ライフサイエンスコーパス: presynaptic

1 postsynaptic and the effects of mTORC2 were presynaptic.

2 withdrawal indicative of neuroadaptations of presynaptic 5-HT receptors.

3 synaptic transmission through activation of presynaptic A(1) receptors.

4 Thus, any presynaptic action potential may elicit temporally highl

5 Analysis of the presynaptic action potential's (AP(syn)) role in synapti

6 ansmitter release that occurs independent of presynaptic action potentials (APs) shows significant se

7 esicles release their content independent of presynaptic action potentials (APs).

8 Many presynaptic active zone (AZ) proteins have multiple regu

9 Our current knowledge of the presynaptic active zone function relies on structure-fun

10 ation and release.SIGNIFICANCE STATEMENT The presynaptic active zone is composed of scaffolding prote

11 Piccolo, a presynaptic active zone protein, is best known for its r

12 unctional link between this disorder and the presynaptic active zone.

13 How functional assembly of presynaptic active zones is controlled via trans-synapti

14 ther a large number of vesicles at the IHC's presynaptic active zones, allowing high rates of sustain

15 At presynaptic active zones, arrays of large conserved scaf

16 paralleled by an imbalance in GABA/glutamate presynaptic activity and alteration of synaptic plastici

17 phosphotyrosine-phosphatases (LAR-RPTPs) are presynaptic adhesion molecules that interact trans-synap

18 Neurexins are presynaptic adhesion molecules that organize synapses by

19 low directly from the weight profiles of its presynaptic afferents.

20 tools to investigate the contribution of the presynaptic alpha3beta2 nAChR subtype to the train-of-fo

21 One presynaptic amacrine cell was identified as semilunar ty

22 -term depression by mechanistically distinct presynaptic and postsynaptic actions.

23 an plasticity(1), whereby similarity between presynaptic and postsynaptic activity selectively streng

24 Spike fidelity was affected by both presynaptic and postsynaptic changes after ear occlusion

25 esting distinct downstream mechanisms in the presynaptic and postsynaptic compartments.

26 echanisms are and the relative importance of presynaptic and postsynaptic contributions to the faithf

27 dering the actions of antipsychotic drugs on presynaptic and postsynaptic dopamine dysregulation, thi

28 uced excitatory synaptic plasticity involves presynaptic and postsynaptic elements as well as adjacen

29 Both presynaptic and postsynaptic forms of homeostasis are im

30 e propose that CHL1 regulates DRD2-dependent presynaptic and postsynaptic functions.

31 These synapses undergo bidirectional presynaptic and postsynaptic homeostatic changes with in

32 ting as revealed by the increase of anatomic presynaptic and postsynaptic markers in the peri-infarct

33 BAergic transmission is mediated by multiple presynaptic and postsynaptic mechanisms.

34 ergic neurons increasing release of ACh onto presynaptic and postsynaptic nAChRs in primary auditory

35 rons assemble synapses with highly organized presynaptic and postsynaptic nanomachines that are align

36 ssion of complementary molecular programs in presynaptic and postsynaptic neurons.

37 neurin inhibitor-induced tonic activation of presynaptic and postsynaptic NMDARs at the spinal cord l

38 rin inhibitor-induced aberrant activation of presynaptic and postsynaptic NMDARs in the spinal cord.

39 ex intercellular signaling between potential presynaptic and postsynaptic partners, the extracellular

40 lobal scaling therefore operates on both the presynaptic and postsynaptic sides to maintain target ce

41 t catalyze O-GlcNAcylation are found at both presynaptic and postsynaptic sites, and O-GlcNAcylated p

42 though STP parameters estimated from ongoing presynaptic and postsynaptic spiking are highly uncertai

43 ped a model that, using only observations of presynaptic and postsynaptic spiking, aims to describe t

44 d nonsynaptic effects based only on observed presynaptic and postsynaptic spiking.

45 We identified two presynaptic and two postsynaptic steps of synaptic trans

46 apse for the study of neurotransmission, its presynaptic AP waveform has never been directly studied,

47 ered around the shape and propagation of its presynaptic AP waveform.

48 axonal anterograde transport of APP, reduced presynaptic APP levels, and increased synaptic density.

49 APPPS1 mice, which overexpress APP, reduced presynaptic APP levels, restored synapse number and impr

50 oltage-gated calcium channels do not mediate presynaptic assembly.

51 Bassoon was shown to negatively regulate presynaptic autophagy in part by scaffolding Atg5.

52 synaptic GluRs, far less is understood about presynaptic auxiliary GluR subunits and their functions.

