ライフサイエンスコーパス: preterm labor

1 fetal membranes during PGN+poly(I:C)-induced preterm labor.

2 ction of amniotic fluid, chorioamnionitis or preterm labor.

3 ntributes to susceptibility for experiencing preterm labor.

4 ck pain, uterine cramps, fetal distress, and preterm labor.

5 plicated or involved in infection-associated preterm labor.

6 ant mother to bacterial products and promote preterm labor.

7 B1 and ZEB2 in two different mouse models of preterm labor.

8 ve strongly linked bacterial infections with preterm labor.

9 ed the development of improved therapies for preterm labor.

10 of which are clinical signs associated with preterm labor.

11 o adverse effects of betaAR agonists used in preterm labor.

12 een implicated in the onset of both term and preterm labor.

13 ials to determine their efficacy in delaying preterm labor.

14 e treatment of hormone-sensitive cancers and preterm labor.

15 ected subclinical IAI in a human cohort with preterm labor.

16 ed risk of earlier preterm birth, PPROM, and preterm labor.

17 ying nitric oxide-donors in the treatment of preterm labor.

18 isolated from the amniotic fluid of women in preterm labor.

19 ly isolated from amniotic fluids of women in preterm labor.

20 nitiation of full-term labor and LPS-induced preterm labor.

21 ensitivity and positive predictive value for preterm labor.

22 lective COX inhibitors for the management of preterm labor.

23 e premature cervical changes associated with preterm labor.

24 n assessments of their symptoms and signs of preterm labor.

25 xalyl glycine (DMOG) to pregnant mice caused preterm labor.

26 nce to human pregnancy complications such as preterm labor.

27 n with complications of pregnancy, including preterm labor.

28 ssion increased in association with term and preterm labor.

29 on myometrial contractility in experimental preterm labor.

30 anes in women with CCA who underwent term or preterm labor.

31 nitiating event in both spontaneous term and preterm labor.

32 recurrent pregnancy loss, preeclampsia, and preterm labor.

33 rent spontaneous abortion, preeclampsia, and preterm labor.

34 and decreased clonal expansion in women with preterm labor.

35 el approach to prevent prematurity and treat preterm labor.

36 inflammation and increases susceptibility to preterm labor.

37 ene expression changes were also detected in preterm labor.

38 nterface (decidua) of women with spontaneous preterm labor.

39 ly used therapeutically for the treatment of preterm labor.

40 with or without labor at term and those with preterm labor.

41 play a critical role in processes of term or preterm labor.

42 contractile responsiveness, and the onset of preterm labor.

43 us and placenta during PGN+poly(I:C)-induced preterm labor.

44 anscription factor Hes1 were assessed during preterm labor.

45 us and placenta during PGN+poly(I:C)-induced preterm labor.

46 in utero infections, and the pathogenesis of preterm labor.

47 ations associated with fetal surgery such as preterm labor.

48 are growing in popularity but often lead to preterm labor.

49 ng the fetal period, as they are to women in preterm labor.

50 macrophages and did not independently induce preterm labor.

51 preterm delivery resulting from spontaneous preterm labor (10.2 percent vs. 3.5 percent; relative ri

52 14%]), cervical insufficiency (2 [14%]), and preterm labor (2 [14%]).

53 ike polarization during spontaneous term and preterm labor; 2) anti-inflammatory (M2)-like macrophage

54 ach delivery was classified by presentation: preterm labor (40%), prelabor premature rupture of membr

55 eceptor gamma (PPARgamma) during spontaneous preterm labor; 5) decidual macrophages from women who un

56 common in the second trimester (55.3%), and preterm labor (52.3%) and abnormal fetal heart rate moni

57 roach for the control of infection-triggered preterm labor, a condition for which there is no effecti

58 Spontaneous preterm labor, a syndrome caused by multiple pathologic

59 es, preterm birth is preceded by spontaneous preterm labor, a syndrome that is associated with intra-

