ライフサイエンスコーパス: prognostic

1 Level III Prognostic STUDY TYPE:: Prognostic.

2 ted gene set; only LIN28B CTC expression was prognostic.

3 n most patients and its presence is strongly prognostic.

4 icentric study was to develop and evaluate a prognostic (18)F-FDG PET/CT radiomic signature in early-

5 ores, which could improve our diagnostic and prognostic ability and could guide treatment.

6 nal validation in 258 patients confirmed the prognostic ability of the score and demonstrated better

7 p of a clinical model significantly improved prognostic accuracy (C-index increase, 0.157 [0.056-0.25

8 characteristic curve was assessed to compare prognostic accuracy between models with and without PROs

9 d examined whether markers could improve the prognostic accuracy of clinical scoring systems, includi

10 M diagnostic constructs, also provide better prognostic accuracy over time and in addition lead to en

11 Prognostic analyses were applied to identify predictors

12 ith rigorous cross-validation procedures and prognostic analyses, we show that deep featurization bet

13 tions (GAs) occur in several cancers, may be prognostic and are actionable.

14 s (CTCs) has been considered as an appealing prognostic and diagnostic approach for cancer patients.

15 T-cell populations in vivo, which may serve prognostic and diagnostic roles.

16 This post hoc study sought to determine the prognostic and predictive impact of the WHO-defined mole

17 ng during and after NAC prior to surgery has prognostic and predictive value in early TNBC patients.

18 The aim of this study was to evaluate the prognostic and predictive value of HLA-G and HLA-F prote

19 promoter methylation status is accepted as a prognostic and promising predictive biomarker in gliobla

20 CRP and Ki-67 index were also prognostic and remained independent prognosticators afte

21 highlighted its importance as a diagnostic, prognostic and staging marker of FTD.

22 east cancer brain metastases and support the prognostic and therapeutic clinical utility of this path

23 ve shown tremendous success in achieving the prognostic and therapeutic goals for early prognosis and

24 ells (CTCs) from blood samples has important prognostic and therapeutic implications for cancer treat

25 their immense contribution in optimizing the prognostic and therapeutic modalities, biological intera

26 port that Epsin 3 (EPN3) is an oncogene with prognostic and therapeutic relevance in breast cancer.

27 -microenvironment interactions that may have prognostic and therapeutic relevance.

28 Our findings lay the foundation for accurate prognostic and therapeutic stratification of SOC.

29 Therefore, identification of new diagnostic, prognostic and therapeutic tools to tackle glioblastomas

30 ft tissue tumors; reappraisal of diagnostic, prognostic, and therapeutic approach to ocular adnexal t

31 al development could lead to new diagnostic, prognostic, and therapeutic approaches.

32 er improvement in miRNA-based diagnostic and prognostic applications.

33 nterventions, thereby, offering an immediate prognostic approach as the cornerstone to delivering suc

34 o treatment decisions, we aimed to develop a prognostic assay that integrates multiple data types for

35 MGMT promoter methylation status remained prognostic at tumor recurrence.

36 Ht volume is a prognostic biomarker for antidepressant treatment outcom

37 expression of ADAR and it could be used as a prognostic biomarker for disease progression, especially

38 mismatch computational scores as a potential prognostic biomarker for primary alloimmunity and its ap

39 Genomic CNV may be a novel prognostic biomarker for WHO grade IV glioma patient out

40 As a result, the performance of a prognostic biomarker may be accurate after a specific ti

41 ructural MRI, DWMA volume was an independent prognostic biomarker of Bayley Motor scores ([Formula: s

42 bjectively quantified DWMA is an independent prognostic biomarker of long-term motor development in v

43 RGS12 as a potential therapeutic target and prognostic biomarker of OSCC.

44 ession of miR-21 was a potential independent prognostic biomarker of poorer OS (HR = 1.27, 95% CI: 1.

