ライフサイエンスコーパス: primary structure

1 be alternatively stabilized by altering the primary structure.

2 capping enzyme that recognizes the same CTD primary structure.

3 ated by signal sequences that vary widely in primary structure.

4 hat are genetically encoded in the protein's primary structure.

5 predicts previously unrecognized features of primary structure.

6 alpha-defensins are dependent on the peptide primary structure.

7 hat either reseal broken RNAs or alter their primary structure.

8 ins a C (291)XXC (294)XXC (297) motif in its primary structure.

9 , much effort has been made to determine its primary structure.

10 capsulated within a third zinc finger in the primary structure.

11 ated by trafficking signals encoded in their primary structure.

12 e ER by signal sequences that vary widely in primary structure.

13 ntirely different positional cues in the CTD primary structure.

14 ues residing on two conserved regions of the primary structure.

15 localize exposed and accessible elements of primary structure.

16 nsional structures with sites in the protein primary structure.

17 ir position within the CSC rather than their primary structure.

18 hat either reseal broken RNAs or alter their primary structure.

19 s located remotely to each other in terms of primary structure.

20 h TERT is dictated more by secondary than by primary structure.

21 ccluded by quadromers (four residues) in the primary structure.

22 conformation and function are determined by primary structure.

23 f shell proteins in terms of composition and primary structure.

24 ccinylation sites in proteins based on their primary structure.

25 nteract through a mode of binding other than primary structure.

26 ation environment and without changes in PrP primary structure.

27 rences, suggesting some differences in their primary structure.

28 "unique" ions that unambiguously define the primary structure.

29 ffecting guaiacyl:syringyl ratios and lignin primary structure.

30 e contains 10 selenocysteine residues in its primary structure.

31 pite the absence of a CXXCXXC motif in their primary structures.

32 ed noncellulosic polysaccharide linkages and primary structures.

33 the characterization of peptide and protein primary structures.

34 ased on dendrons and dipeptides with various primary structures.

35 ysis has successfully determined their exact primary structures.

36 in the SwissProt/TrEMBL database of protein primary structures.

37 rotein kinases are highly conserved in their primary structures.

38 nt of cross-species prion transmission while primary structure affects transmission specificity by al

39 Together with ADAMTS12, whose primary structure also predicts a mucin domain, ADAMTS7B

40 rms, which are protein products with various primary structure alterations resulting from gene mutati

41 aracterizes complex proteoforms with unknown primary structure alterations, such as amino acid mutati

42 early indicate that this perturbation in the primary structure alters a structural water interaction

43 ctional significance and conservation of GTF primary structure among enzyme isoforms.

44 Cross-reactivities predicted by primary structure analyses of different isoforms and PR1

45 Primary structure analysis of BjPutA shows it lacks the

46 While primary structure analysis reveals similarities to the c

47 dustry beyond the presently assigned task of primary structure analysis.

48 ction relationships for PutA is derived from primary structure analysis.

49 efensin peptides are highly variable in both primary structure and activity.

50 Up to now, only its primary structure and carbohydrate binding data have bee

51 APCE is similar in primary structure and catalytic properties to membrane-b

52 at several different levels (including both primary structure and conformation).

53 ons defines an unprecedented diversity of MT primary structure and domain organization in the America

54 Here, we studied T cell receptor (TCR) primary structure and function of 605 HLA-A*0201/NY-ESO-

55 tudies intimated that mutations altering the primary structure and function of keratin filaments unde

56 Although the relationship between the primary structure and function of the vertebrate connexi

57 rally encoded reverse transcriptase, but the primary structure and multimeric state of the polymerase

58 prion conversion was driven by a homologous primary structure and occurred independently of a homolo

59 The primary structure and phosphorylation pattern of the tan

60 The primary structure and phosphorylation pattern of the tan

61 ass analysis and characterized the protein's primary structure and post-translational modifications t

62 This review will focus on the primary structure and potential functions of the cytopla

63 esults reveal fundamental differences in the primary structure and signaling potential of the alpha b

64 ating activated FVIII (FVIIIa) with the same primary structure and specific activity as native FVIIIa

65 opt in solution are a function of both their primary structure and surrounding aqueous environment.

66 pes of proteinopathies despite the identical primary structure and that exposure to exogenous pathoge

67 echanisms of energy flow for optimization of primary structure and to appreciate the roles of archite

68 We now report the primary structures and biochemical properties of a famil

69 product, they have significantly dissimilar primary structures and expression levels in different ti

70 y result from stereochemical arrangements in primary structures and folding.