60 s increased for infants delivered because of preterm labor (adjusted odds ratio (OR) = 2.3, 95% confi

61 a higher risk than those who delivered after preterm labor (adjusted odds ratio = 1.11, 95 percent co

62 sia (adjusted OR, 1.59 [95% CI, 1.54-1.63]), preterm labor (adjusted OR, 1.54 [95% CI, 1.50-1.57]), a

63 ith a glucocorticoid (dexamethasone, used in preterm labor), an organophosphate pesticide (chlorpyrif

64 ned from placental culture in a patient with preterm labor and acute chorioamnionitis.

65 e, in the mother, and in the fetus, inducing preterm labor and birth and adverse neonatal outcomes.

66 T cells, obtained from women with idiopathic preterm labor and birth displayed enhanced ex vivo activ

67 he NLRP3 inflammasome is a mechanism whereby preterm labor and birth occur in the context of microbia

68 lls are implicated in the pathophysiology of preterm labor and birth, the leading cause of neonatal m

69 human maternal-fetal interface of women with preterm labor and birth, which was confirmed by in silic

70 otic fluid of women who underwent idiopathic preterm labor and birth.

71 tor T cells in the mechanisms of disease for preterm labor and birth.

72 l invasion of the amniotic cavity leading to preterm labor and birth.

73 labor were mirrored by those in spontaneous preterm labor and birth.

74 adaptive immunity to the syndromic nature of preterm labor and birth.

75 ct maternal anti-fetal rejection, leading to preterm labor and birth.

76 ion and pathological inflammation leading to preterm labor and birth.

77 implicated in the pathogenesis of idiopathic preterm labor and birth.

78 s should remain focused on the prevention of preterm labor and BPD, novel research aimed at promoting

79 repertoire of decidual T cells in women with preterm labor and CCA have not been investigated.

80 ) has been implicated in the pathogenesis of preterm labor and clinical chorioamnionitis at term.

81 w transplant are likely to be accompanied by preterm labor and delivery of LBW or VLBW babies who do

82 um can identify women at risk for subsequent preterm labor and delivery.

83 Chorioamnionitis is associated with preterm labor and fetal inflammatory response syndrome (

84 he administration of carbamyl (c)-PAF caused preterm labor and fetal loss in wild-type mice but not i

85 th U. parvum infection in pregnancy, such as preterm labor and fetal sequelae.

86 ed with the birth of small babies (from both preterm labor and growth restriction), but so is failure

87 Preterm labor and infections are the leading causes of n

88 ed risk of adverse fetal outcomes, including preterm labor and intrauterine death.

89 A correlation between the onset of preterm labor and myometrial activation of the inflammat

90 inflammation, and may contribute to onset of preterm labor and other adverse perinatal outcomes.

91 bsequent effects on the better management of preterm labor and other inflammatory conditions.

92 ys a significant role in the pathogenesis of preterm labor and premature rupture of fetal membranes.

93 , and the clinical pathways involved include preterm labor and preterm premature rupture of membranes

94 Women with preterm labor and preterm premature rupture of membranes

95 um bile acids and complicated by spontaneous preterm labor and stillbirth.

96 mniocentesis after an episode of spontaneous preterm labor and subsequently delivered within 24 h (n

97 rm delivery without IAI, and in 0 of 11 with preterm labor and term delivery without infection (P<.00

98 quirement for infection/inflammation-induced preterm labor and that AP-1 activation is sufficient to

99 mmatory (M1) polarization during spontaneous preterm labor and that PPARgamma activation via rosiglit

100 macrophages are associated with spontaneous preterm labor and that PPARgamma activation via RSG can

101 e doubling of diparesis risk associated with preterm labor and with preterm premature rupture of feta

102 ous preterm birth (cases who had spontaneous preterm labor and/or preterm premature rupture of membra

103 taneous preterm birth presenting as PPROM or preterm labor, and it suggests that bleeding is less pre

104 f pregnancy, including spontaneous abortion, preterm labor, and low amniotic fluid volume at the time

105 estational diabetes, transplant dysfunction, preterm labor, and low birthweight infants.

