ライフサイエンスコーパス: pro-inflammatory

1 anzyme B, suggesting that CD151+ T cells are pro-inflammatory.

2 Recombinant CD163 abolished the pro-inflammatory actions of TWEAK on vascular smooth mus

3 transcripts (e.g. CD11c, CD47 and CD36) and pro-inflammatory activation genes (e.g. Tlr4 and Il1b).

4 However, macrophage pro-inflammatory activation must be under exquisite cont

5 er age 65, with men having higher innate and pro-inflammatory activity and lower adaptive activity.

6 omote the metabolic syndrome generally cause pro-inflammatory alterations in microbiota communities i

7 endometriosis as demonstrated by changes in pro-inflammatory and angiogenic mediators.

8 enetic deletion of YAP/TAZ leads to impaired pro-inflammatory and enhanced reparative response.

9 Consistently, YAP activation enhanced pro-inflammatory and impaired reparative response.

10 beta accumulates rapidly and drives a potent pro-inflammatory and neurodegeneration-related gene prog

11 liflozin treatment attenuates pro-oxidative, pro-inflammatory and pro-apoptotic signaling mediated by

12 uates the expression of SERPINE1, a critical pro-inflammatory and pro-fibrotic gene.

13 up of toxic lipid species, which worsens the pro-inflammatory and pro-fibrotic shift observed in nona

14 ocytes aged in culture develop a spontaneous pro-inflammatory and senescence-like phenotype.

15 at least, in part, to the conversion of the pro-inflammatory angiotensin (Ang) II peptide into angio

16 dases such as CD39 and CD73, which hydrolyse pro-inflammatory ATP to generate immunosuppressive adeno

17 ping embryonic mouse brain that manifests as pro-inflammatory cerebrospinal fluid (CSF) and accumulat

18 ress, expression of antioxidant enzymes, and pro-inflammatory chemokine in human bronchial epithelial

19 ion of NF-kappaB and consequent secretion of pro-inflammatory chemokine, CXCL1.

20 we show that lung macrophages polarize to a pro-inflammatory, classically activated phenotype after

21 using resolution pharmacology to convert the pro-inflammatory condition into a non-inflammatory one,

22 in a manner representative of thrombotic or pro-inflammatory conditions such as arterial thrombosis.

23 er, individual cells' signaling responses to pro-inflammatory cues are heterogeneous, with subpopulat

24 metry were used to determine the presence of pro-inflammatory cytokine expressing monocytes and monoc

25 adation, prevents Toll-like receptor-induced pro-inflammatory cytokine expression, and represents an

26 pid and macrophage content, plaque size, and pro-inflammatory cytokine expression.

27 of osteogenic genes, decreased expression of pro-inflammatory cytokine genes, and increased abundance

28 ngenuity pathway analyses also suggested the pro-inflammatory cytokine IL-17A to regulate the vaginal

29 tion, resident islet macrophages release the pro-inflammatory cytokine IL-1beta, to levels that are s

30 ling caused by chronic overexpression of the pro-inflammatory cytokine IL-6.

31 ceftriaxone in reducing the secretion of the pro-inflammatory cytokine IL-8 by endocervical cells inf

32 From a panel of 10 cytokines, the pro-inflammatory cytokine IL-8 exhibited a strong correl

33 ential mediator is interleukin-17 (IL-17), a pro-inflammatory cytokine implicated in neurodevelopment

34 ple volumes, as shown for the detection of a pro-inflammatory cytokine in mouse interstitial fluid an

35 g revealed increased immunoreactivity of the pro-inflammatory cytokine Interleukin-1beta (IL-1beta) i

36 Blood of patients with PTA showed a higher pro-inflammatory cytokine level compared to the samples

37 Increased pro-inflammatory cytokine levels and proliferation of ac

38 vels are enhanced, leading to a reduction in pro-inflammatory cytokine levels.

39 ough p63-mediated activation of enhancers at pro-inflammatory cytokine loci, which includes IL1A and

40 in adipose tissue-mediated inflammation and pro-inflammatory cytokine production, a shift towards ke

41 xic condition showed increased permeability, pro-inflammatory cytokine production, and increased oxid

42 o found that rolipram inhibits organ damage, pro-inflammatory cytokine production, and intracellular

43 affects LPS, but not monophosphoryl lipid A, pro-inflammatory cytokine production.

