ライフサイエンスコーパス: previously

1 nd not just in the extinction or reversal of previously acquired learning, as previously thought.

2 ons of high indole concentration if they had previously adapted to indole but were otherwise repelled

3 We previously addressed this challenge by developing time-s

4 AC injection, disease grouping at diagnosis, previously administered treatments, number of IAC inject

5 prominent role during brain development than previously anticipated.

6 with quaternary detection (GPC-4D) has been previously applied to other polymers, and the relevant m

7 r cells, calling for reassessment of results previously ascribed to STAT3 functions.

8 We previously assessed indoor and personal air pollution ex

9 ble to assign the NMR shifts with the aid of previously assigned solution-state shifts for the RRM2,3

10 otably GM(3) gangliosides) and lipid classes previously associated with cardiometabolic disease (phos

11 ysiological reactivity, whereas some regions previously associated with metacognition and conscious p

12 ave shown that incidence is much higher than previously assumed and that the majority of patients nev

13 ciple of the anuran dopaminergic system than previously assumed.

14 ling spatiotemporal dynamics undetectable by previously available methods.

15 This has previously been attributed to molecular memory and, more

16 restige' was the number of times someone had previously been copied by others.

17 for ethnic minorities and the uninsured have previously been demonstrated; however, outcomes in undoc

18 inum chemotherapy in lung adenocarcinoma has previously been hampered by inappropriately tailored in

19 vin A and GluN2B-containing NMDARs have both previously been implicated in hippocampal synaptic plast

20 ulator of NF-kappaB signaling that has never previously been linked to density-dependent proliferatio

21 Heart failure has previously been linked to sleep disorders that are often

22 onal higher order oligomerisation, which has previously been predicted to be important for Rheb-signa

23 Such near-freezing temperatures have not previously been reconstructed from proxy data for anywhe

24 pes of cells, including neurons, but has not previously been shown to form such an organized factory

25 tion of EGFR signaling in the ALA neuron has previously been suggested to promote sleep independently

26 8 seropositive participants, 433 (64.8%) had previously been tested for SARS-CoV-2 RNA, and 50.0% had

27 Spontaneous blink rate (SBR) has previously been used to measure stress responses in huma

28 Previously, Bode's chiral acylated hydroxamic acids were

29 y been used for hydroaminations and have not previously catalyzed such reactions with unactivated alk

30 racterized here include 13 that had not been previously characterized and that collectively explain a

31 We selected 24 diverse samples from a previously characterized data set derived from DNA extra

32 The previously characterized noncoding RNA that regulates ex

33 o not encode any discernable similarities to previously characterized sequences were identified.

34 A previously characterized version of Cdc42p, Cdc42p(E100A

35 dentified genes encoding known receptors for previously characterized viruses of Escherichia coli (ph

36 concentration of bicarbonates in water than previously considered at conditions relevant to the Eart

37 s nested within annotated ORFs and from RNAs previously considered noncoding, it is becoming clear th

38 ooked by the scientific community, as it was previously considered to be an artifact of a dysfunction

39 cell line HCT-116 and observed overlap with previously curated LADs.

40 by noncanonical mechanisms unrelated to the previously cytotoxic properties attributed to HDAC inhib

41 l connectivity among 12 regions comprising a previously defined spatial network were evaluated.

42 upregulation of the ACE2/Ang1-7/Mas axis and previously demonstrated benefits of lung function improv

43 belief, PIK3CA mutations have also not been previously demonstrated in this tumor entity.

44 We previously demonstrated that a sharp drop in Tie2 expres

45 We have previously demonstrated that both adiponectin and AdipoR

46 We have previously demonstrated that both GLP-1 and CCK are prod

47 We have previously demonstrated that copper dependent inhibitors

48 We previously demonstrated that nervonic acid, a C24:1 omeg

49 We previously demonstrated that RSPOs 2 and 3 potentiate WN

50 ococcus aureus, and Escherichia coli We have previously demonstrated that sphingosine is present in n

51 We have previously demonstrated that toll-like receptor 2 (TLR2)

52 se findings also provide a rationale for the previously described "olfactory lens," an increase in ph

53 We previously described an exceptional period of viral cont

54 e combined use of two novel antigens and one previously described antigen provided 96% sensitivity an

55 ing of the patient showed HLA-DQ8, which was previously described as SHP-sensitive.

