ライフサイエンスコーパス: proliferation

1 e chemokine CXCL-11, which suppressed T cell proliferation.

2 double knockout cells have major defects in proliferation.

3 d knockdowns of PYCR1 lead to decreased cell proliferation.

4 tion, and SMAD7 overexpression enhanced cell proliferation.

5 previously been linked to density-dependent proliferation.

6 cellular development, function, growth, and proliferation.

7 n of extracellular matrix proteins, and cell proliferation.

8 uced glycolysis, and ultimately reduced cell proliferation.

9 egulators of insulin secretion and beta cell proliferation.

10 ed with lower VSMC MIA3 expression and lower proliferation.

11 ELK being classified as essential for cancer proliferation.

12 ivity prevented hypoxia- and oxidant-induced proliferation.

13 tivity of cancer cells to drive unrestricted proliferation.

14 colytic ATP production and restored cellular proliferation.

15 h also induced a delay in cryptal epithelial proliferation.

16 blocks glucose-induced fibrogenesis and cell proliferation.

17 iosynthetic intermediates necessary for cell proliferation.

18 cell depletion and insufficient compensatory proliferation.

19 role in pregnancy-induced maternal beta-cell proliferation.

20 ansport and a reduction in meristematic cell proliferation.

21 t factor(s) which regulate the myeloid cells proliferation.

22 ibits IL-1beta-induced RA-FLS activation and proliferation.

23 3 significantly reduced S100A9-mediated cell proliferation.

24 nced Akt activity and increased rate of cell proliferation.

25 acts on either ERalpha binding or MCF-7 cell proliferation.

26 metabolic adaptation to sustain uncontrolled proliferation.

27 heir ability to reduce inflammation and cell proliferation.

28 ficantly attenuated RV but not LV fibroblast proliferation.

29 thesis required for anabolic cell growth and proliferation.

30 identified PI3K-delta as required for tumor proliferation.

31 vated markers of inflammatory chemokines and proliferation.

32 d to regulate inflammatory response and cell proliferation.

33 n function in vivo during periods of reduced proliferation.

34 acetylated KLF5 is known to alter epithelial proliferation.

35 lternative splicing and controls cancer cell proliferation.

36 nsitizes tumor cells to anoikis and inhibits proliferation.

37 thereby couples protein production with cell proliferation.

38 tion also induced YAP signaling and cellular proliferation.

39 ted growth but resulted in eventual adaptive proliferation.

40 ed colony formation capability and inhibited proliferation.

41 8-fold and significantly inhibited U251 cell proliferation.

42 ctivated receptor gamma activity and reduced proliferation.

43 PI3K/Akt pathway, regulating cell growth and proliferation.

44 y culture in TSC medium to maintain cellular proliferation.

45 onment needed for Y. pestis colonization and proliferation.

46 genesis, differentiation, cell migration and proliferation.

47 wed that MBNL3 and KANSL2 do not affect cell proliferation.

48 osages of Si above 100 mug/ml decreased cell proliferation.

49 ghter cells-is a key step in cell growth and proliferation.

50 on the regulation of cytokine production and proliferation.

51 The nucleolar protein block of proliferation 1 (BOP1) is associated with multiple cance

52 NKX3.1 acts by retarding proliferation, activating antioxidants, and enhancing DN

53 tor for IL-2, a cytokine important in immune proliferation, activation, and regulation.

54 Methods: Inhibition of cell proliferation after incubation of the RPMI8226 cell line

55 alization of mitochondria and decreased cell proliferation, altered expression levels of pyruvate deh

56 signaling target genes, results in decreased proliferation and altered jaw skeletal differentiation a

57 NF-kappaB pathway and elevated expression of proliferation and anti-apoptosis genes such as BCL2L1 an

58 In addition, we observe differences in proliferation and apoptosis as well as altered distribut

59 nvestigated the effects of IL2RA on AML cell proliferation and apoptosis, and on pertinent signaling

60 ithelial cells kept their original levels of proliferation and apoptosis.

61 7 as a novel regulator of mammary epithelial proliferation and breast cancer pathogenesis likely via

62 ility in vitro severely inhibited CD4 T cell proliferation and cell cycle progression.

63 a cells and counteracts the decrease in cell proliferation and colony formation caused by UV-induced

64 rentiation towards beta-catenin, a driver of proliferation and colorectal tumorigenesis.

