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1 ming growth factor beta receptor type II, or prolactin receptor).
2 rine system and mediated by sensory neuronal prolactin receptor.
3 binding domain in a fashion analogous to the prolactin receptor.
4 er retrovirus encoding the non-hematopoietic prolactin receptor.
5 he GHR as well as that of hGH binding to the prolactin receptor.
6  ELISA-based binding affinities with GHR and prolactin receptor.
7 , indicating transport is independent of the prolactin receptor.
8 ot only the ER but also the progesterone and prolactin receptors.
9  lymphocytes, and both B and T cells express prolactin receptors.
10  several candidate genes (cyclin D1, Stat5A, prolactin receptor) abrogates normal mammary gland devel
11 location of STAT5 can be used as a marker of prolactin receptor activation in hypothalamic dopaminerg
12  that Stat5a and Stat5b respond similarly to prolactin receptor activation, but also suggested that t
13 ome sex- and tissue-specific differences for prolactin receptor and DNA methyltransferase 3a expressi
14 sistent with functional responses, increased prolactin receptor and orexin receptor 2 expression was
15 a- and beta-cell characteristics, as well as prolactin receptor and serotonin 2B receptor expression.
16 zed acini, allowing both the exposure of the prolactin receptor and sustained activation of STAT5.
17 f matrices also increased co-localization of prolactin receptors and integrin-activated FAK, implicat
18 termini of the long (LF) or short (SF) human prolactin receptors and luciferase/GFP such that biolumi
19  kinases reportedly also are associated with prolactin receptors and may phosphorylate Stat5.
20      However, the enzymatic coupling between prolactin receptors and Stat5 in this process has not be
21 in mice have established a critical role for prolactin receptors and transcription factor Stat5 in ma
22 o the molecular mechanisms involved in human prolactin receptor antagonist (hPRL-G129R)-induced apopt
23 exes, while dopamine agonists and prolactin/ prolactin receptor antibodies may improve therapy for mi
24         Many genes that are activated by the prolactin receptor are associated with tumorigenesis and
25 dues necessary for functional binding to the prolactin receptor are clustered on the prolactin surfac
26                      We have scrutinized the prolactin receptor as an archetype model of homodimeric
27 state cancer model, we find up-regulation of prolactin receptor as cancer cells that have disseminate
28 d surface plasmon resonance to measure human prolactin receptor binding kinetics and stoichiometries
29 hese data support an "induced-fit" model for prolactin receptor binding where binding of the first re
30 xpress the short 1b form (SF1b) of the human prolactin receptor, but DU145 and PC3 cells express only
31 olecular architecture of the monomeric human prolactin receptor by combining experimental and computa
32 erated against hPRL and the ECD of the human prolactin receptor, co-immunoprecipitation analyses of h
33 e brain in PRLR(-/-) mice lacking functional prolactin receptors compared to control mice, indicating
34 acts to promote Stat5 activation by the JAK2.prolactin receptor complex, while negatively modulating
35 sis was that prolactin induced activation of prolactin receptor coupled signaling leads to increased
36 sion of angiotensin-vasopressin receptor and prolactin receptor, decreased 5 alpha-reductase, and mix
37                       Moreover, retinas from prolactin receptor-deficient mice exhibited photorespons
38                                              Prolactin receptor deletion from glutamatergic neurons o
39  IGF-2 expression restores alveologenesis in prolactin receptor(-/-) epithelium.
40 tion factor results in increased steroid and prolactin receptor expression concomitant with a 10-fold
41 dorsal root ganglia also suggested increased prolactin receptor expression in females and orexin rece
42           Additionally, we demonstrated that prolactin receptor expression in Nav1.8(+) neurons was n
43                                              Prolactin receptor expression is higher in alpha but not
44  concomitant appearance of a cell-associated prolactin receptor fragment containing the extracellular
45                                          The prolactin receptor fragment was labeled by surface bioti
46     Three promoters are operative in the rat prolactin receptor gene as follows: promoter I (PI) and
47                      The inactivation of the prolactin receptor gene by homologous recombination has
48 hat promoter III is of central importance in prolactin receptor gene transcription across species.
49 t were due to a heterozygous mutation in the prolactin receptor gene, PRLR, resulting in an amino aci
50 nscriptional activation of promoter I of the prolactin receptor gene, which may explain the tissue-sp
51 ed binding mechanism for the human prolactin/prolactin receptor heterotrimeric complex.
