ライフサイエンスコーパス: prodrome

1 tions to slow or stop progression beyond the prodrome.

2 e of axonal injury in the multiple sclerosis prodrome.

3 the proportion of patients who experienced a prodrome.

4 tors must be re-evaluated in light of the MS prodrome.

5 who experienced this sleep disorder in their prodrome.

6 ), supporting the concept of an epileptic AD prodrome.

7 ent of migraine when administered during the prodrome.

8 eviously thought in the Huntington's disease prodrome.

9 nt of migraine attacks when taken during the prodrome.

10 n research protocols involving the psychosis prodrome.

11 ld be considered as potential markers of the prodrome.

12 toms, and 19% reported an initial infectious prodrome.

13 sures) and the absence of a distinct febrile prodrome.

14 no sensory disturbance after a mild flu-like prodrome.

15 ed over to be treated for 2 HAE attacks or 2 prodromes.

16 The duration of the UMD prodrome (18[36] months) was shorter than BMD (26[35], d

17 syncope was associated with the presence of prodromes (+23%, P < 0.001) and the diagnoses of VVS (+2

18 Prodromes (64 vs. 26%, P < 0.001) and vasovagal syncope

19 For predictive purposes, the prodrome - a constellation of symptoms which may occur b

20 e identification and intervention during the prodrome, a resolution of this question as well as a con

21 perkinetic encephalitis and neuropsychiatric prodrome admitted to the intensive care unit.

22 e major enriched pathways shared between HAE prodrome and attack were associated with neutrophil func

23 se from smoking onset during a schizophrenic prodrome and demonstrates a clear dose-response relation

24 research is needed to fully characterize the prodrome and develop standardized criteria to reliably i

25 etermine if recognition of this neurocardiac prodrome and earlier institution of immunosuppression ca

26 s who first applied penciclovir cream in the prodrome and erythema stages and among those who started

27 tratified by geographical region, infectious prodrome and GBS subtype.

28 symptoms, periods of untreated psychosis and prodrome and premorbid adjustment.

29 se diagnostic criteria for the schizophrenic prodrome and the Structured Interview for Prodromal Synd

30 aberrant cortical thinning in schizophrenia prodromes and reduced prefrontal cortical thickness in c

31 Attacks often begin with warning signs (prodromes) and aura (transient focal neurological sympto

32 , age 50 years and older, initial infectious prodrome, antidepressant use, and 4-hour gastric retenti

33 e duration and first presentation of the SMD prodromes as recorded in secondary mental health care.

34 Approximately 42% of prodrome-associated differentially expressed genes were

35 NF-alpha and IL-10 were 2 major hub genes in prodrome-associated enriched gene networks.

36 The CT group also coped better with manic prodromes at 12 months.

37 ere obtained (1) at baseline, (2) during the prodrome before and after treatment, and (3) during an a

38 sitive patients presented with a psychiatric prodrome, before developing seizures and obtundation req

39 ventions within the autism spectrum disorder prodrome, but available evidence relates to children at

40 Knowledge of the MS prodrome could also affect research into the causes of M

41 A better understanding of the MS prodrome could have profound clinical implications as it

42 Inclusion criteria included a consistent prodrome definition and reporting the proportion of pati

43 ed significantly in terms of methodology and prodrome definition used.

44 ul differences in prevalence between grouped prodrome definitions, and subgroup analyses failed to re

45 developing AD, suggesting that rather than a prodrome, depression may be a risk factor for AD.

46 he enriched gene networks with hub genes for prodrome (ERK and VEGF) and for acute attack (insulin an

47 ogepant 100 mg to treat the first qualifying prodrome event and placebo to treat the second qualifyin

48 eceive placebo to treat the first qualifying prodrome event and ubrogepant 100 mg to treat the second

49 gepant 100 mg to treat the second qualifying prodrome event or to receive ubrogepant 100 mg to treat

50 e study drug at the onset of each qualifying prodrome event.

51 t and placebo to treat the second qualifying prodrome event.

52 gepant and after 121 (29%) of 423 qualifying prodrome events that had been treated with placebo (odds

53 e occurred after 190 (46%) of 418 qualifying prodrome events that had been treated with ubrogepant an

54 re reported after 77 (17%) of 456 qualifying prodrome events that had been treated with ubrogepant an

55 dysfunction, neuropsychiatric changes, viral prodrome, faciobrachial dystonic spells or facial dyskin

56 reating mild cognitive impairment (MCI) as a prodrome for AD has also had very limited success.

57 patterns were observed, one with a prolonged prodrome (>/=7 days), respiratory manifestations, an imm

58 s was reported in 3 (23.1%), and a prolonged prodrome (>1 week) occurred in 5 (38.5%).

