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1 form of homeostatic plasticity is expressed presynaptically.
2 acilitation, suggesting that it is expressed presynaptically.
3 arbor size occur only when SDN is expressed presynaptically.
4 in muscle cells, suggesting that RYRs acted presynaptically.
5 nd found that it also appeared to be located presynaptically.
6 on mediated by endocannabinoids is expressed presynaptically.
7 lfactory sensory neurons (OSNs) is modulated presynaptically.
8 t most of the bandpass filtering is mediated presynaptically.
9 It is also concluded that CRF is not acting presynaptically.
10 utamate receptor activation but is expressed presynaptically.
11 GluR5 immunoreactivity is rarely encountered presynaptically.
12 t it modulates glutamate release probability presynaptically.
13 smission by acting both postsynaptically and presynaptically.
14 ced LTD is Ca2+ independent and is expressed presynaptically.
15 lly on pyramidal and nonpyramidal cells than presynaptically.
16 n, indicating that mu receptors were located presynaptically.
17 effect of ANGII on TS-evoked IPSPs may occur presynaptically.
18 ndicating that opioid receptors were located presynaptically.
19 gether, these results suggest that BDNF acts presynaptically.
20 d regulate the axonal input to these regions presynaptically.
21 hat inhibition of EPSCs by 5-HT was mediated presynaptically.
22 at their excitatory input is also controlled presynaptically.
23 as a component that is induced and expressed presynaptically.
24 d that both forms of depression are mediated presynaptically.
25 y alerting glutamate release or biosynthesis presynaptically.
26 on, suggesting that isoproterenol was acting presynaptically.
27 to modulate striatonigral neurotransmission presynaptically.
28 nalysis suggested that the LTD was expressed presynaptically.
29 receptors and calcineurin, and is expressed presynaptically.
30 belongs to group III and is mainly localized presynaptically.
31 persists at mature TC synapses but is gated presynaptically.
32 ludes synapses that are completely quiescent presynaptically.
33 ision, the highly abundant Ivy cells express presynaptically acting neuromodulators and regulate the
35 e ultrastructurally normal synapses that are presynaptically active but postsynaptically silent and w
36 long-term changes at synapses that were not presynaptically active during the induction, i.e., heter
37 rease in vesicle pool size and turnover rate presynaptically, adaptive changes that extend beyond sim
38 inal cortex, but that cholinergic inputs can presynaptically adjust the impact of this control mechan
41 tic activity, acting as a positive regulator presynaptically and a negative regulator postsynapticall
44 artmentalized pools of PKA, but the roles of presynaptically and postsynaptically anchored forms of P
45 e dopaminergic and serotonergic changes both presynaptically and postsynaptically at four different m
46 rate that KA1 and KA2 subunits are localized presynaptically and postsynaptically at mossy fiber syna
48 knockdown indicate that Bdl is required both presynaptically and postsynaptically for delivering SV c
49 pled receptors nor whether receptors located presynaptically and postsynaptically in a single cell ty
50 lpha2delta-1 subunit basal expression occurs presynaptically and postsynaptically in spinal dorsal ho
51 ound ubiquitously in the CNS and are present presynaptically and postsynaptically regulating synaptic
52 data demonstrate that fasting and leptin act presynaptically and postsynaptically to alter GABAergic
53 at the Y1 and Y2 type NPY receptors act both presynaptically and postsynaptically to depress GABA-med
54 ompelling evidence that Dnlg2 functions both presynaptically and postsynaptically together with Neure
55 atory transmission to trigeminal motoneurons presynaptically and postsynaptically via presynaptic inh
56 odifies GABAergic synaptic transmission both presynaptically and postsynaptically, and this could be
57 en cell adhesion molecules (CAMs), expressed presynaptically and postsynaptically, are thought to gui
58 role in modulating synaptic physiology both presynaptically and postsynaptically, but the regulatory
62 rphology suggesting that HSPGs function both presynaptically and postsynaptically; these defects coul
65 cerebellar LTP is both induced and expressed presynaptically and therefore may be detected by either
66 hese neurons, 5-HT1B receptors are expressed presynaptically, and their activation inhibits GABA rele
67 g induced postsynaptically, DSI is expressed presynaptically as a decrease in GABA release, possibly