56 ition of PAX occupancy that accounts for all previously described features of PAX inhibition, includi

57 opts a distinct conformation not observed in previously described RSV G-antibody structures.

58 We have previously described that tailoring the rate-response pr

59 We previously described the H3.3K27M mutation as a shared n

60 We previously described the regulatory events that control

61 profiles and far greater heterogeneity than previously described.

62 embly of Abeta oligomers, our laboratory has previously designed and synthesized macrocyclic peptides

63 ly, almost half of the interactions were not previously detected by two-hybrid or AP-MS techniques.

64 ile m(6)A-modified adenoviral RNAs have been previously detected, the location and function of this m

65 To advance XL-MS studies, we have previously developed a series of sulfoxide-containing MS

66 We have previously developed agents incorporating spiropyran der

67 We compared these reference values with previously developed equations for AEX (by gender and ra

68 We validated the previously developed PREDICT scoring tools for stratifyi

69 The RLPM assay, and a previously developed RLEP quantitative polymerase chain

70 Previously diagnosed partners with no report of CD4 coun

71 es data should inform engagement in care for previously diagnosed partners.

72 However, recombinant IL-18 previously did not demonstrate efficacy in clinical tria

73 of disturbance (no management, restoration [previously disturbed], and disturbance [currently distur

74 implementing strategies across the cities at previously documented scale-up reached $559 million per

75 ed protocadherin, an elongated particle with previously elusive views.

76 d by the G protein fusion loops that has not previously emerged as a target for neutralizing antibodi

77 To overcome this deficiency, we have previously employed computational approaches to deduce g

78 We have previously engineered a synthetic DNA vaccine targeting

79 In doing so, we are able to retrieve both previously established and novel biologically relevant p

80 micro-embolic agent Lipiodol, which has been previously established as an imaging biomarker for tumor

81 Not only are previously established modifications observable by mass

82 tcome was set according to six grades with a previously established prognostic ordinality: grade 1 =

83 We have previously established that the Med1 Mediator subunit se

84 ading from RBCs was considerably slower than previously estimated in acellular hemoglobin solutions,

85 f glycine embedded within nontronite samples previously exposed to either acidic or alkaline fluids (

86 s such as giant tear, chronic RD, or RD with previously failed surgery.

87 invasive predators were eradicated ~11 years previously, FID was also higher than on islands with no

88 placed Rohingya settled in informal sites on previously forested land, in areas without basic infrast

89 of these lineages and examined for outcomes previously found to be altered by Pb, PS, or combined Pb

90 Bermekimab, previously found to be effective in treating HS, was eva

91 nhibition can enhance antiangiogenic therapy-previously found to be ineffective in patients with TNBC

92 baseline anti-GBS levels, postdose 2 GMCs in previously GBS-vaccinated women exceeded postdose 1 GMCs

93 We analyzed previously generated single-cell RNA-sequencing (scRNA-s

94 ediatric admissions with sepsis (6,300 [33%] previously healthy and 12,813 [67%] with a chronic disea

95 Severe COVID-19 is rare in previously healthy individuals who are less than 50 year

96 tion, the majority of those hospitalized are previously healthy infants.

97 A 71-year-old, previously healthy male presented 6 h post apparently un

98 We found that those females previously housed with sterile males also showed enhance

99 We previously identified a novel cullin-RING E3 ligase util

100 We previously identified a nuclear myocardin-related transc

101 s of similar magnitude to ATP, including the previously identified agonists ATPgammaS and ATPalphaS,

102 artner of CDKB1;1, via SIM motif A, which we previously identified as a CDK-binding motif.

