ライフサイエンスコーパス: preemptive

1 and 44.4% (24/54) of these transplants were preemptive.

2 In all, 44% were preemptive.

3 Of 3606 transplants, 28% were preemptive, 38% followed pretransplant hemodialysis (HD)

4 han those deemed to be at low risk with both preemptive (73.3% vs 44.4%; odds ratio [OR], 3.44 [95% c

5 tanding the causes of instability and taking preemptive actions will facilitate the development of rM

6 r data support a hypothesis that a concerted preemptive activation of the pentose phosphate pathway,

7 is study was unable to provide evidence that preemptive administration of an echinocandin was effecti

8 m the out-groups, and retaliate by signaling preemptive aggressiveness, which may not be asymmetrical

9 ection at the surgical site, though not as a preemptive analgesic, has recently been demonstrated to

10 We compared outcomes of 3509 preemptive and 14,075 nonpreemptive second kidney transp

11 ecological invasion when combined effects of preemptive and interference competition govern interacti

12 Preemptive and multiple-organ transplants were excluded.

13 und in basiliximab-treated patients for both preemptive and prophylaxis therapy.

14 medicine refers to predictive, personalized, preemptive, and participatory medicine and was the inspi

15 Trials assessing preemptive anti-CMV therapy may be warranted.

16 formation by peptidylarginine inhibition or preemptive anti-histone IgG injection significantly redu

17 ukocyte antigen (HLA) antibodies (DSA) and a preemptive antibody-directed therapy protocol consisting

18 e-blind, placebo-controlled trial assessed a preemptive antifungal approach with micafungin (100 mg/d

19 invasive candidiasis, tests will facilitate preemptive antifungal strategies.

20 uide clinicians in the use of prophylaxis or preemptive antifungal therapy in high-risk patients.

21 It is unclear how a targeted prophylaxis/ preemptive antifungal therapy strategy impacts the incid

22 invasive candidiasis (IC) and candidates for preemptive antifungal therapy.

23 Use of preemptive antifungal treatment for 3 months may be asso

24 Preemptive antifungal treatment for 3 months was signifi

25 macrophage control of TMEV infection through preemptive antiviral nitric oxide production and antivir

26 Despite pretransplant lymphoid depletion, preemptive antiviral therapy and minimization of posttra

27 CMV was managed using preemptive antiviral therapy and no patient received ant

28 included reduction in immunosuppression and preemptive antiviral therapy, at the discretion of the a

29 patient with detectable viremia who received preemptive antiviral therapy, suggesting that the adapti

30 load was introduced in 1994 with adoption of preemptive antiviral therapy.

31 r the past decade, most centers have adopted preemptive antiviral treatment or prophylaxis strategies

32 Preemptive application of APRV blocked early drivers of

33 2) and 18.8% (22/117), respectively, for the preemptive approach (P = .04); however, this analysis in

34 was significant among patients followed by a preemptive approach (SHR, 1.46 [95% CI, 1.01-2.12]; P =

35 The preemptive approach analysis included patients all patie

36 eal-time PCR has become the most widely used preemptive approach for managing cytomegalovirus (CMV),

37 ients and emphasize the effectiveness of the preemptive approach for prevention of CMV syndrome and e

38 A preemptive approach for the management of patients at hi

39 d to develop forecasting tools toward a more preemptive approach to outbreak investigation.

40 Implementing a different and preemptive approach with a low risk profile may be very

41 HCV-viremic organs have included delayed and preemptive approaches.

42 atio, 242.96 [24.82]) and was prevented with preemptive APRV (mean [SE] PaO2/FIO2 ratio, 478.00 [41.3

43 tat cells lack the first-strike advantage of preemptive attackers.

44 n other transplant contexts, the efficacy of preemptive B cell depletion to modulate alloimmunity or

45 of age or older and nonpregnant adults in a preemptive campaign in Kinshasa.

46 A focus on preemptive cardiac regeneration in the pediatric setting

47 Yet, in practice both protective and preemptive changes in behavior come with costs.

48 s by simulating an individual-based model of preemptive competition.

