ライフサイエンスコーパス: preparative

1 heptaprenol 4 in gram quantities will enable preparative access to key reagents for the study of the

2 Access to preparative amounts of discrete charged species allows f

3 o devise a procedure for the purification of preparative amounts of in vivo-synthesized apocatalase.

4 ising approach to quickly and easily produce preparative amounts of proteins.

5 lasma (NTP) is investigated as an innovative preparative analytical technique enabling classification

6 idered as the benchmark stationary phase for preparative and analytical chromatography.

7 or the integration of sample processing with preparative and analytical separations for biology and c

8 uch covalent modifications involve extensive preparative and post-preparative chemistry that poses da

9 e loaded catalyst are in line with a host of preparative and spectral data and with the structures of

10 free-floating products may be a general and preparative approach to access 2D nanomaterials.

11 bionanoparticles in vacuum is potentially a preparative approach to separate heterogeneous mixtures

12 Within this context, different preparative approaches for PDC-NCs as well as some of th

13 been investigated from both mechanistic and preparative aspects.

14 for applications ranging from analytical to preparative bioseparations.

15 A preparative biotransamination process has been developed

16 ound in the Athabasca oil sands region using preparative capillary gas chromatography (PCGC) followed

17 Preparative capillary gas chromatography (PCGC) is the c

18 n signature of C(ex) added from two sources: preparative capillary gas chromatography (PCGC, C(PCGC))

19 saccharides are one of the central goals of preparative carbohydrate chemistry.

20 e a cellular O-glycome preparation strategy, Preparative Cellular O-Glycome Reporter/Amplification (p

21 Preparative centrifugal partition chromatography (CPC) i

22 tions are widespread in nature, yet only one preparative chemical method addresses this challenge in

23 A combination of preparative chemistry and experimental results from NMR

24 e ligands, a widespread investigation on the preparative chemistry and properties of such compounds h

25 tions involve extensive preparative and post-preparative chemistry that poses daunting limitations in

26 tical when patients receive reduced doses of preparative chemotherapy and/or radiation compared with

27 anced follicular lymphoma by administering a preparative chemotherapy regimen followed by autologous

28 family history or newborn screening, use of preparative chemotherapy, or the type of donor used, did

29 mmunoglobulin were improved after the use of preparative chemotherapy, other immunologic reconstituti

30 e events were consistent with effects of the preparative chemotherapy.

31 00 iU/kg of interleukin-2 to tolerance after preparative chemotherapy.

32 yl-3-hydroxy-4-benzyloxy-5,6-epoxyazepane by preparative chiral HPLC and subsequent elaboration allow

33 Nitrile (+/-)-9 was resolved via preparative chiral HPLC to afford optically pure nitrile

34 This fraction was further purified by semi-preparative chromatography and characterised by HPLC-MS/

35 exoglycosidase digestion arrays, analytical/preparative chromatography and mass spectrometric detect

36 utical applications including analytical and preparative chromatography of organohalogenated species,

37 Preparative chromatography of peptides should preferenti

38 ial), including solvent partitioning through preparative chromatography, ranged from approximately 40

39 afforded diastereomers that were resolved by preparative chromatography.

40 f nanoliters and cannot be scaled up for the preparative collection of charge variants.

41 preparation is subsequently fractionated via preparative column chromatography using cellulose-based

42 We investigated whether preparative combination chemotherapy could replace TBI i

43 The potential for preparative concentration of DNA is demonstrated using a

44 sence of NK cells is a strong indicator that preparative conditioning is required for engraftment of

45 ansduced with the SIN-gammac vector, without preparative conditioning.

46 lamp and allows for analytical pulse flow or preparative continuous flow reactions.

47 with the low computed barriers, spectral and preparative data show that the reaction is not only poss

48 These studies illustrated the low preparative efficacy of biotransformations and the inabi

49 o our knowledge, migration assay with little preparative effort.

