ライフサイエンスコーパス: probiotic

1 t /placebo, and 27 receiving low FODMAP diet/probiotic).

2 biotic groups received Lactobacillus reuteri probiotic.

3 cosae, 1 L. vaginalis and the L. acidophilus probiotic.

4 HR (0.006, p < 0.0001) were in favour of the probiotic.

5 mediating the health-promoting attributes of probiotics.

6 o candidates to become industrially valuable probiotics.

7 were adjusted for gestational age and use of probiotics.

8 nutritional supplements with prebiotics and probiotics.

9 f H(2)O(2), D-lactate and L-lactate than the probiotics.

10 mmatory agents, antibacterial compounds, and probiotics.

11 nomes of many taxa found in over-the-counter probiotics.

12 ished reviews reporting favorable effects of probiotics.

13 irable starter cultures and health-promoting probiotics.

14 microbiome and a brief review of the use of probiotics.

15 w, most research has focused on lactobacilli probiotics.

16 ifying strategies, and engineered phages and probiotics.

17 ng sham diet/placebo, 26 receiving sham diet/probiotic, 24 receiving low FODMAP diet /placebo, and 27

18 old) with BMI 25-34.9 kg/m(2) received Lab4P probiotic (50 billion/day) or a matched placebo for 6 mo

19 operationally referred to as next-generation probiotics, a concept that overlaps with the emerging co

20 The role of plasmids in the probiotic activities of L. pentosus MP-10 was investigat

21 ts of herbs (such as cannabis and curcumin), probiotics, acupuncture, exercise, and mind-body therapy

22 dicated up to 2.5 times higher survival with probiotic addition, as well as 20% higher survival 7 day

23 onclude that our data do not support routine probiotic administration to children with acute gastroen

24 Probiotics administration was implemented in three nursi

25 f beneficial commensal microbes, marketed as probiotics, affects the enteric nervous system (ENS).

26 colonization by VRE and represent potential probiotic agents to re-establish resistance to VRE.

27 ct on postoperative infections compared with probiotics alone (synbiotics RR: 0.46; 95% CI: 0.33-0.66

28 n), anti-inflammatory drugs (mesalazine) and probiotics, alone or in combination, and eventually surg

29 icantly greater than that in the placebo and probiotics-alone groups (-0.59[-0.75, -0.44]%, -0.53[-0.

30 eatment of either BBR-alone, probiotics+BBR, probiotics-alone, or placebo, after a one-week run-in of

31 Synbiotics but not probiotics also led to a reduction in total length of st

32 ciated to health benefits because of being a probiotic and due to the presence of molecules with biol

33 o difference in eczema incidence between the probiotic and placebo groups (35[30%] of 118 infants vs

34 vs 13[11%] of 123) were similar between the probiotic and placebo groups.

35 administration of a synbiotic combination of probiotic and prebiotic agents affected liver fat conten

36 f administration of a synbiotic combination (probiotic and prebiotic) altered the fecal microbiome bu

37 t strongly affected by the co-culture of the probiotic and sprouts.

38 We studied the effects of the widely used probiotic and the commensal Lactobacillus rhamnosus GG (

39 252 participants) were included; 9 evaluated probiotics and 12 evaluated synbiotics, with treatment d

40 episodes that included supplementation with probiotics and 83 episodes with no probiotics supplement

41 te the microbiome (for example, antibiotics, probiotics and microbiota transplants) have been shown t

42 elopment of microbiome-related therapeutics, probiotics and nutraceuticals.

43 The combination of probiotics and prebiotics might be useful to treat oral

44 s, and synbiotics (preparations that combine probiotics and prebiotics) are nutritional adjuncts that

45 or implementation were perceived benefits of probiotics and prescription by medical staff.

46 light potential context-dependent effects of probiotics and suggest a model in which changes in host

47 Probiotics and synbiotics are safe and effective nutriti

48 py and cognitive behavioural therapy), diet (probiotics) and percutaneous electrical nerve field stim

49 onoprazan for proton pump inhibitors, adding probiotics, and vaccine development.