49 date to simultaneous IAT during nonemergency preemptive completion pancreatectomy through the pancrea

50 in which surveillance can be intensified and preemptive control can be implemented during future outb

51 These results imply that controversial preemptive control measures may be unnecessary; instead,

52 re lacking regarding the long-term effect of preemptive conversion to everolimus from calcineurin inh

53 Herein, we propose a concept, preemptive coordination (PC), for targeting positively c

54 s helpful for defining prognosis and whether preemptive coronary intervention reduces the incidence o

55 We hypothesize that preemptive correction of a mutation in the fetal inner e

56 Similarly, in a xenograft model the preemptive cotreatment of lung tumor cells with an EGFR

57 ining short-course antiviral prophylaxis and preemptive cytomegalovirus (CMV) polymerase chain reacti

58 in the first 180 days after transplant with preemptive DDK (3.7% vs. 1.1%; P=0.03) and similar morta

59 ving a pancreas transplant (LDK/noP, n=289), preemptive DDK (n=112), and preemptive SPK transplantati

60 a trend toward increased risk of death with preemptive DDK compared with preemptive PALK (hazard rat

61 : LDK/noP=0.08; SPK=0.85) but was lower with preemptive DDK versus preemptive PALK (P=0.03).

62 spiratory depression dismissed, and vigorous preemptive deep sedation or anesthesia provided.

63 sue of the JCI, Kelishadi et al. report that preemptive deletion of B cells prior to heart transplant

64 We conclude therefore that efficient preemptive depletion of CD20+ B cells is effective in a

65 kR1/pikR2-based bacterial resistance and the preemptive development of drugs that can remain effectiv

66 Furthermore, preemptive dexamethasone treatment of DSS-challenged SAM

67 D (e.g. ideal-despotic distribution or ideal-preemptive distribution).

68 selection was most consistent with the ideal-preemptive distribution, as opposed to the ideal-free or

69 ear isodars, which suggests a 'despotic' or 'preemptive' distribution of individuals across habitats,

70 This form of preemptive donor apoptotic cell infusions has significan

71 ed Th2/Th1 phenotype, were administered as a preemptive donor lymphocyte infusion at day 14 post-HCT.

72 Prophylactic or preemptive donor lymphocyte infusion may be useful, but

73 Furthermore, they suggest that preemptive elimination of CD59-overexpressing subpopulat

74 Preemptive erythropoietin might blunt the benefit of RBV

75 eserve announcements were to trigger similar preemptive fishing, this could temporarily increase the

76 f CM was 21.4% (95% CI, 11.6%-34.4%) without preemptive fluconazole and 5.7% (95% CI, 3.0%-9.7%) with

77 tscreening lumbar puncture before initiating preemptive fluconazole at 800 mg/d further reduced the i

78 with subclinical cryptococcal meningitis and preemptive fluconazole for those without meningitis.

79 coccal antigen (CrAg) screening and targeted preemptive fluconazole in antiretroviral-naive human imm

80 antigen (CrAg) screening and treatment with preemptive fluconazole reduces the incidence of clinical

81 luconazole and 5.7% (95% CI, 3.0%-9.7%) with preemptive fluconazole therapy initiated at 800 mg/d.

82 Pre-ART CRAG screening with preemptive fluconazole treatment and improved CM treatme

83 screening of individuals initiating ART and preemptive fluconazole treatment of CrAg-positive patien

84 ylactic group (8%) compared with none in the preemptive group (0%) died with a functioning graft, P=0

85 year acute rejection rate was lowest for the preemptive group (36%) compared with the HD (45.5%; P=0.

86 tients in each group, and one patient in the preemptive group developed CMV disease.

87 Thirty-seven percent of patients in the preemptive group developed CMV DNAemia, 68% of these pat

88 oring costs were significantly higher in the preemptive group, whereas medication cost was significan

89 ed similarities between the prophylactic and preemptive groups.

90 Preemptive hematopoietic stem cell transplantation does

91 ress in FA patients, for whom the concept of preemptive HSCT is discussed.

92 This study compares efficacy of preemptive ibuprofen and dexamethasone protocols for pai

93 Preemptive (ie, after remission) administration of ritux

94 influenza virus carrying the same mutation, preemptive immunization against these escape variants le

95 We have previously shown that preemptive infusion of apoptotic donor splenocytes treat

96 g an unprecedented shift toward large-scale, preemptive insecticide use: 34-44% of soybeans and 79-10

97 ecipients (P<0.001) and was less frequent in preemptive kidney graft recipients (P=0.002).