50 In preparative electrolysis experiments with a series of al

51 plored through a combination of voltammetry, preparative electrolysis, thiol-electrode modifications,

52 into fronting ones, significantly improving preparative enantiomeric separations.

53 Two preparative examples of cross metathesis with the macroc

54 tigram scalable, these transformations are a preparative expansion of the pinane family.

55 lations, and this mechanism was justified by preparative experiments carried out using NiCl(2)/bipyri

56 l chemistry, mass-spectrometric studies, and preparative experiments.

57 ution of chemically dissimilar components in preparative fractionations such as prep TREF (which norm

58 nd stearic (C(18:0)) fatty acids purified by preparative gas chromatography(5-8).

59 s to several analytical approaches including preparative gas chromatography, p-menth-1-en-3-one (pipe

60 n media can mimic the results obtained using preparative gas-phase FVP protocols.

61 With semi-preparative GPC the LMWDF (DP3) fractions in the wheat g

62 or either analytical (<50 microg protein) or preparative (>250 microg protein) applications.

63 r. dillenii fruits were fractionated by semi-preparative high-performance countercurrent chromatograp

64 Preparative high-performance liquid chromatographic (pre

65 tion of the amino acid hydroxyproline, using preparative high-performance liquid chromatography (Prep

66 PA photolysis products were isolated by semi-preparative high-performance liquid chromatography and i

67 for radiolabeling were obtained using chiral preparative high-performance liquid chromatography and u

68 hydrolysis, acetylation, and purification by preparative high-performance liquid chromatography, and

69 ary chromatographic techniques consisting of preparative high-speed countercurrent chromatography (HS

70 ding counter current chromatography and semi-preparative HPLC due to its low concentration and the pr

71 NHC-containing TM complexes were isolated by preparative HPLC on a chiral stationary phase in good yi

72 A two-stage preparative HPLC protocol was subsequently developed for

73 malic acid involved more than 20 steps and a preparative HPLC separation of diastereomeric intermedia

74 The combination of chiral preparative HPLC separation, VCD measurements, and theor

75 using SPE C-18 cartridges, purified by semi-preparative HPLC then analysed by HPLC/DAD/HRMS in both

76 g intermediates, subsequent fractionation by preparative HPLC, and final hydrogenation.

77 mic isomers, 4a and 4b, were separated using preparative HPLC, and structural analysis and self-aggre

78 The racemic mixture was separated by chiral preparative HPLC, and the resulting lead compound (3R,5S

79 ning all the detected flavonoids obtained by preparative HPLC, in terms of MICs for Staphylococcus au

80 Anthocyanins were isolated by semi-preparative HPLC, weighed, dried, and redissolved in aci

81 G by simple extraction technique followed by preparative HPLC.

82 lowing fractionation of methanol extracts by preparative HPLC.

83 omer was cleanly isolated without the aid of preparative HPLC.

84 alamondin peel was fractionated using a semi-preparative HPLC.

85 ola leaves and flowers were produced by semi-preparative HPLC.

86 diastereomers 7a-1, 7a-2, 7b-1, and 7b-2 by preparative HPLC.

87 ntrifugal partition chromatography (CPC) and preparative HPLC.

88 ere purified by liquid-liquid extraction and preparative HPLC.

89 IVTQTMK and VLVLDTDYK) were fractionated via preparative-HPLC and incubated with MDA at 37 degrees C

90 This work shows that a preparative IEF method using immobilized pH gradients ca

91 Therefore, preparative IEF methods are needed to fractionate charge

92 A variety of preparative IEF methods have been developed over the yea

93 Preparative immunoprecipitation demonstrated that EpCAM

94 ul tool for the rapid quantification and the preparative immunoseparation of the target proteins.

