ライフサイエンスコーパス: primary sensory

1 This ATP excites primary sensory afferent fibers and also stimulates neig

2 ns in the spinal cord and central targets of primary sensory afferents (nucleus of the solitary tract

3 Primary sensory afferents and their neighboring host-def

4 ion of the presynaptic NMDAR activity in the primary sensory afferents is an effective approach to at

5 Primary sensory afferents of the dorsal root ganglion (D

6 ed with enhanced release of Substance P from primary sensory afferents.

7 using conventional seed-based analyses in 3 primary sensory and 3 association networks as normal you

8 rneuron dendrite remodeling is common across primary sensory and higher-level cortices.

9 ccur regularly during REM sleep, but only in primary sensory and motor areas and mostly in layer 4, t

10 Networks derived using primary sensory and motor cortex seeds were already well

11 In contrast, "unimodal" regions such as the primary sensory and motor cortices show a much more sing

12 In contrast, primary sensory and motor cortices showed effector-indep

13 tate, high GSCORR was observed mainly in the primary sensory and motor regions, whereas low GSCORR wa

14 long the cortical processing hierarchy, from primary sensory and motor to frontal cortices.

15 d allow signals to flow reciprocally between primary sensory and parietal cortex.

16 and function correspond closely in unimodal, primary sensory, and motor regions, but diverge in trans

17 We conclude that MT resembles a primary sensory area by developing early, and that the e

18 and posterior cingulate cortex, and several primary sensory areas (all r > 0.58; P < 0.05, corrected

19 cal layout consists of few modality-specific primary sensory areas and a multitude of higher order on

20 subjects for compensation within nondeprived primary sensory areas as a result of blindness early in

21 studied structures, which was greater in the primary sensory areas during the encoding (Wilcoxon rank

22 While studies in other primary sensory areas have elucidated that pyramidal and

23 s generating the topographic organization of primary sensory areas in the neocortex are well studied,

24 STATEMENT Variability of neural responses in primary sensory areas is puzzling, as it is detrimental

25 ICANCE STATEMENT Cortical processing even in primary sensory areas is strongly influenced by nonlocal

26 on of neuronal and non-neuronal cells in the primary sensory areas of the neocortex of a South Americ

27 multisensory integration emerges already in primary sensory areas or is deferred to higher-order ass

28 upport the view that intermingled neurons in primary sensory areas send specific stimulus features to

29 Cortical-feedback projections to primary sensory areas terminate most heavily in layer 1

30 the transcription factor Ctip1 functions in primary sensory areas to repress motor and activate sens

31 to other canids, cortical regions beyond the primary sensory areas will need to be examined in detail

32 ent development should be revisited even for primary sensory areas, in that the connectivity basis fo

33 ral mechanisms of cross-modal integration in primary sensory areas, such as the primary visual cortex

34 imited to a spatial window of integration in primary sensory areas.

35 higher order association areas and to spare primary sensory areas.

36 of topographic maps, which are so helpful in primary sensory areas.

37 y serve a general modulatory function across primary sensory areas.

38 minar circuitry similar to those observed in primary sensory areas.

39 als in the brain of head-fixed mice, even in primary sensory areas.

40 ng is known to induce cortical plasticity in primary sensory areas.

41 om multiple senses, even at the level of the primary sensory areas.

42 ed cortical association areas but extends to primary sensory areas.

43 fat was considered to be tasteless, and its primary sensory attribute was believed to be its texture

44 , we isolated dorsal root ganglia (DRG), the primary sensory cell body for peripheral nerve injury ge

45 a magnetic sense exists, the location of the primary sensory cells and the underlying molecular mecha

46 alibut larvae at the time of hatching may be primary sensory cells or interneurons representing the f

47 Many primary sensory cilia exhibit unique architectures that

48 uid movement over epithelial surfaces, while primary (sensory) cilia play roles in cellular signallin

49 se the possibility that basic dysfunction in primary sensory circuitry may illustrate mechanisms impo

50 Primary sensory circuits encode both weak and intense st

51 The gain of signaling in primary sensory circuits is matched to the stimulus inte

52 m rod and cone photoreceptors, acting as the primary sensory conduit mediating non-image-forming resp

