ライフサイエンスコーパス: productively

1 ssive motors are predicted to cooperate more productively.

2 ease-related HRQoL and one's ability to work productively.

3 nsitions that allow them to continue folding productively.

4 to abstract subject matter, and combine them productively.

5 c S1 site, only Lys11-linked chains can bind productively across the active site and stimulate cataly

6 variability, suggesting that researchers may productively adopt a systems-level approach to conceptua

7 targets substrates to the proteasome can be productively amplified at the proteasome.

8 similarity metrics are increasingly used to productively analyze genome-wide data.

9 understand how reovirus inclusions differ in productively and abortively infected MDCK cells, we used

10 Bovine trypsin productively and correctly processed proHD5 in vitro but

11 This allows Kif15 dimers to productively and efficiently generate forces that could

12 on of its conduct in ways that respectfully, productively and equally involve local partners.

13 try as well as the fates of HIV-1 genomes in productively and nonproductively infected macrophages.

14 late strong IFN responses, fail to replicate productively, and can become WT revertants.

15 Biostatistics can be productively applied to cardiovascular research if inves

16 lso known as Markov random fields, have been productively applied to diverse problems in biology, inc

17 ognition were first being fashioned and used productively, are revisited.

18 folding efficiency, R264C molecules that do productively assemble into heterodimers are capable of c

19 different combinations, with a given B cell productively assembling only one combination.

20 unclear whether these existing models could productively be combined.

21 e area in which evolutionary information can productively be exploited is in aligning a new sequence

22 stead de novo enzymatic reactions could more productively benefit from optimization of the electrosta

23 ed on the assumption that the enzymes should productively bind DNA substrate first, followed by templ

24 ts showed that although RNA-binding proteins productively bind specific RNAs to control their functio

25 d, E449K accelerates the dissociation of non-productively bound complexes and inactive synaptic compl

26 avoring pre-synaptic (PS) complexes over non-productively bound complexes.

27 on of FSPP directly mimics that expected for productively bound FPP, with the exception of the precis

28 le to determine the crystal structure of SOX productively bound to a 31 nucleotide K12-2 fragment.

29 insight into how to use this biomarker more productively by distinguishing subsets of patients and b

30 likely assist mutant Aer proteins to signal productively by forming collaborative signaling teams.

31 TPase activity, support yeast viability, and productively chaperone the Hsp90 client glucocorticoid r

32 ce topography is removed, and results can be productively compared with those previously observed for

33 s suggests that different sample sets can be productively compared.

34 this process can be prevented in disease and productively controlled by design.

35 of dynamic conformational fluctuations that productively couple into the reaction coordinate.

36 potentially to ensure that iron oxidation is productively coupled to mineralization.

37 e that the flexible linkers may allow PKR to productively dimerize upon interaction with RNA activato

38 thought: Domain-general cognitive algorithms productively divide both linguistic and nonlinguistic in

39 ata reveal that MeV polymerase is capable of productively docking directly to the nucleocapsid core.

40 romolecular structures is a prerequisite for productively doing structural bioinformatics.

41 Polymerases already productively elongating at the time of P-TEFb inhibition

42 gering an inactive polymerase at CYC1 into a productively elongating form.

43 This new catalytic system is able to productively engage aryl chlorides with reduction potent

44 r from those by which AP-1 and AP-2 adaptors productively engage clathrin in vesicle biogenesis.

45 tic receptor binding domain architecture can productively engage hACE2, but only the Urbani mutationa

46 To make informed decisions and to productively engage in public discourse, citizens need t

47 (100-fold less potent than DCs) and fail to productively engage KRN T cells at steady state and duri

48 PPARs and other metazoan nuclear receptors productively engage several distinct LXXLL motif-contain

49 rapidly boosted the capacity of NK cells to productively engage target cells and enabled NK cell res

50 d TLR4 ligand, lipopolysaccharide (LPS), but productively engage the mouse TLR4 (mTLR4)/myeloid diffe

51 ycosylated IgG variants can be engineered to productively engage with FcgammaRIIIA, as well as the hu

52 e, CD8-dependent spread of signal from a few productively engaged TCR to many other TCR can explain t

53 e Notch-dependent transcriptional complex is productively engaged.

