ライフサイエンスコーパス: programming of

1 within less than 5 s using fast temperature programming of a 0.5-m-long microbore column.

2 Through direct programming of a continuous electromagnetic interface at

3 node- derived and other local signals in the programming of a Hox pattern at posterior spinal levels.

4 Selective and linear programming of a redox transistor array is executed in p

5 ence and kinetics can be rewired through the programming of a sequence motif of the general form G-G/

6 fine a mechanism for Stat4-dependent genetic programming of a Th1-associated gene.

7 onscious representations encompass the motor programming of actions that could be accomplished congru

8 ur findings reveal a mechanism of early life programming of adult adiposity, which is mediated by pri

9 e GR and PGC-1alpha participate in the fetal programming of adult beta-cell function through inhibiti

10 Fetal growth plays a role in programming of adult cardiometabolic disorders, which in

11 overnutrition during pregnancy affect fetal programming of adult disease.

12 extend the concept of fetal and early infant programming of adult diseases to the immune system and s

13 of pregnancy complications and the in utero programming of adult diseases.

14 maturity in the Preterm Birth and Early Life Programming of Adult Health and Disease (ESTER) Study, a

15 maternal nutrition can induce developmental programming of adult hypertension in offspring.

16 nd place it as a critical regulator of fetal programming of adult metabolic disease.

17 idence in support of prenatal glucocorticoid programming of adult ND over 40 years in daughters only.

18 underlying fetal growth restriction and the programming of adverse health outcomes in the adult.

19 specific complexities in the transcriptional programming of Ag-specific ASC populations.

20 Our data suggest that developmental programming of aging importantly contributes to (and per

21 mplicity of the t2M/t4M binding site enables programming of allostery in RNAs, recoding oligo-U domai

22 As, and it is thought that this prevents the programming of an antiviral RNA-induced silencing comple

23 and antidepressant responses via epigenetic programming of an xCT-mGlu2 network.

24 hromatin regulation via CoREST as central to programming of ant social behavior, with potential far-r

25 r mineralization by directing the osteogenic programming of aortic progenitors in diabetic arterioscl

26 ults demonstrate that the cell type-specific programming of apparently committed primary progenitors

27 (Wnt) superfamilies, are also active in the programming of arterial osteoprogenitor cells during vas

28 ld be used as a control signal for automated programming of basal ganglia stimulators.

29 vel function of Id1 in BAT thermogenesis and programming of beige adipocytes in white adipose tissue

30 may partly arise from altered developmental programming of beta-cells.

31 odule for the Drupal CMS that simplifies the programming of bioinformatic Drupal modules.

32 tions related to implantation, hardware, and programming of biventricular devices.

33 Intrauterine programming of body composition [percentage body fat (%B

34 Metabolic programming of bone marrow stromal cells (BMSCs) could i

35 data provide key insights into the metabolic programming of border cells that strongly implicate a mo

36 SPARC suppressed metabolic programming of both adipocytes and OvCa cells and exerte

37 ents a critical checkpoint in the functional programming of both IL-17- and IFN-gamma-producing gamma

38 ition-stress interplay in pregnancy on fetal programming of brain development are beginning to emerge

39 ch to expand on this important area of fetal programming of brain development.

40 ne the role of the fetal PT in developmental programming of brain function by maternal melatonin and

41 y described that tailoring the rate-response programming of cardiac implantable electronic devices in

42 sight into how IGF-1 signaling modulates the programming of cardiac muscle gene expression.

43 igenetic modification of DNA methylation and programming of cardiac PKCepsilon gene repression in a s

44 ating cardiovascular aging and developmental programming of cardiovascular disease, and aging being d

45 ating cardiovascular aging and developmental programming of cardiovascular disease.

46 contributions of each of these stressors to programming of cardiovascular dysfunction.

