DC inhibition alone predisposed the animals to osteonecrosis.

159 density functional theory (DFT) calculations predisposes the copper active site for the formation of

160 13 (CL13), result in immune dysfunction that predisposes the host to severe infections with unrelated

161 n) may be one of the potential elements that predisposes the infant to developing behavioural problem

162 ption of viral RNA in the human placenta and predisposes the mother to pre-eclampsia.

163 ic morphogenesis of the vertebrate trunk but predisposes the neural tube to convergence defects that

164 mes, the incidence of obesity is increasing, predisposing the population to a range of musculoskeleta

165 have identified dominant LRRK2 alleles that predispose their carriers to late-onset idiotypic Parkin

166 ibiting the critical molecular pathways that predispose their differentiation.

167 sts that the parents' nutritional status may predispose their offspring to lipotoxic cardiomyopathy.

168 ersistence of intravascular aged neutrophils predisposed them to thrombo-inflammation and death.

169 about having a mutation in their blood that predisposes them to develop a malignancy, but which is s

170 n females than in males, which theoretically predisposes them to SAS in large parts of their genome.

171 orms the end of the substrate binding cavity predisposes them to single amino acid substitutions that

172 are being duplicated in proliferating cells, predisposing them to tumorigenesis.

173 ess and abnormal aortic hemodynamic profiles predispose these patients to dilatation of the thoracic

174 t apes, creating architectures that nowadays predispose these regions to disease-associated genetic i

175 hat the increased SR load in atrial myocytes predisposes these cells to subcellular Ca waves that occ

176 on of granule neuron progenitors (GNPs), and predisposes these cells to tumorigenesis.

177 rotein concentration increases the costs and predisposes these methods for spontaneous protein aggreg

178 Although oncogenic mutations predispose tissue stem cells to tumor initiation, the ra

179 ) had a damaging mutation in a gene known to predispose (TNFRSF13B [n = 3]) or cause a CVID-like prim

180 he data establish that the TINF2 truncations predispose to a tumor syndrome.

181 in non-nicotine-mediated responses that may predispose to addiction-related behaviors.

182 llowing allo-SCT and that this dysbiosis can predispose to adverse clinical outcomes, especially incl

183 arthritis, and systemic lupus erythematosus predispose to atherosclerotic cardiovascular disease (AS

184 only represent an esthetic concern but also predispose to biofilm accumulation and subsequent initia

185 ent preexisting patient characteristics that predispose to both infection and limb loss.

186 t common modifiable and genetic risk factors predispose to both malignancies and cardiovascular disea

187 sential gene BRCA2/FANCD1, when monoallelic, predispose to breast and ovarian cancer, and when bialle

188 Heterozygous germline mutations in BRCA2 predispose to breast and ovarian cancer.

189 processed in normal cells, and whether they predispose to cancer-associated translocations.

190 icts that excessively long somatic telomeres predispose to cancer.

191 aimed to identify new genetic variants that predispose to cirrhosis, to test whether such variants,

192 tions are copy number variations (CNVs) that predispose to developmental neuropsychiatric disorders.

193 A better understanding of the factors that predispose to different allergic trajectories is needed.

194 Genetic variation can predispose to disease both through (i) monogenic risk va

195 denote a group of congenital conditions that predispose to disease of the thoracic aorta.

196 tically acquired mitochondrial DNA mutations predispose to elevated subchondral bone turnover and hyp

197 efits are not without risk: SGLT2 inhibitors predispose to euglycemic ketoacidosis in those with type

198 of function variants in TMC6, TMC8, and CIB1 predispose to EV.

199 Genetic factors and steatosis predispose to hepatocellular carcinoma (HCC) in patients

200 We conclude that HTLV-1/HBV coinfection may predispose to HTLV-1-associated malignant disease.

201 sociation studies and investigating how CNVs predispose to human diseases.

202 ty could be usefully divided into those that predispose to illness and those that excite onset.

203 anisms, and pharmacokinetic alterations that predispose to inadequate antimicrobial levels.

204 tion, and suggest that SHANK3 deficiency may predispose to intellectual disability and socio-communic

205 polygenic and that the genetic variants that predispose to left-handedness may underlie part of the a

206 rstanding how this individual difference may predispose to mental and physical disorders.

