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1 ngs can be translated to human DCs and their progenitors.
2 able, likely due to low frequency of mutated progenitors.
3 dynamically marks a range of dental and bone progenitors.
4 stogenesis from Fndc5-transgenic bone marrow progenitors.
5 Notch1 is expressed by and active in TEC progenitors.
6 ematopoietic colony-forming units and T cell progenitors.
7 rcuit of autoregulation operating in nephron progenitors.
8 y and lack silenced chromatin like embryonic progenitors.
9 programs the development of ILC2s from their progenitors.
10 11b + and CD11b- cells, and in hematopoietic progenitors.
11 e fate of LTi progenitors versus non-LTi ILC progenitors.
12 in dexamethasone-treated PB and CB erythroid progenitors.
13 ected by increased maturation of erythrocyte progenitors.
14 rogramming of Muller glia into proliferating progenitors.
15 erive from multiple sources of hematopoietic progenitors.
16 ubunit of the E1 for neddylation in cortical progenitors.
17 ciated with impaired TEAD4 expression in CTB progenitors.
18 that eNePs are the earliest human neutrophil progenitors.
19 equires maintenance and expansion of myeloid progenitors.
20 and CD18, respectively, as markers of these progenitors.
21 was also detected in neonatal BAT and brown progenitors.
22 -beta in the development of ILC2s from their progenitors.
23 population of peritoneal basophil-mast cell progenitors.
24 PLV-LMCs do not derive from skeletal muscle progenitors.
25 essed preferentially and highly on erythroid progenitors.
26 ential for the differentiation of blood cell progenitors.
28 ferentiation of RGs into apical intermediate progenitors, a more restricted progenitor type lacking a
29 Conditional deletion of Hdac3 within myeloid progenitors accelerates healing of cortical bone defects
31 est that LumP and PrU cells have multipotent progenitor activity in organoid formation and tissue rec
32 e mice enhanced mammary epithelial cell stem/progenitor activity, elevated expression of estrogen rec
33 ee of which (L2/L3/L4) emerged from a common progenitor after the loss of the MmpS6/MmpL6-encoding Mt
34 m/progenitor cell, called adult human neural progenitor (AHNP) cells, that we found to be pathologica
35 eity within GMPs, it is unclear if committed progenitors already exist among these progenitors and ho
37 expression (marker of labyrinth trophoblast progenitors), altered maternal blood space, decreased fe
39 tified 25 candidate cell types that included progenitor and differentiating states with computational
43 imple design principle of organ growth where progenitors and differentiated cells expand in harmony w
44 lidation defined the transcriptomes of naive progenitors and erythroid-, megakaryocyte-, and leukocyt
45 mitted progenitors already exist among these progenitors and how they may behave differently during i
46 ot clear what promotes transition of ISCs to progenitors and how this fate decision is established.
49 ll-autonomous effect of MyHC-emb on myogenic progenitors and myoblasts is mediated by the fibroblast
52 neage bias, increased generation of lymphoid progenitors and rebalanced HSC lineage output in transpl
53 ional activity and accumulation of erythroid progenitors and that it may do so in an AhR-dependent fa
54 of pDCs from bone marrow dendritic cell (DC) progenitors and their maintenance is driven by the trans
55 in bone marrow and spleen became multipotent progenitors and, occasionally, some HSCs gave rise to me
56 controlling the level of Shh activity in pMN progenitors, and also regulates the allocation of oligod
57 id-, megakaryocyte-, and leukocyte-committed progenitors, and we identified CD44, CD326, ICAM2/CD9, a
58 lary ECs and respective resident endothelial progenitors appear to be at the origin of CCM lesions.
61 mes from embryonic day (E)7.5, when endoderm progenitors are specified, to E10.5 liver, when liver pa
64 cally defined culture system for distal lung progenitors as organoids derived from single adult human
65 In contrast, hPSC-derived HOXA(+) CD34(+) progenitors, as well as human cord blood CD34(+) cells,
66 sis (Arabidopsis thaliana) and their diploid progenitors, as well as one natural tetraploid and its s
68 self-renewal or differentiation of cortical progenitor behaviors in vivo, a variable we have termed
69 s (MPCs) and their segregation into bipotent progenitors (BPs) and unipotent pro-acinar cells (PACs).