45 HSP-7 patients, both in terms of diagnostic/prognostic biomarkers and novel pharmacological targets.

46 the pathological mechanisms and reveal novel prognostic biomarkers and therapeutic strategies for CRC

47 ve the potential to be promising diagnostic, prognostic biomarkers and therapeutic targets in breast

48 nsidered as a source of novel diagnostic and prognostic biomarkers as well as therapeutic targets for

49 findings reveal the challenges of developing prognostic biomarkers for patients with IBD and the impo

50 Sensitive and specific diagnostic and prognostic biomarkers for prostate cancer (PCa) are urge

51 To identify novel prognostic biomarkers in EOC, here we determined the exp

52 Here, we present a resource of SaB prognostic biomarkers.

53 dence of hazard mediation relationships with prognostic capacity useful for designing interventions.

54 luate demographic, clinical, laboratory, and prognostic characteristics and outcome measures of these

55 ailable, this study revealed the genetic and prognostic characteristics of female patients with lung

56 significantly stratified AML patients in two prognostic classes.

57 After adjustments for prognostic confounders, DOAC pretreatment was associated

58 t the prevalence, clinical associations, and prognostic consequences of malnutrition in patients with

59 ers about PC principles and developing clear prognostic criteria for when and how to integrate PC on

60 f training to deliver PC along with no clear prognostic criteria on when to initiate PC.

61 The optimal prognostic cutoffs for burden of COVID-19 pneumonia as d

62 agnostic findings, management strategies and prognostic data for these non-atherosclerotic mechanisms

63 ee.Objectives: To analyze the diagnostic and prognostic differences between tracheobronchial aspergil

64 tify whether size measurements increased the prognostic discrimination index (C-statistic).

65 All size measures significantly improved prognostic discrimination index by GEP class, as shown b

66 Incorporation of tumor size enhances the prognostic discrimination index of the GEP test in patie

67 Using a prognostic Earth system model, we show that a 0.1 increa

68 ve impact of IRF on vision and weak positive prognostic effect of SRF.

69 have ESKD is often shaped by their hopes and prognostic expectations related to kidney transplant.

70 pDS to NAC was a significant prognostic factor for better recurrence-free survival (P

71 The presence of TDs is an independent prognostic factor for DFS in patients with stage III CC.

72 1 and CHRM3, respectively) represent a worse prognostic factor for PCa progression free survival.

73 y sentinel node biopsy (SNB) is an important prognostic factor for T1 melanoma.

74 ivity was consistently revealed to be a poor prognostic factor in BM and PB.

75 without neoadjuvant therapy and serves as a prognostic factor in EAC.

76 The Ki-67 index is an established prognostic factor in gastrointestinal neuroendocrine tum

77 d on a sequencing method, are an independent prognostic factor in microsatellite stable stage II CRC.

78 oma in ORCH and PC-RPLND specimens was not a prognostic factor in this large retrospective study of p

79 h C-peptide >252 pmol/L emerging as the best prognostic factor.

80 mrEMVI status was again the only significant prognostic factor; furthermore those who showed a good t

81 Other highly-ranked genes included proposed prognostic factors (CXCL10, CD4, CD3E) and investigation

82 oped a risk stratification system from known prognostic factors and assessed it in the context of ris

83 performed incorporating treatment and common prognostic factors as covariates.

84 tic review and meta-analysis to identify all prognostic factors for advanced colorectal neoplasia (aC

85 dy was to establish the disease severity and prognostic factors for disease outcome by analysing freq

86 - and long-term outcome and to determine the prognostic factors for end-stage kidney disease patients

87 gery, and duration of epilepsy are important prognostic factors for outcomes of epilepsy surgery.

88 Morbidity was significant independent prognostic factors for overall survival (Relative Risk:

89 on, and gene expression of TAM phenotypes as prognostic factors for overall survival in lung cancer.

90 utated TP53, BIRC3, and SF3B1 as independent prognostic factors for PFS with GClb, whereas for VenG,

91 Prognostic factors for surgery included CD diagnosis dur

92 ultivariate Cox analyses were used to assess prognostic factors for survival.