47 lutionarily conserved means to ensure proper programming of CD8(+) and CD4(+) T cell responses to vir

48 that the LTbetaR/IFN-I axis is essential for programming of CD8(+) T cells to mediate immunopathology

49 identify a role for 1,25D3 in the molecular programming of CD8(+) T-cell conversion to an IL-13-secr

50 Functional studies show that programming of CD8+ T cells occurs early after initial a

51 lay a specific regulatory role in epigenetic programming of cell lineage because it is ubiquitously e

52 form studies of aging and enable the precise programming of cellular age in parallel to cell-fate spe

53 , and the GATA family, which participates in programming of cellular differentiation.

54 develop engineering-driven approaches to the programming of cellular functions that could yield trans

55 The programming of cellular networks to achieve new biologic

56 oligosaccharides (HMOs), is associated with programming of child growth remains unknown.

57 canola seed development disrupts the normal programming of Chl degradation, resulting in green seed

58 not amenable to selective ERRgamma-directed programming of classic exercise-like effects in the skel

59 -clustering algorithm (ChAT) employs dynamic programming of combinatorial histone modification profil

60 modifiable targets to prevent developmental programming of common diseases.

61 genetic mechanisms that govern developmental programming of cotton fiber morphogenesis in these two c

62 g a key role of Tsc1 in modulating metabolic programming of DC differentiation.

63 In addition, ex vivo programming of DCs with fms-related tyrosine kinase 3 li

64 and advancing computer-assisted planning and programming of deep brain stimulation.

65 homology mediated events, we demonstrate the programming of deletion patterns by introducing microhom

66 expressed coincident with the timing of sex programming of developing oocytes by methyl farnesoate i

67 tion of IL-2 to the expansion and functional programming of developing Tregs.

68 Developmental programming of diabetes in these mice was assessed from

69 stem (ES) cells can erase the developmental programming of differentiated cell nuclei and impose plu

70 in studying mechanisms involved in abnormal programming of differentiating estrogen-target tissues,

71 potential etiological mechanism for in utero programming of disease.

72 t had no significant affect on developmental programming of dissacharidases.

73 uggested to play a role in the developmental programming of dysmetabolism based on studies of human s

74 ection, we analyzed the requirements for the programming of effector and memory T cell development in

75 selective set of IL-12-induced genes to the programming of effector functions within the stable popu

76 ication, modelling, behaviour prediction and programming of electrochemically reconfigurable architec

77 Using direct neuronal programming of embryonic stem cells, we found that two m

78 reveal a role for the placenta in long-term programming of emotional behaviour.

79 estrogenic activity, are able to disrupt the programming of endocrine signaling pathways established

80 stable and regulated gene silencing through programming of endogenous microRNA pathways.

81 lifelong persistence of such "developmental programming" of energy balance.

82 ductive tissue which dictates organ-specific programming of epithelial tissues.

83 Preferential epigenetic programming of estrogen response after in utero xenoestr

84 selectively altered the normal developmental programming of estrogen-responsive genes via modificatio

85 s may contribute to sexual dimorphism in the programming of exaggerated cortisol regeneration in live

86 ced these cells in vivo, indicating abnormal programming of Fas-deficient T cells before the DNT stag

87 n this study, we provide evidence for immune programming of fetal loss in response to polyinosinic:po

88 Here, we describe the rational programming of function in a de novo designed di-iron ca

89 understanding the biosynthetic mechanism and programming of fungal PKSs.

90 P signaling pathway regulates the functional programming of gammadelta T cells.

91 In this way, temporal programming of gelation was possible under mild conditio

92 no known function and may contribute to the programming of gene expression and embryo development.

93 Importantly we observed osteogenic programming of gene expression by released GET-RUNX2 (8.

94 modifications and their exploitation in the programming of gene expression during several events in

95 offspring behavior by disrupting epigenetic programming of gene expression in the brain.

96 hypothesized that BPA may disrupt epigenetic programming of gene expression in the brain.

97 RNA-seq analysis showed extensive re-programming of gene expression in the CS8 with 2073 gene

98 tages of development, to the clearing and re-programming of gene expression necessary to transition f

99 between parental genomes, leading to altered programming of genes that promote the growth, stress tol

100 critical role in the formation and metabolic programming of glycolytic myofibers in skeletal muscle.