50 Pharmacologic and probiotic approaches directed towards specific TLR2 sign

51 Probiotics are a promising strategy as evidenced by bene

52 Evidence that probiotics are effective for prevention of allergic dise

53 Probiotics are frequently used by residents in care home

54 Probiotics are living microorganisms that are increasing

55 However, probiotics are not routinely used in Dutch nursing homes

56 Probiotics are routinely administered to hospitalized pa

57 lth-promoting effector molecules produced by probiotics are well documented and have been linked to s

58 nt evidence thus does not support the use of probiotics as a single or coadjuvant therapy for treatme

59 2 were observed in CRC patients who received probiotics as compared to pre-treatment level (P < 0.05)

60 The notion of probiotics as microbes that confer health benefits has i

61 ed a suitable approach for implementation of probiotics, as well as for evaluation of its effectivene

62 nd enzyme-inhibiting properties of potential probiotic Bacillus strains isolated from fermented brine

63 Exopolysaccharide (EPS) from the probiotic Bacillus subtilis reduces bacterial burden and

64 ly identified exopolysaccharide (EPS) from a probiotic, Bacillus subtilis, that induces anti-inflamma

65 eptidase activity was required for enhancing probiotic bacteria activity against Clostridium difficil

66 Probiotic bacteria are generally regarded as safe to con

67 creasing interest in targeted application of probiotic bacteria for prevention and treatment of airwa

68 Oral treatment with probiotic bacteria has been shown to prevent bone loss i

69 o-microcapsules of omega-3 rich tuna oil and probiotic bacteria L. casei were produced using whey pro

70 Cynara cardunculus enzymes and fermented by probiotic bacteria or unfermented beverage.

71 Probiotic bacteria reduce the intestinal colonization of

72 ts with prebiotic activity toward well-known probiotic bacteria, such as Lactobacillus acidophilus an

73 ul for finding disease-related pathogenic or probiotic bacteria.

74 ic functions could facilitate development of probiotic bacterial consortia that drive and/or restore

75 (exopolysaccharide-C47 product), a potential probiotic bacterium, on milk extracted from camels and 2

76 We tested the efficacy of a probiotic bacterium, Pseudomonas fluorescens, to reduce

77 h knowledge provides a foundation for future probiotics-based research in microbial organism mediated

78 Probiotic baths of surface symbionts, Pseudomonas fluore

79 haemoglobin, as the primary outcome, in the probiotics+BBR (least-squares mean [95% CI], -1.04[-1.19

80 ted a 12-week treatment of either BBR-alone, probiotics+BBR, probiotics-alone, or placebo, after a on

81 antibiotic-treated mice with a Lactobacillus probiotic before MI restored myeloid cell proportions, y

82 ied Potential probiotic benefits include accelerated gastrointestinal

83 Kefir, a probiotic beverage prepared from fermented milk, has bee

84 hereas Russian infants commonly maintained a probiotic Bifidobacterium bifidum strain in infancy.

85 Here, we bioengineered Lactobacillus probiotics (BLP) to express the Listeria adhesion protei

86 We explore the potential benefits of this probiotic by measuring inhibition of the periodontal pat

87 ntial wall material for targeted delivery of probiotics by altering its digestion.

88 adzuki and soybean sprouts enriched with the probiotic (by about 5% and 7% respectively).

89 Research shows that probiotics can be effective and safe in reducing AAD.

90 Unlike abiotic therapeutics, probiotics can replicate in their intended site, subject

91 Probiotic carriers (beads) were made by electrostatic ex

92 ithm for the rational design of personalized probiotic cocktails to decolonize pathogens.

93 ized to receive a daily capsule containing a probiotic combination of Lactobacillus rhamnosus GG and

94 nts in the United Kingdom, a daily dose of a probiotic combination of Lactobacillus rhamnosus GG and

95 We evaluated the effect of a postnatal probiotic combination on development of allergic disease

96 d no effect of postnatal administration of a probiotic combination on the incidence of allergic disea

97 mized 1099 very preterm infants to receive a probiotic combination or placebo from soon after birth u

98 nd other animals, and they can serve diverse probiotic, commensal and pathogenic roles in the host(2-

99 ensive care unit (ICU) patients treated with probiotics compared to those not treated, and provide ge

100 ta to enable meta-analysis of the effects of probiotics compared with control on defecation frequency

101 d trials (RCTs) that assessed the effects of probiotics compared with placebo or treatment as usual o

102 fat diet, 2-weeks supplementation with Lab4 probiotic consortium plus Lactobacillus plantarum CUL66

103 Our study aimed to determine the effect of probiotic consumption containing six viable microorganis

104 Murta enriched with probiotics contained higher L. casei viable counts after

105 Participants were randomized to receive a probiotic containing Lactobacillus rhamnosus and Lactoba

106 We have shown that probiotics containing six viable microorganisms of Lacto

107 e than one log CFU/g when compared to the no-probiotic control group.

