ライフサイエンスコーパス: program of

1 ng of cancer cell lipid metabolism towards a program of 1) exogenous sphingolipid scavenging independ

2 Cohort A included 19 programs of 44 applicants (January 1, 2017, to September

3 eptember 30, 2017), and cohort B included 39 programs of 47 applicants (October 1, 2017, to June 30,

4 h 9 of 16 (56%) patients completing the full program of 6 weeks.

5 Through direct programming of a continuous electromagnetic interface at

6 Selective and linear programming of a redox transistor array is executed in p

7 tivity contributes to the aberrant molecular program of ABC-DLBCL via its dual ability to modulate bo

8 voluntary contracting system yields a small program of about 1,840 ha of land conversion in a 279,00

9 onscious representations encompass the motor programming of actions that could be accomplished congru

10 ic reticulum (ER) and orchestrates a complex program of adaptive cellular remodeling.

11 f dynamin-1 in cancer cells contributes to a program of "adaptive" CME that alters signaling to enhan

12 ur findings reveal a mechanism of early life programming of adult adiposity, which is mediated by pri

13 nd place it as a critical regulator of fetal programming of adult metabolic disease.

14 homeostasis and regeneration are mediated by programs of adult stem cell renewal and differentiation.

15 We aimed to determine if a program of aerobic and resistance exercise could safely

16 specific complexities in the transcriptional programming of Ag-specific ASC populations.

17 Our data suggest that developmental programming of aging importantly contributes to (and per

18 and CD8(+) lineages, matched differentiation programs of agonist-signaled cells to their MHC specific

19 d a long-read technology-based WGS screening program of all first-episode methicillin-resistant Staph

20 vaccine (IPV) into the routine immunization programs of all countries using oral polio vaccine (OPV)

21 mplicity of the t2M/t4M binding site enables programming of allostery in RNAs, recoding oligo-U domai

22 rns a complex posttranscriptional regulatory program of alpha-1-antitrypsin expression.

23 influenza A virus (IAV) also induces a broad program of alternative splicing of host genes.

24 Strikingly, this program of alternative splicing was reversed in vitro an

25 genes while restricting the gene expression program of alternative Th fates.

26 and antidepressant responses via epigenetic programming of an xCT-mGlu2 network.

27 hromatin regulation via CoREST as central to programming of ant social behavior, with potential far-r

28 n profiles, consistent with a shared genetic program of appendage regeneration.

29 it directly activates a core transcriptional program of approximately 100 genes with diverse biologic

30 le to derive and compare the gene expression programs of ASC subsets that were responding to the same

31 ariability in the composition and functional programs of ascites cells, including immunomodulatory fi

32 findings indicate a conserved developmental program of barrier acquisition between zebrafish and mic

33 esponse that largely recapitulates molecular programs of barrier establishment.

34 vel function of Id1 in BAT thermogenesis and programming of beige adipocytes in white adipose tissue

35 Thus, taking advantage of the program of blood lead testing in Arizona, condor blood s

36 Metabolic programming of bone marrow stromal cells (BMSCs) could i

37 SPARC suppressed metabolic programming of both adipocytes and OvCa cells and exerte

38 ents a critical checkpoint in the functional programming of both IL-17- and IFN-gamma-producing gamma

39 tempt to accelerate genetic gain in breeding programs of both animals and plants.

40 ition-stress interplay in pregnancy on fetal programming of brain development are beginning to emerge

41 ch to expand on this important area of fetal programming of brain development.

42 ne the role of the fetal PT in developmental programming of brain function by maternal melatonin and

43 To identify kidney-specific and shared programs of branching morphogenesis, comparative express

44 ial lipid metabolism and the differentiation program of breast cancer cells, thereby revealing a prev

45 val signaling is critical for the metastatic program of cancer cells.

46 to total Google search volume, and National Program of Cancer Registries recorded cancer incidence a

47 Surveillance, Epidemiology, and End Results program of cancer registries, we estimated CRC incidence

48 o 2013, at the state level, per the National Program of Cancer Registries.