53 These synapses are typically configured as presynaptic axon terminations onto postsynaptic dendrite

54 However, electrical stimulation of presynaptic axons, conventionally used to evoke synaptic

55 protein family are evolutionarily conserved presynaptic AZ molecules that regulate presynaptic calci

56 ed both the turnover of dendritic spines and presynaptic boutons as well as the generation of new fil

57 w they are trafficked to and anchored within presynaptic boutons, and the mechanisms that allow them

58 nd are formed by an essential interaction of presynaptic C1ql3 with postsynaptic Bai3.

59 urotransmission in the brain is regulated by presynaptic Ca(2+) concentrations.

60 ng chelators and imaging both indicated that presynaptic Ca(2+) influx decreased after noise exposure

61 These experiments indicate that presynaptic Ca(2+) influx is homeostatically regulated i

62 ustic conditions were a result of changes in presynaptic Ca(2+) influx.

63 equently, depolarization of one IHC triggers presynaptic Ca(2+)-influx at active zones in the entire

64 type currents that correlated with a loss in presynaptic Ca(V) 2 channel numbers.

65 p recordings demonstrated a reduction of all presynaptic Ca(V) 2 channel subtype currents that correl

66 s, cell-specific alternative splicing of the presynaptic Ca(V) channel Cacna1b gene modulates opioid

67 Our results support a model in which presynaptic Ca(v) channels serve both as organizers of s

68 Presynaptic Ca(V)2 channels are essential for Ca(2+)-tri

69 ax Ca(V)2 suggests that the core features of presynaptic Ca(V)2 channels were established early durin

70 of beta- and gamma-synucleins or effects on presynaptic calcium and are consistent with a role for s

71 or function at the calyx synapse in coupling presynaptic calcium channels to release sites.

72 erved presynaptic AZ molecules that regulate presynaptic calcium channels, synaptic transmission and

73 tion depends on their tight association with presynaptic calcium channels.

74 The overall properties of presynaptic calcium ion channels appeared normal, as ref

75 high-frequency signal transmission from the presynaptic calyces to the postsynaptic medial nucleus o

76 Presynaptic calyx recordings revealed that 3,5-DHPG shif

77 pses depends on a Ca(2+)-induced increase in presynaptic cAMP that is mediated by Ca(2+)-sensitive ad

78 mice (stb cKO) display impaired transport of presynaptic cargos, reduced synapse density and active z

79 a motor adapter linking kinesin-1 motor and presynaptic cargos.

80 n was critical for structural and functional presynaptic CB(1)-iLTD.

81 after ear occlusion and was only affected by presynaptic changes after noise-rearing.

82 ics in Caenorhabditis elegans, we solved the presynaptic circuit for depolarization of the sleep-acti

83 synapses vary significantly depending on the presynaptic compartments so that these output neurons ca

84 enzymes functionally interact with the Rad51 presynaptic complex (PSC).

85 hyrin, and neuroligin 2 and does not involve presynaptic component vesicular GABA transporters.

86 ll as their localization with respect to the presynaptic components involved in transmitter release,

87 ntent change, we dialyzed glutamate into the presynaptic cytosol or blocked the vesicular glutamate u

88 ic vesicles were fused, the rapid buildup of presynaptic cytosolic Na(+) promoted vesicle recycling a

89 n (e.g., by blocking inhibitory feedback via presynaptic D2 auto-receptors).

90 30% of retinotectal synaptic targets are the presynaptic dendrites of GABAergic interneurons, and GAD

91 GAD67-GFP interneurons are a source of these presynaptic dendrites.

92 Hence, an adaptive form of presynaptic depression stabilizes neurotransmission duri

93 ke fidelity primarily depended on changes in presynaptic depression, with some contribution from chan

94 synchronized with BC axonal differentiation, presynaptic differentiation of the AII ACs is not depend

95 he A1 insert increases neurexin recruitment, presynaptic differentiation, and synaptic transmission m

96 an occur via homosynaptic mechanisms-such as presynaptic dopamine autoreceptors and dopamine transpor

97 s novel therapeutic approaches for targeting presynaptic dopamine dysfunction in patients with schizo

98 Flies with attenuated IP(3)Rs in these presynaptic dopaminergic neurons exhibit shortened fligh

99 gand that allows assessment of nigrostriatal presynaptic dopaminergic terminal integrity.

