ライフサイエンスコーパス: preferential

1 mperature hydrothermal fluids, demonstrating preferential (26)Mg incorporation into the oceanic crust

2 -induced genes, including H3.3S31ph, provide preferential access to the transcription apparatus.

3 and cells but also, for the first time, the preferential accumulation of platinum in different blood

4 Preferential accumulation of visceral WAT is associated

5 istone chaperones function together to drive preferential acetylation of H3K56.

6 Such Ni sites show not only preferential acetylene pai-adsorption, but also enhanced

7 Thus, the preferential activation of a key alarmin pathway facilit

8 as their own control, malignant cells showed preferential activation of a subset of evolutionarily yo

9 , which have recently been attributed to the preferential activation of beta-arrestin over G proteins

10 f novel MOR "biased" agonists, which lead to preferential activation of G protein pathways over recep

11 ly differently affected by strain leading to preferential active sites formation.

12 This tumor-preferential activity enhances the CAF-reprogramming eff

13 gic neurons, suggesting the GABAergic neuron-preferential activity of the minimal e1m promoter.

14 DM4B is a lysine-specific demethylase with a preferential activity on H3K9 tri/di-methylation (H3K9me

15 ic distribution of haplotypes revealed their preferential adaptation to different temperature zones.

16 ) as a prototypical system, we show that the preferential adsorption of 2-NAT on the prism tips leads

17 We also determined that AAMPs had preferential adsorption on the mineral phase of dentin,

18 The results of solution (31)P NMR showed the preferential affinities of P1,3 and P2 phosphate functio

19 Furthermore, His(100) and Asp(171) were preferential affinity sites for Cu(II) and that Cys(163)

20 ermore, the C-terminal region of SSX confers preferential affinity to repressed, H2AK119Ub-marked nuc

21 The main limitation of this technology is a preferential amplification of an allele and strand in th

22 earrangements, copy number alterations, with preferential amplification of CCNE1 (cells with this gen

23 bly, transcriptional CDK inhibition leads to preferential and concentration-dependent downregulation

24 that membrane deformations are associated to preferential arrangement of septin filaments on specific

25 Our model accounts for two biases: preferential ascertainment of severe cases and right-cen

26 FR and IFR, adjusted for right-censoring and preferential ascertainment of severe cases, are measures

27 Preferential association of Cic with dpERK serves two fu

28 ft in substrate specificity coupled with its preferential association of SHP2/T507K with Gab1 enable

29 had high association with immune cells, with preferential association with blood neutrophils relative

30 ibution arise through a Barabasi-Albert (BA) preferential attachment growth process, a fact that, alt

31 selected by each added site in the system, a preferential attachment network with degree distribution

32 gradients created by a curved surface drive preferential attachment to specific regions of the colle

33 one of two ways: using cumulative advantage (preferential attachment) choosing vertices in proportion

34 ich get richer rule (success breeds success, preferential attachment) while some others are assigned

35 Using a model based on geographical preferential attachment, we simulated the formation of a

36 Urban dynamism is fuelled by preferential attraction of young adults and not a fundam

37 cated that the canonical thymine base is the preferential base partner of methylated purine bases.

38 We conclude that the preferential binding of aPLs to phospholipid-bound beta(

39 oimmunoprecipitation experiments demonstrate preferential binding of both gephyrin and collybistin to

40 nscription factor binding analysis indicates preferential binding of DMRT2 to rs679482-A.

41 t SO(2) in wine is presented, exploiting the preferential binding of silver nanoparticles (AgNPs) wit

42 Our data show preferential binding of STAT5 and GATA1 to CNS-25 over t

43 actor binding domain are responsible for the preferential binding of UDP-GlcUA.

44 e SSIT without metal binding and reveals the preferential binding site in the CIP with K(+) counterio

45 In vitro, both tracers displayed preferential binding to activated hPBMCs.

46 to the human-type sialic acid receptor, with preferential binding to alpha2,6-linked sialic acids on

47 urface present in TgDelta185 facilitates its preferential binding to duplex DNA rather than RNA.