49 y described that tailoring the rate-response programming of cardiac implantable electronic devices in

50 contributions of each of these stressors to programming of cardiovascular dysfunction.

51 lutionarily conserved means to ensure proper programming of CD8(+) and CD4(+) T cell responses to vir

52 brate brain development depends on a complex program of cell proliferation and migration.

53 Metastasis requires a coordinated program of cellular changes that promote increased survi

54 develop engineering-driven approaches to the programming of cellular functions that could yield trans

55 evelopmental arrest to test whether parallel programs of cellular differentiation and gene expression

56 After inducing a transcriptional program of centriole biogenesis, E2f4 forms apical cytop

57 oligosaccharides (HMOs), is associated with programming of child growth remains unknown.

58 om the National Key Research and Development Program of China (Grant No.

59 National Key R&D Program of China, Ministry of Science and Technology of

60 National Key Research and Development Program of China, National Natural Science Foundation of

61 National Key R&D Program of China, National Natural Science Foundation of

62 ction, National Key Research and Development Program of China, National Science Foundation of China.

63 cience Foundation of China, National Key R&D Program of China, Natural Science Foundation of Zhejiang

64 National Key R&D Program of China, Project of Humanities and Social Scien

65 her Education Institutions, National Key R&D Program of China, Science Foundation for Distinguished Y

66 ID-19, National Key Research and Development Program of China, the Beijing Science and Technology Pro

67 The National Key Research and Development Program of China.

68 To circumvent these problems, a program of clinical standardization was embedded in the

69 nvironmental stimuli on mechanisms governing programs of CNS myelination under normal and pathologica

70 whole genomes, to elucidate the core genetic program of complex multicellularity and fruiting body de

71 rating this enhanced diversity into breeding programs of conventional and underutilized crops could h

72 o future stress through enhancement of known programs of cortical plasticity.

73 Drug discovery programs of covalent irreversible, mechanism-based enzym

74 ession could open new avenues in engineering programs of cyanobacterial strains.

75 molecular explanation for DC-ASGPR-mediated programing of DCs to control host immune responses.

76 In addition, ex vivo programming of DCs with fms-related tyrosine kinase 3 li

77 at oncogenic KRAS promotes a gene expression program of de novo lipogenesis in non-small cell lung ca

78 and advancing computer-assisted planning and programming of deep brain stimulation.

79 homology mediated events, we demonstrate the programming of deletion patterns by introducing microhom

80 ium screening, and guideline) implementation program of delirium guidelines in adult ICUs.

81 expressed coincident with the timing of sex programming of developing oocytes by methyl farnesoate i

82 In our program of development of new N-acetylglucosaminephospho

83 x mutants (both XX and XY) initiate the male program of development, but later half of these gonads s

84 1 diabetes) were invited to participate in a program of diabetes education, metabolic staging, assess

85 The program of differentiation is determined, in part, by FO

86 that activates the terminal differentiation program of distal segments in the pronephros.

87 Our data defined the genetic programs of distinct lung T(RM) cell populations and sho

88 ce of information for describing the genetic programs of distinct static cell states; however, bulk m

89 live imaging of the developmental migration program of Drosophila primordial germ cells (PGCs), we s

90 perature-sensitivity of some transcriptional programs of E. coli.

91 In response, a program of early feasibility studies (EFS) has been deve

92 B-cell lines supporting the latency I or III program of EBV protein expression and is more complex th

93 ication, modelling, behaviour prediction and programming of electrochemically reconfigurable architec

94 er reprogramming activates a transcriptional program of embryonic foregut endoderm.

95 Using direct neuronal programming of embryonic stem cells, we found that two m

96 7 cells and promotes the pathogenic effector program of encephalitogenic Th17 cells by regulating GM-

97 initiating cells can co-opt the self-renewal program of endogenous stem cells as a means of enforcing

98 yses indicated that the normal developmental program of endosperm is fully executed under prolonged h

99 d up-regulation of conserved macrophage-like program of engulfment in chemotherapy-induced senescent

100 itors do not execute the adult morphogenesis program of enlargement, polyploidization, and proplatele

101 us, associated with execution of the genetic program of epidermal barrier formation, to a fully inact

102 Skin wound repair requires a coordinated program of epithelial cell proliferation and differentia

103 reased by p27 phosphorylation, and activates programs of epithelial-mesenchymal transformation and me

104 Interfering with this regulated program of events or depleting the immunofibroblasts in

105 This program of events, that precedes lymphocyte infiltration

106 s the possibility of establishing a unifying program of expression change at a genomic scale.