44 Pro-inflammatory cytokine profile and multiple markers o

45 lyses, we discovered that PGA-FLUO inhibited pro-inflammatory cytokine release, suggesting that polyp

46 Functional enrichment analysis revealed pro-inflammatory cytokine signaling pathways as dysregul

47 Pro-inflammatory cytokine stimulation increased the cell

48 TNF is a highly pro-inflammatory cytokine that contributes not only to t

49 ion of interferon beta (IFNbeta), which is a pro-inflammatory cytokine that plays a major role in APC

50 ked reductions in the chemokine Ccl2 and the pro-inflammatory cytokine Tnfalpha were observed at the

51 Notably, both visceral fat and the pro-inflammatory cytokine tumor necrosis factor alpha co

52 CD163 can also bind to the pro-inflammatory cytokine TWEAK.

53 Interleukin-17A (IL-17A) is a pro-inflammatory cytokine with well-characterized biolog

54 r (GM-CSF), a myelopoietic growth factor and pro-inflammatory cytokine, plays a critical role in alve

55 attenuation of aortic diameter, decrease in pro-inflammatory cytokines (IL-1beta, IL-6, IL-17, MCP-1

56 Both in vitro and in vivo, the expression of pro-inflammatory cytokines (IL-6, IL-1beta, and TNF-alph

57 increased indistinctively the production of pro-inflammatory cytokines (IL-8, IL-1beta, and IL-6).

58 transcriptome, suppressed the production of pro-inflammatory cytokines (including interleukin-6, tum

59 surface charges displayed on the majority of pro-inflammatory cytokines (negative) and anti-inflammat

60 ated early/acute inflammation by suppressing pro-inflammatory cytokines (TNF-alpha, IL-1beta, CCL-3 a

61 is characterized by excessive production of pro-inflammatory cytokines and acute lung damage associa

62 press increased levels of KLF2, produce less pro-inflammatory cytokines and adhesion molecules.

63 nt inflammatory cells, and the production of pro-inflammatory cytokines and adhesion molecules.

64 by a significant reduction in the levels of pro-inflammatory cytokines and an increase in IgA levels

65 was paralleled by elevated levels of several pro-inflammatory cytokines and chemokines in ascites flu

66 LPS activated mRNA expression of different pro-inflammatory cytokines and chemokines in time- and c

67 lf-regulated and modulated the expression of pro-inflammatory cytokines and chemokines.

68 s) potentiate neuronal activity by releasing pro-inflammatory cytokines and neuroactive compounds.

69 rs along a continuum from reliance on innate pro-inflammatory cytokines and stress-induced host ligan

70 active agents in soy and tomatoes can reduce pro-inflammatory cytokines and suppressive immune popula

71 Elevated pro-inflammatory cytokines exist in both blood and brain

72 ter three days of treatment was detected for pro-inflammatory cytokines IL-1beta, IL-2, IL-6, IL-8 an

73 nti-inflammatory cytokine IL-10, but not the pro-inflammatory cytokines IL-6 or IL-21, is required vi

74 re largely not affected by STEMI, except for pro-inflammatory cytokines IL-6, IL-18, and MIG, as well

75 st ivermectin induced NLRP3 inflammasome and pro-inflammatory cytokines in cultured human proximal tu

76 vated B cells activity and the production of pro-inflammatory cytokines in P. gingivalis-stimulated i

77 k after acute lung injury (ALI) express more pro-inflammatory cytokines in their brainstem respirator

78 uman psoriasis while also lowering levels of pro-inflammatory cytokines in tissue and serum.

79 The pattern of pro-inflammatory cytokines induced in COVID-19 has simil

80 7, Nestin, Sox2, and PAX6), reduction of the pro-inflammatory cytokines INFG, IL1A, and IL12P70 throu

81 models of HF, central inhibition of RAS and pro-inflammatory cytokines normalizes sympathetic drive

82 a, and decreases the expression of important pro-inflammatory cytokines of Th1 and Th17 profiles, whi

83 sociated with elevated circulating levels of pro-inflammatory cytokines opened a new area of research

84 activation and production of type I IFN and pro-inflammatory cytokines stimulated by TLR7/9 ligands.