69 lu1 receptors for induction but is expressed presynaptically as an increased release probability and
71 ely decreased IPSC amplitudes, acting mostly presynaptically as it increased paired-pulse facilitatio
72 Surprisingly, the latter effect was mediated presynaptically, as HTT overexpression in cortical neuro
74 gic pathways of the trisynaptic circuit both presynaptically at axon terminals and initial segments a
75 confirms that GABA(B)Rs are highly expressed presynaptically at both input and output synapses of SOM
78 ctive form of H-ras (H-ras(G12V)), expressed presynaptically at excitatory synapses in mice, accelera
80 Although CB1Rs are prominently expressed presynaptically at PF synapses, LTD is expressed postsyn
82 ity of both to depress synaptic transmission presynaptically at the concentrations used was confirmed
83 ensory neurons, particularly those expressed presynaptically at the first sensory synapse in the spin
84 t transmission strength is mainly determined presynaptically at the level of individual boutons, poss
86 ) receptor subtypes, only mGlu7 is expressed presynaptically at the Schaffer collateral (SC)-CA1 syna
87 ayer I and can block excitatory transmission presynaptically, at glutamatergic terminals, and postsyn
88 ptic control of network modulation can occur presynaptically, at the axon terminals of the modulatory
89 of differential postsynaptic attenuation or presynaptically because of local regulation of the stren
90 ranule cells, suggesting that CGP 35348 acts presynaptically, blocking receptors that suppress GABA r
91 Thus, orientation selectivity is generated presynaptically both by modulation of bipolar cell outpu
92 tors, which inhibit neurotransmitter release presynaptically, but are thought to be excitatory postsy
94 er long-term potentiation (LTP) is expressed presynaptically, but the exact mechanisms remain unknown
95 n some cases, GABAA receptors are also found presynaptically, but they retain their inhibitory effect
96 pus, long-term potentiation (LTP) is induced presynaptically by activation of cAMP-dependent protein
97 etwork-driven chemical transmission mediated presynaptically by Ca(2+) entry through N-type Ca(2+) ch
100 analogs stimulate the neuromuscular junction presynaptically by inhibiting voltage-gated potassium (K
101 s cell specific, bidirectional and expressed presynaptically by inputs from the lateral amygdala.
102 al transmission at this synapse is modulated presynaptically by several mechanisms, a major one being
103 cific tracing technique labeled thousands of presynaptically connected neurons and revealed that the
104 o siphon sensory neurons, both of which were presynaptically connected to the motor neuron, were impa
105 hermore, the contralateral Abetadelta-fibers presynaptically control ipsilateral C-fiber input to Lam
108 spines and in the numbers of NMDA receptors; presynaptically, converging evidence points to an early
109 GABAergic interactions, mediated in part presynaptically, create an antagonistic and anisotropic
110 ptic Ca(2+) channels, chronic depolarization presynaptically depressed hippocampal neurotransmission.
112 odulated, in part, by CB1 receptors that are presynaptically distributed on noradrenergic axon termin
115 put to spinal cord interneurons is inhibited presynaptically during active wrist movement, and this i
117 ry input to the spinal cord can be modulated presynaptically during voluntary movement by mechanisms
122 uron, Hashimotodani et al. (2017) discover a presynaptically expressed form of long-term potentiation
123 tive zone and has emerged as key mediator of presynaptically expressed forms of synaptic plasticity.
124 ate receptors (mGluRs) represent a family of presynaptically expressed G-protein-coupled receptors (G
125 ity, the predominant form being initiated by presynaptically expressed Gi/o-coupled metabotropic rece
126 e nucleus accumbens core, where it elicits a presynaptically expressed long-term depression of excita
127 apses, Rab3A and RIM1alpha are essential for presynaptically expressed long-term potentiation (LTP),
128 presynaptic release probability and enhanced presynaptically expressed long-term potentiation (LTP).
129 frequency stimulation (HFS) protocol induces presynaptically expressed LTP and LTD at PYR and SLIN in
130 ay to showcase the target-cell dependence of presynaptically expressed NMDA receptor-independent syna
131 wever, the focus has now expanded to include presynaptically expressed plasticity, the predominant fo
132 poor candidate to reverse LTD because it is presynaptically expressed whereas LTD is postsynaptic.