101 tpartum element in metabolic and immunologic programming of health of neonates.

102 ong-term protective effects on developmental programming of hepatic lipotoxicity and inflammation in

103 ects offspring from WD-induced developmental programming of hepatic lipotoxicity and may help slow th

104 t that RSK2 is involved in the prometastatic programming of HNSCC cells, through phosphorylation of p

105 tic islet formation, as well as to life-long programming of hormonal determinants of glucose homeosta

106 Studies of the programming of Hox patterns at anterior spinal levels su

107 he tailbud are primarily responsible for the programming of Hoxd10 at neural plate and the earliest n

108 ur cell-autonomous approach enabled parallel programming of hPSCs into multiple cell types simultaneo

109 e know relatively little about the molecular programming of HSCs during vertebrate embryogenesis.

110 Does developmental programming of human body weight regulation occur via ep

111 Thus, IRF4-dependent genomic programming of human migratory LCs appears to enable LC

112 duced steroids acutely to PNS rats overrides programming of hyperactive HPA axis responses to immune

113 imal tubular cells (RPTCs) could prevent the programming of hypertension and kidney disease in the of

114 he PVH appears to be required for early-life programming of hypertension arising from either maternal

115 the understanding of the mechanism of fetal programming of hypertension.

116 le for DNA methylation in mediating neonatal programming of hypoxic sensitivity and the ensuing auton

117 Programming of ICD therapies for tachyarrhythmias of 200

118 (Comparison of Empiric to Physician-Tailored Programming of ICDs [EMPIRIC], Multicenter Automatic Def

119 While T-bet controls the type 1 programming of ILC3s, the molecular mechanisms governing

120 eripheral environmental context in long-term programming of immune dysfunction.

121 lity to tuberculosis, possibly through early programming of immunity.

122 suggests possible implications for long-term programming of immunity.

123 Therefore, to explore the programming of immunological sensitization by the skin,

124 (Comparison of Empiric to Physician-Tailored Programming of Implantable Cardioverter Defibrillators T

125 cal trials, manufacturer-specific, strategic programming of implantable cardioverter-defibrillators (

126 The programming of implantable cardioverter-defibrillators (

127 e to the disruption of the normal epigenetic programming of imprinted loci in somatic tissues and/or

128 systems analyses with regard to the dynamic programming of innate leukocytes are lacking.

129 dverse conditions in utero, to developmental programming of insulin resistance remain unknown.

130 nked to STAT6 transcription-factor-dependent programming of integrin alpha(V)beta(3) expression: Th2

131 ethnically diverse sample (n = 147) from the Programming of Intergenerational Stress Mechanisms (PRIS

132 light evolutionarily conserved and divergent programming of intestinal DCs.

133 Remarkably, somatic genetic re-programming of intracellular clocks in SCN astrocytes wa

134 The mechanism of programming of iterative highly reducing polyketide synt

135 e fetal kidney, effects that likely underpin programming of kidney development and function by a mate

136 ossible mechanism for maintaining epigenetic programming of large-scale chromatin domains throughout

137 for prenatal growth, but evidence for fetal programming of later FM or central adiposity is weak.

138 leptin concentrations relative to fat mass, programming of leptin concentrations may be one mechanis

139 important implications for the intrauterine programming of life expectancy.

140 ng a new era of medicine through the genetic programming of living cells(1,2).

141 It allows programming of lytic phages to kill only antibiotic-resi

142 sferases/demethylases to redirect epigenetic programming of M(LPS + IFN-gamma)/M(IL-10) genes for its

143 nt of this receptor network in the metabolic programming of macrophages and dendritic cells (DCs), es

144 that miR-155 plays a key role in atherogenic programming of macrophages to sustain and enhance vascul

145 one marrow (BM) stem/progenitor cells in the programming of macrophages toward a proinflammatory phen

146 The results provide evidence of in vivo programming of macrophages within the retina.

147 Thus, intrinsic transcriptional programming of maternal serotonergic activity determines

148 ts suggest that RUNX1 may participate in the programming of megakaryocytic lineage commitment through

149 tor CTL, and demonstrate that IL-2-dependent programming of memory CD8(+) T cells capable of secondar

150 ent a novel strategy to offset dysfunctional programming of memory CD8+ T cells.