107 The metabolic programs of functionally distinct T cell subsets are tai

108 tients in 23 cancer types using two reliable programs of FusionScan and TopHat-Fusion.

109 P signaling pathway regulates the functional programming of gammadelta T cells.

110 and EMT (epithelial-mesenchymal transition) program of GBM cells by directly targeting DLGAP1.

111 increased transcription of a BDNF-dependent program of gene expression containing CRE binding sites,

112 ription factors SBF and MBF activate a large program of gene expression in late G1 phase that underli

113 it connects mTORC1 to a tunable and dynamic program of gene expression that is tailored to specific

114 of exine formation with the well-documented program of gene expression.

115 We conclude that a common deterministic program of gene regulation is sufficient to govern maint

116 Importantly we observed osteogenic programming of gene expression by released GET-RUNX2 (8.

117 RNA-seq analysis showed extensive re-programming of gene expression in the CS8 with 2073 gene

118 tional network specifying microglia-specific programs of gene expression and facilitate efforts to un

119 Programs of gene expression are executed by a battery of

120 enefit from the ability to turn on different programs of gene expression in response to conditions in

121 The execution of developmental programs of gene expression requires an accurate partiti

122 How SMAD2 activates programs of gene expression that are modulated over time

123 showed that IL-4 induced the expression of a program of genes including Arg1 and Ap1b1 in microglia,

124 atics analyses, the complete dynamic genetic programs of germ and granulosa cells from E16.5 to postn

125 and reveal a unique Tiam1-mediated molecular program of glutamatergic synapse regulation in dentate g

126 ta reveal a unique RhoGEF-mediated molecular program of glutamatergic synapse regulation in dentate g

127 critical role in the formation and metabolic programming of glycolytic myofibers in skeletal muscle.

128 and delamination, underlie the morphogenesis program of growing biofilms.

129 Aging disrupts the unique program of GSC cytokinesis, with GSCs failing to abscise

130 as diet and microbiota, regulate neurogenic programs of gut motility(2-5), but the underlying molecu

131 ntive cardiology, and to national policy and programs of health promotion, all of which were coincide

132 ong-term protective effects on developmental programming of hepatic lipotoxicity and inflammation in

133 ects offspring from WD-induced developmental programming of hepatic lipotoxicity and may help slow th

134 rus (HPV) needs to alter the transcriptional program of host cells.

135 K for host transcripts thereby leading to a program of host splicing changes that promote IAV replic

136 ur cell-autonomous approach enabled parallel programming of hPSCs into multiple cell types simultaneo

137 Thus, IRF4-dependent genomic programming of human migratory LCs appears to enable LC

138 GC functions and reveals essential molecular programs of humoral adaptive immunity.

139 ght to investigate the early transcriptional programs of hypoxic ECs by using RNA-Seq of primary cult

140 ct of a tailored multifaceted implementation program of ICU delirium guidelines on processes of care

141 While T-bet controls the type 1 programming of ILC3s, the molecular mechanisms governing

142 cal trials, manufacturer-specific, strategic programming of implantable cardioverter-defibrillators (

143 NA-sequencing to describe the unique genetic program of in vivo murine lung primordial progenitors an

144 ompartments obtained through a rapid autopsy program of individuals undergoing long-term ART.

145 senescence-associated secretory phenotype-a program of inflammatory cytokine gene activation.

146 inal maturation and effector differentiation programs of iNKT cells.

147 cription factors in regulating specification programs of innate and adaptive lymphocytes.