54 interacts with extranucleosomal DNA when it productively engages its nucleosome substrate.

55 e a TCRalphabeta heterodimer's likelihood of productively engaging autoantigen, because they are perv

56 the likelihood of a TCRalphabeta heterodimer productively engaging autoantigen, because they are wide

57 Given that cytosolic CA represents "productively" entered cores, whereas vesicular CA repres

58 n mechanism of TDP1 inhibition that could be productively exploited for potential anticancer applicat

59 iant segregation cannot be verified could be productively explored with the combined approach illustr

60 eactive immune process is present in IPF can productively focus efforts toward identifying the respon

61 etabolite, placing the 2'-terminal phosphate productively for removal.

62 R crosstalk pathways can, therefore, be used productively for tailored therapeutic approaches, such a

63 idged Fe(II)-OO-pterin intermediate in WT to productively form Fe(IV)=O, which is responsible for hyd

64 rmational flexibility, such that the peptide productively forms both extended-chain and helical state

65 ings suggest that psychiatric illness may be productively formulated as dysfunction in transdiagnosti

66 Further, the half-life of productively HCV-infected cells, estimated from the seco

67 m heterologous systems are shown to interact productively, highlighting the potential of such interfa

68 ERV-K HML-2 expression profiles specific for productively HIV-1-infected primary human CD4(+) T cells

69 in the C57BL/6J mouse, but failed to infect productively human corneal epithelial cells.

70 Such virions were able to infect productively human dendritic cells located beneath the e

71 sed to (i) use the water sources of SSA more productively, (ii) improve nutritional outcomes and rura

72 rgeting pericyte differentiation in vivo may productively impact fibrotic kidney disease.

73 All H1N1 viruses replicated productively in airway cells; however, in contrast to se

74 8-Br-L-cIDPR potentially binds non-productively in an upside-down fashion.

75 ow that gamma34.5 deletion viruses replicate productively in and induce cellular damage in infected e

76 The fact that bovine FLUDV replicated productively in both the upper and lower respiratory tra

77 Inspired by the dynamic clamp used so productively in cellular neuroscience, the HDC allows a

78 These viruses replicated productively in HIV-1 receptor-expressing CrFK cells and

79 e to the inability of the virus to replicate productively in mammalian hosts.

80 HPIVs replicate productively in respiratory epithelial cells and do not

81 helial cell rearrangements are being studied productively in several tissues, the ventral epidermis i

82 al base within these pockets, (ii) interacts productively in the Michaelis complex with the substrate

83 tertiary amine of the catalyst are involved productively in the rate-limiting cyanide addition step.

84 negative, that influence whether a virus can productively infect a cell and cause disease in differen

85 Serological evidence suggests that CCHFV can productively infect a wide variety of species, but only

86 ng on the circumstances, M. tuberculosis can productively infect cells using different modes of entry

87 1 was severely debilitated in its ability to productively infect cells via CEACAM1a, while the invers

88 e in determining the extent to which JCV can productively infect cells.

89 of murine norovirus (MNV) and its ability to productively infect cultured murine macrophages and dend

90 34 downregulated by OrfA) cells but fails to productively infect either 104-C1 (CD134-positive) cells

91 Nine polyomavirus (PyV) species are known to productively infect humans.

92 frequencies are less fit in vivo and fail to productively infect important target organs, such as the

93 Here we report that hantaviruses productively infect LECs and that LEC infection by HPS c

94 However, C. trachomatis can productively infect mice when the lower genital tract is

95 Asp14 are critical for A. phagocytophilum to productively infect mice, and immunization against their

96 s, human cytomegalovirus (HCMV) is unable to productively infect most cancer-derived cell lines.

97 fects macrophages and microglia and does not productively infect neurons or astrocytes.

98 owever, it is not clear how viruses adapt to productively infect new hosts.