71 tic tool, allowing effective photocontrol of primary structures and functions of proteins.

72 od to determine the similarity between their primary structures and quantify the amount of protein in

73 Both molecules are closely related in their primary structures and share a nearly identical spatiote

74 iating S22W peptides and used to compare the primary structures and to assign the secondary structure

75 nes were analyzed for sorting signals within primary structures and upstream open reading frames that

76 a truncate lacking the N-terminus with known primary structure, and we have established conditions fo

77 virus-like with respect to their small size, primary structures, and bipartite domain organization.

78 ) self-assembling dendrons, based on various primary structures, and combinations of (AB)(y)-AB(3) an

79 cies requires compatible prion protein (PrP) primary structures, and even one heterologous residue at

80 ation, the interactions between amino acids, primary structures, and quaternary conformations of effe

81 Preservation of native "primary" structure, and use of processing to create "sec

82 In several cases, the primary structure appeared biased toward a partially dis

83 Poorly conserved regions of primary structure are peripheral to an essentially ident

84 While deer and elk PrP primary structures are equivalent except at residue 226,

85 Hu-recA1PI had the same primary structure as plasma-derived A1PI (pd-A1PI) excep

86 E, which are highly similar to each other in primary structure as well as to LMPTPs from gram-negativ

87 oss this group of compounds, which differ in primary structure at only three positions: 12, 23, and 2

88 alysis, and information storage, wherein the primary structure begets complex chemical processes.

89 ema tomentosa (TremaHb) are 93% identical in primary structure but differ in oxygen binding constants

90 the system no longer depends simply on its "primary" structure but also on higher-level effects whic

91 l plasticity combined with remodeling of CTD primary structure by kinases and phosphatases provides a

92 Replacement of the wild-type loop 1 primary structure by shorter sequences with a high prope

93 environment in the absence of changes in PrP primary structure can be a source of strain mutations.

94 kine with an atypical, yet highly conserved, primary structure characterized by a short N terminus an

95 Consistent with this unique primary structure, chick GAIP has physiological properti

96 Primary structure comparison of GPCRs has shown that the

97 However, there is extensive primary structure conservation between members of the RN

98 esence of hyperbaric oxygen, and because its primary structure contained a CXXCXXC motif, which is co

99 Distinct primary structures defined by homologous domains shed li

100 r the discovery and prediction of programmed primary structures derived from quasi-equivalent constit

101 The major primary structure differences between the channels inclu

102 g variations among the much larger number of primary structure diversifications introduced during evo

103 These controls include the determination of primary structure effects on intrinsic rate constants fo

104 Despite 52% identity in primary structures, enzymatic properties of human E-NTPD

105 l for HCMV sharing important similarities in primary structure, epidemiology, and pathogenesis.

106 assified into eight different types based on primary structure features.

107 tes grow laterally to form nanosheets as the primary structure, followed by their folding and attachm

108 Plasma Membrane is the primary structure for adjusting to ever changing conditi

109 ventral region of the inner ear, acts as the primary structure for the perception of sound.

110 The primary structure for these peptides was determined usin

111 irst, short-range disulfides relative to the primary structure formed, both native and nonnative.

112 opsin, BPR) differing by 20-30% in predicted primary structure from the first-discovered green-absorb

113 adult cardiac myocytes was used to identify primary structure/function effects of mutant cTnI.

114 The complete determination of GAG primary structures has been hampered by the lack of sens

115 ely defined molar mass and monomer sequence (primary structure) have many potential high-value applic

116 min ions is largely unaffected by changes in primary structure; however, the stabilities of intermedi

117 , and the smallest alteration to polypeptide primary structure (i.e. point mutation) can result in th

118 x mimics a helix that is integrated into the primary structure in distantly related LC7 homologs.

119 Fcp1 and to illuminate the importance of CTD primary structure in Ser2 and Ser5 phosphatase activity.

120 The antennal lobe (AL) is the primary structure in the Drosophila brain that relays od

121 nformatics to infer secondary structure from primary structure in these proteins.

