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1 demonstrate that the nonclassical peroxisome proliferator 4-phenyl butyric acid is an efficient induc
2 ypothesis that variability in the Peroxisome Proliferator Activated Receptor (PPAR) pathway would be
3 Paneth cells inhibits activity of peroxisome proliferator activated receptor alpha (PPAR-alpha)(3), a
4 ne-S-transferase 4-4 (Gsta4(-/-))/peroxisome proliferator activated receptor alpha (Ppara(-/-)) doubl
5 lement binding protein 1 (CREB1), peroxisome proliferator activated receptor alpha (PPARA), and CCAAT
8 t the transcriptional activity of peroxisome proliferator activated receptor gamma (PPARgamma) to rev
9 rionic gonadotropin (hCGbeta) and peroxisome proliferator activated receptor gamma (PPARgamma) were m
13 , mitochondrial KATP channels and peroxisome proliferator activated receptor gamma coactivator-1 (PGC
15 on bodyweight loss, induction of peroxisome proliferator activated receptor-alpha (PPARalpha)-regula
17 pression of hepatic expression of peroxisome proliferator activated receptor-gamma and genes encoding
18 the steatogenic nuclear receptor peroxisome proliferator-activated gamma (PPARgamma) and its downstr
21 we investigated the impact of the peroxisome proliferator-activated receptor (PPAR) agonist GW501516
22 hesized that bezafibrate, a broad peroxisome proliferator-activated receptor (PPAR) agonist, relieves
24 we identify the nuclear receptor peroxisome proliferator-activated receptor (PPAR) delta as key regu
25 rs farnesoid X receptor (FXR) and peroxisome proliferator-activated receptor (PPAR) delta have been v
27 peroxide dismutase 2), PGC1alpha [peroxisome proliferator-activated receptor (PPAR) gamma-coactivator
28 ify circulating factors involving peroxisome proliferator-activated receptor (PPAR) pathways in the e
29 gainst decapentaplegic homologs), peroxisome proliferator-activated receptor (PPAR), and PI3K-Akt-AMP
31 e report that CD8(+) TILs enhance peroxisome proliferator-activated receptor (PPAR)-alpha signaling a
32 hepatocytes in vivo downregulated peroxisome proliferator-activated receptor (PPAR)-alpha, carnitine
36 (+30% Oil Red O stain [ORO], +50% peroxisome proliferator-activated receptor (PPAR)-gamma protein; P
37 arget of rapamycin (mTOR) and the peroxisome proliferator-activated receptor (PPAR)-gamma proteins.
38 e, this involves up-regulation of peroxisome proliferator-activated receptor (PPAR)alpha expression.
39 l peptidase 4 (DPP-4) inhibitors, peroxisome proliferator-activated receptor (PPAR-gamma/alpha/delta)
40 lated to fatty acid synthesis and peroxisome proliferator-activated receptor (PPARalpha) signaling.
41 -laden adipocytes by upregulating peroxisome proliferator-activated receptor (PPARgamma) and CCAAT/en
42 ydrocarbon receptor (AhR) and the peroxisome proliferator-activated receptor (PPARgamma); (iii) speci
43 ively advantageous allele for the peroxisome proliferator-activated receptor A (PPARA) gene, which wa
44 GSD Ia were treated with the pan-peroxisomal proliferator-activated receptor agonist, bezafibrate, to
46 s enhanced by insulin-sensitizing peroxisome proliferator-activated receptor agonists and inhibited b
47 pe 1 (CB1) or type 2 (CB2) or via peroxisome proliferator-activated receptor alpha (PPAR-alpha) stimu
48 by controlling the expression of peroxisome proliferator-activated receptor alpha (Ppara), and treat
49 nvestigate the protective role of peroxisome proliferator-activated receptor alpha (PPARalpha) agains
51 izes the ligand-binding domain of peroxisome proliferator-activated receptor alpha (PPARalpha) and in
52 REBH regulates and interacts with peroxisome proliferator-activated receptor alpha (PPARalpha) and PP
53 -activated protein kinase (AMPK), peroxisome proliferator-activated receptor alpha (PPARalpha) and PP
54 regulated phospho-Akt (p-Akt) and peroxisome proliferator-activated receptor alpha (PPARalpha) axes.
