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1 re estimated from STAR and the Breast Cancer Prevention Trial.
2 in women with anorexia nervosa in a relapse-prevention trial.
3 ls: the Wheat Bran Fiber Trial and the Polyp Prevention Trial.
4 us women within the Calcium for Preeclampsia Prevention trial.
5 f colorectal cancer, necessitating a primary prevention trial.
6 ovide a rationale for selenium breast cancer prevention trial.
7 ated in a subset of patients in the Fracture Prevention Trial.
8 xt of the recently completed Prostate Cancer Prevention Trial.
9 in rural KwaZulu-Natal within a treatment-as-prevention trial.
10 with the publication of the Prostate Cancer Prevention Trial.
11 sults with the impact of the Prostate Cancer Prevention Trial.
12 the Studies of Left Ventricular Dysfunction Prevention Trial.
13 cancer among all women in the Breast Cancer Prevention Trial.
14 y (HERS), a secondary coronary heart disease prevention trial.
15 5 mg) daily or to placebo in a secondary CHD prevention trial.
16 e Mammary Prevention.3 (MAP.3) breast cancer prevention trial.
17 fy participants closest to MCI for secondary prevention trials.
18 evaluating the efficacy of intervention and prevention trials.
19 ld be harnessed as an outcome measure for AD prevention trials.
20 be generally applicable to forthcoming bNAb prevention trials.
21 ew atopic dermatitis cases for use in future prevention trials.
22 served with antioxidant therapy in secondary prevention trials.
23 tudies and need to be assessed in randomised prevention trials.
24 y at-risk subjects for inclusion in diabetes prevention trials.
25 election of enriched patient populations for prevention trials.
26 e role of fibrillar Abeta imaging in primary prevention trials.
27 pregnancies and power the design of clinical prevention trials.
28 st HIV-1 are currently being tested in HIV-1 prevention trials.
29 o the statistical power and integrity of HIV prevention trials.
30 lenges of human immunodeficiency virus (HIV) prevention trials.
31 istical power and calculated outcomes of HIV prevention trials.
32 g patients' decisions about participation in prevention trials.
33 cruitment of patients with SLE into clinical prevention trials.
34 ofessional surveillance, or participation in prevention trials.
35 ologic studies and polyp recurrence in polyp-prevention trials.
36 otential for benefit from large-scale cancer prevention trials.
37 of mortality at levels similar to secondary prevention trials.
38 the populations represented in these primary-prevention trials.
39 oxicity for the coxibs in adenoma recurrence prevention trials.
40 ed by 48% (36-58; p<0.0001) in the tamoxifen prevention trials.
41 er in other animal models or in human cancer prevention trials.
42 ents and death in both primary and secondary prevention trials.
43 ced by both primary prevention and secondary prevention trials.
44 p reduce the risk of pregnancy in future HIV prevention trials.
45 -informed prioritization of drug targets for prevention trials.
46 Alzheimer disease (AD) for enrollment in AD prevention trials.
47 cally and methodologically heterogeneous CVD prevention trials.
48 r the success of recently launched secondary prevention trials.
49 coronary heart disease event in the primary prevention trials.
50 ross all trials, and within intervention and prevention trials.
51 increasingly being targeted for AD secondary prevention trials.
52 subjects at high risk of type 1 diabetes to prevention trials.
53 , contributing to lower recruitment rates in prevention trials.
54 set, and helpful for forthcoming therapeutic prevention trials.
55 ical intervention and be good candidates for prevention trials.
56 es also suggest the feasibility of secondary prevention trials.
57 isk factors and in research-driven clinical (prevention) trials.