70 (genome composition DDSS), and its putative progenitors, Brachypodium distachyon (DD) and Brachypodi
73 f human ACT products, we identified a memory-progenitor CD39-negative stem-like phenotype (CD39(-)CD6
74 monstrate that in the hematopoietic stem and progenitor cell (HSPC) compartment aneuploid cells have
82 in 2D cultures of a human bladder epithelial progenitor cell line in a dose-dependent manner, achievi
84 r mechanisms that control epicardium-derived progenitor cell migration, and the functional contributi
88 elays epithelial invagination, and decreases progenitor cell proliferation and dental epithelium cell
92 Myogenesis includes sequential stages of progenitor cell proliferation, myogenic commitment and d
94 cells derived from an endogenous adult stem/progenitor cell, called adult human neural progenitor (A
95 e of the nuclear lamins in adult neural stem/progenitor cells (ANSPCs), underlies age-related alterat
97 a microenvironment for the growth of hepatic progenitor cells (HPCs) at the periportal area and subse
101 o healthy age-matched hematopoietic stem and progenitor cells (HSPCs) and correlate the proteomes to
106 mphoid-dominant human hematopoietic stem and progenitor cells (HSPCs) using clonal tracking in patien
107 in up to 60% of human hematopoietic stem and progenitor cells (HSPCs), without impairing cell viabili
109 rols proliferation of multipotent pancreatic progenitor cells (MPCs) and their segregation into bipot
111 Mutations in centrosome genes deplete neural progenitor cells (NPCs) during brain development, causin
118 tic deletion of Dnmt3a and Dnmt3b in nephron progenitor cells (Six2 (Cre) Dnmt3a/3b) and kidney tubul
119 to study mammalian regeneration, where stem/progenitor cells (the "blastema") completely regenerate
120 e we show that acute responses to alcohol in progenitor cells altered gene expression in their descen
122 ries of mouse embryonic stem cells, neuronal progenitor cells and differentiated neurons and identify
123 on and disease progression that involve stem/progenitor cells and inflammation in a tissue-specific m
124 antage by enhancing self-renewal of stem and progenitor cells and inhibiting their differentiation.
128 ll RNA-seq and lineage-tracing, we find that progenitor cells are the principal targets of ageing, wh
130 ining (LR) and non-LR hematopoietic stem and progenitor cells both had indistinguishable localization
131 on's disease (PD) tissue sources: (a) neural progenitor cells derived from an endogenous adult stem/p
134 Transcriptomic profiling of cortical neural progenitor cells derived from these hiPSCs identified al
135 Many tissues are produced by specialized progenitor cells emanating from epithelia via epithelial
136 ditory sensory epithelium-the organ of Corti-progenitor cells exit the cell cycle in a coordinated wa
138 distinguishes the pathological detachment of progenitor cells from the normal delamination of daughte
139 y clears SCs and rejuvenates tissue stem and progenitor cells in naturally aged mice without causing
140 1 receptor type 1) on hematopoietic stem and progenitor cells in the bone marrow and stimulates granu
141 in(-)Sca-1(+)c-Kit(+) hematopoietic stem and progenitor cells in the bone marrow and the production o
144 of the proliferative capability of the crypt progenitor cells in vivo, lack of crypt base columnar st
145 rmal proliferation of hematopoietic stem and progenitor cells is critical for development of new appr
146 mmatory environment promotes oligodendrocyte progenitor cells maturation and myelin regeneration acro
147 mbal melanocytes with limbal epithelial stem/progenitor cells on fibrin hydrogels pre-incubated with
149 Deleting Gata3 enhances adult prostate stem/progenitor cells self-renewal capacity in both organoid
150 reduced mitochondrial density, and the brown progenitor cells sorted from offspring BAT demonstrated
151 mouse stress erythropoiesis use signals and progenitor cells that are distinct from steady-state ery
152 The lateral plate mesoderm (LPM) forms the progenitor cells that constitute the heart and cardiovas
153 jection neurons arise from a uniform pool of progenitor cells that lines the ventricles of the forebr
155 MTG16 repress transcription in the earliest progenitor cells to promote exit of ISCs from their nich
156 eating these diseases is to utilize stem and progenitor cells to replace neurons in situ, with the ex
157 addition of second heart field (SHF) cardiac progenitor cells to the poles of the heart tube results