55 of transcription factors such as peroxisome proliferator-activated receptor alpha (PPARalpha) in the
59 ctivation of the nuclear receptor peroxisome proliferator-activated receptor alpha (PPARalpha) promot
60 ockdown reduced the expression of peroxisome proliferator-activated receptor alpha (PPARalpha) target
61 her Astragaloside IV can activate peroxisome proliferator-activated receptor alpha (PPARalpha) to sti
63 to a reduced abundance of mRNA of peroxisome proliferator-activated receptor alpha (PPARalpha), an IM
64 at overlaps binding sequences for peroxisome proliferator-activated receptor alpha (PPARalpha), carbo
65 afibrate, known activators of the peroxisome proliferator-activated receptor alpha (PPARalpha), induc
66 ion were known to be regulated by peroxisome proliferator-activated receptor alpha (PPARalpha), sugge
67 can activate transcription factor peroxisome proliferator-activated receptor alpha (PPARalpha), which
68 growth factor beta (TGF-beta) and peroxisome proliferator-activated receptor alpha (PPARalpha)-associ
71 ysis identifies the lipid-sensing peroxisome proliferator-activated receptor alpha (PPARalpha, NR1C1)
72 ysis unraveled that inhibition of peroxisome proliferator-activated receptor alpha activity resulting
73 toxicity, and discuss the role of peroxisome proliferator-activated receptor alpha and dysregulated f
74 eral nuclear receptors, including peroxisome proliferator-activated receptor alpha and/or liver X rec
75 noprecipitation assays identified peroxisome proliferator-activated receptor alpha as a mediator of M
76 fatty acid beta-oxidation through peroxisome proliferator-activated receptor alpha phosphorylation, t
77 AMP-activated protein kinase and peroxisome proliferator-activated receptor alpha responsive gene th
78 -fold), whereas the expression of peroxisome proliferator-activated receptor alpha target genes was s
79 factors, particularly PPARalpha (peroxisome proliferator-activated receptor alpha), and livers from
80 eased transcriptional activity of peroxisome proliferator-activated receptor alpha, the transcription
81 g protein-hepatocyte specific and peroxisome proliferator-activated receptor alpha, which are transcr
84 rnesoid X receptor (FXR) and dual peroxisome proliferator-activated receptor alpha/delta (PPAR-alpha/
85 d receptor-alpha (PPARalpha), and peroxisome proliferator-activated receptor beta/delta (PPARbeta/del
86 Nuclear receptor co-activator peroxisome proliferator-activated receptor co-activator 1 alpha (PG
88 istically, a HFD induces a robust peroxisome proliferator-activated receptor delta (PPAR-delta) signa
93 As from higher lipolysis activate peroxisome proliferator-activated receptor delta to induce FA oxida
94 ly diminished ability to activate peroxisome proliferator-activated receptor gamma (MSDC-0602) would
95 een OmpA and Ecgp96 downregulates peroxisome proliferator-activated receptor gamma (PPAR-gamma) and g
96 -6 transcript levels, and induced peroxisome proliferator-activated receptor gamma (PPAR-gamma) expre
99 Pharmacological activation of peroxisome proliferator-activated receptor gamma (PPAR-gamma) prote
101 , epithelial hypoxia derived from peroxisome proliferator-activated receptor gamma (PPAR-gamma)-depen
102 the intracellular butyrate sensor peroxisome proliferator-activated receptor gamma (PPAR-gamma).
103 al of its target genes, including peroxisome proliferator-activated receptor gamma (PPARG) and mannos
104 ranslocation variant 4 (ETV4) and peroxisome proliferator-activated receptor gamma (PPARG) as the bio
105 t, WT mice displayed up-regulated peroxisome proliferator-activated receptor gamma (Pparg) signaling
106 en-null background, we identified peroxisome proliferator-activated receptor gamma (Pparg), encoding
107 lue whale (Balaenoptera musculus) peroxisome proliferator-activated receptor gamma (PPARG), glucocort
108 possesses weak proadipogenic and peroxisome proliferator-activated receptor gamma (PPARgamma) activa
111 adipogenic transcription factors peroxisome proliferator-activated receptor gamma (PPARgamma) and C/
112 direct activation of the nuclear peroxisome proliferator-activated receptor gamma (PPARgamma) and re
113 nsport activity were blocked by a peroxisome proliferator-activated receptor gamma (PPARgamma) antago
114 phage differentiation by cleaving peroxisome proliferator-activated receptor gamma (PPARgamma) at Asp
115 report two crystal structures of peroxisome proliferator-activated receptor gamma (PPARgamma) in an
116 beta, C/EBPdelta, KLF5, KLF9, and peroxisome proliferator-activated receptor gamma (PPARgamma) in the
123 ontrast, the master adipogenic TF peroxisome proliferator-activated receptor gamma (PPARgamma) is ess
124 ice, and conditional OPC-specific peroxisome proliferator-activated receptor gamma (PPARgamma) knocko
126 cellular matrix, particularly the peroxisome proliferator-activated receptor gamma (Ppargamma) pathwa
127 pression can be regulated through peroxisome proliferator-activated receptor gamma (PPARgamma) respon
128 ruited to the promoter of Nox1, a peroxisome proliferator-activated receptor gamma (PPARgamma) target
129 e genistein, a natural agonist of peroxisome proliferator-activated receptor gamma (PPARgamma) that h
130 ng protein alpha (C/EBPalpha) and peroxisome proliferator-activated receptor gamma (PPARgamma)) and l