58 meta-analysis of 23 407 patients in primary prevention trials (0.52%): 0.74% with rofecoxib (P =.04
60 including coronary death or MI) for primary prevention trials (1.5% lower event rate [95% CI, 0.5%-2
61 Strong African American Families randomized prevention trial, 119 right-handed African American indi
62 54 serious vascular events) and 16 secondary prevention trials (17,000 individuals at high average ri
63 ong participants (n = 1,905) in the US Polyp Prevention Trial (1991-1998) on colorectal adenoma recur
70 c hyperplasia (BPH) in 4,770 Prostate Cancer Prevention Trial (1994-2003) placebo-arm participants wh
73 cipated in the Selenium and Vitamin E Cancer Prevention Trial (2001-2011) with present analyses compl
74 tty acids (SU.FOL.OM3) trial was a secondary prevention trial (2003-2009; n = 2501) in which individu
75 L lower LDL-C level; P = .008) and secondary prevention trials (4.6% lower event rate [95% CI, 2.9%-6
77 cular death) and major bleeds in six primary prevention trials (95,000 individuals at low average ris
78 of a randomized controlled trial, the Polyp Prevention Trial, a higher intake of one subclass, flavo
79 participated in the Calcium for Preeclampsia Prevention trial, a randomized study of nulliparous wome
82 , 2012, from among children attending an AOM prevention trial and children visiting local outpatient
84 ar diagnostic technique has implications for prevention trials and for the early diagnosis of HCC.
85 ese differences may inform findings from HIV prevention trials and future implementation of antiretro
87 omposite endpoints in venous thromboembolism-prevention trials and provide rationale for de-escalatio
88 bridge the gap between primary and secondary prevention trials and specifically included patients wit
89 uld improve subject selection into secondary prevention trials and visual assessment in clinical rout
90 Study II, the Selenium and Vitamin E Cancer Prevention Trial, and a European study, Supplementation
91 nseling and testing and enrolled in an HIV-1 prevention trial, and index participants had a baseline
92 rs leading to an international breast cancer prevention trial, and insights into the intricate germli
93 sment, intermediate outcome determination in prevention trials, and regulation of tobacco products.
94 ether Tenofovir (TFV), used vaginally in HIV prevention trials, and Tenofovir alafenamide (TAF), an i
95 targeted communities or clinicians, primary prevention trials, and trials that reported events of no
100 analyses of 2 randomized controlled primary prevention trials (ASCOT [Anglo-Scandinavian Cardiac Out
103 cebo group (n = 9457) in the Prostate Cancer Prevention Trial at 221 US centers were evaluated every
104 and Bowel Project (NSABP) P-1: Breast Cancer Prevention Trial (BCPT) demonstrated the superiority of
105 cancer prevention trials, the Breast Cancer Prevention Trial (BCPT) of tamoxifen and Prostate Cancer
106 ecular targets for chemoprevention, clinical prevention trials, behavioral prevention research, publi
107 spirin versus control in primary (Thrombosis Prevention Trial, British Doctors Aspirin Trial) and sec
108 efined, referral into screening programs and prevention trials can be better targeted to reach famili
111 3.27; P = 8.4 x 10(-5)) in the Wuhan Smoking Prevention Trial cohort, and they replicated the associa
113 s with individual participant data from nine prevention trials comparing four selective oestrogen rec
115 trial cancer were increased in all tamoxifen prevention trials (consensus relative risk 2.4 [1.5-4.0]
116 42; 95% CI, 0.29-0.55; P < .001) relative to prevention trials (d = 0.07; 95% CI, -0.13 to 0.28; P =
120 tastatic or advanced cancer; complexities of prevention trial design; a relatively uncharted Food and
121 STAR was a double-blind, randomized phase 3 prevention trial designed to evaluate the relative effic
122 ong screened men enrolled in prostate cancer prevention trials, differences in risk factor estimates
127 prospective end point in long-term secondary prevention trials evaluating the risks and benefits of a
128 Using evidence from a randomized depression prevention trial for older adults, the authors found tha
129 equisite for enrollment in several secondary prevention trials for AD, yet the precise effect of elev
133 ive or universal) and treatment or indicated prevention trials (for children diagnosed or above the c