65 how low levels of Beclin 1 facilitate tumor proliferation and contribute to poor cancer outcomes.

66 rom human tissue, stimulated HDAC3-dependent proliferation and countered butyrate inhibition of colon

67 which on further study demonstrated reduced proliferation and delayed differentiation compared with

68 e that type III IFNs disrupt epithelial cell proliferation and differentiation in the lung.

69 rostate development depends on balanced cell proliferation and differentiation, and acetylated KLF5 i

70 multiple genes, including some with roles in proliferation and differentiation, and in IGF and TGFbet

71 ency, and function, particularly in cellular proliferation and differentiation, as well as in systemi

72 l, radial glia-like neural stem cells (NSCs) proliferation and differentiation, migration, and matura

73 ibit skeletal size by repressing chondrocyte proliferation and differentiation.

74 important epigenetic reader involved in cell proliferation and differentiation.

75 associated increases in prostate cancer cell proliferation and disease progression.

76 n synthesis signatures; these CTCs expressed proliferation and epithelial markers and correlated with

77 mplicate Gal-9 in the regulation of cellular proliferation and epithelial restitution after intestina

78 ckpoint inhibitor treatment increased T cell proliferation and functionality, but its influence on th

79 s through the induction of genes involved in proliferation and glycolytic metabolism.

80 found an unexpected abundance of chemotropic proliferation and guidance cues that are commonly implic

81 of monounsaturated PC with hallmarks of cell proliferation and hepatic carcinogenesis.

82 negative individuals show markedly increased proliferation and higher reticulocyte yields, suggesting

83 Cell proliferation and immune activity pathways were enriched

84 zed DCN expression to areas of microvascular proliferation and immunohistochemical studies localized

85 hearts, and markedly enhances cardiomyocyte proliferation and improves cardiac function in infarcted

86 Although reduced proliferation and increased apoptosis were observed in a

87 arkers of inflammation, DNA damage, and cell proliferation and increases colorectal tumorigenesis in

88 temozolomide, significantly reduces cellular proliferation and increases DNA damage.

89 PFBS exposure interrupted cell proliferation and invasion in a dose-dependent manner.

90 ficacy of ICT12035, in a number of 2D and 3D proliferation and invasion in vitro assays and an in viv

91 HF19 in controlling the balance between cell proliferation and invasiveness in prostate cancer.

92 s a variety of cellular processes, including proliferation and metabolism.

93 rc/YAP axis as a key player in promoting the proliferation and migration of ECs that are critical in

94 ellate cell activation, which then decreased proliferation and migration of tumor cells in different

95 zones provide a platform for progenitor cell proliferation and migration.

96 nt depletion and the resulting inhibition of proliferation and motility of bacteria and phages are th

97 n perturbs adherens junctions, enhances cell proliferation and motility, and decreases dependence on

98 at these genes reduce neural progenitor cell proliferation and neurite growth.

99 ysis suggested that pathways associated with proliferation and nutrient sensing are modulated by metf

100 The Hippo pathway regulates cell proliferation and organ size through control of the tran

101 use lymphocytic leukemia cells during normal proliferation and polyploidization.

102 Cell proliferation and quiescence are intimately coordinated

103 ts genetic silencing increases melanoma cell proliferation and reduces cell death.

104 on state that correlated with their enhanced proliferation and resistance to radiation therapy.

105 idkine-a, resulting in significantly reduced proliferation and selective failure to regenerate cone p

106 ncer cell lines mediated changes in cellular proliferation and sensitivity to cisplatin.

107 clade G1, exCNLs have evolved through recent proliferation and sequence diversification.

108 polyploidy poses a barrier for cardiomyocyte proliferation and subsequent heart regeneration.

109 nt regulation of CF transdifferentiation and proliferation and suggest that PKC agonists exhibit pote

110 bition furthermore selectively decreases the proliferation and survival of ABC-DLBCL in vitro and inh

111 mediated functional ABCB5 blockade inhibited proliferation and survival of GBM cells and sensitized t

112 th mTORC1 and mTORC2 signals to promote cell proliferation and survival, but also induced an AKT-depe

113 tment with corticosteroid allows for initial proliferation and sustained M. abscessus pulmonary infec

114 Taken together, rapamycin attenuated PEC proliferation and the formation of early FSGS lesions in

115 marks and enablers of cancer, including cell proliferation and the response to DNA damage.