48 e-causing mutation within KIF1A that reduces preferential binding to GDP- versus GTP-rich microtubule

49 ion is caused by heterochromatin protein 1's preferential binding to histone H3 tails with a methylat

50 In response to acidosis, MondoA shows preferential binding to just two targets, TXNIP and its

51 drial transcription factor A (TFAM)) exhibit preferential binding to O(4)-nBudT-bearing DNA.

52 rdA enhances clockwise rotation involves its preferential binding to the clockwise state of FliG (Fli

53 AI binds to neutrophils and monocytes, with preferential binding to the proinflammatory monocyte sub

54 Our data demonstrate that state preferential binding, together with drug-binding kinetic

55 While early GC reactions supported preferential Bmem accumulation in the CNS, late GC react

56 han that of brittle oxide glasses due to the preferential breakage of the weak coordinative bonds (Zn

57 n made possible by techniques that allow the preferential capture and amplification of discrete genom

58 ss as conditionally essential under hypoxia, preferential carbohydrate metabolism including gluconeog

59 Rat F98 GBM cells demonstrated enhanced preferential cell invasion into oversulfated 3-dimension

60 ount for the context effects associated with preferential choice tasks.

61 tion of O(2) in the plasma and introducing a preferential "cleaning" step.

62 tained through a Szilard model entailing the preferential clearance of super-critical clusters.

63 Finally, our results indicate a switch from preferential cleavage of the pro-(R) to the pro-(S) carb

64 Bet v 1, affecting degradation kinetics and preferential cleavage sites of the endolysosomal proteas

65 Here, by taking advantage of the preferential colocalization of intravenously administere

66 iple nuclear RNA binding proteins, revealing preferential colocalization of subsets of factors.

67 Interestingly, preferential combinatorial binding by these transcriptio

68 Inertial effects do not result in preferential concentration, reducing the geometric colli

69 The results collectively indicate that preferential connectivity between functionally matched p

70 Preferential cortical responses to faces develop early i

71 The mathematical model predicted preferential CPP into cells with lower cell stiffness, e

72 This preferential Cu exchange appears to be driven by both th

73 Under long wavelength (visible) irradiation, preferential curing of acrylate components is observed.

74 onse to SAM depletion that is highlighted by preferential cytoplasmic and nuclear mono-methylation of

75 2 family genes is a key mechanism underlying preferential cytotoxicity induced by the SF3b-targeting

76 We have found that narciclasine displays preferential cytotoxicity towards PEL at low nanomolar c

77 F17464, a highly potent preferential D3 antagonist, is a novel compound in devel

78 Here we show that potent and preferential DDR1 inhibitors reduce neurotoxic protein l

79 ing enzymes in the kynurenine pathway caused preferential death of established colon cancer cells and

80 urodegenerative disease characterized by the preferential death of motor neurons.

81 an in the living plant tissues, indicating a preferential decomposition of (14) N-enriched organic co

82 Parkinson's disease is characterized by the preferential degeneration of dopaminergic neurons (DaNs)

83 hese results are well in line with early and preferential degeneration of striosome-rich striatal are

84 tic activity in vitro, promote the rapid and preferential degradation of CDK6 over CDK4 in Ph+ ALL ce

85 Preferential deletion of Shank3 in vS1 inhibitory intern

86 cleaved by specific RNases, leading to their preferential deletion.

87 ire when smoother surfaces may result in the preferential delivery of coarse material to channel netw

88 ain did not impair vesicular trafficking and preferential delivery of Na(v)1.6 to the AIS; nor was th

89 Preferential dendrite growth allows for heightened anima

90 f transcription factors (TFs) that drive the preferential, differential expression of individual memb

91 l abnormality can be inferred by mapping the preferential diffusion of water along cardiac muscle fib

92 owing cells leads to formation of areas with preferential direction of cell swimming.

93 These geometries define preferential directions of flow.

94 action decreases drastically, suggesting the preferential dissolution and the formation of more stabl

95 of the chemical gradients, in agreement with preferential dissolution of the crystallite core in acid

96 ntly enriched in specific subtypes reflected preferential dysregulation of additional pathways, such

97 logical well-being and there appears to be a preferential effect of vegetables (compared with fruit)

98 n psychological health (n = 3), 2 reported a preferential effect of vegetables (compared with fruit)

99 ide electroreduction, which is caused by the preferential electroreduction of nitrogen oxides over ca

100 We optimize for preferential encapsulation of single cells with extremel

101 ctive self-motion, which in turn enables the preferential encoding of unexpected motion to ensure pos

102 These preferential enhancements were repeatedly and reproducib

103 otypes adapted to desert environments with a preferential enrichment for members of Actinobacteria.