108 s supplemented to the water only, and (3) no probiotic controls.

109 The addition of probiotic culture resulted in products with lower hardne

110 ed that WPH builds more suitable carrier for probiotic culture than WPC.

111 and the supplementation of Prato cheese with probiotic cultures may be an effective alternative to th

112 The microencapsulation of the probiotic cultures resulted in higher probiotic survival

113 ; and (5) role of alternative therapies like probiotics, curcumin, and fecal microbiota transplantati

114 Successful implementation of probiotics demonstrated the prevention of AAD in nursing

115 The use of next-generation probiotics derived from the intestinal microbiota repres

116 hat were free of high risk of bias (only 5), probiotics did not confer any beneficial effects on defe

117 When compared to (any) control intervention, probiotics did not significantly increase defecation fre

118 Future research should focus on optimal probiotic dose, species, and formulation.

119 n colonization with a commensal, potentially probiotic E. coli bacteriuria strain.

120 Combining spore-forming bacteria with a probiotic E. coli isolate protects germ-free mice from p

121 We exposed the candidate probiotic E. coli Nissle (EcN) to the mouse gastrointest

122 dimensional organization of a biofilm of the probiotic E. coli Nissle 1917 at 15 mum pixel size was o

123 cific beneficial effects attributable to the probiotic, either in reducing clinical symptoms or viral

124 Probiotic encapsulated in protein-alginate beads survive

125 ns (SGIC) is the most critical parameter for probiotic encapsulation.

126 (WPC) and whey protein hydrolysate (WPH) for probiotic encapsulation.

127 ant species L. crispatus, with potential for probiotic enhancement, biotherapeutic engineering, and m

128 Probiotics, enriched with these bacterial communities, a

129 e could be modelled by inoculating mice with probiotic Escherichia coli, which conferred resistance b

130 e been learned from working with traditional probiotics, explore the kinds of organisms that are like

131 tions, but most physicians also prescribed a probiotic for therapy.

132 e was no evidence for significant effects of probiotics for any of the study's endpoints on those com

133 s consuming different types of formula (pre-/probiotics for Cluster 3 [17%], pHF-HA for Cluster 4 [7%

134 therefore do not support the routine use of probiotics for improving growth or preventing late-onset

135 Clinical use of probiotics for LOS prophylaxis has varied owing to limit

136 czema; however, no studies have investigated probiotics for prevention of allergic diseases in very p

137 sm in the gut and thereby serve as potential probiotics for the management of androgen-dependent dise

138 4 weeks, along with a placebo or multistrain probiotic formulation, resulting in 4 groups (27 receivi

139 the effects of single-strain and multistrain probiotic formulations on outcomes of preterm, low-birth

140 for studies of single-strain and multistrain probiotic formulations on the outcomes of preterm, low-b

141 83 adverse events (150 adverse events in the probiotic group and 133 in the placebo group).

142 deaths accounted for 33 of the events in the probiotic group and 32 of the events in the placebo grou

143 alizations accounted for 94 of the events in probiotic group and 78 events in the placebo group, and

144 ) were available for 98.7% randomized to the probiotic group and 97.4% randomized to placebo.

145 results for all parameters were seen in the probiotic group compared with the control group (P <0.00

146 Care home residents randomized to the probiotic group had a mean of 12.9 cumulative systemic a

147 RTI (0.60, p < 0.0001) were recorded for the probiotic group.

148 Research into the benefits of probiotics has progressed beyond interventional studies

149 Probiotics have become one of effective alternatives to

150 Although probiotics have been touted as having the potential to e

151 IGNIFICANCE STATEMENT Commercially available probiotics have the potential to modify visceral pain.

152 etary exposures, provisions of prebiotics or probiotics have yet to show therapeutic benefit for CVD.