85 Caspase-1 cleaves and activates the pro-inflammatory cytokines such as IL-1beta and IL-18 an

86 On the contrary, pro-inflammatory cytokines such as tumor necrosis factor

87 ptive immune systems, with pivotal roles for pro-inflammatory cytokines such as tumour necrosis facto

88 s in adipose tissue, resulting in release of pro-inflammatory cytokines that impair lipolysis suppres

89 Stimulation increased the pro-inflammatory cytokines TNF-alpha, IFN-gamma, and IL-

90 loproteinases (MMPs), increase expression of pro-inflammatory cytokines TNFalpha, IL-1beta, and IL-8,

91 nuates chemotherapy-induced secretion of the pro-inflammatory cytokines TNFalpha, IL-1beta, and IL-8.

92 activated fibroblasts produce high levels of pro-inflammatory cytokines to promote metastatic cancer

93 Higher secretion of pro-inflammatory cytokines was seen in colonoids infecte

94 d independently of disease severity, whereas pro-inflammatory cytokines were only acutely produced.

95 mune activity, including increased levels of pro-inflammatory cytokines(3,4) that may be produced by

96 tates intrauterine UP infection, upregulates pro-inflammatory cytokines, and increases preterm birth

97 rotein levels, BAL inflammatory cell counts, pro-inflammatory cytokines, and pulmonary function (tota

98 RS-CoV-2 can lead to excessive production of pro-inflammatory cytokines, but the production of type I

99 nt capacity and suppressed the expression of pro-inflammatory cytokines, iNOS, IL6, and IL1beta, comp

100 y M1-like microglia and increased release of pro-inflammatory cytokines.

101 ation, foam cell formation and expression of pro-inflammatory cytokines.

102 umors in vivo and reduced systemic levels of pro-inflammatory cytokines.

103 ins and crucially, a range of anti-viral and pro-inflammatory cytokines.

104 tory diseases by mediating the expression of pro-inflammatory cytokines.

105 igh mortality due to sustained production of pro-inflammatory cytokines.

106 efore, we used a hemoadsorber (HA) to remove pro-inflammatory cytokines.

107 ocytes do not express substantial amounts of pro-inflammatory cytokines.

108 pffer cells to gp96 induced the secretion of pro-inflammatory cytokines.

109 nvestigate the relationship between MetS and pro-inflammatory diet by using the food inflammation ind

110 y was higher in IBD participants with a more pro-inflammatory diet with statistical significance in C

111 DII was 0.71 +/- 1.33, suggesting a slightly pro-inflammatory diet.

112 ycolysis, which directly triggers an M1-like pro-inflammatory differentiation and nutritional innate

113 S-evoked activation produces either anti- or pro-inflammatory effects due to disease-state-dependent

114 e disease, our results also suggest that the pro-inflammatory effects of these agents should be close

115 he microglial IL-10 receptor counteracts the pro-inflammatory effects of TNF to allow restoration of

116 t TAC or PS alone attenuated the LPS-induced pro-inflammatory effects reducing cells and proteins in

117 erimental arthritis models demonstrating its pro-inflammatory effects, made this cytokine a strong ca

118 ay inflammation, and increased production of pro-inflammatory eicosanoids.

119 this decrease might be a consequence of the pro-inflammatory environment in asthma or in response to

120 (CSF-1) promotes placentation and creates a pro-inflammatory environment that is fundamental for the

121 Our findings suggest that pro-inflammatory events including acute cellular rejecti

122 and nonallergic stimuli, leading to several pro-inflammatory events, including eosinophil activation

123 f adenosine but also on the stabilization of pro-inflammatory extracellular ATP to restore antitumour

124 The pro-inflammatory factor Activin has been implicated as a

125 ranscription factor, up-regulating the major pro-inflammatory factor, pro-IL-18.

126 phatase-1 (SHIP-1) is a target of miR-155, a pro-inflammatory factor.