133 atal synapse is postsynaptically induced but presynaptically expressed, the depression being a result
134 Mu and delta OP-LTD, although both being presynaptically expressed, were dissociable in that they
138 , we report that synaptically activated KARs presynaptically facilitate and depress transmission at p
140 in TRPA1-null mice, suggesting that 5,6-EET presynaptically facilitated spinal cord synaptic transmi
142 trum disorder and Down syndrome, is required presynaptically for normal synaptic growth and rapid syn
145 lysis demonstrates that DLIMK1 is necessary, presynaptically, for synapse stabilization, but is not n
147 ses reveals that this variability must arise presynaptically, from variations in the quantity of agon
148 ordings showed that GABA has the capacity to presynaptically gate glutamate release in the DR through
150 A receptors are located postsynaptically and presynaptically, (ii) demonstrating that pyramidal neuro
152 rain-specific miRNA, was exclusively present presynaptically in a sensory-motor synapse where it cons
153 luR6/7 and KA2 immunoreactivity is expressed presynaptically in a subpopulation of glutamatergic term
157 at hippocampal alpha2A-AR-I is localized (1) presynaptically in both noncatecholaminergic and catecho
158 rary to expectations, dysbindin-1 is located presynaptically in glutamatergic neurons and is reduced
160 y a role in the release of neurotransmitters presynaptically in several brain regions and cell types.
161 scular junctions (NMJs), DCAF12 is expressed presynaptically in synaptic boutons, axons, and nuclei o
163 itatory synapses between excitatory neurons, presynaptically in the granule cells and postsynapticall
164 trastructural evidence that KORs are located presynaptically in the guinea pig hippocampal formation.
165 kappa opioid receptors (KORs) may be located presynaptically in the guinea pig hippocampal formation.
166 ms, we find that a distinct pathway operates presynaptically in the motoneuron and can account for ma
168 tsynaptic AMPARs increased the occurrence of presynaptically inactive synapses without changing the r
169 st, long-term exposure to PGE2 (2 mum; 48 h) presynaptically increases excitatory synaptic transmissi
170 sed from JG interneurons could be capable of presynaptically influencing neurotransmission from the o
171 esults indicate that kappa-ORs are poised to presynaptically inhibit diverse afferent signaling to th
172 previously described for AgRP neurons, they presynaptically inhibit the terminals of tonically activ
173 subtypes of glucosensing neurons were either presynaptically inhibited (PIR; 11%) or excited (PER; 8%
174 muscarinic receptors, long-range IPSPs were presynaptically inhibited by M2 receptor activation.
175 pharmacological activation of MORs no longer presynaptically inhibited GABA release, whereas blocking
176 ssion, we found that kappa-receptor agonists presynaptically inhibited glutamate synaptic currents in
178 inwardly rectifying K+ channel currents, and presynaptically inhibiting release of excitatory glutama
179 in VTA brain slices from drinking rats DPDPE presynaptically inhibits GABA(A) receptor mediated IPSCs
184 anglion (STG), a gastric mill network neuron presynaptically inhibits transmitter release from a modu
185 This inhibition is mediated predominantly presynaptically, is active tonically and can be enhanced
186 PAD is also mediated by glutamate acting on presynaptically localized AMPA and kainate receptors.
187 etabotropic glutamate receptors (mGluRs) are presynaptically localized on STN terminals and that acti
189 ontal dopaminergic function by antagonism of presynaptically located dopamine D(2) receptors in this
190 pses, which is likely mediated by activating presynaptically located dopamine D1 class receptors and
191 e, 1 microM galantamine, acting as an APL on presynaptically located nicotinic receptors (nAChRs) tha
193 e we show that GAT-1, which is predominantly presynaptically located, is the major GABA transporter u
195 inistration of amphetamine, a drug that acts presynaptically, markedly reduced the locomotor activity
196 ated in the endocytosis of synaptic vesicles presynaptically, may also function in the endocytosis of
197 se effects were qualitatively similar to the presynaptically mediated decreases in synaptic potential
198 neither paired-pulse depression of IPSPs nor presynaptically mediated facilitation can account for th
200 e that the GABA(B) receptor is positioned to presynaptically modulate afferent transmission by myelin
201 ore, kappaORs are strategically localized to presynaptically modulate DYN afferent input to catechola
202 annabinoid (CB1) receptors are positioned to presynaptically modulate norepinephrine release in the f
203 es within the rostral pole of the LC, 2) may presynaptically modulate other afferents, and 3) are oft
204 glucose-sensing themselves, but rather were presynaptically modulated by changes in extracellular gl
205 ons receiving input from terminals which are presynaptically modulated by DA via D2 receptors, and (3
206 er picrotoxin, indicating that alpha7-nAChRs presynaptically modulated glutamate and not GABA release