116 s, the effect of these nanoparticles on cell proliferation and toxicity was evaluated, which clearly

117 ted from mice with DED directly promoted VEC proliferation and tube formation compared with normal co

118 c processes that contribute to aberrant cell proliferation and tumorigenesis.

119 unforeseen role of GLS2 in sustaining tumor proliferation and underlying metastasis in breast cancer

120 showing that the inferred mechanisms of anti-proliferation and/or cell-killing are consistent with th

121 alters their reactive status, and attenuates proliferation and/or infiltration of microglia to the re

122 cterize active (endocapillary-extracapillary proliferations) and chronic (tubulo-interstitial) renal

123 Cell viability, proliferation, and cell cycle were evaluated by the MTS

124 associated with increased BCR signaling, CLL proliferation, and clonal evolution.

125 (Tgr5(ISC-/-) mice) and analyzed ISC number, proliferation, and differentiation by flow cytometry, im

126 c precursors and promote their self-renewal, proliferation, and differentiation.

127 e regulation as cells navigate their growth, proliferation, and differentiation.

128 (PDGFR)-alpha plays roles in cell survival, proliferation, and differentiation; however, its functio

129 macologically and genetically activated cell proliferation, and HCC.

130 enhanced overall MCM2 levels, promoted cell proliferation, and improved the synergistic cytotoxicity

131 r diverse roles in oncogenic transformation, proliferation, and metastasis.

132 elevant phenotypes related to calcification, proliferation, and migration in VSMCs isolated from 151

133 results in increased myocardial survival and proliferation, and overall heart regeneration, accompani

134 m alters cell behavior, including migration, proliferation, and paracrine activity, which are essenti

135 hat promote cardiomyocyte dedifferentiation, proliferation, and protrusion into the injured area.

136 Loss of SMAD7 in beta cells inhibited proliferation, and SMAD7 overexpression enhanced cell pr

137 KO cells restores proline synthesis and cell proliferation, and suppresses DRP1 expression and mitoch

138 n swine arteries, the BEM increases cellular proliferation, angiogenesis, and connective tissue depos

139 Their importance in proliferation, apoptosis, and cell death ultimately rend

140 TMZ alone, and combined experiments of cell proliferation, apoptosis, wound healing assay, as well a

141 d upregulation of genes associated with cell proliferation as compared to liposomes alone.

142 leishmanial drugs inhibit CD4 and CD8 T cell proliferation at the doses that are not related to incre

143 eyes with ORHR and ORNV at baseline, pigment proliferation became visible in 4 eyes.

144 ction of eicosanoids, acting to promote cell proliferation beyond a cell-autonomous manner.

145 usly we showed that YAP/TAZ promote not only proliferation but also differentiation of immature Schwa

146 SMI#9 treatment inhibited melanoma cell proliferation but not normal melanocytes.

147 or Tsc2 leads to metabolic re-initiation and proliferation, but at the expense of incurring substanti

148 ular organisms use mitogens to regulate cell proliferation, but how fluctuating mitogenic signals are

149 STAT6 did not enhance intracellular parasite proliferation, but rather modulated the size and permiss

150 pansion does not involve an increase in cell proliferation, but rather results from re-specification

151 n chicken utricles and promoted regenerative proliferation, but YAP remained cytoplasmic and little p

152 r, chromatin remodeling, apoptosis, and cell proliferation; but it remains unclear whether variants i

153 nd RepoMan independently promote cancer cell proliferation by reducing checkpoint--induced cell-cycle

154 h other pathways implicated in cardiomyocyte proliferation calls for the identification of nodal poin

155 s in the cell signaling before cardiomyocyte proliferation can be moved forward toward clinical appli

156 tology and ex vivo assessments of urothelial proliferation, cell cycle, and ploidy status.