106 rean delivery, length of stay, preeclampsia, preterm labor, and stillbirth.

107 loss in a mouse model of PAF-induced sterile preterm labor, and whether a small-molecule TLR4 inhibit

108 ty in amniotic fluid, increased incidence of preterm labor, and with decreased incidence of respirato

109 ophages from women who underwent spontaneous preterm labor; and 7) treatment with RSG reduces the rat

110 gestive heart failure (CHF), length of stay, preterm labor, anemia complicating pregnancy, placental

111 pre-eclampsia (aOR 1.18 [95% CI 1.02-1.36]), preterm labor (aOR 1.55 [95% CI 1.36-1.76]), chorioamnio

112 c pregnancy (aOR = 0.94, 95%CI = 0.73-1.20), preterm labor (aOR = 1.00, 95%CI = 0.92-1.10), gestation

113 d odds ratio [aOR], 3.18; 95% CI, 1.27-7.98; preterm labor: aOR, 2.18; 95% CI, 1.06-4.48), intrapartu

114 Women with arrested preterm labor (APTL) are at very high risk for spontaneo

115 Clinical GBS isolates obtained from women in preterm labor are hyperhemolytic and some are associated

116 However, the remaining etiologies of preterm labor are poorly understood; therefore, most pre

117 men at 13 North American centers who were in preterm labor at <30 weeks' gestation in a double-blind,

118 ernal stress and terbutaline (used to arrest preterm labor), autism risk factors in humans, on measur

119 2008 to February 2010, women with threatened preterm labor between 26 weeks (plus 0 days) and 32 week

120 gesterone can serve as a strategy to prevent preterm labor/birth and adverse neonatal outcomes by att

121 tor/activated T cells in the pathogenesis of preterm labor/birth is poorly understood.

122 sues is associated with noninfection-related preterm labor/birth.

123 ture preventative strategies for spontaneous preterm labor/birth.

124 matory response that accompanies spontaneous preterm labor/birth; however, their role is poorly under

125 nectin is associated with increased risk for preterm labor, but the influence of adiponectin on uteri

126 ffect of MCPT4 against GBS dissemination and preterm labor can be attributed in part to MCPT4-mediate

127 effects, including possible association with preterm labor, can be reduced by repeating colposcopy to

128 Preterm labor caused by uterine contractions is a major

129 arly-life factors, including maternal fever, preterm labor, cesarean delivery, and antibiotic or acid

130 Preterm labor commonly precedes preterm birth, the leadi

131 protected mice against inflammation-induced preterm labor, decreased baseline myometrial contractili

132 ophages from women who underwent spontaneous preterm labor display plasticity by M1<-->M2 polarizatio

133 sted odds ratio, 24.29; 95% CI, 7.48-78.81), preterm labor during current pregnancy (adjusted odds ra

134 for such outcomes are cervical incompetence, preterm labor during current pregnancy, vaginitis or vul

135 Repurposing simvastatin as a therapy for preterm labor: evidence from preclinical models.

136 ates for other problems, such as spontaneous preterm labor, fetuses small for gestational age, congen

137 d antenatal corticosteroids for mothers with preterm labor from 24 to 34 weeks' gestational age, but

138 tal anomaly, miscarriage, ectopic pregnancy, preterm labor, gestational diabetes mellitus, gestationa

139 Group 1, preeclampsia; Group 2, spontaneous preterm labor; Group 3, other maternal medical indicatio

140 The prevention and the treatment of preterm labor have been long-standing challenges.

141 actors such as bacterial vaginosis or during preterm labor have not consistently reduced the preterm

142 Most cases of preterm labor have unknown cause, and the burden of pret

143 mal models of infection/inflammation-induced preterm labor; however, inconsistencies in maternal and

144 of a PTB (HR: 0.84; 95% CI: 0.73, 0.95) and preterm labor (HR: 0.80; 95% CI: 0.69, 0.94).

