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1 n clock that intrinsically oscillates within presomitic mesoderm.
2 ding the primitive streak, the node, and the presomitic mesoderm.
3 be readouts of a "segmentation clock" in the presomitic mesoderm.
4 rated by internal cells or compaction of the presomitic mesoderm.
5 regionalisation when located in the anterior presomitic mesoderm.
6  recently formed somites and in the anterior presomitic mesoderm.
7 marker genes X-Delta-2 and X-ESR5 within the presomitic mesoderm.
8 sic helix-loop-helix (bHLH) gene, within the presomitic mesoderm.
9 slow muscle differentiation from uncommitted presomitic mesoderm.
10 rtebrae, are rhythmically generated from the presomitic mesoderm.
11 ains the pool of caudal progenitor cells and presomitic mesoderm.
12 ion of the transcriptome taking place in the presomitic mesoderm.
13 d activates Notch signalling in the anterior presomitic mesoderm.
14 expression of a number of clock genes in the presomitic mesoderm.
15 he period of cyclic gene oscillations in the presomitic mesoderm.
16 llate in mouse do not cycle across the chick presomitic mesoderm.
17 rarp expression was completely absent in the presomitic mesoderm.
18  stem cells into lateral plate, cardiac, and presomitic mesoderm.
19 nals now elicit RA synthesis in neighbouring presomitic mesoderm.
20 f Drosophila and somitogenesis in vertebrate presomitic mesoderm.
21  somites, are rhythmically produced from the presomitic mesoderm.
22 derm and the posterior neural plate, not the presomitic mesoderm.
23 myotome of developing somites but not in the presomitic mesoderm.
24 rget gene expression throughout the node and presomitic mesoderm.
25 al for establishing segmental pattern in the presomitic mesoderm.
26 o, and loss of cyclic gene expression in the presomitic mesoderm.
27 olecular segmentation clock operating in the presomitic mesoderm.
28 ion coordination among adjacent cells in the presomitic mesoderm.
29  sequentially in a rhythmic fashion from the presomitic mesoderm.
30 -1 is no longer expressed in the somites and presomitic mesoderm.
31 omites (0 and -1) at the anterior end of the presomitic mesoderm.
32 ressed in a segmental pattern in the rostral presomitic mesoderm.
33 the oscillations of neighboring cells in the presomitic mesoderm.
34 ssion of genes such as lunatic fringe in the presomitic mesoderm.
35 es cause them to detach from the unsegmented presomitic mesoderm [1-3].
36  we show that beta1-integrin in the anterior presomitic mesoderm activates canonical Wnt signalling i
37 o, transcripts for Mf3 are restricted to the presomitic mesoderm and anterior neurectoderm and mesode
38 onic axis by regulating cell motility in the presomitic mesoderm and by controlling specification of
39 2 to restrict the anterior boundaries of the presomitic mesoderm and caudal progenitor pool.
40 pressed in a dynamic pattern in paraxial and presomitic mesoderm and developing somites during mouse
41  her1 and Delta D expression in the anterior presomitic mesoderm and disrupts myogenic differentiatio
42 inal cord, which is maintained by underlying presomitic mesoderm and FGF signalling, and neuronal dif
43 ph and ephrin signaling in the patterning of presomitic mesoderm and formation of the somites.
44 fic manner in the presumptive somites of the presomitic mesoderm and is required for normal somitogen
45 transcription factors TBX6 and PAX3 underpin presomitic mesoderm and neural crest, respectively.
46 cs the inducing effects of notochord on both presomitic mesoderm and neural plate explants of amniote
47                          Co-cultures between presomitic mesoderm and neural tube also supported vascu
48 e dsx, terra is transiently expressed in the presomitic mesoderm and newly formed somites.
49  of the DSL gene family, is expressed in the presomitic mesoderm and posterior halves of somites.
50 of gene expression by microarray between the presomitic mesoderm and the 5 most recently formed somit
51 erior Hox genes and that of marker genes for presomitic mesoderm and the chordoneural hinge.
52 ral tube, and by myogenic progenitors in the presomitic mesoderm and the hypaxial somites.