93 Genetic parameters are established prognostic factors in chronic lymphocytic leukemia (CLL)

94 l studies are needed to further characterize prognostic factors in pediatric CD and to evaluate the i

95 Independent prognostic factors include age >=65 years, fever, GCS sc

96 Prognostic factors independently associated with an ACO

97 describe the characteristics and analyze the prognostic factors of EE in the GAMES cohort.

98 Knowledge of the prognostic factors of PCa and the bone metastasis patter

99 Despite selection using known prognostic factors survival is varied and morbidity and

100 out COVID-19 grows, more will be known about prognostic factors that can guide these difficult decisi

101 Prognostic factors to initiate stepdown included medicat

102 The evidence for all prognostic factors was categorized as "weak", "moderate"

103 ght rely on severity scores that incorporate prognostic factors, bowel damage assessment and non-inva

104 based on the therapeutic question, potential prognostic factors, including age, tumor location, M sta

105 d models were built by combining independent prognostic factors.

106 l hazards models to adjust for known adverse prognostic factors.

107 ies reporting long-term sequelae, HRQoL, and prognostic factors.

108 Adverse prognostic features of the cohort included short median

109 inical outcomes in MS, and to identify early prognostic features of these outcomes.

110 an update on the epidemiology, clinical and prognostic features, and diagnostic approach to patients

111 nal validation, the RSClin risk estimate was prognostic for DR risk in the Clalit registry (P < .001)

112 tic disease and healthy individuals, and was prognostic for stage IV patients.

113 CT/CT of bone scans performed at baseline is prognostic for survival in mCRPC patients treated with (

114 production number, Rt, is a key time-varying prognostic for the growth rate of any infectious disease

115 Currently, prognostic gene-expression signatures do not exist for a

116 and III patients into sufficiently distinct prognostic groups that potentially could be used to guid

117 Four histologic prognostic groups were identified (< 18 months with low

118 D8(+) T-cell density revealed three distinct prognostic groups with respect to disease-specific survi

119 ssion stratified the cohorts into 3 distinct prognostic groups.

120 ed with or without PCI and has an equivalent prognostic impact as post-discharge MI.

121 However, its prognostic impact in patients with acute coronary syndro

122 polymerase chain reaction and evaluated the prognostic impact of NPM1mut MRD and the effect of gemtu

123 2020 report on the prognostic impact of perineural invasion (PNI) and desmo

124 histotypes characterized by a heterogeneous prognostic impact.

125 LA strain provided additional prognostic implication over clinical information and con

126 xercise-induced pulmonary congestion carries prognostic implications is unknown.

127 us meta-analysis of its diagnostic accuracy, prognostic implications of adverse coronary plaque featu

128 pments in diagnosis and risk prediction, and prognostic implications of AF and its complications.

129 first study to use CMR to assess independent prognostic implications of functional TR.

130 enital heart disease, but the prevalence and prognostic implications of hepatorenal dysfunction are u

131 to characterize mechanistic determinants and prognostic implications of VE/VCO2 in a single-center dy

132 al (LA) pathophysiological changes and their prognostic implications using cardiovascular magnetic re

133 on to diagnostic accuracy, gene fusions have prognostic implications, such as unfavorable prognosis o

134 requently altered in patients' gliomas, with prognostic implications.

135 of the participants of the PRIMID-AS study (Prognostic Importance of Microvascular Dysfunction in As

136 These data highlight the prognostic importance of noncardiac organ-system dysfunc

137 Despite increasing understanding of the prognostic importance of vascular stiffening linked to p

138 pisodes of HF worsening were common, were of prognostic importance, and were reduced by dapagliflozin

139 nization of intratumor T-cell populations is prognostic in some cancer types.

140 Accordingly, we developed and validated a prognostic index (PIUKALL) that integrates multiple risk

141 ss age groups, HIV status, and International Prognostic Index risk groups.

142 The International Prognostic Index was statistically significant, with low

143 hough resistance to GCs is a strong negative prognostic indicator in T-ALL, the mechanisms of GC resi

144 aluation of alcohol withdrawal symptoms as a prognostic indicator of prazosin's efficacy in the treat

145 entration can serve as an independent strong prognostic indicator of short-term mortality in COVID-19

146 A key prognostic indicator of the intensity of deep convective

147 (MH) size is important because it is a major prognostic indicator of treatment success.