103 Previously identified B. burgdorferi proteins, lipid imm

104 dicted patient survival more accurately than previously identified cancer biomarkers.

105 not only provided evidence for reconciling a previously identified conflicting phenotype but also rev

106 dues involved in amidase activation map to a previously identified groove in the EnvC LytM domain tha

107 ng the estrogen receptor alpha (ERalpha) was previously identified in a female patient with estrogen

108 compared Binner annotations of 75 compounds previously identified in human plasma samples with annot

109 We and others have previously identified novel eNOS interactors, including

110 l RNA processing and protein production, but previously identified substrates of the redirected ligas

111 d biological function, and provide roles for previously identified UAF domains that include the Rrn5

112 We previously identified wheat gene WFhb1-1 (aka WFhb1-c1)

113 uroticism), as well as SARM1, which has been previously implicated in axonal degeneration (p = 1.76 x

114 any immune receptors in mammals, but was not previously implicated in IL-17 signaling or nervous syst

115 While RL has been used effectively previously in idealized computer flow simulation studies

116 These technologies have enabled previously inaccessible chemical transformations and hav

117 g the effects of EFs and providing access to previously inaccessible EF regimes.

118 room temperature as well as a large range of previously inaccessible Ullmann-Goldberg coupling produc

119 s illuminate base editing, enable editing at previously intractable targets, and provide new base edi

120 or of HSV-1 release, syndecan-1 has not been previously investigated in HSV-1 release.

121 yifB, yfaT and ynfE), as well as recovering previously known cases (in sigK, spsM, comK, mlrA and hl

122 Rhombencephalosynapsis has no previously known definitive genetic or environmental cau

123 in phosphorylating these sites, including 7 previously known to function in the clock.

124 c3) is a member of the alpha-arrestin family previously linked to human obesity.

125 e sea-level forcing is more complicated than previously modelled(1,2,6).

126 vaccinated women exceeded postdose 1 GMCs in previously non-GBS-vaccinated women (>=7-fold).

127 stable formation in the solid state that has previously not even been suggested.

128 d expands gene editing to chromosomal tracts previously not possible to modify seamlessly due to thei

129 m studies was considered responsible for the previously noted genetic difference.

130 Besides previously observed correlations attributed to particula

131 In view of the complex photoreactivity previously observed for dyads containing BP covalently l

132 contrasting with flagellin-only homopolymers previously observed in exoflagellated bacteria.

133 ubiquitous SAG1 to rare surface antigens not previously observed in tachyzoites.

134 Previously observed racial and sex disparities in living

135 ast DNA inserted into a mouse chromosome was previously observed to adopt a mitotic organisation dist

136 ophy (nGA) describes features on OCT imaging previously observed to precede the development of atroph

137 human fetal brain atlas was developed using previously obtained MRI imaging of 81 healthy fetuses be

138 gest a defensive strategy against predation, previously only known from trilobites preserved in open-

139 eristic mitotic somal translocation behavior previously only observed in human development, suggestin

140 Previously, our laboratory implicated the histone demeth

141 These compounds, together with a number of previously prepared HS oligosaccharides, were printed as

142 hus, in stark contrast to numerous functions previously proposed for Doc2, here we find that Doc2b re

143 ades and body plans, but not concurrent with previously proposed periods of adaptive radiation.

144 ase (FMO) produced by A. sativum (AsFMO) was previously proposed to oxidize S-allyl-l-cysteine (SAC)

145 ere not deeper-rooted than trees as had been previously proposed; and (3) evergreen trees had the dee

146 We combined analysis of previously published blood transcriptomic data with new

147 Previously published comparative functional genomic data

148 Based on a comparison with previously published data, HuNoV exhibited similar UV(25

149 ical samples diagnosed and confirmed using a previously published duplex real-time PCR (capable of de

150 Contrary to preregistered predictions and to previously published findings, MHC heterozygosity was no

151 Findings were analyzed relative to previously published ganglion cell distributions in this

152 al framework that significantly improves the previously published LeafCutter in the context of detect

153 11 kcal/mol, comparable with the accuracy of previously published state-of-the-art small-molecule rel

154 her differences whose magnitude has not been previously quantified in three independent human cohorts

155 To address this situation, we previously quantified interactions of alkyl ureas with a

156 reported by 7 (2.8%) patients, 6 of whom had previously received DEX.