99 y to traverse an intact nuclear envelope and productively infect nondividing cells is a salient featu

100 The failure of AAV2 to productively infect normal keratinocytes could be clinic

101 eduction of the ability of wild-type SV40 to productively infect permissive monkey cells, even when t

102 om canine, equine, avian, and seal origin to productively infect pigs.

103 ly synthesizing DNA; however, VZV is able to productively infect them and use their machinery to repl

104 We were able to productively infect with MDV B cells isolated from splee

105 The virus productively infected alveolar epithelial and mesenchyma

106 wed that the population of Ki-67+ cells were productively infected and expanded proportionally with l

107 Therefore, FoxP3(+) Treg cells are productively infected and play an important role in acut

108 principal targets of HIV-1 infection, become productively infected and survive long enough to return

109 , is not readily detectable in the nuclei of productively infected bovine cells during the late stage

110 trikingly, >95% of these dying cells are not productively infected but instead correspond to bystande

111 XS52 cells were productively infected by a vaccinia virus mutant lacking

112 gocytes (macrophages and microglia) that are productively infected by HIV in brains play a pivotal ro

113 The number of cells in the brain that are productively infected by HIV-1 is relatively small and c

114 ident central nervous system (CNS) cell type productively infected by HIV-1, and play a key role in t

115 While macrophages are another cell type productively infected by HIV-1, few studies have examine

116 Our data show that even though DCs are productively infected by HIV-1, infection does not induc

117 stem for establishing cell lines that can be productively infected by human T-lymphotropic virus type

118 rikingly, lung migratory CD103+ DCs were not productively infected by influenza virus and thus were a

119 re recruited to the granuloma where they are productively infected by M. marinum.

120 However, the skin cell type productively infected by MCPyV remains a central questio

121 that primary human osteoblasts (hOBs) can be productively infected by RRV.

122 DCs are productively infected by RSV, and during RSV infections,

123 CD4+ and CD8+ T cells were productively infected by RSV.

124 Here, we report that CNCCs are productively infected by ZIKV, but not by the related de

125 n of cytotoxic effector cells and killing of productively infected CD4 T cells.

126 described here we compared the frequency of productively infected CD4(+) T cells and macrophages in

127 le mechanisms may contribute to the death of productively infected CD4+ T cells and innocent-bystande

128 g (and thus latently infected) T cell when a productively infected cell attempts cell-to-cell transmi

129 t women may either produce fewer virions per productively infected cell or more effectively clear ext

130 ith latent envelope genomic fragments in the productively infected cell population.

131 rotein of HIV is expressed on the surface of productively infected cells and can be used as a target

132 trate that IL-7 enhances viral production in productively infected cells but does not disrupt viral l

133 el significantly overestimates the number of productively infected cells generated.

134 target cell population size on the number of productively infected cells generated.

135 This is demonstrated by reduced levels of productively infected cells in lymphoid organs and lower

136 s that will permanently reduce the number of productively infected cells or permanently silence the c

137 emia decay post-ART indicates a half-life of productively infected cells ranging from 4 to 9.5 h, i.e

138 We show that CTLs kill productively infected cells significantly faster (P = 0.

139 with cell extracts, viral DNA replication in productively infected cells utilizes additional viral an

140 ntribution of CD8 T cell-mediated killing of productively infected cells was earlier and much greater

141 Prevalence of virus with latent fragments in productively infected cells was observed in only 2% of s

142 y transcribing, EdU-labeled HIV-1 genomes in productively infected cells, and immunofluorescence anal

143 aded via the ubiquitin-proteasome pathway in productively infected cells, before latency establishmen

144 to capture interactions among target cells, productively infected cells, latently infected cells, vi

145 ients reflects immune-mediated death/loss of productively infected cells, the second-phase decline in

146 he expression patterns differed from that in productively infected cells, with the rat neuron pattern

147 -dependent recruitment of Hsc70 to nuclei of productively infected cells.

148 f virions and with detection of viral RNA in productively infected cells.

149 cella-zoster virus (VZV) in the cytoplasm of productively infected cells.