53  Pax3 emerging as the gatekeeper between the presomitic mesoderm and the myogenic lineage.
54 are expressed at the transition zone between presomitic mesoderm and the segmented somites.
55  the presumptive somite from the rest of the presomitic mesoderm and the subsequent morphological cha
56 ri somites formed without convergence of the presomitic mesoderm and were composed of only two cells
57 d in a dynamic, segmental pattern within the presomitic mesoderm, and alterations in the function of
58 ') intrinsic to the cells in the unsegmented presomitic mesoderm, and is manifested in cyclic transcr
59 bx6 is expressed in the primitive streak and presomitic mesoderm, and is sharply down-regulated upon
60 of Gdf11 expression in the primitive streak, presomitic mesoderm, and tail bud.
61 n somite number and size, restriction of the presomitic mesoderm anterior border, somite chevron morp
62 tablishment of a segmental prepattern in the presomitic mesoderm, anteroposterior patterning of each
63 erative manner in the developing somites and presomitic mesoderm, as is the Eph receptor EphA4.
64 ricted to the rostral-most somitomere of the presomitic mesoderm, at the times corresponding to the e
65  border, decreased adhesion at the notochord-presomitic mesoderm border, and tension at boundaries wi
66 s demonstrated that Cerr1-expressing somitic-presomitic mesoderm, but not older Cerr1-nonexpressing s
67 d production of spinal cord neurectoderm and presomitic mesoderm cells from neuromesodermal progenito
68              We provide direct evidence that presomitic mesoderm cells oscillate asynchronously in ze
69  is to keep the oscillations of neighbouring presomitic mesoderm cells synchronized.
70 nscriptional oscillations of cyclic genes in presomitic mesoderm cells.
71            Dynamic expression of FGF8 in the presomitic mesoderm constitutes the wavefront of determi
72                     By employing explants of presomitic mesoderm cultured with constant levels of Wnt
73 the mesodermal compartment, genes regulating presomitic mesoderm differentiation are downregulated in
74 ly or indirectly regulates genes involved in presomitic mesoderm differentiation, somite formation an
75 ecific dependency on Hippo signalling during presomitic mesoderm differentiation-and provide an initi
76 itive endoderm and higher Wnt signals induce presomitic mesoderm differentiation.
77 ic mesoderm exhibits RALDH-2-IR but thoracic presomitic mesoderm does not.
78  Adaxial cells become distinguishable in the presomitic mesoderm during late gastrulation by their ex
79 eriodic cleavage of somites from unsegmented presomitic mesoderm during vertebrate segmentation.
80                                     Cervical presomitic mesoderm exhibits RALDH-2-IR but thoracic pre
81 ollagen explant model was developed in which presomitic mesoderm explants formed a vascular plexus in
82 yoD activation by recombinant Shh protein in presomitic mesoderm explants is defective in Myf5 null e
83 and induce dermomyotome marker expression in presomitic mesoderm explants, supporting the hypothesis
84 enous Myf5 expression in 10T1/2 cells and in presomitic mesoderm explants.
85 ovirus to overexpress Gli1, Gli2 and Gli3 in presomitic mesoderm explants.
86 -8 is normally downregulated within lateral (presomitic) mesoderm following gastrulation.
87 mites of Shh null embryos and in explants of presomitic mesoderm from wild-type and Myf5 null embryos
88              Mouse-avian chimeras with mouse presomitic mesoderm grafts had graft-derived endothelial
89 ght to an end through a process in which the presomitic mesoderm, having first increased in size, gra
90 trikingly, X-Delta-2 is expressed within the presomitic mesoderm in a set of stripes that corresponds
91 ownstream targets of Notch activation in the presomitic mesoderm, including EphA4, were transcribed n
92 ensive zone of unsegmented mesenchyme (i.e., presomitic mesoderm) intervening between the tail bud an
93 nction in stimulating the differentiation of presomitic mesoderm into dermomyotome.
94 role in the translation of the patterning of presomitic mesoderm into somites.
95                            It is likely that presomitic mesoderm is a vertebrate innovation made poss
96 eling, we demonstrate that C&E of the medial presomitic mesoderm is achieved by cooperation of planar
97                Notch pathway activity in the presomitic mesoderm is fundamental for management of syn
98 derm and neural plate, but its expression in presomitic mesoderm is initially unchanged.
