ライフサイエンスコーパス: primordium

1 lls (PGCs) in the C. elegans embryonic gonad primordium.

2 some taxa limbs and genitals share a common primordium.

3 xcr7b expression to the trailing zone of the primordium.

4 y distributions of myosin and Bazooka in the primordium.

5 (ZLI) at the rostral border of the thalamic primordium.

6 a linear Sdf1-signaling gradient across the primordium.

7 cted migration of the Posterior Lateral Line primordium.

8 ed for the initial formation of the thalamic primordium.

9 patterned mature structure from an embryonic primordium.

10 line identity are present caudal to the main primordium.

11 ion of thymic epithelial cells in the thymus primordium.

12 ivision and the initiation of a lateral root primordium.

13 lop from archesporial cells in the L2 of the primordium.

14 l crest cells that migrate to the pancreatic primordium.

15 tivation domain in the leading region of the primordium.

16 properties and forces to shape a solid organ primordium.

17 nt membrane dissolution in the primary mouth primordium.

18 nd lower (abaxial) domains in the developing primordium.

19 overall cellularity or volume of each shared primordium.

20 ed into the condensed cartilage of the digit primordium.

21 gination progresses anteriorly away from the primordium.

22 y the migrating posterior lateral line (pLL) primordium.

23 regulators that are expressed in the spleen primordium.

24 wer (abaxial) domains in the developing leaf primordium.

25 (TCF7L2), in the induction of the pituitary primordium.

26 lls are incorporated into the incipient leaf primordium.

27 bryogenesis and become attached to the brain primordium.

28 unbranched fibers in the center of the brain primordium.

29 nhibitors, Kip1 and Ink4c, in the cerebellar primordium.

30 y migrating zebrafish posterior lateral line primordium.

31 nin-based basement membrane around the gonad primordium.

32 ype II lineages DM1-4, form the posterior EB primordium.

33 ) required for kni expression in the L2 vein primordium.

34 oves forward and merges with the anterior EB primordium.

35 sequent migration of PGCs through the midgut primordium.

36 of secreted factors adjacent to the sensory primordium.

37 espite the early expression of Snail in that primordium.

38 1(+) somatic progenitor pools in the gonadal primordium.

39 ed at embryonic day 16 (E16) in the striatal primordium.

40 ls and reduced vasculogenesis of the splenic primordium.

41 trophoblast progenitors within the placenta primordium.

42 ate patterns of cell division in the growing primordium.

43 dorsal and ventral domains of the forebrain primordium.

44 s a central role in positioning of the organ primordium.

45 el provascular strands within the initiating primordium.

46 he size and shape of a zebrafish sense organ primordium.

47 repressing a root-specific gene lateral root primordium 1 (LRP1) via histone deacetylation.

48 tion of the zebrafish posterior lateral line primordium, a cohort of about 200 cells that migrates ov

49 In the developing leaf primordium, a line is drawn across a field of seemingly

50 e-recombinase line that acts in the cortical primordium after its specification is complete, permitti

51 of the adrenal cortex from the adrenogonadal primordium (AGP) have yet to be determined.

52 e migrating and coalescing into the ganglion primordium, all cells were cycling, cell cycle length wa

53 that the somatopleure acting as the amniotic primordium also serves as a source of embryonic cells, w

54 ure for the zebrafish posterior lateral line primordium, an experimentally tractable model of complex

55 Zic2a and Zic2b in patterning the forebrain primordium, an important signaling source during craniof

56 ion leads to dramatic disorganization of the primordium and a loss of proto-NM formation.

57 s associated with subdivision of the incisor primordium and a multiplication of its stem cell-contain

58 ion is driven by periodic lengthening of the primordium and a stable Wnt/beta-catenin activation doma

59 ls (presumptive progenitors) move out of the primordium and are incorporated into NMs; this results i

60 s are broadly distributed throughout the gut primordium and are not derived from a localized and exog

61 tiates neurogenesis in the larval optic lobe primordium and drives the sequential transition of neuro

62 somite-derived cells migrate into the tongue primordium and give rise to muscle cells in the tongue.