153 Greatest weight losses were among probiotic hypercholesterolaemic participants (-2.5%, p <

154 ucted to assess facilitators and barriers of probiotics implementation.

155 effectiveness of single- vs multiple-strain probiotics in a network meta-analysis of randomized tria

156 nd to evaluate the implementation process of probiotics in daily care.

157 There is growing interest in the use of probiotics in periodontal therapy; however, until now, m

158 tics, rigorous evidence assessing the use of probiotics in routine preterm newborn care is lacking.

159 reviews and meta-analyses on the efficacy of probiotics in the treatment of functional constipation i

160 These findings do not support the use of probiotics in this setting.

161 se developments have provided a boost to the probiotics industry, which continues to experience expon

162 Reported challenges were probiotics intake by residents and individual decision-m

163 erve to aid development of pharmacologic and probiotic intervention strategies to limit S. aureus ski

164 link between blood isolates and administered probiotics is lacking.

165 reatment of moderately preterm newborns with probiotics is unlikely to improve anthropometric outcome

166 The use of probiotics is widely extended in the case of gastrointes

167 ce ingestion of bacterial preparation (e.g., probiotics) is reported to impact human health, it is li

168 Combinations of probiotic L. fermentum and QUE and/or RES should be an i

169 The consumption of probiotic L. reuteri-lozenges is an efficacious measure

170 from South African women, commercial vaginal probiotics (L. casei rhamnosus, L. acidophilus) and 4 re

171 Probiotic lactic acid bacteria (LAB) are generally emplo

172 onstrated that the S-layer glycoprotein from probiotic Lactobacillus kefiri CIDCA 8348 (SLP-8348) is

173 testinal epithelial integrity, we introduced probiotic Lactobacillus plantarum into Simian immunodefi

174 f extracellular vesicles (EVs) isolated from probiotic Lactobacillus plantarum to protect tuna fish a

175 their own natural commensals (including the probiotic Lactobacillus plantarum).

176 Colonization of the gut by certain probiotic Lactobacillus reuteri strains has been associa

177 rolyzed casein formula (EHCF) containing the probiotic Lactobacillus rhamnosus GG (LGG) can reduce th

178 antibiotic administration or feeding with a probiotic Lactobacillus strain partially rescues the beh

179 ects of preventive intranasal treatment with probiotics Lactobacillus rhamnosus GG and L. rhamnosus G

180 and root planing (SRP) with/without adjunct probiotic (Lactobacillus reuteri) treatment towards the

181 eutical formulations composed of potentially probiotic Limosilactobacillus fermentum (L. fermentum 13

182 emented, other promising strategies, such as probiotics, lysins, and antimicrobial peptides, are in v

183 Probiotic may modify intestinal microenvironment resulti

184 Probiotics may improve quality of life during allergy se

185 evaluate whether the regular consumption of probiotics may improve the known deterioration of period

186 Probiotics may improve treatment outcomes, although subs

187 Apart from stimulating the growth of probiotic microflora, MOS impart anticancer and immunomo

188 ion process by drugs, nutrients, and pre- or probiotics might offer better therapeutic approaches.

189 nutrients and to rationally design effective probiotic mixtures.

190 (B. licheniformis and B. amyloliquefaciens) probiotic on rearing of larval common snook (Centropomus

191 ry, the mechanisms underlying the effects of probiotics on aging have rarely been assessed.

192 In this study, the effect of sustainable probiotics on Campylobacter jejuni colonization and gut

193 altering gut microbiota like oral intake of probiotics or berberine (BBR), a bacteriostatic agent, m

194 Modulation of the microbiome via probiotics or microbiota transplant might prove useful i

195 distributions and (iii) finding of potential probiotics or reliable pathogenic bacterial strains.

196 tify randomized controlled trials evaluating probiotics or synbiotics in adult patients undergoing el

197 Perioperative administration of either probiotics or synbiotics significantly reduced the risk

198 l could aid in the development of prebiotic, probiotic, or synthetic therapeutics that decrease the r

199 evidence that the same regulation occurs in probiotic organisms.