98 Five years after HSCT, he received a preemptive kidney transplant from his father.

99 ansplantation hypophosphatemia were lower in preemptive kidney transplant recipients than in patients

100 by specific treatment modality (dialysis or preemptive kidney transplant).

101 lysis earlier and were less likely to have a preemptive kidney transplant, while the timing and propo

102 essed slowly to CKD, which was followed by a preemptive kidney transplant.

103 Preemptive kidney transplantation (preKT) is associated

104 re was a slight increase in the frequency of preemptive kidney transplantation at ESRD onset, but kid

105 Preemptive kidney transplantation is the optimal treatme

106 tional Kidney Foundation CKD stage 4 or 5 or preemptive kidney transplantation, were identified using

107 ney failure, defined as need for dialysis or preemptive kidney transplantation.

108 Twenty-four patients underwent preemptive KTX and 69 received a living-donor KTX.

109 time of kidney transplant) of pancreas after preemptive LDK (PALK, n=389), preemptive LDK not receivi

110 pancreas after preemptive LDK (PALK, n=389), preemptive LDK not receiving a pancreas transplant (LDK/

111 subsequently transplanted), and 1 received a preemptive live donor KT without listing or ever receivi

112 9m)Tc-DMSA) renal scintigraphy in 2 cases of preemptive LKT demonstrated preserved native kidney resi

113 A preemptive management approach to patients at high risk

114 interventions may improve the prevention or preemptive management of this life-threatening infection

115 Finally, preemptive management strategies are outlined in certain

116 iviral therapy, and that evidence concerning preemptive management with CMVIG is limited, but promisi

117 als cannot eradicate the disease without the preemptive measures of the sick individuals.

118 Sick individuals may utilize preemptive measures to avoid spreading a disease.

119 Preemptive measures to prevent potential invasive specie

120 ft rejection and provides an opportunity for preemptive monitoring and treatment.

121 ll cost of (1) universal prophylaxis and (2) preemptive monitoring are similar, universal prophylaxis

122 laces the cost burden on the patient whereas preemptive monitoring shifts the cost burden to the heal

123 menting, as standard of care, an abbreviated preemptive monitoring strategy compared with universal p

124 ry 2007 and December 2007 were enrolled in a preemptive monitoring strategy that included no anti-CMV

125 institutional approach to MRD monitoring for preemptive MRD-triggered intervention, using patient sce

126 During a 2015 preemptive OCV campaign among internally displaced perso

127 gher policy stance favoring the retention of preemptive oil and gas statutes.

128 CMI risk, were randomized to receive either preemptive or 3-month antiviral prophylaxis.

129 The resulting reduced costs allow preemptive or compensated coercion to be an instantaneou

130 r secondary prophylaxis and diagnostic-based preemptive or empiric therapy.

131 Both prophylactic and preemptive oral valganciclovir therapy are effective for

132 rent study was to compare recent outcomes of preemptive (P) versus nonpreemptive (NP) living donor ki

133 lar between groups (83% prophylactic vs. 81% preemptive, P=0.754).

134 k of death with preemptive DDK compared with preemptive PALK (hazard ratio: 1.91; 95% confidence inte

135 85) but was lower with preemptive DDK versus preemptive PALK (P=0.03).

136 0.0001), with the highest incidence in D+/R+ preemptive patients (53.8% vs. 15.6%, P<0.0001).

137 450 mg oral valganciclovir/day for 100 days; preemptive patients were monitored by CMV-polymerase cha

138 Preemptive pharmacologic inhibition of Tgf-beta signals

139 sponse to influenza virus infection and that preemptive priming of CD4 T cell help can promote effect

140 D risk in F-->M HCT patients and may support preemptive prophylaxis therapy for cGVHD beginning at 3

141 gh the translocon complex are subjected to a preemptive quality control (pQC) pathway and are degrade

142 P(Sc), via ER stress and the activation of a preemptive quality control process, to neurodegeneration

143 Seventy-eight patients receiving preemptive R between January 2005 and January 2010 were

144 e infections and immune reconstitution after preemptive R treatment of EBV infection.

145 Preemptive re-treatment decisions can be individualized

146 Preemptive recipients had less acute rejection (12% vs.

147 of death-censored graft loss was observed in preemptive recipients when first transplant survival was

148 Moreover, preemptive reduction in immunosuppression is most effect

149 of up to 1% of each adulterant, allowing the preemptive rejection of suspect samples.