104 The preferential enrichment of (56)Fe in Planolites burrows

105 Pathway preferential estrogen-1 (PaPE-1), which targets ERalpha

106 We observe preferential evolutionary divergence in neuron subtype-s

107 ion of certain miRNA operons and may explain preferential evolutionary emergence of miRNA operons.

108 cose, which acts as a cryoprotectant through preferential exclusion from side chains of the protein.

109 ional ensemble, which is consistent with the preferential exclusion of cosolutes.

110 antities of CD4(+) T lymphocyte subsets with preferential expansion of CXCR3(+) CCR6(-) cells in TB-I

111 te alphabeta T cell development, albeit with preferential expansion of Trbv1-DJbeta2 rearrangements.

112 mal affinity to the relevant antigen undergo preferential expansion, is a key feature of adaptive imm

113 f the GPRIN3 gene in both populations with a preferential expression in indirect MSNs.

114 alysis revealed several genes, which display preferential expression in the glandular trichomes and t

115 Arm selection, the preferential expression of a 3' or 5' mature microRNA (m

116 ase is allele-specific expression (ASE), the preferential expression of one allele.

117 ferential interaction with other proteins to preferential expression or localization.

118 ependently of interindividual differences in preferential facial information sampling (e.g., eye vs m

119 species are typically short-lived, and their preferential fates depend on kinetic and compartmentaliz

120 Aerobic glycolysis, or preferential fermentation of glucose-derived pyruvate to

121 Finally, CLZ depth injection simulated preferential flow and demonstrated the importance of the

122 derived AEOs was detected within an inferred preferential flow-path, highlighting the potential for t

123 sting root systems increase the tendency for preferential flow.

124 d bladder dysfunction are the outcome of the preferential focus of the adaptive immune response on ep

125 his suggests that reinforcement occurs along preferential force directions, thus stabilizing those cy

126 n contrast, s-cis constrained dienes lead to preferential formation of (4 + 2) products by both stepw

127 nism, we provide the first evidence that the preferential formation of [M + H](+) ions with MALDI-2 h

128 ics studies of model loop peptides confirmed preferential formation of endo cycloadduct stereochemist

129 us charge solvation processes, including the preferential formation of helices that solvate charged l

130 olumnar junction (SCJ) epithelium results in preferential formation of metastatic poorly differentiat

131 below the critical temperature leads to the preferential formation of one chiral domain.

132 et oxygen sensitizer, as demonstrated in the preferential formation of the endoperoxide of dimethylan

133 ied a unique asymmetric design that exhibits preferential fragmentation of cross-links over peptide b

134 d downregulation of F5Hs are consistent with preferential funneling of 4CL5 products toward G-lignin

135 l, loss-averse decisions were accompanied by preferential gaze toward losses and increased pupil dila

136 Collectively, these data demonstrate preferential gene derepression and ERV reactivation in A

137 ce from CAST x FVB reciprocal crosses showed preferential gene expression from the maternal X compare

138 ly understood, as is the molecular basis for preferential glucuronidation by UGT1 and UGT2 family enz

139 of a single crystalline Li particle, with no preferential growth directions.

140 The molecular mechanisms determining myocyte preferential growth in width versus length remain poorly

141 HP1BP3 inhibition led to preferential growth inhibition of ALT cells, which was a

142 R-driven STAT3 overexpression as a driver of preferential growth.

143 ules with AuNP and MQ molecules with FeNP, a preferential HAT and PET process is eased.

144 Due to the preferential homing of AnxA5 to the TME enriched with PS

145 s the CCR9 chemokine receptor, which induces preferential homing of the engineered cells to the small

146 T cells from OT-I mice did not exhibit this preferential homing.

147 up/side-gradient areas (75%), likely due to preferential hydrophobic partitioning, electrostatic int

148 -2Ralpha expression, which facilitated their preferential IL-2-dependent expansion.