127 t with RSV and insulin reduced the levels of pro-inflammatory factors (either proteins or mRNA) and i

128 and M13 (at 1.0 mug/mL) could down-regulate pro-inflammatory factors (TNF-alpha, IL-1beta, and IL-6)

129 Both pro-inflammatory factors and viruses may cross the blood

130 In this scenario, pro-inflammatory factors are intensely released into the

131 ed groups, and mRNA levels of angiogenic and pro-inflammatory factors in ripasudil-treated grafted co

132 iltration, and mRNA levels of angiogenic and pro-inflammatory factors in the grafted cornea and drain

133 It remains poorly understood whether pro-inflammatory factors released from non-cardiac tissu

134 have identified increased systemic levels of pro-inflammatory factors, including interleukin-6, tumor

135 mediators (SPMs) like resolvin D1 (RvD1) and pro-inflammatory factors, like leukotriene B(4) (LTB(4))

136 also significantly decreased mRNA levels of pro-inflammatory factors, without alteration of anti-inf

137 ons of intravenous lipid emulsions to reduce pro-inflammatory fatty acids and plant sterol content, c

138 ssed dams that are primarily associated with pro-inflammatory function.

139 P2X7Rs) are unique purinergic receptors with pro-inflammatory functions.

140 controls but chronic immune infiltrates and pro-inflammatory gene activation, including NF-kB phosph

141 appaB signaling completely reversed elevated pro-inflammatory gene expression in macrophages.

142 hat of Treg cells, and promoted a heightened pro-inflammatory gene expression signature.

143 cing gut microbiota disruption, aberrant gut pro-inflammatory gene expression, and dopaminergic neuro

144 ies reduced remodeling along with matrix and pro-inflammatory gene expression.

145 mine if BER activity of OGG1 is required for pro-inflammatory gene expression.

146 or of inflammation, which broadly attenuates pro-inflammatory gene programs in macrophages.

147 rains NFkappaB activation and curtails broad pro-inflammatory gene programs in myeloid cells.

148 rophages and neutrophils and upregulation of pro-inflammatory genes (TNF-alpha, IL-1beta and Cxcl-1)

149 on was associated with the downregulation of pro-inflammatory genes and the upregulation of anti-infl

150 peptide LP17 resulted in decreased levels of pro-inflammatory genes for the moderate and severe isola

151 ranscription of the cytoprotective Hmox1 and pro-inflammatory genes Il1b and Nos2, leading to a moder

152 r binding protein beta (c/EBPbeta) regulates pro-inflammatory genes in microglia and is upregulated i

153 e in global transcription, including that of pro-inflammatory genes.

154 ed activation of NF-kappaB and expression of pro-inflammatory genes.

155 ation and expression of psoriasis-associated pro-inflammatory genes.

156 bles naive CD4 T cells to differentiate into pro-inflammatory helper T cells that are prone to invade

157 ntly had vascular events in the context of a pro-inflammatory hypercoagulable state with elevated C-r

158 g has been recommended in the context of the pro-inflammatory, hypercoagulable background milieu.

159 umatoid arthritis display a shift toward the pro-inflammatory IgA2 subclass, which is associated with

160 by neutrophilic pustulosis and triggered by pro-inflammatory IL-36 cytokines in skin.

161 , survival, and phagocytosis, and diminished pro-inflammatory immune cell activation; data that ident

162 stress persisting for weeks or more promotes pro-inflammatory immune dysregulation, a risk factor for

163 evelopment of therapeutic agents to modulate pro-inflammatory immune reactions.

164 The natural history of the pro-inflammatory immune response after aSAH has not been

165 entral nervous system (CNS) accompanied by a pro-inflammatory immune response in many of its hosts, i

166 he absence of IFD, can result in deleterious pro-inflammatory immune responses.

167 est that FMT might reduce Candida to contain pro-inflammatory immunity during intestinal disease and

168 torically, these DAMPs have been shown to be pro-inflammatory in nature.