207 ctions between diet and host physiology that predispose to metabolic syndrome are incompletely unders

208 undescribed loci at which inherited variants predispose to mosaic chromosomal alterations that duplic

209 We hypothesize that genetic variations may predispose to neurodegeneration induced by those heavy m

210 s, acquired deficiency of BMP9 signaling can predispose to or exacerbate PH, providing a possible mec

211 anism can cause nutritional deficiencies and predispose to osteopenia, sarcopenia, and anemia.

212 positive tumors and genetic factors that may predispose to paclitaxel-induced peripheral neuropathy (

213 be described, the hereditary syndromes that predispose to PDAC will be reviewed, and the current rol

214 e derived state for human polymorphisms that predispose to recurrent copy number variants associated

215 partial DGS (pDGS), other risk factors could predispose to recurrent infections, autoimmunity, and al

216 rgery and alternate risk factors for RRD may predispose to RRD after intravitreal injection.

217 als may have primary immunodeficiencies that predispose to severe infections caused by severe acute r

218 tic C. difficile colonization is believed to predispose to subsequent C. difficile infection (CDI).

219 r Trp53 Our data show that mutations in NFE2 predispose to the acquisition of secondary changes promo

220 fork integrity, which, when compromised, may predispose to the development of early-onset breast canc

221 ion is a significant worldwide health issue, predispose to the development of liver cirrhosis and hep

222 g muscular mitral-aortic discontinuity could predispose to the development of outflow obstruction in

223 ics, bacterial pneumonias in donors strongly predispose to the fatal syndrome of primary graft dysfun

224 anti-inflammatory drug (NSAID) allergies may predispose to use of stronger pain medications and poten

225 ntifying kidney allograft recipients who are predisposed to acute rejection (AR) could allow for opti

226 arts, while some PV patients are genetically predisposed to an aggressive clinical course.

227 colonized germ-free BALB/c mice (genetically predisposed to asthma), only partially evident in outbre

228 oni anaemia, a disease in which patients are predisposed to cancer.

229 esult, metal complexes of phosphangulene are predisposed to cocrystallize with fullerenes, thereby yi

230 Here, we report that TALI (a) is predisposed to constitutively activate GPHR, (b) can by

231 family Lycaenidae appears to be particularly predisposed to cycad-feeding and several cycadivorous ly

232 ciated with lineages, some of which are more predisposed to developing antimicrobial resistance than

233 mportant for people who are more genetically predisposed to diabetes.

234 the mounting evidence that cancer cells are predisposed to ER stress and vulnerable to targeted inte

235 Species in certain Pooideae clades are predisposed to evolve annuality from perenniality, poten

236 s, due to their G-richness, are particularly predisposed to forming these structures and thus represe

237 We observed that whereas PrP(C) is predisposed to full glycosylation and is therefore refra

238 Additional right ventricular failure predisposed to futility (hazard ratio, 8.48 [95% CI, 1.8

239 HLA-DRB1*10:01 predisposed to immediate hypersensitivity reactions to p

240 duals with shorter respiratory events may be predisposed to increased ventilatory instability and/or

241 exchange between two states, one of which is predisposed to interact with its parent catalytic domain

242 Patients with long QT syndrome (LQTS) are predisposed to life-threatening arrhythmias.

243 eady-state conditions, FlgHrnr(-/-) mice are predisposed to mount an allergic contact dermatitis, esp

244 rom the TACSTD2(high) luminal cells are more predisposed to neuroendocrine differentiation along pass

245 TBT) throughout pregnancy and lactation were predisposed to obesity due to altered chromatin organiza

246 DC-deficient mice were predisposed to osteonecrosis following dental extraction

247 targeted microbiome modification in children predisposed to pB-ALL could become a successful preventi

248 ertain races/ethnicities may be biologically predisposed to poorer COVID-19 outcomes.

249 also suggested that low-ENL excreters may be predisposed to proinflammatory cellular events due to up

250 , these findings suggest that infants may be predisposed to respond to common features of lullabies f

251 As a result, foreign genes are predisposed to spurious transcription.

252 allow for a more quiescent lung that is less predisposed to symptoms and exacerbations.