122 ly small two amino acid length difference in primary structure, in vitro studies demonstrate that Abe

123 transfer reactions, can be adapted to obtain primary structure information from entire protein ions,

124 structured, suggesting that proximity in the primary structure is a major factor in promoting helix f

125 The primary structure is clockwise/counterclockwise chiral c

126 redox reaction rate for VO(x) in the Keggin primary structure is comparable to that of bulk V(2)O(5)

127 l evidence to support the theory that lignin primary structure is controlled at the proteinaceous lev

128 Its domain organization and primary structure is similar to a novel long form of ADA

129 The primary structure is threaded through the unassigned foc

130 facilitates deep interrogation of proteoform primary structure, is highly tunable, allows for adjustm

131 l II strongly conserves a dnaE-like, Pol III primary structure, it is proposed that it be renamed DNA

132 Although Y is not related to S105 in its primary structure, its characterization might prove usef

133 on is evolutionarily more conserved than the primary structure itself.

134 ithin regions of the alpha- or gamma-subunit primary structure known to contribute to the agonist bin

135 multiple cleavage sites within the CCTalpha primary structure, leading to the generation of a 26-kDa

136 Although divergent at the primary structure level, CAL1 thus binds CENP-A/H4 using

137 The V(H) region primary structure may affect complement activation, whic

138 describe how intrinsic features of antibody primary structure, most notably the interspersed segment

139 Subsequent fragmentation of the repeating primary-structure motif yielded a 42-residue polypeptide

140 nt as a chaperone, while conservation of the primary structure--necessary for ubiquitin's function as

141 nitride membrane, can be used to detect the primary structure of a denatured protein molecule.

142 Here, we describe the complete primary structure of a monomeric non-specific lipid tran

143 -amino acid peptide (RQH(C7)), which has the primary structure of a motif in the large intracellular

144 report the complete characterization of the primary structure of a multimeric glycoprotein in a sing

145 The primary structure of a protein consists of a sequence of

146 laced at different specific locations in the primary structure of a small protein, barstar, have been

147 We have determined the primary structure of acetylcholinesterase from Schistoso

148 ng variation among species in the number and primary structure of alpha-defensin paralogs.

149 OOH) or Orn (-CH(2)CH(2)CH(2)NH(2)) into the primary structure of an 11 amino acid peptide enables se

150 d function from metal-site signatures in the primary structure of ArsR family proteins are discussed.

151 n this study, we have substituted the entire primary structure of AT with alanine or cysteine to iden

152 The primary structure of BMK1 is distinct from other MAPK me

153 The unusual primary structure of C-hordein has highly repetitive seq

154 The primary structure of canonical amyloid-beta-protein was

155 several classes of enzymes that modulate the primary structure of chromatin to regulate various DNA-d

156 We report here the primary structure of Ctnnb1 using PCR-based methods and

157 The primary structure of cvRtp1 is more similar to that of t

158 oinformatic and phylogenetic analyses of the primary structure of defensin-2 support its role as an a

159 The primary structure of dematin consists of a C-terminal do

160 Primary structure of dematin includes a loosely folded c

161 dies found that despite the highly divergent primary structure of different amyloid-forming proteins,

162 the relationship between the dynamics of the primary structure of DNA and mutagenesis associated with

163 ted by specific small peptides mimicking the primary structure of each acylation site except that the

164 The primary structure of each has been deduced from the cDNA

165 The primary structure of Foxp3 contains four cyclin-dependen

166 The primary structure of Gem and other RGK family members (R

167 mass spectrometry method to characterize the primary structure of histidine-tagged alpha-synuclein is

168 ormation on only half of the peptides in the primary structure of HSA.

169 amino acid composition of proteins, and the primary structure of introns and noncoding DNA.

170 Examining the primary structure of IRAK, we identified three putative

171 and BcForms, a toolkit for representing the primary structure of macromolecules as combinations of r

172 The primary structure of mammalian protamine I can be divide

173 which was predicted from an alignment of the primary structure of miropin with those of well studied

174 The complete primary structure of MM-kappaI was determined by Edman s

175 The approach makes the primary structure of most proteins accessible to the too

176 ation of human Ack (chromosome 3q29) and the primary structure of murine Ack.

177 Here we present the primary structure of MYP as predicted from cDNAs of two

178 olding and allowed definition of the minimum primary structure of N- and C-terminal active site pepti

179 Complete coverage of the primary structure of native ZP3, 96% of ZP2, and 56% of

180 posed codes: the genetic code to specify the primary structure of proteins and the splicing code to e

181 sensitivity, allows characterization of the primary structure of proteins in a robust and faster man

182 ngation kinetics are causally encoded in the primary structure of proteins, and signatures of evoluti

183 of tandem mass spectrometry to determine the primary structure of proteolytic peptides can be exploit

184 stablishing that binding is dependent on the primary structure of PrP.

185 ration, two phenomena also influenced by the primary structure of PrP.