169 ations that syndecan-3 (SDC3) is selectively pro-inflammatory in the joint led us to hypothesise that

170 species, representative strains of which are pro-inflammatory in vitro, are also associated with immu

171 e exposed to milk pellets, and levels of the pro-inflammatory interleukin IL8 were measured.

172 intestinal adherence, biofilm formation, and pro-inflammatory interleukin-8 secretion compared with S

173 hyaluronidases, such as HYAL-1 resulting in pro-inflammatory low-molecular weight fragments.

174 sputum eosinophilia was in line with higher pro-inflammatory LTE(4) in ISS and the highest logLTE(4)

175 with enhanced differentiation of MDSCs into pro-inflammatory M1 macrophages in LuM, indicated that M

176 plasticity in switching between classically (pro-inflammatory-M1) and alternatively activated (anti-i

177 Vitamin D deficiency causes pro-inflammatory macrophage infiltration in metabolic ti

178 arker CD45 and even greater reduction of the pro-inflammatory macrophage receptor CD36 suggest not on

179 ages, MaR1 treatment decreased the number of pro-inflammatory macrophages within the fracture callus

180 t functions of distinct NF-kappaB factors in pro-inflammatory macrophages, revealing the association

181 ubiquitinated in lipopolysaccharide-induced pro-inflammatory macrophages, which was enhanced in ITCH

182 BP), renal hypoxia, and renal vein levels of pro-inflammatory marker tumor necrosis-factor (TNF)-alph

183 Conversely, mRNA levels of pro-inflammatory markers (IL-6, IL-1beta, COX-2 and TNF-

184 There was increased expression of pro-inflammatory markers in cortex of TBI + Sp compared

185 was associated with increased expression of pro-inflammatory markers PTX3, CXCL1, CXCL6, CXCL8, and

186 he net cerebral release of pro-oxidative and pro-inflammatory markers will be elevated in hyperthermi

187 es, PTX3+ cells co-expressing high levels of pro-inflammatory markers, APOD+ fibro-adipogenic progeni

188 In the oral cavity, pro-inflammatory mechanisms induced by pathogenic bacter

189 gh stabilization of IkappaB-zeta, a critical pro-inflammatory mediator in chondrocytes.

190 us astrocyte functions (i.e., proliferation, pro-inflammatory mediator production, regulatory mechani

191 interleukin-1alpha (IL-1alpha), an important pro-inflammatory mediator, was specifically ubiquitinate

192 ile simultaneously triggering the release of pro-inflammatory mediators and increasing tumour-infiltr

193 both LL-37- and KLK-5-induced expression of pro-inflammatory mediators and suppressed the activation

194 cytokine, in turn, attenuated production of pro-inflammatory mediators and, ultimately, macrophage-m

195 rinsulinemia promotes the release of soluble pro-inflammatory mediators from macrophages that lead to

196 ogether, our data suggest that adsorption of pro-inflammatory mediators from the perfusate represents

197 wever, the NF-kappaB-dependent production of pro-inflammatory mediators is not affected by C/EBPgamma

198 uenzae, low diversity measures and increased pro-inflammatory mediators when compared to the larger H

199 resses LPS- and IgG immune complexes-induced pro-inflammatory mediators' production through the downr

200 HP group had significantly higher levels of pro-inflammatory mediators, NF-kappaB expression and apo

201 oprotective effects through the reduction of pro-inflammatory mediators, nuclear receptor NF-kappaB e

202 ttention to how immune cells chemotax toward pro-inflammatory mediators, presenting a model for cell

203 be linked to a decrease in the production of pro-inflammatory mediators, such as TNF-alpha and IL-6.

204 and elevated expression of LDL receptor and pro-inflammatory mediators.

205 e in tachykininergic activity and release of pro-inflammatory mediators.

206 ppaB to promote the extracellular release of pro-inflammatory mediators.

207 There is strong evidence that the pro-inflammatory microenvironment during post-partum mam

208 changes in the pancreatic environment from a pro-inflammatory microenvironment that favors the develo

209 d immunomodulation evident by a reduction in pro-inflammatory microglia and macrophages.

210 Here, we asked whether pro-inflammatory microglial/macrophage activation is req

211 an anti-tumor immune response by increasing pro-inflammatory modulators.