100 Presynaptic downscaling was associated with an activity-

101 This "presynaptic downscaling" maintained the relative differe

102 r, how loss of SV2A function translates into presynaptic dysfunction and ultimately seizure activity

103 nate strategy for achieving local control of presynaptic effectors that, opposite to using receptor i

104 ar recording configuration revealed that the presynaptic effects of (2R,6R)-HNK were synapse-selectiv

105 These results indicate that the presynaptic effects of alpha-synuclein depend on specifi

106 hese puncta were juxtaposed to immunolabeled presynaptic efferent terminals.

107 Phosphatidylserine (PS) on presynaptic elements binds GPR56 in a domain-specific ma

108 nule number, length, and contact with distal presynaptic elements.

109 d by an evolutionarily conserved activity of presynaptic ENaC channels in both Drosophila and mouse.

110 splacement between excitatory and inhibitory presynaptic ensembles.

111 ching motion arises in the interplay between presynaptic excitatory and inhibitory circuit elements.

112 Presynaptic excitatory neurons spanned layers 2/3 and 4

113 We show presynaptic expression of TRPV1 by immunoelectron micros

114 levated spine turnover and the generation of presynaptic filopodia are microglia-dependent processes.

115 initial response window that still contains presynaptic firing rate information before the synapse i

116 s rate-invariant, GluA3 extends the range of presynaptic firing rates over which rate information in

117 pression, and makes it less dependent on the presynaptic firing rates.

118 to the temporal difference between post- and presynaptic firing.

119 se proteins regulate synapse development and presynaptic function in a developing neuronal circuit in

120 ynaptic roles for mTOR, whether it regulates presynaptic function is largely unknown.

121 ic vesicle pools, and a novel, nonapoptotic, presynaptic function of the BAD-BAX-caspase-3 cascade.SI

122 leration of local ATP synthesis, and impairs presynaptic function under oxidative conditions.

123 in glutamatergic synapse development and in presynaptic function, we used CAST knockout (KO) and ELK

124 uring adolescence preferentially reduces the presynaptic functionality of GABAergic activity over tha

125 age-gated Ca(2+) channels that support their presynaptic functions.

126 Our previous work demonstrated that the presynaptic G protein-coupled receptor metabotropic glut

127 gated the modulation of this microcircuit by presynaptic GABA(B) receptors (GABA(B)Rs) in the rodent

128 At the Drosophila neuromuscular junction, a presynaptic GluR, DKaiR1D, localizes near active zones a

129 s required for the homeostatic regulation of presynaptic GluRs.

130 is pathway suppresses facilitated release of presynaptic glutamate during synaptic activity by regula

131 Presynaptic glutamate receptors (GluRs) modulate neurotr

132 ry synaptic density and selectively enhances presynaptic glutamate release, which is impaired on alph

133 terol is a negative modulator of spontaneous presynaptic glutamate release.

134 at soluble amyloid-beta (Abeta)(42), elicits presynaptic glutamate release.

135 s membrane potential rather than acting as a presynaptic glutamate transporter.

136 CAST/ELKS are positive regulators of presynaptic growth and are suppressors of active zone ex

137 AST/ELKS proteins are positive regulators of presynaptic growth and are suppressors of AZ expansion a

138 egulates excitatory gain onto D1(+)-MSNs via presynaptic H(3) receptor-dependent long-term depression

139 ting as an antagonist/inverse agonist of the presynaptic histamine 3 receptor.

140 We showed that depolarizing changes in the presynaptic holding potential can increase the rate at w

141 Here, we demonstrate that presynaptic homeostatic plasticity (PHP) is induced at d

142 ify an evolutionarily conserved mechanism of presynaptic homeostatic plasticity induced by ALS-like m

143 is is also evidence that glia participate in presynaptic homeostatic plasticity, invoking previously

144 tersection of glial epigenetic signaling and presynaptic homeostatic plasticity.

145 GluR functionality, a process referred to as presynaptic homeostatic potentiation (PHP).

146 During a screen for genes involved in presynaptic homeostatic synaptic plasticity, we identifi

147 e is caused by disruption in the function of presynaptic homomeric GlyRs (rather than postsynaptic he

148 proposed that the receptors responsible are presynaptic homomeric GlyRs, rather than postsynaptic he

149 Presynaptic Igsf8 deletion impairs MF synaptic architect

150 As presynaptic inhibition (PSI) is centrally modulated to a

151 As presynaptic inhibition (PSI) is centrally modulated to a

152 cyclic voltammetry recordings confirmed that presynaptic inhibition of dopamine release by the KOR ag

153 and GABA(C) receptor clustering and disrupts presynaptic inhibition onto RBC terminals.