63 gnaling is active in the leading zone of the primordium and global Wnt inactivation leads to dramatic

64 epithelial cells emerges in the early tooth primordium and identify these cells as a signaling cente

65 first cortical cell divisions of the nodule primordium and in growing nodules.

66 xb8a is expressed in the leading part of the primordium and is required for the correct speed and ext

67 f Nf2, NPCs of the cortical hem, hippocampal primordium and neocortical primordium overexpand, while

68 ynamic changes in the zebrafish lateral line primordium and observed interactions between myosin IIA

69 igration, such as the zebrafish lateral line primordium and primordial germ cells, Drosophila border

70 the early steps of patterning of the neural primordium and proliferation of neural progenitors.

71 s auxin signaling in the incipient gynoecial primordium and strengthen the concept that cytokinin reg

72 undantly for morphogenesis of the cerebellar primordium and subsequent cerebellar differentiation, bu

73 Development of the nodule primordium and subsequent nodule maturation was signific

74 interwoven meshwork of the fetal myocardial primordium and subsequent persistence of deep trabecular

75 This close association between the mouth primordium and the anterior neural tube in both ascidian

76 ssential for the expansion of the pancreatic primordium and the development of endocrine islets.

77 after the independent formation of the mouth primordium and the neural tube.

78 in severe reductions in the size of the eye primordium and the transformation of the eye field into

79 vn is not expressed in the embryonic wing primordium and thus has to be induced de novo in the nas

80 bules of Drosophila develop from the hindgut primordium and visceral mesoderm.

81 gradient across the entire A/P extent of the primordium, and acts directly at a distance from its sou

82 ccumulate in the shoot apical meristem, leaf primordium, and emerging petiole.

83 mig-38 is expressed in the gonad primordium, and expression continues throughout DTC migr

84 on and skeletogenesis only the ventral brain primordium, and not the prechordal plate, is an importan

85 due to ectopic apoptosis in the dorsal wing primordium, and we could rescue wing development in the

86 ossible mechanisms to polarize the incipient primordium are discussed, including meristem-derived sig

87 ally distinct organs from a common olfactory primordium are unknown.

88 We show that the siphon primordium arises within a non-dividing field of lateral

89 ition such that they fuse with the migrating primordium as it advances, and later contribute to the l

90 sociate tightly with the invaginating midgut primordium as it enters the embryo; however, in embryos

91 a progenitor pool at the leading zone of the primordium as neuromasts are deposited from the trailing

92 tial formation of the posterior lateral line primordium, as well as during organ patterning, migratio

93 produces Hh and is near the tracheal air sac primordium (ASP) and myoblasts.

94 The Drosophila Dorsal Air Sac Primordium (ASP) is a tracheal tube that grows toward Br

95 es for development of the Drosophila air sac primordium (ASP).

96 during the development of the larval Air-Sac-Primordium (ASP).

97 and transported by cytonemes to the air sac primordium (ASP).

98 cytonemes in order to signal to the air sac primordium (ASP).

99 o and reside in the epithelium of the tongue primordium at an early embryonic stage, acquire epitheli

100 the most enriched gene in the mouse thyroid primordium at E10.5.

101 onnecting the neural tube lumen to the mouth primordium at larval stages.

102 ng growth during larval life ceases when the primordium attains full size, concomitant with the larva

103 gynoecium requires that the early gynoecial primordium be partitioned into distinct spatial domains

104 The eye primordium begins with a default ventral fate, on which

105 hat controls cell proliferation at the petal primordium boundaries.

106 tissue, the zebrafish posterior lateral line primordium, buffers its attractant in this concentration

107 mation of the midvein, and appearance of the primordium bulge.

108 e architecture of the larval fan-shaped body primordium but did not result in gross abnormalities of

109 Barx1 is absent from the spleen primordium but highly expressed in the mesogastrium, ind

110 rface area expansion throughout the cortical primordium but no gyrification.