52  binds the extracellular domain of the human prolactin receptor (hPRLbp) using surface plasmon resona
53               Estradiol (E(2)) induces human prolactin receptor (hPRLR) gene expression through stimu
54 have identified a novel exon 11 of the human prolactin receptor (hPRLR) gene that is distinct from it
55 a-estradiol (E2)-induced activation of human prolactin receptor (hPRLR) gene transcription.
56  To determine why, we explored the human PRL-prolactin receptor (hPRLR)-Janus kinase 2 (JAK2)-signal
57 f a similar mechanism was at play with human prolactin receptor (hPRLr).
58 growth hormone receptor (hGHR) and the human prolactin receptor (hPRLR).
59 gand on the endogenous "long" isoform of the prolactin receptor in breast cancer cells.
60 the expression of the long form of the human prolactin receptor in fetal, prepubertal, and adult pros
61                        Ectopic expression of prolactin receptor in mouse cancer cells enhances microm
62       On the basis of high expression of the prolactin receptor in the choroid plexus, it has been hy
63 itary hormone, prolactin, acting through the prolactin receptor in the VMN to control the intensity o
64                                  Deletion of prolactin receptor in trigeminal ganglia by nasal cluste
65 at signal transduction mechanisms coupled to prolactin receptors in hypothalamic dopaminergic neurons
66        Indeed, ovine prolactin activated the prolactin receptors in most subpopulations of hypothalam
67  is the first indication of a role for short prolactin receptors in the regulation of cell proliferat
68      In this model, the expression levels of prolactin receptors in the retina were upregulated.
69 is study, we have analyzed the expression of prolactin receptors, including the long receptor form (L
70 uclear translocation of STAT5 as a marker of prolactin receptor induced signaling and expression of F
71                               In particular, prolactin receptor internalization and localization was
72                                          The prolactin receptor is an archetype member of the class I
73             We show that in 2D cultures, the prolactin receptor is basolaterally localized and physic
74 to assess the extent to which the absence of prolactin receptor is limiting, under systemic condition
75                        Overexpression of the prolactin receptor is seen in more than 95% of human bre
76                        The expression of the prolactin receptor is under the control of two putative
77 hort palindromic repeats-Cas9 targeting both prolactin receptor isoforms prevented stress-induced pri
78        Prolactin acts at both long and short prolactin receptor isoforms that are expressed in trigem
79 geminal nociceptors through dysregulation of prolactin receptor isoforms.
80                                              Prolactin receptor knockout females are infertile due to
81 esult from systemic endocrine alterations in prolactin receptor knockout mice, mammary epithelium fro
82                        During pregnancy, the prolactin receptor knockout transplants showed normal si
83 eptor knockout mice, mammary epithelium from prolactin receptor knockouts was transplanted into mamma
84 tion was associated with reductions in islet prolactin receptor levels, STAT5 nuclear localization an
85 oming peptides as a mimic peptide of natural prolactin receptor ligands.
86                           PRL signals at the prolactin receptor long (PRLR-L) and short (PRLR-S) isof
87 in resulting in trigeminal downregulation of prolactin receptor long and pain responses to a normally
88  Repeated restraint stress downregulated the prolactin receptor long isoform in the trigeminal gangli
89              Following downregulation of the prolactin receptor long isoform, prolactin signalling at
90                 In knockout mice lacking the prolactin receptor, mammary development is normal up to
91       The aim of this study was to correlate prolactin receptor mediated signaling and prolactin indu
92       Human prolactin (hPRL) binds two human prolactin receptor molecules, creating active heterotrim
93                                    IGF-2 and prolactin receptor mRNAs colocalize in the mammary epith
94 xample, monogenic disorders of prolactin and prolactin receptor mutations, maternal obesity and diabe
95  investigate whether increased expression of prolactin receptor (PRL-R) during lactation is caused by
96 l mutation that uncouples signaling from the prolactin receptor (PRL-R) to its downstream mediator St
97              Candidate oncogenes include the prolactin receptor PRLR activated by a focal deletion th
98 male mice in the presence and absence of the prolactin receptor (PRLR(-/-)).
99 isomerization in the interaction between the prolactin receptor (PRLR) and 14-3-3.
