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2 as required to define the transition between proliferating and arrested cells inside the LRP, coincid
5 s indicate HepaRG is a useful model to study proliferating and differentiated cell mitochondrial toxi
7 but, on average, the likelihood of producing proliferating and differentiating cells is equal, ensuri
9 AV challenge and assessed the percentages of proliferating and IAV-infected, alveolar type II (AECII)
10 son is that the dynamic relationship between proliferating and necrotic cell populations during vascu
11 s to CTLA-4 and PD-1 reversed HIV latency in proliferating and nonproliferating CD4(+) T cells, respe
13 ing a 24 h period, revealing the fraction of proliferating and promigratory/proinvasive cells present
15 ide insight into proteasome dynamics between proliferating and quiescent yeast in response to cellula
17 lls responded to SIV/simian HIV infection by proliferating and upregulating alpha4beta7, coinciding w
18 LI1 inhibitor), was substantially reduced in proliferating and, to a lesser extent, lineage-committed
19 ound to express DR3 and responded to TL1A by proliferating and/or producing fibrotic molecules such a
20 We show that CLEC3A is present in resting, proliferating, and hypertrophic growth-plate cartilage a
21 spond to damage by disassembling sarcomeres, proliferating, and repopulating the injured area remain
22 zing the gene-expression profile of actively proliferating aneuploid cells to that of euploid cells g
25 he model eukaryote Saccharomyces cerevisiae, proliferating at different growth rates, and differentia
26 e we report that GCBCs are exceptional among proliferating B and T cells, as they actively oxidize fa
27 anding of how after EBV primo-infection, EBV-proliferating B cells can survive in an aggressive immun
28 are confined anatomic regions where rapidly proliferating B cells undergo somatic mutation and selec
29 on in digested lymphoid tissues, clusters of proliferating B cells with a GC-like phenotype can be ge
30 f1a(+) lineage beta-cells had fewer Ki-67(+) proliferating beta-cells, and expressed higher mRNA leve
31 r adult zebrafish tailfins is encoded within proliferating blastema cells during a critical period of
34 chondria allow for the opportunity to poison proliferating cancer cell mtDNA replication as certain c
35 stic of many human tumors, providing rapidly proliferating cancer cells with metabolites that can be
43 bition results in tumour shrinkage in highly proliferating CCND1-driven PDX, including different RB-p
44 ib run-in was associated with an increase in proliferating CD4(+) T-helper cells but not with an incr
46 acid significantly expands the proportion of proliferating CD8(+) T cells in the tumor with enhanced
47 elonging to the TEOSINTE BRANCHED1/CYCLOIDEA/PROLIFERATING CELL FACTOR (TCP) protein family are known
48 we report that teosinte branched1/cycloidea/proliferating cell factor1-20 (TCP20) and NIN-like prote
49 l nervous system (CNS)-derived conditionally proliferating cell line that can be differentiated into
50 pproach that leverages error-prone PCR and a proliferating cell model to identify such gain-of-functi
54 th muscle mass, paired box protein 7 (Pax7), proliferating cell nuclear antigen (PCNA) and nicotinami
55 through its interactions with two proteins, Proliferating Cell Nuclear Antigen (PCNA) and Replicatio
57 replication factor C (RFC) and sliding clamp proliferating cell nuclear antigen (PCNA) are both essen
59 In human cells, the DNA replication factor proliferating cell nuclear antigen (PCNA) can be conjuga
60 n multiple transient events in the reaction: proliferating cell nuclear antigen (PCNA) clamp binding/
61 s a mismatch, MutSalpha/beta, and DNA-loaded proliferating cell nuclear antigen (PCNA) for activation
62 plication forks through its interaction with proliferating cell nuclear antigen (PCNA) for nucleosome
64 ily TLS polymerases to damaged DNA relies on proliferating cell nuclear antigen (PCNA) monoubiquityla
65 loading of cyclin-dependent kinase (CDK) and proliferating cell nuclear antigen (PCNA) onto chromatin
67 NA polymerase delta (Pol delta) bound to the proliferating cell nuclear antigen (PCNA) replicates the
68 TLS requires selective monoubiquitination of proliferating cell nuclear antigen (PCNA) sliding clamps
69 eration in calcified arteries as assessed by proliferating cell nuclear antigen (PCNA) staining was a
70 ective bioPROTAC against an oncology target, proliferating cell nuclear antigen (PCNA) to elicit rapi
71 ly, we found that AKT-mediated modulation of Proliferating Cell Nuclear Antigen (PCNA) ubiquitylation
72 cleotide by DNA polymerase alpha holoenzyme, proliferating cell nuclear antigen (PCNA), a homotrimeri
74 entry is similar to that described for human proliferating cell nuclear antigen (PCNA), a small ubiqu
75 Y-family polymerases, Poliota interacts with proliferating cell nuclear antigen (PCNA), Rev1, ubiquit
76 ammatory cytokines, the proliferation marker proliferating cell nuclear antigen (PCNA), the anti-infl
77 A We show that Rad51 inhibits recruitment of proliferating cell nuclear antigen (PCNA), the platform
79 the density of mitotic figures, and BrdU and proliferating cell nuclear antigen (PCNA)-reactive cells
86 ersely, nascent DNA replication foci and the proliferating cell nuclear antigen(PCNA) protein have a
87 tethers it to the leading strand, and PCNA (proliferating cell nuclear antigen) binds tightly to Pol
88 olution dynamics of the human clamp protein, proliferating cell nuclear antigen, by monitoring the ch
89 and expression of the proliferation marker, proliferating cell nuclear antigen, indicative of intest
90 synthesis as essential for cccDNA formation: proliferating cell nuclear antigen, the replication fact
91 ll microscopy of cells harboring fluorescent proliferating cell nuclear antigen, we confirmed that 8a
92 (MMP) 9-, and MMP13-positive cells and more proliferating cell nuclear antigen- and pSMAD5-positive
93 these tissues contain a small proportion of proliferating cells (assessed by both Ki67 and PCNA) but
97 ineages showed a reduction in populations of proliferating cells and intermediate cells, and overall
98 ered every 3 days to determine the number of proliferating cells and the number of newly maturing neu
99 colony physically constrains the packing of proliferating cells and, thus, controls colony shape.