111 formation, IRX3/5 help to shape the limb bud primordium by promoting the separation and intercalation

112 ons support a key role played by superficial primordium cells and the skin in directed migration of t

113 We describe a superficial population of flat primordium cells that wrap around deeper epithelialized

114 enes expressed in the Drosophila CNS midline primordium cells, and show that while the expression pat

115 ubular eggshell appendages is derived from a primordium comprising two distinct cell types.

116 (2) The C-shaped primordium contains a characteristic balloon-like capill

117 The cerebellar primordium contains two germinative zones, the rhombic l

118 The gonad primordium contains two PGCs that are wrapped individual

119 system, epithelial cells within a cyst-like primordium develop diverse shapes through largely unknow

120 icum infection process, initiation of nodule primordium development, and subsequent nodule organogene

121 he earliest steps leading up to lateral root primordium development.

122 he parathyroid-specific domain in the common primordium did not express Pth and could not maintain th

123 xus region, which we termed Di-Mesencephalic primordium (DiMes).

124 proliferating progenitor cells and eventual primordium disorganization.

125 In aly/aly mice, the LN primordium dissipates irreversibly late in gestation; in

126 We show that laser ablation of atrial primordium ectoderm also results in a failure to form gi

127 ired JAG and were genetically separable from primordium emergence.

128 ing gradient is initiated at the rear of the primordium, equilibrates across the primordium within 20

129 The cells of the claustrum primordium express Nr4a2; they are formed in combination

130 us, Single-minded directly regulates midline primordium-expressed genes, but in some cases plays a pr

131 trol expression of most, if not all, midline primordium-expressed genes, the role of Notch in directl

132 In contrast, midline primordium expression of other genes shows a strong depe

133 Midline primordium expression of the rhomboid gene is dependent

134 t that Wg controls the expansion of the wing primordium following D-V segregation by fueling this aut

135 e that Wg promotes the expansion of the wing primordium following the D-V segregation by fueling this

136 ession patterns in the first branchial arch (primordium for jaw) and mutant phenotypes; inactivation

137 Germinal matrix (GM), a key primordium for the brain reward circuitry, is unique amo

138 candidate enhancers from the maxillary arch (primordium for the upper jaw) of mouse embryos.

139 I4KIIIbeta1 and PI4KIIIbeta2 induced both LR primordium formation and endocytic trafficking toward th

140 role of PI4KIIIbeta1 and PI4KIIIbeta2 in LR primordium formation in Arabidopsis.

141 in receptor 1, which is essential for nodule primordium formation, and the B-type response regulator

142 hizobia but had significantly reduced nodule primordium formation, suggesting that auxin hypersensiti

143 These indicate that, after lung primordium formation, Wnt signaling is not essential for

144 ivity constitutively negatively regulates LR primordium formation.

145 mbryonic mandibular condylar growth and disc primordium formation.

146 ignaling in the pericycle to initiate nodule primordium formation.

147 m-adjacent pericycle, but did not rescue the primordium formation.

148 ells found in dgt1-1 roots were unrelated to primordium formation.

149 nd LHK3 to mediate cell divisions for nodule primordium formation.

150 nd captured time-lapse movies as the gonadal primordium formed.

151 are established and maintained when the lung primordium forms and starts to branch.

152 cts reprogramming from transit amplifying to primordium founder cell fate in Arabidopsis inflorescenc

153 FGF8 diffuses through the mouse neocortical primordium from a discrete source in the anterior telenc

154 enables the coalescence of the lateral line primordium from an initial fuzzy pattern into a compact

155 tc-independent function protects the retinal primordium from Hh activity, defines the stalk/retina bo

156 led by RA that lead to formation of the lung primordium from the primitive foregut remain unclear.

157 least in the apical portion of the gynoecial primordium, from obtaining medial fates.

158 monstrate that shade-induced changes in leaf primordium gene expression largely do not overlap with t

159 The rear of the primordium generates this gradient through continuous se

160 lopment: whether the axillary bud, or branch primordium, grows out to give a lateral shoot or remains

161 ions at the interface between patterning and primordium growth in Arabidopsis flowers.

