ライフサイエンスコーパス: probiotics

1 mmatory agents, antibacterial compounds, and probiotics.

2 nomes of many taxa found in over-the-counter probiotics.

3 ished reviews reporting favorable effects of probiotics.

4 irable starter cultures and health-promoting probiotics.

5 microbiome and a brief review of the use of probiotics.

6 w, most research has focused on lactobacilli probiotics.

7 risk for adverse events among patients given probiotics.

8 e against this pathogen, represent potential probiotics.

9 Lactic acid bacteria (LAB) are the common probiotics.

10 phenols, carotenoids, vitamins, enzymes, and probiotics.

11 delivery carrier for oral administration of probiotics.

12 at-killed LAB may be developed as anti-virus probiotics.

13 nfections related to lactobacilli containing probiotics.

14 ential application for improving efficacy of probiotics.

15 ion in animals, targeted antibiotics, and/or probiotics.

16 ifying strategies, and engineered phages and probiotics.

17 management strategies, including the use of probiotics.

18 ce and severity of adverse events related to probiotics.

19 can be reversed by favorable alterations by probiotics.

20 trategies for their prevention is the use of probiotics.

21 en systems, which include bioremediation and probiotics.

22 olated from each patient originated from the probiotics.

23 n a variety of commercial products including probiotics.

24 es infantis bacteremia in newborns receiving probiotics.

25 mediating the health-promoting attributes of probiotics.

26 o candidates to become industrially valuable probiotics.

27 were adjusted for gestational age and use of probiotics.

28 nutritional supplements with prebiotics and probiotics.

29 f H(2)O(2), D-lactate and L-lactate than the probiotics.

30 operationally referred to as next-generation probiotics, a concept that overlaps with the emerging co

31 dobacterium genus, which is commonly used in probiotics, accumulated in the ankylosing spondylitis pa

32 ts of herbs (such as cannabis and curcumin), probiotics, acupuncture, exercise, and mind-body therapy

33 Probiotics administration was implemented in three nursi

34 f beneficial commensal microbes, marketed as probiotics, affects the enteric nervous system (ENS).

35 orted for probiotic encapsulation to protect probiotics against GI tract insults and improve their ad

36 creted to improve the protective activity of probiotics against Salmonella pathogenesis in C. elegans

37 nswers for presumed "fat drugs" and slimming probiotics alike.

38 ct on postoperative infections compared with probiotics alone (synbiotics RR: 0.46; 95% CI: 0.33-0.66

39 n), anti-inflammatory drugs (mesalazine) and probiotics, alone or in combination, and eventually surg

40 icantly greater than that in the placebo and probiotics-alone groups (-0.59[-0.75, -0.44]%, -0.53[-0.

41 eatment of either BBR-alone, probiotics+BBR, probiotics-alone, or placebo, after a one-week run-in of

42 Specific probiotics also have immunomodulatory and metabolic effe

43 Synbiotics but not probiotics also led to a reduction in total length of st

44 Studies have shown that probiotics alter gut flora and lead to elaboration of fl

45 252 participants) were included; 9 evaluated probiotics and 12 evaluated synbiotics, with treatment d

46 episodes that included supplementation with probiotics and 83 episodes with no probiotics supplement

47 Additionally, microbiota perturbations by probiotics and antibiotics exert modulatory effects on s

48 Treatment including antivirals, probiotics and antibiotics helps to improve the microbio

49 ndomized controlled trials evaluating use of probiotics and CDI in hospitalized adults taking antibio

50 These ternary blends protected the probiotics and enhanced their resistance to simulated ga

51 spite evidence for the beneficial effects of probiotics and low-fat dairy products, to our knowledge,

52 te the microbiome (for example, antibiotics, probiotics and microbiota transplants) have been shown t

53 elopment of microbiome-related therapeutics, probiotics and nutraceuticals.