148 potentially applicable to other development programs of innovative therapies for patients with advan

149 nked to STAT6 transcription-factor-dependent programming of integrin alpha(V)beta(3) expression: Th2

150 his study is to report the experience with a program of Intensive Care to facilitate Organ Donation (

151 ethnically diverse sample (n = 147) from the Programming of Intergenerational Stress Mechanisms (PRIS

152 Remarkably, somatic genetic re-programming of intracellular clocks in SCN astrocytes wa

153 elements and safeguards a complex regulatory program of its target gene.

154 72601), and the Key Research and Development Program of Jiangsu Province (No.

155 unction as an additional tool for management programs of laurel wilt.

156 analysis may help to accelerate the breeding programs of lily through utilizing different genomes, un

157 hese results illuminate a previously unknown program of liver regeneration after acute injury and all

158 ng a new era of medicine through the genetic programming of living cells(1,2).

159 We suggest that the timing programs of long-distance migratory birds may have great

160 sferases/demethylases to redirect epigenetic programming of M(LPS + IFN-gamma)/M(IL-10) genes for its

161 r vascularization, a switch in the metabolic program of MARCO-expressing macrophages, and activation

162 Jiangsu Provincial Special Program of Medical Science.

163 become pigmented and enact a gene expression program of melanocyte differentiation.

164 ules may not represent a specific biological program of messenger ribonucleoprotein (mRNP) assembly,

165 We conclude that genetic programming of metabolism may be important for lineage d

166 ctin organization, inhibiting the mechanical program of metastasis.

167 p9x, and has major impact on the tumorigenic program of metastatic melanoma.

168 otential of alpha7nAChR agonists in early re-programming of microglia in neonates exposed to in utero

169 e found that p53 controls specific and broad programs of mTEC differentiation.

170 latory pathway regulates the differentiation program of multiple T cell subsets involved in T1D devel

171 his transcriptional pioneering during B cell programming of multipotent lymphoid progenitors by restr

172 While an innate program of myelin development proceeds independently of

173 ximity to specialized regions can affect the programming of myonuclei and functional compartmentaliza

174 The programming of nanomaterials at molecular length-scales

175 United Kingdom, funded Communities First, a program of neighborhood regeneration delivered to the 10

176 motor neurons to explore short and long-term programming of neural networks by using optical stimulat

177 ation of preclinical evidence of nutritional programming of neurobehavioral impairments.

178 an in vivo - in vitro model of developmental programming of neuroinflammation induced by lipopolysacc

179 s provided by the Developmental Therapeutics Program of NIH/NCI against a panel of pathogenic fungi i

180 A program of normothermic ex situ liver perfusion (NESLiP)

181 i and widely implicated in the developmental programs of numerous tissues.

182 the mechanisms underlying the developmental programming of offspring phenotype by suboptimal intraut

183 Our findings provide evidence of programming of offspring SBP trajectories by gestational

184 onstrate that neuronal TSC1/2 orchestrates a program of oligodendrocyte maturation through the regula

185 Lineage-specific programming of oligodendrocytes results from sensing env

186 articipating in an Italian compassionate-use program of ombitasvir/paritaprevir/ritonavir + dasabuvir

187 that microglia express a conserved core gene program of orthologous genes from rodents to humans, inc

188 subjective and objective wireless monitoring program of patient-centered outcomes can be carried out

189 These results reveal a morphogenetic program of patterned apical constriction governed by Shh

190 We evaluated a program of payments for ecosystem services in Uganda tha

191 To decipher the transcriptomic programs of pericytes during angiogenesis, we crossed Pd

192 but much less is known about the replication programs of plants.

193 turnover is part of the cell cycle-dependent program of polar development.

194 ly transient and late stable gene expression program of polarization.

195 neonatal challenges can result in long-term programming of poor offspring cardiovascular health.

196 sferases in establishing the transcriptional program of postnatal cardiomyocytes during heart develop

197 ren aged 2 to 5 years in Bavaria, Germany, a program of primary care-based screening showed an islet

198 iral CD8(+) T cells and was required for the programming of progenitor-like CD8(+) T cells.