53 tterns of plaques in the vibrissae-receptive primary sensory cortex (barrel cortex), in which the cor

54 the anterior cingulate cortex (ACC) and the primary sensory cortex (S1) in rats with inflammatory pa

55 normalized coordinates, broadcast throughout primary sensory cortex and provides strong modulation of

56 irst to reveal distinct interactions between primary sensory cortex and rIFC in humans and suggest th

57 e unique or overlapping representations in a primary sensory cortex and whether learning can modulate

58 Recent evidence suggests that neurons in primary sensory cortex arrange into competitive groups,

59 al connectivity between thalamus and lateral primary sensory cortex but reduced connectivity between

60 study and past measurements, which show that primary sensory cortex codes the whisking envelope as a

61 orward inhibition.SIGNIFICANCE STATEMENT The primary sensory cortex contains six distinct layers that

62 ort enhanced hippocampal connectivity to the primary sensory cortex during retrieval of extinguished

63 iated with increased activations in the left primary sensory cortex face area due to median nerve sti

64 cortex leg area during handgrip and the left primary sensory cortex face area during median nerve sti

65 dies have demonstrated the importance of the primary sensory cortex for the detection, discrimination

66 -sensory influences on neuronal responses in primary sensory cortex has been observed previously usin

67 Neurons in primary sensory cortex have diverse response properties,

68 clusion, SDs are inducible preferentially in primary sensory cortex in mice and most likely in humans

69 ultiple cubic millimeter regions of vibrissa primary sensory cortex in mouse.

70 robe, to image tissue oxygenation in the rat primary sensory cortex in response to sensory stimulatio

71 ortex are uniquely regulated compared to the primary sensory cortex in ways that render them vulnerab

72 to the more likely stimulus modality and the primary sensory cortex may participate in the redistribu

73 anges in neuronal representation as early as primary sensory cortex mediate the perceptual advantage

74 the periphery may shape the organization of primary sensory cortex of other modalities as well.

75 The subgranular layers (layers 5 and 6) of primary sensory cortex provide corticofugal output to th

76 Layer (L)2 is a major output of primary sensory cortex that exhibits very sparse spiking

77 ive learning reconfigures neural circuits in primary sensory cortex to "learn" associative attributes

78 es to a sensorimotor cortical circuit (i.e., primary sensory cortex to primary motor cortex).

79 l responses, not only in their corresponding primary sensory cortex, but in other primary sensory cor

80 bilateral sensorimotor regions of interest (primary sensory cortex, dorsal and ventral premotor cort

81 sufficient to generate attractor dynamics in primary sensory cortex.

82 nd overlapping thalamic representations than primary sensory cortex.

83 memory is stored via synaptic plasticity in primary sensory cortex.

84 dulation in supragranular pyramidal cells in primary sensory cortex.

85 n of activity across neuronal populations in primary sensory cortex.

86 est new complexities in the relation between primary sensory cortical activity and behavior.SIGNIFICA

87 hroughout thalamic, limbic, and particularly primary sensory cortical areas in addition to known head

88 ome receptive field properties of neurons in primary sensory cortical areas.

89 tical plasticity extends beyond reshaping of primary sensory cortical fields to respecification of th

90 from the well-known patterns identified for primary sensory cortical regions.

91 l linkage of structure and function within a primary, sensory cortical area.

92 tical targets of these layers from the three primary sensory cortices (somatosensory, auditory, and v

93 that an anatomical trade-off exists between primary sensory cortices and anterior prefrontal cortex

94 elated impairment in the interaction between primary sensory cortices and subcortical regions suggest

95 odal interactions are commonplace across the primary sensory cortices and that some of the underlying

96 s with ASDs displayed stronger activation in primary sensory cortices and the amygdala (P < .05, corr

97 gh deficits in sensory function suggest that primary sensory cortices are affected by aging, our unde

98 Whether primary sensory cortices are essentially multisensory or

99 Response properties in primary sensory cortices are highly dependent on behavio

100 ing body of literature has demonstrated that primary sensory cortices are not exclusively unimodal, b