59 ntervention for the autism spectrum disorder prodrome had no immediate treatment effect on early auti

60 future research to fully characterize the MS prodrome, identify early disease markers and develop sta

61 lammatory diseases, but the possibility of a prodrome in multiple sclerosis (MS) has received relativ

62 , outpatient programs studying the psychosis prodrome in North America.

63 rity of patients with psychosis experience a prodrome in some form, it is unclear if the remainder of

64 mmarize what is currently known about the MS prodrome, including its possible duration, clinical feat

65 s chronic disorder, and the possibility of a prodrome indicates a window of opportunity to potentiall

66 set of neurological prodromes, lack of other prodromes, initial nonshockable rhythm, and unspecific e

67 in a small minority (n = 3); the observable prodrome invariably involved the lower motor neuron axis

68 R=3.06, 1.84-5.11, p<0.0001) than diarrhoeal prodrome (IRR=1.10, 0.60-2.00, p=0.76) and a greater inc

69 greater seasonal variation with respiratory prodrome (IRR=3.06, 1.84-5.11, p<0.0001) than diarrhoeal

70 A prodrome is an early set of signs or symptoms that indic

71 A prodrome is an early set of signs, symptoms or other fin

72 ion as well as a consensus definition of the prodrome is much needed in order to effectively direct a

73 The prodrome is the earliest phase of a migraine attack and

74 s on the extent of axonal injury during this prodrome is unknown.

75 group, female gender, onset of neurological prodromes, lack of other prodromes, initial nonshockable

76 he CSF, and one with a brief (<7 days) or no prodrome, less frequent respiratory manifestations and I

77 In the North American Prodrome Longitudinal Studies 2 and 3, negative symptoms

78 d (N = 699) iterations of the North American Prodrome Longitudinal Study (NAPLS 2 and 3) were assesse

79 13 in the second phase of the North American Prodrome Longitudinal Study (NAPLS 2).

80 part of the third wave of the North American Prodrome Longitudinal Study (NAPLS 3), which is a 9-site

81 In a recent report of the North American Prodrome Longitudinal Study (NAPLS), clinical high-risk

82 of the multisite case-control North American Prodrome Longitudinal Study (NAPLS-2) from 8 university-

83 rt of the second phase of the North American Prodrome Longitudinal Study (NAPLS-2), Cannon and collea

84 HR individuals comprising the North American Prodrome Longitudinal Study (NAPLS-3).

85 ants in the third wave of the North American Prodrome Longitudinal Study (NAPLS3), this report invest

86 nd neuroimaging data from the North American Prodrome Longitudinal Study 2 (NAPLS2) was used for anal

87 nalyzed data from the NAPLS2 (North American Prodrome Longitudinal Study 2) (n = 345), a multisite pr

88 previously described NAPLS-2 (North American Prodrome Longitudinal Study 2) calculator in 334 patient

89 Data were collected from the North American Prodrome Longitudinal Study Phase 2.

90 from the second phase of the North American Prodrome Longitudinal Study who were followed up to the

91 individuals from the NAPLS2 (North American Prodrome Longitudinal Study) were used to evaluate SEMs

92 f the second and third NAPLS (North American Prodrome Longitudinal Study).

93 were collected as part of the North American Prodrome Longitudinal Study-2 (NAPLS 2) between November

94 46% female) from the NAPLS-2 (North American Prodrome Longitudinal Study-2).

95 ucted at eight centers in the North American Prodrome Longitudinal Study.

96 were collected as part of the North American Prodrome Longitudinal Study.

97 ve sex with men (MSM) currently, the febrile prodrome may be absent and skin/mucosal lesions may be i

98 70.1, s.d.+/-6.7, 55-87 years) with dementia prodrome mild cognitive impairment were recruited in the

99 general population) of both dementia and its prodrome, mild cognitive impairment (MCI), which are cha

100 id eye movement sleep behavior disorder is a prodrome of alpha-synucleinopathies.

101 ild cognitive impairment (MCI), a recognized prodrome of Alzheimer's disease, recall shows greater de

102 r moderate to severe depression to suggest a prodrome of an alpha-synucleinopathy, hypnopompic or hyp

103 xclude the possibility that depression was a prodrome of dementia, dementia diagnoses were only based

104 n has been identified as a risk factor and a prodrome of dementia.

105 During the prodrome of FBDS alone, patients had normal sodium and b

106 Timing is everything, as neither the prodrome of islet autoimmunity nor the clinical onset of

107 eep Behavior Disorder (iRBD) is considered a prodrome of Parkinson's disease (PD).

108 tential microbiome-dependent subtypes in the prodrome of PD need further investigation based on prosp

109 Participants in a study of the etiology and prodrome of PD were reevaluated in this clinic-based 2-y

110 tion in clinical markers consistent with the prodrome of PD.