157 tiation without significantly affecting cell proliferation, cell death, or UPR induction in murine my

158 kdown of GDH1 significantly reduced the cell proliferation, colony formation and tumorigenesis abilit

159 EMA4C promotes adhesion and reduces cellular proliferation, colony formation, migration, wound healin

160 letion of PTEN and/or PTENP1 increased DU145 proliferation compared to non-targeting siRNA, which was

161 ng endothelial cell and alveolar type 2 cell proliferation.Conclusions: Postnatal rhIGF-1/BP3 treatme

162 ic metabolic changes that direct activation, proliferation, cytotoxic function, and epigenetic change

163 TP levels, while exogenous dNTPs rescues the proliferation defect induced by lincNMR depletion.

164 ously inhibits the STAT3-induced cancer cell proliferation, demonstrating a novel approach in cancer

165 provide clonal-level insights into cellular proliferation, development, differentiation, migration,

166 the DDR is required to maintain the balance proliferation differentiation and suggest that is part o

167 epigenetic factor, participates in cellular proliferation, differentiation, and death.

168 es many highly regulated processes including proliferation, differentiation, and maturation.

169 regulate signaling pathways controlling cell proliferation, differentiation, and survival.

170 loping human brain, likely arising from cell proliferation during mid-neurogenesis.

171 lls in mosaic embryos undertake compensatory proliferation during the implantation stages to confer e

172 t prolonging the half-life of Nkx3.1 reduces proliferation, enhances DNA end-labeling, and protects f

173 Interestingly, MNT was required for cell proliferation even in the absence of MAX.

174 rolysis restores NAD(+)/NADH homeostasis and proliferation even when glucose oxidation is increased.

175 ited much stronger Ag-specific CD4(+) T cell proliferation ex vivo.

176 candidate (miR-216a) implicated in beta cell proliferation for subsequent validation by RT-PCR.

177 at ATG5-dependent autophagy uncouples T-cell proliferation from its effector functions and offers a p

178 amic cytodifferentiation, body-axis and cell-proliferation gene sets that were further characterized

179 for dnmt1 activity in the regulation of RSC proliferation, gene expression and in the repression of

180 acuity, and presence of retinal angiomatous proliferation had a higher risk of greater MA progressio

181 en receptor (CAR) T-cell biodistribution and proliferation harbor the potential to facilitate clinica

182 ntribute to behavior later in life when cell proliferation has slowed.

183 creased expression of genes involved in cell proliferation, immune responses, and cholesterol biosynt

184 entify mechanisms of tumor cell survival and proliferation in adherent and nonadherent cells.

185 tion of Cdk1 is an early driver of cyst cell proliferation in ADPKD due to Pkd1 inactivation.

186 The genes required for survival and proliferation in blood have not been identified.

187 and PVL+DMOG accelerated liver growth and HC proliferation in comparison to PVL.

188 NRG1 robustly stimulates proliferation in crypts and induces budding in organoids

189 n bands, depletes E-cadherin, and stimulates proliferation in long-quiescent supporting cells within

190 inal neovascularization and endothelial cell proliferation in OIR.

191 own of HB-EGF in rat islets blocks beta-cell proliferation in response to glucose ex vivo and in vivo

192 depleting CDK4 and 6 was sufficient to limit proliferation in specific resistance settings, RB loss r

193 regulation of PTEN and increase in beta cell proliferation in that group.

194 uired for increased neural stem cell and OPC proliferation in the adult mouse SVZ following demyelina

195 en five distinctive body plans, with asexual proliferation in the snail host and sexual proliferation

196 l proliferation in the snail host and sexual proliferation in the vertebrate host, and motile free-li

197 he Wnt signaling pathway triggers human BTSC proliferation in vitro and influences PBG hyperplasia in

198 Depletion of SFMBT1 abolished ccRCC cell proliferation in vitro and inhibited orthotopic tumor gr

199 tic high molecular weight HA promoted HPASMC proliferation in vitro, whereas pharmacologic inhibition

200 s in experimental FSGS and reduced human PEC proliferation in vitro.

201 ch PMNs directly induce tumor cell death and proliferation in vivo and suggest that the contrasting p

202 plication of neonicotinoids has led to their proliferation in waters.

203 d silencing of TMPRSS13 expression decreases proliferation, induces apoptosis, and attenuates invasio

204 protection is accompanied by decreased cell proliferation, inflammation, steroid biosynthesis, neutr

205 ly, IL-12 and anti-IL-10 Abs improved T cell proliferation inhibited by AmB.