145 sitive women also had a higher prevalence of preterm labor in a prior pregnancy (20.7%) than did the

146 causes spontaneous abortion, stillbirth, and preterm labor in humans and serves as a model for placen

147 the role of a2V during inflammation-induced preterm labor in mice and its relationship to the regula

148 nd physiological mechanisms of both term and preterm labor in primates.

149 ion into the repurposing of statins to treat preterm labor in women.

150 2 pregnant women with known risk factors for preterm labor (including 844 women who were pregnant wit

151 unity to evaluate the therapeutic benefit of preterm labor interventions on perinatal pathology.

152 tronidazole did not reduce the occurrence of preterm labor, intraamniotic or postpartum infections, n

153 molecular mechanisms involved in UTI-induced preterm labor involving bacterial adhesins.

154 We suggest that preterm labor is a polymicrobial disease, which requires

155 Spontaneous preterm labor is frequently caused by an inflammatory re

156 Preterm labor is the leading cause of neonatal death and

157 Although a link between infection and preterm labor is widely accepted, surprisingly little is

158 Preterm birth (PTB), often preceded by preterm labor, is a major cause of neonatal morbidity an

159 Spontaneous PTB, resulting from preterm labor, is commonly caused by intrauterine infect

160 o infection and are strongly associated with preterm labor, little is known about how human fetal imm

161 cidence of low birth weight (<2.5 kg) and of preterm labor (<37 completed weeks) occurs in associatio

162 ll and activated T-cell signatures) and with preterm labor (macrophage, monocyte, and activated T-cel

163 In threatened preterm labor, maintenance tocolysis with nifedipine, af

164 nistration of magnesium sulphate to women in preterm labor may aid in primary prevention of cerebral

165 IL-1 in amniotic fluid in preterm labor may promote lung maturation and thus be pa

166 een isolated from amniotic fluid of women in preterm labor, mechanisms of in utero infection remain u

167 via Rho/ROCK signaling, thus contributing to preterm labor-mediated preterm birth.

168 In murine inflammatory models of preterm labor, miR-203 overexpression prolongs pregnancy

169 nd aza-Phe-Pro analogs 2a and 2b in a murine preterm labor model featuring treatment with lipopolysac

170 In patients with threatened preterm labor, nifedipine-maintained tocolysis did not r

171 To identify the role of Notch signaling in preterm labor, Notch receptors (Notch1-4), its ligands (

172 A subsequent preterm labor occurred in 17 U. urealyticum-positive wom

173 se of labor triggers and hence contribute to preterm labor onset.

174 birth (ie, preterm birth that occurred after preterm labor or membrane rupture, without other complic

175 ch is elevated in pregnancies complicated by preterm labor or preeclampsia, triggers an inflammatory

176 ng cause of pregnancy complications, such as preterm labor or preeclampsia.

177 ntaneous," which was preceded by spontaneous preterm labor or preterm premature rupture of membranes,

178 , defined as preterm preceded by spontaneous preterm labor or preterm premature rupture of the membra

179 s increased for infants delivered because of preterm labor (OR = 2.7, 95% CI: 1.2, 5.7) and intrauter

180 ith an increase in odds of preterm delivery, preterm labor, or abortion by 23% (OR, 1.23; 95% CI, 1.1

181 ciated with higher odds of preterm delivery, preterm labor, or abortion compared with immediate opera

182 significant difference in preterm delivery, preterm labor, or abortion.

183 the placenta to cause spontaneous abortion, preterm labor, or significant disease in the surviving n

184 in progesterone production and a subsequent preterm labor phenotype.