95 Owing to its tremendous preparative importance, rhodium carbene chemistry has be

96 omatographic fractionations of extracts from preparative incubations with the 2Z,6E substrate afforde

97 Here, we have evaluated a preparative irradiation-based method of liver repopulati

98 hemical solvolytic reactivity studied, using preparative irradiations, fluorescence measurements, nan

99 Preparative isolation of complex mixtures of compounds f

100 ossible, as well as those who seek advice on preparative issues, up to people having a certain applic

101 Using this approach, we demonstrate preparative labeling under mild conditions for up to ~16

102 ted and purified (>90%) by multi-dimensional preparative LC/MS fractionation.

103 Unlike previously described preparative LC/MS techniques, we have employed a dynamic

104 ncentration and fractionation of a sample by preparative Liquid Chromatography, identification experi

105 (87 wt.%) were successfully fractionated by preparative liquid chromatography.

106 ation of total body irradiation (TBI) to the preparative lymphodepleting chemotherapy regimen in sequ

107 s potential for increasing overall yields in preparative mass spectrometry is explored briefly.

108 By combining preparative mass spectrometry with scanning tunneling mi

109 ion to this problem, viz., a high-efficiency preparative method based on aerobic Co-/ N-hydroxysuccin

110 The best preparative method for producing bioactive peptides was

111 A preparative method for the synthesis of functionalized 2

112 e amount of included methanol depends on the preparative method used.

113 An efficient preparative method was developed for the synthesis of pr

114 As a preparative method, FVP is used mainly to induce intramo

115 ules and materials, and despite a variety of preparative methods being available, processes which int

116 Preparative methods for stable coatings on smooth substr

117 reports regio- and highly diastereoselective preparative methods for the synthesis of versatile alkal

118 However, to date, these preparative methods have typically been based on the dir

119 preparation of synthetic ultramarine, using preparative methods that would have been available to al

120 We show that preparative methods used previously in studying nucleoso

121 There were three preparative methods utilized for producing tempe-based p

122 A series of novel preparative methods were developed to address the proble

123 t will ultimately be determined by efficient preparative methods.

124 n describes structural features, utility and preparative methods.

125 cations in the development of analytical and preparative microfluidic protocols.

126 The reaction operates under preparative, operationally simple conditions (1 equiv of

127 o compartmentalize and access for integrated preparative or analytical operations on-chip.

128 ure a protein in a complex medium for either preparative or analytical use.

129 Recent progress in the preparative organic and organometallic chemistry of poly

130 ration procedures and evaluate the different preparative parameters, such as time of saponification,

131 ethyl ester (bis-[60]PCBM) isomer mixture by preparative peak-recycling, high-performance liquid chro

132 Preparative photo-oxidation experiments demonstrate that

133 Preparative photohydration and trapping reactions by thi

134 nd naphthyl phenols 5-8 were investigated by preparative photolyses in CH3CN-D2O, fluorescence spectr

135 photochemical reactivity was investigated by preparative photolyses, fluorescence spectroscopy, and l

136 y LFP, whereas the adducts were isolated via preparative photolyses.

137 Steady-state, preparative photooxidation experiments show that aryltri

138 fraction of bikunin GAG mixture obtained by preparative polyacrylamide gel electrophoresis, allowed

139 uired in order to take full advantage of the preparative potential of these transformations.

140 Key variables of the preparative process (e.g. chitosan and HA molecular weig

141 vetiver essential oil, was subjected to the preparative process, with the scope of isolating two low

142 A preparative protein alkaline hydrolysis procedure, as pa

143 A preparative protocol, based on the conversion into diast

144 cations ranging from metabolomic analysis to preparative purifications.

145 Using this approach, preparative quantities of hybrid and complex-type N-glyc

146 ly in expansion of the endosteal niche after preparative radioablation and in the engraftment of dono

147 ic route scouting to identify conditions for preparative reaction scale-up would be a transformative

148 Preparative reactions that occur efficiently under dilut

149 After a uniform preparative regimen (fludarabine 40 mg/m(2) x 5, cycloph

150 The present data show that the Pc 26.1 preparative regimen allows thalassemia patients to safel

151 ts the choice of bone marrow transplantation preparative regimen and can prevent morbidity.