199 ly transactivate a luminal androgen-receptor program of prostate oncogenesis.

200 Our work reveals a fetal-specific program of protective immunity whose dysregulation is as

201 sional (2D) silicon compartments that enable programming of protein assembly lines by local synthesis

202 stablished by the Association of Schools and Programs of Public Health for masters-level trainees, no

203 -aligned with the Association of Schools and Programs of Public Health's "Framing the Future" initiat

204 so be at the core of the work of schools and programs of public health.

205 We identified an emerging program of putative enhancers that revise H3.3 occupancy

206 Transcriptional programming of regulatory mechanisms facilitates the fun

207 study shows a 2-year beneficial effect of a program of rehabilitation maintenance on the BODE index

208 TGF-beta1 orchestrates the multifaceted program of renal fibrogenesis involving proximal tubular

209 The PGC has recently commenced a program of research designed to deliver "actionable" fin

210 g Screening Trial (NLST), and the UT Special Program of Research Excellence (SPORE) cohort.

211 iversity of Iowa and Mayo Clinic Specialized Program of Research Excellence (SPORE; N = 920; median f

212 ity of Iowa/Mayo Clinic Lymphoma Specialized Program of Research Excellence).

213 The cognitive-training program of research has showed no appreciable benefits,

214 efficacy in the CAPRISA (Centre for the AIDS Program of Research in South Africa) 004 trial.

215 This article draws on a program of research in three American cities-Boston, Chi

216 of the Center, we will lead a collaborative program of research that addresses self-care knowledge g

217 pulation Fund, UNICEF-WHO-World Bank Special Program of Research, Development and Research Training i

218 pulation Fund, UNICEF-WHO-World Bank Special Program of Research, Development and Research Training i

219 er and National Cancer Institute Specialized Programs of Research Excellence.

220 Following a program of resistance training, there are neural and mus

221 ad3 DNA binding leading to a transcriptional program of RhoGEFs that facilitate nMRTF activity.

222 Programming of risk is likely due to a combination of vu

223 e activation contributes in part to prenatal programming of risk.

224 , comprising deep learning and probabilistic programing of RNA-seq data, causally linked the loss of

225 entiation, providing insights into molecular programming of SC lineage progression and homeostasis.

226 fs for screening programs and decide whether programs of screening should be funded.

227 four catalytic residues that enabled the re-programming of SdCPS2 activity to afford four distinct p

228 This started a program of searches for mutants in fission yeast that re

229 The developmental program of seed formation, germination, and early seedli

230 nscription, with gene expression driven by a program of selective unmasking, translation, and degrada

231 n to any cell-autonomous, 'oncogene-induced' program of senescence.

232 an be arranged to bring about an algorithmic program of sequential genetic manipulations without the

233 NA accumulation just prior period of oocytes programming of sex.

234 C differentiation and is part of a conserved program of skeletogenesis among echinoderms.

235 sion have played a pivotal role in modifying programs of skeletogenesis within the phylum.

236 l system, may influence neurodevelopment and programming of social behaviors across diverse animal sp

237 However, programming of splicing patterns in engineered biologica

238 This study focuses on a program of standardized nursing and physical therapy int

239 However, traditional programming of stimulation parameters relies upon short

240 Here we demonstrate experience-dependent re-programming of stress-sensitive hypothalamic neurons, wh

241 ble that seeds recalled or renovated ancient programs of stress-induced growth arrest that were alrea

242 ualitative and quantitative methods within 1 program of study, is becoming increasingly popular to al

243 yrate groups between amides allow controlled programming of supramolecular hydrogen bonding and facil

244 his work brings us closer to molecular level programming of surface chemistry, with promising applica

245 e to increased heart weight at birth and the programming of susceptibility to hypertension in adultho

246 bunit composition confers specificity to the program of synaptic activity-regulated gene transcriptio

247 ving an important role in the cell-intrinsic program of T cell hyporesponsiveness and point to NR4A i

248 , molecules associated with inflammation and programming of T cells were minimally induced.