131 te or inhibit the activity of the peroxisome proliferator-activated receptor gamma (PPARgamma), a key
133 s of nuclear receptors, including peroxisome proliferator-activated receptor gamma (PPARgamma), are s
134 ct action on the nuclear receptor peroxisome proliferator-activated receptor gamma (PPARgamma), but t
135 inding protein family members and peroxisome proliferator-activated receptor gamma (PPARgamma), other
137 ism genes during NAFLD, including peroxisome proliferator-activated receptor gamma (PPARgamma), stero
138 ted this hypothesis on three NRs: peroxisome proliferator-activated receptor gamma (PPARgamma), vitam
139 pression is directly regulated by peroxisome proliferator-activated receptor gamma (PPARgamma), whose
140 nd activates the nuclear receptor peroxisome proliferator-activated receptor gamma (PPARgamma), yet i
141 is defect is because of defective peroxisome proliferator-activated receptor gamma (PPARgamma)-depend
142 prostaglandin J2 (PGJ2) activates peroxisome proliferator-activated receptor gamma (PPARgamma)-depend
147 ment by suppressing expression of peroxisome proliferator-activated receptor gamma 2 and lipid-drople
148 2 cells, FXR activation increased peroxisome proliferator-activated receptor gamma activity and reduc
150 kinase inhibitor SP600125 and the peroxisome proliferator-activated receptor gamma agonist rosiglitaz
151 o TPHP, found that ciglitazone (a peroxisome proliferator-activated receptor gamma agonist) and 17bet
152 ssion of the transcription factor peroxisome proliferator-activated receptor gamma and its target gen
153 landin J2-dependent activation of peroxisome proliferator-activated receptor gamma and macrophage act
154 n 2 expression and suppression of peroxisome proliferator-activated receptor gamma and p27 expression
155 g uncoupling protein 1 (Ucp1) and peroxisome proliferator-activated receptor gamma co-activator 1alph
156 ugmented acyl-coenzyme A oxidase 1 (Acox-1), proliferator-activated receptor gamma co-activator alpha
159 es uncoupling protein (UCP)-1 and peroxisome proliferator-activated receptor gamma coactivator (PGC)-
160 at ultimately increases the transcription of proliferator-activated receptor gamma coactivator 1 alph
161 he expression of four isoforms of peroxisome proliferator-activated receptor gamma coactivator 1 alph
163 ial biogenesis regulatory protein peroxisome proliferator-activated receptor gamma coactivator 1-alph
165 The transcriptional coactivator peroxisome proliferator-activated receptor gamma coactivator 1-alph
166 ranscription factors O (Foxo) and Peroxisome proliferator-activated receptor gamma coactivator 1-alph
167 ial biogenesis, in particular via peroxisome proliferator-activated receptor gamma coactivator 1-alph
169 oincided with decreased levels of peroxisome proliferator-activated receptor gamma coactivator 1-alph
170 e demonstrate, unexpectedly, that peroxisome proliferator-activated receptor gamma coactivator 1-alph
172 ependent of the activation of the peroxisome proliferator-activated receptor gamma coactivator 1-alph
173 1) and its downstream mediators: PGC-1alpha (proliferator-activated receptor gamma coactivator 1-alph
174 increased promoter methylation of peroxisome proliferator-activated receptor gamma coactivator 1-alph
175 ial respiration between legs, but peroxisome proliferator-activated receptor gamma coactivator 1-alph
176 t of melanomas display heightened peroxisome proliferator-activated receptor gamma coactivator 1-alph
177 Overexpression of coactivator peroxisome proliferator-activated receptor gamma coactivator 1-alph
178 ator of mitochondrial biogenesis, peroxisome proliferator-activated receptor gamma coactivator 1alpha
180 UCP1(+) cells also expressed the peroxisome proliferator-activated receptor gamma coactivator 1alpha
182 ATP levels, reduced expression of peroxisome proliferator-activated receptor gamma coactivator 1alpha
183 coexpression of the coactivators peroxisome proliferator-activated receptor gamma coactivator 1alpha
184 demonstrate that the coactivator peroxisome proliferator-activated receptor gamma coactivator 1alpha
185 mitochondrial DNA copy number and peroxisome proliferator-activated receptor gamma coactivator 1alpha
186 The transcriptional regulator peroxisome proliferator-activated receptor gamma coactivator 1alpha
187 ranscription factor A (TFAM), and peroxisome proliferator-activated receptor gamma coactivator 1alpha
188 reast cancer cells, IGF-1 induces peroxisome proliferator-activated receptor gamma coactivator 1beta
189 wheel running and muscle-specific peroxisome proliferator-activated receptor gamma coactivator-1 alph
190 mplex adaptive responses in which peroxisome proliferator-activated receptor gamma coactivator-1 alph
191 ntially through the regulation of peroxisome proliferator-activated receptor gamma coactivator-1alpha
192 own to regulate and interact with peroxisome proliferator-activated receptor gamma coactivator-1alpha
193 ling protein-1, deiodinase-2, and peroxisome proliferator-activated receptor gamma coactivator-1alpha
194 paired box gene 8 (PAX8) with the peroxisome proliferator-activated receptor gamma gene (PPARG), resu
196 deoxy Delta-prostaglandin J2, and peroxisome proliferator-activated receptor gamma in this response.