149 underlying neuronal processes explaining the preferential implication of the NAcC in deciding whether

150 underlying neuronal processes explaining the preferential implication of the NAcC in deciding whether

151 d tongue (natural sleep endoscopy) exhibit a preferential improvement in collapsibility (lowered crit

152 vidual brain network dynamics, we observed a preferential increase in neural synchronization patterns

153 Pamoic acid treatment results in a preferential increment of noninflammatory Ly-6C(Lo) mono

154 Thus, despite the preferential induction of apoptosis following exogenousl

155 cICB response is over fourfold greater, with preferential induction of mitosis- and interferon-relate

156 Thus, preferential infection by the virus is unlikely to cause

157 Therapeutic targeting of USP9X led to preferential inhibition of the ERG-dependent leukemias.

158 ial role of the histone variant H2A.Z in the preferential integration of Ty1/copia retrotransposons w

159 roscale Thermophoresis that also indicated a preferential interaction of PscN with secreted proteins

160 We found no evidence, however, of preferential interactions between Th1 cell-prone, high-a

161 the methyl-CpG-binding domain of MeCP2 shows preferential interactions with H3K27me3.

162 ALVC presents with a preferential involvement of the lateral and postero-late

163 pectroscopy validate the N-H(2) group as the preferential isotope exchange site.

164 coprotein and the TKI properties such as the preferential kinase conformation engaged and the spectru

165 can be either rationally designed to enable preferential labelling of cancer cells, or specifically

166 f RBM39 loss on splicing further resulted in preferential lethality of spliceosomal mutant AML, provi

167 lymerization strategy that uniquely utilizes preferential Lewis acid coordination to differentiate be

168 t the RBD positioning is very dynamic with a preferential localization near the membrane surface.

169 This method allows the precise preferential localization of fibers either at the interf

170 Preferential localization of NCLX to this domain allows

171 A prominent example is the preferential localization of the enzyme, glutamine synth

172 AP (A-kinase anchoring protein) binding with preferential localization of the holoenzyme to the lysos

173 ective receptor signaling is anchored on the preferential localization of the receptor in lipid rafts

174 dynamic reorganization processes lead to the preferential location of active sites within 12-MR pocke

175 hereas the nature of the tail determines the preferential location.

176 corneal graft, including VA, assessed by the preferential looking test and visual evoked potential.

177 Preferential looking was inferior to VA prediction by fo

178 Strand-specific telomere FISH indicates preferential loss of C-strand DNA while analysis of BrdU

179 This led to the preferential loss of expression of oncogenes involved in

180 tosidase (beta-Gal) activities, resulting in preferential loss of neutral sugars from cell wall polym

181 In literature, no segmental or preferential lymphatic drainage patterns are known to ex

182 ogether, these results show the existence of preferential lymphatic drainage patterns in the murine l

183 ta from blue dye liver lymphangiography show preferential lymphatic drainage patterns: Right lobe mai

184 yte membrane cholesterol levels modulate the preferential lysis of uninfected host cells by SLO, and

185 rther regulate dynamics within the CNS, with preferential maintenance of tdTomato(+) B cells in spina

186 However, mechanisms for preferential malignant transformation at the junction ar

187 innervated excitatory cortical targets in a preferential manner and with larger synaptic terminals,

188 wer in cord than maternal plasma, suggesting preferential maternal-fetal transfer of iron, folate, co

189 M2-like macrophages and had a propensity for preferential maturation toward M1-like macrophages that

190 that ATRAM inserts into cancer cells with a preferential membrane orientation, where the C-terminus

191 exists between mood disorders and SZ, with a preferential metabolism of kynurenine to the potentially

192 expression of TGLI1, but not GLI1, promoted preferential metastasis to the brain.

193 Our strategy is based on combining the preferential methylation of open chromatin regions by DN

194 eat sink effect of coronary flow, as well as preferential microwave coupling to myocardium and blood

195 possible role of lactose crystallization in preferential migration of triglycerides to particle surf

196 y, our in vitro experiments failed to show a preferential migration pattern along the rostrocaudal ax

197 r respective DNA-binding motifs and identify preferential motif arrangements that influence accessibi

198 Conversely, preferential non-amyloidogenic processing of APP at the

199 support to the explanations offered for the preferential nucleation of BCC over FCC in metallic allo

200 R2B/PSD-95/MAP1A pathway, may be a novel and preferential option to ameliorate alpha-syn-induced neur

201 hape, which has been attributed in part to a preferential orientation of mitotic spindles along the p

202 f T. urticae, where strains generally showed preferential oviposition away from the acaricides.