101 Altogether, the data show that primary sensory cortices can encode for cues predicting

102 Grouped primary sensory cortices defined network inputs, display

103 The primary sensory cortices display topographic organizatio

104 nterneurons is involved in map remodeling of primary sensory cortices during critical periods of deve

105 arietal cortices, and less activation in the primary sensory cortices during rest and sensory stimula

106 In contrast, primary sensory cortices have few NFTs, even in late-sta

107 oscillations and direct connectivity between primary sensory cortices in visual-somatosensory interac

108 ular cortex (GC) as a model for studying how primary sensory cortices integrate sensory, affective, a

109 tunes cortical processing, but unlike other primary sensory cortices it does not modify the retinoto

110 he feature-selective spatial organization of primary sensory cortices remains controversial.

111 nt studies show sustained neural activity in primary sensory cortices that can represent the timing o

112 e functional connectome and transitions from primary sensory cortices to higher-order brain systems.

113 g hierarchy; claustrum neurons projecting to primary sensory cortices were scant and restricted in di

114 high levels of catecholamines strengthen the primary sensory cortices, amygdala and striatum, rapidly

115 We found that, for all three primary sensory cortices, double-labeled cells were extr

116 ed almost exclusively through studies of the primary sensory cortices, for which principles of lamina

117 Sensory areas, especially primary sensory cortices, have long been held to be invo

118 e topographical representation seen in other primary sensory cortices, making it difficult to test th

119 In primary sensory cortices, thalamocortical (TC) inputs ca

120 In primary sensory cortices, there are two main sources of

121 network connectivity profiles downstream of primary sensory cortices, to investigate neural reorgani

122 These results indicate that primary sensory cortices, traditionally regarded as unis

123 the degree of clustering of plaques between primary sensory cortices, we found that the degree of pl

124 the cerebral cortex is well described in the primary sensory cortices.

125 roanatomical precursors are predominantly in primary sensory cortices.

126 ponding primary sensory cortex, but in other primary sensory cortices.

127 mic systems that project to middle layers of primary sensory cortices.

128 o changes were found for connectivity within primary sensory cortices.

129 rhemispheric functional connectivity between primary sensory cortices.

130 epresentations have been observed throughout primary sensory, decision-making, and motor brain areas.

131 A primary sensory difference was observed among wine sampl

132 eity in threshold sensitivity among the 5-30 primary sensory fibers innervating a single inner hair c

133 early sensory regions, in addition to their primary sensory functions, may be actively involved in p

134 Hence, we systematically studied primary sensory ganglia in rat to determine if the perip

135 V1 is primarily restricted to nociceptors in primary sensory ganglia, with minimal expression in a fe

136 from around postnatal day 7 (P7), before the primary sensory inner hair cells (IHCs), which become co

137 cortex and some parts of the amygdala: 1) a primary sensory input population (intercalated pallium);

138 luences olfactory processing as early as the primary sensory input to the brain by modulating norepin

139 pioid-induced inhibition and potentiation of primary sensory input were abrogated in Oprm1-cKO mice.

140 dLGN; however, their direct influence on the primary sensory input, namely retinogeniculate afferents

141 Primary sensory maps typically arise by molecular cues,

142 direction of the Earth's magnetic field, the primary sensory mechanism behind this remarkable feat is

143 orting essential functions such as language, primary sensory modalities, and motor function.

144 in part to human dependence on vision as our primary sensory modality, research on olfactory communic

145 tion cortex resulted in less laterality than primary sensory/motor cortices.

146 is anchored by, at one end, regions serving primary sensory/motor functions and at the other end, tr

147 l surface-and are precisely equidistant-from primary sensory/motor morphological landmarks.

148 an alter functional properties of neurons in primary sensory neocortex but it is poorly understood ho

149 t selective synchronization between rIFC and primary sensory neocortex occurs in these frequency band

150 7-14 Hz) and beta (15-29 Hz) oscillations in primary sensory neocortical areas are enhanced in the re

151 tch sensation results from the excitation of primary sensory nerve endings in the skin, but the under

152 stained electrical activation of nociceptive primary sensory nerve fibres.