148 Of particular interest was to determine the prognostic influence of induction type: rabbit antithymo

149 y, Apgar scores at 5 and 10 minutes provided prognostic information about neonatal survival among pre

150 nderstand the underlying cause or to provide prognostic information are critical to reducing the morb

151 Lung shape could hold prognostic information for age-related diseases that aff

152 ritable markers but do not carry independent prognostic information for clinical outcomes in the UK B

153 r biomarkers of recent infection can provide prognostic information of TB disease risk in individuals

154 This provides important prognostic information to guide counseling of affected f

155 show that deep learning can add substantial prognostic information to the interpretation of 12-lead

156 No further prognostic information was conferred by ALN status in pa

157 expression, suggesting SPP1 mRNA a stronger prognostic marker candidate compared to tumor tissue OPN

158 Although CA19-9 is an established prognostic marker for patients with PC, it is unclear ho

159 It would thus be a useful prognostic marker for preventive patient management and

160 has the potential to be used as an important prognostic marker for the detection of lung and gastric

161 findings suggest the potential of SOX2 as a prognostic marker in EGFR-mutant lung cancer, as SOX2-me

162 Ralpha activity, where USP11 may represent a prognostic marker in ERalpha(+) breast cancer.

163 GPX4 is also a prognostic marker in patients with PDAC.

164 1 and provide a basis for the development of prognostic markers for advanced BLCA.

165 and ACTR6) from RNA-seq served as potential prognostic markers for lung cancer, and M2 predominance

166 7; p<0.0001) after adjusting for established prognostic markers significant in univariable analyses o

167 Identifying prognostic markers to better identify those at risk of l

168 g and neurophysiological data; their role as prognostic markers, considering their ability to predict

169 ndependent of current clinical and molecular prognostic markers.

170 orrelated with poor survival and unfavorable prognostic markers.

171 ing algorithms identified four factors for a prognostic model that was validated in internal and exte

172 The aim of this study was to produce a prognostic model to help predict posttransplant survival

173 We derived a combined prognostic model using retrospective clinical-pathologic

174 A validated prognostic model was developed to assist in determining

175 redicting mortality were also assessed and a prognostic model was developed, calibrated and validated

176 pwise regression techniques, when developing prognostic models in individuals with CR.

177 The development and validation of reliable prognostic models is a recognised research priority.

178 s end, we harnessed ML to build personalized prognostic models to predict DGF.

179 ve successfully leveraged TCGA data to build prognostic models, most efforts have focused on specific

180 te signature genes to serve as diagnostic or prognostic molecular markers are unknown.

181 We also analyzed prognostic molecular pathways by integrating genomic and

182 d PPIN nodes occur frequently in CRC and are prognostic of poor patient outcomes.

183 n early age in children with asthma would be prognostic of reduced lung function growth patterns over

184 to six grades with a previously established prognostic ordinality: grade 1 = no disease progression;

185 Interestingly, prognostic outcomes of many cancer types have been linke

186 k for progressive disease indicated by worse prognostic outcomes, increased frequency of cancer progr

187 id carcinoma (PC) and determine its clinical prognostic parameters.

188 e that gene expressions have slightly better prognostic performance, and that most of the gene expres

189 mutated genes derived here show substantial prognostic power and suggest specific vulnerabilities of

190 estingly, Ki-67 index and CRP influenced the prognostic power of PD-L1.

191 I therapy and they may have an impact on the prognostic power of PD-L1.

192 The prognostic power of somatic alterations is highly variab

193 nown pan-cancer miRNA signature with patient prognostic power.

194 allelic state is critical for diagnostic and prognostic precision in MDS as well as in future correla

195 Our study aimed to develop and validate a prognostic prediction model for severe maternal outcomes

196 become powerful tools in disease diagnosis, prognostic prediction, and dynamic monitoring of therape

197 However, up to date, its prognostic predictive capability has not been investigat

198 cal cohort to establish S6K1 expression as a prognostic/predictive biomarker.