99 nos, expression of genes in undifferentiated presomitic mesoderm is initiated, but not maintained.
100                       Expression of terra in presomitic mesoderm is restricted to cells that lack exp
101 ing model of somitogenesis supposes that the presomitic mesoderm is segmented into somites by a clock
102 ence of notochord (noto mutants) or when the presomitic mesoderm is substantially reduced (tbx16 muta
103 Expression of Thylacine is restricted to the presomitic mesoderm, localising to the anterior half of
104 and HRT3 exhibited dynamic expression in the presomitic mesoderm, mirroring the expression of other c
105  in a complex pattern that includes paraxial presomitic mesoderm, notochord, branchial arches and neu
106 a segmental prepattern is established in the presomitic mesoderm of all these mutants and hox gene ex
107            When ectopically expressed in the presomitic mesoderm of chick embryos in ovo, Wnt-1 diffe
108 ature Hes7 transcripts are stabilized in the presomitic mesoderm of mutant mice, suggesting that both
109 tures dramatic loss of expression within the presomitic mesoderm of Notch/Delta pathway components an
110 in the Notch pathway were not altered in the presomitic mesoderm of paraxis(-/-) embryos.
111 h required for transcription in the anterior presomitic mesoderm of paraxis, Mesp1, Mesp2, Hes5, and
112 of Dll1 transcripts is also increased in the presomitic mesoderm of PS1(-/-) embryos, while the level
113 ate Notch ligand, is markedly reduced in the presomitic mesoderm of PS1-/- embryos compared to contro
114  a similar cycling expression pattern in the presomitic mesoderm of somite stage mouse embryos.
115         Marker analysis revealed that in the presomitic mesoderm of the mutant embryos, sharply demar
116 ly traveling segmentation clock waves in the presomitic mesoderm of the organoids, recapitulating cri
117                                          The presomitic mesoderm of vertebrates undergoes a process o
118 es not alter the expression of AmphiHox-1 in presomitic mesoderm or of alkali myosin light chain (Amp
119  The asymmetrical expression of Nr2f2 in the presomitic mesoderm overlaps with the asymmetry of the r
120                            Paraxial tissues (presomitic mesoderm plus neural plate and notochord) wer
121 is is established at the anterior end of the presomitic mesoderm prior to overt somitogenesis in resp
122 s of gene expression that travel through the presomitic mesoderm (PSM) and arrest at the position of
123 nic axis by sequential segmentation from the presomitic mesoderm (PSM) and differentiate into the seg
124 led somites are periodically formed from the presomitic mesoderm (PSM) and give rise to the vertebral
125 n clock are synchronized across cells in the presomitic mesoderm (PSM) and result in tissue-level wav
126            During this process, cells in the presomitic mesoderm (PSM) are first patterned into segme
127 ming of SHH and BMP signals controls whether presomitic mesoderm (PSM) cells will adopt either a chon
128 (NM) stem cells generate neural and paraxial presomitic mesoderm (PSM) cells, which are the respectiv
129 ock, a molecular oscillator expressed within presomitic mesoderm (PSM) cells.
130                            We show here that presomitic mesoderm (psm) cultured in the presence of Sh
131      Lunatic fringe (Lfng) expression in the presomitic mesoderm (PSM) cycles in the posterior PSM, i
132 e continuously produced posteriorly from the presomitic mesoderm (PSM) during body formation.