206 Selective targeting of cyst cell proliferation is an effective means of slowing ADPKD pro

207 brosis, lymphocytic infiltrates and ductular proliferation, lobular cholestasis, and acute liver cell

208 Fibrocellular retrocorneal membrane proliferation may be associated with DSAEK failure in pa

209 n the bile duct, including ductal epithelial proliferation, micropapillary growth of biliary epitheli

210 T), a metabolite known to influence cellular proliferation, migration, and angiogenesis.

211 utero developmental processes such as neural proliferation, migration, and differentiation.

212 ptor (IGF1R) signaling promotes keratinocyte proliferation, migration, and survival.

213 ogression, and metastasis by regulating cell proliferation, migration, invasion, drug resistance, and

214 gulate c-MYC and directly inhibit tumor cell proliferation, NHWD-870 blocks the proliferation of tumo

215 fundamental requirements for cell growth and proliferation, nitrogen acquisition and utilization must

216 ion, but YAP remained cytoplasmic and little proliferation occurred in mouse utricles.

217 akes in Wisconsin following the invasion and proliferation of a novel predator (spiny waterflea, Byth

218 , the interaction inhibits the autocatalytic proliferation of amyloid fibrils by secondary nucleation

219 rtrophy (POH) to HFpEF is the activation and proliferation of an abnormal fibroblast phenotype that i

220 DAC cells revealed that older NHFs stimulate proliferation of and confer resistance to radiation ther

221 ) is a multipotent cytokine that prompts the proliferation of bone marrow-derived macrophages and gra

222 IL-10, TGF-beta and GITR; P < 0.05), and the proliferation of both Treg and Th17 cells in cervical ly

223 ), that is sufficient to enable survival and proliferation of CI mutant cells under nutrient stress c

224 The exponential proliferation of data during the information age has req

225 ndured bleaching, and then recovered through proliferation of heat-tolerant symbionts.

226 Hence, with the proliferation of high-throughput assay technology, there

227 The inhibition of RUNX1 reduced proliferation of human C-PVR cells in vitro, and curbed

228 Proliferation of intestinal stem cells in MCL1-deficient

229 barrier to curing HIV infection, the in vivo proliferation of latently infected cells.

230 t of DMOG-treated HSC induced VEGF-dependent proliferation of LSEC.

231 ocyte antigen risk alleles, and drug-induced proliferation of lymphocytes isolated from patients supp

232 tudy, we have shown that TRIM21 enhances the proliferation of MCF7 breast carcinoma cells and counter

233 production and was associated with a higher proliferation of memory Tregs.

234 bility, but also enhanced the attachment and proliferation of MSCs.

235 Notch signaling controls proliferation of multipotent pancreatic progenitor cells

236 n of SREBP1 significantly inhibited the cell proliferation of mutant KRAS-expressing cells.

237 ni-protein is cell permeable and can inhibit proliferation of Myc-dependent cell lines.

238 -glutamate conversion preferentially blocked proliferation of N-Myc overexpressing cells, when glutam

239 wed that B. miyamotoi-stimulated DCs induced proliferation of naive CD4(+) and CD8(+) T cells to a la

240 s an essential cytokine for the survival and proliferation of natural killer (NK) cells.

241 he dentate gyrus, which was due to inhibited proliferation of neural stem cells (NSCs).

242 The rapid proliferation of new synthetic cannabinoid receptor agon

243 Although proliferation of NSCs and neurogenesis seen in Ccn1 knoc

244 es vascular volume and blood flow, increased proliferation of PCs and ECs, and attenuated loud sound-

245 cy, G6PD knockout did not block formation or proliferation of primary lung tumors.

246 Rejection was associated with proliferation of recipient CD8 T effector cells in the p

247 However, when proliferation of resident epithelial cells is impaired,

248 ibitor) attenuated colony formation and cell proliferation of skin cancer cells.

249 Solenopsins also reduced the intracellular proliferation of T. cruzi amastigotes in infected macrop

250 n does not affect cell cycle progression and proliferation of the cancer cells tested, the novel subs

251 ased in DD tissues, suggesting opportunistic proliferation of these taxa.

252 st to studies with peripheral NKT cells, the proliferation of thymic NKT cells was significantly impa

253 s that CSF-1 is involved in the survival and proliferation of trophoblast cells in EP.