199 ent Boosting-Colon is an independent machine prognostic predictor which allows stratification of stag

200 n be used to stratify groups of patients for prognostic purposes or for therapeutic trials.

201 therapeutic, diagnostic, epidemiologic, and prognostic purposes.

202 also serve as a biomarker for diagnostic and prognostic purposes.

203 DNA methylation patterns for diagnostic and prognostic purposes.

204 ox regression was performed to determine the prognostic relevance of MRI-derived myocardial strain fo

205 Their prognostic relevance regarding disease conversion was de

206 clinical outcomes in CHB patients and assess prognostic risk factors.

207 A prognostic risk index of three genes (FABP3, CD36 and RA

208 ess heterogeneity of scar, and evaluated its prognostic role in patients with hypertrophic cardiomyop

209 extent of MGMT promotor methylation and its prognostic role is independent from other molecular mark

210 s could provide better information about the prognostic role of hypoxia-inducible angiogenic pathway

211 cy in a variety of malignancies, data on the prognostic role of PD-L1 in MPE is scarce.

212 The clinical relevance and the potential prognostic role of persistently negative (1,3)-beta-D-gl

213 This study aimed to clarify the prognostic role of primary tumor location in NSCLC.

214 ged patients with COVID-19, FIB-4 may have a prognostic role.

215 bserved that PKR and PI4K2A play significant prognostic roles in breast cancer patients.

216 response as measured by the modified Glasgow prognostic score (mGPS) and the neutrophil to lymphocyte

217 patients, with an increasing accuracy of the prognostic score and with different underlying assumptio

218 study was to derive and evaluate a combined prognostic score associated with distant metastasis-free

219 The HER2DX combined prognostic score identifies patients with early-stage, H

220 A prognostic score that reflects the mortality risk and an

221 eath (p = 0.00001) while controlling for the prognostic score with logistic regression.

222 ing techniques trained to predict a clinical prognostic score, the Nkam score.

223 developed CT scores, two different clinical prognostic scores (Liou and CF-ABLE), forced expiratory

224 tatus improves the predictive performance of prognostic scores for in-hospital mortality in patients

225 n independently of the Revised International Prognostic Scoring System (IPSS-R)(11).

226 egories according to a Revised International Prognostic Scoring System (IPSS-R).

227 ce among other widely available, noninvasive prognostic scoring systems.

228 for OC and inclusion of MTV observations in prognostic scoring.

229 has been less prominently explored than for prognostic signatures.

230 rations in AA and PNH and will explore their prognostic significance and mechanisms of clonal selecti

231 lure with reduced ejection fraction, but its prognostic significance for at-risk individuals with pre

232 , providing evidence that genomic tests have prognostic significance in non-selected DLBCL patients.

233 ified PERCIST, PET-based response maintained prognostic significance in patients classified as having

234 Here, we show that circulating ITLN1 has prognostic significance in patients with advanced ovaria

235 Functional neuroimaging, which has prognostic significance, has yet to be explored in this

236 We aimed to assess their long-term prognostic significance.

237 with novel subtypes of childhood B-ALL, have prognostic significance.

238 nts a correlate of functional diversity with prognostic significance.

239 ve numerous SVs, which should be pursued for prognostic significance.

240 mportance of molecular phenotypes in patient prognostic stratification.

241 toma Risk Group Data Commons to validate the prognostic strength of the underlying INPC criteria and

242 Level III Prognostic STUDY TYPE:: Prognostic.

243 g of age and INPC criteria will identify new prognostic subgroups.

244 There is no prognostic test to ascertain whether cervical intraepith

245 fering a means of developing a predictive or prognostic test.

246 performed to identify the optimal cutoff for prognostic threshold of AVA.

247 ma p-tau181 as a non-invasive diagnostic and prognostic tool for AD, regardless of clinical stage, wh

248 tudy showed the CTS5 model could be a useful prognostic tool for predict long-term survival in HoR+/H

249 for AGYW and underscore the need for diverse prognostic tools considering epidemic severity, age, sex

250 s can then serve as potential biomarkers and prognostic tools for LUAD.