134 atic Alzheimer's disease to join the ongoing prevention trials, for which mAbs continue to serve as t
136 ; 216 total deaths) from exclusively primary prevention trials found a significant reduction in prima
140 outcome in clinical trials and toxicity in a prevention trial have shifted focus away from these cycl
141 Observational cohort studies and a secondary prevention trial have shown an inverse association betwe
142 ividuals who are likely to enroll in primary prevention trials have a high socioeconomic status, heal
144 large-scale Alzheimer disease (AD) secondary prevention trials have begun to target individuals at th
148 population-based, Phase III prostate cancer prevention trials have shown a significant benefit for 5
149 Washington Virology Research Clinic) and HIV prevention trials (HIV Prevention Trials Network 039 and
151 man Immunodeficiency Virus (HIV) Network for Prevention Trials (HIVNET) 012 trial in Uganda, 6-8 week
153 as a secondary risk marker and in secondary prevention trials (ie, with folate/B vitamins) to determ
154 or interpreting the results of ongoing HIV-1 prevention trials.IMPORTANCE HIV remains a major public
155 land Coronary Prevention Study was a primary prevention trial in 45- to 64-year-old men with high low
156 's Prevention Initiative Generation Study, a prevention trial in cognitively unimpaired APOE-e4/e4 ho
157 cotland Coronary Prevention Study, a primary prevention trial in hypercholesterolemic men) exhibited
158 minished since the publication of the Stroke Prevention Trial in Sickle Cell Anemia (STOP trial) in 1
162 pants enrolled in the RESPECT study - an HIV prevention trial in Tanzania that used cash awards to in
164 s a longitudinal, randomized atherosclerosis prevention trial in which repeated dietary counseling ai
166 volved a review of the primary and secondary prevention trials in calcineurin inhibitor withdrawal.
175 uvant Breast and Bowel Project Breast Cancer Prevention Trial indicate that tamoxifen can reduce the
177 nd the Multi-Domain Intervention Alzheimer's Prevention Trial (MAPT-18F AV45-PET; n = 23) cohorts.
184 An interim analysis of data from the HIV Prevention Trials Network (HPTN) 052 trial showed that a
188 81% ART coverage target, as part of the HIV Prevention Trials Network (HPTN) 071 Population Effects
191 earch Clinic) and HIV prevention trials (HIV Prevention Trials Network 039 and Partners in Prevention
192 mmunodeficiency virus (HIV) acquisition (HIV Prevention Trials Network 039), acyclovir had a smaller
194 ssion of HIV infection and data from the HIV Prevention Trials Network 052 study, we projected the co
195 uples and a randomized controlled trial (HIV Prevention Trials Network 052) show that antiretroviral
197 ersal ART initiation was provided in the HIV Prevention Trials Network 071 (PopART) trial in South Af
202 ative study, a randomized controlled primary prevention trial of 14 749 postmenopausal asymptomatic w
206 d that it is feasible to conduct a secondary prevention trial of periodontal therapy in patients who
207 ntion Trial Evaluating Rosuvastatin) primary prevention trial of rosuvastatin 20 mg compared with pla
208 g double-blind, placebo-controlled secondary prevention trial of the benefits and risks of antioxidan
212 subgroup analysis of the major CHD secondary prevention trials of lipid-lowering with regard to the b
216 ide Randomized Antibiotic Envelope Infection Prevention Trial) offers an opportunity to evaluate the
219 le-blind, placebo-controlled, primary cancer prevention trial; participants were Finnish male smokers
220 nasteride or placebo) of the Prostate Cancer Prevention Trial (PCPT) and from clinically localized pr
222 rial (BCPT) of tamoxifen and Prostate Cancer Prevention Trial (PCPT) of finasteride, concluded with s
225 ndomized trials, such as the Prostate Cancer Prevention Trial (PCPT), Reduction by Dutasteride of Pro
226 the finasteride group of the Prostate Cancer Prevention Trial (PCPT), we evaluated the impact of pros
227 te cancer prevention trials (Prostate Cancer Prevention Trial [PCPT] and Selenium and Vitamin E Cance
228 Initiative, a randomized controlled primary prevention trial (planned duration, 8.5 years) in which
231 actors in a multicenter, randomized, primary-prevention trial (PREDIMED-Plus) based on an intensive w
233 he placebo arms of two large prostate cancer prevention trials (Prostate Cancer Prevention Trial [PCP