157 We have previously reported a rat carrying a TUBB4A (A302T) muta

158 We previously reported an in vivo gain-of-function screen t

159 Furthermore, previously reported associations of IgG Fc glycosylation

160 Comparing this to previously reported CFC-11 emissions estimated for earli

161 Our analyses confirm previously reported drivers(6,7), raise doubts about oth

162 of neutral lipids and phospholipids resemble previously reported effects on lipid homeostasis in othe

163 MTG16 also bound to previously reported enhancer regions of genes regulated

164 Here, we review previously reported enzyme kinetic parameters of cellula

165 In conclusion, we confirmed several previously reported epitopes but also identified novel (

166 Our previously reported finding that protein cysteine oxidat

167 Curie temperature (75 K), values larger than previously reported for any monolayer oxides are observe

168 omain-independent manner, in contrast to the previously reported Hsc70-Hsp105-SGTA-Bag2 cytosolic com

169 after-hyperpolarization, similar to what we previously reported in dentate gyrus neurons.

170 We consolidate previously reported interpretations regarding the local

171 amined computationally and compared with the previously reported Ni congener, [K(2.2.2-cryptand)][(tB

172 ted proteins TAB1 and Polyhomeotic confirmed previously reported O-GlcNAc sites in TAB1 (S395 and S39

173 d micrometer-size organic phases rather than previously reported ordered gradients in C functional gr

174 hich are both the highest values compared to previously reported pure Ti(3) C(2) T(x) films.

175 ccount for the large discrepancies among the previously reported spin Hall angle values and reveal th

176 We previously reported that adiponectin acts in the brain t

177 HPVs infect human keratinocytes, and we previously reported that both PTPN14 degradation by HPV1

178 We have previously reported that Glrx knockout mice had increase

179 We previously reported that metastatic pancreatic cancers w

180 We have previously reported that Roundabout (Robo) receptors are

181 We previously reported that the valosin-containing protein

182 ith acylsugar accumulation, except two genes previously reported to be involved in acylglucose biosyn

183 es exhibits a T(c) significantly higher than previously reported values (ca. 150 K), reaching a maxim

184 n extraordinary finding that outperforms any previously reported values for MOF-based systems.

185 As previously reported, immunocompetent Tg(+) juveniles exh

186 me of the identified loci matched with those previously reported, we present additional association s

187 sis of serrulatane diterpenoids has not been previously reported.

188 ered from larger variety of pathologies than previously reported.

189 which WNT signalling dysregulation has been previously reported.

190 ), comparing DN variant frequencies with 777 previously sequenced unaffected trios.

191 ghtly controlled to avoid aneuploidy, and we previously showed that active Ran coordinates ring posit

192 We previously showed that AVM-brain endothelial cells (BECs

193 crowding as a well-controlled challenge, we previously showed that no classic model of vision, inclu

194 We previously showed that Rickettsia australis activates AS

195 (99m)Tc-PHC-102 has previously shown favorable in vivo biodistribution prope

196 We have previously shown that in male mice transient blockade of

197 We have previously shown that TBX1 is required for systemic lymp

198 We have previously shown that the ts residue signature of the Ru

199 We have previously shown that this effect of leptin is mediated

200 We have previously shown that transient acetylation of the glyco

201 We have previously shown that venlafaxine reduces PNN deposition

202 We show that RHT/AGIL, previously shown to interact with CNBP, contains a highl

203 erine protease tissue plasminogen activator, previously shown to potentiate NMDAR activity, induces m