152 Preparative regimen and HLH activity affected outcomes,

153 eceiving fludarabine/melphalan (FluMel) as a preparative regimen and patients with unrelated donors (

154 in a clinical setting after a myeloablative preparative regimen for stem cell transplantation, the t

155 The optimum preparative regimen for unrelated donor marrow transplan

156 n suggest its potential to become a standard preparative regimen in this population.

157 The preparative regimen included busulfan, cyclophosphamide,

158 lantation has been attempted with degrees of preparative regimen intensity, but graft rejection and g

159 Mice receiving a preparative regimen of nonmyeloablating (5 Gy) total bod

160 hout any statistically significance with the preparative regimen they received.

161 Total body irradiation-containing preparative regimen was the only variable favorably infl

162 Methods Patients received a lymphodepleting preparative regimen, followed by adoptive transfer of pu

163 oduction of novel antileukemia agents in the preparative regimen, maintenance of remission treatment

164 radiation and chemotherapeutic agents in the preparative regimen.

165 d donors, with the use of a nonmyeloablative preparative regimen.

166 ll children were given a fully myeloablative preparative regimen.

167 d a mouse model to investigate the effect of preparative regimens at primary BMT on outcome for secon

168 an increased risk for standard myeloablative preparative regimens based on age (>=50 years), an HSCT-

169 Further improvement of preparative regimens before allogeneic haemopoietic stem

170 ablative (or reduced intensity) conditioning preparative regimens before haemopoietic cell transplant

171 ummary, recipients of URD-PBSC HCT receiving preparative regimens differing in intensity experienced

172 e added to myeloblative and non-myeloblative preparative regimens for haemopoietic cell transplantati

173 usulfan with total body irradiation (TBI) in preparative regimens for hematopoietic transplantation a

174 in hematopoietic cell transplantation (HCT) preparative regimens for lymphoma.

175 Preparative regimens included myeloablative (MA; N = 611

176 tion of chemotherapy and radiotherapy in HCT preparative regimens is not feasible due to dose-limitin

177 hepatocyte transplantation after appropriate preparative regimens may permit sufficient repopulation

178 thymocyte globulin should be included in the preparative regimens of patients with haematological mal

179 nt-related mortality (TRM) were seen for all preparative regimens when CD34(+) cell doses exceeded 4.

180 an be safely combined with reduced-intensity preparative regimens with encouraging results in a singl

181 Results were similar using chemotherapy preparative regimens with or without addition of TBI.

182 Advances in preparative regimens, donor selection, and supportive ca

183 nts with contraindications to high-intensity preparative regimens, reduced intensity conditioning sho

184 Transplantation-preparative regimes were mostly cyclophosphamide with or

185 Their preparative relevance is underscored by an application t

186 Preparative remote methylene oxidation is obtained in 50

187 coupled cluster level of theory allowed the preparative results to be sorted and an intuitive model

188 on (SPE) using a C18 matrix followed by semi-preparative reverse phase-high performance liquid chroma

189 ion on Amberlite(R) XAD16 polyamide and semi-preparative reverse-phase HPLC columns.

190 We combined NMR spectroscopy, preparative reversed-phase (RP) chromatography, atomic f

191 A new preparative route was developed to synthesize new phosph

192 Herein we review the simplicity of the preparative routes available, and their influence over t

193 as the potential to provide more sustainable preparative routes to catalysts than the current multist

194 A classification of the preparative routes to these synthetic targets according

195 wed by a critical examination of the various preparative routes toward diazaphospholenes.

196 I and Id were separated by preparative RP-HPLC.

197 yst loadings as low as 0.01 mole percent and preparative scalability (25 grams) are demonstrated.

198 demonstrated by performing the reaction on a preparative scale (88 g).

199 formation of a key advanced intermediate on preparative scale absent any atropisomerization.