159 and concurrent activation of oligodendrocyte progenitor cells with subsequent remyelination.SIGNIFICA
160 is to associate molecular differences among progenitor cells with their capacity to generate mature
161 ial magnetic stimulation, intracerebral stem/progenitor cells) that consider precise lesion location
162 progeny of a defined population of dividing progenitor cells, a daunting task in the developing cent
164 a major regulator of mammary epithelial stem/progenitor cells, and its activity is dysregulated under
165 spleen, thymus, and haematopoietic stem and progenitor cells, as well as in CD8(+)CD28(-) T cells fr
166 s at the base of the primary cilia in neural progenitor cells, causing an atypical non-genetic ciliop
167 hich both pathways are activated in stem and progenitor cells, LSCs expanded under chemotherapy-induc
168 through specific autophagic flux blockade in progenitor cells, which may have potential therapeutic i
178 system (MPS) is a family of cells including progenitors, circulating blood monocytes, resident tissu
179 eage population, damage-associated transient progenitors (DATPs), that arises during alveolar regener
182 lin Tuba8, transiently expressed in cortical progenitors, drives differentiation of RGs into apical i
184 are key regulators of the biology of neural progenitors during development and in adult neurogenic n
185 ontractility also impaired movement of basal progenitors during hair placode morphogenesis and dimini
189 both neuroepithelium cells and radial glial progenitors follow the same developmental trajectory dur
190 PCs; an initial wave of lymphomyeloid-biased progenitors, followed by precursors of hematopoietic ste
191 fferentiated in vitro from embryonic retinal progenitors for the effects of aging and, independently,
192 encing revealed that epidermal developmental progenitors form a more uniform population compared with
196 ) is expressed predominantly in granule cell progenitors (GCPs) in the cerebellum, as was shown in Jd
197 ramatic loss of the CNV and reversion to the progenitor genotype and drug susceptibility phenotype.
198 (hPSCs) revealed that HOXA(neg/low) CD34(+) progenitors give rise to NK cells that, similar to murin
199 entiation skewed toward granulocyte-monocyte progenitors (GMP) during joint and intestinal inflammati
200 odomain transcription factor promotes neural progenitor identity in the lateral ganglionic eminence (
201 C26UCA led to developmental arrest of B cell progenitors in bone marrow; poly-reactivity of the VRC26
202 es may promote expansion of abnormal myeloid progenitors in del(5q) MDS, and in rare cases drive the
203 dinate both the proper positioning of B cell progenitors in the bone marrow (BM) microenvironment and
204 caused by epigenetic rewiring of multipotent progenitors in the bone marrow, which overcomes the immu
208 wide range of cell types produced by single progenitors in the neocortex of mice may result from sto
209 er, the proliferative potential of adipocyte progenitors in vivo is unknown (Faust et al., 1976; Faus
210 lymph are increased and act on nearby midgut progenitors inducing Ecdysone-induced-protein-75B (Eip75
211 Hnf4a promotes the differentiation of PT progenitors into mature PT cells by regulating the expre
212 onic raphe nucleus-derived neural stem cells/progenitors into the lesion site of completely transecte
213 controlling the differentiation of committed progenitors into these cell types, however, are incomple
214 reducing proliferative reserve in blood-cell progenitors is causal has important public-health implic
215 found that AXL interacts with hematopoietic progenitor kinase 1 (HPK1) and demonstrate that HPK1 dow
216 -seq on neurons derived from Nestin-positive progenitors labeled by tamoxifen induction at embryonic
221 e in neurogenesis in both dorsal and ventral progenitor lineages and, if so, whether it regulates com
222 pressed the YAP1 target gene and mesothelial progenitor marker mesothelin, and many mesothelin-positi
223 of mature myeloid cells or their bone marrow progenitors, mediates sustained increased responsiveness
225 ls of the mononuclear phagocyte system (MPS; progenitors, monocytes, macrophages, and classical dendr
227 a rheostat to control BMP activation in the progenitor niche to determine regenerative outcome in fi
229 rrow (BM)-resident or circulating myeloid OC progenitors (OCP) expressing the receptor CX(3)CR1.