204 olyethylene glycol (PEG) of 20 to 40 kDa was previously shown to prolong the residence time of rhDNas

205 In contrast to the previously solved ESX-5 heterotrimers, the PE-PPE hetero

206 s of free anionic nucleobases and base pairs previously studied only computationally and in the gas p

207 The majority of Env trimers of most previously studied SHIVs, however, do not recapitulate k

208 the larger context of outer retinal atrophy, previously suggested as a new form of advanced AMD, and

209 regulatory sequence is much more common than previously suspected, with enhancers sometimes located m

210 Previously, SWI/SNF chromatin remodeling was found to de

211 1 recapitulates myriad aneuploidy signatures previously taken as eukaryotic responses.

212 It was shown previously that a change in receptor specificity is a ha

213 We have reported previously that a region of tau (297-391), referred to a

214 reversal of previously acquired learning, as previously thought.

215 mediate the attraction of neutrophils, shown previously to allow transfer of nucleotides across membr

216 r resistance (PVR) 2.2 to 3.0 WU, considered previously to be normal, appears to associate with eleva

217 s close monitoring for allo-sensitization in previously tolerant transplant recipients in whom tolera

218 izumab (an anti-PD-1 monoclonal antibody) in previously treated patients with HER2-positive gastro-oe

219 with HER2-positive metastatic breast cancer previously treated with trastuzumab, pertuzumab, and tra

220 cal apical targeting sequence that maps to a previously unannotated region of the scaffold.

221 These data reveal a previously unappreciated contribution of dual TCR cells

222 Ha and colleagues describe a previously unappreciated diversity of microbes in the me

223 ms can arise from the neocortex and reveal a previously unappreciated interplay between brain state p

224 Thus, the IGF system represents a previously unappreciated pathway by which type 3 immunit

225 rogression based on selectively disrupting a previously unappreciated signaling cascade.

226 two dissipative pathways, one of which is a previously uncharacterized chlorophyll-to-carotenoid ene

227 tructure-guided sequence analysis we uncover previously uncharacterized CIF peptides conserved among

228 Here we show that a previously uncharacterized gene, ENLARGED VESSEL ELEMENT

229 fore, TrkB signaling is a key regulator of a previously uncharacterized neuronal population within th

230 In conclusion, we identified a previously uncharacterized population of extrafollicular

231 essfully predict the bipotent phenotype of a previously uncharacterized population of peritoneal baso

232 In doing so, we identified and validated previously uncharacterized RBPs that modulate stress gra

233 HIII, Bacillus subtilis NCIB 3610 encodes a previously uncharacterized RNase HI protein, RnhP, on th

234 These data indicate a previously underappreciated role for the relatively unex

235 dentify trends in AMR mobility and determine previously undescribed and novel resistance variants.

236 loci neighborhoods for the identification of previously undescribed anti-defense systems.

237 nded genetic repertoires include diverse and previously undescribed CRISPR-Cas systems, transfer RNAs

238 Here, to identify previously undescribed genes associated with development

239 This discovery of POLGARF unveils a previously undescribed mechanism of de novo protein-codi

240 Some appear to be the result of previously undescribed recombination events between ssDN

241 lutaric dehydrogenase complex can exist as a previously undiscovered hybrid containing DHTKD1 display

242 Our study reveals a previously undiscovered Lyn-dependent exit route of flav

243 ence of Trem2-dependent DAM and identified a previously undiscovered Serpina3n(+)C4b(+) reactive olig

244 be clinically beneficial in differentiating previously unexploitable narrow physiologic differences.

245 Our analysis identifies several previously unexplored candidate blood biomarkers of neur

246 ooming and regurgitated food donations among previously unfamiliar captive vampire bats (Desmodus rot

247 ionine sulfoxide reductase Mxr1 (MsrA) and a previously unidentified cytoplasmic pool of the reductas

248 The previously unidentified fraction was highest among men (

249 ese results demonstrate the existence of two previously unidentified interactions: one between A33 an

250 (18)F-FDG PET/CT detected previously unidentified metastases in 8 (38%) of 21 pati

251 Agd3 homologues are encoded in previously unidentified putative bacterial exopolysaccha

252 quent retention of RNAP on DNA constitutes a previously unidentified stage, termed here as recycling.