150 itourinary tract may allow for a planned and preemptive renal transplant, thus avoiding dialysis.

151 l of this study was to determine barriers to preemptive renal transplantation.

152 Adults receiving preemptive renal transplants have better allograft survi

153 or hemophilia, which is currently managed by preemptive replacement therapy.

154 This risks the possibility of preemptive resource extraction before the conservation i

155 re, we demonstrate that sleep loss amplifies preemptive responding in the amygdala and anterior insul

156 the platelet-dependent axis has evolved as a preemptive response to local stress, priming the body ag

157 nt consisting of return to dialysis therapy, preemptive retransplantation, or death with function).

158 aft failure (ie, return to chronic dialysis, preemptive retransplantation, or death) in individuals w

159 he first allograft, with 10 of 31 undergoing preemptive retransplantation.

160 Alternative short-term approaches aimed at preemptive risk stratification and prevention are needed

161 S13 deficiency during remission, 30 received preemptive rituximab (group 1); the other 18 did not (gr

162 Preemptive rituximab (R) treatment decreases the inciden

163 ompare the relapse incidence with or without preemptive rituximab infusion.

164 TTP remission should prompt consideration of preemptive rituximab to prevent relapses.

165 ed donor kidney (DDK) transplantation in the preemptive setting are unknown.

166 Our data encourage evaluation of preemptive solitary liver transplantation early in the c

167 vs. 1.1%; P=0.03) and similar mortality with preemptive SPK (2.3%; P=0.07).

168 LDK/noP, n=289), preemptive DDK (n=112), and preemptive SPK transplantations (n=1402) were compared.

169 ne elevated LDL levels or low HDL levels and preemptive statin usage were associated with higher SVR

170 Prophylactic and preemptive strategies are used to prevent cytomegaloviru

171 Preemptive strategies should consider it for safety usag

172 ders and their institutions should implement preemptive strategies such as telehealth and aggressive

173 Recommendations address prophylactic and preemptive strategies to minimize PTLD development, incl

174 VGCV prophylactic and preemptive strategies were compared in renal transplant

175 d for antiviral therapy and refining current preemptive strategies.

176 atic viremia could help significantly refine preemptive strategies.

177 higher for the prophylactic compared to the preemptive strategy (OR = 6.21; 95% CI, 2.55-15.20; P <

178 ograms used universal prophylaxis (UP), 8.7% preemptive strategy (PE), and 52.2% hybrid strategy.

179 ffects (leukopenia and neutropenia) than the preemptive strategy.

180 more frequent with prophylaxis than with the preemptive strategy.

181 The success of this preemptive strike implies a central role for B cells in

182 r preparing second generation analogues as a preemptive strike to such resistance strategies.

183 urther de novo sfRNA synthesis could form a "preemptive strike" strategy against DENV.

184 This preemptive study will aid in the interpretation of resis

185 ia in Plasmodium falciparum, which calls for preemptive surveillance of the African parasite populati

186 ive result(s) occurred in tests performed as preemptive surveillance only.

187 close proximity to the carbocation and cause preemptive termination through elimination.

188 ble type B dissection with suitable anatomy, preemptive TEVAR should be considered to improve late ou

189 tionally, hAAT treatment may be considered a preemptive therapeutic measure for individuals who are a

190 allenges remain for defining indications for preemptive therapies and integrating novel and conventio

191 was significantly higher in recipients under preemptive therapy (38.7% vs. 11.0%, P<0.0001), with the

192 An alternate approach, preemptive therapy (initiation of antiviral therapy for

193 ediate (D+/R+) CMV risk (n = 82) compared to preemptive therapy (n = 47) had no significant effect on

194 The differential impact of preemptive therapy (PET) and antiviral prophylaxis (AP)

195 tudy population consisted of patients in the preemptive therapy (PET) arm of a randomized, controlled

196 The relative costs of preemptive therapy (PET) or prophylaxis for the preventi

197 LT recipients managed with ganciclovir-based preemptive therapy (PET).

198 tients were randomized 1:1 to receive either preemptive therapy (valganciclovir, 900 mg, twice daily

199 D+/R+ recipients with preemptive therapy also had the highest rate of CMV dise

200 hylactic agents, and further improvements in preemptive therapy and treatment of established CMV dise

201 A preemptive therapy approach deserves further study.

202 Prophylaxis and preemptive therapy are attractive strategies for this se

203 vs. 30.1 +/- 4.7 mL/min per 1.73 m(2) in the preemptive therapy cohort, P < 0.05).CMV replication was

204 ents who received transplants in the current preemptive therapy era (n = 233) showed only lymphopenia

205 mized controlled trial of prophylaxis versus preemptive therapy for CMV.