212 and the fact that it acts as a hemolytic and pro-inflammatory molecule.

213 ce that is characterized by the secretion of pro-inflammatory molecules that promote the functional d

214 vivo techniques, we showed that circulating pro-inflammatory myeloid cells accumulated in atheroscle

215 The highly pro-inflammatory nature of alphavirus disease has sugges

216 rosis (ALS) is a multifactorial, multisystem pro-inflammatory neuromuscular disorder compromising mus

217 Whereas IgA2 acts pro-inflammatory on neutrophils and macrophages, IgA1 do

218 n (IFN)-mediated antiviral responses precede pro-inflammatory ones, optimizing host protection and mi

219 depend on their polarization to exert either pro-inflammatory or anti-inflammatory effects.

220 Macrophage polarization to either a pro-inflammatory or anti-inflammatory status is controll

221 be attributed to specific cellular subsets: pro-inflammatory or classical monocytes (Ly6c(Hi)) and p

222 under conditions of lipopolysaccharide (LPS) pro-inflammatory or IL-4 anti-inflammatory stimulation r

223 d TAZ is increased in macrophages undergoing pro-inflammatory or reparative phenotype changes.

224 al for cardiac repair as they can adopt both pro-inflammatory or reparative phenotypes to modulate in

225 important regulators of macrophage-mediated pro-inflammatory or reparative responses post-MI.

226 , the NLRP3 inflammasome is part of a larger pro-inflammatory pathway, whose modulation is also being

227 Thus, pro-inflammatory pathways are likely an important mechan

228 role of asymptomatic hyperuricaemia in these pro-inflammatory pathways.

229 Our study shows that pro-inflammatory phagocytic signaling is required for my

230 phages from aged mice protected cells form a pro-inflammatory phenotype and induced an anti-inflammat

231 ress, which can lead to the development of a pro-inflammatory phenotype that can be associated with c

232 ss of a single allele of Cebpb prevented the pro-inflammatory phenotype.

233 -compliant stiff substrates, often display a pro-inflammatory phenotype.

234 on of IL-1alpha is associated with increased pro-inflammatory polarization of macrophages deficient i

235 Finally, IL-1alpha neutralization attenuated pro-inflammatory polarization of the ITCH-deficient macr

236 f the mature form of IL-1alpha and exhibited pro-inflammatory polarization, and reduced deubiquitinat

237 Observations include perturbations of pro-inflammatory, pro-fibrotic and oxidative stress mark

238 systemic immune system-dependent factors and pro-inflammatory processes in KC development or progress

239 ion, but also enhances the activation of the pro-inflammatory RAC1/ROS/NLRP3/IL-1beta axis.

240 We show that YAP/TAZ promote pro-inflammatory response by increasing interleukin 6 (I

241 We found that the pro-inflammatory response depends on myeloid differentia

242 The initial post-MI pro-inflammatory response followed by reparative or anti

243 This was associated with an increased pro-inflammatory response in endothelial cells and the s

244 encephalomyocarditis virus (EMCV), induce a pro-inflammatory response in islets leading to local pro

245 bae natural host, and the paradoxical hMDMs' pro-inflammatory response is likely an evolutionary acci

246 tor 4 (TLR4) on macrophages induces a robust pro-inflammatory response that is dependent on metabolic

247 vefish immune cells display a more sensitive pro-inflammatory response towards bacterial endotoxins.

248 induction of the acute arterial WSS-induced pro-inflammatory response.

249 cytokines that categorically incite a robust pro-inflammatory response.

250 es nuclear NF-kappaB DNA-binding and thereby pro-inflammatory responses in monocytes and dendritic ce

251 ing virus replication and in suppressing the pro-inflammatory responses of human pathogenic viruses,

252 Ucp2(DeltaLysM) macrophages show attenuated pro-inflammatory responses toward Toll-like receptor-2 a

253 show that NFAT5, an activator of macrophage pro-inflammatory responses, represses Toll-like receptor

254 cell lysozyme balances intestinal anti- and pro-inflammatory responses, with implications for IBD.

255 of ALS as a disorder with extensive systemic pro-inflammatory responses.