197 inally, application of a specific peroxisome proliferator-activated receptor gamma inhibitor abolishe
200 rminal kinase, thereby inhibiting peroxisome proliferator-activated receptor gamma through serine 84
201 ably, I148M cells display reduced peroxisome proliferator-activated receptor gamma transcriptional ac
202 lucose/lipid metabolism regulator peroxisome proliferator-activated receptor gamma was associated wit
203 ino salicylic acid, a PPAR-gamma (peroxisome proliferator-activated receptor gamma) agonist that stim
205 rget of rapamycin or reactivating peroxisome proliferator-activated receptor gamma, an LAL downstream
206 STAT6, Kruppel-like factor 4, and peroxisome proliferator-activated receptor gamma, and can reduce cy
207 lasmic reticulum, down-regulating peroxisome proliferator-activated receptor gamma, and reducing Snai
208 drial transcriptional coactivator peroxisome proliferator-activated receptor gamma, coactivator 1-alp
209 f the transcriptional coactivator peroxisome proliferator-activated receptor gamma-coactivator 1alpha
210 crophage lipid metabolism through peroxisome proliferator-activated receptor gamma-dependent regulati
211 s in rats were reported to induce peroxisome proliferator-activated receptor gamma-dependent transgen
217 es, and ameliorated activation of peroxisome proliferator-activated receptor gamma/sterol regulatory
218 ol the regulator of adipogenesis, peroxisome proliferator-activated receptor gamma2 (Ppargamma2).
219 MURF1)-mediated ubiquitylation of peroxisome proliferator-activated receptor gamma2 (PPARgamma2).
220 sions of extracellular matrix and peroxisome proliferator-activated receptor pathways in skeletal mus
221 atory mediators and repression of peroxisome proliferator-activated receptor signaling and oxidative
222 pathways, some linked to altered peroxisome proliferator-activated receptor signaling, muscle contra
223 eek due to failure to undergo the peroxisome proliferator-activated receptor signaling-dependent swit
225 pel-like factor-5) and PPARalpha (peroxisome proliferator-activated receptor) that regulate cardiac l
226 for receptor binding, while PPAR (peroxisome proliferator-activated receptor)-beta/delta and TGFbeta1
228 hanolamide (PEA), a lipid-derived peroxisome proliferator-activated receptor-alpha (PPAR-alpha) agoni
229 -activated protein kinase (AMPK), peroxisome proliferator-activated receptor-alpha (PPAR-alpha), and
230 analyses revealed marked loss of peroxisomal proliferator-activated receptor-alpha (PPARalpha) signal
231 coactivator 1-alpha (PGC-1alpha), peroxisome proliferator-activated receptor-alpha (PPARalpha), and p
233 to identify the mechanism whereby peroxisome proliferator-activated receptor-alpha confers a survival
234 ought to characterize the role of peroxisome proliferator-activated receptor-alpha in sepsis and to i
236 nhr-49 (an ortholog of the human peroxisome proliferator-activated receptor-alpha), and a key regula
237 hese results suggest that altered peroxisome proliferator-activated receptor-alpha-mediated cellular
239 e-tuned mitochondrial fitness via peroxisome proliferator-activated receptor-beta signaling, programm
241 potent, selective agonist for the peroxisome proliferator-activated receptor-delta (PPAR-delta), whic
242 mone secretagogue ibutamoren, the peroxisome proliferator-activated receptor-delta agonist GW501516,
243 xogenous AC caused an increase in peroxisome proliferator-activated receptor-gamma (PPAR-gamma) expre
244 ation of the transcription factor peroxisome proliferator-activated receptor-gamma (PPAR-gamma), whic
245 iglitazone, a specific agonist of peroxisome proliferator-activated receptor-gamma (PPAR-gamma).