54 Probiotics and omega-3 fatty acids may ameliorate diseas

55 ." We review some of the mechanisms by which probiotics and other beneficial commensals provide colon

56 The combination of probiotics and prebiotics might be useful to treat oral

57 finition of psychobiotics be expanded beyond probiotics and prebiotics to include other means of infl

58 administration of synbiotics (combination of probiotics and prebiotics) and must have included an ass

59 s, and synbiotics (preparations that combine probiotics and prebiotics) are nutritional adjuncts that

60 ed MEDLINE, EMBASE, International Journal of Probiotics and Prebiotics, and The Cochrane Library data

61 addressed in any safety assessment of novel probiotics and prebiotics.

62 or implementation were perceived benefits of probiotics and prescription by medical staff.

63 nt data suggest that the use of prophylactic probiotics and subglottic endotracheal tubes are cost-ef

64 light potential context-dependent effects of probiotics and suggest a model in which changes in host

65 Probiotics and synbiotics are safe and effective nutriti

66 , mucosal immunology, the health benefits of probiotics and the role of the microbiota during infecti

67 py and cognitive behavioural therapy), diet (probiotics) and percutaneous electrical nerve field stim

68 ological treatments, antidepressants, fiber, probiotics, and anticholinergics have not been adequatel

69 s of disease prevention, including vaccines, probiotics, and bacteriophages.

70 itions through administration of prebiotics, probiotics, and synbiotics.

71 luded subglottic suction endotracheal tubes, probiotics, and the Institute for Healthcare Improvement

72 onoprazan for proton pump inhibitors, adding probiotics, and vaccine development.

73 The most advanced approaches are antibodies, probiotics, and vaccines in phase 2 and phase 3 trials.

74 s, targeting of gut microbiota by innovative probiotics, antibiotics, and fecal transplant, in combin

75 Probiotics are a promising strategy as evidenced by bene

76 Probiotics are able to cause this effect within the body

77 ine: Moderate-quality evidence suggests that probiotics are associated with lower rates of antibiotic

78 addition, the uses or indications for these probiotics are described, along with the types of clinic

79 Evidence that probiotics are effective for prevention of allergic dise

80 Probiotics are extensively used to promote gastrointesti

81 Probiotics are frequently used by residents in care home

82 itro studies all support the assumption that probiotics are generally safe for most populations.

83 Probiotics are known to improve gut maturity and functio

84 Probiotics are living microorganisms that are increasing

85 Probiotics are living microorganisms that provide benefi

86 However, probiotics are not routinely used in Dutch nursing homes

87 Probiotics are routinely administered to hospitalized pa

88 lth-promoting effector molecules produced by probiotics are well documented and have been linked to s

89 nt evidence thus does not support the use of probiotics as a single or coadjuvant therapy for treatme

90 2 were observed in CRC patients who received probiotics as compared to pre-treatment level (P < 0.05)

91 The notion of probiotics as microbes that confer health benefits has i

92 and modulation of the gut microbiota (e.g., probiotics) as a potential treatment to decrease parasit

93 ed a suitable approach for implementation of probiotics, as well as for evaluation of its effectivene

94 h knowledge provides a foundation for future probiotics-based research in microbial organism mediated

95 haemoglobin, as the primary outcome, in the probiotics+BBR (least-squares mean [95% CI], -1.04[-1.19

96 ted a 12-week treatment of either BBR-alone, probiotics+BBR, probiotics-alone, or placebo, after a on

97 Here, we bioengineered Lactobacillus probiotics (BLP) to express the Listeria adhesion protei

98 ntial wall material for targeted delivery of probiotics by altering its digestion.

99 Research shows that probiotics can be effective and safe in reducing AAD.

100 Probiotics can modulate the immune system in healthy ind

101 BACKGROUND & AIMS: Probiotics can reduce symptoms of irritable bowel syndro

102 Unlike abiotic therapeutics, probiotics can replicate in their intended site, subject

103 is, we found evidence that administration of probiotics closer to the first dose of antibiotic reduce

104 ensive care unit (ICU) patients treated with probiotics compared to those not treated, and provide ge

105 ta to enable meta-analysis of the effects of probiotics compared with control on defecation frequency

106 d trials (RCTs) that assessed the effects of probiotics compared with placebo or treatment as usual o

107 Not only are probiotics considered beneficial to digestive health, bu

108 Murta enriched with probiotics contained higher L. casei viable counts after

109 nd bacteremia from lactobacillus after using probiotics containing lactobacilli in the course of her

110 fect is warranted with the increasing use of probiotics containing lactobacilli.