153 process of sensory transduction in cutaneous primary sensory nerve terminals, which converts thermal

154 buted to release of mediators that sensitize primary sensory nerves.

155 ed increased functional connectivity between primary sensory networks and subcortical networks (thala

156 connectivity using seeds from two comparison primary sensory networks: visual and auditory networks.

157 In vitro primary sensory neuron culture systems were subjected to

158 ing molecules responsible for this change in primary sensory neuron excitability are still not well d

159 athways are segregated immediately after the primary sensory neuron in the chemotaxis circuit, and se

160 Combining primary sensory neuron-specific GCaMP3 imaging with a tr

161 despite both forms occurring within the AWC primary sensory neuron.

162 nctional interactions in a sub-population of primary sensory neurons (PSN).

163 They are expressed by primary sensory neurons and by glial cells in the centra

164 nish the resting membrane potential of mouse primary sensory neurons and cause cold-resistant hyperex

165 The lipid sensitizes TRPV1 ion channels in primary sensory neurons and causes increased frequency o

166 tion channel V1 (TRPV1) is also expressed in primary sensory neurons and detects painful stimuli such

167 unsaturated bonds, activate TRPA1 to excite primary sensory neurons and enteroendocrine cells.

168 ts high voltage-activated Ca(2+) channels in primary sensory neurons and excitatory synaptic transmis

169 alysis, metabolomics, and calcium imaging of primary sensory neurons and find no evidence of ligands

170 Cbln2 expression tends to be more common in primary sensory neurons and in second-order sensory regi

171 avbeta(3) subunit augments HVACC activity in primary sensory neurons and nociceptive input to dorsal

172 c proteins that are exclusively expressed in primary sensory neurons and provoke pain in humans.

173 tor) that decreases glucose-induced death of primary sensory neurons and reverses numerous clinical i

174 t the molecules that mediate chronic itch in primary sensory neurons and skin.

175 suggest that DOR-KOR heteromers exist in rat primary sensory neurons and that KOR antagonists can act

176 xtensive localization of the EP3 receptor in primary sensory neurons and the spinal cord.

177 or leading to its functional inactivation in primary sensory neurons and to an efficacious attenuatio

178 e receptor 7 (TLR7) was expressed in C-fiber primary sensory neurons and was important for inducing i

179 isms mediating histamine-independent itch in primary sensory neurons are largely unknown.

180 Many primary sensory neurons are polymodal, responding to mul

181 2I showed selective in vitro C2I delivery to primary sensory neurons but not motor neurons.

182 SDHN following the activation of nociceptive primary sensory neurons by burn injury, capsaicin applic

183 in HEK293 cells, Xenopus laevis oocytes, and primary sensory neurons by measuring Ca(2+) signals.

184 Using these methods, primary sensory neurons can be transfected with an effic

185 otection against glucose-induced toxicity of primary sensory neurons compared to 2.

186 How primary sensory neurons contribute to persistent pain re

187 Primary sensory neurons convey information from the exte

188 The peripheral terminals of primary sensory neurons detect histamine and non-histami

189 MOR ablation in primary sensory neurons diminishes analgesic effects pro

190 Primary sensory neurons form the interface between world

191 plitude of CXCL12-induced Ca(2+) response in primary sensory neurons from CCD mice was significantly

192 rent in prephenotype dorsal root ganglia and primary sensory neurons from dt mice, suggesting they ar

193 Adult Wistar rat primary sensory neurons grown at physiological pH 7.4, t

194 However, the function of ERK2 in primary sensory neurons has not been directly tested.

195 Viral tracing of the circuits engaged by primary sensory neurons has, however, been hampered by t

196 In cultured primary sensory neurons IL-31 triggered Ca(2+) release a

197 at induction of eIF2alpha phosphorylation in primary sensory neurons in a chronic inflammation pain m

198 TLR3 is expressed mainly by small-sized primary sensory neurons in dorsal root ganglions (DRGs)

199 lly to transcriptional repression of MORs in primary sensory neurons in neuropathic pain.