151 cells and nonhematopoietic cells blocked the programming of memory precursors essential for establish

152 nical intervention against the developmental programming of metabolic disease resulting from prenatal

153 tissues is fundamental to the developmental programming of metabolic syndrome, but underlying mechan

154 We conclude that genetic programming of metabolism may be important for lineage d

155 otential of alpha7nAChR agonists in early re-programming of microglia in neonates exposed to in utero

156 lpha (HIF1alpha) mediated this functional re-programming of monocytes, revealing a potential mechanis

157 nsistent with a role for Hcrt in the central programming of motor activity.

158 Here, we prove that metabolic programming of MSCs by oxygen tension directs chondrogen

159 In conclusion, metabolic programming of MSCs by oxygen tension provides a simple

160 his transcriptional pioneering during B cell programming of multipotent lymphoid progenitors by restr

161 ximity to specialized regions can affect the programming of myonuclei and functional compartmentaliza

162 The programming of nanomaterials at molecular length-scales

163 , implying a critical role for PGI(2) in the programming of "natural" gammadelta-17 cells.

164 neuronal ensembles and perform rapid genetic programming of neural circuits.

165 motor neurons to explore short and long-term programming of neural networks by using optical stimulat

166 ation of preclinical evidence of nutritional programming of neurobehavioral impairments.

167 an in vivo - in vitro model of developmental programming of neuroinflammation induced by lipopolysacc

168 RNA splicing plays a critical role in the programming of neuronal differentiation and, consequentl

169 To investigate the epigenetic programming of niche cells by Piwi, we screened mutation

170 However, epigenetic programming of niche cells remains unexplored.

171 These findings suggest that the programming of NK effector function results from defined

172 ociations provide some evidence for in utero programming of offspring appetite by maternal intake dur

173 rition during pregnancy is implicated in the programming of offspring for the development of obesity

174 Results do not support androgen programming of offspring ND.

175 the mechanisms underlying the developmental programming of offspring phenotype by suboptimal intraut

176 Our findings provide evidence of programming of offspring SBP trajectories by gestational

177 Lineage-specific programming of oligodendrocytes results from sensing env

178 fector cells that are generated but also the programming of ones that will differentiate into memory.

179 Msx 2, osterix, and RUNX2 are crucial in the programming of osteogenesis.

180 e the key intracellular pathways involved in programming of ovarian reserve.

181 e the key intracellular pathways involved in programming of ovarian reserve.-

182 del to explain our results combining genetic programming of overall vascular architecture with hemody

183 ters that may be fundamental to anticipatory programming of p53 response genes upon stress.

184 We conclude that programming of pancreatic insulin secretion responsivene

185 Genetic programming of peptidomimetic synthesis should facilitat

186 y in adult offspring, suggesting an in utero programming of PKCepsilon gene expression pattern in the

187 Recent studies demonstrate that fetal programming of PKCepsilon gene repression results in isc

188 o stress-induced jasmonates cause genetic re-programming of plant cells?

189 neonatal challenges can result in long-term programming of poor offspring cardiovascular health.

190 iral CD8(+) T cells and was required for the programming of progenitor-like CD8(+) T cells.

191 In an effort to perturb the programming of proliferation and differentiation in a su

192 sional (2D) silicon compartments that enable programming of protein assembly lines by local synthesis

193 nd networks with atomic accuracy enables the programming of protein interaction specificity for a bro

194 s the need for venous access and complicated programming of pumps.

195 the lumbosacral region to examine the early programming of regional characteristics within the poste

196 Transcriptional programming of regulatory mechanisms facilitates the fun

197 Programming of relative leptin concentrations by early d

198 ollution may play an important role in early programming of respiratory health and is potentially ame

199 isual function, likely through developmental programming of retinal dopamine.