154 ceptors, GPCRs that mediate highly sensitive presynaptic inhibition, are instead dynamic in axons.

155 s not yet experimentally observed or through presynaptic inhibition.

156 By contrast, presynaptic inhibitory neurons resided within layer 2/3

157 how postsynaptic cells differentiate between presynaptic inputs are unclear.

158 ronment but had lower excitability and fewer presynaptic inputs than those of Ocn-Cre(-) or adult bor

159 ntity of the grafted neurons, and anatomical presynaptic inputs were largely dependent on graft locat

160 lt of reduced microglial engulfment of PS(+) presynaptic inputs.

161 , we revealed that increased excitability of presynaptic interneurons (INs) and decreased intrinsic e

162 ic physiology, we reveal a critical role for presynaptic K(v) channels in synaptic facilitation at pr

163 Presynaptic K(v)1 channel inactivation was mediated by t

164 nd axonal transport of APP thus regulate APP presynaptic levels and synapse homeostasis.

165 The presynaptic ligand cerebellin-1 (Cbln1) and postsynaptic

166 Presynaptic long-term synaptic depression (LTD) plastici

167 ponents of IPSCs were modulated similarly by presynaptic manipulations and manipulations of transmitt

168 Moreover, nicotine depletes presynaptic markers in a manner that is microglia-, D2-

169 ase in striatal dopamine (e.g., because of a presynaptic mechanism).

170 h raises the question of what the underlying presynaptic mechanisms are and the relative importance o

171 eurotransmitter-containing vesicles with the presynaptic membrane.

172 s vesicles were found within 150 nm from the presynaptic membrane; however, no vesicles were at 450-6

173 enula of humans and rodents, is expressed at presynaptic membranes and synaptic vesicles and associat

174 tor neurons or muscle supports a model where presynaptic miR-34 inhibits Nrx-IV to influence active z

175 Thus, presynaptic mitochondria rely on MICU3 to facilitate mit

176 glutamate density in presynaptic terminals, presynaptic mitochondria, and in dendritic spines of xCT

177 , but to do so, they rely on activity-driven presynaptic mitochondrial Ca(2+) uptake to accelerate AT

178 sion extended to neurofilaments and specific presynaptic molecules, providing a mechanism for coregul

179 AST/ELKS are involved in pathways regulating presynaptic morphological properties and Ca(V) 2 channel

180 se size, with each muscle affecting only its presynaptic motor neuron branches.

181 This effect was mediated by presynaptic mu-opioid receptor activation of local parva

182 Together, these results suggest that presynaptic mu-opioid stimulation of local PV(+) interne

183 amate release from mossy fibers by acting on presynaptic muscarinic receptors.

184 We found that this effect requires open presynaptic N-methyl-d-aspartate receptors but not plasm

185 nabinoids, astrocytic calcium signaling, and presynaptic N-methyl-D-aspartate receptors coupled with

186 Elevated presynaptic Na(+) accelerated both slow and rapid forms

187 eover, two-photon Ca(2+) imaging showed that presynaptic Na(+) did not affect the action potential-ev

188 Consequently, presynaptic Na(+) increased the EPSCs and was required t

189 form shape and propagation through this long presynaptic nerve terminal are unknown.

190 ion flux that triggers neurotransmission at presynaptic nerve terminals.

191 synaptogenesis by simultaneously binding to presynaptic neurexin-1alpha and to postsynaptic neurolig

192 c cell adhesion molecules that interact with presynaptic neurexins (NRXNs) and regulate synapse funct

193 CPTX can interact with presynaptic neurexins and postsynaptic AMPA-type ionotro

194 synapses, and generates synapses by bridging presynaptic neurexins and postsynaptic neuroligins.

195 hold changes in the holding potential of the presynaptic neuron.

196 d all three neurexin adhesion molecules from presynaptic neurons of the calyx of Held in the mouse au

197 minority of connections when a large pool of presynaptic neurons was activated [15-19].

198 ts the co-activation of large populations of presynaptic neurons with similar properties and a mixtur

199 c neuron was unrelated to the selectivity of presynaptic neurons, but correlated with the spatial dis

200 tivity and blocked by inhibiting caspases in presynaptic neurons, implicating synaptic dysfunction an

201 or to tune baseline transmission and enhance presynaptic neurotransmitter release in response to dimi

202 s MUNC18-1) is an essential component of the presynaptic neurotransmitter release machinery.