200 consumption of infant formula (regular, pre-/probiotics, partially hydrolysed with hypoallergenic lab

201 rval stocking to improve rearing success and probiotic performance.

202 cent work from Eran and colleagues shows how probiotics perturb rather than aid the recovery of the m

203 reuteri (ATTC PTA 5289) (test n = 36) or no probiotics (placebo n = 36).

204 ea bass, we have obtained isolates with high probiotic potential.

205 otective blends for manufacture of L. lactis probiotic powders was optimized using a statistical expe

206 Probiotics, prebiotics, and synbiotics (preparations tha

207 sed diets, and nutraceuticals, which include probiotics, prebiotics, and synbiotics.

208 microbiome-modulating interventions, such as probiotics, prebiotics, antibiotics, fecal microbiota tr

209 We discuss how probiotics, prebiotics, synbiotic, fecal microbiota tran

210 sing care), although the evidence on whether probiotics prevent infections and reduce antibiotic use

211 No probiotic product has been able to satisfy the regulator

212 om Lactobacilli isolated from the associated probiotic product.

213 -existing genetic heterogeneity found in the probiotic product.

214 charged with rigorous evaluation of specific probiotic products and the evidence in support of their

215 However, patients take probiotic products in the belief that they will help to

216 ld provide evidence for clinical efficacy of probiotic products.

217 during olive fermentation and enhance their probiotic properties and their competitiveness in severa

218 nisms were characterized based on additional probiotic properties and were evaluated for nutritional

219 In order to assess the essential probiotic properties of a strain dedicated for administr

220 activation patterns that indicate that this probiotic reduces limbic reactivity.

221 Six months supplementation with Lab4P probiotic resulted in significant weight reduction and i

222 Most importantly, the control and probiotic-rich sprouts retained high quality after cold

223 te ongoing debate about the health impact of probiotics, rigorous evidence assessing the use of probi

224 0 to -1.18 days; P = 0.005, n = 535, I = 91% probiotics RR: -0.65; 95% CI: -2.03-0.72; P = 0.35, n =

225 CI: 0.33-0.66; P < 0.0001, n = 1399, I = 53% probiotics RR: 0.65; 95% CI: 0.53-0.80; P < 0.0001, n =

226 utritional interventions with prebiotics and probiotics seem to exert immunological effects, their cl

227 Results suggest this probiotic should be tested in other marine fish species

228 n of yogurt, a standard yogurt culture and a probiotic strain Lactobacillus rhamnosus GG were used.

229 Engineering a probiotic strain with an adhesion protein from a non-pat

230 We evaluated the effect of a single probiotic strain, Saccharomyces boulardii, at a standard

231 de rennet is proposed as the novel source of probiotic strains as an alternative to the traditional c

232 Cheese is a suitable matrix to deliver probiotic strains but it contains a high amount of sodiu

233 It is particularly alarming that probiotic strains can cause bacteremia(8,9), yet direct

234 Our findings support that probiotic strains can directly cause bacteremia and adap

235 Hence, these probiotic strains have been showed to exhibit unique fun

236 the following 42 days containing either the probiotic strains Lactobacillus reuteri (DSM 17938 and L

237 Future UTI-preventive probiotic strains may benefit by retaining the escherich

238 ity) of camel milk fermented with indigenous probiotic strains of Lactobacillus spp., compared with f

239 ugh the development of salivaricin-producing probiotic strains.

240 own some promising results for prebiotic and probiotic strategies as prophylaxis or treatment of GVHD

241 inally, in a simple in vitro model, the oral probiotic strongly increased the secretion of the anti-i

242 ng the neonate's microbiome through maternal probiotic supplementation can improve offspring's neurod

243 ered randomized controlled trials evaluating probiotic supplementation for allergy prevention in very

244 This evidence suggests that maternal probiotic supplementation may be a safe and effective st

245 Probiotic supplementation to mothers and/or their term-b

246 monocytes, or dietary SCFA or Lactobacillus probiotic supplementation was conducted to evaluate the

247 Finally, probiotic supplementation with Lactobacillus reuteri did

248 ime and in response to interventions such as probiotic supplementation, antibiotic treatment or episo

249 in a randomized placebo-controlled study of probiotic supplementation.