200 Programming of risk is likely due to a combination of vu

201 e activation contributes in part to prenatal programming of risk.

202 ulators are key components for the intrinsic programming of RPCs and are essential for the formation

203 deployment of visuospatial attention and the programming of saccades are governed by the inferred lik

204 ibuted network of structures involved in the programming of saccadic eye movements.

205 entiation, providing insights into molecular programming of SC lineage progression and homeostasis.

206 four catalytic residues that enabled the re-programming of SdCPS2 activity to afford four distinct p

207 B cell subsets, we observed broad epigenetic programming of selective transcription factor binding si

208 meiosis, thereby enabling unique epigenetic programming of sex chromosomes for male reproduction.

209 NA accumulation just prior period of oocytes programming of sex.

210 l system, may influence neurodevelopment and programming of social behaviors across diverse animal sp

211 thways, especially those regulating vascular programming of solid tumors.

212 of speech', a disorder of motor planning and programming of speech.

213 matid-derived frog embryos, we show that the programming of sperm for successful development relates

214 However, programming of splicing patterns in engineered biologica

215 w such links between intrinsic and extrinsic programming of stem cells have been reported previously.

216 rocess, as well as the potential for ex vivo programming of stem cells toward a renal lineage.

217 en focused on niche signaling and epigenetic programming of stem cells.

218 Here, we review the epigenetic "programming" of stem cells into oligodendrocytes, by ana

219 However, traditional programming of stimulation parameters relies upon short

220 iding a system-wide view of the quantitative programming of storage carbohydrate metabolism.

221 methylation is functionally relevant for the programming of stress reactivity in the human brain.

222 Here we demonstrate experience-dependent re-programming of stress-sensitive hypothalamic neurons, wh

223 sponse to smallest errors and influences the programming of subsequent movements.

224 When searching with our eyes, parallel programming of successive eye movements ensures that vis

225 yrate groups between amides allow controlled programming of supramolecular hydrogen bonding and facil

226 his work brings us closer to molecular level programming of surface chemistry, with promising applica

227 lexible docking system, allows sophisticated programming of surface patches by the user via a facet r

228 e to increased heart weight at birth and the programming of susceptibility to hypertension in adultho

229 hat in contrast to expansion, the functional programming of T cell effector and memory responses in v

230 , molecules associated with inflammation and programming of T cells were minimally induced.

231 ta thus illustrate that Bcl6 is required for programming of T(FH) cell generation.

232 s, and highlight a central role of metabolic programming of T(reg)-cell suppressive activity in immun

233 lowing the fine-tuning of expression levels, programming of temporal dynamics, and control of microbi

234 T cells is critically required for the early programming of Th17 cell lineage and Th17 cell-mediated

235 However, current protocols for ex vivo programming of Th17 cells, which include TGFbeta exposur

236 splay (BIND) as a strategy for the molecular programming of the bacterial extracellular matrix materi

237 Correct gene expression programming of the cardiomyocyte underlies the normal fu

238 regnancy, protecting the fetus from abnormal programming of the cardiovascular system.

239 Recent studies suggest that developmental programming of the carotid body response to hypoxia invo

240 ress whether TRAIL plays a role in the early programming of the CD8(+) T cell response, we performed

241 -10 may be temporarily stimulatory; however, programming of the cells may be altered, resulting in di

242 isease risk is largely unknown, but in utero programming of the child's immune system may play a role

243 in childhood pointing toward in utero immune programming of the child.

244 ition (over and undernutrition) on perinatal programming of the CNS and immune system, and how this m

245 These results enabled the programming of the degradation rates of the DNA-assemble

246 During pregnancy, programming of the fetal central nervous system establis

247 l in consequent placental function and hence programming of the fetus.