206 In contrast, preemptive therapy has the advantage of leading to lower

207 n (pp65) antigenemia (pp65emia) for starting preemptive therapy have not been well established.

208 cal trial to determine the clinical value of preemptive therapy in SMM.

209 economic merit of universal prophylaxis and preemptive therapy in the management of cytomegalovirus

210 ganciclovir recipients versus 21% of placebo-preemptive therapy recipients (treatment difference, -0.

211 Defining criteria for preemptive therapy remains a challenge.

212 used drugs and diagnostics, ways to optimize preemptive therapy strategies with quantitative polymera

213 A targeted prophylaxis/preemptive therapy strategy within the first-year posttr

214 of CMV disease was significantly lower with preemptive therapy than antiviral prophylaxis (9% [9/100

215 countries using no CMV prevention, and more preemptive therapy used in Asia.

216 e mortality at last follow-up was 15% in the preemptive therapy vs 19% in the antiviral prophylaxis g

217 o 12%]) did not differ significantly for the preemptive therapy vs antiviral prophylaxis group, respe

218 D PARTICIPANTS: Randomized clinical trial of preemptive therapy vs antiviral prophylaxis in 205 CMV-s

219 MV infection under universal prophylaxis and preemptive therapy was determined among 653 R+ patients

220 Thus, universal prophylaxis dominates over preemptive therapy with a cost saving of $27,967 for 1 Q

221 were allowed to break the blind and receive preemptive therapy with caspofungin.

222 ad discontinued LET prophylaxis and received preemptive therapy with ganciclovir.

223 of EBV/PTLD as well as being used to inform preemptive therapy with reduction of immunosuppression,

224 Two patients received preemptive therapy with valganciclovir for individual ep

225 ctomannan (GM) received targeted prophylaxis/preemptive therapy within the first-year posttransplant.

226 Using a risk threshold of 50%, preemptive therapy would have been prescribed for 8.4% o

227 e [D-/R+]; 146 receiving prophylaxis and 150 preemptive therapy).

228 oidentical (haplo)-HSCT recipients receiving preemptive therapy, among whom the rate was 14.5%.

229 % using only universal prophylaxis, 21% only preemptive therapy, and 33% a hybrid combination depende

230 ipients with seropositive donors, the use of preemptive therapy, compared with antiviral prophylaxis,

231 ter transplant for universal prophylaxis and preemptive therapy, respectively.

232 Compared with preemptive therapy, universal prophylaxis incurred $1464

233 mpared with polymerase chain reaction-guided preemptive therapy.

234 .74; P = .003; Q = 48.10; I(2) = 75.1%) than preemptive therapy.

235 patients deserves investigation of BG-driven preemptive therapy.

236 prevention can be achieved by prophylaxis or preemptive therapy.

237 trials to evaluate the role of risk directed/preemptive therapy.

238 biweekly monitoring with a serum CMV PCR for preemptive therapy.

239 for early detection and prompt initiation of preemptive therapy.

240 egies for CMV prevention are prophylaxis and preemptive therapy.

241 revent CMV include universal prophylaxis and preemptive therapy; each has its merits, and will be com

242 study aimed to further validate the role of preemptive TIPS in a large number of high-risk patients.

243 of vasopressor medications, and avoidance of preemptive transfusions of fresh frozen plasma.

244 A preemptive transjugular intrahepatic portosystemic shunt

245 mong 8,053 patients, 1117 (13.9%) received a preemptive transplant (66.9% from LD, 33.1% from DD).

246 own how race/ethnicity and poverty influence preemptive transplant access in pediatric.