186 The primary structure of RLF, as reported in the literature,

187 remains poorly understood compared with the primary structure of single nucleosomes or the tertiary

188 Here, we present the primary structure of Sp-SPCA, which is 912 amino acids a

189 Although controlling the primary structure of synthetic polymers is itself a grea

190 Experimental evidence indicates that the primary structure of the beta2-alpha2 loop region (resid

191 The primary structure of the binding segment, termed MAGUK b

192 embrane domains of the protein to target the primary structure of the Cdr1p.

193 ese residues are far from D1-Asp(170) in the primary structure of the D1-polypeptide, imply that the

194 strated biomimetic self-assembly wherein the primary structure of the dendron and to a lesser extent

195 large hollow spheres that is dictated by the primary structure of the dendron.

196 The primary structure of the enzyme, which we now call P3H1,

197 nitial report on the characterization of the primary structure of the extrapallial (EP) protein by RT

198 limited examples of marked constraint in the primary structure of the H and L chain V regions exist,

199 atory functions, we investigated whether the primary structure of the H1-H2 domain in alpha-1 (alpha1

200 L-S-K(273), both of which are present in the primary structure of the human type 1 3beta-HSD/isomeras

201 ic acid formation and decarboxylation on the primary structure of the mAb through characteristic mass

202 ow the presentation of a model of the entire primary structure of the mycobacterial mycolyl arabinoga

203 g specificity is primarily determined by the primary structure of the peptide, which explains the spe

204 The primary structure of the prion protein (PrP) is believed

205 The primary structure of the protein precursor was identifie

206 cificity is determined by differences in the primary structure of the protein rather than species-spe

207 equires only experimental peak lists and the primary structure of the protein, from which the peaks e

208 This result corroborates with the primary structure of the protein, which contains sequenc

209 orm decodes the information contained in the primary structure of the proteins, allowing the identifi

210 The primary structure of the recombinant enzyme is identical

211 The fusion event splits the primary structure of the Rossmann fold into two halves.

212 hat the Arf-activating property, but not the primary structure of the Sec7 domain, is indispensable f

213 The primary structure of the splicing region, the reproducib

214 on products can be heavily influenced by the primary structure of the surrounding peptide.

215 ted by PCR amplification, and determined the primary structure of the Vbeta-Dbeta-Jbeta junctional re

216 1 fimbriae cannot be ascribed solely to the primary structure of their respective FimH subunits, but

217 s, a perspective that neglects the polymeric primary structure of these biological macromolecules, th

218 Although the primary structure of these components is fairly well dec

219 The unusual primary structure of this component was confirmed by mas

220 The primary structure of this ligase shows a unique N-termin

221 The primary structure of this motif is similar to polybasic

222 The primary structure of this small (9.9 kDa) monomeric prot

223 The results of this analysis showed that the primary structure of this strong antigenic region is hig

224 Mapping of the derivatized peptides onto the primary structure of transferrin indicated that the oxid

225 of the Asn(81)-Asn(149) fragment within the primary structure of yeast cyclophilin CPR1 by replacing

226 The primary structure of Z is devoid of hydrophobic transmem

227 The predicted primary structure of Zfp488 is evolutionarily conserved

228 The primary structures of AtIpk2alpha and AtIpk2beta are 70%

229 fferences exist between LANA1 and EBNA1, the primary structures of both proteins have evolved to mini

230 gnment was used as a template to compare the primary structures of caspases 2, 4-6, and 9-11 to build

231 ades, researchers have tried to identify the primary structures of circulating carboxyl-terminal para

232 The primary structures of COX-1 and COX-2 are very similar e

233 Inspection of the primary structures of CzrA and NmtR, coupled with previo

234 The primary structures of deer and elk prion proteins differ

235 Despite a high similarity between the primary structures of E3BP and E2, the E3-binding domain

236 deed be attributed to differences in the PrP primary structures of either donor and acceptor species

237 The conservation of primary structures of gamma-subunits across mammalian sp

238 The primary structures of mouse ZP1, ZP2, and ZP3 have been

239 netic encoding of assembly instructions into primary structures of panels, strands, and nets will lea

240 The primary structures of peptides may be adapted for effici

241 The primary structures of proteins may also reflect natural

242 xhibited extensive diversity relative to the primary structures of rhesus myeloid alpha-defensins.

243 The primary structures of Sp-PMCA and Sp-SERCA in the sea ur

244 We confirm the primary structures of the agrD encoded cyclic AIPs of St

245 erent protective groups of the dipeptide and primary structures of the dendron.