111 We have shown that probiotics containing six viable microorganisms of Lacto

112 nate respiration or treatment using targeted probiotics could prevent microbiota alterations and infl

113 Its enrichment with probiotics could thus further enhance its functional pro

114 cies and functions, for example, by pre- and probiotics, could enhance microbiome resilience and lead

115 ; and (5) role of alternative therapies like probiotics, curcumin, and fecal microbiota transplantati

116 The leading probiotics currently available to consumers are generall

117 ro treatment of mononuclear cells with these probiotics demonstrated that EcN, but not LGG, induced I

118 Successful implementation of probiotics demonstrated the prevention of AAD in nursing

119 The use of next-generation probiotics derived from the intestinal microbiota repres

120 hat were free of high risk of bias (only 5), probiotics did not confer any beneficial effects on defe

121 When compared to (any) control intervention, probiotics did not significantly increase defecation fre

122 However, how probiotics do this remains unclear.

123 ized controlled trials evaluating the use of probiotics during pregnancy or early infancy for prevent

124 Probiotics encapsulated with the ternary blends incorpor

125 Probiotics, enriched with these bacterial communities, a

126 ptoms, although the mechanisms through which probiotics exert their beneficial effects are largely un

127 e been learned from working with traditional probiotics, explore the kinds of organisms that are like

128 iometabolic effects of phenolics, dairy fat, probiotics, fermentation, coffee, tea, cocoa, eggs, spec

129 e was no evidence for significant effects of probiotics for any of the study's endpoints on those com

130 s consuming different types of formula (pre-/probiotics for Cluster 3 [17%], pHF-HA for Cluster 4 [7%

131 e balance of intestinal flora by introducing probiotics for disease prevention and treatment could be

132 therefore do not support the routine use of probiotics for improving growth or preventing late-onset

133 Clinical use of probiotics for LOS prophylaxis has varied owing to limit

134 czema; however, no studies have investigated probiotics for prevention of allergic diseases in very p

135 Their use as probiotics for prevention of Clostridium difficile infec

136 sm in the gut and thereby serve as potential probiotics for the management of androgen-dependent dise

137 tudy highlight the potential for repurposing probiotics for the therapy of osteoporosis.

138 for alternatives to pharmaceuticals, such as probiotics, for the prevention of allergic disease.

139 y of delay in starting probiotics (P = .04); probiotics given within 2 days of antibiotic initiation

140 (95% CI 0.68-1.27); 73 (11%) infants in the probiotics group had sepsis compared with 77 (12%) in th

141 -obesity group and lyophilized monocomponent probiotics groups (III-V).

142 roup II, MSG-obesity group) and treated with probiotics (groups III-VII).

143 Infants treated with probiotics had a significantly lower RR for eczema compa

144 The consumption of probiotics has become increasingly popular as a means to

145 Research into the benefits of probiotics has progressed beyond interventional studies

146 Probiotics have become one of effective alternatives to

147 Probiotics have been hypothesized to affect immunologic

148 Probiotics have been increasingly investigated in its ma

149 Given this scenario, probiotics have been suggested as a useful alternative f

150 Although probiotics have been touted as having the potential to e

151 Probiotics have been used safely for years.

152 Supplements such as probiotics have not proved helpful, but allergen-specifi

153 Probiotics have shown beneficial effects on health and p

154 IGNIFICANCE STATEMENT Commercially available probiotics have the potential to modify visceral pain.

155 etary exposures, provisions of prebiotics or probiotics have yet to show therapeutic benefit for CVD.