162 (RA) is essential for formation of the lung primordium; however, little is known about the impact of

163 th a role in the transition from meristem to primordium identity, JAG directly repressed the meristem

164 The somatopleure is the amniotic primordium in amniote development, but its boundary to t

165 ich instructs the formation of the adult eye primordium in Drosophila.

166 Analysis of the 3rd pouch-derived primordium in Gcm2-/- mutants showed the parathyroid-spe

167 leaves, suggesting that the terminal leaflet primordium in M. truncatula has a unique developmental m

168 e protrusions prior to fusion of a key organ primordium in mammalian development.

169 n surrounding cells to join the growing wing primordium in response to Wg.

170 are formed in the deep part of the claustrum primordium in the lateral pallium, but they migrate vent

171 hyroid glands arise from a shared endodermal primordium in the third pharyngeal pouch (3rd pp).

172 ntiated axon tracts of these lineages form a primordium in which all of the compartments of the centr

173 three regulatory cells of the somatic gonad primordium in young larvae.

174 The posterior lateral line primordium in zebrafish provides an amenable model to st

175 expressed in the genital ridge (the gonadal primordium) in both sexes and then becomes testis-specif

176 essed in the neural crest-derived hyoid bone primordium, in addition to mesoderm-derived osteochondra

177 quent impaired growth of the caudal cortical primordium, including the hippocampus.

178 negative receptor in the central neocortical primordium induced cells to adopt a more posterior area

179 nt larvae (Lgl) tumor suppressor in the wing primordium induced epithelial neoplasia in its Homothora

180 This LR primordium induction was alleviated by exogenous PI4P, s

181 witch is ideally suited for iterative flower primordium initiation and orchestrates additional auxin-

182 flow during the earliest stages of gynoecial primordium initiation and outgrowth.

183 us reveals a mechanistic link between flower primordium initiation and subsequent steps in flower mor

184 th compound leaves, the positions of leaflet primordium initiation are associated with local peaks of

185 tribution of gene repression to reproductive primordium initiation is poorly understood.

186 MP that furthermore jointly regulate flower primordium initiation.

187 al root formation by inhibiting lateral root primordium initiation.

188 NA for induction of key regulators of flower primordium initiation.

189 gans somatic gonad develops from a four-cell primordium into a mature organ that differs dramatically

190 iven mechanisms to convert a two-dimensional primordium into a three-dimensional structure, and provi

191 t the transformation of this two-dimensional primordium into a tube involves out-of-plane bending fol

192 al development, patterning events divide the primordium into distinct domains that will give rise to

193 act as a binary switch to subdivide the wing primordium into PE and DP, and assign crucial roles for

194 generation of boundaries to divide an organ primordium into smaller fields.

195 The initial steps of atrial primordium invagination are similar to otic placode inva

196 Drosophila mesoderm layer from an epithelial primordium involves a transition to a mesenchymal state

197 The periodic lengthening of the primordium is controlled by Wnt/beta-catenin/Fgf-depende

198 The Drosophila wing primordium is defined by expression of the selector gene

199 Thus, directed migration of the primordium is dependent on a close match between the Cxc

200 Initially, the cerebellar primordium is divided into five cardinal lobes, which ar

201 onset of migration, the compact state of the primordium is not fully established, as isolated cells w

202 in-rich CR cells that covers the neocortical primordium is not required to direct layer order.