231 riticum turgidum ssp. dicoccoides, WEW), the progenitor of both modern tetraploid and hexaploid wheat
233 rs of diverse coronaviruses (CoVs) including progenitors of Severe Acute Respiratory Syndrome (SARS)-
234 from Cre-tdTomato reporter mice specific for progenitors of skeletal myocytes (Pax7(+) and MyoD(+)) a
235 imed to investigate the influence of myeloid progenitors on CD34(+) cell differentiation into CD56(+)
238 f hepatocyte markers with no impact on liver progenitors, other endodermal lineages, or vasculature.
242 ungs, the density and function of epithelial progenitor populations and the epithelial gene expressio
244 ered by a single population of developmental progenitors presenting a fixed fate imbalance of self-re
248 MPK activator metformin decreases epithelial progenitor proliferation and increases acid-secreting pa
249 nsic systems, purinergic signaling regulates progenitor proliferation during retinogenesis and regene
251 e marrow-derived macrophages and bone marrow progenitors promoted M2-like macrophage polarization and
252 ological features different from multipotent progenitors, raising the possibility that an intermediat
253 Bcl3, and Id2, which render pDCs and late DC progenitors refractory to physiological stimuli controll
256 fspring show microcephaly and primary neural progenitors require Cep55 and ESCRT for survival and abs
257 iency of TGF-beta receptor II in bone marrow progenitors results in inefficient development of ILC2s,
258 ession analysis of mirn23a-deficient myeloid progenitors revealed a decrease in TLR and IFN signaling
259 neurons and glia originate from radial glial progenitors (RGs), a type of stem cell typically extendi
261 irect evidence that oncogene-induced loss of progenitor self-renewal is driven by eIF2B5-mediated tra
264 ancreatic differentiation capacity up to the progenitor stage, but favor somatostatin- and pancreatic
266 differentiation through a paraxial mesoderm progenitor state that generates BAs at high efficiency.
268 The indica-type promoter is present in a progenitor subspecies O. nivara and thus was acquired ea
269 l cell divisions of outer radial glial (oRG) progenitors, suggesting cellular functions of LIS1 in re
272 red ejecta mass(3,4) could be explained by a progenitor system that is asymmetric in terms of the ste
274 e developing human infant liver, we identify progenitor targeting, delivery efficiencies, and suppres
276 Neural stem cells (NSCs) are multipotent progenitors that are responsible for producing all of th
277 give rise to numerous cell types, including progenitors that expressed the prolactin receptor (PRLR)
279 velop in the bone marrow from haematopoietic progenitors that have numerous shared characteristics be
280 KIR genes are densely methylated in NK cell progenitors, there is an implied stage of human NK cell
281 represses muscle differentiation in vascular progenitors, thus restricting these cells to a vascular
282 n protocols and mapped hPSC-derived myogenic progenitors to an embryonic-to-fetal transition period.
285 e show that ZBED2 can repress the pancreatic progenitor transcriptional program, enhance motility, an
286 ories reveals that late-stage retinal neural progenitors transcriptionally overlap cell states observ
287 intermediate progenitors, a more restricted progenitor type lacking attachment to the basal lamina.
290 we report that the functionality of vascular progenitors (VP) generated from normal and disease-prime
291 nt protein widely used as a marker of neural progenitors, was recently found to be expressed transien
292 filament protein highly expressed in neural progenitors, was recently identified in developing neuro
293 erences for three types of endogenous neural progenitors, we provide evidence for the differential ad
296 Gsx2 interactions are enriched within LGE VZ progenitors, whereas Ascl1-Tcf3 (E-protein) interactions
297 proliferative capacity of human hippocampal progenitors, which may subsequently impact on human cogn
298 h a reduced number of proliferating neuronal progenitors while mutant ugdh zebrafish do not phenocopy
300 mic coverage of young and old mouse HSCs and progenitors, with broader implications for understanding