250 hospital guidelines that recommended routine probiotics supplementation for neonates born before 34 c

251 med to estimate the causal effect of routine probiotics supplementation on moderately preterm newborn

252 did not change significantly as a result of probiotics supplementation.

253 tion with probiotics and 83 episodes with no probiotics supplementation.

254 Experimental treatments included (1) probiotics supplemented to the water and live feed, (2)

255 supplemented to the water and live feed, (2) probiotics supplemented to the water only, and (3) no pr

256 and feed utilization efficiency in fish fed probiotic-supplemented plant-based diets, thus contribut

257 of the probiotic cultures resulted in higher probiotic survival (>6 log CFU/mL in product and simulat

258 conclusion, microencapsulation improved the probiotic survival and the quality parameters of spreada

259 Significant changes in probiotic survival were observed; however, the sodium re

260 target the microbiota, including prebiotics, probiotics, synbiotics and faecal microbiota transplanta

261 MTT was defined as antibiotics, probiotics, synbiotics, or fecal microbiota transplantat

262 ed RCTs are needed to define the efficacy of probiotics/synbiotics for treatment of NAFLD.

263 The use of probiotics/synbiotics was associated with improvement in

264 Probiotics/synbiotics were also associated with increase

265 Probiotics/synbiotics were associated with a significant

266 of microbial species as pharmacological and probiotic targets in the context of inflammatory disease

267 Many probiotics that affect gut microbial ecology have been s

268 bacterial weapons can help in the design of probiotics that can both establish well and eliminate pr

269 Apart from probiotics that have already been tested in human random

270 nd provide a basis for rational selection of probiotics that modulate primary succession of the micro

271 rally Regarded as Safe and often employed as probiotics, the engineering of Lactobacillus membrane ve

272 a to better understand the mode of action of probiotics, their associated microbiomes, and their effe

273 the efficacy of SRP with and without adjunct probiotic therapy (PT) in the treatment of CP among sham

274 These results suggest that probiotic therapy during morphine administration may be

275 Integration of antibiotic and probiotic therapy has the potential to lessen the public

276 e composition and highlight the potential of probiotics to attenuate high-fat diet-related metabolic

277 izable pipeline that can be applied to other probiotics to better understand their safety and enginee

278 d prescribing prophylactic vancomycin and/or probiotics to colonized patients to prevent progression

279 evelop a procedure for the implementation of probiotics to prevent AAD in nursing homes, to evaluate

280 Long-term PPI users should not routinely use probiotics to prevent infection.

281 rt the idea of direct clonal transmission of probiotics to the bloodstream.

282 dition to human milk, such as prebiotics and probiotics, to the management of high-risk infants.

283 nation in mice is modulated by antibiotic or probiotic treatment, as well as in germ-free mice.

284 ium spp vs single- and other multiple-strain probiotic treatments.

285 onomic status, delivery mode, antibiotic and probiotic use, exposure to fermented and unpasteurized m

286 t asthma, although the results of studies of probiotics used together with prebiotics have been overa

287 is potential to develop an improved vaginal probiotic using clinical Lactobacillus isolates.

288 Probiotic viability in simulated gastrointestinal condit

289 The probiotic viable cells, the isoflavones profile and orga

290 The combination of probiotics, vitamins, and biological agents with AIT is

291 Lactobacilli-based vaginal probiotics warrant further evaluation because, in contra

292 Although the L. acidophilus probiotic was the most adherent, many clinical isolates

293 The probiotic was viable throughout storage in all fermented

294 A multispecies probiotics was administered twice daily upon start of an

295 The number of episodes with AAD when using probiotics was significantly lower than when no probioti

296 biotics was significantly lower than when no probiotics was used (20% vs 36%; p = 0,022, Chi-square).

297 ated Lactobacillus paracasei K5 (a potential probiotic) was immobilized on delignified wheat bran (DW

298 o evaluate the potential to improve existing probiotics, we compared the inflammatory and antimicrobi

299 Probiotics (WMD: -1.84; 95% CI: -3.30, -0.38; I2 = 23.6%

300 ce of effect for anthelmintics, antibiotics, probiotics, zinc, vitamin A, withholding breastfeeding,