102 that methylation of newly synthesized DNA in proliferating cells can be altered by oxidants that targ
103 ited reduced cell density and fewer actively proliferating cells compared to the control and bexarote
105 e concurrent with myocardial infiltration of proliferating cells displaying a poorly differentiated m
107 al precursor cells that can be maintained as proliferating cells due to the expression of a tetracycl
108 (ADC) distinguishes meningioma regions with proliferating cells enriched for developmental gene expr
109 iferating human CD4(+) T cells, we show that proliferating cells express multiple IC molecules at hig
115 nals control keratinocyte differentiation in proliferating cells independently of actual DNA damage.
116 ll orders of life, cell cycle progression in proliferating cells is dependent on cell growth, and the
118 YAP and WPB2 are upregulated in actively proliferating cells of mouse and human epidermis and cSC
120 t DC cells are recent progeny of selectively proliferating cells present prior to morphogenesis and t
124 likely to arrest than to die, whereas slowly proliferating cells showed a higher probability of death
127 vulnerability of proteostasis maintenance in proliferating cells that may be compromised by diverse g
128 n program, which culminates in immortalized, proliferating cells that partially resemble plasmablasts
130 es, and the resolution of SEs in mitotically proliferating cells via SCML2, a germline-specific Polyc
132 to the nucleus and endogenously expressed in proliferating cells whereas p22(CBX7) was localized to t
133 sponses to cisplatin and suggest that slowly proliferating cells within tumors may be acutely vulnera
136 to be completely reprogrammed to support the proliferating cells, but 3 additional clusters of EBV-re
139 tional compensation is most prominent in non-proliferating cells, clearly delineating two temporally
142 zyme and appears on the surface of cancerous proliferating cells, has been used as a diagnostic bioma
144 ent state of replicative arrest in otherwise proliferating cells, is a hallmark of aging and has been
145 s chromatin patterns are being duplicated in proliferating cells, predisposing them to tumorigenesis.
146 In contrast to the role of nuclear RNF8 in proliferating cells, RNF8 operates in the cytoplasm in n
161 ceptor, which is abundantly expressed in the proliferating cerebellar granule cell progenitors, regul
163 hat delineates a human Tfh helper program in proliferating circulating Tfh (cTfh) cells and Germinal
164 ificity, and detects extramedullary sites of proliferating clonal plasma cells while providing import
166 cRNA interacting with SMARCB1 exclusively in proliferating conditions, exerting a pro-oncogenic role
167 n disintegrates, or, alternatively, it keeps proliferating, contributing heavily to the population of
170 able to follow sublineages that emerged from proliferating CTB at the periphery of the conceptus.
171 e single-cell measurements of p21 protein in proliferating cultures, we show that naturally occurring
172 tain their numbers through a pool of locally proliferating CX(3)CR1(-) mononuclear cells that are emb
174 mechanism of inherited drug resistance, but proliferating DIT cells can produce progeny with increas
176 the expression patterns of circular RNAs in proliferating (early-passage) and senescent (late-passag
177 the female gametophyte and in the zygote and proliferating endosperm of the Arabidopsis (Arabidopsis
181 valent of the vertebrate tight junction, but proliferating follicle cells do not have mature septate
183 receptor (p75NTR) is highly expressed in the proliferating granule cell precursors (GCPs) during deve
189 g this question has been challenging because proliferating hepatocytes can increase or decrease ploid
190 iptomics, we link changes in the lipidome of proliferating hepatocytes to altered metabolic pathways
191 order to capture the metabolic signature of proliferating hepatocytes, we applied state-of-the-art s
193 hether inhibition of nucleotide synthesis in proliferating HMECs is sufficient to induce senescence.