253 m, an expression of beak morphology that was previously unknown among Mesozoic birds and is superfici

254 Our findings indicate a previously unknown assembly pathway and inspire a sugges

255 The constitutive equation also reveals previously unknown ballistic and diffusive limits for ma

256 ly to increase, indicating the presence of a previously unknown degree of functional compensation in

257 Domain swap chimeras also revealed previously unknown functional differences in the GTPase

258 and archaeal genomic families and nearly 300 previously unknown genera, many potentially endemic to t

259 also report the characterization of several previously unknown halophilic viruses, many of which exh

260 Based on the data and the isolation of two previously unknown heterocyclophanes, we outline a unifi

261 We identified seven previously unknown inhibitors of GMII from a library of

262 predicted to occur in plants, and identified previously unknown interactions conserved over 1.1 billi

263 Vpr counteracts a previously unknown macrophage-specific restriction facto

264 ode has consequently been deemed to reveal a previously unknown major tropical eruption in 1108 CE.

265 adenine nucleotide translocase 3 (ANT3) as a previously unknown mortalin substrate and cell survival/

266 identify pathway communities and hundreds of previously unknown pathway contacts that represent poten

267 's Discriminant Analysis methods to identify previously unknown positive and negative genetic contrib

268 ision neuroimaging and arm casting to unmask previously unknown pulses of spontaneous activity.

269 Here, we provide evidence for a previously unknown quality control mechanism in which th

270 These findings suggest a previously unknown role for myocardial trabeculae in the

271 Despite the promise of such an approach, previously unrecognized biological and therapeutic compl

272 These results uncover a previously unrecognized cell-autonomous, light-sensing m

273 Together these studies reveal the previously unrecognized conformational cycle of ABCG2.

274 Herein we identify a previously unrecognized connection between these two pat

275 dependent degradation, unveiling a novel and previously unrecognized mechanism involved in regulation

276 ation of Arabidopsis CRY1 and CRY2 provide a previously unrecognized mechanism underlying the differe

277 Our results reveal distinctive and previously unrecognized myonuclear subtypes within dystr

278 Our findings demonstrate a previously unrecognized role of host IL-6 response in th

279 ive new colonies, and 21 additional colonies previously unreported and likely missed by previous surv

280 As further shown, the previously unreported dicarboxylic acids are easily turn

281 with 2009-2014.The outbreak was caused by a previously unreported molecular type (ST-13578), initial

282 Our findings unveil the previously unreported post-translational control of LGR

283 Eligible patients had previously untreated acute myeloid leukaemia, an Eastern

284 cohort study of the predictive accuracy of a previously validated polygenic risk score was assessed a

285 ere estimated at 1-kmx1-km grid cells from a previously validated prediction model.

286 We use a previously-validated test of criticality: avalanche dyna

287 Previously, we analyzed protein turnover rates in cultur

288 Previously, we and others showed that P130CAS mediates V

289 Previously, we demonstrated PCSK6 upregulation in human

290 Previously, we demonstrated that integrin alpha5beta1 an

291 Previously, we described a strategy to rapidly identify

292 Previously, we developed an efficient method for the sim

293 Previously, we have demonstrated that the 5-HT(3A)-ICD i

294 Previously, we reported the ability of hexamethyldisilox

295 Previously, we showed that active K-Ras4B dimerizes in s

296 Previously, we showed that ATP-DnaA, not ADP-DnaA, under

297 Previously, we showed that rat kidney mesangial cells di

298 on-subtype-specific regulatory elements that previously went undetected in bulk brain tissue samples.

299 A core collection developed previously with smaller number of clones representing WC

300 Previously, XRN2 was implicated in DNA double strand bre