248 The programming of the fungal polyketide synthase (PKS) is q

249 during spermatogenesis, including epigenetic programming of the future paternal genome during spermat

250 Prevention programming of the future will depend on all of us havin

251 The primary periods for epigenetic programming of the germ line are those associated with p

252 r there is a critical window for nutritional programming of the growth trajectory during the first 9

253 reactivity later in life, mediated via fetal programming of the HPA axis through decreased glucocorti

254 ess history, contribute to the developmental programming of the hypothalamic-pituitary-adrenal stress

255 Programming of the hypothalamo-pituitary-adrenal (HPA) a

256 rdioverter-defibrillators (ICDs), as well as programming of the ICD, is unclear.

257 entified but also results from inappropriate programming of the immune response.

258 Programming of the immune system during fetal developmen

259 nd study design considerations, 3) microbial programming of the immune system, 4) the microbiome and

260 , we explored the possibility of temperature programming of the latter step.

261 blood formation, further distinguishing the programming of the long- and short-term blood population

262 this experiment revealed a massive temporal programming of the M. tuberculosis transcriptome.

263 ve period of early gestation when epigenetic programming of the male germline can occur, permitting t

264 Further evidence for developmental programming of the metabolic syndrome has now been sugge

265 ed that oxygen tension resulted in metabolic programming of the MSCs directing chondrogenesis into ar

266 l embedding is hypothesized to occur through programming of the neural circuitry that influences phys

267 that this ubiquitin ligase orchestrates the programming of the neural progenitors that give rise to

268 long-term effects on behavior and epigenetic programming of the NR3C1 (GLUCOCORTICOID RECEPTOR) gene

269 dds a life history perspective, arguing that programming of the offspring may in some species benefit

270 ogether, our results indicate that the early programming of the oocyte epigenome primes meiotic chrom

271 ostimulation during the later phase, but not programming of the primary CD8+ T cell response to influ

272 Programming of the primary T cell response is BCR/B cell

273 ghly vulnerable population, whereby pubertal programming of the PVN results in aberrant HPA axis resp

274 aused by LT-IH are mediated by epigenetic re-programming of the redox state in the CB chemosensory re

275 As) generated by Dicer presumably to prevent programming of the RNA-induced silencing complex (RISC).

276 loying the underlying database structure and programming of the Saccharomyces Genome Database, the Te

277 o RNA interference in eukaryotes) and the re-programming of the system to silence specific genes of i

278 e nucleotides (p)ppGpp, causing a massive re-programming of the transcriptional profile known as the

279 Re-programming of the transcriptome involves both transcrip

280 529 529 References 529 Re-programming of the transcriptome involves both transcrip

281 s under DD conditions revealed that rhythmic programming of the transcriptome is dependent on an inte

282 g how this protein leads to the selective re-programming of the translational landscape is critical.

283 p-flow intervals and independent temperature programming of the two columns, it is possible to adjust

284 ulture in vitro, this may reflect long-term "programming" of the fetal cardiovascular system.

285 murine counterpart of human asthma) through programming of their NK cells; predisposition to AAD did

286 fter experimental surgeries suggest that the programming of these characteristics follows similar rul

287 e of early life ER stress in the nutritional programming of this metabolic disease.

288 ells but are inadequate in inducing complete programming of this subset.

289 n, which is critical for sustaining temporal programming of tissue physiology.

290 e suppression through T-cell inhibition, and programming of tolerogenic macrophages.

291 oxp3 has a major role in the development and programming of Treg cells.

292 sustaining mTORC1 activation and functional programming of Treg cells.

293 both necessary and sufficient to support the programming of TRM cell fate in tissue-infiltrating T ce

294 Regulation of the programming of tumour-associated macrophages (TAMs) cont

295 vestigated the developmental and nutritional programming of uncoupling protein-2 (UCP2), glucocortico

296 of the SWNT phase allow for fast temperature programming of up to 60 degrees C/s.

297 tic receptors in primary T cells enables the programming of user-defined responses when designing T-c

298 dverse intrauterine environment alters fetal programming of vascular reactivity in adult offspring.

299 Programming of ventricular tachyarrhythmia (ventricular

300 iling, we determined sex-specific adipogenic programming of WAT progenitors isolated from pups on the