195 blishes latency in both nonproliferating and proliferating human CD4(+) T cells, we show that prolife
196 pathways interact to maintain homeostasis in proliferating human cells, using fluorescent reporters f
197 tions (the proportion of the tumour which is proliferating, hypoxic/quiescent and necrotic/nutrient-d
203 Human insulinomas are rare, benign, slowly proliferating, insulin-producing beta cell tumors that p
205 This is consistent with fewer activated and proliferating intrarenal and splenic B cells in mice lac
211 t of host T cells in peripheral tissues were proliferating (Ki67+) and producing the proinflammatory
212 Treatment resulted in transient increases in proliferating (Ki67+) natural killer and CD8 T cells.
215 vivo, they are transformed into continuously proliferating lymphoblastoid cell lines (LCLs) that carr
216 iomimetic nanoparticles showed a decrease in proliferating macrophage population that was accompanied
217 ver, we have found that a high proportion of proliferating macrophages in human tumors express ERK5.
218 f disaggregated aortic tissue revealed fewer proliferating macrophages in the aorta (15.6+/-9.79 %) c
222 resses the reprogramming of Muller glia into proliferating MGPCs and this 'hub' coordinates signals p
224 s of mitochondrial dysfunction to the ISR in proliferating mouse myoblasts and in differentiated myot
229 in the first weeks of infection, for example proliferating natural killer cells, which potentially ma
231 significantly altered, 2) the population of proliferating neural progenitors in the SVZ was reduced,
232 ganoids are smaller with a reduced number of proliferating neuronal progenitors while mutant ugdh zeb
235 ork reveals previously unknown ways in which proliferating NG2(+) cells contribute to endogenous repa
238 After infusion of Cy, a marked reduction of proliferating NK cells was evident, suggesting selective
240 n treatment reduced the density of total and proliferating Nkx2.1(+) and Dlx2(+) cells in the MGEs an
242 igher populations of residing granule cells, proliferating NSCs and BrdU+ neurons in the dDG, whereas
243 cluster significantly reduced the number of proliferating NSCs and neuroblasts and neuronal differen
244 ing oligodendrocytes and with a reduction in proliferating oligodendrocyte progenitor cells (OPCs).
245 d insulin sensitivity were assessed in human proliferating or adipocyte-differentiated adipose stem c
250 bumin, became prematurely accumulated at the proliferating phase of seed development in the e2fab dou
251 Cs), characterized by three distinct stages: proliferating phase, involuting phase, and involuted pha
252 P+) was decreased in SNCA-A30P mice, whereas proliferating (phospho-histone 3+) cells were decreased
253 changes that occur during the maturation of proliferating plasmablast to quiescent plasma cell under
255 ell-sorting behaviors, cell intercalation in proliferating populations, and the involution of germ la
256 hogenic cells were mitotically inactive, but proliferating precursors were detected in primary cultur
257 from HS patients had an increased number of proliferating progenitor cells and lost quiescent stem c
258 ing cancer stem cells that give rise to fast-proliferating progenitor-like cells and to nondividing c
259 riant was deregulated, especially within the proliferating progenitors during limb regeneration.
261 irst time that squamates exhibit a source of proliferating progenitors persisting post embryogenesis
264 le by generating a 2D agent-based model of a proliferating PSE and compared its output to the growth
267 nctionally variable cohort of taxa, adept at proliferating rapidly within hosts, which gradually matu
268 ish retina contains a population of actively proliferating resident stem cells, which generate retina
271 orm in injured nerves, although they contain proliferating Schwann cells with strikingly elevated c-J
273 intimal hyperplasia, PCSK6 was expressed by proliferating SMA+ cells and upregulated after 5 days in
275 n Drosophila occurs with the transition from proliferating spermatogonia to differentiating spermatoc
276 , as in other metazoan stem cells and in the proliferating stages of two unicellular holozoans, inclu
280 y, but we also discovered these mediators in proliferating T cells and natural killer T cells, that a
281 cially in cancer immunotherapy, where highly proliferating T cells will encounter potentially large a
282 human tumor-infiltrating lymphocytes (TIL), proliferating TILs, and in vitro differentiated neurons,
284 tor cells of embryonic human brain and other proliferating tissues, is co-expressed with components o
287 , with single or multiple budding, sometimes proliferating to form short, branching, hyphal-like elem
289 s of quiescent stem cells (SCs) give rise to proliferating transit-amplifying cells before terminal d
290 bryonic intestine transitions from a rapidly proliferating tube with pseudostratified epithelium prio
291 tubules of kidneys undergoing ACR represent proliferating tubular epithelial cells with TNFR2-induce
293 articular feature is used for targeting fast-proliferating tumor cells during chemo-, radio-, and imm
295 rs, cells transition reversibly between slow-proliferating tumor-initiating cells (TIC) and their dif
297 s hematopoietic stem cells) or which started proliferating uncontrollably (such as cancer cells).
298 ne to study ddC-induced toxicity in isogenic proliferating (undifferentiated) and nonproliferating (d