203 A major function of GPCRs is to inhibit presynaptic neurotransmitter release, requiring ligand-a

204 an through a potent homeostatic reduction in presynaptic neurotransmitter release.

205 This cooperative action of presynaptic NMDARs allows to implement synapse-specific,

206 tic NMDARs at the spinal cord level and that presynaptic NMDARs play a prominent role in the developm

207 Phosphorylation of Munc18-1 (Stxbp1), a presynaptic organizer of synaptic vesicle fusion, is a p

208 Consistent with a presynaptic origin of the augmented glutamate release, t

209 d a positive Kv1.2 modulator to mitigate the presynaptic over-inhibition and social impairment of BTB

210 properties shared with DKaiR1D Intriguingly, presynaptic overexpression of dSol-1 is sufficient to en

211 ese cells receive input from defined sets of presynaptic partners and communicate with postsynaptic b

212 is with functional studies of DANs and their presynaptic partners and with comprehensive circuit mode

213 rtners are able to find and connect to their presynaptic partners even when these have been shifted t

214 , this variability reflects a diverse set of presynaptic partners, rather than glomerulus-specific di

215 postsynaptic horizontal cell refinement and presynaptic photoreceptor axon growth.

216 ing all quantitative optical measurements of presynaptic physiology, we reveal a critical role for pr

217 (2+) influx, synaptic vesicles fuse with the presynaptic plasma membrane (PM) to release neurotransmi

218 These forms of presynaptic plasticity appear to be independent of the p

219 of inhibitory transmission (iLTD), a form of presynaptic plasticity that involves a protein-synthesis

220 rences between neuron subtypes, including in presynaptic plasticity, postsynaptic receptor function,

221 LTD and link complex biochemical networks at presynaptic, postsynaptic, and astrocytic sites to the t

222 fixed distributions of dendritic claws while presynaptic processes are plastic.

223 T(-/-) mice revealed decreased expression of presynaptic proteins and abnormal kinase network signali

224 rovide a more detailed view of how these two presynaptic proteins orchestrate their functions to achi

225 g postsynaptic apparatuses and much fewer in presynaptic proteins.

226 retinogeniculate connections, have elevated presynaptic PS exposure and reduced PS engulfment by mic

227 transmission can faithfully transfer ongoing presynaptic rates enabling linear processing, deemed cri

228 mechanism enabling scaled linear encoding of presynaptic rates over behavior-relevant time windows, a

229 ome tasks require ongoing linear transfer of presynaptic rates, seemingly incompatible with nonlinear

230 l cortical neurons via its ability to induce presynaptic recruitment and activation of GAP-43.

231 ium channels with respect to BK channels and presynaptic release components significantly increased f

232 a2delta3 subunits of calcium channels foster presynaptic release of GABA, trigger formation of inhibi

233 exhibit extensive overgrowth in muscle size, presynaptic release sites and postsynaptic glutamate rec

234 ization of neurotransmitter receptors facing presynaptic release sites is a fundamental determinant o

235 active zone proteins may scaffold Ca(V)2s to presynaptic release sites, and synapse structure is Ca(V

236 lly modulate postsynaptic responsiveness and presynaptic release to optimize glutamatergic synaptic t

237 skeleton, such as ARPC2 and WASF1/WAVE1, and presynaptic release.

238 mine (DA) signaling is rapidly terminated by presynaptic reuptake, mediated by the cocaine-sensitive

239 ERT) terminates serotonin signaling by rapid presynaptic reuptake.

240 aling within a peripheral circuit and on the presynaptic side through uniform downscaling of evoked n

241 m scaling can therefore manifest also on the presynaptic side to produce robust and stable circuit ou

242 adened to include uniform downscaling on the presynaptic side.SIGNIFICANCE STATEMENT To date, compens

243 not amplitude, of mEPSC events, confirming a presynaptic site of action that is independent of glutam

244 sted that eurydendroid IPSC size depended on presynaptic spike duration rather than amplitude.

245 ron's receptive field (i.e., its response to presynaptic stimuli) depends on the modulatory state of

246 hat this disorder is associated with blunted presynaptic striatal dopamine.

247 associated with protein synthesis-dependent presynaptic structural changes.

248 e relationship between protein synthesis and presynaptic structural plasticity remains unclear.

249 We found that AII ACs do not elaborate their presynaptic structures, the lobular appendages, until BC

250 xcitatory neurotransmission might serve as a presynaptic substrate for synaptic plasticity coupling d

251 xonal actin dynamics to mobilize and recruit presynaptic SV resources.