100 in and placental lactogen signal through the prolactin receptor (PRLR) and contribute to adaptive bet
101 ), is significantly reduced due to decreased prolactin receptor (Prlr) and ErbB4 expression in Xbp1-d
102 comes by activating their cognate receptors, prolactin receptor (PrlR) and erythropoietin receptor (E
103  show that CN/Nfatc1 regulates expression of prolactin receptor (Prlr) and that canonical activation
104 e examined the specific contributions of the prolactin receptor (PrlR) and the signal transducers and
105  mice, Ladyman and colleagues identified the prolactin receptor (Prlr) as a thermal switch lowering m
106 cently showed that a retrovirally transduced prolactin receptor (PrlR) efficiently supports the diffe
107                        Here, deletion of the prolactin receptor (Prlr) from forebrain neurons or arcu
108            Growth hormone receptor (GHR) and prolactin receptor (PRLR) in jawed vertebrates were thou
109 hat prolactin (PRL) signaling at its cognate prolactin receptor (PRLR) in primary afferents promotes
110                                    Since the prolactin receptor (Prlr) is regulated by reproductive h
111       First, using c-fos immunoreactivity in prolactin receptor (Prlr) Prlr-IRES-Cre-tdtomato reporte
112                  The short form (S1b) of the prolactin receptor (PRLR) silences prolactin-induced act
113 induce the oncogenic activation of the human prolactin receptor (PRLR) was examined by deleting 178 a
114 led that >98% of ovarian cancers express the prolactin receptor (PRLR), forming the basis of a new mo
115                                          The prolactin receptor (PRLR), its associated Janus kinase 2
116  phosphoinositides has been reported for the prolactin receptor (PRLR), the role of lipids in PRLR si
117    Prolactinomas develop in mice lacking the prolactin receptor (PRLR), which is a member of the cyto
118 e prolactin and downstream activation of the prolactin receptor (Prlr)-Jak-Stat5 pathway.
119 es, including progenitors that expressed the prolactin receptor (PRLR).
120 result of ligand-induced dimerization of the prolactin receptor (PRLr).
121  other cytokine receptors: IL-4R, IL-9R, and prolactin receptor (PRLR).
122 n neuroblastoma SH-SY5Y cells, we employed a prolactin receptor (PrlR)/erythropoietin receptor (EpoR)
123                                              Prolactin receptors (PRLr) expressed in a majority of br
124        We found that MPOA neurons expressing prolactin receptors (Prlr) form the nexus of a complex p
125 emale mice, and that conditional deletion of prolactin receptors (Prlr) from either most forebrain ne
126                     As these neurons express prolactin receptors (Prlr), prolactin may regulate GABA
127 ng through hepatocyte-predominant short-form prolactin receptors (PRLR-S), constrained TNF receptor-a
128 f tissue-resident macrophages, expresses the prolactin-receptor (PRLR).
129                                              Prolactin receptors (PRLRs) are widely expressed, and mu
130 istribution and ontogenesis of expression of prolactin receptors (PRLRs) in human fetal tissues at 7.
131 igh-affinity ligand-binding interface of the prolactin receptor, resulting in a loss of downstream si
132                            Assessment of the prolactin receptor reveal relatively high abundance acro
133 rolactin, a lactogenic hormone, binds to two prolactin receptors sequentially, the first receptor bin
134 or long isoform, prolactin signalling at the prolactin receptor short isoform sensitizes nociceptors
135 ultiple human cancers, COX-2, prolactin, and prolactin receptor show consistent differential expressi
136 d OAS expression may result in modulation of prolactin receptor signaling and thus contribute to supp
137  correlated with the luteal induction of the prolactin receptor signaling inhibitors suppressor of cy
138                                   Functional prolactin receptor signaling was further demonstrated in
139 st cancer progression and therapy as loss of prolactin receptor-Stat5 signaling occurs frequently and
140 nuate the activity of the hGHR and the human prolactin receptor, suggesting that this peptide acts as
141  Members of the cytokine/growth hormone (GH)/prolactin receptor superfamily transduce signals by asso
142 ellular or intracellular domains enabled the prolactin receptor to copatch with EpoR.
143 h impaired intercellular junction formation, prolactin receptor trafficking, and alveolar lumen devel
144 Quantification of differential expression of prolactin receptor variants by real-time PCR in 15 pairs
145          Both the long and short form of the prolactin receptor was expressed, yet only the long isof
146                        Since the presence of prolactin receptors was earlier demonstrated in hypothal
147    Using a novel conditional deletion of the prolactin receptor, we have identified functional subpop
148 tinal polypeptide, purinergic, androgen, and prolactin receptors were also expressed in gland of Wolf
149            Kisspeptin neurons, which express prolactin receptors, were recently identified as major r
150 in barrier, was examined for the presence of prolactin receptors, which would render it a potential s

 
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