150 ption occurs in a subset of HIV-1 genomes in productively infected cells.

151 ve transcriptionally active HIV-1 genomes in productively infected cells.

152 and GlucII, and to operate in the context of productively infected cells.

153 ace of effective immune control measures for productively infected cells.

154 Herein, we show that the JHM strain also productively infected DCs.

155 ing RNAs was also verified by TaqMan qPCR in productively infected fibroblasts and ARPE19 cells.

156 EHV-1 productively infected four of these cell lines, and the

157 Sporozoites productively infected hepatocytes with high EphA2 expres

158 rs, and it is unclear how these cells become productively infected in vivo We investigated the mechan

159 the probability that a CD8(+) T cell will be productively infected is almost six times higher than fo

160 e protein transport during HIV-1 assembly in productively infected Jurkat CD4+ T cells and primary CD

161 A better understanding of the number of productively infected macrophages is crucial to further

162 , high levels of viremia are maintained from productively infected macrophages.

163 has already crossed the species barrier and productively infected mammals.

164 A ChIP assay using productively infected MeWo cells revealed that VZV ORFs

165 gorously assessed; however, the frequency of productively infected monocytes and macrophages in vivo

166 To assess the contribution of productively infected monocytes and macrophages to HIV-

167 eport the composition of small RNAs in HIV-1 productively infected MT4 T-cells.

168 Productively infected myeloid cells were detected in blo

169 In productively infected neuronal cultures, epinephrine tre

170 The MAC387(+) cells were not productively infected nor did they express detectable CC

171 Despite the relatively low frequency of productively infected SCM, we suggest that their quiesce

172 cells progress from the eclipse stage to the productively infected stage, the more likely that a vira

173 We find that most productively infected T cells migrate robustly, resultin

174 arly cloned viral genomes or by expansion in productively infected T cells.

175 cell follicles prevents their elimination of productively infected TFH cells.

176 During the acute phase, ZIKV productively infected the ovary causing accumulation of

177 fectious virus to CD4+ T cells without being productively infected themselves, and we point to a path

178 C. muridarum productively infected these macrophages at low MOIs but

179 cal and endocervical epithelial cells become productively infected with cell-free HIV-1 in a CD4-inde

180 use epithelial cells are the major cell type productively infected with Chlamydia during genital trac

181 with subtype A, B, C, or D SHIVs all became productively infected with different Env375 variants-S,

182 d, and only 45% of cultured neurons could be productively infected with either HSV-1 or HSV-2.

183 activated blood and tonsillar B cells can be productively infected with HHV-8, as measured by an incr

184 eLCs were productively infected with HIV, whereas Mutz-3 LCs were

185 estimating the rate at which CTLs kill cells productively infected with HIV-1 in humans in vivo.

186 Cells productively infected with HIV-1 release virions along w

187 However, Rag-gammac(-/-) mice were not productively infected with MNV by the oral route, in whi

188 NKT cells responded specifically to rare DCs productively infected with Nef- and Vpu-defective HIV-1.

189 hACE2-transduced mice were productively infected with SARS-CoV-2, and this resulted

190 asites owing to neonatal tolerization become productively infected with the filarial parasites.

191 we showed that the migrating monocytes were productively infected with the virus, documenting that t

192 s of NGS of RNA from fibroblasts and neurons productively infected with VZV using TaqMan quantitative

193 l particles than typically observed in cells productively infected with VZV.

194 posed to HTLV-1, both before and after being productively infected, can rapidly, efficiently and repr

195 porter mice to identify cells that have been productively infected, that have been rhoptry injected b

196 To determine whether tissue macrophages are productively infected, we used 3 different but complemen

197 ins determines whether or not a cell becomes productively infected.

198 ual HSV-infected neurons will be latently or productively infected.

199 ponding to those that are both activated and productively infected.

200 , a significant fraction of these cells were productively infected.

201 normally nonpermissive mouse cells to become productively infected.

202 ng waterfowl species, certain mammals can be productively infected.