249 ones can directly alter gene transcriptional programs of T cells, we focus in this study on how sex h

250 A comprehensive program of TB case finding and treatment of TB infection

251 Here we identify distinct transcriptional programs of TEC that account for their age-specific prop

252 (n = 12) receiving the complete vaccination program of the currently used acellular pertussis vaccin

253 Seventh Framework Program of the European Commission, Swiss National Found

254 Moreover, the transcriptional program of the Flk1(+) mesoderm was maintained in the sm

255 red events reported to the pharmacovigilance program of the Food and Drug Administration and associat

256 inducible cell type-specific gene expression program of the human TNF/LT locus and provide an approac

257 esults are being applied in the conservation program of the Kihnu Native Sheep Society.

258 We obtained data from the SEER Program of the National Cancer Institute (NCI).

259 Intramural Research Program of the National Cancer Institute, National Insti

260 n Cancer Society and the Intramural Research Program of the National Cancer Institute.

261 rch was supported by the Intramural Research Program of the National Institutes of Health.

262 In the breeding program of the National Registry for Italian Queen Breed

263 orted by grants from the Intramural Research Program of the NIDDK, NIH (DK075112, DK075116, DK071013,

264 lished Antimicrobial Resistance Surveillance Program of the Philippines via a binational collaboratio

265 coordinate and maintain the transcriptional program of the platinum-resistant state in ovarian cance

266 unknown how the differentiation and effector program of the Th subsets in the periphery are regulated

267 Correct gene expression programming of the cardiomyocyte underlies the normal fu

268 in childhood pointing toward in utero immune programming of the child.

269 During pregnancy, programming of the fetal central nervous system establis

270 Programming of the immune system during fetal developmen

271 ghly vulnerable population, whereby pubertal programming of the PVN results in aberrant HPA axis resp

272 aused by LT-IH are mediated by epigenetic re-programming of the redox state in the CB chemosensory re

273 529 529 References 529 Re-programming of the transcriptome involves both transcrip

274 g how this protein leads to the selective re-programming of the translational landscape is critical.

275 cell hierarchies that mirror transcriptional programs of the corresponding normal lineages.

276 The training programs of the future will need to directly address the

277 nd Small Business Technology Transfer (STTR) programs of the National Cancer Institute (NCI) are cong

278 Here, we examine how the distinct motor programs of the nematode C. elegans are coupled together

279 programming effectors to both introduce fate programs of the target cell type and erase the identity

280 murine counterpart of human asthma) through programming of their NK cells; predisposition to AAD did

281 f Hlx at a physiological level drives a full program of thermogenesis and converts iWAT to brown-like

282 o vaccination by shaping the transcriptional program of these cells and making them more prone to str

283 ology and lifestyle, diurnal transcriptional programs of these organisms are similar.

284 e of early life ER stress in the nutritional programming of this metabolic disease.

285 Despite the large potential for uDCD, programs of this kind only exist in a reduced number of

286 Thus, cell-type-specific regulatory programs of tissue regeneration can be revealed by genom

287 the human fetal immune system defaults to a program of tolerance, there is concurrent need for prote

288 e suppression through T-cell inhibition, and programming of tolerogenic macrophages.

289 The project has also introduced a program of training for trainers for the personnel from

290 Many genes are subject to sophisticated programs of transcriptional regulation, mediated by DNA

291 two overlapping, extensive, and independent programs of translational repression across sporozoite m

292 sustaining mTORC1 activation and functional programming of Treg cells.

293 41 could contribute to the dedifferentiation program of tumor-forming keratinocytes and to molecular

294 sequencing for studying the transcriptional programs of tumor nuclei in frozen archival tissue sampl

295 Regulation of the programming of tumour-associated macrophages (TAMs) cont

296 tic receptors in primary T cells enables the programming of user-defined responses when designing T-c

297 Data from the UNIFI program of ustekinumab in patients with UC treated with

298 iling, we determined sex-specific adipogenic programming of WAT progenitors isolated from pups on the

299 rease of brown adipose activity and browning program of white adipose tissues.

300 related microcephaly clusters as a long-term program of work.