253 dividuals with inactivating mutations may be predisposed to these effects.

254 In mice predisposed to Wnt- or Shh medulloblastoma, Ddx3x sensed

255 tal masculinisation programming window (MPW) predisposes to a TDS phenotype.

256 vailability in Fhf2 knockout (Fhf2(KO)) mice predisposes to abnormal excitability at the tissue level

257 tion and that increased allergen penetration predisposes to allergic sensitization.

258 Relative deficiency of PGE(2) predisposes to anaphylaxis in humans and mice, whereas P

259 e hypothesis that relative PGE(2) deficiency predisposes to anaphylaxis.

260 Malaria strongly predisposes to bacteremia, which is associated with sequ

261 causes up to 10% of early organ failure and predisposes to chronic rejection.

262 The proposed mechanism is that the mutation predisposes to conformational change in the expressed pr

263 Compromise of this complex interplay predisposes to development of chronic nonhealing wounds,

264 l infection within 100 days after transplant predisposes to development of noninfectious pulmonary co

265 Myocardial steatosis predisposes to diastolic dysfunction, a heart failure pr

266 ortant circulating proteinase inhibitors and predisposes to early-onset emphysema through a loss-of-f

267 Lynch syndrome (LS) predisposes to endometrial cancer (EC), colorectal cance

268 Variable SI predisposes to marked SI increases after stressful event

269 Maternal obesity predisposes to metabolic dysfunction in male and female

270 Deletion of Dicer1 plus p53 via WAP-Cre also predisposes to pineoblastoma, albeit with lower penetran

271 ochondrial DNA mutations in Polg(D275A) mice predisposes to the development of knee osteoarthritis.

272 n the citric acid cycle and loss of function predisposes to the development of phaeochromocytoma/para

273 Ischemia reperfusion injury (IRI) predisposes to the formation of donor-specific antibodie

274 , and thickened mesentery are all conditions predisposing to a conversion.

275 ank (n=5949), iSPAAR (Identification of SNPs Predisposing to Altered Acute Lung Injury Risk; n=882),

276 es in hip shape in early life play a role in predisposing to hip OA in later life remains to be deter

277 nd increased immune cell activation, thereby predisposing to infection-associated autoimmune cytopeni

278 terized by defective hematopoiesis and often predisposing to myelodysplastic syndrome (MDS) and acute

279 family member 2 (TM6SF2) is a genetic factor predisposing to nonalcoholic fatty liver disease.

280 s the most frequent site of genetic variants predisposing to nonsyndromic TOF, followed by FLT4.

281 ut may be associated with hypophosphataemia, predisposing to osteomalacia and fractures.

282 Limited data exist on anatomic factors predisposing to pacemaker dependency after TAVR.

283 riodontitis; reinforcing the genetic profile predisposing to periodontitis.

284 leukemic clonal hematopoiesis persistence in predisposing to second AML.

285 disease 2019 (COVID-19) and (2) risk factors predisposing to severe disease/mortality in the general

286 troke, which may reflect shared pathobiology predisposing to small vessel arteriopathy.

287 indicated that the score contained variants predisposing to these conditions.

288 l changes in dopamine-recipient neurons that predispose toward disease.

289 iod exposure influences brain development to predispose toward emergence of psychiatry-relevant behav

290 ive haplotype (P = 4.75 x 10(-5)), which may predispose toward increases in CGG number to the premuta

291 As a consequence, PAG1 deficiency predisposed toward allergic sensitization and increased

292 The immune states that predispose towards allergic sensitization and disease de

293 genes involved in tissue barrier fitness are predisposed towards inflammatory diseases, but most do n

294 favorable to retrotransposition, aneuploidy predisposes tumor cells to L1 insertions, and retrotrans

295 issue-specific immune cell composition might predispose tumors in certain tissue sites to be more or

296 WGS identified pathogenic cancer-predisposing variants in 16.2% of patients.

297 The time to detect inherited cancer predisposing variants in the population is affected by t

298 These findings point toward a predisposing vulnerability in the causation of addiction

299 onstitute pregnancy specific complotypes and predispose women to PE.

300 ing patient and disease characteristics that predispose young people with this condition to these out