254 fter acute kidney injury (AKI) with adaptive proliferation of tubular epithelial cells, but repair ca

255 umor cell proliferation, NHWD-870 blocks the proliferation of tumor associated macrophages (TAMs) thr

256 Finally, 45 inhibited proliferation of two cancer cell lines that are resistan

257 parameters, such as the rate of tumour cell proliferation or sensitivity to hypoxia, can produce sph

258 ion there were no detectable effects on cell proliferation or viability.

259 However, the role of autophagy in epidermal proliferation, particularly under conditions when the ep

260 or tyrosine kinase (RTK) and JAK-STAT-driven proliferation pathways 'parallel' or 'redundant'?

261 'Parallel' proliferation pathways accomplish a similar drug resista

262 ing mutations, with chromatin remodeling and proliferation pathways altered primarily by coding mutat

263 otic enhancers in the somatic and/or mitotic proliferation phases.

264 Retrotransposon proliferation poses a threat to germline integrity.

265 Further, the proliferation potential of GMSCs was greater than PDLMSC

266 s to identify molecules to promote beta-cell proliferation, protection, and imaging.

267 gly detrimental effect of aneuploidy, slowed proliferation, provides a selective benefit to cancer ce

268 phase of the mother cell, which controls the proliferation-quiescence decision in daughter cells and

269 tuating mitogenic signals are converted into proliferation-quiescence decisions is poorly understood.

270 between IVIG dose and toxin-triggered T-cell proliferation (r = -.67, P < .0001).

271 While the proliferation rate is significantly increased for a wide

272 protein synthesis in order to maintain high proliferation rates.

273 ulsions were examined for cell cytotoxicity, proliferation, redox state and migration using mouse emb

274 he mechanism of CYP24A1-mediated cancer cell proliferation remains unclear.

275 eutic effects of Tris DBA on glomerular cell proliferation, renal inflammation, and immune cells.

276 Cell differentiation and proliferation require Hedgehog (HH) signaling and aberra

277 tochord bead and for promoting wound-induced proliferation required for efficient regeneration.

278 mice reproduced ERK-driven KRT5(+)/KRT14(-) proliferation seen in injured mice; KRT14(+) cells were

279 ted B cells that optimizes cell survival and proliferation, setting the stage for oncogenic transform

280 f key oncogenes, including MYC, to provide a proliferation signal.

281 by induction of cytokine-dependent cellular proliferation, signal transduction, and transcriptome an

282 SLPE, LKPTPEGDLE, ILDKVGINY, and VLVLDTDYK), proliferation stimulating peptide (IDALNENK), and cytoto

283 Cytokines that stimulate T cell proliferation, such as interleukin (IL)-15, have been ex

284 cell cytotoxicity and dendritic cell-induced proliferation, they failed to sufficiently regulate T ce

285 n cell shape, cytoskeleton tension, and cell proliferation through the Hippo signaling effector Yki/Y

286 The contribution of cellular proliferation to viral persistence is particularly signi

287 kdown and NF2 reconstitution suppressed cell proliferation, tumour growth and invasion, both in vitro

288 We show here that AX-024 reduces T cell proliferation upon weak TCR stimulation but does not sig

289 Ghr but not DG, decreased cell proliferation via AMPK activation in cholangiocytes in v

290 -permeable proteomimetic that activates cell proliferation via regulation of the Hippo pathway, highl

291 ion into the ileum was increased; epithelial proliferation was decreased along with significantly hig

292 Lymphocyte proliferation was inhibited after 2 h of noradrenaline i

293 Kupffer cell proliferation was seen in all patients, and chronic hepa

294 5, and 10 mM) of nicotine, and cementoblast proliferation was then evaluated using a real-time cell

295 genes, indicating that tumor growth and cell proliferation were hormone dependent in addition to bein

296 Only VEGF-A stimulated HUVEC migration and proliferation whereas both GW0742 and VEGF-A promoted tu

297 f these effects are cell autonomous, such as proliferation, while others are mediated by secreted sig

298 ad increased acinar cell dropout and reduced proliferation with no difference in apoptotic cell death

299 s), outcomes were resolution of exudation or proliferation with return to baseline vision (n = 2), st

300 uced CSF1R activation and Iba1-positive cell proliferation, without a reduction of the basal Iba1-pos