133 st, a cell motility gradient drives paraxial presomitic mesoderm (PSM) expansion, resulting in compre
134 by an ENU-induced mutation that disrupts the presomitic mesoderm (PSM) expression of Notch pathway ge
135 togenesis, cells are recruited to the caudal presomitic mesoderm (PSM) from the primitive streak (and
136 hicken embryo to demonstrate that the caudal presomitic mesoderm (PSM) has a key role in axis elongat
137 use embryo, timely somite formation from the presomitic mesoderm (PSM) is controlled by the "segmenta
138 ion of the Mesp genes within segments of the presomitic mesoderm (PSM) of different vertebrate specie
139 ic flux impacts embryonic development, using presomitic mesoderm (PSM) patterning as the experimental
140 omitogenesis model by confining hPSC-derived presomitic mesoderm (PSM) tissues in microfabricated tre
141  lunatic fringe (lfng) expression within the presomitic mesoderm (PSM), a hes6a gradient in the PSM n
142  motile cells that eventually constitute the presomitic mesoderm (PSM), a tissue that plays an import
143 e/notochord and surface ectoderm in cultured presomitic mesoderm (PSM), and is accompanied by a marke
144 Xena) localizes to the cell periphery in the presomitic mesoderm (PSM), and is enriched at intersomit
145            This operates in each cell of the presomitic mesoderm (PSM), but the individual cells drif
146 d signaling oscillations in cells within the presomitic mesoderm (PSM), from which somites, the preve
147 ng this process, paired somites bud from the presomitic mesoderm (PSM), in a process regulated by a g
148 oth genes are transcribed in the unsegmented presomitic mesoderm (PSM), newly formed somites, adaxial
149 anics of this elongation, which requires the presomitic mesoderm (PSM), remain poorly understood.
150 f Snail 1 and Snail 2 in the mouse and chick presomitic mesoderm (PSM), respectively.
151 terior-to-anterior signaling gradient in the presomitic mesoderm (PSM), which controls cell maturatio
152  of somites are rhythmically produced by the presomitic mesoderm (PSM).
153 ythmic activity of signaling pathways in the presomitic mesoderm (PSM).
154 n of epithelial somites from the mesenchymal presomitic mesoderm (PSM).
155 es arise from somites, which derive from the presomitic mesoderm (PSM).
156 rm by an iterative process from unsegmented, presomitic mesoderm (PSM).
157  the somites, are rhythmically produced from presomitic mesoderm (PSM).
158 d DeltaD in the zebrafish nervous system and presomitic mesoderm (PSM).
159 ior positioning of boundary formation in the presomitic mesoderm (PSM).
160 ion, known as the segmentation clock, in the presomitic mesoderm (PSM).
161 ols the timing of maturation of cells in the presomitic mesoderm (PSM).
162 velike along the anteroposterior axis of the presomitic mesoderm (PSM).
163 itiation of transcription in the unsegmented presomitic mesoderm (PSM).
164 four distinct modules: dynamic events in the presomitic mesoderm, segmental determination, somite ant
165 oid was composed of a neural tube flanked by presomitic mesoderm sequentially segmented into somites.
166        A molecular segmentation clock in the presomitic mesoderm sets the pace of somite formation(4)
167                           Here, we find that presomitic mesoderm solidification is driven by an intri
168 xamined cell survival and gene expression in presomitic mesoderm, somites and neural tube of developi
169 rtebral patterning, Btg2 is expressed in the presomitic mesoderm, tail bud, and somites during somito
170 nally, we find that forest embryos have more presomitic mesoderm than prairie embryos and that this c
171  to (i) maintain the Fgf8 'wavefront' in the presomitic mesoderm that underpins axial elongation, (ii
172  find that, soon after segmentation from the presomitic mesoderm, the future myotome spreads across t
173 entation clock) operates in the cells of the presomitic mesoderm, the immature tissue from which the
174 lated to continuously release cells into the presomitic mesoderm throughout somitogenesis is not unde
175              Microarray studies of the mouse presomitic mesoderm transcriptome reveal that the oscill
176 fng, Hes1, Hes5 and Hey1 is disrupted in the presomitic mesoderm, we suggest that the somitic aberrat
177        These genes are thought to act in the presomitic mesoderm when cells form prospective somites,
178                   Cadherins are expressed in presomitic mesoderm where they delineate cells.
179 show that Fgf8 and Fgf17 are required in the presomitic mesoderm, whereas Fgf18 is required in the so
180      Cells of the tail bud and the posterior presomitic mesoderm, which control posterior elongation(
181 w normal expression of Wnt inhibitors in the presomitic mesoderm, which in turn constrain the levels
182 s towards definitive endoderm, precardiac or presomitic mesoderm within the first 24 h of differentia
183 s are less severe for gene expression in the presomitic mesoderm, yet severe segmentation phenotypes

 
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