203 ate Xenopus, we find that although the mouth primordium is not topologically continuous with the neur

204 The pLL primordium is organized into polarized rosettes represen

205 uent maintenance and growth of the adult eye primordium is regulated partly by redundant and partly b

206 we propose that Hh signaling from the brain primordium is required for proper specification of the s

207 PDX1+ ventral pancreas and a SOX17+ biliary primordium is Sox17-dependent.

208 l (D) and ventral (V) compartments, the wing primordium is specified by activity of the selector gene

209 Early in development, the wing primordium is subdivided into a thin layer of peripodial

210 auxin application to a single side of a leaf primordium is sufficient to recapitulate the asymmetries

211 m indeterminate meristem to determinate leaf primordium is the down-regulation of KNOX1 genes ortholo

212 localizes adjacent to the developing gonadal primordium, is required to prevent the SGPs from over-ex

213 zebrafish met is expressed in the cerebellar primordium, later localizing to the ventricular zone (VZ

214 his study, we use the zebrafish lateral line primordium (LLP), a group of migrating epithelial cells

215 However, early LR primordium (LRP) morphogenesis is not fully understood.

216 emergence requires the outgrowth of the new primordium (LRP) to coincide with the timely separation

217 ete sensory patches during evolution of this primordium may be related to subdivision of an early pan

218 The Zebrafish Posterior Lateral Line primordium migrates in a channel between the skin and so

219 ractions between these two pathways regulate primordium migration and prosensory organ formation.

220 en we increase the K(d) of Cxcl12 for Cxcr4, primordium migration is less directional.

221 or rosette formation, atoh1a expression, and primordium migration.

222 il of Ackr3 also results in less directional primordium migration.

223 signaling, however the rescue of cerebellar primordium morphogenesis is independent of both Gbx and

224 , with msbA2 mutant cells stimulating nodule primordium morphogenesis, but failing to invade plant ti

225 fan-shaped body primordium, the posterior EB primordium moves forward and merges with the anterior EB

226 These results suggest that all cells in the primordium need to sense the attractant and adhere to ea

227 uting, and the migration of the lateral line primordium, neural crest cells, or head mesendoderm.

228 rom a rostromedial source in the neocortical primordium (NP), forms a rostral-to-caudal (R/C) gradien

229 d of FGF8 signaling in the mouse neocortical primordium (NP), the NP was the same size in ferret and

230 te the left and right sides of an initiating primordium occupying niches that differ in their distanc

231 nalysis of gene expression in the cerebellar primordium of E11.5 Neurog1 null (Neurog1-/-) mice to id

232 (1) The glomerular primordium of medaka - unlike the one of zebrafish - exh

233 The primordium of the Arabidopsis (Arabidopsis thaliana) gyn

234 macrophages in the endocardial cushion, the primordium of the cardiac valves.

235 cells include the first neurons seen in the primordium of the cerebral cortex, before the onset of l

236 The primordium of the EB has a complex composition.

237 dence of autocrine Hh signaling in the optic primordium of the embryo.

238 the head to form the otic vesicle (OV), the primordium of the inner ear and CVG.

239 In higher vertebrates, the primordium of the nervous system, the neural tube, is sh

240 ression is restricted to Rathke's pouch, the primordium of the pituitary gland.

241 The optic vesicle is a multipotential primordium of the retina, which becomes subdivided into

242 plex developmental program that connects the primordium of the upper urinary tract [the nephric duct

243 em is afforded by the migrating lateral line primordium of the zebrafish.

244 A leaf undergoes determinate growth from a primordium on flank of the shoot apical meristem.

245 at Lef1 function is not required for initial primordium organization or migration, but is necessary f

246 broblast growth factor (FGF) source controls primordium organization, which, in turn, regulates the p

247 t in the anterior foregut where the tracheal primordium originates and targeted ablation of Bmp4 (Bmp

248 vatives, including the palps and oral siphon primordium (OSP).

249 hem, hippocampal primordium and neocortical primordium overexpand, while production of Cajal-Retzius

250 Surprisingly, the overall primordium patterning, as assayed by the expression of v

251 The posterior lateral line primordium periodically deposits prosensory organs as it

252 catenin signaling in the leading zone of the primordium plays a crucial role in orchestrating lateral

253 Here, we study the posterior lateral line primordium (PLLP) a group of about 100 cells, destined t

254 ells in the zebrafish posterior lateral line primordium (PLLp) along a path defined by Cxcl12a expres

255 Migration of the posterior lateral line primordium (pLLP) generates the zebrafish sensory organs

256 The posterior lateral line primordium (PLLp) migrates caudally and periodically dep

257 The posterior lateral line primordium (pLLp) migrates caudally, depositing neuromas

258 Wnt signaling in the posterior lateral line primordium (pLLP), a cohort of ~100 cells that collectiv

259 tion in the zebrafish posterior lateral line primordium (pLLp), a group of approximately 100 cells th

260 Wnt/beta-catenin and Fgf signaling maintain primordium polarity by differential regulation of gene e

261 l cortex and gonad are derived from the same primordium present during early urogenital development.