203 The virus productively infects a small fraction of the blood DCs t

204 in the kidney and after entering the brain, productively infects and destroys oligodendrocytes.

205 We found that dengue virus productively infects approximately 80% of primary human

206 above observations, OrfA-negative FIV-34TF10 productively infects CrFK (CD134-negative) and 104-C1-Or

207 ich the OrfA reading frame is open (OrfArep) productively infects CrFK, GFox, 104-C1, and 104-C1-OrfA

208 68 efficiently completes the lytic phase and productively infects cultured cells.

209 have previously shown that dengue virus (DV) productively infects immature human dendritic cells (DCs

210 gerhans cells and that EBV both latently and productively infects oral epithelium-resident cells that

211 Moreover, ZIKV productively infects stem-cell-derived human neural cres

212 We found that vaccinia virus productively infects XS52 cells, yet this infection disp

213 introduction of fluorine into a molecule can productively influence conformation, pKa, intrinsic pote

214 rder to improve their well-being-that can be productively integrated into the framework of interperso

215 uction in a receptor-independent manner, and productively interact with a GPCR in isolated membranes.

216 of CFTR's second membrane-spanning domain to productively interact with amino-terminal domains.

217 Our data indicate that Sf6 can productively interact with other bacterial OmpAs as long

218 ie T-cell activation, specifically that they productively interact with signaling microclusters at th

219 assay, suggesting that H77 NS4B is unable to productively interact with the Con1 replication machiner

220 ance to a viral oncoprotein can nevertheless productively interact with the same cellular target.

221 ability to collect human genetic data and to productively interpret and apply it.

222 ersal and the mechanism by which sporozoites productively invade hepatocytes will be highlighted in t

223 x nature of diet and its associations can be productively investigated with disease-specific studies.

224 o calculate the percentage of cells that are productively, latently, or abortively infected.

225 of helicase are employed, Y122A is unable to productively load the helicase onto forked DNA substrate

226 lymph node, where the cells must be able to productively lodge and grow.

227 s that otherwise neurotoxic glutamate can be productively metabolized by glutamate oxaloacetate trans

228 ssue, tumor cells appear rounded and fail to productively migrate.

229 As such, they provide targets by which to productively mobilize resident progenitor cells of the a

230 and Myt1l do not access fibroblast chromatin productively on their own; instead, Ascl1 recruits Brn2

231 targets for HIV infection, that they become productively or latently infected at low levels, and tha

232 system revealed that T(SCM) cells can become productively or latently infected, although the vast maj

233 me-wide association studies (GWAS) cannot be productively performed using inbred mouse strains.

234 the substrate for the OSBS reaction is more productively positioned vis a vis the active site cataly

235 individual pre-messenger RNA transcripts are productively processed across different gene expression

236 Normal B cells that have failed to productively rearrange immunoglobulin V region genes enc

237 nt elimination of pre-B cells that failed to productively rearrange immunoglobulin VH-DJH gene segmen

238 ely essential role in the transcription of a productively rearranged Ig VDJCalpha transcription unit.

239 ckpoint (IgHCC), where the IgHC encoded by a productively rearranged Igh allele assembles into a PreB

240 In contrast to a productively rearranged Igh allele, the Igh messenger RN

241 does not regulate L chain expression from a productively rearranged Igk allele.

242 gel immunodiffusion assays, and inability to productively reassort with ICV led to the proposal that

243 hput platform for identification of antigens productively recognized by T cells.

244 BAP1 outside the UCH domain, each failing to productively recruit ASXH to the wild-type BAP1 catalyti

245 This allows both viruses to productively replicate in distinct sets of dividing cell

246 the dogma that mouse cytomegalovirus cannot productively replicate in human cells and found that mou

247 mian immunodeficiency virus (SIV) infect and productively replicate in macrophages and T lymphocytes.

248 The ability to productively replicate in macrophages is unique to H5N1

249 high morbidity and mortality in mammals, can productively replicate in macrophages, as measured by th

250 bility of certain influenza virus strains to productively replicate in macrophages.