252 three Ca(V) 2 subtype channel levels in the presynaptic terminal and not just Ca(V) 2.1.

253 ation of GAP-43 from the axonal shaft to the presynaptic terminal but also its activation in the axon

254 ircuit maturation impacted the calyx of Held presynaptic terminal development and function.

255 dye, we have imaged the AP waveform from the presynaptic terminal of male and female frog NMJs and sh

256 Here, we demonstrate that the presynaptic terminal of the frog NMJ has a very brief AP

257 Efficient neurotransmitter release at the presynaptic terminal requires docking of synaptic vesicl

258 function, structure, and development of the presynaptic terminal which leads to altered short term-d

259 o the normal function and development of the presynaptic terminal, whose properties shape short-term

260 ing the behavior of neurotransmission at the presynaptic terminal.

261 brain, its expression is restricted to a few presynaptic terminals and scattered axonal growth cones.

262 hways regulating morphological properties of presynaptic terminals during an early stage of circuit m

263 ic K(v) channels in synaptic facilitation at presynaptic terminals of the hippocampus upstream of the

264 ry brainstem, synaptic zinc is released from presynaptic terminals to modulate neurotransmission.

265 -type voltage-gated Ca(2+) channels that, at presynaptic terminals, abnormally contributes to evoked

266 en contained PSD fragments, contacted distal presynaptic terminals, and formed secondary synapses.

267 rn neurons had greater spine density, larger presynaptic terminals, and more putative efferent filopo

268 pha-Synuclein is expressed at high levels at presynaptic terminals, but defining its role in the regu

269 ha-synuclein (alphaS), a protein abundant at presynaptic terminals, is associated with a range of hig

270 decreased intracellular glutamate density in presynaptic terminals, presynaptic mitochondria, and in

271 Targeted to presynaptic terminals, preSynTagMA allows discrimination

272 43) plays a central role in the formation of presynaptic terminals, synaptic plasticity, and axonal g

273 ed excitability and Ca(2+) transients in the presynaptic terminals, where Kv1.2 potassium channels ar

274 n and propagation and transmitter release at presynaptic terminals.

275 function of the BAD-BAX-caspase-3 pathway in presynaptic terminals.

276 er ligand-induced activation specifically at presynaptic terminals.

277 in response to the release of glutamate from presynaptic terminals.

278 (alpha-syn), a cytosolic protein enriched in presynaptic terminals.

279 late the initiation of bouton formation from presynaptic terminals.

280 ushroom spines, and had enlarged mossy fiber presynaptic terminals.

281 in excitatory synaptic transmission at both presynaptic termini and postsynaptic termini.

282 DAergic Rit2-KD did not affect presynaptic TH and DAT protein levels in females, nor wa

283 ntington disease transfer anterogradely from presynaptic to postsynaptic neurons in the adult Drosoph

284 rially connected network of neighboring SACs presynaptic to the DSGC.

285 the synaptic vesicle endocytosis and/or the presynaptic trafficking of synaptic vesicles back to the

286 agonist, capsazepine, suggesting it required presynaptic TRPV1.

287 al imaging of endogenous fluorescent labeled presynaptic VAMP2 and postsynaptic PSD95 in long-term cu

288 regulation of genes related to microtubules, presynaptic vesicle alteration, and behavioral alteratio

289 o exhibit an atypical mitochondrion near the presynaptic vesicle clusters at the synapse.

290 oteins and receptors and align with putative presynaptic vesicle release sites.

291 y uPA/uPAR binding, pGAP-43 colocalizes with presynaptic vesicles and triggers their mobilization to

292 in clathrin uncoating during endocytosis of presynaptic vesicles.

293 D2/D3 receptor availability with age, while presynaptic vesicular DA storage (as measured by DTBZ),

294 1C]dihydrotetrabenazine (DTBZ), a measure of presynaptic vesicular DA storage, and [11C]raclopride (R

295 ound that Abeta42 caused the accumulation of presynaptic vesicular glutamate transporter (VGlut) and

296 pH indicators to the microenvironment of the presynaptic voltage gated Ca(2+) channels revealed that

297 For example, presynaptic voltage-gated calcium channels (VGCCs) and p

298 The presynaptic wide-field amacrine cells were reconstructed

299 tood, and the focus of this study was on the presynaptic wide-field amacrine cells, which provided 17

300 pressed, at least in part, via reductions in presynaptic zinc release.