156 , easy answers (whether about antibiotics or probiotics) have again given way to an appreciation for

157 Live bacteria (such as probiotics) have long been used to modulate gut microbio

158 Synbiotics, a mixture of prebiotics and probiotics, have been used for the prevention and treatm

159 Developing genetically engineered probiotics holds great promise as a new therapeutic para

160 ucted to assess facilitators and barriers of probiotics implementation.

161 Probiotics improved stool consistency (SMD: +0.55; 95% C

162 effectiveness of single- vs multiple-strain probiotics in a network meta-analysis of randomized tria

163 alyzed the available data on the efficacy of probiotics in candidal colonization of host surfaces.

164 nd to evaluate the implementation process of probiotics in daily care.

165 quipped to answer questions on the safety of probiotics in intervention studies with confidence." Cri

166 There is growing interest in the use of probiotics in periodontal therapy; however, until now, m

167 s have provided evidence for the efficacy of probiotics in preventing Clostridium difficile infection

168 required to establish safety and efficacy of probiotics in reducing fracture risk in people.

169 ls have also shown the beneficial effects of probiotics in reducing oral, vaginal, and enteric coloni

170 tics, rigorous evidence assessing the use of probiotics in routine preterm newborn care is lacking.

171 The efficacy of probiotics in the context of atopic diseases has been we

172 ectious diseases and for stably establishing probiotics in the gut.

173 The growth of probiotics in the presence of total, acidic or neutral p

174 reviews and meta-analyses on the efficacy of probiotics in the treatment of functional constipation i

175 These findings do not support the use of probiotics in this setting.

176 idial gastroenteritis emphasizes the role of probiotics in treating intestinal impairment after infec

177 te to significantly enhanced survival of LbL-probiotics in vivo.

178 dies are required to assess the viability of probiotics in yogurts protected using MTGase-mediated mi

179 se developments have provided a boost to the probiotics industry, which continues to experience expon

180 Reported challenges were probiotics intake by residents and individual decision-m

181 where the rational design of next-generation probiotics is being actively pursued to prevent disease

182 link between blood isolates and administered probiotics is lacking.

183 known, but the role of Lactobacillus species probiotics is still controversial.

184 However, a concern for application of probiotics is the loss of viability during storage and g

185 reatment of moderately preterm newborns with probiotics is unlikely to improve anthropometric outcome

186 The use of probiotics is widely extended in the case of gastrointes

187 ce ingestion of bacterial preparation (e.g., probiotics) is reported to impact human health, it is li

188 from South African women, commercial vaginal probiotics (L. casei rhamnosus, L. acidophilus) and 4 re

189 Lactulose, probiotics, L-ornithine-L-aspartate, and potassium-iron-

190 tment of sex steroid-deficient mice with the probiotics Lactobacillus rhamnosus GG (LGG) or the comme

191 ects of preventive intranasal treatment with probiotics Lactobacillus rhamnosus GG and L. rhamnosus G

192 Two candidate probiotics, Lactococcus lactis NCC 2287 and Bifidobacter

193 emented, other promising strategies, such as probiotics, lysins, and antimicrobial peptides, are in v

194 se findings broaden our understanding of how probiotics may beneficially affect brain function in the

195 Probiotics may help improve natural immunity in patients

196 Probiotics may improve quality of life during allergy se

197 evaluate whether the regular consumption of probiotics may improve the known deterioration of period

198 Probiotics may improve treatment outcomes, although subs

199 Probiotics may improve whole gut transit time, stool fre

200 Probiotics may reduce necrotising enterocolitis and late

201 Probiotics may serve in the future as a worthy ally in t

202 ions highlight a novel pathway through which probiotics mediate cerebral changes and alter behavior.

203 ta modification with specific prebiotics and probiotics might offer a novel and cost-effective means

204 ion process by drugs, nutrients, and pre- or probiotics might offer better therapeutic approaches.

205 hat Lactobacillus fermentum, one of the main probiotics of the microbiota, exhibits an extraordinary

206 The study suggests that probiotics offer promise as a potential therapy for the

207 ry, the mechanisms underlying the effects of probiotics on aging have rarely been assessed.