185 Higher odds of cesarean delivery, preterm labor, poor fetal growth, or fetal distress were

186 study included normal delivery, miscarriage, preterm labor, preeclampsia, and stillbirth.

187 cental microbe recovery, was associated with preterm labor, prelabor premature rupture of membranes,

188 and PTBs and its clinical presentations (ie, preterm labor, premature rupture of membranes, and medic

189 es into 2 groups: intrauterine inflammation (preterm labor, preterm membrane rupture, placental abrup

190 s the presence/absence of MIAC in women with preterm labor (PTL) and intact membranes.

191 cularly associated with infection-associated preterm labor (PTL) in both women and mouse models.

192 Preterm labor (PTL) is the leading cause of neonatal mor

193 occurs in various diseases, but its role in preterm labor (PTL) is unknown.

194 on of uterine inflammatory pathways leads to preterm labor (PTL), associated with high rates of neona

195 f the following: gestational age < 37 weeks, preterm labor (PTL), or premature rupture of membranes (

196 and inflammation cause 30-40% of spontaneous preterm labor (PTL), which precedes PTB.

197 inflammation (IUI) is a major contributor to preterm labor (PTL).

198 injured women were also at increased risk of preterm labor (relative risk = 7.9, 95% confidence inter

199 he causes of pregnancy complications such as preterm labor requires greater insight into how the uter

200 ng is activated during PGN+poly(I:C)-induced preterm labor, resulting in upregulation of pro-inflamma

201 ers was associated with preterm birth due to preterm labor (RR = 3.6, 95% CI: 1.9, 6.8).

202 from preterm labor with intact (spontaneous preterm labor [sPTL]) or ruptured (preterm prelabor rupt

203 disease in pregnant women, which can lead to preterm labor, stillbirth, or severe neonatal disease.

204 s (GBS) transmission during pregnancy causes preterm labor, stillbirths, fetal injury, or neonatal in

205 of oxidative stress on membranes at term or preterm labor, term not in labor samples in an organ exp

206 In sterile preterm labor, the key regulators of inflammation are no

207 fection is a recognized cause of spontaneous preterm labor, the noninfection-related etiologies are p

208 taste receptors as targets for tocolytics in preterm labor therapy.

209 ulphate (MgSO4) are administered to women in preterm labor to reduce neurologic morbidity.

210 that the double hit of PGN+poly(I:C) induces preterm labor via reduction of a2V expression and simult

211 Preterm labor was associated with a decreased hazard of

212 mice injected with the PR antagonist RU486, preterm labor was associated with increased miR-200a, de

213 an amount of cervical dilatation at the time preterm labor was diagnosed (1.8 cm, 1.5 cm, and 1.4 cm,

214 points included cervical status at the time preterm labor was diagnosed and birth weight.

215 Preterm labor was initiated on gestation day 14.5 by int

216 Solving the mystery of preterm labor, which compromises the health of future ge

217 l effector memory T cell subsets in cases of preterm labor with CCA without altered regulatory T cell

218 nditions, including cancer-related cachexia, preterm labor with delivery, and osteoporosis.

219 ors may provide effective treatment to delay preterm labor with fewer adverse effects on fetal or neo

220 ster (n = 39), third trimester (n = 40), and preterm labor with intact (n = 131, 85 negative IAI and

221 rm birth occur spontaneously and result from preterm labor with intact (spontaneous preterm labor [sP

222 dverse cardiac event/outcome (aRR, 2.2), and preterm labor with preterm delivery (aRR, 1.2).

223 rs and whose mothers experienced spontaneous preterm labor without an infectious context and delivere

224 others (mean [SD] age, 29.2 [5.7] years) had preterm labor without fever and gave birth to 1320 child

225 undergoes premature activation in women with preterm labor without intra-amniotic inflammation, provi

226 events were preterm delivery (360 [35.4%]), preterm labor without preterm delivery (269 [26.4%]), an