251 small subset can overcome cellular blocks to productively replicate in murine and primary human macro

252 an (HPAI) H5N1 influenza virus strains could productively replicate in murine macrophages through a h

253 n resting, circulating memory B cells and to productively replicate in plasma cells.

254 stigated the ability of H1 to H16 viruses to productively replicate in primary murine alveolar macrop

255 the viruses with unprocessed polyprotein to productively replicate in the IFN-competent cells and in

256 ssociated with a strain-specific capacity to productively replicate in type II pneumocytes and to cop

257 to recruit factors to viral genomes that can productively replicate viral DNA in a recombination-depe

258 host species and the cell type in which they productively replicate.

259 orne B lymphocytes, while EBV intermittently productively replicates in mucosal epithelia.

260 and smaller than those formed by T3-T1M1, a productively replicating reovirus strain, and contained

261 ure localization of recombination factors to productively replicating viral genomes.

262 , unlike cells found in lymphoid organs that productively respond to acute infections, immune cells i

263 a marked reduction in their ability to glide productively, resulting in marked reduction in malaria t

264 periments have revealed that thymocytes must productively signal in response to self antigens to matu

265 ma viremia and a more rapid disappearance of productively SIV-infected cells from the lymph node comp

266 in the BchNB complex, but only one is bound productively, stalling Pchlide reduction in both active

267 istinct from the free drug in its ability to productively stimulate antitumor immunity.

268 In addition to amino acids, which have been productively studied for years, sugar-like molecules, ac

269 pes mutations in these specific genes may be productively studied to clarify ASD pathophysiology.

270 multiple myosinVa motors can cooperate more productively than collections of kinesins in COS-7 cells

271 he ability of multiple kinesins to cooperate productively, the spatial and temporal properties of app

272 es was highly sensitive to disruption by non-productively titrating lattice-forming self-interactions

273 ies demonstrate that murine PBLs can be used productively to identify potential correlates of protect

274 ensuring that switching occurs primarily and productively to the opposite type, called directionality

275 eatly enhances the amount of substrate bound productively to the thylakoids.

276 pproach presented to help clinicians respond productively to women who request intervention.

277 ctively capture the cargo in the cytosol and productively unload the cargo at the membrane.

278 g animals' ability to extract, identify, and productively use proportion information across a range o

279 that the systematic review approach could be productively used to inform the development of reference

280 st report of a virus evolving a mechanism to productively utilize an antiviral agent to stimulate its

281 torsion angle for assembly, mutants that can productively utilize the altered external scaffolding pr

282 In many cases of productively utilized frameshifting, the proportion of r

283 t at slippage-prone sequences also generates productively utilized products encoded trans-frame with

284 ly and multimeric protein complexes assemble productively, while minimizing the danger of protein agg

285 ly flexible C terminus allows La to interact productively with a diversity of noncoding RNA precursor

286 e showed the adenovirus proteinase interacts productively with its protein substrates in vitro and in

287 occurs in nature whenever a host is infected productively with more than one influenza A virus.

288 The Ski complex can engage productively with mRNA and extract it from 80S complexes

289 rmation, which is not predicted to associate productively with or activate downstream effectors.

290 addition, stage E2 cells proved to interact productively with primary BM stromal cells in ways that

291 and N-hydroxylamines were shown not to react productively with the alpha-ketophosphonic acids under t

292 tions within beta-strands, fail to associate productively with the Bam complex.

293 rase IV, not DNA polymerase II, could engage productively with the Escherichia coli replisome to bypa

294 To connect productively with the high resolution achieved by cognat

295 usions (FLPs), which enable them to interact productively with the surrounding extracellular matrix;

296 a traptamer determined whether it associated productively with the TMD of the human EPOR, the mouse E

297 the N-lobe must be Ca(2+)-bound to interact productively with this site.

298 t the N-lobe must be Ca(2+)-free to interact productively with this site.

299 at T cells also have the ability to interact productively with variant ligands, indicating a flexibil

300 Certain bat species can be productively yet asymptomatically infected with viruses