246 with NAFLD, hepatic expression of peroxisome proliferator-activated receptor-gamma (PPARG) coactivato
249 Evidence suggests that targeting Peroxisome Proliferator-Activated Receptor-gamma (PPARgamma) can be
251 iabetic drugs, which activate the peroxisome proliferator-activated receptor-gamma (PPARgamma) nuclea
252 s alpha and beta (LXRalpha,beta), peroxisome proliferator-activated receptor-gamma (PPARgamma), and a
253 ent were associated with enhanced peroxisome proliferator-activated receptor-gamma (PPARgamma), insul
255 lucocorticoid receptor (GR)-, and peroxisome proliferator-activated receptor-gamma (PPARgamma)-mediat
256 othyronine increased sirtuin-1, fibrillin-1, proliferator-activated receptor-gamma 1-alpha (PGC1alpha
258 human (mini-)organ, and show that peroxisome proliferator-activated receptor-gamma agonists are promi
260 ven partially reversed ex vivo by peroxisome proliferator-activated receptor-gamma agonists, likely t
261 In addition, the up-regulated peroxisome proliferator-activated receptor-gamma and -alpha (PPAR-g
262 creased expression of PGC-1alpha (peroxisome proliferator-activated receptor-gamma coactivator 1), a
263 creased expression of PGC-1alpha (peroxisome proliferator-activated receptor-gamma coactivator 1), a
264 y the transcriptional coactivator peroxisome proliferator-activated receptor-gamma coactivator 1.
265 ased bile acid levels suppress expression of proliferator-activated receptor-gamma coactivator 1alpha
266 regulator of fatty acid metabolism, and that proliferator-activated receptor-gamma coactivator 1alpha
268 formation regulator 1 (SIRT1) and peroxisome proliferator-activated receptor-gamma coactivator-1-alph
269 chondrial biogenesis (PGC-1alpha [peroxisome proliferator-activated receptor-gamma coactivator-1alpha
270 e and thyroid hormone mediate the peroxisome proliferator-activated receptor-gamma coactivator-1alpha
271 -C12-HSL attenuates expression of peroxisome proliferator-activated receptor-gamma coactivator-1alpha
272 2 (SOD2), and increased levels of peroxisome proliferator-activated receptor-gamma coactivator-alpha
273 with cholesterol or activation of peroxisome proliferator-activated receptor-gamma with pioglitazone
274 ransferable factor able to induce peroxisome proliferator-activated receptor-gamma-mediated upregulat
275 ) released from the heart trigger peroxisome proliferator-activated receptor-gamma-mediated upregulat
276 potentiated the transcription of peroxisome proliferator-activated receptor-y coactivator 1-alpha (P
277 ailed to alter, while blockade of peroxisome proliferator-activated receptors (PPARalpha, PPARgamma)
280 PPARgamma SIGNIFICANCE STATEMENT: Peroxisome proliferator-activated receptors (PPARs) are targets for
281 er the course of the past decade, peroxisome proliferator-activated receptors (PPARs) have been ident
282 s retinoid X receptors (RXRs) and peroxisome proliferator-activated receptors (PPARs) hold therapeuti
285 fibrate (BEZ), a pan activator of peroxisome proliferator-activated receptors (PPARs), has been gener
286 repress FAO genes, antagonists of peroxisome proliferator-activated receptors (PPARs), particularly t
288 Given that some PFAS activate peroxisome proliferator-activated receptors (PPARs), we sought to a
291 in the intestine and up-regulates peroxisome proliferator-activated receptors alpha and gamma activit
293 e estrogen, aryl hydrocarbon, and peroxisome proliferator-activated receptors; and oxidative stress r
294 to determine whether downstream [peroxisome proliferator-activated-receptor alpha (PPARalpha) and th
295 sure led to pre-existing elevated peroxisome proliferators-activated receptor-gamma co-activator (PGC
296 uding estrogen receptor alpha and peroxisome proliferator activator beta and gamma, indicating that t
297 on of systemic CCL2 production by peroxisome proliferator-activator receptor alpha (PPARalpha) reduce
298 P], acetyl-CoA carboxylase [ACC], peroxisome proliferator-activator receptors [PPARs], and incretins)
299 ational analysis identified three peroxisome proliferator response elements (PPREs) within the 863-nt