211 sted that delta opioid receptors are located presynaptically on axon terminals within the hamster SCN
212 e ganglion cell; thus, the modulation occurs presynaptically on bipolar cell terminals, most likely v
213 tors in the cervical (C6) dorsal horn reside presynaptically on central terminals of primary afferent
214 otropic glutamate receptors that are located presynaptically on certain vagal pancreas-projecting neu
216 The dopamine transporter (DAT), located presynaptically on dopamine neurons, provides a marker f
217 The dopamine transporter (DAT), located presynaptically on dopamine neurons, provides a marker f
221 t GABAB receptor-mediated inhibition may act presynaptically on olfactory nerve axons to modulate the
223 hypothesis that 5HT1B receptors are located presynaptically on retinal axon terminals in the SCN and
224 pretation that 5HT1B receptors are localized presynaptically on retinal terminals in the SCN and that
225 mation processing in the retina 1) by acting presynaptically on rod bipolar cell axon terminals and b
226 be modulated by mu opioid receptors located presynaptically on striatopallidal enkephalinergic neuro
227 ence for the diversity of molecular subtypes presynaptically on the commissural/associational pathway
230 ugh many forms of neurodegeneration initiate presynaptically, only few pathogenic mechanisms are know
231 he extent to which central melanocortins act presynaptically or postsynaptically on MC4-Rs is also un
234 postsynaptic orexin receptors and expressed presynaptically, presumably through a retrograde messeng
236 abotropic glutamate receptors (mGluRs) is to presynaptically reduce synaptic transmission at glutamat
237 inistration to test the hypothesis that MORs presynaptically regulate GABA transmission in the VP and
240 DRD2 short splice variant (expressed mainly presynaptically) relative to DRD2 long (postsynaptic), a
241 e receptors (NMDARs) phasically activated by presynaptically released glutamate are critical for syna
242 mammalian brain and transduce the binding of presynaptically released glutamate to the opening of a t
245 ion depends on the matching and alignment of presynaptically released transmitters and postsynaptic n
246 Our data suggest that opioids may be the presynaptically released, frequency-dependent, associati
249 of the ADAMTS-like protein MADD-4/Punctin, a presynaptically secreted synapse-organizing molecule tha
251 clase activity maintains the balance between presynaptically silent and active synapses, but AC8 play
254 a fraction of nerve terminals are kept in a presynaptically silent state with no measurable Ca(2+) i
255 hR-mediated enhancement of GABA release also presynaptically suppressed the first synapse of the olfa
257 bility that the expression might involve PKA presynaptically, the adenylyl cyclase activator forskoli
259 c modulator is nitric oxide (NO), which acts presynaptically to boost vesicle release and glutamaterg
261 ata indicate that serotonin and GABA can act presynaptically to decrease calcium influx at the retino
264 sults demonstrate that NOS-1-derived NO acts presynaptically to facilitate vagally induced bradycardi
265 This study suggests that calpain may act presynaptically to impair NMJ function in SCS but furthe
267 ses, we show that group I mGluR agonists act presynaptically to increase neurotransmitter release wit
268 tion by endothelial cells, whereas PAMP acts presynaptically to inhibit adrenergic nerves that innerv
269 suggest that group II mGluR stimulation acts presynaptically to inhibit glutamate release by a PKC-de
270 Because cannabinoid receptor agonists act presynaptically to inhibit glutamate release, we examine
272 filtered by GABAergic interneurons that act presynaptically to inhibit sensory transmitter release a
274 se results indicate that cannabimimetics act presynaptically to inhibit the release of neurotransmitt
277 how the timing of action potentials is tuned presynaptically to match these processing demands is not
279 minals, and that enkephalins most likely act presynaptically to modulate the release of other neurotr
280 A cadre of ubiquitin ligases is required presynaptically to orchestrate development and transmiss
285 oup III metabotropic glutamate receptors act presynaptically to reduce the release of glutamate onto
286 e that Drosophila melanogaster miR-1000 acts presynaptically to regulate glutamate release at the syn
287 rs such as serotonin (5-HT) and GABA can act presynaptically to regulate neurotransmitter release at
288 ng them to release a transmitter, which acts presynaptically to regulate neurotransmitter release.
289 euron, it appears that neuronal ghrelin acts presynaptically to stimulate release of the orexigenic p
291 forskolin facilitates synaptic transmission presynaptically via cAMP-dependent protein kinase (PKA).
292 optic nucleus oxytocin neurones directly and presynaptically via inhibition of afferent noradrenergic
293 on inhibitory synaptic strength are mediated presynaptically where 5-HT decreases and NA increases th
296 ology, including deficits in docked vesicles presynaptically, wider synaptic clefts, and simpler seco