256 m SFA-induced ectopic lipid accumulation and pro-inflammatory responses.

257 zyme-intact hosts, processed R. gnavus drove pro-inflammatory responses.

258 , inhibiting MAPK14 expression and impairing pro-inflammatory responses.

259 We confirmed a new pro-inflammatory role of Apelin in AS mice and in cultur

260 Next to the recently discovered pro-inflammatory role of cytosolic LPS, our data reveal

261 articularly, those mechanisms related to the pro-inflammatory role of neutrophils and the anti-inflam

262 nstrating cell survival following MOMP, this pro-inflammatory role suggests that mitochondria-derived

263 Besides pro-inflammatory roles, the ancient cytokine interleukin

264 tly, Pf reduced chemotaxis and production of pro-inflammatory ROS, cytokines, and chemokines by LPS-a

265 lammation-resolution and the accumulation of pro-inflammatory senescent cells (SCs).

266 The formation of tumors is dependent on a pro-inflammatory signaling cascade, which begins with th

267 activated genes (SAGs) included established pro-inflammatory signaling components known to act at mu

268 OXL2 is an anabolic effector that attenuates pro-inflammatory signaling in OA cartilage of the TMJ an

269 Early pro-inflammatory signaling in the endocrine pancreas inv

270 Gene expression of pro-inflammatory signaling pathways is increased and gen

271 neuroprotective strategy in PD that disrupts pro-inflammatory signaling, but maintains the beneficial

272 translocated effector proteins that inhibit pro-inflammatory signaling.

273 ing caspase activation, MOMP engages various pro-inflammatory signalling functions.

274 -kB dependent mechanism; and (b) exposure to pro-inflammatory signals such as IL1beta.

275 ught to arise, in part, because of a chronic pro-inflammatory state in the brain.

276 ammatory-prone UC patients, which promotes a pro-inflammatory state within the intestine that may be

277 netic risk factor for AD and is related to a pro-inflammatory state.

278 ategies that shift immune cell metabolism to pro-inflammatory states in the TME and highlight a need

279 y genes Il1b and Nos2, leading to a moderate pro-inflammatory status.

280 LPS-induced pro-inflammatory stimulation suppressed Trem2 expression

281 ve distinct cytokine profiles in response to pro-inflammatory stimuli derived from host and microbial

282 t high glucose in EV-targeted cells triggers pro-inflammatory stimuli via mTOR activation.

283 cilitated robust human cytokine responses to pro-inflammatory stimuli.

284 ited following exposure to host or microbial pro-inflammatory stimuli.

285 capacity to subsequently respond to a strong pro-inflammatory stimulus such as bacterial lipopolysacc

286 ociated with absolute abundance of CXCL10, a pro-inflammatory T-cell chemokine.

287 CHIKV pathogenesis, with a specific focus on pro-inflammatory Th1 responses in the development of CHI

288 w that SAAs additionally direct a pathogenic pro-inflammatory Th17 cell differentiation program, acti

289 the gut microbiota linked to a reduction in pro-inflammatory Th17 cells.

290 microbiota reduces the levels of intestinal pro-inflammatory Th17 cells.

291 Pro-inflammatory (TNF-alpha, IL-6) and pro-fibrotic (TGF

292 microglia/macrophages and the switch from a pro-inflammatory to an anti-inflammatory lesion environm

293 NF-kappaB is a pro-inflammatory transcription factor that critically re

294 ves the expression of MAFG and MAT2alpha and pro-inflammatory transcriptional modules, contributing t

295 odels, CAR-Ms were further shown to induce a pro-inflammatory tumor microenvironment and boost anti-t

296 ated gene signatures, elevated expression of pro-inflammatory tumorigenic cytokines, such as IL-17A a

297 e characterized by an exaggerated release of pro-inflammatory type 1 and type 3 cytokines.

298 However, pre-existing vector immunity and a pro-inflammatory vaccine adjuvant may influence RhCMV/SI

299 on 3 (STAT3) and subsequent induction of the pro-inflammatory vascular cell adhesion molecule 1 (VCAM

300 ytotoxic and they do not activate cells in a pro-inflammatory way.