111 welling, particularly over the hands, with a prodrome of pruritus and paresthesias.

112 ity (DSC) in schizophrenia and people in the prodrome of psychosis.

113 gate the molecular mechanisms underlying the prodrome of schizophrenia.

114 dity of a set of diagnostic criteria for the prodrome of the first episode of schizophrenic psychosis

115 A prodrome of thigh pain, lack of trauma prior to the frac

116 We describe a novel neurocardiac prodrome of VGKCc-Ab/LGI1-encephalitis.

117 ic bradycardia is a distinctive neurocardiac prodrome of VGKCc/LGI1-Ab encephalitis.

118 and massive edema, often after a nonspecific prodrome of weakness, fatigue, and myalgias, and are at

119 le paraplegia, these patients presented with prodromes of fever and urinary retention, but were misdi

120 ecognition of fever and urinary retention as prodromes of irreversible paraplegia may allow earlier d

121 ting the progression of residual symptoms to prodromes of relapse.

122 BD) is one of the earliest and most specific prodromes of the alpha-synucleinopathies including Parki

123 All patients were treated during the prodrome or acute attack with rhC1-INH; (conestat alfa,

124 infectious while incubating or during their prodrome or acute illness.

125 mly assigned 5 HAE-C1-INH type 1 patients to prodrome or attack treatment groups; after a patient was

126 s apparent when therapy was initiated early (prodrome or erythema lesion stage) and when initiated la

127 ear what proportion of patients experience a prodrome or how this varies based on the multiple defini

128 ted AML [t-AML]), or without an identifiable prodrome or known exposure (de novo AML).

129 We excluded studies of only patients with a prodrome or solely substance-induced psychosis, qualitat

130 APMPPE may be preceded by a viral prodrome or vaccination, both of which were seen in this

131 ps; after a patient was treated for either 2 prodromes or 2 HAE attacks, they were crossed over to be

132 r if the remainder of patients experience no prodrome, or if ascertainment methods employed in the st

133 m may play an important role in the early or prodrome phase of disease as well as serving as a source

134 The most frequently reported prodrome phase symptoms were nausea (n = 12, 92.3%), anx

135 ffects proportion meta-analysis estimate for prodrome prevalence was 78.3% (95% CI = 72.8-83.2); hete

136 oportion meta-analysis were used to estimate prodrome prevalence.

137 nts (78.3%) were found to have experienced a prodrome prior to psychosis onset.

138 the proportion of patients who experienced a prodrome prior to psychosis onset.

139 e first meta-analysis on the prevalence of a prodrome prior to the onset of first episode psychosis.

140 Studying a prodrome requires techniques other than clinical observa

141 disorder might be better conceptualized as a prodrome, residual, or severity marker of major depressi

142 al MRI studies in patients, including in the prodrome, show divergent trajectories in grey matter vol

143 ribed here more faithfully recapitulates the prodrome that has been reported for human EVD.

144 -INH type 1 patients who have a well-defined prodrome that historically results in an acute attack ma

145 ork has identified the presence of a bipolar prodrome, the predictive implications for the individual

146 il symptom onset, and increased 10-fold from prodrome to acute illness.

147 are seen as a canonical sign of aging and a prodrome to dementia in older adults.

148 iety and behavioural changes can represent a prodrome to neurodegeneration; empirical data are requir

149 This PRODROME trial was a phase 3, multicentre, randomised, d

150 mbinant human C1-INH (rhC1-INH) during their prodrome versus an active swelling episode and associate

151 In patients with early-onset syncope, prodromes, VVS, and complex syncope are more common.

152 PRODROME was a phase 3, placebo-controlled, double-blind

153 presentation, and transdiagnosticity of the prodrome were compared between SMD groups with one-way A

154 HAE prodromes were associated with upregulation of multiple

155 Prodromes were mostly neurological but falsely evoked a

156 ation that subjects pass through an amnestic prodrome which is thought to reflect dysfunction of the

157 the level of sNfL in the multiple sclerosis prodrome, which would support a causative role of HHV-6A

158 dividuals who are not in a neurodegenerative prodrome, while greater use of this diagnosis in clinica

159 at begins in late life may be part of the AD prodrome, while recurrent depression may be etiologicall

160 5 patients with sudden-onset syncope without prodromes who had a normal heart and normal electrocardi

161 nts affected by sudden-onset syncope without prodromes who had a normal heart and normal electrocardi

162 cally, human MPV disease first has a febrile prodrome with lymphadenopathy followed by a diffuse macu

163 Treatment during the HAE prodrome with rhC1-INH was as effective at preventing pr

164 ients with acute viral myocarditis and viral prodrome within 2 weeks from the onset, which includes 3