234 mmunity is initiated in infancy, and primary prevention trials require children at high genetic risk
236 umber of incident pregnancies may render HIV prevention trial sample sizes inadequate by as much as 5
237 trial size, duration, and cost--of enriching prevention trial samples by combining clinical informati
240 report of the Selenium and Vitamin E Cancer Prevention Trial (SELECT) found no reduction in risk of
241 he large-scale Selenium and Vitamin E Cancer Prevention Trial (SELECT) showed that antioxidants faile
242 er risk in the Selenium and Vitamin E Cancer Prevention Trial (SELECT) through unknown mechanisms whi
243 cillary to the Selenium and Vitamin E Cancer Prevention Trial (SELECT), a randomized clinical trial o
244 CE) trial, and Selenium and Vitamin E Cancer Prevention Trial (SELECT), have provided practitioners w
245 cancer in the Selenium and Vitamin E Cancer Prevention Trial (SELECT), plays an integral role in thy
247 design of the Selenium and Vitamin E Cancer Prevention Trial (SELECT; testing vitamin E and selenium
248 trolled trial (Selenium and Vitamin E Cancer Prevention Trial [SELECT]) of 35,533 men from 427 partic
249 ial [PCPT] and Selenium and Vitamin E Cancer Prevention Trial [SELECT]) were examined to define incid
253 Another large, Phase III prostate cancer prevention trial showed no benefit for either selenium o
254 n con Dieta Mediterranea) randomized primary prevention trial showed that a Mediterranean diet enrich
257 important to consider in upcoming secondary prevention trials targeting CN individuals at high risk
258 ng the possibility of early intervention and prevention trials, targeting MCI and cognitively healthy
259 ed, double-blind, placebo-controlled primary prevention trial testing the effects of beta-carotene an
261 has been demonstrated by the Prostate Cancer Prevention Trial that a chemoprevention strategy using a
262 aluating Rosuvastatin), a randomized primary prevention trial that compared rosuvastatin treatment to
263 ticle reviews multiple secondary and primary prevention trials that have expanded the indications for
269 rrent adenoma during the course of the Polyp Prevention Trial to determine baseline concentrations of
270 te the feasibility of a randomized secondary prevention trial to test whether treatment of periodonta
271 We used data from venous thromboembolism prevention trials to evaluate the causal effect of venou
272 children with ADHD sets the stage for early prevention trials to reduce risk for later depression an
273 consider in deciding about participating in prevention trials, to uncover concerns about SLE trials,
274 rimary end point were analyzed: the Diabetes Prevention Trial-Type 1 (DPT-1) and the TrialNet oral in
275 alleles among individuals from the Diabetes Prevention Trial-Type 1 (DPT-1) clinical trial, which te
277 Among those at high risk (with a Diabetes Prevention Trial-Type 1 Risk Score [DPTRS] >=6.75), the
278 n trial progressors to T1D from the Diabetes Prevention Trial-Type 1 with at least one FPIR measureme
279 ng 9,559 participants in the Prostate Cancer Prevention Trial (United States and Canada, 1994-2003).
282 may be one reason why cardiovascular disease prevention trials using these vitamins have reported con
285 d to determine eligibility for breast cancer prevention trials was greatly increased relative to prev
286 y outcome-related analysis from a randomized prevention trial, we examined the long-term influence of
288 Participants in the double-blind primary prevention trial were randomly assigned to receive 40 mg
289 ND METHODS Raw data from the Prostate Cancer Prevention Trial were used to model chemopreventive trea
292 se nevirapine from a Ugandan perinatal HIV-1 prevention trial when 496 babies were followed up to age
293 ons could be useful in active-controlled HIV prevention trials where low HIV incidence is expected.
294 ol study within the Calcium for Preeclampsia Prevention trial, which involved healthy nulliparous wom
295 tate cancer among men in the Prostate Cancer Prevention Trial who had a PSA level of 4.0 ng per milli
296 ects who would benefit from participation in prevention trials who have one islet antibody by traditi
297 y published results from the Prostate Cancer Prevention Trial: Who are the best candidates for finast
300 Chinese Han population in the Wuhan Smoking Prevention Trial (Wuhan, China, 1998-1999), the authors