247 T1DM population, short-term mortality after preemptive transplant is similar between LDK and SPK.

248 ) have been performed selectively to offer a preemptive transplant option for simultaneous pancreas-k

249 irst posttransplantation month were lower in preemptive transplant recipients than in patients on dia

250 58 on dialysis before transplantation and 14 preemptive transplant recipients) at baseline, on day 15

251 Future efforts to promote equity in preemptive transplant should address the critical issues

252 Blacks were 22% less likely to receive a DD preemptive transplant versus whites (RR = 0.78, 95% CI:

253 % CI: 0.35-0.67) less likely to receive a LD preemptive transplant versus whites.

254 Adjusted risk ratios for preemptive transplant were calculated using multivariabl

255 nt racial/ethnic disparities in access to LD preemptive transplant where blacks were 66% (RR = 0.34;

256 oved survival (P=0.08) among recipients of a preemptive transplant.

257 ) score could enable earlier and potentially preemptive transplantation (preKT).

258 incidence of living donor or deceased donor preemptive transplantation among all black, white, and H

259 Patient survival associated with preemptive transplantation among T1DM recipients was exc

260 Prior preemptive transplantation and graft loss after 5 years

261 the strong association between knowledge of preemptive transplantation and predialysis referral, thi

262 nety-one subjects (46%) had been informed of preemptive transplantation before referral, and 80 (41%)

263 ld be applied to patient education regarding preemptive transplantation early after the diagnosis of

264 g-term dialysis and, if possible, conducting preemptive transplantation may represent the best strate

265 Preemptive transplantation results in excellent patient

266 Benefits and risks of preemptive transplantation vary between primary and seco

267 Preemptive transplantation was associated with a lower m

268 Preemptive transplantation was beneficial when first tra

269 analysis, among other factors, knowledge of preemptive transplantation was highly associated (odds r

270 The benefits of preemptive transplantation were evident in all patients

271 Preemptive transplantation with an extended criteria or

272 ody mass index, creatinine level, donor age, preemptive transplantation, deceased donor, early reject

273 odies, cold ischemia time, living donor, and preemptive transplantation.

274 as patient education regarding the option of preemptive transplantation.

275 A center's proportion of preemptive transplants (odds ratio [OR], 0.83; per 5% in

276 ent discontinued the study drug and received preemptive treatment against CMV infection.

277 recommend CMV prophylaxis or screening with preemptive treatment for all high risk recipients.

278 r to development of fulminant meningitis and preemptive treatment for CrAg-positive persons are recom

279 the potential advantage of prophylactic over preemptive treatment in high-risk patients and highlight

280 ys to attenuate cardiac disease in elders by preemptive treatment of age-related defects, in contrast

281 f genetic disease will potentially allow for preemptive treatment of anticipated postnatal disease by

282 The safety and efficacy of maribavir for preemptive treatment of CMV infection in transplant reci

283 Preemptive treatment of mice with anti-IL-6R or anti-IL-

284 actors and effectiveness of culture-directed preemptive treatment were evaluated via a Cox-proportion

285 kinetics of viremia and toxicities following preemptive treatment with and brincidofovir in children

286 s suggest a unique therapeutic potential for preemptive treatment with anti-TNF antibody to prevent s

287 the above-mentioned signs and symptoms, and preemptive treatment with dexamethasone should be starte

288 Preemptive treatment with SCP1 also upregulated agrin, t

289 s, and the effectiveness of culture-directed preemptive treatment, are not well known.

290 Parasitemia was successfully managed with preemptive treatment.

291 strategies for prophylaxis, monitoring, and (preemptive) treatment of CMV.

292 ion for sensory consequences of movement and preemptive updating of spatial representations.

293 Our findings imply potential merits for preemptive use of nebulized antibiotics in order to redu

294 These results indicate that preemptive vaccine updates may improve influenza vaccine

295 cribe the first-ever use of tecovirimat as a preemptive vaccinia virus treatment strategy during indu

296 Graft loss occurred in 7 vs. 4 patients on preemptive versus prophylactic therapy (P>0.05).

297 years was similar in the two groups (53+/-23 preemptive vs. 52+/-20 ml/min nonpreemptive; P=0.37).

298 om starting dialysis to waitlisting and less preemptive waitlisting included Medicare insurance for p

299 ng in poverty, being a non-U.S. citizen (for preemptive waitlisting), Medicaid insurance, waitlisted

300 to their lower socioeconomic status and less preemptive waitlisting.