203 of iron complexes, which seems to indicate a preferential oxygen activation chemistry by this transit

204 ate that for the system under consideration, preferential partitioning and therefore effectiveness in

205 ristics of air-water two-phase interface and preferential paths in porous structures were simulated.

206 nalyzing multi-phase flow and predicting the preferential paths of immiscible fluids in porous struct

207 We observed preferential phenotypes among subsets of expanded clonot

208 to be prokinetic in nature, facilitating the preferential processing of physiological neural activity

209 e network of brain regions that directs such preferential processing.

210 Here we show that this process requires preferential production of a siderophore precursor, 2,3-

211 togenetic-assisted circuit mapping reveals a preferential projection from VMHvl(vGlut2) to lPAG(vGlut

212 corticobulbar neurons on the basis of their preferential projections to SpVO versus SpVIr.

213 is the case for excitation waves, where the preferential propagation of excitations along a link dep

214 n particular PMe(3), are unique in promoting preferential reaction of Ni(0) with aryl tosylates and o

215 loping mice, GABAergic neurons are transient preferential recipients of thalamic inputs and undergo a

216 onse, without skewing of the response toward preferential recognition of a single virus.IMPORTANCE Th

217 We observed preferential recombination in telomeric regions and redu

218 nsitivity, and may exaggerate homophily when preferential recruitment occurs.

219 uced smaller effector B cell responses, with preferential recruitment of high-affinity B cells.

220 erential activity and limits bias in case of preferential recruitment.

221 he efficiency of converting CO(2) due to the preferential reduction of SO(2).

222 study of the excited-state also revealed the preferential relaxation emissive pathways for the BTD de

223 granule pools and confirm earlier models of preferential release of younger granules.

224 pology that deviated from randomness showing preferential repair to local regions or exchange between

225 tions during replication stress (RS) and the preferential resolution of DNA topological stress ahead

226 gene analysis identified T-types exhibiting preferential responses to intruder males versus females

227 Thus, the preferential responsiveness of IECs to type III IFN in v

228 Two mechanisms have been raised for the preferential retention of HIV within Tfh CD4(+) T cells:

229 This suggests a preferential role for theta rhythm in interval timing.

230 of glyceollin synthesis genes, suggesting a preferential role in promoting glyceollin turnover and/o

231 Of note, the preferential role of GluN2A-NMDAR in homocysteine-induce

232 endering them sufficiently flexible to avoid preferential sample orientation concerns.

233 This substrate selectivity is based on preferential scaffolding of DCX, cdk5, and p35 by nestin

234 t timer protein, we aimed to investigate the preferential secretion model of insulin secretion and id

235 ed young and old insulin SGs, revealing that preferential secretion of younger granules occurs in glu

236 some arms into neocentromeres, causing their preferential segregation to egg cells in a process known

237 e the removal of diseased plants by roguing, preferential selection of planting material, deployment

238 ng Aire's expression and correlated with the preferential selection of proximal polyA sites by the 3'

239 of TCR sequence sharing, also implicating a preferential selection of shared cross-reactive CDR3beta

240 Preferential selection of the mutant splice site likely

241 vity and impact than mechanisms representing preferential selection or retention of more-productive s

242 ruvate antagonizes the effects of hypoxia on preferential self-renewal of SMSCs through dephosphoryla

243 Conversely, they observe preferential sensitivity of astrocytes to altered doses

244 nse to chemotherapy, as well as DFMO-induced preferential sensitization of TNBC cells to chemotherapy

245 nate affinities are decoupled because of the preferential sequestration of anions into solvating TMP

246 rite groups, this can only be explained by a preferential sequestration of Nb relative to Ta in a hid

247 ction, and also provides a mechanism for the preferential sequestration of the respiratory chain comp

248 nce, ATPs can thicken locally at GBs and the preferential site for twin thickening shifts from the mi

249 d assemblies identified 154 regions that are preferential sites of contig breaks, irrespective of seq

250 The preferential solvation of DMSO with Zn(2+) and strong H(

251 The FT-ICRMS data provided evidence of preferential sorption of specific HA fractions, primaril

252 o atomic-scale "smoothing" of the surface by preferential sublimation of the less stable sites.