208 In this study, the effect of sustainable probiotics on Campylobacter jejuni colonization and gut

209 We assessed the evidence on effects of probiotics on enteral nutrition in preterm neonates.

210 e is known about the impact of commonly used probiotics on human RV (HRV) infection.

211 altering gut microbiota like oral intake of probiotics or berberine (BBR), a bacteriostatic agent, m

212 Modulation of the microbiome via probiotics or microbiota transplant might prove useful i

213 distributions and (iii) finding of potential probiotics or reliable pathogenic bacterial strains.

214 tify randomized controlled trials evaluating probiotics or synbiotics in adult patients undergoing el

215 Perioperative administration of either probiotics or synbiotics significantly reduced the risk

216 either RCE (60 mg isoflavone aglycones/d and probiotics) or a masked placebo [control (CON)].RCE sign

217 efficacy for every day of delay in starting probiotics (P = .04); probiotics given within 2 days of

218 nsumed raw food (P = 0.01), to have consumed probiotics (P = 0.002), or to have been given antibiotic

219 consumption of infant formula (regular, pre-/probiotics, partially hydrolysed with hypoallergenic lab

220 ber of well-controlled studies indicate that probiotics, particularly lactobacilli, suppressCandidagr

221 strointestinal (GI) tract through the use of probiotics (PBio) is a safe and well-tolerated approach

222 cent work from Eran and colleagues shows how probiotics perturb rather than aid the recovery of the m

223 reuteri (ATTC PTA 5289) (test n = 36) or no probiotics (placebo n = 36).

224 Probiotics, prebiotics, and synbiotics (preparations tha

225 Recently, the effectiveness of probiotics, prebiotics, and synbiotics in reducing posto

226 sed diets, and nutraceuticals, which include probiotics, prebiotics, and synbiotics.

227 microbiome-modulating interventions, such as probiotics, prebiotics, antibiotics, fecal microbiota tr

228 formula with additional active ingredients (probiotics, prebiotics, or both) (LPFA) and breastfed in

229 We discuss how probiotics, prebiotics, synbiotic, fecal microbiota tran

230 lows for a more holistic approach when using probiotics, prebiotics, synbiotics, antibiotics, and ant

231 sing care), although the evidence on whether probiotics prevent infections and reduce antibiotic use

232 nonantibiotic prophylactic measures such as probiotics, prokinetics, bile acids, statins, and hemato

233 Although probiotics remain a promising option, there are challeng

234 Additionally and not unexpectedly, probiotics reversed hypogonadal osteopenia in sex steroi

235 te ongoing debate about the health impact of probiotics, rigorous evidence assessing the use of probi

236 0 to -1.18 days; P = 0.005, n = 535, I = 91% probiotics RR: -0.65; 95% CI: -2.03-0.72; P = 0.35, n =

237 CI: 0.33-0.66; P < 0.0001, n = 1399, I = 53% probiotics RR: 0.65; 95% CI: 0.53-0.80; P < 0.0001, n =

238 ecially those supplemented with a mixture of probiotics (RR 0.54 [95% CI: 0.43-0.68], P < 0.00001).

239 utritional interventions with prebiotics and probiotics seem to exert immunological effects, their cl

240 Prophylactic agents such as probiotics should be studied prospectively in patients w

241 hospital guidelines that recommended routine probiotics supplementation for neonates born before 34 c

242 med to estimate the causal effect of routine probiotics supplementation on moderately preterm newborn

243 tion with probiotics and 83 episodes with no probiotics supplementation.

244 did not change significantly as a result of probiotics supplementation.

245 Experimental treatments included (1) probiotics supplemented to the water and live feed, (2)

246 supplemented to the water and live feed, (2) probiotics supplemented to the water only, and (3) no pr

247 Microencapsulated probiotics survived well in simulated gastrointestinal c

248 target the microbiota, including prebiotics, probiotics, synbiotics and faecal microbiota transplanta

249 MTT was defined as antibiotics, probiotics, synbiotics, or fecal microbiota transplantat

250 ed RCTs are needed to define the efficacy of probiotics/synbiotics for treatment of NAFLD.