262 In the developing cortical primordium, RACK1 protein is expressed in a high-rostrom

263 n canal that conducts rhizobia to the nodule primordium requires a functional Rab GTPase located in G

264 ssed in the leading and trailing part of the primordium, respectively.

265 Likewise, neoplasia in the eye primordium resulted in loss of Elav, a retinal cell mark

266 on of both Foxa1 and Foxa2 in the pancreatic primordium results in complete loss of Pdx1 expression a

267 al root emergence but, intriguingly, not for primordium specification itself.

268 he 'Dlx codes' appear to regionalize the jaw primordium such that Dlx1/2 regulate upper jaw developme

269 tor of this process in the mouse hippocampal primordium, such that Lhx2 overexpression promotes neuro

270 e was found expressed in the vascular vessel primordium, suggesting KANK genes are a component of the

271 myogenic progenitors migrate into the tongue primordium, suggesting that CNC cells play an instructiv

272 onad are thought to be derived from a common primordium that divides into separate tissues during emb

273 omain is restricted to a small region of the primordium that gives rise to the trap's inner layer.

274 in zebrafish, which is formed by a cohesive primordium that migrates from head to tail and deposits

275 After sex is determined in the gonadal primordium the global sex determination pathway is dispe

276 ed from its initial creation by an embryonic primordium, the blastema that emerges at the injury site

277 t as an integral part of the fan-shaped body primordium, the posterior EB primordium moves forward an

278 texts, such as in the zebrafish lateral line primordium, the vertebrate pancreas, the Drosophila epit

279 he development of the tunicate atrial siphon primordium, thought to share homology with the vertebrat

280 other sources did not invade the neocortical primordium to compensate for hem loss.

281 e the expression of Sf1 in the adrenogonadal primordium to ensure adrenal development.

282 sink in the migrating zebrafish lateral line primordium to generate SDF1 gradients.

283 It is first required for the mesoderm primordium to lose its epithelial polarity.

284 Thus, DNA methylation primes the prostate primordium to respond to developmental cues mediating ou

285 Cells throughout the Drosophila wing primordium typically show subcellular localization of th

286 tedly caudal and noncontiguous to cerebellar primordium; ventral CN subdivisions arise from more rost

287 -MyoII are induced in a spatially restricted primordium via localized transcription of the G-protein-

288 maize PIN1 expression at the incipient leaf primordium was greatly reduced in abph1 mutants.

289 The earliest claustral primordium was identified superficially, dorsal to the o

290 ent of the mechanically induced lateral root primordium was independent of an auxin supply from the s

291 events that lead to formation of the gonadal primordium, we generated transgenic strains to label the

292 NC)-derived ectomesenchyme in the mandibular primordium where intramembranous ossification takes plac

293 The simple Caenorhabditis elegans gonadal primordium, which contains two somatic gonad precursors

294 es: Fgf signalling attracts them towards the primordium, which counteracts Sdf1alpha/Cxcr4b-mediated

295 ion factor (TF) gradients in the neocortical primordium, which define a "protomap" in the embryonic v

296 The NMs are deposited by a migrating pLL primordium, which is organized into polarized rosettes (

297 DALv2 neurons form the anterior EB primordium, which starts out as a bilateral structure, t

298 are deposited from the trailing part of the primordium, while progenitor cells in the leading part g

299 r of the primordium, equilibrates across the primordium within 200 min, and operates near steady stat

300 morphogenesis to give rise to the cerebellar primordium within which the various cerebellar neuron ty