200 nstrate a critical role of MORs expressed in primary sensory neurons in opioid analgesia and suggest

201 roid hormones, targeted TRPA1 in peptidergic primary sensory neurons in rodent and human cells expres

202 mined the specific role of MORs expressed in primary sensory neurons in the analgesic and hyperalgesi

203 Primary sensory neurons in the DRG play an essential rol

204 al mechanical origin of tactile information, primary sensory neurons in the trigeminal ganglion (Vg)

205 the response magnitude of whisker-sensitive primary sensory neurons in the trigeminal ganglion.

206 Presynaptic inhibition (PSI) of primary sensory neurons is implicated in controlling gai

207 essional changes of pain-associated genes in primary sensory neurons of DRG are critical for neuropat

208 dominant background potassium current in the primary sensory neurons of the dorsal root and trigemina

209 ature olfactory sensory neurons (mOSNs), the primary sensory neurons of the olfactory epithelium.

210 expressed on olfactory sensory neurons, the primary sensory neurons of the olfactory epithelium.

211 terminals of olfactory sensory neurons (the primary sensory neurons of the olfactory system, which p

212 l molecular detector of cold temperatures in primary sensory neurons of the somatosensory system.

213 s of these results under the assumption that primary sensory neurons of the trigeminal ganglion are s

214 Eliminating NMDARs in primary sensory neurons or alpha2delta-1 KO also attenua

215 Our findings suggest that MyD88 in primary sensory neurons plays an active role in regulati

216 in controlling the intrinsic excitability of primary sensory neurons possibly via Ca(2+)-activated SK

217 Thus, the primary sensory neurons responsive to beta-alanine are l

218 Activation of most primary sensory neurons results in transduction currents

219 A recent study in primary sensory neurons shows that electrical activity--

220 ficantly blunted phosphorylation of c-Jun in primary sensory neurons subjected to trophic deprivation

221 causative factor may be that only 50-60% of primary sensory neurons succeed in regenerating axons af

222 Thus, PKD1, PKD2, and PKD3 are expressed in primary sensory neurons that mediate neurogenic inflamma

223 dorants by olfactory sensory neurons (OSNs), primary sensory neurons that physically contact odor mol

224 t acts as a coincidence detector that allows primary sensory neurons to integrate information from ne

225 The principle by which unmyelinated primary sensory neurons transducing thermal, itch and pa

226 ransient receptor potential melastatin 8) in primary sensory neurons using both pharmacological inhib

227 ive ligand-gated channel highly expressed in primary sensory neurons where it mediates nociception.

228 s defined by the existence of a diversity of primary sensory neurons with unique biological features

229 Bone cancer upregulated CCR2 in primary sensory neurons, and CCR2 antagonism effectively

230 olfactory abilities likely originates in the primary sensory neurons, and suggest that hormonal modul

231 and LPC 16:0 can induce Ca(2+) transients in primary sensory neurons, and we identify LPC 18:1 as a p

232 In cultured rodent primary sensory neurons, BoNT-A decreased the proportion

233 , wheat germ agglutinin (WGA), is induced in primary sensory neurons, but only after transection of t

234 t ganglia (DRG), which contain the somata of primary sensory neurons, have increasingly been consider

235 MORs in primary sensory neurons, particularly those expressed pr

236 sfer is a feature shared by other classes of primary sensory neurons, permitting the identification a

237 f WNT/frizzled/beta-catenin signaling in the primary sensory neurons, the spinal dorsal horn neurons,

238 espite prominent expression of NMDARs in DRG primary sensory neurons, the unique role of peripheral N

239 in sodium channel subunit Nav1.8-expressing primary sensory neurons, to examine the unique role of n

240 vents might also impact central processes of primary sensory neurons, triggering in nociceptors a hyp

241 In trigeminal primary sensory neurons, we detected single-channel acti

242 C(50) = 0.1 nm) and TRPA1 (IC(50) = 2 nm) in primary sensory neurons, whereas RvE1 and RvD1 selective

243 nnections between cochlear sensory cells and primary sensory neurons, without loss of the sensory cel

244 between neurotropic herpesviruses and murine primary sensory neurons.

245 el Nav1.8 is expressed almost exclusively in primary sensory neurons.