200 (I)-catalyzed addition can be conducted on a preparative scale and tolerates a broad substrate scope

201 To identify the oxidation products, preparative scale bulk electrolysis experiments were und

202 This monomer is easily prepared on a preparative scale by a catalytic, enantioselective appro

203 methyl jasmonate (MJ) were isolated at semi-preparative scale by HPLC, using a permethylated beta-cy

204 Here, methodology for the efficient, preparative scale construction of covalent TM complexes

205 ed with an enantiospecific acylase to give a preparative scale dynamic kinetic resolution which allow

206 uction of the Mn(I) center, as observed with preparative scale electrolysis and verified with (13)CO2

207 The preparative scale electrolysis generated epoxide-ring-op

208 activity is robust, and PikDH2 was used on a preparative scale for the chemoenzymatic synthesis of un

209 are highly effective; however, their use on preparative scale has minimal precedent because they req

210 ll as peel and fruit pulp were evaluated for preparative scale implementation.

211 sis of Au(102)(p-MBA)(44) nanoparticles on a preparative scale in high yield is described.

212 thod may also be useful to explore on a more preparative scale in the future.

213 te box", has been easily self-assembled on a preparative scale in water, using a template-assisted pr

214 e objective of this research is to implement preparative scale obtention of mangiferin and lupeol fro

215 Preparative scale peptide couplings of two N-Boc amino a

216 flavonoid scaffolds and provides a basis for preparative scale production of flavonoid 4 '-O-glucosid

217 A preparative scale reaction to deliver 25 g of product is

218 We also demonstrate preparative scale reductive aminations with wild-type an

219 e spent developing productive analytical and preparative scale separations.

220 hromatographic conditions, and even worse in preparative scale settings.

221 uct inhibition of the evolved enzyme enabled preparative scale synthesis of a single product diastere

222 ied with respect to substrate scope and also preparative scale synthesis.

223 ty (>99.9% de and ee), high yields, and on a preparative scale via benzofuran cyclopropanation with e

224 The reaction has been demonstrated on the preparative scale with 72% isolated yield and 99% Markov

225 Reductions can be accomplished on a preparative scale with as little as 0.05 mol % Ru cataly

226 aphic techniques, both at the analytical and preparative scale, are used also in the identification o

227 h catalyst and microbe, and can be used on a preparative scale, represents a new strategy for chemica

228 catalyzed dimerization can be conducted in a preparative scale, this simple synthesis of trans-1,2-di

229 unusual thermodynamic cycle is employed on a preparative scale, where mechanical energy is used to bu

230 ds for the synthesis of such polymers on the preparative scale.

231 synthesis of the phlorin were performed on a preparative scale.

232 930 TTN and 96% ee), and can be performed on preparative scale.

233 94 % ee; >98 % de) and can be performed on a preparative scale.

234 high levels of enantioselectivity, even on a preparative scale.

235 e at promoting the cyclization reaction on a preparative scale.

236 [2',2',3'-(2)H(3)]-solifenacin fumarate on a preparative scale.

237 olubility of 4 prevented its resolution on a preparative scale.

238 synthetic tool for accessing materials on a preparative scale.

239 n the bioanalytical space, especially at the preparative scale.

240 eric excess), and can be performed easily on preparative scale.

241 and C-S bonds in chemoenzymatic cascades on preparative scale.

242 he utility of the system was demonstrated by preparative-scale applications.

243 Preparative-scale aziridinations can be easily achieved

244 The preparative-scale catalytic aminooxygenation reaction (g

245 Strategies for optimized preparative-scale electrolyses may then be devised on th

246 Preparative-scale electrolyses showed that carbon monoxi

247 f methanol or formate could be detected upon preparative-scale electrolysis of CO2 on the same electr

248 extraction, flash column chromatography, and preparative-scale high performance liquid chromatography

249 dition (InCl(3), 0.32 mM) was performed on a preparative-scale providing the 5-isocorrole in an isola

250 A preparative-scale reaction to deliver >90 mmol of produc

251 In a preparative-scale reaction, unreacted (S)-(+)-butanoate

252 s often a limitation in adopting enzymes for preparative-scale synthesis, reaction with demanding sub

253 A novel preparative-scale triple gas chromatographic system, equ

254 providing a powerful tool when deployable on preparative-scale.