253 We develop preferential subspace identification (PSID), which is an

254 one of the major phenolic compounds and the preferential substrate for polyphenoloxidase in apple ju

255 onation during microbial degradation and the preferential substrate utilization are the dominant mech

256 We find examples of preferential subtype recruitment with quantitative diffe

257 iarrhythmic mechanism has been attributed to preferential suppression of late sodium current (I (NaL)

258 We also find a preferential surface reconstruction of the polycrystalli

259 for alpha- and direction selective-RGCs and preferential survival of ipRGCs.

260 ns become more laterally dispersed and their preferential synapse development is impaired.

261 TGAX/CD11c, and CD83), but AD tissues showed preferential T(H)2 skewing (IL-13, CCL17/TARC, and CCL18

262 control, CD8(+) memory T cells, and induced preferential T-cell homing via modulation of vascular en

263 ms appear to work cooperatively due to their preferential targeting of specific cell wall assembly ma

264 beta7high memory CD4+ T cells are preferential targets during early HIV-1 infection, which

265 een applied to study mechanistic aspects and preferential targets of (1)O(2) in biological systems.

266 Still, it is unknown whether such preferential tracking also occurs in children whose spee

267 efined the center and periphery of AF driver preferential tracks and provided validated annotations f

268 0.57 at the harvest stage suggested that the preferential transformation of enantiomers varied at dif

269 We observed preferential translation of mRNAs with highly structured

270 th I-ribosomal subunits are required for the preferential translation of specific mRNAs, the Shine-Da

271 lar RNA-protein complexes contributes to the preferential translation of stress-responsive gene trans

272 This leads to preferential translation of transcripts with high initia

273 ypoxia-responsive gene transcripts and their preferential translation were generally accompanied by i

274 ranging from the remodeling of chromatin to preferential translation.

275 Meiotic drive is the preferential transmission of a particular allele during

276 The preferential transmission of alleles or genotypes is ter

277 ular approaches, we provide evidence for the preferential transport of AAV1 to postsynaptically conne

278 lectron microscopy analysis, arguing against preferential trimeric association of native MPER and TMD

279 tions in vitro and inside cells and displays preferential tropism for their progenitor cells.

280 g intensely investigated on account of their preferential tropism toward their parental cells.

281 The intrusion induces "preferential tropism" of roots by first generating a hum

282 K channels in MAs and eNOS in PAs, revealing preferential TRPV4(EC) -IK/SK channel coupling in MAs an

283 or Cy7) share an intriguing characteristic: preferential tumor accumulation and retention.

284 nd lagging-strand telomere replication shows preferential under-replication of lagging telomeres.

285 Luc and control uMUC1(low) ES-2 cells showed preferential uptake on the probe by the high expressor (

286 The conjugate showed preferential uptake toward the biotin-receptor-positive

287 regions (consistent with end resection), and preferential usage of microhomology-all signs of the alt

288 lence of a link strongly correlates with the preferential usage of the link in the direction of propa

289 Our results do not support the preferential use of BMS for patients with large coronary

290 These data support the preferential use of ceftolozane/tazobactam over polymyxi

291 were compared (preferential use with PPIs vs preferential use with H2RBs).

292 ulcer prophylaxis strategies were compared (preferential use with PPIs vs preferential use with H2RB

293 oma cells show higher oxygen consumption and preferential utilization of glutamine compared to radial

294 escribed in the literature but also suggests preferential utilization of key signaling pathways.

295 prediction of lifelong nutritional deficit, preferential VAT investment could contribute to abdomina

296 h support productive HIV-2 infection and are preferential viral targets in HIV-2-infected individuals

297 We speculate that after rupture, preferential volatilization of delta(15)N-depleted compo

298 representation and might be expected to show preferential weakness in ALS.

299 he split hand sign in ALS refers to observed preferential weakness of the lateral hand muscles, which

300 ome limitations of the NBATS tool, including preferential weighting based on current infrastructure.