251 The use of probiotics/synbiotics was associated with improvement in

252 Probiotics/synbiotics were also associated with increase

253 Probiotics/synbiotics were associated with a significant

254 Many probiotics that affect gut microbial ecology have been s

255 bacterial weapons can help in the design of probiotics that can both establish well and eliminate pr

256 Our data further suggest that probiotics that decrease gut permeability have potential

257 Apart from probiotics that have already been tested in human random

258 nd provide a basis for rational selection of probiotics that modulate primary succession of the micro

259 rally Regarded as Safe and often employed as probiotics, the engineering of Lactobacillus membrane ve

260 a to better understand the mode of action of probiotics, their associated microbiomes, and their effe

261 nd suggests novel metabolic targets for pre-/probiotics therapies.

262 nto the mechanisms adopted by commensals and probiotics to adapt to the mucosal environment.

263 e composition and highlight the potential of probiotics to attenuate high-fat diet-related metabolic

264 izable pipeline that can be applied to other probiotics to better understand their safety and enginee

265 d prescribing prophylactic vancomycin and/or probiotics to colonized patients to prevent progression

266 tract (RCE) rich in isoflavone aglycones and probiotics to concomitantly promote uptake and a favorab

267 Administration of probiotics to premature newborns has been shown to preve

268 evelop a procedure for the implementation of probiotics to prevent AAD in nursing homes, to evaluate

269 n-pathogenic organisms and have been used as probiotics to prevent antibiotic associated diarrhea.

270 tors (variable); (3) utilization of specific probiotics to prevent C. difficile overgrowth (8/8); (4)

271 Long-term PPI users should not routinely use probiotics to prevent infection.

272 usses the literature available on the use of probiotics to prevent primary and secondary CDI.

273 is moderate evidence on the effectiveness of probiotics to prevent primary CDI, but there are few dat

274 f studies have investigated the potential of probiotics to promote wound healing in the digestive tra

275 The development of next-generation probiotics to reestablish colonization resistance and el

276 s that can be developed into next-generation probiotics to reestablish or enhance colonization resist

277 Our results indicate that development of probiotics to target multiple E. coli pathotypes will be

278 rt the idea of direct clonal transmission of probiotics to the bloodstream.

279 dition to human milk, such as prebiotics and probiotics, to the management of high-risk infants.

280 further studies before any recommendation of probiotics use is made.

281 t asthma, although the results of studies of probiotics used together with prebiotics have been overa

282 present work describes the encapsulation of probiotics using a by-product as wall material and a pro

283 and to clarify the relative contributions of probiotics versus OIT.

284 The combination of probiotics, vitamins, and biological agents with AIT is

285 Conversely, feeding SCI mice commercial probiotics (VSL#3) enriched with lactic acid-producing b

286 Lactobacilli-based vaginal probiotics warrant further evaluation because, in contra

287 A multispecies probiotics was administered twice daily upon start of an

288 The number of episodes with AAD when using probiotics was significantly lower than when no probioti

289 The treatment with probiotics was started at the age of 1 month.

290 biotics was significantly lower than when no probiotics was used (20% vs 36%; p = 0,022, Chi-square).

291 o evaluate the potential to improve existing probiotics, we compared the inflammatory and antimicrobi

292 adequate amounts and, as such, are labeled "probiotics." We review some of the mechanisms by which p

293 Meta-regression analysis demonstrated that probiotics were significantly more effective if given cl

294 ncapsulation system to preserve viability of probiotics when they are administrated orally and apply

295 This research shows that probiotics, when eaten, can improve the abnormal behavio

296 This review briefly describes the history of probiotics, where probiotic strains were originally isol

297 cs were previously defined as live bacteria (probiotics) which, when ingested, confer mental health b

298 The development of probiotics, which are living bacteria or yeasts used to

299 Probiotics (WMD: -1.84; 95% CI: -3.30, -0.38; I2 = 23.6%

300 ce of effect for anthelmintics, antibiotics, probiotics, zinc, vitamin A, withholding breastfeeding,