255 s to the desired hydroxylated derivatives at preparative scales (0.4 g) and in high isolated yields (

256 asymmetric methods have seen limited use on preparative scales (more than a gram).

257 ubstituted derivatives can be synthesized on preparative scales, using a chemoenzymatic approach.

258 mbered ring systems stereoselectively and on preparative scales.

259 r concentration of the polyphenols from PSP, preparative separation into two fractions, designated an

260 Preparative separation of membrane protein loaded nanodi

261 superior performance for both analytical and preparative separation of various physiologically releva

262 Counter-current chromatography (CCC) is a preparative separation technique working with the two li

263 ility" and therefore has great potential for preparative separations.

264 ficant production rate improvements in (semi)preparative SFC.

265 from a water extract of Se-rich yeast using preparative size exclusion, anion exchange, and capillar

266 The mAb HMW fractions were collected using preparative size-exclusion chromatography (SEC) and exte

267 or types and their successful application in preparative solar syntheses.

268 All sample preparative steps including magnetic stirring assisted D

269 (MALDI-ToF), REIMS based methods require no preparative steps nor time-consuming cell extractions.

270 g data, are nonetheless dependent on various preparative steps to generate DNA fragments of required

271 hondrial activity and efficiency, and, after preparative steps, it takes 6-8 h to complete.

272 linical laboratories without any preanalysis preparative steps.

273 n be obtained from commercial sources in two preparative steps.

274 ite materials, critically examine the viable preparative strategies geared to craft intimate CP-NC na

275 cal synthesis of AMPDs, through nanoparticle preparative strategies, to the most recent applications

276 Finally, we demonstrate a preparative strategy for obtaining pure bioorthogonally

277 entary methods: a MALDI-MS method and a semi-preparative sub-fractionation.

278 ic trans-dinaphthyl isomers were resolved by preparative supercritical fluid chromatography (SFC) on

279 Also, at low ethylene pressures, preparative syntheses of several 2,3-disubstituted 1,3-b

280 anding ketones and amines, which include the preparative synthesis of N-substituted beta-amino ester

281 ed solution that is more characteristic of a preparative synthetic reaction.

282 ent evolution of a multidimensional GC-GC-GC preparative system, now combined with an online LC prese

283 With preparative tandem affinity purification followed by MS

284 ayer-compression mechanism revealed a simple preparative technique to produce nanosheets in 95% overa

285 F-enzyme composites with special emphasis on preparative techniques and the synergistic effects of en

286 Preparative therapy for the transplant consisted of high

287 The application of preparative thin layer chromatography-2,2-diphenyl-1-pic

288 so partially epimerized to arborisidine upon preparative TLC purification (eluent: MeOH/CHCl(3) satur

289 n mass spectrometry based proteomics or as a preparative tool for analyte purification, fractionation

290 At week 12, LDL-C reduction measured by preparative ultracentrifugation (least squares mean [sta

291 xylate carbene series that enjoys widespread preparative use, or to the class of mononuclear half-san

292 To demonstrate the preparative utility of this method in the context of bio

293 onalization, few intermolecular processes of preparative value exist.

294 pot operations that significantly extend the preparative value of diene-transmissive Diels-Alder sequ

295 Separations can be broadly categorized as preparative, where the objective is to extract purified

296 ing materials has facilitated the underlying preparative work.

297 xy-6,6-dimethylbicyclo[3.1.1]heptan-2-one in preparative yield (65% on a multigram scale).

298 xides, giving quantitative conversions, high preparative yields and excellent chemoselectivity.

299 able catalyst-controlled site-selectivity in preparative yields over a range of topologically diverse

300 didichlorophosphorylated diamondoids in high preparative yields.