246 Kv7.2 activity increases the excitability of primary sensory neurons.

247 nduction and maintenance of sensitization of primary sensory neurons.

248 led receptor expressed by a subpopulation of primary sensory neurons.

249 pression and function of Cavbeta subunits in primary sensory neurons.

250 nd murine TRPM8 channels, including those on primary sensory neurons.

251 d its ligand ephrinB2 in the dorsal horn and primary sensory neurons.

252 voltage-gated calcium and sodium currents in primary sensory neurons.

253 ally expressed in small-diameter nociceptive primary sensory neurons.

254 s a major determinant of the excitability of primary sensory neurons.

255 itochondrial functions in cultured adult rat primary sensory neurons.

256 observed at the spinal level also applies to primary sensory neurons.

257 of G-protein coupled receptors expressed in primary sensory neurons.

258 irect synaptic input from both pain and itch primary sensory neurons.

259 erve injury on the regenerative state of the primary sensory neurons.

260 ervous system, including the spinal cord and primary sensory neurons.

261 s activates the D1-like dopamine receptor on primary sensory neurons.

262 riety of receptors and channels expressed by primary sensory neurons.

263 f TRPM8 channels in these injured trigeminal primary sensory neurons.SIGNIFICANCE STATEMENT We unveil

264 r 1 TGR5 (encoded by GPBAR1) is expressed by primary sensory neurons; its activation induces neuronal

265 It is also the brain's primary sensory nucleus for visceral sensations relevant

266 Cilia of olfactory sensory neurons are the primary sensory organelles for olfaction.

267 ostsynaptic responsiveness highlight how the primary sensory organs have been optimized and can be mo

268 The acoustic radiation (AR) represents a primary sensory pathway that has been largely omitted in

269 izations of AstA- and TK-positive neurons in primary sensory processing centers and higher order inte

270 al representations, even into task-unrelated primary sensory processing regions.

271 e N100 or P200 components, indicating intact primary sensory processing.

272 ly undoing the specific mapping of an entire primary sensory projection.

273 The primary sensory receptive field maps of the olfactory sy

274 Similar to the primary sensory receptor, the inner hair cells (IHCs), t

275 The inner hair cells (IHCs) are the primary sensory receptors adapted for rapid auditory sig

276 Inner hair cells (IHCs) are the primary sensory receptors of the mammalian cochlea, tran

277 association areas, but was also seen in the primary sensory region investigated.

278 ese supramodal patterns included activity in primary sensory regions not directly relevant to the tas

279 and that remodeling rates are similar across primary sensory regions of different modalities, but may

280 It is generally held that non-primary sensory regions of the brain have a strong impac

281 ined significantly more non-neurons than the primary sensory regions.

282 orms not only the information content of the primary sensory representation, but also its underlying

283 and suggest that synchrony between rIFC and primary sensory representations plays a role in the inhi

284 This linkage of amygdalar and LC output to primary sensory signaling may have implications for affe

285 These results suggest that primary sensory structures develop through the concurren

286 surfaces of the frontal lobe, extending into primary sensory, superior parietal, and anterior superio

287 d by inner hair cells (IHCs), which form the primary sensory synapse.

288 ity of prey species that use vision as their primary sensory system and suppressed the activity of sp

289 The primary sensory system requires the integrated function

290 ike other predators that use vision as their primary sensory system, bats compute the three-dimension

291 via their long-range feedback projections to primary sensory thalamic nuclei.

292 Here we report that neurons in the primary sensory thalamus of the mouse vibrissal system (

293 ew example of cross-modal integration in the primary sensory thalamus.

294 rostructural differentiation traversing from primary sensory to limbic regions that followed shifts i

295 t to anterograde transsynaptic transfer from primary sensory to spinal target neurons, and can deline

296 AWC-sensed odors by acting downstream of the primary sensory transduction.

297 Recordings from primary sensory trigeminal ganglion neurons show that th

298 lasting transduction of the vast majority of primary sensory vagal neurons without transduction of pa

299 chanical signals so generated constitute the primary sensory variables upon which these animals base

300 alities, but may differ in magnitude between primary sensory versus higher cortical areas.