251 ls for enhanced diagnosis and monitoring for prognostic use towards point-of-care testing.

252 nderlying causes, while others clarified the prognostic usefulness of MRI in hypertrophic cardiomyopa

253 t radiography has not been validated for its prognostic utility in evaluating patients with coronavir

254 These findings reinforce the prognostic utility of serial KCCQ-OS assessments to iden

255 ds models were fit to assess the independent prognostic value and interaction between AI-ECG AF model

256 Baseline PSA had no prognostic value for response prediction.

257 sease in patients, but its genetic basis and prognostic value in a population-based cohort have not b

258 Molecular classification has strong prognostic value in high-risk EC, with significantly imp

259 Our study aimed to validate its prognostic value in large-scale population and explore t

260 genetic signature of autophagy had negative prognostic value in patients with breast cancer, inverse

261 ssed series of DLBCL patients, iPET had good prognostic value interpreted either visually or semiquan

262 We also investigated the prognostic value of (18)F-DOPA PET/CT at the same time p

263 he present study was to assess the long-term prognostic value of (18)F-FDG PET imaging for risk strat

264 Purpose To analyze the prognostic value of a chest radiograph severity scoring

265 ur objective was to evaluate the independent prognostic value of a novel MRI biomarker-objectively di

266 , or cardiovascular death) and evaluated the prognostic value of aortic valve calcium score and bioma

267 (ratio of stroke volume to ejection time) on prognostic value of AVA <=1.0 cm(2) for time to death wa

268 Transvalvular flow rate determines prognostic value of AVA in AS.

269 aimed to evaluate the effect of flow rate on prognostic value of AVA in AS.

270 Flow rate had a significant effect on prognostic value of AVA.

271 This study aimed at evaluating the prognostic value of B-line assessment during exercise in

272 The aim of this study was to assess the prognostic value of baseline clinical and high resolutio

273 th AD during progression to flare state, the prognostic value of baseline microbiome configurations h

274 The prognostic value of CAC, beyond ischemic burden, suggest

275 ess the predictors, clinical correlates, and prognostic value of diurnal CSR in upright position.

276 The prognostic value of double mutation was evaluated with a

277 on maps and provide further insight into the prognostic value of DTCs for metastatic organotropisms.S

278 We aimed to evaluate the prognostic value of early PSA changes after (177)Lu-labe

279 regressions were performed to determine the prognostic value of inducible ischemia or late gadoliniu

280 However, the prognostic value of LV GLS in secondary MR has not been

281 This study sought to demonstrate the prognostic value of LV GLS over LVEF in patients with se

282 The prognostic value of microvesicles (MVs) for midterm graf

283 We also discuss the prognostic value of mutant p53 and current status of the

284 However, thanks to the prognostic value of partial metabolic response assessed

285 We sought to investigate the prognostic value of proteinuria after conversion to SRL.

286 pathogenesis of the disease, we analysed the prognostic value of SASH1 in non-small cell lung cancers

287 ts diagnostic value as well as its important prognostic value on consciousness recovery.

288 as recently drawn attention for its clinical prognostic value, although its capacity to predict morta

289 LDH was the marker with the strongest prognostic value, and elevated LDH increased the risk fo

290 ts' baseline characteristics had significant prognostic value, guiding appropriate subject selection

291 that metabolic response assessment has added prognostic value, potentially improving therapeutic deci

292 n the tumor microenvironment provides strong prognostic value, which is increasingly important with t

293 assaying EGFR and HER3 together may improve prognostic value.

294 text of RCC and its potential predictive and prognostic value.

295 ndent samples and testing longitudinally for prognostic value.

296 me, and PSA velocity, suggesting it may have prognostic value.

297 ents, and further assessed its diagnostic vs prognostic value.

298 effusion on initial CT chest have potential prognostic values, the features more commonly observed i

299 Outcomes were adjusted for prognostic variables and analyzed using Cox regression.

300 f TDT, adjusted for influence of established prognostic variables on outcomes.