246 rspecies prion transmission decreases as the primary structures of the infectious proteins diverge.

247 Comparisons of the primary structures of the Na,K-ATPase alpha-isoforms rev

248 possibly reflecting loose constraints on the primary structures of the proteins involved.

249 The primary structures of the purified proteins were verifie

250 now be developed solely on the basis of the primary structures of the target proteins.

251 The primary structures of these related kinases contain 501

252 Notably, the deduced primary structures of these two highly homologous polype

253 on a complex interplay of different factors (primary structures of TM domains and juxtamembrane regio

254 possibly others, very subtle changes in the primary structure or in the solution conditions can dram

255 Cs to aggregate in vivo, such as the protein primary structure or local environment, are intensive ar

256 hether species-specific distinctions in ISA1 primary structure, or metabolic differences in tissues,

257 hosphatases, there is little conservation of primary structure outside of the cysteine-containing P-l

258 Sturgeon MGP shows a primary structure, post-translation modifications, and p

259 demonstrated the extensive heterogeneity in primary structure, post-translational modifications, and

260 er, Glycine 179, a conserved residue in cb5r primary structures, precedes this six-residue "180GxGxxP

261 lecular function of clarin-1 is unknown, its primary structure predicts four transmembrane domains si

262 bility, defined as the percentage of similar primary structures resulting in at least one conserved s

263 ogy on peptides that may have highly diverse primary structures, resulting in differential outcomes a

264 with cortisol resemble each other, but their primary structures share only approximately 40% identity

265 The DLY and ELY primary structures show that they maintain the signature

266 ross-linked by two disulfide bridges, with a primary structure similar to other sea anemone peptides

267 IB than bacterial TopIB, despite its greater primary structure similarity to the bacterial TopIB grou

268 This is based on its primary structure, subcellular localization, and regulat

269 ation of position 67, thereby increasing the primary structure symmetry relationship within the core.

270 The results support the hypothesis that primary structure symmetry within a symmetric protein su

271 In previous studies designed to increase the primary structure symmetry within the hydrophobic core o

272 in a beta-trefoil protein with exact 3-fold primary-structure symmetry that exhibited excellent fold

273 d hemoglobin" family that is much shorter in primary structure than vertebrate and plant hemoglobins.

274 mited proteolysis further defines regions of primary structure that are exposed to aqueous solution.

275 no acid sequence, but which is composed of a primary structure that makes it competent to self-assemb

276 polymers, which present precise monodisperse primary structures that are produced both consistently a

277 that there can be evolutionary selection for primary structures that confer specific membrane-binding

278 ontain the canonical CxxxCxxC motif in their primary structures that is typical of the radical S-aden

279 ne the native fold of a polypeptide from its primary structure, the diversity of pathways that connec

280 However, despite the plasticity of the loop primary structure, the relative spatial positioning of t

281 cate that there are only a few native lignin primary structures, the entire sequences of which now ne

282 s requires detailed knowledge of chromatin's primary structure-the assembly of nucleosomes throughout

283 imilar in localization and tertiary (but not primary) structure to FimH, the type 1 fimbrial adhesin

284 residues, 564 and 690 of the 1024 amino acid primary structure, to form hemolysin (HlyA).

285 es, Lys564 and Lys690 of the 1024-amino acid primary structure, to form hemolysin (HlyA).

286 It has primary structure: Val-Val-Asn-Thr-Pro-Gly-His-Ala-Val-S

287 typically emerge from homochiral programmed primary structures via first principles involving second

288 Opsin's primary structure was analyzed by mass-spectrometric map

289 odifications of the proteins, although their primary structure was identical by MS/MS analysis.

290 A periodic table database of programmed primary structures was elaborated and used to facilitate

291 general features of tertiary structures from primary structures was elaborated.

292 ens are approximately 90% identical in their primary structure, we found that human anionic trypsinog

293 Large differences in the primary structure were observed in serum albumin, apolip

294 short evolutionary conserved regions of its primary structure were scrambled and the mutations were

295 cause of the difficulty in elucidating their primary structures, which range in size between 10 and 8

296 to discover six amphiphilic Janus dendrimer primary structures, which self-assemble into uniform oni

297 peptide (designated AspA) displays an AgI/II primary structure, with alanine-rich (A) and proline-ric

298 tulated that a symmetric constraint upon the primary structure within the core could only be achieved

299 y identifying Msp2 variants that differed in primary structure within the immunogenic hypervariable r

300 present evidence that particular regions of primary structure within the two N-terminal PAS domains